LOCUS       DBEROT010000001       116583 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.01, whole genome shotgun sequence.
ACCESSION   DBEROT010000001 DBEROT010000000
VERSION     DBEROT010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 116583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 116583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..116583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.01"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(136..987)
                     /gene="srtC-3"
                     /locus_tag="ACL8CG_000001"
     CDS             complement(136..987)
                     /gene="srtC-3"
                     /locus_tag="ACL8CG_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HGS1342684.1"
                     /translation="MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFV
                     KSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(974..1867)
                     /gene="srtC-2"
                     /locus_tag="ACL8CG_000002"
     CDS             complement(974..1867)
                     /gene="srtC-2"
                     /locus_tag="ACL8CG_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HGS1342685.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEDILQKGAGLLEGASLPVGGKNTHTVITAHR
                     GLPTAELFSQLDKMKKGDIFYLHVLDQVLAYQVDQIVTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLGAMAVILLLLYRV
                     YRNRRIVKGLEKQLEGRHVKD"
     gene            complement(1854..2756)
                     /gene="srtC-1"
                     /locus_tag="ACL8CG_000003"
     CDS             complement(1854..2756)
                     /gene="srtC-1"
                     /locus_tag="ACL8CG_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HGS1342686.1"
                     /translation="MVKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            complement(3094..4275)
                     /gene="rrgC"
                     /locus_tag="ACL8CG_000004"
     CDS             complement(3094..4275)
                     /gene="rrgC"
                     /locus_tag="ACL8CG_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HGS1342687.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDDRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKTDTMTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIFVTNLPLGNY
                     RFKEVEPLAGYAVTTLDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEESGHYTPVLQNGKEVVVTSGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKPN
                     N"
     gene            complement(4322..6256)
                     /locus_tag="ACL8CG_000005"
     CDS             complement(4322..6256)
                     /locus_tag="ACL8CG_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018262 - isopeptide cross-linking
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HGS1342688.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAADNVSTAPDAVTKTL
                     TIHKLLLSEDDLKTWDTNGPKGYDGTQSSLKDLTGVVAEEIPNVYFELQKYNLTDGKE
                     KENLKDDSKWTTVHGGLTTKDGLKIETSTLKGVYRIREDRTKTTYVGPNGQVLTGSKA
                     VPALVTLPLVNNNGTVIDAHVFPKNSYNKPVVDKRIADTLNYNDQNGLSIGTKIPYVV
                     NTTIPSNATFATSFWSDEMTEGLTYNEDVTITLNNVAMDQADYEVTKGINGFNLKLTE
                     AGLAKINGKDADQKIQITYSATLNSLAVADIPESNDITYHYGNHQDHGNTPKPTKPNN
                     GQITVTKTWDSQPAPEGVKATVQLVNAKTGEKVGAPVELSENNWTYTWSGLDNSIEYK
                     VEEEYNGYSAEYTVESKGKLGVKNWKDNNPAPINPEEPRVKTYGKKFVKVDQKDTRLE
                     NAQFVVKKADSNKYIAFKSTAQQAADEKAAATAKQKLDAAVAAYTNAADKQAAQALVD
                     QAQQEYNVAYKEAKFGYVEVAGKDEAMVLTSNTDGQFQISGLAAGTYKLEEIKAPEGF
                     AKIDDVEFVVGAGSWNQGEFNYLKDVQKNDATKVVNKKITIPQTGGIGTIIFAVAGAA
                     IMGIAVYAYVKNNKDEDQLA"
     gene            complement(6489..9140)
                     /locus_tag="ACL8CG_000006"
     CDS             complement(6489..9140)
                     /locus_tag="ACL8CG_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGS1342689.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTTVETKEASTPL
                     DVVILLDNSNSMSNIRHNHAHRAEKAGEATRALVDKITSNPDNRVALVTYGSTIFDGS
                     EATVEKGVADANGKILNDSALWTFDRTTFTAKTYNYSFLNLTSDPTDIQTIKDRIPSD
                     AEELNKDKLMYQFGATFTQKALMTADDILTKQARPNSKKVIFHITDGVPTMSYPINFK
                     YTGTTQSYRTQLNNFKAKTPNSSGILLEDFVTWSADGEHKIVRGDGESYQMFTKKPVT
                     DQYGVHQILSITSMEQRAKLVSAGYRFYGTDLYLYWRDSILAYPFNSSTDWITNHGDP
                     TTWYYNGNMAQDGYDVFTVGVGVNGDPGTDEATATRFMQSISSSPDNYTNVADPSQIL
                     QELNRYFYTIVNEKKSIENGTITDPMGELIDFQLGADGRFEPADYTLTANDGSSLVNN
                     VPTGGPQNDGGLLKNAKVFYDTTEKRIRVTGLYLGTGEKVTLTYNVRLNDQFVSNKFY
                     DTNGRTTLHPKEVEKNTVRDFPIPKIRDVRKYPEITIPKEKKLGEIEFIKINKNDKKP
                     LRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENSEPA
                     GYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREYPRT
                     GGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            9656..11185
                     /gene="rlrA"
                     /locus_tag="ACL8CG_000007"
     CDS             9656..11185
                     /gene="rlrA"
                     /locus_tag="ACL8CG_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HGS1342690.1"
                     /translation="MLNKYIEKRITDKITILNILLDIRSIELDELSTLTSLQSKSLLS
                     ILQELQETFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQ
                     SFNEFTQKEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFG
                     IEIYDLNDGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFP
                     ESKEFEKLKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWN
                     QEKKTHTIQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVP
                     YYNYYEHYGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLP
                     AIPIFIILNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTK
                     EYLPYVKKQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYL
                     L"
     gene            11450..12712
                     /locus_tag="ACL8CG_000008"
     CDS             11450..12712
                     /locus_tag="ACL8CG_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1342691.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGGFPSLIHLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFICYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGF
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(12770..15094)
                     /gene="pflB"
                     /locus_tag="ACL8CG_000009"
     CDS             complement(12770..15094)
                     /gene="pflB"
                     /locus_tag="ACL8CG_000009"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGS1342692.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            15321..15452
                     /locus_tag="ACL8CG_000010"
     CDS             15321..15452
                     /locus_tag="ACL8CG_000010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342693.1"
                     /translation="MEIEKQTRKLAAGCSKHCFEVVNRTDEVSSKHCFEVADRADGV"
     gene            15487..16548
                     /gene="dinB"
                     /locus_tag="ACL8CG_000011"
     CDS             15487..16548
                     /gene="dinB"
                     /locus_tag="ACL8CG_000011"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGS1342694.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(16695..17540)
                     /locus_tag="ACL8CG_000012"
     CDS             complement(16695..17540)
                     /locus_tag="ACL8CG_000012"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGS1342695.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            17796..18665
                     /locus_tag="ACL8CG_000013"
     CDS             17796..18665
                     /locus_tag="ACL8CG_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGS1342696.1"
                     /translation="MLYVGIDVAKNKHDVTALNVQGKTVLKPLTFSNNKAGFELLDLS
                     FRQLNQDCLIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLD
                     IIFPELDKIVGKHSEYTYQLLTRYPNPQKRLEARFDKLIEIKRLTASKIQDILSIAPR
                     SIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILA
                     EIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACARF
                     SPAFKAYLKTKLE"
     gene            complement(18966..20855)
                     /locus_tag="ACL8CG_000014"
     CDS             complement(18966..20855)
                     /locus_tag="ACL8CG_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGS1342697.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            20993..22558
                     /locus_tag="ACL8CG_000015"
     CDS             20993..22558
                     /locus_tag="ACL8CG_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS1342698.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     YDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            22558..23298
                     /locus_tag="ACL8CG_000016"
     CDS             22558..23298
                     /locus_tag="ACL8CG_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1342699.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(23407..23622)
                     /locus_tag="ACL8CG_000017"
     CDS             complement(23407..23622)
                     /locus_tag="ACL8CG_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342700.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(24493..25743)
                     /gene="ilvA"
                     /locus_tag="ACL8CG_000018"
     CDS             complement(24493..25743)
                     /gene="ilvA"
                     /locus_tag="ACL8CG_000018"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGS1342701.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(25793..26149)
                     /locus_tag="ACL8CG_000019"
     CDS             complement(25793..26149)
                     /locus_tag="ACL8CG_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS1342702.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(26387..26623)
                     /locus_tag="ACL8CG_000020"
     CDS             complement(26387..26623)
                     /locus_tag="ACL8CG_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342703.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(26730..27752)
                     /gene="ilvC"
                     /locus_tag="ACL8CG_000021"
     CDS             complement(26730..27752)
                     /gene="ilvC"
                     /locus_tag="ACL8CG_000021"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS1342704.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(27818..28294)
                     /gene="ilvN"
                     /locus_tag="ACL8CG_000022"
     CDS             complement(27818..28294)
                     /gene="ilvN"
                     /locus_tag="ACL8CG_000022"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGS1342705.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(28287..29987)
                     /locus_tag="ACL8CG_000023"
     CDS             complement(28287..29987)
                     /locus_tag="ACL8CG_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGS1342706.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(30188..31855)
                     /locus_tag="ACL8CG_000024"
     CDS             complement(30188..31855)
                     /locus_tag="ACL8CG_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGS1342707.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALRD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(31858..32223)
                     /locus_tag="ACL8CG_000025"
     CDS             complement(31858..32223)
                     /locus_tag="ACL8CG_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1342708.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(32380..32568)
                     /gene="rpmB"
                     /locus_tag="ACL8CG_000026"
     CDS             complement(32380..32568)
                     /gene="rpmB"
                     /locus_tag="ACL8CG_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGS1342709.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(32684..32920)
                     /locus_tag="ACL8CG_000027"
     CDS             complement(32684..32920)
                     /locus_tag="ACL8CG_000027"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1342710.1"
                     /translation="MCGFFRYFIPKYVSESRVLYLDLDIVVRKSIDELWDLDLTAIPL
                     AAVRDDFYTHNFNSGVLLINNGMWRAENVTQDLI"
     gene            complement(33071..33169)
                     /locus_tag="ACL8CG_000028"
     CDS             complement(33071..33169)
                     /locus_tag="ACL8CG_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HGS1342711.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHLL"
     gene            complement(33424..34968)
                     /locus_tag="ACL8CG_000029"
     CDS             complement(33424..34968)
                     /locus_tag="ACL8CG_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGS1342712.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVSGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            35181..35483
                     /gene="gatC"
                     /locus_tag="ACL8CG_000030"
     CDS             35181..35483
                     /gene="gatC"
                     /locus_tag="ACL8CG_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGS1342713.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            35483..36949
                     /gene="gatA"
                     /locus_tag="ACL8CG_000031"
     CDS             35483..36949
                     /gene="gatA"
                     /locus_tag="ACL8CG_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGS1342714.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            36949..38391
                     /gene="gatB"
                     /locus_tag="ACL8CG_000032"
     CDS             36949..38391
                     /gene="gatB"
                     /locus_tag="ACL8CG_000032"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGS1342715.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            38520..39080
                     /gene="efp"
                     /locus_tag="ACL8CG_000033"
     CDS             38520..39080
                     /gene="efp"
                     /locus_tag="ACL8CG_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGS1342716.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            39102..39491
                     /locus_tag="ACL8CG_000034"
     CDS             39102..39491
                     /locus_tag="ACL8CG_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1342717.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            39484..39906
                     /gene="nusB"
                     /locus_tag="ACL8CG_000035"
     CDS             39484..39906
                     /gene="nusB"
                     /locus_tag="ACL8CG_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGS1342718.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(39955..40677)
                     /locus_tag="ACL8CG_000036"
                     /pseudo
     CDS             complement(39955..40677)
                     /locus_tag="ACL8CG_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520572.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
     gene            complement(40695..40880)
                     /gene="briC"
                     /locus_tag="ACL8CG_000037"
     CDS             complement(40695..40880)
                     /gene="briC"
                     /locus_tag="ACL8CG_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGS1342719.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(41039..41806)
                     /locus_tag="ACL8CG_000038"
     CDS             complement(41039..41806)
                     /locus_tag="ACL8CG_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGS1342720.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(41803..42669)
                     /gene="accD"
                     /locus_tag="ACL8CG_000039"
     CDS             complement(41803..42669)
                     /gene="accD"
                     /locus_tag="ACL8CG_000039"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGS1342721.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(42706..44073)
                     /gene="accC"
                     /locus_tag="ACL8CG_000040"
     CDS             complement(42706..44073)
                     /gene="accC"
                     /locus_tag="ACL8CG_000040"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGS1342722.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(44085..44507)
                     /gene="fabZ"
                     /locus_tag="ACL8CG_000041"
     CDS             complement(44085..44507)
                     /gene="fabZ"
                     /locus_tag="ACL8CG_000041"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGS1342723.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(44504..44989)
                     /gene="accB"
                     /locus_tag="ACL8CG_000042"
     CDS             complement(44504..44989)
                     /gene="accB"
                     /locus_tag="ACL8CG_000042"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGS1342724.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(44992..46227)
                     /gene="fabF"
                     /locus_tag="ACL8CG_000043"
     CDS             complement(44992..46227)
                     /gene="fabF"
                     /locus_tag="ACL8CG_000043"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGS1342725.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(46249..46980)
                     /gene="fabG"
                     /locus_tag="ACL8CG_000044"
     CDS             complement(46249..46980)
                     /gene="fabG"
                     /locus_tag="ACL8CG_000044"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGS1342726.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(47014..47934)
                     /gene="fabD"
                     /locus_tag="ACL8CG_000045"
     CDS             complement(47014..47934)
                     /gene="fabD"
                     /locus_tag="ACL8CG_000045"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGS1342727.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(47927..48901)
                     /gene="fabK"
                     /locus_tag="ACL8CG_000046"
     CDS             complement(47927..48901)
                     /gene="fabK"
                     /locus_tag="ACL8CG_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGS1342728.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(49020..49244)
                     /locus_tag="ACL8CG_000047"
     CDS             complement(49020..49244)
                     /locus_tag="ACL8CG_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS1342729.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(49304..50278)
                     /locus_tag="ACL8CG_000048"
     CDS             complement(49304..50278)
                     /locus_tag="ACL8CG_000048"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGS1342730.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(50278..50712)
                     /locus_tag="ACL8CG_000049"
     CDS             complement(50278..50712)
                     /locus_tag="ACL8CG_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS1342731.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(50806..51591)
                     /locus_tag="ACL8CG_000050"
     CDS             complement(50806..51591)
                     /locus_tag="ACL8CG_000050"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGS1342732.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            51916..53280
                     /locus_tag="ACL8CG_000051"
     CDS             51916..53280
                     /locus_tag="ACL8CG_000051"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGS1342733.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            53283..53654
                     /locus_tag="ACL8CG_000052"
     CDS             53283..53654
                     /locus_tag="ACL8CG_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGS1342734.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            53868..55142
                     /gene="serS"
                     /locus_tag="ACL8CG_000053"
     CDS             53868..55142
                     /gene="serS"
                     /locus_tag="ACL8CG_000053"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGS1342735.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(55163..56065)
                     /locus_tag="ACL8CG_000054"
     CDS             complement(55163..56065)
                     /locus_tag="ACL8CG_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGS1342736.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKRSS"
     gene            complement(56175..56723)
                     /locus_tag="ACL8CG_000055"
     CDS             complement(56175..56723)
                     /locus_tag="ACL8CG_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGS1342737.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(56941..58263)
                     /locus_tag="ACL8CG_000056"
     CDS             complement(56941..58263)
                     /locus_tag="ACL8CG_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGS1342738.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(58354..58442)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(58606..60942)
                     /locus_tag="ACL8CG_000057"
     CDS             complement(58606..60942)
                     /locus_tag="ACL8CG_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGS1342739.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYTNLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(61046..61594)
                     /locus_tag="ACL8CG_000058"
     CDS             complement(61046..61594)
                     /locus_tag="ACL8CG_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGS1342740.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(61591..61893)
                     /gene="zapA"
                     /locus_tag="ACL8CG_000059"
     CDS             complement(61591..61893)
                     /gene="zapA"
                     /locus_tag="ACL8CG_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGS1342741.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            61980..62861
                     /gene="rnhC"
                     /locus_tag="ACL8CG_000060"
     CDS             61980..62861
                     /gene="rnhC"
                     /locus_tag="ACL8CG_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGS1342742.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            62865..63479
                     /gene="lepB"
                     /locus_tag="ACL8CG_000061"
     CDS             62865..63479
                     /gene="lepB"
                     /locus_tag="ACL8CG_000061"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGS1342743.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            63607..65973
                     /locus_tag="ACL8CG_000062"
     CDS             63607..65973
                     /locus_tag="ACL8CG_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGS1342744.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPGQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNSIPAHDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(66021..67304)
                     /gene="tig"
                     /locus_tag="ACL8CG_000063"
     CDS             complement(66021..67304)
                     /gene="tig"
                     /locus_tag="ACL8CG_000063"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGS1342745.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(67465..67857)
                     /locus_tag="ACL8CG_000064"
     CDS             complement(67465..67857)
                     /locus_tag="ACL8CG_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1342746.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(68159..68749)
                     /gene="cbpG"
                     /locus_tag="ACL8CG_000065"
                     /pseudo
     CDS             complement(68159..68749)
                     /gene="cbpG"
                     /locus_tag="ACL8CG_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(68830..69069)
                     /locus_tag="ACL8CG_000066"
     CDS             complement(68830..69069)
                     /locus_tag="ACL8CG_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342747.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(69219..69824)
                     /locus_tag="ACL8CG_000067"
                     /pseudo
     CDS             complement(69219..69824)
                     /locus_tag="ACL8CG_000067"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(69746..69988)
                     /locus_tag="ACL8CG_000068"
                     /pseudo
     CDS             complement(69746..69988)
                     /locus_tag="ACL8CG_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(69989..70621)
                     /locus_tag="ACL8CG_000069"
     CDS             complement(69989..70621)
                     /locus_tag="ACL8CG_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1342748.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF"
     gene            complement(70635..71630)
                     /locus_tag="ACL8CG_000070"
     CDS             complement(70635..71630)
                     /locus_tag="ACL8CG_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1342749.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHNLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(71627..72325)
                     /gene="liaF"
                     /locus_tag="ACL8CG_000071"
     CDS             complement(71627..72325)
                     /gene="liaF"
                     /locus_tag="ACL8CG_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGS1342750.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(72402..73412)
                     /gene="fni"
                     /locus_tag="ACL8CG_000072"
     CDS             complement(72402..73412)
                     /gene="fni"
                     /locus_tag="ACL8CG_000072"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGS1342751.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(73396..74403)
                     /locus_tag="ACL8CG_000073"
     CDS             complement(73396..74403)
                     /locus_tag="ACL8CG_000073"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGS1342752.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(74390..75343)
                     /gene="mvaD"
                     /locus_tag="ACL8CG_000074"
     CDS             complement(74390..75343)
                     /gene="mvaD"
                     /locus_tag="ACL8CG_000074"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGS1342753.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(75325..76203)
                     /gene="mvk"
                     /locus_tag="ACL8CG_000075"
     CDS             complement(75325..76203)
                     /gene="mvk"
                     /locus_tag="ACL8CG_000075"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGS1342754.1"
                     /translation="MTKKVGIGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(76325..77344)
                     /gene="cbpC"
                     /locus_tag="ACL8CG_000076"
     CDS             complement(76325..77344)
                     /gene="cbpC"
                     /locus_tag="ACL8CG_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGS1342755.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(77442..78131)
                     /locus_tag="ACL8CG_000077"
     CDS             complement(77442..78131)
                     /locus_tag="ACL8CG_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1342756.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTIQE"
     gene            complement(78143..79567)
                     /gene="gndA"
                     /locus_tag="ACL8CG_000078"
     CDS             complement(78143..79567)
                     /gene="gndA"
                     /locus_tag="ACL8CG_000078"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGS1342757.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(79643..81037)
                     /gene="mapZ"
                     /locus_tag="ACL8CG_000079"
     CDS             complement(79643..81037)
                     /gene="mapZ"
                     /locus_tag="ACL8CG_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGS1342758.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PFSEDILLPLPLDDEEQGLDPLLLEDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(81050..82207)
                     /locus_tag="ACL8CG_000080"
     CDS             complement(81050..82207)
                     /locus_tag="ACL8CG_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGS1342759.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARVVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(82292..82672)
                     /gene="rnpB"
                     /locus_tag="ACL8CG_000081"
     ncRNA           complement(82292..82672)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL8CG_000081"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(82693..83022)
                     /gene="gpsB"
                     /locus_tag="ACL8CG_000082"
     CDS             complement(82693..83022)
                     /gene="gpsB"
                     /locus_tag="ACL8CG_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGS1342760.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(83092..83619)
                     /locus_tag="ACL8CG_000083"
     CDS             complement(83092..83619)
                     /locus_tag="ACL8CG_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGS1342761.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            83685..84281
                     /gene="recU"
                     /locus_tag="ACL8CG_000084"
     CDS             83685..84281
                     /gene="recU"
                     /locus_tag="ACL8CG_000084"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGS1342762.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            84278..86437
                     /gene="pbp1a"
                     /locus_tag="ACL8CG_000085"
     CDS             84278..86437
                     /gene="pbp1a"
                     /locus_tag="ACL8CG_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGS1342763.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(86604..91907)
                     /locus_tag="ACL8CG_000086"
     CDS             complement(86604..91907)
                     /locus_tag="ACL8CG_000086"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGS1342764.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKIFLKAGSYDDERTVVSVRTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKALKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQDWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDSSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTAESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKSDAPTVEKPEFKLSSLASEQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(92208..94190)
                     /locus_tag="ACL8CG_000087"
     CDS             complement(92208..94190)
                     /locus_tag="ACL8CG_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1342765.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            94509..94901
                     /locus_tag="ACL8CG_000088"
                     /pseudo
     CDS             94509..94901
                     /locus_tag="ACL8CG_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(94990..95823)
                     /locus_tag="ACL8CG_000089"
     CDS             complement(94990..95823)
                     /locus_tag="ACL8CG_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HGS1342766.1"
                     /translation="MKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLFEGTLEL
                     LDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYIKENYPK
                     SKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEILSTKDV
                     PFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRKKLNYSL
                     FETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQGSIKPTYTFKNVKEMWKGI
                     V"
     gene            complement(95838..96542)
                     /locus_tag="ACL8CG_000090"
     CDS             complement(95838..96542)
                     /locus_tag="ACL8CG_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HGS1342767.1"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGTYIEESMKVVEKNGRLVEISKQISPEEAL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILPEVEFIACPLDGRWL
                     EIDNHEDLAVAEKLFA"
     gene            complement(96558..97586)
                     /locus_tag="ACL8CG_000091"
     CDS             complement(96558..97586)
                     /locus_tag="ACL8CG_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HGS1342768.1"
                     /translation="MKNNDLKIGSGAIHQISATLSQNNISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDAVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     gene            complement(97622..98770)
                     /locus_tag="ACL8CG_000092"
     CDS             complement(97622..98770)
                     /locus_tag="ACL8CG_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol--glycerophosphate
                     glycerophosphotransferase"
                     /protein_id="HGS1342769.1"
                     /translation="MVVLQNVKFLVRVVFMVIISIVLWPVRIKKNKILFINFNGKGYG
                     DNPKSICEYLRVTYPELDLVWLAKDNEDFPDGVRVVRYKSLQSFYEQASSKVWVYNVR
                     NFERLLKKRGQFYIQTWHGASSFKLIEKQADLPLKYILEAKYDARVTDIMISDSRKQT
                     EEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKELSIDSDDYVILYAPTFRD
                     DGDASYLDINFERLLQSIEQEIKKKCKILIRLHPNDSHFSNNISFNHDIIDVTLFSDM
                     QELILLADVLLTDYSSAIFDFMLLNKPYVRYVNDLEKYAELRGLSDTYYELPDPIIKT
                     AEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGRRIIQEL"
     gene            complement(98772..99272)
                     /locus_tag="ACL8CG_000093"
     CDS             complement(98772..99272)
                     /locus_tag="ACL8CG_000093"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS1342770.1"
                     /translation="MLLLFSFIMEATISDSIFYRNFLFMGIPFFGIGILIAQNQKKII
                     NCKIINKILILGTIIYPILIFLEYYILGNSFEVYISSVLATIILMIFAIKSPKAINIK
                     ILNGIGDKYATFVYIIHQFIIVIFKFLVSNVYILKFGTIFVFLICCFLGVLFQFIKNR
                     LLKRFS"
     gene            complement(99361..99606)
                     /locus_tag="ACL8CG_000094"
     CDS             complement(99361..99606)
                     /locus_tag="ACL8CG_000094"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS1342771.1"
                     /translation="MVTKDKGLTYNSTLHAIKVLACFSVVAIHIWLPGKIGAFYQIIA
                     RFAVPMFFLISGFYSYNISKNRIKKIFRLILRSTFFM"
     gene            complement(99964..101427)
                     /locus_tag="ACL8CG_000095"
     CDS             complement(99964..101427)
                     /locus_tag="ACL8CG_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HGS1342772.1"
                     /translation="MSNKISKNLAYNMGYQLIGIAAPLITSPYLSRILGAENLGIHSF
                     TMSVALYFMMFMLLGIANYGNRTIATVKREGKDILSKTFWSIYSIQLIMSILVTIAYL
                     AYLYLGAVHYKVIAILQLFLLLSNAVDITWFFYGLENFKQIVFRNTLVKLLGLFLIFL
                     CVRQGTDLWKYTFINGSVTLVGQLLLWGQLKGILTWKKIQLKELLPHIKPILILFIPV
                     LAISIFTNMDKYMLGLMVDVKQVGFYDNAGRIIEIPKALIAALGAVMLPRTSYLLAEG
                     QKEKSKYYIEVTILYVMIISSVLMFGLISVSDIFSIIFWGEEFLESGRLISAMSPAFV
                     FSVLGNIIRTQYLIPRAKDKDYVVSLIAGAVVNLVLNYFFIKPFGAMGATVSTVLAEF
                     VLSGMQFWSVRRDLDLKRYLKNGLIFYLFGLIMYLVIITLKTQLPYNIMSLILLIVLG
                     GIVYVIFCCCYILMSRNLHFKLLKEKIIRKVVHKNTL"
     gene            complement(101432..102340)
                     /locus_tag="ACL8CG_000096"
     CDS             complement(101432..102340)
                     /locus_tag="ACL8CG_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000570495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HGS1342773.1"
                     /translation="MIEKILDSIKNHSFYSKLKDKIHRIIPLYIIKNQNIAFQQDTDI
                     AYRKLKKKFRHISLTGDELKYKMEFSNKVWICWFQGEEHAPELIKTCIQSMRNQLQGR
                     EIIVLTEKNISDYTEIPGYIIEKYKKGWISRAHYSDILRIDLLCRHGGLWVDATVLNT
                     GGDFSNLEVPLFVYKSLNLSRKDSQAIVASSWLISSYSNHPILLYTRKLLWAYWRRKN
                     SLCNYFLFHICFTIATERYPIEWSAVPTFNNHSPHILHFELNEQFSEKRWEQLKHISA
                     FHKLNHHIDYSSGVNTFYKFIVSSKV"
     gene            complement(102356..103312)
                     /locus_tag="ACL8CG_000097"
     CDS             complement(102356..103312)
                     /locus_tag="ACL8CG_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1342774.1"
                     /translation="MEDLISIVVPVYNVEKYLKKSIESVLNQTYQNIEILLVDDGSTD
                     SSGKICESFSKVDPRIRVFHKENGGLSDARNFGIEQMKGQYVAFIDSDDYISKDYVWK
                     LYSSIKNNDSEVSICSFLLVDEKGEKIKDELLDSGKICLTGQQILEKVLTADGYRYVV
                     AWNKLYRSTLFEKLKFKKGMLYEDEFLNYPLFWDCKRVSIVEEPLYLYVQRKGSIVQS
                     NMTLEKIKMKDEMHTSRIEFYSEKGHSFLHEKACQQYCNWIVTATTNHSKILNPNFSK
                     YLQRQFRKFAKYTRNNDIRLIVQNILGFIDIRLAAYVKSKVM"
     gene            complement(103320..104348)
                     /locus_tag="ACL8CG_000098"
     CDS             complement(103320..104348)
                     /locus_tag="ACL8CG_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1342775.1"
                     /translation="MEIQISVVIPVYNAENTINNCIESALKQDLESFEVILVNDGSND
                     STSRILEQYSDNPQVKIFHQVNMGVSAARNLGLSHASGEYVFFLDSDDILDDGMLSKM
                     YQFVKNNKVDLLSCWHKEPATTQYGGNENKSTSFIARTREEIGAHFVDIFPRSACAKL
                     FFRKIIEENNITFSTEMSLGEDMSFVYQYLMVSKSIGVIDGVYYNIQNVNPQSLSKRY
                     VQNIENSLMIQNQLWNQLLEVYPKIEENYYKQHMDFRFYLANLYVNNLFKFDSPYSSK
                     EKLDQIAQQLKKYRLFLDEKVSKEKMPKNINEMIVFYLLKLKIPVLIYSFYSFKEWWK
                     RRKIKNEG"
     gene            complement(104350..105432)
                     /locus_tag="ACL8CG_000099"
     CDS             complement(104350..105432)
                     /locus_tag="ACL8CG_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-carotene 15,15'-monooxygenase"
                     /protein_id="HGS1342776.1"
                     /translation="MAAAVIVFVDSYSAGKIRVKNPHISLMLFFILLIFLLISFTWGT
                     LNIYGFVMRGRYILGAFLVYFMTNSYLDDRTFSSLINIAYFMQILNLLLVLHQNIVLH
                     LHPDFTNGIFGFTNYANGIQGFYCLALSVLSTVYYLYGKWGTMKSLILIAISCIICAL
                     AEIKIFFVIFIFSIILIFIFQKSETVKKIRIISTAAGISLLFLIAYKLIEIVLPDNLY
                     TFFNVTKALSYENRTEFAGRTNTISFLWDNLFYHDYISAIFGKGLGSYSVNYIYELGK
                     MLADGGFISVILLYSFLLSLFIRGTITRGKNKQSERLIVSIIAFVVMISIIVWNSTFT
                     RSTYLVFFFLAIGNAAYKSTKLIRRD"
     gene            complement(105542..106048)
                     /locus_tag="ACL8CG_000100"
     CDS             complement(105542..106048)
                     /locus_tag="ACL8CG_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1342777.1"
                     /translation="MIFVTVGTHEQQFNRLIKEVDRLKGEGFIQDDVFIQTGYSNYVP
                     KFCKWEKLISYEKMNQFIEEADTIITHGGPATFMAVIAKGKSPIIVPRLKKFGEHVND
                     HQLEFVEKVLNVYNLTVITNISDLNSYISNFDERKKSDLKSKNNLFMEKFIDMINQLM
                     ETGDIKYD"
     gene            complement(106048..106497)
                     /locus_tag="ACL8CG_000101"
     CDS             complement(106048..106497)
                     /locus_tag="ACL8CG_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--LPS N-acetylglucosamine
                     transferase"
                     /protein_id="HGS1342778.1"
                     /translation="MKICLVGSSGGHLTHLYLLKPFWKDKERFWVTFDKADARSVLSE
                     EVVYPCYYPTNRNIKNLIKNTFLAYKILKKERPDLIISSGAAIAVPFFYIGKLFGSKT
                     VYIEVFDRIDASTLTGKLVYPVTDRFIVQWEEMKKVYPKAINLGGIF"
     gene            complement(106501..107868)
                     /locus_tag="ACL8CG_000102"
     CDS             complement(106501..107868)
                     /locus_tag="ACL8CG_000102"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS1342779.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGKL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLASIVLVPLIRKDGGSTIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            complement(107883..108572)
                     /locus_tag="ACL8CG_000103"
     CDS             complement(107883..108572)
                     /locus_tag="ACL8CG_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGS1342780.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            complement(108582..109274)
                     /locus_tag="ACL8CG_000104"
     CDS             complement(108582..109274)
                     /locus_tag="ACL8CG_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HGS1342781.1"
                     /translation="MEEQNTLEIDVLQLFRSLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRDQGEKSGLTNQDLQAGTYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGLVPDLDKMK"
     gene            complement(109283..110014)
                     /gene="cps4B"
                     /locus_tag="ACL8CG_000105"
     CDS             complement(109283..110014)
                     /gene="cps4B"
                     /locus_tag="ACL8CG_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGS1342782.1"
                     /translation="MIDVHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFVDNPRKIIMDQLI"
     gene            complement(110016..111461)
                     /gene="cps4A"
                     /locus_tag="ACL8CG_000106"
     CDS             complement(110016..111461)
                     /gene="cps4A"
                     /locus_tag="ACL8CG_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGS1342783.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AIPDSNLYVMEIDDSSLAVVKAAIEDVMEGR"
     gene            111682..112202
                     /locus_tag="ACL8CG_000107"
                     /pseudo
     CDS             111682..112202
                     /locus_tag="ACL8CG_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(112195..112368)
                     /locus_tag="ACL8CG_000108"
     CDS             complement(112195..112368)
                     /locus_tag="ACL8CG_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGS1342784.1"
                     /translation="MNIKKRVLSAGMTFASALLLAACGQSGSDTKTYSSTFGGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(112528..114135)
                     /locus_tag="ACL8CG_000109"
     CDS             complement(112528..114135)
                     /locus_tag="ACL8CG_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGS1342785.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            114288..115772
                     /locus_tag="ACL8CG_000110"
     CDS             114288..115772
                     /locus_tag="ACL8CG_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGS1342786.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            115867..116349
                     /locus_tag="ACL8CG_000111"
     CDS             115867..116349
                     /locus_tag="ACL8CG_000111"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGS1342787.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(116416..>116583)
                     /locus_tag="ACL8CG_000112"
     CDS             complement(116416..>116583)
                     /locus_tag="ACL8CG_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGS1342788.1"
                     /translation="VPKWIADKVSGWGDHYQLVAQKSVLKRAISKPVLEKRGLVSCLD
                     YYLERHALKVS"
BASE COUNT        34759 a        25927 c        20614 g        35283 t
ORIGIN      
        1 cggattttta tcgctctgaa tatcaaaaaa gaaaggacaa aatttgtcct ttctcgagct
       61 tagctttttt tcaacccact acagttgaca aagagccgga aaaaggaaca gccttagctt
      121 tcctttcatt tctttttatt tccctcgtag taaacgtgct agcttccaca aaacaaacag
      181 gattcccaga aatgccagta ccactagccc acggtacaac cattgagagg ttgcaacacg
      241 cgatacagat tgtccttctt tcgtaaaagc aaccctcgca actgcagctg tttgtggatc
      301 tgatttttga taaacagcga ctcgttcaaa attcactaat aagcgtttat taaaggtagg
      361 aatcggatcg caggttatca aggtcatgat atttttagag ctaaccgatt ctaatttttc
      421 ccattccgac ggtaaaataa tctctgtgtc catcatctga tattctacaa tttcctggcc
      481 attatcataa taaagagcat ctccaacttt tagctgatcc aaatggcgga aaaagacatg
      541 gcttggctct gcacggtgcc cagcaatcac tgagcgaatc cctgtaccat ccagaggcag
      601 cggtgtacca tccacatgag ccaagcccat ccctaaatga tgataatctg ctcccaaata
      661 aaccggctcc atgatttcca aacttggaat agacaagtaa ccatagactg catcagggtc
      721 gtcagacact tggtaattga cctcatatcc ctccgccaaa aaaggatcta caatgcgatt
      781 ttgcgaagcc aagcgttgat tgtaggcgag agaatggttc tgttgttctt ggtacatttc
      841 agttgtcatg gatttcacaa atgtagcatg acctttcacc tgtccaagag actgcaacac
      901 catctgtcca aaacaataaa taggaatcaa acaggctacc aacatcaaca agtatcccaa
      961 taaggctcgt agtttagtcc ttgacatgac gcccctccaa ttgcttttct agtcctttga
     1021 caatccgtcg attacgatac acgcgataca gcaagagaag gatgaccgcc atcgctccta
     1081 gtaataacca caaccagaat tgcccacgct ctctcaccgc tcgattccgc tctgcaattg
     1141 gtgccgtata cggaatccgc ttcccacgta ccaacagacg atgactgtta atcatatacg
     1201 gtgtacaagt caacaaggtc gcataatctt ccccatgttg aatcaagaca ggctcaaagt
     1261 cattcggctc caccgtcact atctgatcca cttggtaggc caacacctga tctaaaacgt
     1321 gaagataaaa gatatcccct tttttcatct tatccaattg actgaacaat tctgccgttg
     1381 gcaatcctct gtgagcagtg atcactgtat gggtattttt acctccaaca ggcagcgaag
     1441 ccccttctaa cagccctgcc cctttctgaa gaatgtcctc actcgttccg acatacatcg
     1501 gaatttcctg atcaatcgca ggaatttcca catagccaat ccgctcatgg acctttagca
     1561 tattggcata ttctgagacg cctttctttt tctcttgctc tgtaaaagga tcaagaattt
     1621 cagatggttt caaggtcgca ttgaaggctt gagccaagcg ccaacgctcc tcaagttctg
     1681 ccttatccat ctgggaaacc gtctcatcaa actctttaat aacctcgttt gactcaatac
     1741 gataataata acgagacacc aatggatata tcgcaacggc gaatcctact aagaaaatca
     1801 gaagaaggat cagcggatgt ttcttctttt ttgtgccttt ttttcgtgaa cgtctactgt
     1861 tgtccatcct ccaccttcac ttccttcctt gctgctttca gcgccttcaa agccttttcc
     1921 ggttgttttt tcttcttgcg caagcgtcga ataatccata aaagaatcac aatcaaacca
     1981 actgccacat aaaacaggta gcgatagaga tgactgagtt tgtttgctgc aataaattct
     2041 tcctcaacct ctgctacgta cggtatccga tgcccccgaa ccaatagacg atgggtattg
     2101 atcatgtatg gcgtacaagt cagcaaggtc acataatcat gacctggtac aatcaataaa
     2161 tcatcaaagt tcgtcggctc aatcaccttt acttgatcca cttgataggc catcacttcc
     2221 ttgatattgt gcacataaaa cttatcccca actttaagtt tggtcaaatc cgtaaacatc
     2281 ttagctgttg gcaaacctgt atgtgccgta atcaccgcat gggtcgaatt gcctccgatc
     2341 ggcagagaag ttccctctag atgcccagcc ccttgctgca atacctcttc agcagtacca
     2401 gcataaaccg gcaaatccac gtcaataacg gggatttcca catgccccat ccgctcatgg
     2461 atttctaaca tacgtgcata ctctgctcgc ccttttttct tcatttcttc cgaccaagga
     2521 tcgccactca ctacattatt caaagagtca ttgaaggctt gtgccaattt cattcgttca
     2581 tcaatgtcag cctcatccaa cgttgctttt tccttatcaa agtcagcaat ttgttgattt
     2641 gattccactc gataatacaa gcgagacacc agcggatacg ccattaccgc cattccaatg
     2701 aaaaatacca ctcctaatag gagattattt cgtttttgct tttttgtttt taccattttt
     2761 atcagcatcc ctttatcttc aaactcatca ttttatcgct tttcctaaca gacaatccta
     2821 tctgctaaga gaaacgagaa aatctcattt ctttctgatt caccatccat tttaaatcag
     2881 aatcccagtc ctgtccattc ctaaaatgat taccagacca gtcctatcgt tttacaaaca
     2941 ataacccaca atgaggctgg cacaatctgc ccagcctcat atccgttatt gtgattcatg
     3001 ccacatcacc atgattcctg attaacatca cctcagagta ctctggtctt cccttcagcc
     3061 tgctatcttt ttcataatga tgtacattga atatcagtta tttggttttt tcgtaagata
     3121 ataaccacta ccaaacaaca aaatggcaac aagcatcaag atatacaagg tttcttcccc
     3181 tgtatctggc acatcaatcc gtggtcgctt gttattttta accactgtta ccagttcctt
     3241 acgagtatct ttcccgattg taaaggaaac aggcgatgtt aattgaacat aaccagttgg
     3301 agcttggagc tcccataaat agtatgtccc atactctaga ccttccactc ggaaacgacc
     3361 atctttccct gatgttacaa ctacttcctt accattttga agaacaggag tatagtgtcc
     3421 gctttcttct ttcatgactt tgaacattgc cccttgaaga gaggtattgg tccgaccatc
     3481 caccttcata aagtcaacat tgccacgtgg taatttctga ttgacaaccg taatcgtcac
     3541 cagctgatga tctaccagct ggacatccgt atccagcgtc gtaacagcat agcctgccag
     3601 tggctccacc tccttgaaac gatagttccc aagaggaaga tttgtcacaa aaatctctcc
     3661 atttttatca gtatagagag ttctccctac ttgaccagaa gaactgtaac ggtattctcc
     3721 aatcaaggga acctcttttt cagaaccatc tcttgctact gataccaatt taaagccgac
     3781 accctccaag cgattgtggt cttgatccac ctttatcagc ttcacctttg ttgtcattgt
     3841 atctgttttt ttcgctacaa tgaccaaagg ctctaccgtt tgatctgtca tttcaaaaag
     3901 aaattcagct ggataagaaa ccgcatccgt ctggataata gagcgaacat agtaaagacc
     3961 atttggaata tgagatactt caatctgatt ctcaaggaag gtcatctcaa acgaagtctt
     4021 tttgaaagaa gaaagtttat tctcatccca cgaatgcaag tctcttacaa tttgcacccg
     4081 atcatcatag gaatacgaat catccaactt ccatacttgc aaccgatgac catcacgaga
     4141 tggcaattga ctaaccacct cctgatagtt ctccaattgc aagaccaacg tgtgatcttc
     4201 ttgcgcttgg actgcatgtg caccccatac aagagaaaaa cacagagcca taacaaagaa
     4261 gatacgacta atcattttct gcattttctg cattgtcatc aatggctcct ttctctctta
     4321 cttaagcaag ttgatcctca tctttgttgt ttttaacata tgcgtacact gcaataccca
     4381 taatcgcagc ccccgctaca gcaaagataa ttgtaccaat accacccgtt tgtgggatag
     4441 tgattttttt gttgactact tttgtagcgt cattcttttg aacatctttt aagtaattaa
     4501 actcaccttg attccaagaa cctgctccaa caacaaattc tacatcatca attttcgcaa
     4561 aaccttctgg agctttaatt tcttctaatt tataagtacc agcagcaaga cctgaaattt
     4621 ggaattgacc atccgtatta gaagtaagaa ccattgcttc atcttttcca gctacttcaa
     4681 cataaccaaa tttggcttct ttgtaagcta cattgtattc ttgctgtgct tgatctacta
     4741 gagcttgagc ggcttgctta tctgcagcat ttgtgtaagc tgctaccgct gcatccaatt
     4801 tttgttttgc agttgctgct gctttttcat ctgcagcttg ttgtgcagtt gacttaaagg
     4861 caatatattt attgctatct gcttttttaa caacgaactg cgcattttct agacgagtat
     4921 ctttttggtc tactttgaca aactttttac cgtatgtttt tacacgtggt tcttcaggat
     4981 tgattggagc tgggttatta tctttccagt tttttacccc caacttccct ttgctctcta
     5041 ctgtgtattc agctgagtat ccattatatt cttcttcaac tttgtattca atagaattat
     5101 ctagaccact ccaagtatat gtccaattat tttctgaaag ttctacagga gcaccgactt
     5161 tctcaccagt cttggcattt acaagttgaa cagtcgcttt caccccctca ggagcaggtt
     5221 gactgtccca tgtcttagtt actgtaattt gaccattatt aggtttagtt ggttttggag
     5281 tattcccatg atcttgatga tttccgtaat gatatgtaat atcgttactt tcaggaatgt
     5341 ctgcaacagc aagtgagttc aaagtagctg agtaagtaat ttggattttt tggtctgcat
     5401 ccttaccatt aattttagct aaacctgctt ctgttaattt taagttaaag ccattaattc
     5461 ctttagtgac ttcataatca gcttgatcca tagctacatt attcaaagta attgttacat
     5521 cttcattata agttagacct tctgtcattt catctgacca aaatgaagtt gcaaatgttg
     5581 cattacttgg aattgttgta ttaacaacat atgggatttt agtaccgata gacagaccat
     5641 tttgatcgtt ataattcaaa gtatcagcaa ttcttttatc tacaactggt ttattatatg
     5701 aatttttagg gaaaacatgt gcatcaatta ctgtaccatt attgttaaca agtggaagag
     5761 ttacaagagc aggtacggct tttgaacctg ttaatacttg cccattagga ccaacatagg
     5821 tagtctttgt tctatcctca cgaatacgat acacaccttt aagagtactg gtttcaattt
     5881 taagtccatc tttagttgtc aaaccaccat gaactgttgt ccatttacta tcatctttaa
     5941 gattttcttt ttccttacca tcagtcaaat tatacttttg taattcaaag tatacatttg
     6001 gaatttcctc agctacaact ccagttaaat cttttaaact agattgagtt ccatcatatc
     6061 ctttaggacc gtttgtatcc caagtcttta aatcatcttc tgagagcagt aacttatgga
     6121 ttgttaaagt tttagtaaca gcatctggtg ctgtactaac attgtccgcc gcaaaaactg
     6181 ttgcagctga aaacaggcta ctcgctgtca gtaataaggc agcaagcatt gttaaaaatt
     6241 tgttgattga tttcatgatt tctccttatt catatctctt aaaatcaact gtgagcaatg
     6301 taatgaatta cacatgacaa taataatcct tttttctgtg caagttttcg aaaacatctc
     6361 ccctttcaat ggtggtttac ttggcgaaga aaactgtttt caccaagtaa acttaaatct
     6421 cttcttgagt gctacttctt aaaagtatcg ctcagagtat cgatattatc atttctcatt
     6481 gctacacttt acggatgttt ccgtgtgtat aatagaactc ctcccatcat catgcaacct
     6541 atcagataga atggcaacat tccgatacca ccagttcgag gatattctct ttttggagga
     6601 attggctcat ttgtgatata gtgcttatca ttcgtaaact cgtaacccgc tggtatatct
     6661 tgtggaacga ttgaagtcac atctctgact tctccattta ctatttggaa ggcaacgata
     6721 ggcttatttt gaacgggttt ataaccagct ggttcagaat tttcaaataa tcgatatttc
     6781 ccatctgaca gatttttaaa ggtcaactta ccatcttcac ctgttctcac attttgataa
     6841 gtgccatttt gatcaatagc tccataaata tctggataat ccggatgttg tttttgaaga
     6901 ctaaagaccg catctctcag tggtttttta tcattcttat tgatcttaat aaactcaatt
     6961 tcaccaagtt ttttctcttt tggaattgtg atttctggat actttcgtac atcacgaatc
     7021 ttaggaatcg ggaagtcgcg cactgtgttc ttttctactt ccttagggtg tagggttgtt
     7081 cgaccattcg tgtcatagaa tttattgctt acaaattggt cattcaagcg aacattataa
     7141 gtcaatgtaa ctttttcacc cgttccaagg tacaaacctg ttacacgaat ccttttctca
     7201 gtcgtatcat agaacacttt tgcatttttt agcaagccac catcattttg tggtccccca
     7261 gtagggacat tattcaccaa cgaactacca tcgtttgcag ttaaagtgta atccgctggc
     7321 tcaaaccttc catctgctcc caattggaaa tcaattagtt cacccatcgg gtctgtaatc
     7381 gtaccatttt cgatagattt cttctcattg acgatagtat agaagtagcg attcaattct
     7441 tgtaaaatct gagatggatc tgctacgtta gtgtagttgt caggagaact agagatgctc
     7501 tgcataaatc tagtagccgt tgcttcatcc gtaccaggat ccccgtttac accaacccca
     7561 acagtgaaga catcatagcc atcctgagcc atatttccgt tataatacca agtcgtaggg
     7621 tcaccatggt tggtaatcca atcggtacta gagttaaatg gataggctag aatactatca
     7681 cgccaatata aatacaagtc agttccatag aacctatatc ccgctgaaac taatttagct
     7741 ctctgctcca tggaggtgat tgaaagtatt tgatgaactc cgtattggtc tgttacaggt
     7801 ttcttcgtaa acatctgata actttcacca tctccacgaa caatcttatg ttcaccatct
     7861 gctgaccatg taacaaagtc ctccagtaat atcccgctac tatttggagt ttttgcttta
     7921 aaattattca gctgagttct gtacgattgc gtcgttcctg tatatttaaa attaattgga
     7981 tatgacatag tcggaacacc atctgtaatg tggaaaataa cctttttact gtttggtctt
     8041 gcctgctttg tcaagatatc atcagcggtc atcaaagcct tctgggtaaa agtcgcgccg
     8101 aattgataca tcaatttgtc tttgttcaat tcctctgcat ctgatggaat cctatcctta
     8161 atagtttgaa tatcagtagg atctgatgtg agatttaaaa agctataatt ataagtttta
     8221 gctgtaaacg tcgtacgatc gaacgtccat aaagctgagt cattcaatat ttttccgttc
     8281 gcatctgcta cccctttttc cacagtagct tctgaaccgt caaagatagt tgagccataa
     8341 gtcacaagtg ctactcgatt atctggattg gaggtaatct tatctacaag ggctcgtgtc
     8401 gcttctcccg ctttttccgc tcgatgggca tgattatgtc gaatattact catactattg
     8461 gagttatcta atagaataac aacatctagc ggagtagagg cttctttcgt ttcaaccgtc
     8521 gttttaccac taaccgtcaa ctcgattcca tattggttat catccaaatt attcacttga
     8581 taaattctct ttgaaagtgt accttctgga atcacacgtt catatggatt cggattcaac
     8641 gccttgtgct gtccgttttt ttccgaacca tctaccttaa taatctgata aggtgtttga
     8701 acatctggat aagtccctgt ttgtggatac tggtcagata gagcctcttc tcgattttct
     8761 acctgttcac cttggacagt cgtccgacca ttcttctcaa cttcaacagt ccattgttta
     8821 gtagagggtt tataaccaac tggaggttgg gcttctgtca aggtgtatgt cccaggtttt
     8881 atgtttgaaa atatcgcttc tcctgtttgc gcctctgtcc tttgcgaaac agttgtgcca
     8941 tccgtattgt ttttcaactc aaagacggca tctcctagaa gcgctcctcc ttcgcctgtc
     9001 tccttaatca ctacttttcc tatcgctgga ctggtttcag gcgtttctgc taaagcaact
     9061 atcgaagaaa aagctgtcaa ctgagatata cagcacagtc ctgcaactgc cttctgaaat
     9121 atctttctta cttttttcat gtgtgtctcc ctgttaagca ttattcatag aacaagttaa
     9181 tccttctatg attcataggt actttcaatc tgtatacacg aagaaacgga ttacttatgt
     9241 tctgataaaa tttatctcac tgagttaatc cgttcactaa caaacgtagc aaaagcgtat
     9301 aaaagtgcgt tatagctatc ttctcaacct ggcaatgaca cacttgtata caatatagta
     9361 tagtatagta ttactattaa ctatcctagt ataaattaaa acaacttcca tcacaataga
     9421 tatttttatc acatattttt ttatagaacg acaatatttg ataaaaaaat attttctaat
     9481 aaaaaaaata agccataaaa ctccaccaat actcattact atctttaaaa tgccttttat
     9541 tacatgctgt tttatcaata aagtcggaaa ttccacaacc tttttgacaa gacaattagt
     9601 ttcttttgta ttataataat taaaattatc tatatgcaac taagattcgg taactatgct
     9661 aaacaaatac attgaaaaaa gaattacaga taaaattacc attttaaata tattattgga
     9721 tattcggtct attgaactag atgaactgtc tactttaact tcattacaat ctaaaagtct
     9781 cctaagcatt ttgcaggaat tacaagaaac attcgaggaa gagttgacat ttaatttaga
     9841 tacgcaacaa gttcaattaa tcgaacacca ttctcatcaa acgaattatt acttccatca
     9901 gctttataac caatcaacta ttttaaaaat actccgcttc tttctactac aaggtaatca
     9961 aagctttaac gaatttacac aaaaagagta tatttccatc gcaacaggct accgcgtacg
    10021 acaaaagtgt ggcttgttac tacgttcagt aggtttggac cttgtgaaaa atcaagtagt
    10081 tggtcctgaa tatcgcattc gttttttaat tgcactcctc cagtttcatt ttggtattga
    10141 gatttatgat ttgaatgatg gaagtatgga ttgggtcaca catatgattg tgcagtctaa
    10201 ttctcaactc agtcatgaac tgttagaaat cacacctgac gagtatgttc attttagcat
    10261 actagtggca ctcacttgga aacgtcggga atttccactt gagttccctg agtccaaaga
    10321 gtttgaaaaa ttaaaaaacc tctttatgta tccgattttg atggaacatt gccaaactta
    10381 cttagagcca catgccaaca tgacttttac tcaggaagaa ctggattata tctttttggt
    10441 ttattgttct gctaattctt cgttttccaa ggacaaatgg aatcaagaaa aaaagactca
    10501 tactattcaa ctgattcttc agcatacaag aggaaagcat ctactatcca agttcaagaa
    10561 tatcttagga aatgacattt cgaattctct ttctttttta acagcactga ctttcttaac
    10621 aagaacgttt ttgtttggtt tacaaaatct agttccctat tataattatt acgaacatta
    10681 tgggattgaa agcgacaagc cactgtatca tatttcgaaa gcaattgttc aagagtggat
    10741 gactgagcag aagattgaag gagttatcga ccagcatcgg ctgtaccttt tctcactcta
    10801 cttgacagaa accatctttt cctcactacc tgctatcccg atttttatca ttttaaataa
    10861 tcaagcagat gtaaacttaa taaagtccat tattttacgg aattttactg acaaagttgc
    10921 ctctgttaca ggatacaata ttctaattag tcctcctcct tcagaggagc atttgacaga
    10981 gccattgatt attattacaa cgaaagaata cctgccttac gttaaaaagc agtatcccaa
    11041 agggaaacat cactttttga cgattgcctt agatttgcat gttagccaac agcgtctcat
    11101 ctatcagaca attgtagata tccgaaaaga ggcttttgac aaacgggtcg caatgattgc
    11161 taaaaaggct cactatttgt tataagttca tcgtactgtc tacacacaaa aaggggcttc
    11221 ctaagccatc tctattctta tccccatatt tcccagtttt gggtaaatct gaacagaaaa
    11281 acacttctgc tctctagttt ctgctagtga acaaaagtgt tttttctggc tctataattt
    11341 ctgtagtggg taaatcccac tgtggagatt atagggcttt ttgagtatca aaaaagtccc
    11401 ataagactta taatgaaaag cgcctaaaca actcattaga aagtatctta tggaacacat
    11461 caatcatacc acattactca tcggaataaa agacaaaaac atcaccttaa ataaagccat
    11521 tcagcacgat acccatatcg aagtcttcgc tacacttgat tatcacccac ctaaatgtaa
    11581 acactgtaaa ggaaaacaaa tcaaatacga cttccaaaag ccttctaaaa tcccttttat
    11641 cgagattggt ggtttcccta gcctcattca tttgaaaaag agacgatttc aatgcaagtc
    11701 ctgtcggaaa gtcactgtag ctgaaacaac tctcgttcag aaaaattgcc aaatctcgga
    11761 aatggtgaga cagaaaattg cccaactcct actcaacaga gaggctctta cacatatcgc
    11821 ttctaaatta gccatctcta cctctacctc taccgtctat cgtaagctca agcaatttca
    11881 tttccaagag gattacacca ctttgcctga aatcctctcc tgggatgaat tctcctacca
    11941 gaaggggaaa ttggctttca ttgctcagga tttcaacact aagaaaatca tgaccattct
    12001 tgataacaga cgtcaaacaa ccatccgaaa tcatttcttc aagtactcga aagaagctag
    12061 aaaaaaagtt aaagtcgtca ctgttgatat gtctggaagt tatatccctc tcattaagaa
    12121 attatttccc aatgctaaaa ttgttctcga tcgtttccac attgtccaac acatgagcag
    12181 ggctcttaat cagactagaa tcaacatcat gaagcaattt gatgataaat ctctggaata
    12241 cagagctctt aaatattact ggaaatttat cctaaaagat agtcggaaac tctctcttaa
    12301 gcctttctat gctagaactt tcagagagac cttaactcct agggagtgtc tgaagaaaat
    12361 ctttactcta gtacctgaac ttaaagatta ctatgacctg tatcaactac tcctatttca
    12421 tctacaagag aagaatactg accagttttg gggcttaatt caagacacgt tacctcatct
    12481 caaccgcacc tttaaaacca ctttgagcac atttatttgc tataaaaact acatcactaa
    12541 cgccattgaa ttgccttatt ctaacgctaa acttgaggcc actaacaaac tcatcaaaga
    12601 catcaagcgc aatgcctttg gttttcggaa ctttgaaaac ttcaaaaaac ggattttcat
    12661 cgctctgaac atcaaaaaag aaaggacaaa atttgtcctt tctcgagctt agcttttctt
    12721 caacccacta cagttgacaa agagcccttt ttattattca agaacttgat tagctcaatg
    12781 catccaaggc gtcatccatt gaaagaactt cgtggaagac acgttgtgtc aattcagttt
    12841 tttgttctgg agtgaggtat ttagtgttta cacagtatcc agagatacgt acgataacgt
    12901 cttcgcctga catgattttt tcgtaaacat cgttcaagtc cataacgttc aagttaacgt
    12961 gttgtccacc gttttcgaag taaccatcaa ggattgttac caagttatca acttgttcat
    13021 cacgagtctt accaagagcg cgaggtgata cttgtgtagt caatgagata ccgtcagctg
    13081 cataactaaa gtcaaggcta gaaagtgagt tcaagttttg caaccaacca cctttagctt
    13141 tgttagatgg gttagcacct ggtgagaaga attcaagttt agacaagttc acagaaccat
    13201 cttcgttgag gtatacacct ttgtgaactg gtgagttacc agtttgttta gagtaagcaa
    13261 cgttagatgt gattgtcaaa agtgatactg tagcttctgc gtctttgtat agtttgtggc
    13321 tacgtagacg agttgtgtaa gcttcgatca accattctgc caattcgttt gaacgtgggt
    13381 catcttcacc ccagcgtggg tagtcaccga ttgtttcgta atcgtagatg tagccatctt
    13441 cgtcacggat tggtttaact gtagcgtatt tgatagctga caatgtatca acagtgttag
    13501 caaatccaca gataccgaat cccatgttgg cacgttgttt agttggcaag aaggccattt
    13561 gaacagcttc gtagttgtac ctatcagtca tgtagtggat gatgttcaag gcatctacgt
    13621 aagtgtcagt caaccagtca agagattttt caaagttcgc tttaactgat tcaaattcaa
    13681 gaacttcgtc acggattggt tcgatatcaa atactttgta gtctttgtga acatcgtcgt
    13741 aaccaccatt caaaccagta agaagggctt taagaacgtt tacacgagca ccgaagtact
    13801 ggatgttgtg gcgttgttct tcattttctg gatcaagtgg agacacacag catgagatac
    13861 agctcatttc accatatccg tctttagcca ttgttgttac accttcgtat tggatagaag
    13921 agtgtttgtg gctcatgtgc atacagtagc gacggaagtt gtatggcaat ttgtcagtcc
    13981 aaagaactgt caagtttggt tctggtgagt taccgatgtt gtcaagagtg ttcaagaaac
    14041 ggtagtccat cttagtaaca cggtgacgac cgtcgttacc cataccagcc atagaagttg
    14101 tgataaaggt tgggtcacct gagtacaatt ggtcataagc tttggtacga gcaaatttaa
    14161 ctgtacgaag tttcataacg aaatcatcaa cgaattcttg gatttctgat tcagtaaatg
    14221 taccacgagc aaggtcacgt tctgcaaaga tgtccaatac gattggtaca cgacctagag
    14281 atgtagcagc accgttaatc acacggcaga cagccatgaa agcaatgtta acccattgga
    14341 ttgcttcttt cacgttcatc gctggtttgc gaacatcaac cccgtaaagg tcacccaggc
    14401 gaacaacttg ttgcaatgct tggtattgaa ggtttacttc ttcacgaaga cggattgttt
    14461 cttcatcgat ttctttgatt gcattccagt catttacttt ttcttgcatc aagtagtctg
    14521 caccgtaaag agcaagacgt gcgtaaacac cgatgatacg tccgcgtgag tatgcatctg
    14581 gaagaccagt tacagtgtgt gcgtgacgag cgcgacgaat atttgaagtg taggcacgga
    14641 aaataccgtc gttaactgtt gttacatatt tagtgaagat ttcgtgaaca gctgggtctg
    14701 gttcgtatcc attttctttc aaagtagttt cagccatacg gataccacct tttggcatga
    14761 agttcaattt gaagagttca tcgttttgga taccgaagat aacttcattt tctttgtcga
    14821 taaatccagc agggatatca gcgatagatg ttggacgagt gtccattggg aaacgagttt
    14881 cttcgtagtg tgctttagtt tcttctacaa ttttcttgat gtgaagtgaa cgctctgttg
    14941 gtcctgcaag gaagctttcg tctccatcat aaggtgtgta gttagcttgt acaaagcgtg
    15001 atacacttgc tttttctttc caatctacgc ctttgaagcc ttcccaagct ttgtcaaaaa
    15061 tatcttgtgc ttcaacaact gtcttaacaa ccatattaat gtcctctttt ttctagtaac
    15121 agtcatctgt tacattcatg agacaagtat accatatagt aaccgatttc aacaagtgaa
    15181 aaatccctat ttttaaactt tcttttctaa aacagtctat attttatttc aaactgtatt
    15241 atatttttga aaaaataaag tccttttttc tttttttcag aaaaaagggt ataataaaag
    15301 aaaataagca gtaacactca atggaaatcg aaaagcaaac taggaagcta gccgcaggct
    15361 gctcaaagca ctgctttgag gttgtaaata gaactgacga agtcagctca aaacactgtt
    15421 ttgaggttgc agatagagct gacggggttt gaagagattt tcgaagagta taaaaaggtg
    15481 ctaggcatgt tgatttttcc tttgttaaat gatttgtcaa gaaaaatcat ccatattgac
    15541 atggatgcct tttttgctgc agtggaaatc agggataatc ctaaactcag aggaaaacct
    15601 gtcattattg gaagcgaccc tcggcaaaca ggtggacggg gagtcgtttc tacctgtagt
    15661 tatgaggcaa gagcttttgg tgtccattct gccatgagtt ccaaggaagc ttatgaacgt
    15721 tgtccccaag ccgtctttat ctcaggaaat tatgagaaat acaaagctgt gggactccag
    15781 attcgagcta tttttaagcg ctatacagat ttgattgaac ccatgagcat tgacgaagcc
    15841 tatttggatg tgacagaaaa taaacttggt atcaagtcag cggtcaaaat tgctcgcctc
    15901 attcaaaaag atatctggca agaactccat ctaactgctt ctgccggtat ttcctacaac
    15961 aagttcttag ctaaaatggc gagtgattat caaaaacctc atggtttgac agtgattcta
    16021 cctgaacagg ctgaggattt tctcaaacaa atggatattt ccaaatttca tggagtagga
    16081 aaaaagacag tagaacgtct tcatcaaatg ggcgttttta ctggtgctga tttacttgaa
    16141 gttcctgagg tgaccctaat agaccgtttt ggtagactag gctatgatct atatcgaaag
    16201 gctcgtggca ttcacaactc tccagtcaaa tccaatcgca tccgtaaatc aatcggcaag
    16261 gagaaaacct acgggaagat tctccgtgcc gaggaagata tcaaaaaaga gctgactctt
    16321 ctatcagaaa aagtcgctct caatctacat caacaagaaa aagctggaaa aattgtcatt
    16381 ttgaaaatcc gctacgagga cttttcaact cttaccaaac gaaaaagtct tgctcaaaaa
    16441 acacaagatg ctagtcagat aagccaaata gccctgcaac tctatgaaga attaagcgag
    16501 aaagaaagag gtgtccgcct attggggatt accatgactg gattttaaag ctcaatgaaa
    16561 atcaaagagc aaactaggag gctagccgca ggctgctcaa aacactgttt tgaggttgca
    16621 gataaagctg acgcggtttg aagagatttt ctaagagtat aaaaccttga agagttgccc
    16681 cttcaaggtt tttcttatac aaataaacgg acaaaactgt aaagtagcaa aacactacca
    16741 agcacgatac ggtatttacc aaaaagggtg aagtcgtgtt ttttcacata gctggtcaag
    16801 aagcgaatag ccaccatgct gaccgcaaaa gctactccca tcgcgaccaa gagcaaaaac
    16861 aattgcccaa agctcaagag ttctccggct ttcacaaatt tgaaaatctt taaggcacta
    16921 gctccaaaca taacgggaat cccaagatag aaggtaaatt ctgtcacaac tgaacgactg
    16981 gttccattta acaaaccacc gacaatcgtt gcacctgaac ggctagtccc tggtaaaaga
    17041 gcaagaactt ggaagagtcc gatatagaaa gcggtcgtat aaggaagctt gtccaactct
    17101 gttacacttg gctcgatagc acgcgcttta ttgcgctttt ccaaatagat gaaggcaacc
    17161 ccgtagataa tcaacatgag agcaactgaa accatgttat ggaagtgggt atcaaaccaa
    17221 tcatcaaatt taaagacacc aagtaaaggc aaagtggcaa tcaagacctt caaccatagt
    17281 ctccaagtct tacgaacttc ctgtttgtcc ttagtcggtt taaaaggatt gagcttgtta
    17341 aaataaatca ccataactgc taaaatagca ccaagctgaa ttacgacatt aaacatggac
    17401 ataaaggctt cattttgatt ttggtattgg ataaactcct ctgctaaaat caagtgacct
    17461 gtactggaaa tcggcaacca ttccgtaatt ccttcaacaa tcccgaagaa gatagatttt
    17521 aaaatttcaa taagatacat agatttctcc ttatattata tttaacgcag ttagctactg
    17581 ccaaagccca agtggtatac ttggaataag ccactgtgga ttagttcatt tcctccaatc
    17641 gcttgacgat ttccgaaagg gtctaaccac agctttttgt ttcaattggt aatgagtttg
    17701 ataacgcata gacgttttat ctcgtctaag gtaacaaggc aaaaagttcg tggataacca
    17761 agtagacttg aaatactata tctggaggta ctcccatgct ttatgtgggc attgatgtcg
    17821 ctaaaaataa acacgatgtt acagccttga atgttcaagg aaaaactgtt cttaaaccac
    17881 tcactttttc aaataataaa gctggttttg aactcttaga tctgtctttt cgacagctca
    17941 accaagactg tctcatcgct cttaaacttc tttctgaccc caatcgtgaa caatttcaac
    18001 acgataatcg gcaagtagaa ctaaaaatac tggctagaca tattcatcgt ctcaagaaaa
    18061 aacagtctga ttggaaagta caatacactc gttgtcttga tatcatcttt cctgagttgg
    18121 ataaaatcgt tggaaagcat tcagaatata cctaccaact cttgacacgc taccctaatc
    18181 ctcagaaaag gcttgaggca agatttgata agctgataga aattaagcga ttgaccgctt
    18241 ctaaaattca ggatatcctc tcaatcgcac ctcgttctat cggaacaaca tctcctgctc
    18301 gtgaattcga aatcatcgaa atcatcaaac attacaagag gctcattgac aaggcggaaa
    18361 catgtgtcaa tgacttgatg gctgagttca actcggtcat cacgacggtt actgggattg
    18421 ggggtcgttt aggggcggtc attttagccg agattcgaaa tattcatgcc tttgataatc
    18481 ctgctcaatt acaagctttc gctggactgg attcttctat ttatcagtca ggtcagattg
    18541 atttagctgg aagaatgatc aaacggggtt cccctcatct gcggtgggca ctcatacaag
    18601 ctgccaaagc atgcgctcgc ttttcacctg cttttaaggc ctatcttaag actaagttag
    18661 aataaggaaa acattacaat gtagccatca tccaccttgc aaaaaaactt atccgaaccc
    18721 tgttttatat cctaaaaaag agctgccatt tgacgaacaa aaagtgatgt aatttctgaa
    18781 attaacacag gattaccttt gaaaaaatgg actttttcaa gggctttttg ccgtgctcta
    18841 aaatcatcgc caaatcatca aattgaaata agaaatagtt tagataaaac tattgacttt
    18901 tcttatagtt tgtctttctt ctatcttcca ttatatcata ctttttcagt ctatggtagc
    18961 tctctttaaa aggctccgat actgccgcca cctccgcctc cagagaagcc accgccagaa
    19021 cttccacttc cagaagatac ggagtaggta cttgctgtat ttgcgacact agcataatgg
    19081 ctcatttgcg cgcttgaatg ataaaacata ctgtgccagc cataagctac atagagattg
    19141 atatctggat tttcaacttg aatctgatga accttcatca aatgactaac cttgtccgca
    19201 tagccaaata aggttgcata gaccaagaga cgattccaaa caacaatact ttccaattca
    19261 gccttatcca gtcgtgcaat ctcacgtaac atattttcaa aactggtcca gagatagtag
    19321 acctcagctc ccgcttcatt tagaacacca tcacgattat ctagtcgaag cttccaataa
    19381 tagaaaacag acaaaactaa ccctagaaaa ccaagtattg gcaaagggag gtaaagatag
    19441 ccatgaacgt ctaaactgta caagaacaaa ccaaatccga taaatagggg caggatagtc
    19501 aaggcaccca tacccacttg caaggccttt tccccaccag ttaaaggacg ataataatct
    19561 gggagccccc agaaggaaac tcgttttctc actccttctt gcatctggtt caatacctct
    19621 tcaaaagaag atttgagttg aagccctctt gcttgaatcc gtttttcatc agaaactttg
    19681 gctctacgat aaagactatc agataccttg taatccgcaa acaaattgga aagagtttct
    19741 tcttttttac ctgaaaaagc tagatttagg cagtctctct caaagcttga caaaccatct
    19801 tcttttacta gcctcaaacc aactgcatct ccttctgaaa taatagaaac attcccacgg
    19861 tccatcacat ctagcaaggt agcttgaata agttggtcaa aagtgaattt gccagccccc
    19921 ttgactaagg gactcacttc ctccaaggag gtcgagtaga cagcctctga taaaaccata
    19981 ggctctaatt ccattggtgg ttcatagaga cgatgatttt tggcatattt gactgaagga
    20041 gtggtctttc ttctataaat aaaatagaag cagacactca ataacaagga gatagaaagg
    20101 atcgaaggga ggacccaagt aacaagttgt ttactctgat ctttttctct aacaatcgag
    20161 tcttctatct tattaaactc ttctaaacga ttccctttca atccctgatc cctagcgcta
    20221 gcaaaatcgg tccgaggcca gtaggcatgc aactcaactc cacgcttagc cggaagattg
    20281 tctaaacgga tagtataatc aaggttactc ttttcaatcg ttccctctct aaaaagtttc
    20341 cctgtatgga aaaagagttt ttcagccccc ttgtctcccc ttacatgaaa ttcaaacttt
    20401 tcaatagact ctgaactatc tgtcagaggt tgccaattta attcagcgat atcatcataa
    20461 aggaaaagta aattttttaa gttccagacg aggtcaactt caactatgtc gccctcctga
    20521 cctggattat agactctcac agtataacca tccgcttctt ctgttacttc gctagtcaca
    20581 tctgctagtt ctgcaccgtt tttcgcggcc tgaacctttg gatgagggtc aatgtcaaac
    20641 ccgctaggca tcttaccagc acgtccaagt cccacgattt gtcccttaaa gtcctcctca
    20701 aactggtaaa ctatcttctg tctaaactct gccgtattat ctgcatgaat atacaaatcc
    20761 ccttgataag agtttatctt gaaatcaatg gcaaaaacag agagtggaag aaggcaaaac
    20821 aagcctaaca ccagtaagaa aaaagttttt ttcatcaact aagccccctt tttatctttc
    20881 ttatcattat agcatttttt cgtaagtaaa ggcttactta tgttgaaaaa ttacgcattt
    20941 ttcgataaaa taggagacag ttatttttta atagatcaga ataggagaaa tcatgagaaa
    21001 aatatactta tctattttca caagtctctt gctgatgcta ggacttgtca atgttgctca
    21061 agccgatgaa tatttacgca tcgggatgga agcagcatat gctcccttta actggaccca
    21121 ggattatgat agcaacggag ctgtcaaaat cgatgggacc aatcagtatg ccaacggata
    21181 cgatgttcaa atcgccaaga aaatcgctaa ggacttaggt aaagaacctt tggttgttaa
    21241 aaccaagtgg gaaggtctag tccctgccct tacttctggt aagattgaca tgattatcgc
    21301 aggtatgagt ccaactgcag aacgcaaaca agaaattgcc ttttcgagca gttactacac
    21361 tagcgaacca gttttgcttg tcaaaaaaga ttctgcctac gcaagtgcta aatctttgga
    21421 tgactttaac ggtgcaaaaa tcacttctca acaaggggtc tacctctacg acttgattgc
    21481 acaaatccca ggtgctaaaa aagaaacagc catgggagac ttcgctcaaa tgcgacaagc
    21541 tcttgaggct ggtgtcattg atgcttatgt ttctgaacgt ccagaagcac tgactgctga
    21601 agctgcgaac tctaagttca agatgattca agtagaacct ggtttcaaaa ctggggaaga
    21661 agatacagct atcgctatcg ggcttcgtaa aaatgacaat cgtattagcc aaatcaatgc
    21721 cagcattgaa accatttcaa aagatgacca agttgccttg atggatcgta tgatcaagga
    21781 acaacctgcc gaagctacaa caactgaaga gactagcagt agtttcttta gccaagtcgc
    21841 taaaattctt tctgaaaact ggcaacaact cttgcgtggt gctggtatca ctcttttaat
    21901 ctctatcgtc ggaaccatca taggtctcat tattggactt gccattggtg tcttccgtac
    21961 tgctcctctc tctgaaaaca aagccattta tggccttcaa aaactagtcg gctgggttct
    22021 caatgtctac attgaaattt tccgtggtac gccaatgatt gttcaatcga tggttatcta
    22081 ctatggaact gcccaagctt tcgggatcaa ccttgaccgt acactggctg ctatcttcat
    22141 cgtttcaatc aataccggtg cctacatgac tgaaatcgtc cgtggtggta tcctagcagt
    22201 tgacaaggga caatttgaag ctgcgactgc tcttggtatg acccataacc agaccatgcg
    22261 taagattgtc ctacctcagg tagtccgtaa catcctacct gcaactggta atgaatttgt
    22321 catcaatatc aaagatacat ctgtattgaa cgttatctct gttgtcgaac tttatttctc
    22381 aggaaatacc gtggcaacac aaacctatca atacttccag acatttacaa tcatcgccgt
    22441 gatttacttt gtcctcacct tcaccgtaac acgtatccta cgctttatcg agcgcagaat
    22501 ggacatggat acctacacta caggtgctaa ccaaatgcaa acggaggatt tgaaataatg
    22561 acacaagcaa tccttgaaat taaacacctc aaaaaatcct atggacaaaa cgaagtgcta
    22621 aaagacattt cactcactgt ccacaaggga gaggtcatct ctatcatcgg aagctctgga
    22681 agcggaaaat cgaccttcct acgctccatt aacctacttg aaacaccaac tgatggacaa
    22741 atcctttatc atggacaaaa cgtcctcgaa aaaggctatg acctcacgca ataccgtgaa
    22801 aagttgggga tggttttcca atcctttaac ctctttgaaa atctcaatgt tcttgaaaac
    22861 acaatcgtcg ctcagacaac tgtcctaaaa cgcgaacgca cagaagctga aaagattgcc
    22921 aaagaaaacc tggaaaaggt cggcatggga gaacgctact ggcaagccaa accaaaacaa
    22981 ctctcaggtg gtcaaaaaca acgtgtggcc atcgctcgtg ccctctccat gaatccggac
    23041 gccattctct ttgatgaacc aacatcagct ctcgatccag aaatggttgg agaagtcctc
    23101 aaaatcatgc aggacctggc tcaggaaggc ttgaccatga ttgtcgtaac ccatgaaatg
    23161 gaatttgccc gtgatgtctc tcaccgtgtt atctttatgg ataagggcgt gatcgctgaa
    23221 gaaggtaaac cagaagacct cttcaccaat cctaaagaag accgaacaaa agagttcctt
    23281 caacgctatc tcaaataaaa agaaaaggct gcatcaaccg tgcagtcttt ttgctgtcct
    23341 caaaatgaaa aggcagattc tctatctcta ctacttgaag gtcaagaatc cgccgttatc
    23401 caaagattaa tcttcaaatt tttcataatt tttttcatag aaatcaatta ggcctagggc
    23461 tgtttcaaat gaaatatttt ttacttttgc acgaccctgc gccagagcaa tgatagacat
    23521 ttcacgcgca ttcgtttctt tagagatacg gtagcctgtg attttcttat cacgaaccca
    23581 gccaacaact gattctactt tttcaaagtt tgacttagcc atgtttttct cctattttct
    23641 tctttataat atttaattgt atacgttttt actacttttg tcaataaaaa aaacatatat
    23701 tcaacgaaaa taattagttc agaattttct tacttccttt ttaaatccga taatatatag
    23761 gttttgctag cctctacacc ataaatattt gctaataaaa ctactgtatt attaccctct
    23821 taaggtgcga aattattcaa gttcttaaaa aatgcttctc tatttccgta agatagctta
    23881 tttcttcgat ttaagaactg aagatgatag ttctaacctt tagaaatcca agccttcact
    23941 agctcaaaaa ctcctatctt tcttcctcaa taaatcatct gagagatagg tattccttat
    24001 atccttcaaa ttcatcactc ctttggatat tgaggtgcta gcctagaagc agacacccga
    24061 ttatctaaac catccttaat agagatgaca agacagataa gctcagttaa ttacttatat
    24121 atctttttaa tatggtatat ttgtcaacaa aaagaaatca aatcatacct tatactcaat
    24181 gaaaatcaaa gagcaaacta ggaagctagc cgcaagttgc tcaaaacact gttttgaggt
    24241 tgcagataga gctaacgtgg tttgaagaga ttttcgaaga gtattaaaga cagtgtgact
    24301 atgcttgtca atagatagga aatcaaaatg aaggatggaa atctgagcca aacatcataa
    24361 gtgctataat gaacagaagt aagaattgca cgataagttt tctaaaacca taggaatcgt
    24421 cccctttctt catcttcatt atagcacata tacatcagtt gtacaaataa tatgatattt
    24481 ttttattagt cctcagacaa gcatattata aagcgtttca ttaccattta agttaatata
    24541 agctggatca aaaccttcca ttctacgaat caaacctgca taatcatgct tatctgctaa
    24601 agcgatccca attaatactg ggcctgttcc cttgctagct cgtttgatat actcaaaacg
    24661 tgtgatatca tcatttggcc ccaggatatc atttacaaac tcacgcaaag ctcctggacg
    24721 ttgtgggaaa ttgaccacaa agtaatgttt gataccatca taaatcaagg cacgctcttc
    24781 catttctggc atacggttga tatcattatt tcctccagaa atgatacaac aaatggtttt
    24841 ccccttaata tattcagcta aaacctctaa agaggcgata ctagccgctc cagcaggttc
    24901 tgcgactatc ccttgcttag agtaaaggtc aatcaaggtt tcagaaatca atccctcatc
    24961 gacacctacc aaagttttaa tatgttgacg agttgcttca taggtcaact gacctacctt
    25021 ttgcacagca atcccatccg caaatttatc aatttccttg agtttgactg gacctccagc
    25081 ctcaaaggca gctttcatgg aacgcgctcc attcgcctct actccgataa cctcaatctc
    25141 tggacttgtt tccttgatat aggtagaaac cccggcaatg agaccgccac caccaacagg
    25201 aaccaagaca gcatcaaaat caatcgattc ttttcgagct tcttctaaaa tctcataagc
    25261 aactgttcct tgacctgctt gaacatgagc atcatcaaaa ggatcaataa aggtacgatt
    25321 ttcagagact gtaaattctt gagctgcttt ggctgaggca tcaaaggtat ctccaactag
    25381 tttaatagtt acaaaatccc caccaaaaaa gcgaacctga ccaatctttt gttgtggcgt
    25441 agtaataggc ataaagatag tagcaggaat tttcatttca ttacaagtat aggctactcc
    25501 ctgcgcatga tttcccgcag aagcgcagac taccccacgt tcacgttctt ccttgctgag
    25561 ctgggaaatg gcataatagg caccacgaat tttaaaggag cgaacacgct gggcattttc
    25621 ttttttcaaa taaatcttag caccatactt ctccgataaa taatgatcgt aatccagtgg
    25681 agtattcaca accacaccgt tcaagacctt gtgagccttg attatatctt ttgaacttaa
    25741 catataaaac ctctttttct ataaaaaaca gtcactaatg actgtttttt agttattcat
    25801 ctccgaaaac ttcagtaaca ctttcatggt atttatgagc catacgaatc gaaaactctt
    25861 taggaagttc ataacgattt gtggaaatcc aatcatataa ccattctacc aaactttctt
    25921 cactatcatt acgatggaag ataaaatagt ttaaaatttc tttatattct acatcattca
    25981 aatccaacgt gtctacaaat tgactacgag gaacaaaatt agaatctaat tttcttagtt
    26041 gatctgtcaa ttctcccaat tgtaaatcca actgaaaaaa tagtttttgc agttgcctat
    26101 cagtttcatc acatcctgtc ttgatagaaa acaaattggt aatattcata tgatttcaac
    26161 ccctaaataa gtacatctaa tatcccacga atagctgaag ctaaagtttt cgcagtccag
    26221 tcatttaaac ccgattcttt caatccagat gcaataattt gctctatttg atataaaccg
    26281 ccatctatcg tctcatttat tctgcgaaga ggaccttcaa tataggataa agcttctccg
    26341 aatctaacag ctgatttagg tcctaatgat ttaccaacta tatttgttaa tgttttttat
    26401 ttctcaaaat ccatttcgct atataacgag cagatttagt cgcaccagct ctctcaaacg
    26461 gagaatgaat ttcaagacct tcttctctag ctatttgtgc caatttgaag aattgttcaa
    26521 aggtcatatg caacctacca tcttcaaaat tagcatcatc ataaatgtta attacagcat
    26581 tttcatcata cgaccaatct gctttatttt ggtctgctag cactattacc gacggtgtaa
    26641 ttacattata caactagaac caataataac gatgcaattt ttctcataat ctttttcata
    26701 aaatcatctc cagcgctata tatttctaat tagttataga ttttgaatgc atcatcgtcg
    26761 tttttaccaa cgaatggcat tgctttacgc aattctgcac caactttttc aatttcaagg
    26821 ttagctgctt gttcacggta agcagtcaat tttggacgtc cagctttata gtcatttaca
    26881 aagtcatttg caaatttacc attttggatg tctgccaaga cagccttcat attttcttta
    26941 acttgttcag tgattacacg tggacctgat acatagtcac cgtattcagc agtgtttgaa
    27001 atagattgac gcattttctt gaatccacct tcatagatca agtcaacgat caatttcatt
    27061 tcgtgaagaa cttcaaagta agccaattct ggagcgtaac ctgcttctgt caagacttcg
    27121 aaacctgctt cgataagggc agtcaaacca ccacaaagta cagcttgttc accaaacaaa
    27181 tcttcttcag tttcttcttt gtaagttgtt tcaagaagac ctacacgagc cgctccaaca
    27241 cctttacacc agtccatagc aatgttttta gcatttcctg ttgcatcttg gtatactgca
    27301 taaagagctg gaacaccaaa tccttcttcg taagtacgac gtaccaagtg tcctggtcct
    27361 ttaggagcac acatgaagac atctacatcc gcaggaactt tgataaattc aaagtggatg
    27421 ttgaaaccat gggcaaatcc aactgcgttt ccagcttcca agtttggagc gatttctgct
    27481 tcgtacaatt cttgttgaat ttcgtctggc gccaagatca tgataacatc agccaactta
    27541 gtagcttctg ctactgtgta agtatcaaat ccatcttctt ttgctttatc aaaagattta
    27601 cctggacgta cacctataat aacgtcacga cctgaatcac gcaagttttg agcatgcgca
    27661 tgcccttgtg aaccataacc gataacggcg atttttttac cgtcaagtgc tgctacttta
    27721 acatcttttt catattccat ttgaactgtc atagcttttc tctcttttct attatttatt
    27781 gccttttagg ctggtttaat aaatttaagt tggattttta atcgcgggta aatccagttg
    27841 cacccgttcg agcaatattg cgaataccgt atgggcgaat gactctcaat agggcttcgc
    27901 tcttttctgc atttcccgtc atctgaatgg taatcgagct tggcgctacg tctaccactg
    27961 ttgcacggaa aggttgaata atcgctaaaa tctcagctct cttctcagct ggcgctgaca
    28021 tcttaaccaa aatcacctcg cgctccaaat gaggcttgtc tgtaatatct cgaatgcgaa
    28081 tcacatcaat ctgacgattg agctgtttga tgatttgctc cacttcatca tgagaagcaa
    28141 catcaataat aatagtgata cgcgatacat tcggatcttc tgttgctcca acagagatgc
    28201 tttcaatatt aacctgacga cgagatagga cacctgtaaa gcgattgagg actcctgaac
    28261 gattttgtag ttttgctgtt aacattctac gcatggaact gcacccccaa catctcatga
    28321 ttactcttac cagccggtac cattggtaac acctgttcct tacgagaaat atctacctca
    28381 attagcatag gaacatcctc agtgatgact tcaaggtctt gagccaaggt ctcaggattg
    28441 tcaaacttat agtttttaat gccataagcc tgcgccatca attggaaatc aggaagggta
    28501 tcaaagaccg actctgatgt tctgccttca tagaaggatt cctgccactg gcgaaccatt
    28561 ccgagtgaat gattgttcag cataaccacc ttgattggca ccttgtaaat attcaaaata
    28621 gccaactcct ggttagtcat ttggaaacca ccatccccaa caaacaagac tacttcctta
    28681 tctgggttag caattttagc accgattgct gctggaattc caaagcccat tgttcccaaa
    28741 ccacctgaag tcactaactg acgttcattt tggtagggat aatactgagc tgtccacatt
    28801 tggtgttgac caacgtctgt taccacaatg gcatctccat tcgtcaattc accaattcgt
    28861 tcaataactg cttgcggttg aaccacacgc tctttcttgt cataagaacg aacacgattc
    28921 ttgtctttag tgactttctc aatccacttt tcagtattgt tgtgaactgt tggttctgct
    28981 agcaacattt gcaaggcctt cttagcatct ccaactacag gaatgtctgc actgataatc
    29041 ttgccaatct cagctgggtc aatatcaatg tgggcaacct tagcattctt agcgaaagtc
    29101 ttaggattcc ccgtcaaacg gtcatcgaaa cgagaaccaa tactaatcat aaagtccgct
    29161 tccgtcatgg caatatttgc tgcgaatgac ccgtgcatgc ctcccattcc aagaaagagt
    29221 gggtgactcg ttgcaatcgt tccttgtccc aaaagactgg ttaccactgg aatttgatag
    29281 cgttctgcaa attcatttag ttccgtagca gcctcagcat aactaattcc accaccagct
    29341 aacaagactg gctttttagc cttggacaat tgcttcaaga ttttcttgat ttgcatatca
    29401 ttcggctcaa gagtcggctg ataacttggt aaattcactt ctggtgaata aatgaagtct
    29461 gtttctaaag cagatatgtc ttttggtagg tcaattacaa ctggccctgg acggcctgta
    29521 gttgcgatat ggacagcttc cgtaatgata cgcggaatat cagctgtctc acgaacttgg
    29581 taattgtact tagtgattgg catggtaatt cctacgatgt ctgcctcctg aaaggcatcc
    29641 ttcccaatcc ctgctcgcgc cacctgacct gtaaagacca aaaggggaac gctatcgctc
    29701 atagcatccg caatccctgt aatggcattt gttgctcctg gtccactagt gacgacggca
    29761 acacccaact ttccagttga tttggcataa ccttcagctt catgcaaaca accttgctca
    29821 tggcgcccta gaatgtggcg aatgccttta aaattatata tcgcatcata aaaaggcaaa
    29881 accgcaccac caggataacc aaagatggta tcaactccta aatcacgaag tgtttccaaa
    29941 actaggtccg accccgtctt aggagattct aaactgattt tctccattgt tcccctttct
    30001 ttcctcttaa aaataacttg ttactatcat accatttttt caaaattttt caagataaaa
    30061 gaagaaattt tctgaatttt ctattttaac gtttatttat gaatgttatt tttgttttta
    30121 ttaaaaagat accgatttca tttactaaaa aagaaaaaag aactgatttc tcagtccttc
    30181 attaatctta ttccacacta aataggtatg ggtaaacagg ttgttgacct tggtgaatct
    30241 cgacttcaac gtcttcgaat tcttctacga tttcttgagc gatttcattg gcaagttctt
    30301 cgcttccgtc ttcaccgaca tagaaggtta cgatttcact gtcttcatcc aacatatgtt
    30361 tcaaggtttc agtcaatgtt tggtgcatat cagggtttga cacaagaatt tttccatcca
    30421 ccatacctag attatcgttt tcatggattt ctaagccatc gatcgttgta tcacgcacgg
    30481 ctgttgtgac gcttccgcta acgacatctc taagagcagc tgtcatacgc tcttggtttt
    30541 cttcaatgga cttgcttgga tcaaaggcaa gaagacttgt cataccttga ggaagagtgc
    30601 gagcctctac cactactgct ggttgctcca aaacttctgc cgcagattga gctgccatga
    30661 agatgttctt gttgtttggc aagaagatga tgttacgggc attgacctgt tcaacagcct
    30721 tgataaagtc ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca taatccacgc
    30781 cttgagaaca gaagatatct gctagacctt taccagccac cacagcaatc aaagcatact
    30841 ctttttcttc agccgacttg ataacttgag tagcttcttt ctcaacctgt gcttcgtgtt
    30901 ggttacgcat attgtcaact tttaccttga ccaagctacc atatttgaga ccttcttgca
    30961 taacaagtcc tggatcttct gtatgaacat ggactttgac aatttcatca tcgttaacaa
    31021 cgaggagaga atccccaagc tcatccaagt agttacggaa ttcatcgtag tcaaaatctt
    31081 tagcataggt tggaccttgc ttaagagcta ccatgatttc agtacagtaa ccaaacgtga
    31141 tgtcctcagt cgctacgtga ccagctacag acttatgatg ctctacattg atcatctcac
    31201 tcatgttggc aggagtcgct acaaagtcct cagatgcaat atattcgcca gtaagggctg
    31261 aaaggaaacc ttcgtagatg aagaccaatc cttgaccacc tgagtccaca acgccaactt
    31321 ctttcaatac tggaagcatg tctggtgttt tagctagagc tgttttagca ccttccaagg
    31381 ctgcgcgcat gacttcaaca gtatcatctg tttgctcagc ttttttctta gcaccgatag
    31441 cagctccacg agaaactgtc aaaatcgttc cttcaacagg tttcatcact gccttatagg
    31501 caacttccac acctgattgg aaggccagag ccaagtcttg acctgttaac tcgtctttat
    31561 ccttgatagc ttgggaaaat ccacggaaaa gctgagacgt aatcactcct gagttcccac
    31621 gcgcacccat caaaagccct ttagcaagaa tgctcgctac ttctccaact gtagaagctg
    31681 gcttgtctgc aacttcttta gcaccatttt caatggtcat tcccatattt gtcccagtat
    31741 ctccatctgg aactggaaag acgtttaatg aattgacata ttcagcttgc ttattcaagc
    31801 gagttgatgc agcctgcacc atttcttgaa ataagctagt agtaattttt gacacggtta
    31861 ttctcctaca actttgatat tttgaatgta gacatttaca gtctgagcag taattccaag
    31921 ctggttttcc aagctaaagg caacacgctc ttgaatgttt tttgacactt cactaatctt
    31981 tgttccgtag cttaacacgg tatatacatc aactgcaata ctgccatctt cggctgcctt
    32041 tacgacgaca cctttagaat aattttcctt acctagcagg gcttggaaat tatctttgag
    32101 ggcattttta ctagccatac cgaccacacc aaaaatctca gttgctgctc cacctacgac
    32161 ggttgcaatc acttcatctg ttagttcgat ttgaccatct tttgtattaa tttttacagt
    32221 catccttttt acctcaacta gttgatactc tattttatca tatttcagcc caagtgtaaa
    32281 agcagaatga tgtatcagcg gatatttact ctatttttca aacgatgtta tacccacaat
    32341 aaaagaaaaa agaccctaag gtctcctttg cttttattat taaacgcgtt caactttacc
    32401 tgatttcaaa gcacgagctg aagcccaaac ttttttaggt ttaccatcga taagaacagt
    32461 aactttttga aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt gtgaacggtt
    32521 gtttcctgat acagtcttac gacctgtaaa gtaacatact ttagccattg tgttttcctc
    32581 ctattagatc taatatagcg gatgtgctag caccacatac cgtactatgt tatcacactt
    32641 tcttgttttt tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc aggtcttgcg
    32701 tgacattttc tgctctccac atgccattgt tgattaacag aacaccagaa ttaaaattat
    32761 gtgtataaaa atcatctcta actgcagcta agggtatagc cgtcaagtcc aaatcccaca
    32821 gctcatctat cgattttctt acaacaatat ctaaatccaa atacagtaca cgagactcgc
    32881 ttacatactt tggaataaaa tacctaaaaa agccgcatat gaaagtccct caaaggggag
    32941 acgataacct ttcagaatac tactgtcaat ctaaacattc acaatctcac tattcaaagt
    33001 ctctagtctt ttttccatca attggaacca ttctcgcgga aggtcatcat taaaaacata
    33061 aaacttaaga ttataataga tgaacacaaa gagattttat tgttgtttca actttatcca
    33121 tataagcatt atctgcacct aagacaatcg cttttttctc ttctttcact ctttatctca
    33181 tttcttttta ttcccatcat atgtttctac gtaaccatta ttttcgccca ttcgttcgta
    33241 aaaccatacc agtggagatt ttagatgaag tcccattacg gtttacaatt tttacattac
    33301 gacacggagt tttacaaatc gatttcattt gccaaacgta gttagtaagg cagttagcta
    33361 gttcgccaaa tagcgactag cgtccaacaa tttggaactt tagttccaat tgttggtact
    33421 gagtcacatc ttctcctcta actctacgtc tggatacttg tccgcaaacc agcggagggc
    33481 aaagtcattt tcaaagagaa agactggttg gtcaaaacgg tctttggcta agatattgcg
    33541 acttgacgac atccgttcat ccaagtcctc aggcttgatc caacgaacgg tctttttacc
    33601 cattgggctc atgaccactt ccgcattgta ttcgccttcc atacggtgtt taaagacttc
    33661 aaactggagt tgaccaacag ctcccagcat gtactcacct gtttggtaat tcttataaag
    33721 ctgaacggct ccttcttgca ccaattgctc aatccccttg tggaaggatt tttgcttcat
    33781 aacattctta gcagaaactt tcatgaaaat ttcaggagta aaggttggca gtggttcaaa
    33841 ttcaaacttg ttttttccaa ccgtcaaggt atccccaacc tgataagtac cggtatcgta
    33901 aaccccgata atatcacctg atacggcatt ggtcacattc tcacgactct ccgccataaa
    33961 ctgggtaaca ttagatagtt tggcaccctt accagtacga gggagattga cactcatgcc
    34021 acgctcaaat tcgcctgata cgatacggac aaaggcaata cggtcacggt gacgaggatc
    34081 catgttggct tggattttaa agacaaagcc tgagaaatcc ttgtcataag gatccacaat
    34141 ttcaccgtct gttttcttgt gaccatgtgg ttctggagca aacttgagga agatttcaag
    34201 gaaggtctgc acaccaaagt ttgtcagggc tgaaccgaaa aagacaggcg tcaattctcc
    34261 agccagaata gcttcctctg aaaactcatt cccagcttca tttaaaagct caatgtcatc
    34321 cttgacttgc tcgtagaaag gattgctacc aaagagtttg tccccgtctt ctagactggc
    34381 aaaacgctca tcccctttgt aaagctctaa acgttggtta tagaggtcat acaagccctc
    34441 aaaggctttc cccatcccga taggccagtt catagggtag ctagcaatgc ccaagatttc
    34501 ttccaattct tgcaagagat ccaaaggctc acgaccgtca cggtccagct tgttcataaa
    34561 ggtaaaaact ggaatgccac gatgtttcac aacctcaaac aatttcttgg tttgagcctc
    34621 gatccccttg gcagagtcca cgaccatgac cgcagcatcc accgccatca aggtacgata
    34681 ggtatcttct gagaagtcct cgtgccctgg cgtgtctaag atattcacgc gcttgccgtc
    34741 gtagtcaaat tgcataacag atgaagtaac agaaatccca cgttgcttct cgatatccat
    34801 ccagtcagat ttagcaaaag tccctgtttt cttccctttt accgtaccag cctcacgaat
    34861 ctcaccccca aagtagagta actgctcagt gatggttgtt ttccccgcgt ccgggtggga
    34921 gataatggca aaggtacgac gtttcttaat ttcttcttga atattcataa gttctctttc
    34981 tttgattctc tatttttctt gtttcaatag ctgagaatga tttttacatt ggattttacc
    35041 attcctttca acattccatt atatcggatt ttagcatttt tttcaatttc tatttctttt
    35101 cacttccccc tcccttattt ataggaaaat atggtaaaat agaacagact aaaaatcatc
    35161 atttcacgaa aggatgcaag atgaaaatta cgcaagaaga ggtaacacac gttgccaatc
    35221 tttcaaaatt aagattctct gaagaagaaa ctgctgcctt tgcgaccacc ttgtctaaga
    35281 ttgttgacat ggttgaattg ctgggcgaag ttgacacaac tggtgtcgca cctactacga
    35341 ctatggctga ccgcaagact gtactccgcc ctgatgtggc cgaagaagga acagaccgtg
    35401 atcgcttgtt taaaaacgta cctgaacaag acaactacta tatcaaggtg ccagctatcc
    35461 tagacgatgg aggagatgcc taatgacttt taacaataaa actattgaag agttgcacaa
    35521 tctccttgtc tctaaggaaa tttctgcaac agaattgacc caagcaacac ttgaaaatat
    35581 caagtctcgt gaggaagccc tcaattcatt tgtcaccatc gctgaggagc aagctcttgt
    35641 tcaagctaaa gccattgatg aagctggaat tgatgctaac aatgtccttt caggaattcc
    35701 acttgctgtt aaggataaca tctctacaga cggtattctc acaactgctg cctcaaaaat
    35761 gctctacaac tatgagccaa tctttgatgc gacagctgtt gccaatgcaa aaaccaaagg
    35821 catgattgtc gttggaaaga ccaacatgga cgaatttgct atgggtggtt ccggtgaaac
    35881 ttcacactac ggagcaacta aaaacgcttg ggaccacagc aaggttcctg gtgggtcatc
    35941 aagtggttct gccgcagctg tagcctcagg acaagttcgc ttgtcacttg gttctgatac
    36001 tggtggttcc atccgccaac ctgctgcctt caacggaatc gttggtctca aaccaaccta
    36061 cggaacagtt tcacgtttcg gtctcattgc ctttggtagc tcattagacc agattggacc
    36121 ttttgctcct actgttaagg aaaatgccct cttgctcaac gctattgcca gcgaagatac
    36181 taaagactct acttctgctc ctgtccgcat cgccgacttt acttcaaaaa tcggccaaga
    36241 cattaagggc atgaaaattg ctttgcctaa ggaataccta ggcgaaggaa ttgatccaga
    36301 ggttaaggaa acaatcttaa acgcggccaa acactttgaa aaattgggtg ctatcgtcga
    36361 agaagtcagc cttcctcact ctaaatacgg tgttgccgtt tattacatca tcgcttcatc
    36421 agaagcttca tcaaacttgc aacgttttga cggtatccgt tacggctacc gcgcagaaga
    36481 tgcgactaat cttgatgaaa tctatgtaaa cagccgtagc caaggttttg gtgaagaagt
    36541 gaagcgccgt atcatgctgg gtactttcag tctttcatca ggttactacg atgcctacta
    36601 caagaaggct ggacaggtcc gtacacttat cattcaagat ttcgaaaaag tcttcgcgga
    36661 ttacgatttg attttgggtc caactgctcc aagtgttgcc tatgacttgg attctctcaa
    36721 ccatgaccca gttgccatgt acttagccga cctcttgacc atacctgtaa acttggcagg
    36781 actgcctgga atttcgattc ctgctggatt ctctcaaggt ctacctgtcg gactccaatt
    36841 gattggtccc aagtactctg aggaaaccat ttaccaagct gctgctgctt ttgaagcaac
    36901 aacagactac cacaaacaac aacccgtgat ttttggaggt gacaactaat gaactttgaa
    36961 acagtcatcg gacttgaagt ccacgtagag ctcaacacca attcaaaaat cttctcacct
    37021 acttctgccc actttggaaa tgaccaaaat gccaacacta acgtgattga ctggtctttc
    37081 ccaggagttc taccagttct caataaaggg gttgttgatg ccggtatcaa ggctgctctt
    37141 gccctcaaca tggacctcca caaaaaaatg cactttgacc gcaagaacta cttctaccct
    37201 gataatccca aagcctacca aatttctcag tttgatgagc caatcggtta taacggctgg
    37261 attgaagtcg agctagaaga cggtacgacc aagaaaattg gtatcgaacg cgcccactta
    37321 gaggaagacg ctggtaaaaa cacccacggt acagacggct actcttacgt tgaccttaac
    37381 cgccaagggg tacctttgat tgagattgta tctgaagccg atatgcgttc gccagaggag
    37441 gcctatgctt atctgacagc cctcaaggaa gttatccagt acgctggcat ttctgacgtt
    37501 aagatggaag aaggttctat gcgtgtggat gccaacatct cccttcgccc ttatggtcaa
    37561 gaaaaattcg gtaccaagac tgaattgaag aacctcaact ccttctcaaa cgttcgtaaa
    37621 ggtcttgaat acgaagtcca acgccaggct gaaattcttc gctcaggtgg tcaaatccgc
    37681 caagaaacac gccgttacga tgaagctaac aaaacaacca tcctcatgcg tgtcaaggaa
    37741 ggggctgctg actaccgcta cttcccagaa ccagacctac ccctctttga aatttctgac
    37801 gagtggattg aggaaatgcg gactgagttg ccagagtttc caaaagaacg tcgtgcgcgt
    37861 tatgtatctg accttggttt atcagactac gatgctagtc agttgactgc taataaagtc
    37921 acttctgact tctttgaaaa agctgttgcc ctaggtggtg atgccaaaca agtctctaac
    37981 tggctccaag gggaagtcgc tcagttcttg aatgctgaag gtaaaacact ggaacaaatc
    38041 gaattgacac cagaaaactt ggttgaaatg attaccatca tcgaagacgg tactatttca
    38101 tctaagattg ccaagaaagt ctttgtccat ctagctaaaa atggcggtgg cgcgcgtgaa
    38161 tacgtggaaa aagcaggtat ggttcaaatt tcagatccag ctatcttgat cccaatcatc
    38221 caccaagtct ttgccgataa cgaagctgct gttgccgact tcaagtcagg caaacgtaac
    38281 gccgacaagg cctttacagg attccttatg aaggcaacca aaggccaagc caacccacaa
    38341 gttgccctta aactacttgc acaggaattg gcgaagttga aagaaaacta gacagaacaa
    38401 aaccagccct aaggttggtt ttttcttctc taccaactcc caataactat tttggcttta
    38461 tttccagagt attttatggt aaaatgaaga gtaataatat ttattaaaga ggtaaaaaca
    38521 tgattgaagc aagtaaatta aaagctggta tgacctttga aacagctgac ggcaaattga
    38581 ttcgcgtttt ggaagctagt caccacaagc caggtaaagg aaacacgatc atgcgtatga
    38641 aattgcgtga tgtccgtact ggttctacat ttgacacaag ctaccgtcca gaggaaaaat
    38701 ttgaacaagc tattatcgag actgtcccag ctcaatactt gtacaaaatg gatgacacag
    38761 catacttcat gaatacagaa acttacgacc agtacgaaat ccctgtagtc aatgttgaaa
    38821 acgaattgct ttatatcctt gaaaactctg atgtgaaaat ccaattctac ggaactgaag
    38881 tgatcggtgt caccgttcct actactgttg agttgacagt tgctgaaact caaccatcta
    38941 tcaaaggtgc tactgttaca ggttctggca aaccagcaac gatggaaact ggacttgtcg
    39001 taaacgttcc agacttcatc gaagcaggac aaaaactcgt tatcaacact gcagaaggaa
    39061 cttacgtttc tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt gaagaacaac
    39121 ttggcgaaat cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatc gctactgcaa
    39181 aggtagaggg tgttcactct ttttcaaaca gatcagtgtc tgataccctt tcaaaacttt
    39241 cactcggccg tggcgtttat cttaaaaacg tggacgaaga actcacagca gatatctatc
    39301 tctaccttga gtacggagta aaagttccta aggtagcggt tgctatccag aaagctgtca
    39361 aagatgccgt ccgtaatatg gctgatgtag aactcgctgc tatcaatatt cacgttgcag
    39421 gtatcgtccc agataaaaca ccaaaaccag aattgaaaga tctatttgac gaggacttcc
    39481 tcaatgacta gtccactatt agaatctaga cgccaactcc gtaaatgcgc ttttcaagct
    39541 ctcatgagcc ttgagttcgg tacgaatgtc gaaactgctt gtcgtttcgc ctatactcat
    39601 gatcgtgaag atacggatgt acaacttcca gcctttttga tagacctcgt ttctggtgtt
    39661 caagctaaaa aggaagaact agataagcaa atcactcagc atttaaaagt aggttggacc
    39721 attgaacgct taacgctcgt ggagagaaac ctccttcgct tgggagtttt tgaaatcact
    39781 tcatttgaca ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc aaaggacttc
    39841 tccgatcaaa aatctgcccg ttttatcaat ggactgctca gccagtttgt aacagaagaa
    39901 caataaaaag aaaaagtgtt tgatagatat caaacacttt ttctttgcct cccactatct
    39961 aaaaaaatga taatagatat aattgtaaac aaaaatccag ataggttttg catgattgag
    40021 aaagttaaaa aaactatggc agagaatcgt taatctcaga ttgtcggtag aacgataaac
    40081 aagggcaaaa aagaaaccaa tcagactata atataataaa ctaattggat ctctgtgaga
    40141 tagtatcaaa tggctaatcc caaagataag gcctgataag atgacatcta aatagtactt
    40201 tgacttagga aagaaggtat tcatcaaata ccctctatca agagtctcct caaaaacagg
    40261 accgatgatt acaagcagga caaaagataa gatagtcgat aaaaaggttg gttgtccatt
    40321 tgaaagaacc acggtaaaat actcatcatg aatattccta tggttaatca aatgagcata
    40381 gcgtgcctaa aaattaccga gaatctgata aaccacatac gttgcaaata agtagaagac
    40441 aaatgaccag ttccagctct ttttttcaaa gataaagagc atctttttct tttttaacct
    40501 ccaaatcaat agaaggaaac ttcccactaa taccattgtt aaaataagag aatagacatc
    40561 agctcctaac cctaaaatga tcgtcacata caatccaatt gtttgtggta aataggtaga
    40621 tagtaaaata ataagcaaaa atattccaaa ttgtcttagt ttttttgtgt ttctcatcgt
    40681 acttttttga aagattaccc tgctcggaag ccgtacttcc aagcatctat ataagaatta
    40741 agtgcccctt gcctcatata gggagcaaat tctctataat ataaccatct actatatcca
    40801 tcttcccaaa cagcaagacc acctgaagtt tgctccaagt cctcagttga aagaactgta
    40861 aatgtatttg tacctgtcat tgcaagtacc ttcttaaaat agattgttgt aggctcacat
    40921 ttatagtata tttctttttt tgtctatttt atagtctatc tcctcaactg tcaatttttc
    40981 aacctgaatt gcatttttcc ataaaaaatg agacctttct agtctcattt agtcattctt
    41041 agtattttct aaatcgttga tagcgttctt ccagcaactc ttctagcggt ttttgtgaaa
    41101 gtctagccag ctccgtttgg agttcttttt tgacactctt aatcagttct ttactagaaa
    41161 gtcctacttc agaaatcacc ttatccacca cgtccatttc taacagttca tgcgaagtga
    41221 ttttcatcag ttctgctgct tccatggcgc gagtaccgtc cttccataaa atggaagcaa
    41281 agccttctgg actgagaatg gcatagatag aattttccag catccagaca cggtccgcga
    41341 cagctagagc cagagccccg cctgaaccac cttcaccgat aataatggcg ataataggaa
    41401 ctttcaggtc actcatttcc atgagattgc gagcgatagc ttccccttga ccacgttctt
    41461 ctgctccgac accaggataa gcacctgctg tattaataaa ggtcacaact ggacggccaa
    41521 atttctcagc ctgtttcatc aaccgcagtg cctttcggta gccttctgga tgtggttggc
    41581 caaaattccg tttgaggttg tcttgcaaac tcttgccttt ttggatacca acaactgtta
    41641 cagcttggtc tccaagccaa ccaataccac caacaactgc accatcatca cgaaaagaac
    41701 ggtcaccatg taattggata aattcatcaa aaatgcctgt cgcaaagtcc aaggttgtca
    41761 agcgactctg ctcacgcgct tctctgacta tttttgcaat attcatctag gactccctcc
    41821 atgcaatctg actaggctag caatcgtatc tggtaagtct cttcttttga caatagcatc
    41881 cacaaagcca tgttctaata ggaattctgc cttttggaaa tcctcaggca agctttcacg
    41941 aaccgtattt tcaatcacac gacgcccagc aaaaccaacc aagctctgtg gttcagccag
    42001 aatgatatcg ccttccatag cgaaagaagc tgtcacacca ccagtcgttg gatctgtcaa
    42061 aatggtcagg taaaagagac cagcatttga atggcgttta accgccgcag agatcttagc
    42121 catctgcatg agactcatga ttccttcctg catacgggct ccaccagagg ctgtgaatag
    42181 gacaactggc aatttttcga cagtcgcata ctcaaacaaa cgagtgattt tttcacctac
    42241 aaccgtaccc atagaagcca tgataaagtt agaatccata atcccaagag ccacagtctg
    42301 acctttaata agagcagttc ctgtcacaac ggcttcatgc agacctgttt tttcacgcat
    42361 agatgccagt ttcttttggt aaccagggaa atgcaaggga tccttgcttt caatccctgt
    42421 aaacaattct ttgaaggttc ccatatcaat cgtcaaagcc aagcgttctt gggcagaaat
    42481 acgaaaggta tagctacagt gcggacagat acgttcactt cccagatcct tctgatagat
    42541 ggtatgctta cagcctggac actgggaaaa taattcatct ggaacctctg gcttagcttg
    42601 aggtttttcc ctaaccgaac gattgggatt gattcgaata tacttatctt ttttactaaa
    42661 tagagccatt gattcccctt ttcggtttaa actcttaaag tcattttatt ctttttcttg
    42721 atatttaggt aagaaggttt ccatcaagaa ggaagtatca taatccccag caatgacatt
    42781 gcgatctgaa atgaggtcaa gctggaaatc tgcattggtc tgcactcctt caatctctaa
    42841 ttcatagagg gcacgttgca ttttcatcaa ggcgtcaaaa cgattttcgc cgtgtactat
    42901 gattttggca atcatactat cataataagg cggaatggta taacctggat aaactgctga
    42961 atccacgcgc aagccaactc caccacttgg cagatagaga ttagtaatct tacctggact
    43021 tggagcaaag ttaaaggctg ggttttctgc attgatacga cactcgatgg catgaccacg
    43081 taggacaata tcttcttgct taacagacaa aggctgacct gccgcaatgc aaatctgttc
    43141 cttaacgata tcaacacctg aaacaaactc tgttactgga tgttctacct gaacacgagt
    43201 attcatctcc atgaaataga aattgctact tgcttcatca agaagaaatt caatggttcc
    43261 tgcattctca tagccaacaa actctgccgc tcgaacagca gcagcaccta tttcatgacg
    43321 cagcgttttt ccgattgcaa tcgagggact ttcttccaaa accttttggt tattcctttg
    43381 aagagaacaa tcccgttcac ccaagtgaat cacatgtcca tgctcatcac ctaggatttg
    43441 aacctcaatg tgccgagctg gatagataac ccgttctatg tacatggcac cattgccata
    43501 attggccttg gcctcactag aggcagtttc aaaggcagaa acgaggtcat ctggtttttc
    43561 aaccttacga atccctttac cacctccacc tgctgaagcc ttgagcataa caggatagcc
    43621 aattttttca gcaacaatca aagcttcttc agagttatgc acttctccat ctgaacctgg
    43681 tataacaggc acacctgctt taatcatctg agcacgcgca ttgatcttat cccccatcat
    43741 atccataaca tgaccagatg gaccgataaa cttgatacct acttcttcac acatggtcgc
    43801 aaatttggaa ttttcactga gaaatccaaa accagggtga atagcttctg cctcagtcaa
    43861 gactgcagct gatagaactg cattaatatt gagataagac tctgttgcct tgccaggacc
    43921 aatacaaact gcttcatctg ccaaaagcgt atgaagagct tccttatcag cagttgaata
    43981 aaccgctacc gtcgcaatcc ccaattcacg tgccgcacgg ataatacgaa ccgcaatttc
    44041 accacgattg gcaattaaaa tttttcgaaa catggagaac ctccttagtt cccaattgca
    44101 aaagtaagga taccactggc tgcaagcttg ccatccactt cagcctttgc ttcaaccaca
    44161 gctatggtgc cacgacgttt tacaaaagtc gctgtcataa ccaattggtc gcctggtaca
    44221 acttgcttct tgaacttaac cttgtccata ccagcgtaaa agaccagttt tcctttattt
    44281 tcaggttttg ataactccaa cacaccagca gtttgcgcca aggcttccat aatcagaaca
    44341 cctggcataa ctgggtattg aggaaagtgg ccgttaaaga aaggttcgtt aatggtcaca
    44401 tttttgatag caacaatggt atcctcgctc acttccaaga cacggtccac tagaagcata
    44461 ggataacggt ggggaagagc ttctttgatt ccttgaatat cgatcatttg atacgtacca
    44521 atcctttacc aaactcaacc atttcttcgt tagagacgag aatttccgtt accacaccat
    44581 ccttaggagc tgggatttca ttcatgactt tcatggcttc gataattacc aatgtttgac
    44641 cttttttgac actatcacca actgtaacga aggcaggttt atctggtcca gcagccaagt
    44701 aaaccactcc aacaagtgga ctctctacaa gatttccctc actagccaca cttgcttcag
    44761 ctggagctgg aacttcttct gctacagtct ctgctggagc agatgtagga gctactggac
    44821 tcggtgttgc tagaacgggt gctggagcga cttgagttgc aacttcaggc acaggtcttg
    44881 cttcattctt gctaaactgc aactcatccg tcccattttt ataagaaaat tctctcaaac
    44941 ttgactggtc aaattgagtc atcaagtctt taatatcgtt taaattcata cttatctatt
    45001 ctcccaacgt ttgaaagcaa gaactgcatt gtggcctcca aaaccaaaag tatttgaaat
    45061 agcgtatgga atttctttct ccaagccttg tccataaacg acattagctt cgatataatc
    45121 tgatacttca cttgtcccag ctgtcattgg tacaaagtta tgacgcatag cttcgatggt
    45181 gacgatagct tctactgcac ccgcagcccc cagtaaatgt cctgtaaaag acttggttga
    45241 tgatacaggt acttccttac caagaacagc tacgatagct ccactttctc ctttttcatt
    45301 ggcaggagtt gacgttccgt gagcattgac ataggctact tgctctggag aaatctcagc
    45361 ttcttccaag gctagtttga tggccttgat agctccctga ccttctggat gtggagaagt
    45421 catgtggtag gcatcacaag tatttccgta accaaccact tcagccagga tagtagctcc
    45481 acgtttttca gcgtgttcaa ggctttctag aaccaacatc cctgaacctt cacccataac
    45541 aaacccattg cgatccttat caaatgggat cgaagcacga gttggatcct ctgtagtaga
    45601 gagagctgtt aaggcttgga aaccagcgat ggcaaaaggt gtgatagaag cttctgttcc
    45661 tcccaccaac atcacatctt ggaaaccaaa cttaatggag cggaaggcat ccccaatcgc
    45721 atcatttgat gaagagcagg cagtattgat agatttacaa acaccgtttg caccaaaacg
    45781 catggctaca ttcccagaag ccatatttgg taaagctttt ggaagagtca ttggtttgac
    45841 acgtttgggt cctttttcat gaaggcgaag tacctgatct tcaatttcct tgattccacc
    45901 aataccagat gcaacgataa caccaaaacg atccctatta agagcctcta catcaagatt
    45961 ggcatgattt acagcctctt gggctgcata caaggcatat aaagaatagt tatcaaaacg
    46021 gttggtatct ttttttacaa agtatttatc gaacggaaaa tcttggattt ctgccgcatt
    46081 atgcacatca aagtcactat gatcaaattt tgtaatgcca ccaatgccga ttttcccagt
    46141 tgctaaacta ttccaaaatt cttctggtgt atttccgatt ggagatgtta ctccataacc
    46201 tgttaccact actcgattta gtttcattct tttcacctct agctttcgct acatacttaa
    46261 gccaccatca atggcaatca cttgaccagt tagataatct tggcctgcta aaaatactgt
    46321 caaatctgca acctgctctg cctgcccaaa ttctttcatc ggaatctgag ctagtgtagc
    46381 ttccttaatc ttatctgata agatagctgt catatcagac tcaatcattc ctggagcaat
    46441 cacattgact cgtatattcc gactagcgac ctcgcgtgcc acagacttgg taaagccaat
    46501 caagccagcc ttagaagcag catagttagc ttgaccaata ttccccatca aaccaacaac
    46561 actagacata ttaatgatag caccttctct ggctttcatc atcggtttca agactgattg
    46621 tgtcatatta aaggcaccag tcagattgac cttgagcact ttttcaaaat ctgcttctgt
    46681 catcttgagc ataagagtat cttgggtaat ccctgcattg ttgaccaaaa catctactga
    46741 acccagttct gcaatagctt gatcaatcat acgcttagcg tctgcaaaat ctgatacatc
    46801 tcctgaaatg ggaaccacct tgataccata gtttgaaaac tcagcgagca attcttctga
    46861 gattgcccca cgactgttta agacaatgtt ggctcctgct tgagcaaact tgtgggcgat
    46921 ggcaagacca attccacgac tcgaacctgt aataaagata tttttatgtt ctagtttcat
    46981 ttttttcctt tcaaaacttc tacttatttt agtctatttt tctaaaagtg ctactaaact
    47041 cgcttgatct tccacatgag ctaagtgagc agtttgatca atttttttaa caaaacctga
    47101 caagactttc cccggtccaa tctcgataaa gttgcttatg cctgcttctt gcatgacccc
    47161 aatactttca tagaaacgaa cgggttcctt gacctgacgc gtcaagagct gagcaatgtc
    47221 ctctttttgc atcacagcag cttctgtatt gccgactagg ggacaagtaa aatctgaaaa
    47281 acttacctga gctagagttt cagctagttt ctggctagct ggctcaagga gagcggtgtg
    47341 aaagggacct gacaccttaa gaggaatcaa gcgtttggca cctgcttctt gcaaaagttc
    47401 aaccgctcga tcaactgcaa ccacttctcc agcaatgacg atttgtgcag gtgtgttata
    47461 gttggctgga gtaaccactc caagttcaga agctttttga caggcttctt caatgacctc
    47521 tactggcgta ttgagaactg ctaccatctt gccagagtca gcaggagccg cttcttccat
    47581 ataggctcca cgcttagcta ccaaggcaac cgcatcttca aaatccaagg cgccgcttgc
    47641 caccaaggca gagtattctc caagagacaa accagcaacc atatcaggct gatagccctt
    47701 ttcttgcaat aaacggtaga tagcaaccga agtcgctaga atggctggtt gcgtatagcg
    47761 ggtctgattg agtttgtctt cttccgtatc gatgagataa cgcaaatcat aacctagcac
    47821 ctgactcgct cgatcaatcg tttctttaac aatcggatac tgatcataga aatcccgtcc
    47881 catccctaga tactgggcac cttgaccagc aaataaaaag gctgttttag tcatttctta
    47941 caactcctgc ccagcgagag gcttcttctt gaattttctt agcggctccg taatacaaat
    48001 cttttaggat ttcttcagct gtttcttctt tagaaacaag ccctgcgatt tgacctgcca
    48061 tgacagagcc accatccaca tcaccgtgaa caactgcttt ggctagggca cctgctccca
    48121 tttgttcaaa gatttctaaa tcaggatctt cctgcttaaa ggcatctttt tcagccagtt
    48181 caaaatctct agtcaactga tttttaatag cacgaacagc atgaccaaag tgctgagctg
    48241 aaatcgtagt atcaatatcc cttgctttta aaattttctc cttgtagttt ggatgggcat
    48301 tcgactcttt tgcaactaca aaccgtgtcc ccacctgtac agcctctgca cctagcataa
    48361 agccagccgc agcaccttca ccatccgcaa ttcctcctgc agcaataaca ggaatagata
    48421 tagctgtggc tacctgtcgc accaaggtca tggttgttaa tttaccgata tgccccccag
    48481 cttccattcc ttctgcaata acagcgtctg caccgatttt ttccatgcgt ttagctaaag
    48541 cgacactagg aacaacagga ataacgatta tcccagcttc atggaaacgt tccatatact
    48601 tgcttggatt tcctgctcct gttgtgacaa ctttaacacc ttcttcaata acgagatcca
    48661 cgatatcttc cacaaaggga gataagagca tgatgttgac cccaaagggt ttatcagtca
    48721 atgatttgat tttatcaata ttggccttga caacttcttt cggggcattt cccccaccga
    48781 taattcctaa tcctccagcc ttggaaacag cccctgccaa atcaccatca gcaacccagg
    48841 ccatccctcc ttggaaaata ggatagtcaa tcttcaataa ttctgtaata cgcgttttca
    48901 tagtgcctcc aaccttcctt gcttacgtaa tagttcgatt tcaccataat ttgacagtca
    48961 aactattacc taaacaagag ggagtgggtt tctccctact ccttctacta atattctgct
    49021 tattttgctt gctcttcaac gtaagcaacc aagtcaccaa ctgttttcaa gtcattttct
    49081 gcttcgattt ggatatcaaa agcatcttcg atttctgaga ttacttggaa caagtccaat
    49141 gaatctgcgt ccaaatcatc aaaagttgat tcaagtgtta cttctgatgc gtcttttcca
    49201 agttcttcaa cgataatttc ttgtactttt tcaaatactg ccatgatagg actcctttaa
    49261 aataaatagt ttttttataa caatgtgttc accacatgat tacctaaatt gtaagaatga
    49321 gcgtgcccca ggtcaagcct ccaccgaagc ctgatagaag aacagtctgg ctaccatcta
    49381 aagggatgag accttgttct acacactctg aaagtaaaat cgggatactg gctgcactgg
    49441 tattgccata ttccatcata ttggctggaa gtttggctcg gtcaacacca atttttctag
    49501 ccatcttatc caaaatacgg tcattggctt gatgaagtag cagataatcc aagtctgtca
    49561 cctctatagg agattcatca atagtctgct tgatagactt ggctacatct cgaatggcaa
    49621 aatcaaagac tgtgcgtcca tccatcttca aaaacgaatc tgcactttct tgatctgaaa
    49681 atggagaatg caaacctgaa tgcccataag ttaaacactc gctgcgactt ccatcgctat
    49741 tgagactctc agctaagaaa tgctcttgct cgctagcttc taacaagaca ccaccagcac
    49801 catctccaaa caacacagct gttgatcgat ccgaccaatc gactgcctta gagagggttt
    49861 cactaccaat caccaagcct ttttgaaagc gaccagaagc gataaacttt tcagcagttg
    49921 aaagagcaaa tacaaatcca ctgcaagccg cggttaagtc aaaagcaaag gctttattag
    49981 cgccaatatt agcttgaaca cgagcagctg tagagggcat catcgaatct ggagtaatgg
    50041 tagctaggat gataaaatcc agttcttttc ctgttattcc agcttttgcc atcagtttct
    50101 tagcaacctc tgtagccaaa tcactggtag attctgttct tgaaatatgc ctttgtcgta
    50161 ttcccgttcg acttgaaatc cactcatcat tggtatccat aatctgagcc aagtcgtgat
    50221 ttgtaaccac ttgctctggc acataatgag caacctgact tatttttgca aaagccatta
    50281 tttcaaatcc tccaaaaatt ggtaaagatt agtcaaacct ttacccatga cagcaatttc
    50341 ttcctcgctc atgccatcaa taattttttc taccatggcc ttgtggaagc gtttatgcag
    50401 cctatgaatc aagcgaccct tctttgtcaa atgcagatgc accacacgac gatcctgttc
    50461 tgaccgaact cgctcaatgt agcccttacg ctctaaattg ttcaaacttg tcgtaacagt
    50521 tccaagagtt accatcaact cttttgacac ttgacttgga gtcacgtctg gagccttacc
    50581 gatgacatca atcgtatgca tttctttgat ggagatatcc ttaaaacgac tacctctcaa
    50641 gttcacttcc tcaattacaa ggacattgtt aaatatagat gttaaatatt cattgattcg
    50701 ttggtagtcc atttttcata tccctccttc ttcaaaaaac ttttacaatc aaaacatttg
    50761 acagaaagaa ttatatcaaa attcaaagaa tgatgcaagt attttttatt ttcctgtaaa
    50821 tttaggtctt cttctctccg aatgagctcg cactccttct ttgaaatcct ctgtttgagc
    50881 taaggatttc tgtaggttca gttctaaagt agcgtaaccc tgccagtctt taaattggct
    50941 ctcccaaacc aacttcttaa tggcagcata ggaattactt gaagcacgtc ttaatttttt
    51001 aagaagctgt tctctcgtct tttcaagttt ttcagcttca gaaacgcgat aaaccaaccc
    51061 ccattctagg gctttttctg ccgttaaagc ctctcctgtc atagctaatt gagcagcacg
    51121 cgtcacaccg atactgcggc tcaagagatg aattccccct gcatctggag ccaaaccaac
    51181 accaacaaag gcttggataa acttagcctt atccgtcgcc aaacagaaat ctgccgcaac
    51241 agccatattc gctgcggcac ctgcaacagc accgtcaact tccattaaaa caggtttggc
    51301 tatttgcttg attttataag aaatcgtatt gaccaactct gcgatttttg tcaatgatgg
    51361 aatatcatcc tcatccactg cccgcttcat ctctaccaaa tctcccccaa ctgagaagac
    51421 ctttccattg gcattgatta agataaaatg cacagctgga ttttcttctg ccaaagtcag
    51481 agcttctaaa atctcctcac acatgggaat atgaaaacca tttgcgacct caggacggtt
    51541 caaggtaagg attgccaagt cctcttcaag ctgataaata atgtgttcca tcagggctcc
    51601 tttttatttt ataagcagtt tatactcttc gaaaatctct tcaaaccgcg tcagcttcca
    51661 tctgcaacct caaagcagtg ctttgagctg acttcggcta gcttcctagt ttgctctttg
    51721 attttcattg agtgttaaat tatttcactg tcaaagtata tcttttttag gagcagaaag
    51781 caagaaaaaa tcgactgaaa gtgtctcagc cgataagaaa ggctcgcttt aggctagaaa
    51841 gcatcttatt ttcttcattg aaaaaagcct ttctttctgc tataatcgta taaaatactt
    51901 actttaggag ttcttatgaa agttgttaaa tttggaggta gttctcttgc ctctgctagt
    51961 caattagaaa aagttttaaa catcgtcaaa agcgattcag agcgtcgttt tgtagtcgtt
    52021 tctgcgcctg gtaaacgcaa tgctgaagat actaaggtta cggatgccct gattaaatac
    52081 taccgcgact atgttgcggg taacgatatt agcaagagcc aaagctggat tatcgaccgc
    52141 tatgctgcta tggttagtga attgggacta aaaccagctg tgctagaaaa aatttctaaa
    52201 agtattcacg ccttggccac tcttcctatt gaagaaaatg aatttctcta cgatactttc
    52261 ctagcagccg gtgaaaataa caatgccaaa ttgattgctg cctactttaa ccaaaatggt
    52321 atcgatgcac gctatatgca ccctagagaa gctgggattg tggtcacaag tgaacctggt
    52381 cacgctcgca tcattccatc aagttatgac aagattgaag aattgacaaa caccaatgaa
    52441 gtccttgtca ttcctggttt ctttggtgtc actaaggaaa atcaaatctg tactttctca
    52501 cgtggaggtt ctgatattac aggttctatc attgctgctg gtgtcaaagc tgacctctat
    52561 gaaaacttta cggacgttga tggtatcttt gcagcccacc ctggtattat ccaccaacca
    52621 cactcgattc ctgagttgac ctaccgtgaa atgcgcgagt tggcctatgc aggcttctca
    52681 gtccttcatg acgaggctct tcttcctgcc taccgtggaa aaattcctct ggttatcaag
    52741 aataccaaca accctgacca tccaggtact cgtatcgttc taaaacacag taatgatgaa
    52801 tttccagttg tgggaattgc tggtgactca ggctttgtca gcattaacat gtcgaaatac
    52861 ctcatgaacc gtgaggttgg atttggccgc aaggttctgc aaatcctgga agaacttaac
    52921 atcggttggg aacatatgcc aacaggtatc gacgatcttt ctatcattct ccgttctcgc
    52981 caactaactc ccatcaagga agaagaaatc ctgcgtcagt tggttcaaaa ggctaaagta
    53041 gatcatgcag aaatcgaaca cgacctttct atcattatga ttgttggtga aaaaatgaag
    53101 agccacatcg gagtgactgc tactgcgaca cgcgctctat ctgaaaacaa aatcaacatc
    53161 cagatgatgt ctcaaggttc tagtgaagtt tctattatgt ttgttgtcaa taaagaccaa
    53221 gagaaagcag caattaaagc cctctacaat gccttttttg gagaaagtaa ggaagactaa
    53281 gcatggccca atcacttaac aaaacagtac tcctcagtac gacaggcact tcctacctct
    53341 ctatcgctgg gaaagttggg aaattccttg tcggagatca ggctttggaa ttttacccag
    53401 atgtcaatgt cgaacaattt atccagattc cttggagcca tatcaatcag attggagcca
    53461 atgtcactgg acgcaaaatc agccgccact tcgaagtctt tacagacaaa ggaaaattcc
    53521 tctttgcttc aaaagactca ggtgccattc tcaaaattgc acgcaaaaaa ctaggcaatg
    53581 acaaggtcgt caaacttccg accctgattc agacaattag ccaaaaattt aaaaatctat
    53641 ttgcaaaaaa gtagaaactt tagtataatc atagcaacgg ataagtaggt tatcttcttc
    53701 tttcagaaag tctgcgggta ctgcgagcag ataggaggga taggtgaaat tctaccgtta
    53761 ataacaatta catacacaat caagtgcaca cctgtgaagt tggatggaac cgtggccctg
    53821 ccactccaac gttttgtcag gcgtgctttt ttcataaagg agttcttatg ttagatatca
    53881 aacgtattcg tacagatttt gaagctgtcg cagaaaaatt agctacacgt ggtgtagatg
    53941 ctgctgtctt gaatgaaatg aaagaaatcg atgctaaacg tcgtaacatc ttggtcaagg
    54001 ttgaaactct caaagcagaa cgtaacacag tttctgctga gattgcccaa gctaagcgca
    54061 acaaggaaaa tacagatgac aagattgctg ccatgcaaaa tctatctgct gaggttaaag
    54121 ccttggatgc tgaattggca gaaatcgatg ctaaattgac agaatttaca acgactcttc
    54181 caaatatccc agctgacagc gttcctgttg ggactgacga agacgacaat gtggaagttc
    54241 gccgttgggg tactccacgc gagtttgact tcgaacctaa agctcactgg gatctcggtg
    54301 aagaccttgg tatccttgac tgggaacgcg gtggtaaggt aacaggcgct cgcttcctct
    54361 tctataaagg cctcggtgct cgtttggaac gtgctatcta caactttatg ttggatgaac
    54421 atggaaaaga aggctatact gaagtcatca caccttacat agtcaaccat gattctatgt
    54481 ttggtactgg tcagtatcca aaatttaagg aagatacttt tgaactcagc gataccaact
    54541 ttgtcttgat tccaactgct gaagttcctc tgacaaacta ctaccgtgat gaaatcttag
    54601 acggcaaaga tcttccaatc tacttcactg ctatgagtcc gtcattccgt tctgaggctg
    54661 gttctgccgg tcgtgatacg cgtggcttga tccgtttgca ccaattccac aaggttgaaa
    54721 tggtcaaatt tgccaaacca gaagaatctt acgaagaatt ggaaaaaatg acagccaacg
    54781 ctgaaaacat tcttcaaaaa ctcaaccttc cataccgtgt cgttgctctc tctactggag
    54841 atatgggctt ctcagctacg aagacttacg acttggaagt gtggattcca gcacaaaaca
    54901 attaccgtga aatctcaagc tgttcaaaca cagaagattt ccaagcccgt cgtgcccaaa
    54961 tccgttaccg tgatgaagca gatggcaagg tgaaactcct tcataccttg aacggttctg
    55021 gacttgcagt tggacgtaca gtggctgcaa ttcttgaaaa ttaccaaaat gaagatggtt
    55081 ctgtgaccat cccagaagca cttcgtccat acatgggtgg agctgaagtc atcaaaccat
    55141 aaaaaataag gtttagctat ttctagctag acctttttcg taaccaaatc agataagcac
    55201 ctagtacaaa gaataaaata gttaggcata taatggtttc agccaatacc aggtaatcca
    55261 gaaatggaag tttcaaaatt ccctgagcca tcttgagcga ggtcgctgtg ataatggttg
    55321 ggaaggtgag ggctgagaag gctggttgaa aaccttgttt taaaatgttg ggcagacgag
    55381 ttaaaacaaa gaaaaagaag gattgagaag ccaaaatcat gacaatcaag acccaagtcg
    55441 gcaggctggt tcctcctact cgaactagag aagccaagag tagagagaaa ggagcacagt
    55501 agattccttc ttgtccaagc aaggctagtg ggagtggatg tttctttaaa tcgctataaa
    55561 taaggggata gagatagaag gtcaagagaa aaccaaaact caaggtcgca taggcaattt
    55621 cgataatacc taccagagga taggtcaagg cagccactgc tatccccaca tagagaaccg
    55681 tccaacttgg agtggcatga accctccgcc ctggacaagc aaacttgatg gtaaaaccag
    55741 caatcaaggt caaatccaag agaaatgaaa accaccaaat cccttgtgct accaaaggaa
    55801 gataagagaa tacgcgaaag acataggtcg ataaaatcat cccagccata ggaaaggttg
    55861 ccattcctga caaaagaggg ggcttggtca attcttgctt ggtttctttc caattaaaga
    55921 gatgcagaat tagaaagtaa atccataaaa ccaaaccagt cagactaaaa agatgggata
    55981 gaaccggcaa cgtatctaaa ataagatttc cagctcctgc caaacctagc aaacaacctg
    56041 aaaatactaa ggggagtttt ttcatcctaa cctccaataa tcatgttagt ttcagtataa
    56101 cataaaagcg cttaaatgag gatttaaaaa aacgaagtcc gcttatttca gacttcattt
    56161 tactcagata tgaattaggc ataaggttgc aattctggat taattggtgt attagctaag
    56221 ttgttggcat agttacagag gattgctagg ctgacaccaa aaaccacatc caaggcattt
    56281 tgttgagtgt agccagcttc taaaaactca gacaaggctt catctcctac acgacccttg
    56341 gtattgataa ctgccaaggt aaacttagct agggtatcca atttaggatc tgtttcaatt
    56401 ggagtacgat tgcgaagagc ttgaatcaag tcatcattca tctggatttg ttttatggaa
    56461 aaggctgtgt gacctgcgac acagaaggca caaccattgg tcacggctgc cgtgatttgc
    56521 accacttcac gctcaacggg tgtcaggctg ttgcgacggt ggatagatga gacaatttgg
    56581 taggcttcta aaacagtcgg ggcattggcc aagagaccga ttaggttggg aatatagcca
    56641 ttgttgtctt tttctactgt ttcaagaatt tctttcactt ctgctggtgc tgactctact
    56701 gtatggatag taaatgttgt cataagatac ctcttttctt attattgaca ctaatattat
    56761 tggaaaatct tataaaatcc tgattcctaa gtttatctaa gataaagctt tattctctca
    56821 taagattttc gttgttatat tagtttatca cacttccaat cacttgcata atatatatta
    56881 tatatcaggc tgataaaaat tatttatagg caaaaaaatc acacgagctg tgtgattcca
    56941 ttatttgtca aaatactttt tagtttcagc aataacgact ggcgacaaga ccaagagggc
    57001 aatcaagttt ggcagagcca tcaaggcgtt aacgatatct gcgataatcc agaccatatc
    57061 caactcgata aatcctccta acaagaccat gagcacaaaa accacacggt agagccagat
    57121 aaagcgagcc ccaaagagga actcaaaaca gcgttctccg taatagttcc aacctagaat
    57181 cgttgtaaag gcaaaaagta caaggaagat ggtcaagagg gcaggcccaa agtgtgaaaa
    57241 gactgttgag aaagctgact gagtcaaggc aaccccattc aagtcaccac tccaaactcc
    57301 agttaccaag atggtcaaac cagttagagt acaaatgatg agggtatcaa taaaggttcc
    57361 tgtcatggaa atcaaacctt gctctactgg ttcatttgtc ttggcagctg cagctgcaat
    57421 aggagcagaa cccagaccag attcgtttga gaacacacca cgcgccacac cattttgaat
    57481 agccatccga acgctagcac cagcaaatcc acctaccgca gcaaggggac taaaagctga
    57541 ggtaaagact aaagcgattg tgccagggat ttttccgata ttaaagaaaa taactgtaag
    57601 agttcctaag atataaatga gggccataaa aggaacaaca gtagttgaaa ccttagaaat
    57661 agacttgagt ccaccaaaga ctgcaatcgc tacaaagaca gacaagacga gagctgtgat
    57721 ggctggcgaa atcgtcgttg tattttggat agattctgta atcgagttga cttgggtgaa
    57781 ggttccgatt cccaagagag caaccaatac tcctgctact gcaaacaaaa cagcaagtgg
    57841 tcgccacttt tctcccatcc ctagaaggat atagtgcatg ggacctcccg ctactgcacc
    57901 atggtcgtcc ttggtgcggt atttgatggc caagagtcct tccgcatact tggtagccat
    57961 tccaaagaaa gccgccatcc acatccaaaa tagagctcct ggtccaccaa ccttgatagc
    58021 cgtcgcaact cctatgatat ttcctgttcc aacagttgat gccaaggctg tacacagagc
    58081 tgcaaaactg gatacatcac catgtccctt atcctggata aaaataagct gaaaggcctt
    58141 gggcagacgc aaaacctgca agagtcctag ccgcatggtt aggtaaatcc ctgttccgac
    58201 caataaaatc aagaggggcg gtccccaagc aaaagcatcg attgatttaa gcaattctaa
    58261 catttccttc tcctatcgtt tcaaccccaa aagaaagagc acatgcaaga tacatgtact
    58321 ctggaatgct tagataaatg ctaaaaagcg gtctatccta gctctgtcct tttacctgag
    58381 agtttgagca gttgcctgcc ttgccccttc ggtgccttta cggtctctcc agagttccgt
    58441 ccatttacag tcatggaaaa tcaaacgatt ccccacttct attaaacttc attcggtgtt
    58501 ggtatttaat tgattctaat tttacaaaaa atgttggctt ttgtcaatgt gtttattagt
    58561 aaaaattagt tcaacagttt ttactttata aagtccagaa tactgctatc ctttaaaagt
    58621 gacaatagtc gcaccactgc ctccagcatt ttgtggggca tagccgaaac tcttgacatg
    58681 tttgtttctt tgcaagtatt tggtaactcc ttcacggatg actcctgttc cgataccatg
    58741 gatgatatca acttgagcca tattgttaag caaggcttgg tcgatgaagg tatctagctc
    58801 attcatggct tcttcatagc gcttgcctcg aagatccagt ctagcttgag gtcctcgccc
    58861 agaagttcgt ttcacaacat tgacctgttt cttcttgact ggtttttctt gctgggcttg
    58921 aacaagatca aactctttct cttccaaggt catcttaatc aagccaactt gggcttccca
    58981 gcgaccgtcc ttgagttgac tggtcaaggt accacgctga ccataactga gaaccacgat
    59041 atcatctccc acctttggag ctcgtttttt cttggccttt tgaaggacct tatttttaga
    59101 caagtccact ttttcaggag ccaatttttt caacttggcc ttggcttcaa tgatttcgtg
    59161 gggcttgagt tgggatttac tgtggagatt tttgagaatc tggtcacttt cacttagggc
    59221 catatccaca atctcagcag cctgttcacg cgccttgtta agctcggttt ccttttcacg
    59281 attaagctcg ttgtagagtt tttttagcgc acggttcatc ttgagatttt cttgctccac
    59341 ctcacggata ttgtccaaac gtttgcggct ttccagcgtc tgctcttcta attgctcaat
    59401 gatacgattg acgtcattgt cctgatcgat ctgctgactg gcatctccta cgataacttc
    59461 agataggcct agacgtttgg caatttcaaa ggcattactt cggccaggaa caccctgcat
    59521 aaagcgatag gtcgggcgaa gagttgcagt atcaaactcc atactggcat tttgcacaaa
    59581 ggctgtctca ataccgtagg ccttgagttc tggatagtgg gtcgtcgcca tggtcttgat
    59641 ttgacgcagg cgaaggtcct ccagaatagc catggcaagg gctgctccct cttggggatc
    59701 agtaccagcc cccaactcat ccaaaagtaa gagtgaatgt tggttgacct tgccaagaat
    59761 atccacgata ttggtcatat ggctagagaa ggtagacaag ctctgctcaa tagactgctc
    59821 atctccaata tcagcaaaga tttcttcaaa aataccaaca cgacttccct tgtctgctaa
    59881 aatcggcaat cctgactggg ccatgacctg tgtcaagccc agagttttga gcatgatggt
    59941 cttcccacct gtattgggac ctgtaatgac aatagctgtt aaatcttgac caaaatggac
    60001 atcatttgcg acggcatttt tgaccaaagg atggcagaca tggagcagtt gaatctcttg
    60061 attttctgac agctgaggca cgactgcttg tctttcttgg ataaatcgaa ccttggcacg
    60121 aatcaagtcc agatgaccga taatccaagc gtcattagca atctcagccg catgagggcg
    60181 gacacgctca gaaatttctt ggagaatgcg aagcatttca tagcgctcat ctgctcgcag
    60241 actagcaatt tcttcgctca gtttgactac ctcacgtggt tcgatataga cggtgtttcc
    60301 actagcagaa atatcatgaa cgacacctgc aatcttattg cggtaggtgt ttttgactgg
    60361 taaaacctga cggccatttc tgctagcaac aattccttcc gtcaacatct gcgctttttg
    60421 cttgagcaag tcttgtaaaa catcgcgtac ctgactctcg ctatcatgta tttttcgacg
    60481 gattcgcgcc aattcttcac tggcaaaatt ttcaatgaaa cccgcatcat taaaggcctg
    60541 aagatttcct tgtaattgcg gaaaatcatg taatttctca aaccaaaggg ctaattcttc
    60601 caagctgaca ttttccagat tggtgtaaaa attttgaagt tctcggctgg caagaagcac
    60661 gcgtttcaag agtaggaact cctcgatatt gagatccgct cccatctcca acctcttgca
    60721 gactcctgca atttccttag ttgagagaat agtaaaatgc ggttgctcga cgaaaagagc
    60781 ctgcatttcc ttcatctcag caaaagcctg tttgatttta tctgctttgg cagtcggagc
    60841 cagttgtctc aattgctcca agccctgctc ggtcaacaaa tgaggctcaa acaaggcctt
    60901 gaccttatcg aactctaatg tttctaatat tttcttattc atctttattt ccttgtcttt
    60961 gaatgtctag gtgtggtagc tttttacatt ctgatagatt cgagtcaaat ctgtaaacaa
    61021 agggctagga aaactcctgc cctttttatc cgattaaatt tgtcacccag atttgtttga
    61081 gccaactggt tgttatcggt atgctctgga tgatgtgttt tgcgacgata ctcttttcaa
    61141 gaggattttg tataactgcc atggggatgg tcgccaagat tgtcaaggcc atttgcaaga
    61201 caaataaggt caccaacatg gacaagatac ctgctgaaac ttggaacaac ttaccaccca
    61261 gttttttgct aggaatcaag tgtaagagaa gaccaagcaa acgaccaatg ctatagacaa
    61321 tcccaaatac aagcaagtag ccgatacctg cataaaagac cttatccagc tgaaagagtt
    61381 gatccgatgg gaaaaagaaa gtcccctgac cttcctgcga atttgcataa gggagcaata
    61441 aatggaattg ctctccaagc cccttataaa actggccagc cataaaagcc gatgccatgg
    61501 ctgaaatcag gtaataaacc tgtaagagca ggcctctccg atagccgata taaaatcccc
    61561 aaaccaagac caatagaaga aggaatgaaa tcataaggaa tcctcaatct tgctctgttc
    61621 ttgcttacaa gtcacaagct tgtgacggag ttcttctagc tcttgctcct tatcgtcaaa
    61681 ttcaatctca cggctgagct gagttgataa acagttgact gccaacaaaa gagcgattgt
    61741 ttcatcatct gcgctaggca tttgttcttt aattgcttgg tatttttctg tcgcaacctt
    61801 agcgatttcc tccataaaaa ggttatcatg ttcgcttgtc aaggttaacg attttttccc
    61861 gaatgtaaat ttgaatcgat ttagatttgc cataaaattc acctcacgat attataccaa
    61921 aattcgctaa ttttgtcagt ttttacaaat tttactgctt ttgtggtaca atagaaacta
    61981 tggcaagtat cacactcaca ccaagcgaaa aggatattca ggcttttctt gaacactatc
    62041 aaaccagtct ggctcccagt aagaatccct atatccgcta ctttttgaaa ctacctcaag
    62101 caacggtttc tatctatact tctggaaaaa tcttgcttca gggtgaaggg gctgagaaat
    62161 acgctagttt ctttggctat caagctgtag agcaaaccag cggacaaaat cttcctttaa
    62221 ttgggacaga tgaggtggga aatggttcct actttggtgg gcttgcagtt gtggctgcct
    62281 ttgtcacatc tgaccagcac gactttttac gaaaactcgg tgtgggggat tctaagactc
    62341 tgaccgacca aaagatccgt cagattgctc ctattctcaa ggaaaaaatc cagcaccagg
    62401 cactccttct ctcacccagc aagtacaacg aggtcatcgg agaccgctac aatgctgttt
    62461 cggttaaggt tgccctccat aatcaggcta tctatctcct ccttcaaaaa ggtgttcagc
    62521 ctgagaaaat tgtgattgat gcctttacca gtgctaaaaa ttatgacaag tacttggcac
    62581 aagaggccaa tcgtttcagc aatcctatca gcttagaaga aaaggctgag ggcaaatact
    62641 tgtctgtcgc agtttcttct gtcattgcgc gtgatctctt tctggaaaat cttgaaaatt
    62701 tgggacgaga actgggttat cagctcccaa gtggagctgg aacggcttct gacaaggtgg
    62761 ctagccagat tttgcaagcc tatggtatgc agggactcag cttctgcgcc aaattgcact
    62821 ttaaaaacac tgaaaaagcg aaaaaacgct tagaaaggta agttatgaat tcatttaaaa
    62881 atttcttaaa agagtgggga ttgttcctcc taattctgtc attactagct ttaagtcgta
    62941 tctttttttg gagcaatgtt cgcgtagaag gacattccat ggatccgacc ctagcggatg
    63001 gcgaaattct cttcgttgta aaacaccttc ctattgaccg ttttgatatc gtggtggccc
    63061 atgaggaaga tggcaataag gacatcgtca agcgcgtgat tggaatgcct ggcgacacca
    63121 ttcgttacga aaatgataaa ctctacatca atgacaaaga aacggacgag ccttatctag
    63181 cagactatat caaacgcttc aaggatgaca aactccaaag cacttactca ggcaagggct
    63241 ttgaaggaaa taaaggaact ttctttagaa gtatcgctca aaaagcccaa gccttcacag
    63301 ttgatgtcaa ctacaacacc aactttagct ttactgttcc agaaggagaa taccttctcc
    63361 tcggagatga ccgcttggtt tcgagcgaca gccgccacgt aggtaccttc aaagcaaaag
    63421 atatcacagg ggaagctaaa ttccgcttct ggccaatcac ccgtatcgga acattttaag
    63481 aaacctaaga ggccgagaat caccaatctc agcctcttct tctatcgtga gaaaatgatt
    63541 ggtaactatc taaacttacc agaacagaaa cacctcaact ctcacctatt catgcaaagg
    63601 aattttatgg aagtttattt ttcaggaacc attgaacgga ttatttttga aaatcccagc
    63661 aatttttatc gcatcctcct cctagaaatc gacgatacgg acgcagagga ttttgatgat
    63721 tttgaaatca ttgtcacagg aaccatggct gatgtaattg agggcgaaga ctatactttt
    63781 tgggggcaaa ttgtccagca ctccaagtat ggagaacaac tgcaaatcag tcgttatgat
    63841 cgcgcaaaac caactagtaa gggcttggtc aagtactttt caagtagcca tttcaagggg
    63901 attggtctca agacagctca gaaaatcgtg gatacctatg gcgaaaatac cattgacgaa
    63961 attttgcaac acccagaaaa gttagaaggc atcgcaggac tctctgccaa aaatcgcgag
    64021 gctttcgtct ccactctccg tctcaactac ggaacggaga tggttttgtc caaactagcc
    64081 aactacggca ttcccaacaa actagccttt cagattcaag acttttacaa ggaagaaacc
    64141 cttgatgtgg ttgaaaatta tccctaccag ctggttgagg atatcaaggg tttgggcttt
    64201 accattgctg accaactagc tgaggaacta ggcatcgaaa gtcaggctcc tgaacgcttc
    64261 cgcgccggtc tagttcacag tctttttcag gcctgtatgg aaacagggga cacctatgtt
    64321 gaagcacggg atttgctgga acaaaccctt actctccttg agtcttcccg tcccgtggaa
    64381 ctagaccccg gccaagttgc ccaagagctc tcctacctga tcgaagaaga caaggttcag
    64441 cagattgata ccaagatctt tgacaacagc ctctttttcg ctgaggaagg tatccgcagt
    64501 cacttgattc gtatccttga aaaaggaaaa cagaagagcc aagatttaga aactattcaa
    64561 aagcatatca ctactgtcga gcaagaactg gggattgagt atgataacat tcaaaaacag
    64621 gctatctgtg atgctatcca gaataaggtc tttatcctga caggtggacc tggtactggt
    64681 aagacaactg ttatcaatgg gatcatcgct gtttacgccc tgttagaggg acttgacctc
    64741 aggaagaaaa gcaacctgcc cattcttctt gctgctccaa ctggtcgagc tgctcgtcgc
    64801 atgaatgaat tgacaggttt gcctagcgcg accatacacc gccacttggg aatgacaggt
    64861 gacgatgata ccagtcatct ggaagattac ctagatgctg actttatcat cgtggatgaa
    64921 ttctctatgg tggatacttg gctggccaat caactcttct ccaatatctc ttctaacagt
    64981 aagatcctca tcgtaggtga cagtgatcag ctaccttctg tcagtcctgg acaggttcta
    65041 gcggatctgc ttcatattcc tttgattcct cagactcgct tggaaaaaat ttatcgacaa
    65101 agcgaagaat caaccatcgt caccctagct agtcagattc gacagggcat cttgccagct
    65161 gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa ttgctagtgg ccatattcct
    65221 gccactattg aaaaaatctt aggtgccgcc ctcagaaata gtattcctgc ccatgatatc
    65281 caagttctgg ctcctatgta ccgagggacg gcagggattg atgctatcaa tcagctcatg
    65341 caagacctgc tcaatccccc acaaaaagat caactcagtt ttgaagctcc tcagtgccac
    65401 tatcgtaagg gagacaaggt cattcatttg gttaacgatg ctgaaatcaa tgtctttaat
    65461 ggggatttag gagctatcac agacctgatt cctggtaaat acaccgaatc gaaacaagac
    65521 gagattgtca ttgattttga tggtaatgaa gtctcttacc cccgtaacga atggtacaag
    65581 attcgcttgg cctatgccat gagtattcat aagtctcagg gaagtgagtt cccagttgtc
    65641 atcctaccga ttactagtgc tagccgacgt atgctggagc gaaatctcat ctacacagcc
    65701 attacacgtg ccaaaagcaa actcatctta ctaggcgaat tacaagcctt cgactatgct
    65761 acccaacaca tcggaactgc ccgaaaaacc tatctgattg aacgcttcag tgatctactg
    65821 gagaatgttg aagaaaagca acaagctgtc tctgaaacag tcacatcaag tgcctctgaa
    65881 caatcctaca tcctaaccga agaaaactgg gaccgcatcc cagccatgat tgggattaca
    65941 gacacagacc tcaaagagat ttttggaaaa tagtgcatca gaaaacccac caattcaggt
    66001 gggttttctg tttattaaga ttattttact gttgctgtgc ttgtgatcaa ttcaacagct
    66061 tttttgatag tgatatcatg tttcaacatg tcagctgaaa gcaagttttg aacttgtgca
    66121 acttccatgt tgtagtctgc tgccaattgc tcaacttctt tttggatttc ttcttctgaa
    66181 gcatcaaatc cttcagcttt ggcaactgct tcgataacaa ggttagtctt agtacgtgac
    66241 tcagcttctg cttggtattg gttgtgaagg tcttcttgag tagttccagt gatttggaag
    66301 tacatgtcag ggttgatccc ttgacgttgc aaattcccaa ggaattcatt tactgaacgg
    66361 tgaacttctt catggatcat ttcttctgga agttctacga tttcagcatt ttctacagct
    66421 gtatcaattg ctgcaccttc aactgcatct ttgtaagctt cttctttagc agcagccaat
    66481 tctttgcggt atttttcttt caagtcagca agtgtttcaa cttcttcatc aatgtctttt
    66541 gcaagttcat cgtcaagagc tggaacttct ttagctttta cttcgtggat agttgtcacg
    66601 aatttagctt ctttacctgc aaggtcttct gcttggtagt cttctgggaa tgttacgata
    66661 acatcaacgg tttcgccagc tgagtgacct accaattggt cttcgaaacc agggatgaat
    66721 tgacctgaac caagtccaag tgagaagttt tcaccttttc cgccgtcaaa ttcaacaccg
    66781 tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt tttcagcagc agcttccttg
    66841 ataaccaatt cagccaggtt gttgcgttcg cgttcgatac gctcttcaac atcagcgtca
    66901 gttacttctt tttctacatc aactgatact tcaaggtttt tgtagtcacc caattttact
    66961 tcaggttttg taacgacttc agcagcgata acccagtctt gacctttttc cattgaagtt
    67021 acgtcaattt ttggttgggc aaccacttca agaccagctt cttttacagc tgcttcataa
    67081 gcgtttggca aaagagcgtt cataacgtct tggtaaagtg attcttcacc aaatttttta
    67141 tcgaagatag gacgtggaag gtgaccttta cggaaacctg gaacattaag agatttcttc
    67201 actgacttga agacacggtc caattctggt ttgatttggt cttgagagat agtgaaagtc
    67261 aagacaccac ggtttgtttc tttgttttca aatgatacag acattctgtc atttctcctt
    67321 aaaatttttt aaatacagtc tattataaca ttttctataa ataaaatcta gactaatgca
    67381 gccaattata gacaacaagc ctttttccta actaaaacac tcataaagta tagacaattt
    67441 tagactactt tggatatctt ttggttagtc attttccaaa actaatttat ctaatttttc
    67501 agttatattt gacttcatct tctcagtaac atgagtataa acacttaaaa tctttgtttc
    67561 attagtataa tctacacgat ccattatcgc tgttataggt acttccaatt cagcaagcaa
    67621 acttatatgc gaatatctaa aaacatgagc agtcaataca aaatcatctt tcttaatttc
    67681 acttttccta aaactgtttt tcaaaaagta attgaaacaa gttatcatta agggagaacc
    67741 attatttgta aatatataat caccttcttc taaaagaaga tattctttta aaatttctaa
    67801 cactctatca ctaataccaa ttactctata tgaagctaaa cttttcggac tatccaaaaa
    67861 tacttcgtta ttggacgatt acattatagt aaaacgaaat aagaacagga caaatcgatc
    67921 aggacagtca aatcaatttc taacaatgtt ttagaagtag aggtgtacta ttatagtttc
    67981 aatctactat acaagacaaa attgaagaaa tctttccatt ataaaacgca tattatcaag
    68041 gtttttaaac acctaataat atgcgttttt tcctatttta aagactttta tccacctatt
    68101 atacaaagtt aagtatccat cacagtttac aattagcctt cattacctaa cccattcacc
    68161 atccttcaag agagtaacct ttaagaaccg aataaataaa tggcaaattt cgttcattta
    68221 atttaactgc actgttaatt tgattagctc catctcctaa agtatgcact cctactacac
    68281 ggtgactagc atcataaact gtagatccac tagacccctc taaagtatca acttggtaat
    68341 ccaagaacat accatcatca cttaaaactt gttttttatc tgtatacatt tgatgaattt
    68401 taaaattata tgatagatag cctgtgatag tcacagttat tcctgtcaaa tttttttgac
    68461 tagtaggaag acccaaagtc cctaattttg caccaatggg ctcttctaga attaataaag
    68521 ccaagtcata ttcccttgca tccttagaat ttaaatttct aaattccttc aaataacgaa
    68581 cttcctttac tttgatcttt ccaaatagtt cttgacttgg actaacagcc ggaagaacat
    68641 aaatatcatc cgcttctttc ccatagtcat gtctgtagta gttgtgagcc gctgtaatta
    68701 acacattatc tttaataaaa ttcgcacttc ccctcccttc tacattcatt ccatcggcta
    68761 ctccataata cttagataaa accatagctg aagtcgaata cggatactgt aaagtattat
    68821 caattttaat caaatcatca ttaccgataa tacttctgat tgcttttggt agtatgaacc
    68881 atacgttggt gaaatctcag ataatgaaga atcattagac tctggacctt tttctagtgt
    68941 ctcacttacc tcatattctt cacctgtact agaaataaca ctcaaagcag atactgtcga
    69001 taactggcta gccaataaag tactcgcaat aattgaaata cccaattttt tataaacagt
    69061 tttcttcatt attgtgtcct cctaatgtaa ttatagcgta ctattctaaa tttcttaatc
    69121 tactatagaa tcaagaaatc taccaccttc tttaaatacc ctccattatc acataaacag
    69181 gtaaactttt caattaatga ctgcgctttt caatcacgct agaggtactt acttgcttct
    69241 ttgatactaa gttcagccat tctttccctg tttttctcaa taaagcatgt tacccaagtg
    69301 ggattcgttt tggagtagtc tcgcagagtc cagccaatgg ctttattgat aaaaaattct
    69361 gtttggttca agttatgaag gagaatcttt tccattaatt gagtattggt cttctctttt
    69421 cttaacaact ggtggtcaat agcgacacgt ctcagccaga tattatctga taggctccat
    69481 tttatactca atgaaaatca aagagcaaac taggaagcta gccgcagatt gctcaaaaca
    69541 ctgttttgag gttgcagata gagctgacgt ggtttgaaga gattttcgaa gagtattaag
    69601 attatttctt ctagttcagg gtgttcatac accaaactcc ctactactcg atctaggata
    69661 tctaccgtgt cccaccagga ttttgtcacg actaactgct ctagcttagg caaatcggtt
    69721 tcctttagat aagactgcat tgctttcaaa tagttagcag ccacatattg gtattttcta
    69781 ggctcctttt cccagcaagt gtctgcaaaa tcccaatcga taatctttgt ttttttcgct
    69841 tctagtaaat atttttatag agtttatttc tttcaggcac cgcaatacct agaaaagaaa
    69901 attgatggcg catataggct tccatggacc ttgctttttt agagtctttt gctgcttcta
    69961 gctcctcaag taaatctgct aaactcatct aaaactcatc ttgccccacc aaatggtgct
    70021 gaaaggcata gacagccgcc tgggtacgat cgctgacttc aagtttggca agaatgttgg
    70081 acacgtgggt cttgaccgtc ttgagagaga taaagaggtc atctgcgatg cgctgatttt
    70141 cgtagccctt ggcgatgagt tggagaacat ctcgctcacg cgcagtcaat tcttcatgaa
    70201 gttccatatg attgcggtgg tattcaacct tcttgctaac ctcttgctca atggccagct
    70261 cgccagcagc taccttactg acggcatgaa gcaattcatc tgcactagaa gtcttgagca
    70321 tatagccttt ggcaccagca tctaagactg gcatgatttt ttcattgtcc aaataagagg
    70381 tcacaatcaa aatcttggct tcaggccatt ctttaaggat tgctaaggtc gcgtcaattc
    70441 cattcatctc aggcatgaca atatccatga caatgacatc tggacgcagt tccaaggcca
    70501 agtcaatccc ttgagacccg ttggacgcct cacccacaac ttctacatcg tcttggaggt
    70561 caaagtagct tttcaagccc aaacggacca tttcatggtc atctactagt aaaattttca
    70621 tctttactcc tttatcattc cttatctaac aggggaatac ggatatcaac tgccagccct
    70681 tgcttgggag ctgttaataa ctgaaccgtc cctgccatat cttcaacccg ctccttgata
    70741 tttcgcagtc cataactcaa gtcgtctaag ctccctaact ggaaaccaat cccattgtcc
    70801 accaccttca gttgcaattc aacatctgtc tgatagaggt agacatctag gcaagatgcc
    70861 tgggcatggc ggagcgtatt gctaatcaac tcttgcagga tacggaagat atgctcctcg
    70921 attttcttag gcaatttcgt catattctgc ttgagactaa ccctaagatc actcttgtcc
    70981 tcaagctctt ttaagagaat ttgaatccct tctatcaagc tcttctgctc cagttcaact
    71041 ggtcgcaaat gcaagagcaa aacccgcaaa tccttctggg ctgtttctaa aatagctgtg
    71101 acactctgca actggatctg catcttttct ctatccaatt tcaaagcctg ctgactgata
    71161 cccgataaaa tcatgtgggc cgcaaacaac tcctgactga ctgtatcgtg caaatcccga
    71221 gcaattcgct tccgttcctt ctcgatgatt tcctcttcct gagcaaggct atgattttca
    71281 gctttttgaa gagcttctgt caaaaggtta agtttacctg ataaggactt gaaactggca
    71341 tccaaatctg gatctgcaac ctgaaccact tcttgccctg ccaataaacg cttgagatta
    71401 gcctgcattt ttcttagaga aagctcttcg atccctcgcc aaaacagggc taagagacag
    71461 gttatggaca tgctgaaaac caacaataaa aagacaaatt tttctgtttt ttcgacatcg
    71521 tgcaaaaaga tagaccagtc aaaatcaagt atttccagca agttgtggga gaaaaaaaag
    71581 acaaacagga aggaggtgag agcaataatg acataggctt gttttttcat cctctaacca
    71641 cctccacatc accaatcata gtggtcaaga aaatcttgac actcttgtta ctcttgagat
    71701 agtcttttgt ttcttgatga tagtgttcat tgcggagggc tcgcttgggc tggttgaaaa
    71761 aagtcaaatc cccatagaga cagttaacgc tgagactgac ttccacatct acaggtacga
    71821 tgattttggt cgttcctacc atctttctga ggataatgac attgtcatga ttggttaaga
    71881 tgaccctctc cagatgaata gtgtccttgc ccatgaagcg aaagagattg atatcatcga
    71941 attggcaagt ctggtagctt gaaaaatgat gaagatttcc aaaccaacga tttttctcct
    72001 tcttaaccgt cacgacctct tcaaaaacca aattggtctg ctctttttcc tggttcatca
    72061 tcgggtaaag aagaaagagg ctatagataa ccgcaacaaa aatagctaga atcacaaaag
    72121 gattgagcat aacgatgaaa aagaagagaa tggttgccgc tactaaaaga agattatttc
    72181 cctctttacc agtgtagtag cgaatcaaaa gcaaaaagag gaatagtatc agcagaaaac
    72241 gcgaaaaatg ctctgatacc atcaaaatca gagctcctgt cagaagacag gcttcgataa
    72301 ataaaaagat tttaaatttt ctcataggtt catcctctcc cttctatttt atcacaattc
    72361 aaaaaagtca cctcagtctg aggatggaaa aaaggcgctg gttacgcctt tttcatctga
    72421 tcctttgctt cttttaattt tccataaaga agatagtcta ctttttgtag atctgctatg
    72481 gtggcacagt taagggaaca cataatcaag cgtaggtctg ctttccagcc ttggacaatg
    72541 ccaatcactt cttcaactgt gtaggtttca accaattcca gaacggttcg tgacaatccc
    72601 acagacttag caccaaaaac caagcactta atcatatcca gcggattccg aacccctcca
    72661 ctaaccaaga gttcgacctt atctttccat tcttgggcat tgagaagggc ctgcatggta
    72721 gactgacccc attgattgag gtaatcacgc tggccactac gacggttttc gatataggca
    72781 aagctggtgc caccacgacc cgataggtcc actgtacgaa caccgaattc ataggctctt
    72841 tcgattgtct tggcatccat tccaaagccc acttccttga ggacaatagg aacgggaatt
    72901 tgctcgctat aatctgctag atgcgattgc cagcttctaa acttcctttc tccctcgggc
    72961 atgagtaatt cctgcatgac attgacatgc acttgcaata gaacaggatt catctcttct
    73021 acagtctgaa gtcctaactc gacaggcttg tccaatccaa tattggttcc aaggaggaga
    73081 ttgggatgac tagacttgac agaaaaagaa tcatccgttg gatttttgag ggctgcgcta
    73141 taagaacccg ttacaaataa aataccacag gattccgcca cctgagccag cttttgattg
    73201 atttctcttc ccttattact tccaccagtc atggcattga tataaaaagg aaagtcccac
    73261 tttcgaccag caaactctgt cgaaagatcg atttcatcca gattgtaaag aggcaaggaa
    73321 gaatgaatca gctccacctc atcaaagcta ttataggaac ttttctgctc aagggcatag
    73381 aggatatgct catccttacg atttgtcgtc atgtcctatc ctttcttgat ataagagctc
    73441 aatccccaga tcggcccaac gattttttaa ggtttcggtt gattgcgcat caaaactcaa
    73501 ggcgatgcca cagtcaccac caccagcacc actactcttg gcaacggcct gcaaatcttg
    73561 actggcttct ttcaactgtc taagcaaagg cgtgtaaata tctgtactca agccttctaa
    73621 aagcttgctg gctacttcta cttgctcgat aactttttcg gctttcccct gctccaaggc
    73681 ttcgaccaaa gaaaccaccg tttcttttga ggaacttaaa aaattttgat tgatattttg
    73741 cttgatttgc tggaccatgt gactcgatac agccacttcc ttggtccatc ccactaagaa
    73801 atcacattct aaagttggtt tcacttgtga gataaaaaat ccccaatcac gctccagaac
    73861 tgtcgccaag ttttcttctt ctaaccaagc agccaccttc tggcgatcaa atgactggta
    73921 gagaaccaaa tcctctgcca caatacaggc aaggtcgccc atggaaccat tgtctcctcg
    73981 cttgagcaag acagcgctag tcagcttgaa caagagattc tgatcaaccg aaagattata
    74041 gagagccagt aaagccttga caaccaagac aacgacgctg ccactagaac ctagaccaaa
    74101 ctttttccct tctcgttcca ttttgccaca gatttttagg gaaaaaggtc ttaaattctg
    74161 accgcgaaca gcgaggaagt ctcccatcaa agcaatcgtt tcttgaatca agctgtagtc
    74221 aggattaggc cttaagtcca ctgcgaaatc aaacatatct gaatagatac ggtagctgtc
    74281 agaaaaagca atttcagccc tcatatagat gggaatatcc tttatcaacg ctaactgccc
    74341 tggctctaaa atagcatatt cacctgccca atagagtttt ccgcaagttt taacagcaat
    74401 catcttgact caaatccttt gtttttgaca caatcaagcg ataacgctga ccgaaaattt
    74461 ctgataaatg ctccaagtct ttctcctgac agaagacctt aacattggga ccagcatcca
    74521 tggtaaagta gcaggcctct cctttctcac gaagctggcg aacaaagtcc atagcctcat
    74581 aagaggcatc cgtcagataa gaaaaggctg gactagcagt ctttgtcgta gcatgcatag
    74641 ccagggcatt tttctccgtt aattctccaa tcttggcaaa atcattttcc ttgagataaa
    74701 tcagcatatc ctgatagtcc ttctcagact gacgaaccca gtcgtcgaaa gtcgtcgagg
    74761 tttccacaca aagtttcatc ccgtcacggc tagagattgg ttttttcttg tcctctagca
    74821 ccaacataat catagctagt ttcaagtctg tctctacagg gtaaatttct ccactatcct
    74881 tatcccaggc tcctagtggt ccataaaaac tccgagaaga agagcctgag gcaaacttgg
    74941 cttcctgcgc taactgactt ctatccaatc caagcttgaa ataagcatta caagccttga
    75001 ccagggcgga caaaccacta gaacttgagg acaggcccgc tgccgtaggc atattgtttt
    75061 gagtatcgat acggacaaag ccctcaccag ctggacgata acggtcaata atcttactca
    75121 tcttggcatg ctcgacctca ttttgtagct gaccattgat gtaaaattcg tcagctgtta
    75181 cattggctgg taaaggcgac aaggtcgtct ctgtatacat attttccaaa gttagagaaa
    75241 tactgctagt agcaggcacc atctcttttt cttttttctt tccccaatat ttgataatag
    75301 caatatttgc gtaggaacgt actgttacag gctctctatc catgtctgaa cagctccttt
    75361 ctcttctaat ctttctgcta gttcttgtgc gtgtgtcaaa ttggttacca aggctatgat
    75421 acaacctcct agcccaccac cgctcatctt ggcacccaga gcaccatggc taagagtcgt
    75481 ttcaaccaaa aagtctgcct cagggctact gactccaatt tcttttaaat gtaaatgcgc
    75541 ttgactgagg atttgtccca gtccttcagc atctttttgt gaaatcgcaa cttctgcttg
    75601 ctgggttaat tctcccaagg catgcaaaaa cggtagggca tccttgccct tattttgaac
    75661 cacttggatg gcttcacgag tatgaccata aacacccgta tcggcaatca ccaaataggc
    75721 ggataaatcc atctcaagtt ctgtaaatcc tacgttcttg ataaagcgaa taggttggtc
    75781 actgagacag gtcttagcat ccaaaccact aggattcata tgggcaatca tttcagctcg
    75841 attgaccaag atttctagta catcatgagg cagatcagcc tgatagtagt caaataccgc
    75901 acgaatggcc gctatgctga tagccgctga cgaacccatc ccccgtttct cagggatagc
    75961 cgagtcaatc tcacaacgaa tgcaggcttc tgtgatatcc aaatactcca gtgaggcata
    76021 aaccgccatg gacaaggtat cctcctcata aaggcgccaa ggactctctg caggaactac
    76081 cttacaggtc acctccacct ccaaaagagg cagggaaatg gcaggataac cgtaaacgac
    76141 cgcatgttcc cctattaaaa ttatcttact atgtgcctga ccgataccaa ctttttttgt
    76201 cattttttcc ttttactaga cgaaaaaacg tcttattttt catacaagta ttaattcttt
    76261 cctatctatt ttattatatt ttcacaaaaa aagcgattgt ttccattcac aatcacttct
    76321 ttcattaccg aacccattca ccattataat tgacagaata gccatctaca gtcgtattca
    76381 ctgccaaggc acctgagcta taagcatagt accagttgcc attgacctgg aaccaacctg
    76441 tcttcatgtc tccattacct gcatttaggt agtaccaagt tgaaccatct tgataccaac
    76501 cagttgccat agctcctgat gaacggagat agtaccattt gttcccaagg ttttgccaac
    76561 ctgttttcat atcgccattt gggtggtcta aataatacca agtggtacct tcctgatacc
    76621 agccagtggc cattgctcct gaggaacgga ggtagtacca cttattacct agatattgcc
    76681 aacctgtttg cataatacca gttgttggat ctaggtagta ccatggagca ggtttgcttc
    76741 tatcaatgtc aatagtaaca tgaaaatctt gagtccaacc cttagcaact tcaccaattg
    76801 gtagtggatt gtaagaatca tcgccaaaat ttcctagctt atttaaataa taccaatgac
    76861 cctcttcata aatccagcct gtctttacag cataattatt atcaaaataa taagttctct
    76921 tttcagcaga tagaggatat tgttcaccgt atacttttcc tgtattttca gacgtttttg
    76981 cctctagtac ttgtttatct gtttgttcta gcaaagcacc atcttgtcca aaatagtacc
    77041 acttctcctg aaggccaatt tcattaactg gttggttatc gaataaatta tcacgataac
    77101 ctgttccagg aatttctaag tattgccaac cgacaaccat ctctccaata tcaccaaaat
    77161 agtaagtttt accgtctatt ttatgccaat agattgcttt atgatcatct tttacataat
    77221 attttctatt atccttatca acaaatcggc cacctgtggt attcgcaaat accgtatttg
    77281 tagctagcaa accaaagaaa aagactgcta gtagaacttg catcattttt ttcaaaagtt
    77341 tcatctatat atcctcctaa aacgattgta gcaaagaccc gactgcatgt caatatataa
    77401 aaactcctca aaaaagcagt tacacaactg caactgctta tctattcttg aatggtatat
    77461 ccaacaccac gcacggtttt aatgtagctt ttttggcctt taacatcaag cttgctccgt
    77521 agatagcgga tatagacatc tacgatattt gtctcggtcg cactttcata cttccaaaca
    77581 ctttccaaca attgctcacg agtcaatact ttcttgcttc ccataagtgt cgccaaaagg
    77641 tcatactcac ggcgggtcag agcaatcatc tcttcaccac gataaaccgt gtgatgttca
    77701 acatctatcc taagattgcg gtaggtcctt ggaactttca tcagactgca gtgttgatca
    77761 atgaagtccc gacctcggaa gatcgccgaa atacgcgcta ccagattttc gataaggact
    77821 ggcttataga tgtatgaaac tgcaaaacgc tgaacaactt ccagctcttc ttgcaagtct
    77881 tcccaatgat ctaaaatcat gatgactgag gcaggtttag ttcggctcaa tttttctgca
    77941 aaatcctgag ccatcatatc tcccagatta acgttcaata aaatcaaatc atagtctgtc
    78001 tgaagagcca tggagagggc tttttgcccc tcctctacca gatcaacccg atactgctct
    78061 ttctggagtt ccaaacttaa aaaatgagct agatttcgtt ctttctcaag taataaaatc
    78121 cgtttcccca tggctgacct acttattttt cgtcatacca agagtagtgg aaggttcctt
    78181 ctttgtcttt acgttggtaa gtgtgggcac caaagtagtc acgttgtgct tggatcaagt
    78241 tagctggaag gtcagctgaa cggtagctat caaagtaagt aatagctgct gagaaagttg
    78301 gcactggcac accagcttga accgcaagag ctacgatatc acgcactgct tgttgatact
    78361 tagcagtaac atccaagaag tattcatcca aaagaaggtt ggcaaggtct gcatcacggt
    78421 tgtaagcatc tgtaatcttt tgcaagaaac gagaacggat gatacagcca tcacgccaga
    78481 tagatgcgat atctgcaaat ggcaagttcc agttgttttc tttagaggct acacgcaatt
    78541 gagcaaatcc ttgtgcgtat gaaatgattt ttgagaagta aagggcttga cggatttttt
    78601 caatcaattc agccttgtct ccttcaaagt tgaaggcggc tggttttgga agcaccttgc
    78661 tagcatgtac acgttcttct ttgtaagttg aaatgtagcg tgcaaacact gactcagtaa
    78721 tcagtgacaa tggtacacca aggtcaagag atgattggct agtccattta ccagttccct
    78781 tgttacctgc agcatcaagg atgtagtcta cgattggtcc atcttggcct tcatcgtctt
    78841 tacggctcaa gatatcagct gtgatttcaa tcaagtagct atccaattca cccttgttcc
    78901 actcagtaaa gatttcagcc atatcctctg cagaaaggcc tagcaagtgt tgcatcaagt
    78961 catagctttc tgcgatcaat tgcatatcac cgtactcgat accgttgtga accattttca
    79021 catagtgacc agctccatca ggaccgatgt aagtcacaca tggtttgcca tcttctggtg
    79081 ctttagctga gatttcttca agaacatccg caaccaattc gtaggcttct ttttgtccac
    79141 caggcatgat agaaggacct tcaagggcac ctttttcacc accagaaacc ccagtaccga
    79201 taaagttgat accagagttt gccaattctt cattacgacg gatggtatct ttgtagaaag
    79261 tatttcctcc gtcaatcaag atatcaccct tgtcaaggtg tggaagaagg gcttggatag
    79321 tagcatctgt accaggtcca gcttgaacca tcagcatgat acgacgaggt ttttcgattg
    79381 agtttacaaa actttcaacg tcatagcttg gtacaaagtt cttttcagga tggcaagcaa
    79441 tcacatcttc cgttttttct ttactacggt tgtagatagc aactgtgtaa ccacgagatt
    79501 caatattaag ggcaaggtta cgacccatta cggccatacc tacgacacca aagttagctt
    79561 ttgtcatttg acactcctct tgtttcattt gttttatttt atcattttta cttttgaaaa
    79621 gaaagaattt tgtaacgact gcttagtagt ccaagtcatc cgcatgacca gcgccatttc
    79681 cgacaaagta gcctgtctta cagttaaggg taaagagata ggttccatct ggcttataga
    79741 ggttgtaata accattgccg ttaacgatat tgacacgttc aaggatatat tggtctccag
    79801 tgatatagcc acgtgaacgt gaagtcgcta gaatttgttc caagacacca tccgcaaaat
    79861 cccaggcaga gttattacta tcatcaatag cagactgatt ataggcaaca cgactggcac
    79921 ttctttgaac agcaacccct gcactcgaga gacccatatt gacttcactg cgactacttc
    79981 tagtctcatt tgaactactt ggttttggct cactagtcgt atttgaactt gcttgacttg
    80041 aacttgagct gctagtttga cttgaacttg agctagaagt acttgtttgc tggctcttac
    80101 caagactgat agccttatct agcactttat caagctccgt atttccagtt ttaatatccg
    80161 taaatttagc atccgatttg gctttggcat tggtatccaa cacaccatcc acaatagctg
    80221 gtttctcaaa ttgagcattg acatcttgaa tagccttgat ttgcgttgct agactatcat
    80281 atttagattt ggcaagcgta tgttcacgac taccttccag cttatcaagt aaagtcttga
    80341 gttgactcag tttatcaaac tggctatttt tcaaagccgt tttattgcta tctgtgtaaa
    80401 aggcgtcata aagtgtatta aaatcatcca catccgattg attggctgta gttgattgag
    80461 aagtttcaat ttccttagtc gaacgagcca cttgacggta gacataataa gcactgacac
    80521 aaataattac tgatacaagc gccaaaacgg tcaaaataaa gcctttttta cttttctttt
    80581 ctgagtcctc ttgatccaga cgagaaaggt tttgctcctc ttccacttct tcagtcattt
    80641 ctgttggatt ttcatcctct agcaatagag gatccaagcc ttgctcctca tcgtccagag
    80701 gcaagggtag taagatgtct tcagaaaatg gaacttcctc cgaagaagct tctgacttct
    80761 ctacagcctc acgcatctct tgaattaaat catccagact ctgagtttca acgaactcct
    80821 cttttttgta ttgacgagtc gcaaacttat ccgcctcaat ttcatctctg tgttgcttaa
    80881 catacttgtc caaaatggaa tcctcaggca agactcctgc ttccacttct tcatttttac
    80941 gaatagcttg accaactgtt agctcttttg cttcatcaaa atcaaattgc ggttcttgac
    81001 cttctttttt atgacgattt cgtctttttt tactcatgag tatccctttc tattttacct
    81061 cttgccgttt gacacgctga ccaaaatatt gatatagatc cactttcaag gttccgttgt
    81121 ataacttacg cttcttatct gcttggctac catacttgct ttcaaaagct tcatcactag
    81181 tcaggataaa tttgctccaa gttttcagcg gtgcaaatac ttgccccatc tcagcataga
    81241 gcttagtcac ccctgcatca tctgacaaac gttcaccata aggcggattg gaaatgatta
    81301 ctccattgat tttatcggaa cgtaaatcct gcacgcgcat ctgcttaaaa gtaatgtctc
    81361 ctgcaacacc agctacctga gcattggcct tagcaatttc caccacgcga gcatcaatat
    81421 cacagcccat gatatccagc tcaagctcac ggtctacttt tttagccgct tctgtgcgca
    81481 cttcttgaat caagcgatcg ctgatccagt tccattcctc aaatgcaaaa gagcgacgaa
    81541 gacctggcgc catctttcta gcaatcataa ctgcctcaat acagaaagtc cccgaaccac
    81601 aggtcggatc aatcaaaggc ttgtctggat accagttaga aagttgtaaa atggctgctg
    81661 ccatattttc cttgatagga gcgccacctt tttcggtacg ataaccacgt ttaaagaggc
    81721 tagacccggt cgtatcaatc atgacagttg ccacatcttt gagaatagag acctcaatct
    81781 taaactctgg gccattctcc atcagaggaa ccccttctgg gcgagcatag tgtttctgca
    81841 atttcttgac aacagctttc ttagaaatag cctgaacact gggctcattg tgaagtttgg
    81901 acttaacaca tttagctttt gaaatcggga accgagctcc aagtggtaaa taattttccc
    81961 aatccaaagc gaaaactccc tgaaatagct cttcaaaagt cttagctggg aacgttccta
    82021 cgataatttt gatacgatct gctgcccgaa gccaaaggtt ggtttcgata atagctctca
    82081 cgtctccttg aaaacgaaca cgtccatttt caacctgaca atcgtagccc aactctcgca
    82141 cttcacgacc aacgacagcc tcaagccctg ctgccacagt tgcaattaaa ttaaattctt
    82201 ttttcatgtt acagtcttgc aagacctttc tatatgtcca ctttaaaaaa tgaggttgag
    82261 aaaatttctc agccccaacc tatatgcaat tttctataag ccatgttttg ttccagaagt
    82321 gactaggacc acttccttcg ataatcatct gtctaccact aacagctcta gctgatagca
    82381 gtcagaatac tacgttcgtt tccgcgtact ccatgccccg accaaaattt gggttgctag
    82441 cttgaggggt ttaccgcgtt ccactctctc tgtttccaga aagactccgt cactgtggca
    82501 ctttcaagcc tactctggcc tatccaagga cttagccatt tcaactgccg taacgatttc
    82561 tcgtccctag gcttatggtt tcgcctagca caaacactac aggcatcaca gcctgtgcta
    82621 gcatggactt tcctcatgag aagcaattct cctcacgcga ttatccaaaa attgcacatc
    82681 tcaaataact acttaaaaat ctgagttatc taaaatttgt ttaccaaaaa cttctttttc
    82741 caatctattc aggcgtttca aaatatcaaa attcgtcata gaacttgtaa ttgccgcttc
    82801 aaggggttct gcttgaactg gtgaaggttt cggtttacga gttaattctt ccttcaaatc
    82861 cgcaatttcc tgacgaagtg acttgaccaa ggcagcatag gtttcatagt ccttgatgac
    82921 atcgtctaaa aactcgtcaa cttctacttt attatagcca cggacttcac gtccaaactc
    82981 ttgttcaaaa atatctttcg ctgaaaaaat aatacttgcc atgtctctct ccattctcgc
    83041 ttgctagtat tattatataa aaaaaggcaa acaaaaatca aggtcaaagc ttcaattttc
    83101 ggaaaaattt tcagcaagtt catttaattg atcaaatgtt aatctcttta taaaatagtc
    83161 ctcttgattt ttcatctttt ggtaaaaata agctagtttt gtttcatttt cttcatcata
    83221 aaaaagatag gaactagtcg tgttttccag caaaaactgc tggtaatctc ttaactgccc
    83281 cttgtgttca tagcgaggat aggcatattt gacaaagtct acctgcttaa agcgactcag
    83341 tttcatctga ttgccttcat tccaattttc cccatgggtt tcaaaagcaa aaatggtggc
    83401 caactggaaa ccgtattcag ttttcatctc ctgagcaacc tctaaaaccc aatattcaaa
    83461 acccaaactc cctgtaaaca caagccaaga caccccatct gctgccatag cctctaaatc
    83521 tttacgtatc gcttttttaa tcaatttaag acgaggatcc ttatcagaaa ataaacccaa
    83581 atcaaaagca gaatagccta aaaccaaagc tgtagccatt tttaaccctt tctgtgcaaa
    83641 ttatggtata ataaagtgat gttattgtac caataaggag aattatggtc aactatccac
    83701 ataaagtttc atcacaaaaa agacaaacat ctctttctca acccaaaaat ttcgcaaatc
    83761 gaggaatgtc ttttgaaaag atgatcaatg ctaccaacga ctactatttg tctcagggct
    83821 tggctgttat acataagaaa ccaactccta ttcaaatcgt acaagtggac tatccacaac
    83881 gaagtcgtgc caagattgtt gaagcctatt ttcgacaagc ttcaacgacg gactattctg
    83941 gcgtttataa tggatattac atcgactttg aagtcaagga aacaaaacaa aaacgtgcga
    84001 ttccgatgaa aaattttcat ccacatcaga ttcagcatat ggaacaagtc cttgcccaac
    84061 aaggaatctg ctttgtcctt cttcactttt cttctcagca agaaacctac ttattgccgg
    84121 cattcgattt gattcgcttc tatcatcaag ataagggaca aaaatcaatg ccacttgaat
    84181 atattcgaga atatggatat gaaatcaagg ctggtgcctt ccctcaaatt ccttatctca
    84241 atgttatcaa agaacattta ttaggtggta aaacaagatg aacaaaccaa cgattctgcg
    84301 cctaatcaag tatctgagca ttagcttctt aagcttggtt atcgcagcca ttgtcttagg
    84361 cggaggagtt tttttctact acgttagcaa ggctcctagc ctatccgaga gtaaactagt
    84421 tgcaacaact tctagtaaaa tctacgacaa taaaaatcaa ctcattgctg acttgggttc
    84481 tgaacgccgc gtcaatgccc aagctaatga tattcccaca gatttggtta aggcaatcgt
    84541 ttctatcgaa gaccatcgct tcttcgacca cagggggatt gataccatcc gtatcctggg
    84601 agctttcttg cgcaatctgc aaagcaattc cctccaaggt ggatcaactc tcacccaaca
    84661 gttgattaag ttgacttact tttcaacttc gacttccgac cagactattt ctcgtaaggc
    84721 tcaggaagct tggttagcga ttcagttaga acaaaaagca accaagcaag aaatcttgac
    84781 ctactatata aataaggtct acatgtctaa tgggaactat ggaatgcaga cagcagctca
    84841 aaactactat ggtaaagacc tcaataattt aagtttacct cagttagcct tgctggctgg
    84901 aatgcctcag gcaccaaacc aatatgaccc ctattcacat ccagaagcag cccaagaccg
    84961 ccgaaacttg gtcttatctg aaatgaaaaa tcaaggctac atctctgctg aacagtatga
    85021 gaaagcagtc aatacaccaa ttactgatgg actacaaagt ctcaaatcag caagtaatta
    85081 ccctgcttac atggataatt acctcaagga agtcatcaat caagttgaag aagaaacagg
    85141 ctataacctg ctcacaactg ggatggatgt ctacacaaat gtagaccaag aagctcaaaa
    85201 acatctgtgg gatatttaca atacagacga atacgttgcc tatccagacg atgaattgca
    85261 agtcgcttct accattgttg atgtttctaa cggtaaagtc attgcccagc taggagcacg
    85321 ccatcagtca agtaatgttt ccttcggaat taaccaagca gtagaaacaa accgcgactg
    85381 gggatcaact atgaaaccga tcacagacta tgctcctgcc ttggagtacg gtatctacga
    85441 ttcaactgct actatcgttc acgatgagcc ctataactac cctgggacaa atacccctgt
    85501 ttataactgg gataggggct actttggcaa catcaccttg caatacgccc tgcaacaatc
    85561 gcgaaacgtc ccagccgtgg aaactctaaa caaggtcgga ctcaaccgcg ccaagacttt
    85621 cctaaatggt ctcggaatcg actacccaag tattcactac tcaaatgcca tttcaagtaa
    85681 cacaaccgaa tcagacaaaa aatatggagc aagtagtgaa aagatggctg ctgcttacgc
    85741 tgcctttgca aatggtggaa cttactataa accaatgtat atccataaag tcgtctttag
    85801 tgatgggagt gaaaaagagt tctctaatgt cggaactcgt gccatgaagg aaacgacagc
    85861 ctatatgatg accgacatga tgaaaacagt cttgagttat ggaactggac gaaatgccta
    85921 tcttgcttgg ctccctcagg ctggtaaaac aggaacctct aactatacag acgaggaaat
    85981 tgaaaaccac atcaagacct ctcaatttgt agcacctgat gaactatttg ctggctatac
    86041 gcgtaaatat tcaatggctg tatggacagg ctattctaac cgtctgacac cacttgtagg
    86101 caatggcctt acggtcgctg ccaaagttta ccgctctatg atgacctacc tgtctgaagg
    86161 aagcaatcca gaggattgga atataccaga ggggctctac agaaatggag aattcgtatt
    86221 taaaaatggt gctcgttcta cgtggagctc acctgctcca caacaacccc catcaactga
    86281 aagttcaagc tcatcatcag atagttcaac ttcacagtct agctcaacca ctccaagcac
    86341 aaataatagt acgactacca atcctaacaa taatacgcaa caatcaaata caacccctga
    86401 tcaacaaaat cagaatcctc aaccagcaca accataacat ttatcatcca gatttttctg
    86461 ggtgattttt tcatagcact attgtattta tgtgcttaac aaaagcctga gaagacatct
    86521 tctcaggctt tttctgtact ataaacctca ttggaaaaga tagagactgc ttccgtaatc
    86581 ttgttaagag gttttactaa atactagtct ttcttcgttt ttactacaaa gagagcagat
    86641 agggctaggc taacacctgc taggaagagg gctgtgtcag attgactctc acctgttgct
    86701 ggtaagattt gttcaggtgt ttctggtcta tctatttctt gcttataatc tggcgtctta
    86761 ccttgttcgg aagctaaaga gctaagttta aactcaggtt tctctacagt tggagcatct
    86821 gatttcgtag cagaatcttt taattggttg agataatctg caaagtattc caccattctt
    86881 tccgtcaaga gatggttatc cgtcgcatat ttcatgcttg cctgaacgct agctacttcc
    86941 tcttgattgt ctttatctgt taatttctga gccttagcca aagctgcttc atagcctgac
    87001 aagtcaagag gtgtttctgc tacctgtgga cgagtaaaga taagttccgc tgcagattgg
    87061 tatttatcgc caccatctcc gtaagtctta gtacctgtaa ggacaatttt cttagcctta
    87121 attgtcttac caaaatcaat gtcttttggc ttattgttat ctggccaatc agttgcagta
    87181 aaggtatgct ccttgccaga ctcagctgtc acaacaagtt tcacatcacg caaattacca
    87241 tttgaacctg atccacgtgg aacataacga agtccagtga tttcagttgc ttctttcaag
    87301 accatggttg caggcttgcc tacatctcct ccgccccatg atgtatgcca taaactagat
    87361 aagtttccat caaaggcatt tgcaagacct tcttgagcct gagcaggagc tgtaagactt
    87421 gcaaagtcat ctgctaccaa agccgttttc ttctgaacca aagcattctt caaggcttca
    87481 atcttagcaa tctctgcacg cgcttcttcc acactgatat catcatcggc ctgactgagg
    87541 ttaaagaccg cctctttcaa agcatccata gactctttgg tgtagttagt catggcaacc
    87601 gttggcaagt agttcttcag agcattttct gtcaacatct tacctgttag ggtaatttct
    87661 tcgatttgaa gattatccat catgaagtcg ttataaccac ggaagttggc atttccacca
    87721 gaatcaccac gagtattact tgcatttcca gttgagtaga tacctaccca agtatcccct
    87781 gtttctgcac ctgtcacgag gaaggttgcc ttcttggctt tcttagaatc tgtccaagta
    87841 tttggcaatt catgcatttc caagttgctt gcttgagtac cacgacgacc tgactggaat
    87901 tctcccttac cgactacaaa agcataggta ttgtctgatc ctgcttcgta ttcaaaggtt
    87961 acacggtagg tcttacctgc ttcaaaacgg aagttttgtg ggatggtttg gtaaaccaag
    88021 ttacgacggc tcactagtcc atttgtcttg agtgaccaat ttccttcgat aacatcatcg
    88081 actttcttac cattccaacc acgttgtgta tatggatcgt gtttttcaga caagtgagtg
    88141 cggttatctt caacaccttc aacaccaccc actacaaatg ggaagatacc ctgagcaaca
    88201 ttttcaaagt cttgcttgaa ggtgccttta cctgtatcat gcttgtctcc gtacatgctt
    88261 gaattgtttt caaaggtacg aatttcatca aagtaagttg cttgatcacc agcttcacga
    88321 ctcaatgtca gagtaacatt tgagacgtcc gatccagttg taaagaaggc gtacatgttt
    88381 tggaagtaac ttgtatcgtc aactgtagca ttgttacgac gtgtattgtg ggcgtaggct
    88441 tttacatagt tgagggcgag agacttattg gtataagtag tcacttcttt ttcaccagta
    88501 ttcacagtga tacttgcctt ggcattacta cggttatcga caccgacata aacggcatac
    88561 ttggtatttg gtttcaagcc agttaatttc tgagtgagac taactttttc tttgtttcct
    88621 tgaatacgaa gcatatcgtt tgccccttga gacttgacaa tttctgcctt agaagcatcg
    88681 cctgaaatgg tccagtgttt caaggttcca ctattaaatc cttggtcata gatgtgcatg
    88741 ccttcactcc atgacatttc aggattggtt tgttttgaac ggtaaagtac gtatggttga
    88801 tttgctagaa gatctagggt aattttacca tcttttacag ttagttcttg ctcttctgtc
    88861 ttaccttggt cagttagctt gtaaaggtaa accttgctct ttgcccaatc gcttggaagg
    88921 gtccaagttg ttgcaccagc ctgcgtattg aagtagtaca ttttttcctt atcagtagaa
    88981 agtttcttac catttgcatc ccagttccaa ggagtcaagt aagctgaact atcttggatg
    89041 acacgtccgt tgagcgttac tgtacgttcg cgatattgtg ggctattgac atcatttgac
    89101 ttacgagtta caactacttt attattgtca gcatctacca attccactcg catttctgga
    89161 gtccatttat aggtgctacc gttatcggtc atagtcaccg gtgtaccatt ttcccatttg
    89221 cttacagtga agtgttggaa atacttggtc atgacgtcat gggcaaataa gttggttaca
    89281 tagccattgt agtcacttct tccttgccag ccttcaaagt ctttcatgct gtagccacct
    89341 agcagtggat agttggctgc accaccataa cttctgtagt ccccaaccca agcatctttt
    89401 tggtggttac ggataaagcg ggtgatggca ctgttgatac ctttattggt gtagccaccg
    89461 taggtcaagt cagctgccca gtgatggaag gtagagtcgt actcaccacc atggccccac
    89521 tcgatcgcaa agcgccagtc ttgtttgtta atttctttag caagaacgtg ggtagcccag
    89581 gcaccgttat cacctgattg accattaccc caaacgtcca catagataaa gtcaagaccg
    89641 tcaccaagtt ttttcttcaa atcttcccaa cgtgccaaac gaccatgagc taggtcatag
    89701 gcagcatcaa tgttgatacc ttgatctagc cagttccaac catagctata gcttccatct
    89761 ggattcttac ggagaatttt ttcattgaag tatttagact caggataagt ttctgaagcg
    89821 ttaacgtgga tacctagatg agctccatat ttcttagcct tctcaattag ggtcttgaag
    89881 tcttcgacac caccgatacg cttaccaata tcagcatagt tcaagtgacc agagtcatgg
    89941 ccttcgctac catatccttt aaggagaaca ccttgcccaa gaccatctgt atggagattg
    90001 attttcttga taccatccaa ggtcataagg aatggatttt gtgcttgaga accaaagttc
    90061 atcgcgatac ggtaagctgt gatatcctta actttttccc aaccttgagg gttgttcata
    90121 atgctacgat aagcaatggc accatcttgc caatcaactt tcttgtctgc attggcatct
    90181 tcagtgataa caaccttagc acttggaagt tccttcgtgt attctgggaa aacaatgccc
    90241 ttataagctt tttcccattg ccattcagag ctgtggattc ctacatagtt ggcatttccg
    90301 actgtttctt tataagctgt caaacgagtc cagtcattcg aaccaccacc atagctgttt
    90361 tgagagttac tccaaacacc agcagcaagc ttatctgtag aaacaaatcc atacatgtaa
    90421 cccttagcca aatccttcat tggattggtt acatcgatat gatcatctcc gctgacatgt
    90481 gtattgtttg acatggttgc cccatcaaac ttagcaccag tttgatcact agaaacagag
    90541 actaaagcat tgccgaggaa actaatagaa gaaagtagtt ttctttcgtc atcaatcttt
    90601 tgacctggag tgacttgatt gtggttgaca atcttggtca catcaaaatg caattgattg
    90661 tccacaactt gcaagcgtac tgtcatttcc gcattgatta agtgagcatc atcgcgaatc
    90721 ttcatcaagt actctgctgt tgtctcattg attttcttat aagtgacttc aggggtgatt
    90781 cggtggttat tgataaagac ttggttgaac tgttgcacct gtcctggcaa agtatgtcca
    90841 ttcaagctgt attccttgac acgagggaag gcttggtcaa tcactgcttt gagggcctta
    90901 gactgaatcg tgtcataagt caccttgcta tcatcaactt caggacctgt ttctttttca
    90961 gcaggggtat cctctgtttt taccccctct tggttatctg ttctaacact aacaactgtt
    91021 cgctcatcgt cataagagcc cgccttgaga aaaatcttct tctcattttt aagatggtca
    91081 ttgaccgcag ctggtagagt cactgtgtca aagagattga catcgttatt gctggcattt
    91141 agctgaccgt ctgacttgag agtgatagag agacggtttg ttgatcctgt ttcaggagca
    91201 gcaacacggt tgcctttata ccatgtgcta ttacctggag ttttgtattc ccagaaccag
    91261 ccatccttgt cataaccgac aaaaacatta ttcttggtat ctttaaattt caagaagaca
    91321 ccaaagcgtg atttgccctt ttcagaatca tctttgaagg ttaaatcaac agttgcattt
    91381 ccattggcat caacggtcaa gcccttcttt tcaaacaggg ctggtttacc tgcgttatca
    91441 ttttgagcag ttgaggatag ttggttgtag cggacacctt tttcttctcg gatagtgact
    91501 gttccctgtt gttctttttt ctctaccgtt tgccattcag gggttaccgt cttaggtgtt
    91561 tcaggtttag cagctgcagg tttatcctct tttggttttt cttcagccgg tttttctttt
    91621 tcaagtgcta atagttcttc ttctgtctta ggtccatctg taacttctgg agaaccttgg
    91681 tcttctccca ccttaggcgc ttcaaaatca cgcccatcat tctcttttgc tgttgcaaga
    91741 gcagtagcta aatcagctgg taagttcgcc gtggaaccag actgcacgct atctgcaaga
    91801 accggacttg tcccaaagaa tgcagctcca atcataacag aagcaacacc taatgaaaat
    91861 ttccgaatac tatatttaca acgtttttca aataatcctt tattcataaa cttctaaatc
    91921 ctttcatttt tgggcaagcg tttacatttc ctttttaaaa aatactcctt cctctgaaag
    91981 tgcaatgctt aaccctgata aataaaaaat agttatactt ttaatataac aaataataac
    92041 tgataaagca ataggaaaca agtaaaatta acaaaaattt tctctattct gacaaaaaga
    92101 ggctccaact tttggggggc agtacattta gaatctttct ttacaaatgt aaaaaaggat
    92161 tcagcattca agagaaatac taaatccttt cttatatttt gcaacagtta tttcacatgt
    92221 tttgcgagat cttcttgagc ctttttatta gactcttctt tttctttcat ccatttttcc
    92281 tgagcttttt ggtattcatc tacagtgact gccttgtctt gaagttccaa gtatttatac
    92341 aagactggtt cacttgtacc tttatttcct gacaatgcaa atggtattgt aaatggtacc
    92401 atcttagaca aaattggacg ccctgtacga gatgtagttg gaataatcaa agcactatct
    92461 gtcaaccaag cttgggctgc agcgtattta tcatagcgtt tagcaacatc tgtagcctca
    92521 tcaccagcct cagtaaccaa tttttcgtag tcatatagac ctactttttt agcagctaca
    92581 ttatcttccc ctgagtcaaa ccctaaatat gttttagtac tttctcctac agatggtttg
    92641 atgatatcaa ggtaggttga tggatcggca aagtctggac cccaaccgac attatctgat
    92701 aaatcccagt cttcgccagc agcattttca gcaaaatatg taatattgtt tacttcgtct
    92761 ttttgtagtt gttgaatatc aatgactaca ttatccgctc ctaaagttgc ttccaaggat
    92821 tgtttcatag attggacgcg ctgaactttt gtagttgctg tttggtcaac tggcatatcc
    92881 aaatgaattg ggaatgtcac accttctgct tgtaaggctg atttagcttt agcaaattca
    92941 gccttggctt tttctggatt gtaaagacca tcctgagaat ctgcaagatt aacatccttc
    93001 cattcatccc cataagtaac caatttctct ttgaccatat cgccaaagtt tttaccatct
    93061 gcttgaacaa atgttggtgg aacaaagata ttacgtaaga ttttgcttgc tccagtttgt
    93121 ccattcaact gagaggcata ggctgtacga tcaaaaccaa aggcaatagc ctgacggaaa
    93181 tccttgttta agagagcctt tttagtcgat gccttttgtt cgtcgctggt cttagatgtg
    93241 tatttatagg actgacggtc aatatttgta ccaactagat acgtaataga gtcttgttga
    93301 gtatagacaa tattgtcctt catactcttc tcaagctctg cgaaacttgc acttgttgga
    93361 tagagacgag ctgctgtaag gctaccatct ttaaagtttt ctgcaggttt gctggtatct
    93421 tgaccatccc agaatgacaa tttaactttg tcaatatgca cattgtcctt atcccagtag
    93481 ttcggatttt tcgcaaattc aacagaagat ttggtcacaa tggatttcaa caaataagga
    93541 ccgttataca agagactgct tggatccgta gctttggcaa aatcatcccc ttttgaattc
    93601 aaaaactctt cattaactgg cgcaagcaca cccatggttg tcttagaatt ccagaagctt
    93661 tctggtttgt tcaaagtgta ctgaactgtc tgttcatcca gagccttaat tcctacttgt
    93721 gagaaatctt tgatttcccc ttttacatag gcatccaacc ctttgattga ttcttgaaca
    93781 aggtaaagag catctgattt tttatcagca gcatatttta gtcctgttac aaagtcttga
    93841 gctttgactg ccgcgtattc ttcaccttca gaagtatacc attttgcatc cttacggata
    93901 gtataagtgt aagtcaatcc atccttggat acagaccaat cctcagccat agacggcaca
    93961 aagttcccgt agcgatcatt ttctagcaaa ccatcaacca cgttactggt aatatttgct
    94021 gtcgcagcct tagcagttgt caaatagttg aggttatcag ggtctgtctc ataaatgtat
    94081 gagaatgtct tctcaccttt agtgcttgaa cctgatccag agcatgcagc taaagtagtc
    94141 gccgccaata atgtcacgcc cgcaagagca aatagttttg aacttttcat cattttctcc
    94201 tttaaaactt tctctccatt atagactctt ttcagaaaga tgtcaacaga attttcagaa
    94261 tttttgaaaa ttatttttca aacaacattt ttgcaaaaaa tatgaatatc attgtaaccg
    94321 cccaataacg aagtctattg aaaaatctcc agactagaga actcatatat agttcctaat
    94381 ctggagattt cttatttgca cttttcttgt acaactttag tccatggtaa ataagcctct
    94441 aaaacctctt tgtttacgag agtttcctcg tttggaagac attctagaag atagaataga
    94501 tatttctcgc tatgaaggct cagacgattg tcacaagtca agggagaatt atttctttgg
    94561 atatcactgt gaactatagt catgatatga agttgttcaa aatgagtcgc agaaatatcg
    94621 gacaagctgg taaaatcttg gctgacagtg gttatcaagg gcttatgaag atatatcctc
    94681 aagcacaaac tccacgtaaa tccagcaaac tcaagccgct aacagctgaa gataaagcct
    94741 gtaaccatgc actatctacg gagagaagca aggttgagaa catctttgcc aaagtaaaaa
    94801 cgtttaaaat gttttcaaca acttatcgaa atcatcgtaa acgcttcgga ttacgaatga
    94861 atttgattgc tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata
    94921 ataaaatcaa tttaaataca tacgagtatt ttgacagtat tcatgaattc actattcaga
    94981 atgaaaaaat cagacaattc ctttccacat ttctttcacg tttttaaatg tataagtcgg
    95041 ttttatacta ccttgttgaa tatcattcac cgttgcttct cctgtcagca cacaaactga
    95101 agttactcct gcatttatac cagtcatgat atccgtatac aagcgatctc caatcacaac
    95161 tgtttcaaat agagaataat ttaatttttt tcgaacaata tcaaccatcg taggttcagg
    95221 tttacctatg taaacaggtt tcctatcgac tgatttacta atcatatcac aaatagaacc
    95281 acaatctggg atgaatccaa acgatactgg gcagcgaata tcagggttag tagctatgaa
    95341 aggtacgtcc tttgttgata gaatctcgca ggtattgcga attttatcac tggttaattc
    95401 tgtatcaaaa ccaacaagaa caacatctat atcagcacta acttgctcag ttacatcaat
    95461 tcctgcgtca gatagttctt ttatcaaaga ttttgttcct tggcaataaa ctttagattt
    95521 aggataattt tctttaatat aaacaattgt ggcttgagca gaggtaaaaa aattatctcg
    95581 ttcagcttta atacctaatc tgttaacttt ttcaacatag tcaacaacag acttagatga
    95641 attgtttgta ataaaaatat actcaccgcc aatattatga atatagtcta ataattcgag
    95701 agtaccctca aacaatctat cttcttcata aatggtacca tccatatcaa ataagaataa
    95761 ttttttattc tgaagttcac taatatcagc accaaaataa tcaactctat ttgtcaattt
    95821 cattctccat attcggttta agcaaatagt ttttctgcaa cagctaggtc ttcatgatta
    95881 tcaatttcta accaacggcc atccaatgga catgctataa actcaacttc tggaaggatt
    95941 gcattaagag caacctcact ccacatttga agttctcgtt tatcttcaat aaattcctta
    96001 cacttttcaa agaatcgagc acctgcttca taagagaatt tataaacatc aatagaagcc
    96061 cctaaagcct cctcaggtga aatctgttta gaaatttcca ctaaacgccc atttttttct
    96121 acgactttca tagactcttc aatataagta cctaaatcag ttacaattgc atttggagct
    96181 ttatgaagca acagactttt aataacagaa gcatcataaa atacatctgc attcatcatt
    96241 aagaagtcac tatcacccat tgcagctttt cctagatagg ctgaatacat attattagtc
    96301 gttttaaaat caacattatc aataatatta atttctggat acttttcagt aactgcatct
    96361 gttaatacag atgacttata tccagcaata atcgtaatat ctgtaatatt attttgatat
    96421 aaattttcaa tttgtttcat caaaattggc ttaccattga ctggtaccaa agattttggt
    96481 acctcattgg taattggggc tagacgtgtt cctaaccctg ctgctaaaat aagtgctttc
    96541 atttttttct ctcttttcta caactcgctt atgagttcct tatatatttg tttcaatcta
    96601 tctgtactaa gatcaacctc atgcagataa gtatagcgat tacttctcat ttttgtagca
    96661 tgttgcatac aataaataaa caactcttca tctatcccca aaagtttcgg gttaatatga
    96721 acctcaaatc tttgcaagta atccaccaca gcatcaacag aattttcaat taatttcaaa
    96781 actgcgactg tacctaatgc aacctgaatt ccatgaagat tccttgtaga accatagtaa
    96841 tctaatgcat gactaaataa gtgctctgac ccactgacag gtctactact tcccgcaaaa
    96901 tccattgcaa tgcctgataa aactaaagag tttaccaaaa cttcaataaa atcaggggta
    96961 atagaattat acttcgtttt cattaaagca tctaaagaat tttgcgacat tagatatgca
    97021 aaaccatgca tctcatcttt ccctcgctca actgccaact cccaatcttt caatgcagtg
    97081 taattggata ttgtatcacc gataccagct tttatgtttt gtataggtcc tgatgcaata
    97141 acatcaatat caattagtgt cattgagggg atagccgccc ctaagctttt tggtctatca
    97201 tcctgccttt tcaaaacagc aactggggaa gcaatgccat catttgctgc tgttgtcgga
    97261 atcgataggt aaggacgttt cgaaataaaa gatgcatact tgcagacatc taaaacacga
    97321 cctcctccca ttcccacaat acagtcaata tctgtggcaa tagccctttc tgctatattc
    97381 atcgcataag caatagtatt ataattgcaa ctttcttcct ttacccgacc aatttcctct
    97441 atttgtgaac gtactatcga accgtacaag tcatcgacaa ctggatcagc acaatataaa
    97501 atctttcccg aaatattatt ttgagaaagt gtagcggaga tttgatgaat agctccactt
    97561 cctatcttta aatcattatt tttcaaatct cgttacctta aaaataaccc aatgttttac
    97621 ttcacaactc ttgaattatt ctccttccta cattttcact agcggttcca ttaaagattg
    97681 gacacagtat ttcatttcta tattttttta tagaatcata atcaaaattt tctatttttt
    97741 taggcagtaa gtcatacaat tcttcagcag ttttaatgat agggtccggc aattcgtaat
    97801 atgtatctga tagtccccta agctcagcat atttttctaa atcattcaca tatctgacat
    97861 aaggcttgtt taaaagcata aaatcaaata tcgcggaaga ataatctgtc agtaaaacat
    97921 ctgccaataa tataagttcc tgcatatctg agaatagcgt aacatcaatt atgtcatgat
    97981 taaaagaaat attattacta aaatgagagt cattaggatg taatctaatt aaaattttac
    98041 atttcttctt aatttcttgt tcaatacttt gcaaaagccg ttcaaaattt atatctaaat
    98101 aagatgcatc cccatcatct ctgaaagtag gggcatataa aataacataa tcatctgaat
    98161 caatgcttag ttcttttctg atattattta acttgtcgta gtcttcctta tagtgaaaca
    98221 aggcatcatt tctcggcatc cccacctcaa aaatttctcc tgaataccaa aaatactttt
    98281 gaaattcttc agtttgtttt ctgctatctg aaatcattat atctgtgact cttgcatcat
    98341 actttgcttc taaaatatat tttaatggta aatcagcctg cttttctatc agtttaaaac
    98401 tagaagcacc gtgccaagtt tgaatataaa actgtccgcg tttttttagt agtctttcaa
    98461 aatttcttac attataaacc caaaccttcg aactagcttg ctcataaaaa gattgtagag
    98521 atttatatct tacaactctc actccatctg gaaaatcttc attatctttt gcaagccaaa
    98581 ctaaatctaa ctctggatat gtaactcgaa gatactcaca aatacttttc ggattatcac
    98641 catatccctt accattaaaa ttaataaata gtatcttatt cttctttatc cgaacaggcc
    98701 ataacactat actgataata accataaaaa caactcttac taaaaattta acattttgta
    98761 aaacaaccat cttaactaaa cctttttaat agtctgtttt tgataaattg aaatagaacc
    98821 cctagaaaac aacatatcaa aaagacaaat atcgtcccaa atttgagaat ataaacatta
    98881 gatactaaaa atttaaatat cacaatgata aactggtgta taatgtaaac aaaagtcgca
    98941 tatttatctc caattccatt cagtattttg atattaatcg ctttaggtga tttaatcgcg
    99001 aaaatcatca atattatggt tgctagcaca gaacttatat agacctcaaa agaattaccc
    99061 aagatataat attctaaaaa tattagtatt ggatagataa ttgttcccaa gattaatatt
    99121 ttgtttatta ttttacaatt aataatcttc ttttgattct gtgcaataag aattcctatt
    99181 ccaaaaaatg gtattcccat aaataaaaaa tttctataaa aaattgaatc gctaattgta
    99241 gcttccataa tgaaagaaaa tagtaaaagc atagaaatcc atcgttttgt caatagtagt
    99301 cttttattgg aaaaataaac tgcatattac cttctctcca aaacatccat acaaatatta
    99361 ttacataaaa aatgtacttc ttaatatcaa tctaaatatt tttttaattc tattctttga
    99421 aatattatat gaataaaagc cagaaatcaa aaagaacatt ggaactgcaa atcgtgctat
    99481 tatttgataa aacgctccaa tttttcctgg tagccatata tgaatagcaa caacactaaa
    99541 acatgctaat acttttattg catgcaaagt actattatat gttaatcctt tatctttagt
    99601 aaccatcttt cctacctatt taacaaaata catttcccaa aatcaaacct gtcactcaaa
    99661 acaataaaaa aatagttcct aacttatttt attattttcc aaatcatcta aatatctgat
    99721 ataatcaaac ctaaactcta gctgtaactt actcaaaatg tcatatcaat cccttataat
    99781 gacccctagc tccatctaag aaatgagtac tcacattatt cgttaactac actgcaccga
    99841 tattcttact ttaataatga agctataata tagcttagtt tatctctata atctcaatta
    99901 ccaaagtttc aaatactttc gtttatttaa tagtatccaa ctaaataaaa taaaactaat
    99961 attttataat gtatttttat gtacaacctt tcgtataatc ttttccttca ataacttaaa
   100021 atgtaaattt cttgacatta aaatatagca acaacaaaaa ataacatata ctattccacc
   100081 caaaactatt agtaaaataa gactcattat attgtatggt aactgagttt tgagtgttat
   100141 aataacaagg tacataatca gaccaaatag gtagaatatc aaaccgtttt tcaaatatct
   100201 ttttaaatct aagtctcttc ttactgacca aaactgcatt ccagacaata caaattctgc
   100261 caaaactgta ctaactgttg ctcccatagc accaaaaggt tttataaaaa aatagtttag
   100321 cactagatta acaacagccc ccgcaattag agacactaca taatctttat ccttagctct
   100381 aggaatcaaa tactgagtcc taatgatatt tcctaataca gagaagacaa aagccggaga
   100441 catagcagaa atcaatctac ctgattcaag aaattcttct ccccaaaata taatggaaaa
   100501 aatatcagat accgatatta gcccaaacat caatacacta gaaataatca tcacgtataa
   100561 aattgttacc tctatgtagt atttactctt ttctttctgt ccttccgcta ataaatagga
   100621 agttcttggt aacataacgg cccctaaagc tgcaatcaaa gctttaggaa tttcaataat
   100681 tctacctgca ttgtcataaa atccaacctg ctttacatca accattaaac caagcatata
   100741 tttatccata ttagtaaaaa tactaatggc tagtacagga ataaaaagaa ttaaaattgg
   100801 cttgatatga ggtagtaatt cctttaattg aatttttttc caagttaata ttccttttaa
   100861 ttgtccccat agtaaaagtt ggccaactaa agttactgat ccgtttataa atgtgtattt
   100921 ccataaatct gtgccttgac gcacacataa aaaaattaaa aataatccta aaagtttgac
   100981 taatgtattc ctaaaaacga tttgcttaaa attttctaat ccatagaaaa accaagtaat
   101041 atcaacagca tttgataaca ataaaaagag ttgtaatatt gcaataactt tgtaatgtac
   101101 tgcccccaaa tatagataag caagataagc tatagttacc agaatagaca ttatcaactg
   101161 gatagagtag atactccaaa acgtttttga tagaatatcc tttccttctc gtttaacagt
   101221 cgcaattgtt ctatttccgt aatttgcaat tccaagaagc ataaacatca taaagtaaag
   101281 tgcaaccgac atagtaaaag aatgaatacc taaattttca gcacctaata tccgtgataa
   101341 ataaggagaa gttatcaagg gagctgcaat cccaattaac tgatacccca tattgtaggc
   101401 taaattttta ctaattttat tactcatttt tctaaacttt cgaagatact atgaacttat
   101461 aaaaagtgtt aacaccgcta gaataatcta tatgatgatt taatttatga aacgccgaaa
   101521 tatgcttcag ttgttcccac cgtttttccg aaaattgttc attcaactca aaatgaagta
   101581 tatgaggaga atgattatta aaagtaggga cagcagacca ttcgattggg taccgctctg
   101641 tagctattgt aaaacatata tggaacaaaa aataattaca taaactattt tttcttcgcc
   101701 agtaggccca taggagtttt ctcgtataga gtaatatagg atgattacta tatgacgaaa
   101761 ttaaccaact tgatgctaca atagcttgtg aatcttttct tgataaattc aaagatttat
   101821 atacaaaaag tggtacctca agatttgaga aatctcctcc tgtattcaac actgttgcat
   101881 ctacccataa tcctccatgg cgacatagaa gatctatcct aaggatatca gagtaatgcg
   101941 cacgagaaat ccatcctttt ttgtattttt caataatata gcctggaatc tctgtataat
   102001 cacttatatt tttttctgtc aacacaatga tttctcttcc ttgaagttga ttcctcattg
   102061 attgaataca tgttttaatt aactctgggg catgctcttc tccctgaaac caacaaatcc
   102121 aaactttatt tgaaaactcc attttatatt taagctcatc tccagtcaac gaaatatgcc
   102181 taaacttctt ctttagtttt ctatatgcta tatcggtatc ttgttgaaaa gctatatttt
   102241 gattttttat aatatataat ggaataattc tatgaatttt atccttcaat ttactataaa
   102301 aagaatgatt tttaatagaa tctaaaattt tttctatcat tatgtttcct atactctaca
   102361 ttacttttga ttttacataa gctgctaaac gaatatctat aaatcctaga atgttctgca
   102421 caattagtct aatatcattg tttcgtgtat atttagcgaa ctttctaaac tgtcgttgta
   102481 aatacttcga aaaattagga tttaaaatct tactatgatt ggtagtcgct gtaacaatcc
   102541 aattgcagta ctgttgacac gctttttcgt gcaaaaaaga atgccccttt tctgaataaa
   102601 actcaatgcg tgaagtatgc atctcatcct tcatctttat tttttctaaa gtcatattac
   102661 tttgtacaat gcttcctttt cgttgaacgt ataaatataa cggctcctct acaattgata
   102721 cccttttaca gtcccaaaat agaggatagt taagaaattc atcctcatac aacattcctt
   102781 ttttaaattt taatttttca aataaagttg accgataaag cttattccaa gcaacaacat
   102841 agcgatagcc gtcggctgtt aatacttttt ctaatatttg ttgaccagtc aagcatattt
   102901 ttcccgaatc taatagctca tcttttattt tttccccttt ttcatcgact aataaaaaag
   102961 aacaaatcga cacctcggaa tcattatttt ttatagaaga atacaacttc cagacataat
   103021 ccttagatat gtagtcatcg ctatcaataa acgctacata ttgacctttc atttgctcaa
   103081 ttccaaaatt ccgagcatct gataaaccac cattttcttt atgaaatact cttatcctag
   103141 gatcaacttt gctaaatgat tcacaaattt tcccactact atctgtgctt ccgtcatcaa
   103201 ccaataaaat ctcgatattt tgataagtct gattcaaaac actttctatt gattttttta
   103261 aatatttttc cacgttatag actggaacaa caatgcttat caaatcttcc ataacttatt
   103321 tatccttcat ttttaatttt tcttctcttc caccactctt taaacgaata aaaagaataa
   103381 atcaacactg gaattttcaa ttttagtaaa taaaaaacaa tcatctcatt tatattttta
   103441 ggcatctttt ctttgctgac tttttcatct aaaaataatc tatacttttt taattgttga
   103501 gcaatttggt ctagtttttc ttttgatgaa tacggagaat caaatttaaa taaattattt
   103561 acatacaagt tagcaaggta aaatctaaaa tccatatgtt gcttatagta gttctcctca
   103621 attttaggat aaacttccaa cagttgattc cataactggt tctgaatcat tagggaattt
   103681 tcaatattct gcacatagcg cttagataac gactgtggat ttacattttg aatattataa
   103741 tacaccccgt caataactcc aatactttta gaaaccatta agtattgata cacaaatgac
   103801 atatcttcac ctagtgacat ctcagtcgaa aaagtaatat tattttcttc aattattttg
   103861 cgaaaaaaca atttggcaca agcacttctc ggaaagatat caacaaaatg agcacctatt
   103921 tcttctcttg tacgtgcaat aaatgaagtt gacttattct catttccacc gtattgagtt
   103981 gtagcaggtt ctttatgcca acaagataag agatcaactt tattattttt tacaaattgg
   104041 tacattttag aaagcatacc atcatctaaa atatcatctg aatctaaaaa gaatacgtat
   104101 tctccgcttg catgagataa acctaaattt ctggcagcag atactcccat gttcacttga
   104161 tgaaatatct tcacttgggg attatcacta tactgttcaa gaattcttga tgtagaatcg
   104221 ttcgatccat cgtttactaa aattacttca aaagattcta aatcttgttt taaagcactt
   104281 tcaatacaat tattaatcgt gttttcagca ttgtatactg gaatcaccac tgatatttga
   104341 atttccatct caatcccttc ttattaattt agtagactta tacgctgcat tacctattgc
   104401 tagaaagaaa aatacaagat aagttgatct agtgaacgta ctattccaaa caataatgct
   104461 aatcatcacc acaaaagcta tgatggatac aattagtctt tcactttgct tattttttcc
   104521 tctagtaata gttccccgta tgaataatga caacaaaaat gaataaagca aaatcactga
   104581 aataaaacca ccatctgcaa gcattttacc aagttcataa atataattaa cagagtatga
   104641 acctagtcct ttcccaaata tagcactaat ataatcatga taaaataagt tgtcccatag
   104701 gaaggaaata gtatttgttc gtcccgcaaa ctctgtccta ttctcatatg ataatgcctt
   104761 tgtaacatta aaaaaagtat acaaattatc aggtaaaact atctcaatga gtttataggc
   104821 aattaaaaaa agaagagata ttccagcagc tgtactaatt attcgtattt tttttactgt
   104881 ttctgacttt tgaaatataa aaattagaat aatagaaaat ataaaaatga caaaaaaaat
   104941 ctttatttct gctaatgcac aaattataca cgaaatagca atcaatatta atgacttcat
   105001 tgttccccat ttaccataca gataatatac agtagataaa acacttaagg ctaagcaata
   105061 aaatccttgg attccatttg cataattagt aaaaccaaaa atcccattag tgaagtcagg
   105121 gtgcaaatgt aatactatat tttgatgtaa aactaataat aggttcaata tctgcataaa
   105181 ataagcaatg tttatcaatg atgaaaaggt tctatcatct agatagctat ttgtcataaa
   105241 ataaactaga aatgctccca gtatatatct tcctctcata acaaatccat atatattaag
   105301 agtaccccaa gtaaaactaa ttaatagaaa tatcagcaat ataaaaaaga gcattaaact
   105361 aatgtgagga tttttaactc ttattttccc tgcagaataa gaatctacaa aaacaattac
   105421 tgctgctgcc aacaataata agtcaggtat cgtaaataat agagatacag aataatatga
   105481 gtatagcaat tcactaaata acgaatatat gaataacaac ttgatacagc tatttatgta
   105541 cttagtcata cttgatgtca cctgtctcca tcaactgatt aatcatatct ataaatttct
   105601 ccataaatag attatttttg ctcttcaaat ctgatttttt tcgctcatca aaattagaaa
   105661 tataggaatt aagatcactt atgttagtga tgactgtcaa attatagaca tttaacactt
   105721 tctcaacaaa ttcaagttga tggtcgttca catgctcacc aaattttttt aatctcggaa
   105781 caattatcgg acttttccct ttagcaataa ctgccataaa cgtagctgga ccgccatggg
   105841 taatgattgt atcagcttcc tcaataaatt gattcatttt ttcataagat attaattttt
   105901 cccatttaca aaattttgga acataattag agtatcctgt ttgaataaaa acatcatcct
   105961 gaataaatcc ctcacctttt aatctatcaa cctctttaat aagtcgatta aactgttgtt
   106021 catgagtacc tactgtcaca aaaatcatta gaaaatccct ccgagattaa ttgcctttgg
   106081 gtatactttt ttcatttctt cccattgaac aataaaccta tccgttactg gataaacaag
   106141 ttttcctgtc agtgttgaag catcaattct atcaaaaact tctatataca ctgtctttga
   106201 tccaaataac ttcccaatat aaaagaaagg aacagcgata gcggcaccag aagaaataat
   106261 caaatctggt ctctcttttt ttaaaatttt ataggcgaga aaagtatttt ttattaaatt
   106321 ttttatatta cgattggttg gataataaca gggatataca acttcctcag agagtacact
   106381 ccgagcgtcc gccttatcaa aagtaaccca aaatctttct ttatctttcc agaaaggttt
   106441 taaaagatat aaatgagtca gatgacctcc actagatcca actaaacata ttttcatttc
   106501 ctacttcgct ccgtctctca taaatacaac tttaactgtc ttcaataaaa tttcaatgtc
   106561 tttccaaatt gtccaatcgt ctatataggc tacatctaat ttgacaactt catcaaaatt
   106621 cttaatctca cttcgtccac tgacctgcca taagcctgtt ataccaggtt taaaacttag
   106681 ccgacgtttt tgttctgggg tatagtgttc atactcgtcc actgttggtg gccgtgtgcc
   106741 aaccaaactc atatctccct ttagaacatt ataaaactgt ggtagctcgt ccaagctagt
   106801 cttccgtata aaacgaccaa ttttcgtgat acgaggatca tcgtccacct taaacattcc
   106861 accctgcatg gtattttgtt ccatgagttc tctttttttc gcctcggcat ctacacacat
   106921 agagcgaaac ttataaaaag tgaactgacg accatttttt cctatacgcg tctgagcaaa
   106981 aatagtagag cccccatcct ttcgaatcaa aggaaccagt acaatactgg ctagaccaca
   107041 tagtatcagc cctaccaatg cacccacgat atcaataatc cgcttagcaa ttacatgact
   107101 agtcttataa aatgttgtag aaaaagtcac aacgtttaat cctgccatct cacggatttg
   107161 cttgttacgt gccaaactac gatcaaaagc atttagattg actgttacat caattcccat
   107221 cgtttcaaac tgagagacaa gctctccaat attgtatttt tcacttggaa gattgataaa
   107281 gacttcatcg accacctcat gagtcgcaaa gtttactatc tccccctctg ctactacctt
   107341 taaacaatca tgctgaaaat ctggtttatc taagacactg acggctacca acttcccaac
   107401 aacctcattt gattctatta atctatccag taccttttcg acacgagaag ttgctgtaag
   107461 taggagaatc ttcttacttc ctttaaagtt gggataagcc cgcttccaat accacttgat
   107521 aaataggttt agcacataga ctaagagagc atgtaatgtg aggaagtaaa tcatgcctcg
   107581 tctggaaata ctaaatcgat cctctaagaa aaaattagaa atactaatcg ctagtgcaaa
   107641 gaataggata tatttcaatg tctggacaag ttcaatcaaa tatccccttt taaagaaatc
   107701 ctgtccataa tcactgatat aaaagacaaa ataatggagg atataaagtg caatagctgt
   107761 tgttgaaaca atctccgctt ctctcacagc actaagtaga taagtcaata aaataacaag
   107821 aaaactctgg attatggcca atgaagactt tactattttt ccattcatct ctatcccccg
   107881 acctattttt tatttttccc gtaatctcca taatttccat aagaaccgta tttgtctact
   107941 gaagtatcga atttattcaa cacaactccc aaaaacggct tccctgtgtg ttccaactgt
   108001 tcttttgctt tttgaatatc ccgtcgattt atttcacctg cctccgtcac taaaatagaa
   108061 gcatcgcatt ttcgcgtaat aatagccgca tcaatcacga caccgacagg agcagtatct
   108121 acaatgatgt agtcaaaata tttacgcaat gtttcaagca ttgtactgaa attcttactt
   108181 tgaagaagag ctgtcggatt cggtgacaca gagccagcct gaattacaaa gagattttcg
   108241 atattggtat cacaaagccc ttgtgatagg tctgtagttc ctgataaaaa ttctgtcagg
   108301 cctgtaatct tatcccttgc tttaaagaca cctaacataa cagaattgcg aatatctcca
   108361 tcaatcagca gcgttttgta acctgcacgc gcaaaagccc aagcgatatt ggtggaagtc
   108421 gttgattttc cttctcctag tttcacagaa gtgatagaaa atactttcaa accatctcca
   108481 cttaactgta ggttcgtgca caaagcgtta taatattcct ctgccttttt tacaaaatcc
   108541 aattttgcct gtgagatttc taacgttggc ataacttcct cctatttcat tttgtccaaa
   108601 tctggaacga gccctaaaag tggaatttgc agtacatctt caacatcttc aggacgtttc
   108661 acacgggtgt cgagcaactc aatcaaaaga acagcaatta ctgttacgac ggctcctcca
   108721 agaaaaccaa acaaggtgtt gcgtcgaaca tttggagaag agggagtcgt agctggtcgc
   108781 gcttcttcaa gtgtcgttac atcagatact cgcgttacag cgacgatctt ttctgcagca
   108841 acttctcgta gagaattagc gatacgactg gcttcctctg gctgtttatc cttgacagag
   108901 attgagacaa tacgggtatc aactggtact gtcactttaa ttttattagc caaacctttt
   108961 ggcgtcaaat ctagtttcaa atcagaaaca acttcctcca aaacatcctg cgataggata
   109021 atttcacgat agtctttaac caagtatgtt cctgcctgca agtcttgatt ggttaaacca
   109081 gacttctctc cctgatcacg gttaactaca taaatccgag tcgtactagt aaactcaggt
   109141 ttgataacaa aagtactgta ggcaaaagca actgaagaag ttataattgc cactaataaa
   109201 atgaccaact ttcttttcca caaagatctg aatagttgca atacatcgat ttccaaagtg
   109261 ttttgttcct ccatattttc tcctaaatta attgatccat tataattttt ctgggattat
   109321 ctacaaaaag ttcctgagcc ttcgcttctc cgtatttttg ggtaacaagg tcatatgctt
   109381 ctgccatatg aggaggtctg ccgtctagat tgtgcatatc acttgcaatg acatggacca
   109441 aatcctgctc taaaaaatac tgagctcttt ttttcatgaa tttataacgt tcgccaaaaa
   109501 gtttggattt gaggacatgt gaactattta cttgcgtgta acagcccata tcgatcaatt
   109561 ctcgaacgcg tttttcatta ttttcaagag catcatagcg ctcaatgtgg gcaatgactg
   109621 gagtaattcc caacatcaag atcttgctca aggcgctatg aatatcgcga taaggagtgt
   109681 tcatactaaa ctctatcaag gcataacgac tatcattgag ggtcggaatc cgcttttttt
   109741 ctagcttatc cagaacatct ggtgtgtagt aaatttcagc cccgtaagca atgaccaagt
   109801 cactcgccac ttccttagct atttcccgaa cctgaagaaa gttttctgct atcttctctt
   109861 ccggagtttc aaacatgccc ttgcgacggt gagaggtaga gacaatggtt cgcaccccct
   109921 gcctgtagga ttctgccaag agagccttgc tttcctctct tgacttggga ccgtcatcta
   109981 catcaaaaac gatatgcgaa tggacgtcta tcatttcatc taccctccat cacatcctct
   110041 atagctgctt taactacagc taaactacta tcatctattt ccatcacata gaggttactg
   110101 tctggtattg cataagaagg aagatccatc cgacctgtcc cttttaaatc ttgagaattt
   110161 actttataat tccccccact ttccaactga gtattcacta aatctatcat agtctcaatc
   110221 ggcatatttg tttgaagaga atcctgcaat ccttgaagaa tactactata gtttttcaaa
   110281 acctctgtag aagttaactt ctgaataatt gctacaatga ccttttgttg gttgcgacca
   110341 cggtcacggt ctccatcggc tagtgagtag cgttcacgta caaaacctag agcctgctca
   110401 gagtctagat ggacattccc tactgggaaa tggaacttcc catgtagagc tgaaaactct
   110461 tgatcattat gaacatctac ccctcccaat aagtcaatca ttttcaagaa agaagtgaag
   110521 ttcaatcgca catagtaatt gatatccact ccatagagat tttctaaggt gtgaatggac
   110581 gaatcaactc cataaatgcc cgcatgggtt aatttatctt tttgattatt tccaccatct
   110641 gcgattggta cataggcatc acgtggcgtt gtggtcaaga ggattttctt ggtatctcga
   110701 ttgacagtca tcaggatatt gacatctgat cgcgacaccg aactaatagg accataggtg
   110761 tcaattccac taacatagat attgaaagac tgattcttag acgtcttagg agcttctact
   110821 tttttagtga atcccttggt ataaatcttt tttatcttcg atgcgtagtc tggatactct
   110881 gactcgatga tattttcaaa gacactattt aagacaatgg ccttagtctc ccctgcaatc
   110941 aaactcttgt aagctgccaa gtaagacgaa ctctggtcga ccgtcaaatc ggtattctga
   111001 cttgacttaa tatcagctag tagtttttga atattttcgt tatcagtccc agtcggtgct
   111061 gtcacactcg tcaattgcgt aacattttcg atatcactat ctgctaaaac agcgacactg
   111121 attgaatatt ctgagtaatt agaagtcgca tttaaacgat tggtcagtcc aacaaactgc
   111181 tgtactgcaa agagcgacac agagctgaca aggatagaga acaccaacag aaaaatagta
   111241 aacttttcag cttttttata gataatcaag agtagcccta ccaaggcaac tagtaggact
   111301 aacgcagtta ccactaggtt aagatatcta aaagcaagga tattgtactt aaagattaag
   111361 aacaataaaa aacaaactaa caataaataa atagtcagca aaacgatatt aacacttcgc
   111421 ttcactttct gtgaacgtga ttttttaaaa cgtctactca tgattaacac ctataccttg
   111481 aacatcatac gattatatca cttttttacg gtaatgtcta cattttttta ctatctgcat
   111541 ctttaagtat cttagtagac ttcccgcgaa acaaaaatat agtaaaatga aataagaaca
   111601 tgacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag cagaggtgta
   111661 ctattctagt ttcaatctaa ttatgaacaa gacccagaaa aagtagcctt atttcttaag
   111721 aattttaata gtttaaagca cctagcacct gtttagattg acgaaacagg attcgatact
   111781 tatttttatc gagaatatgg tcgctcatta aaaggtcagt taataagagg taaagtatct
   111841 ggaagaagat atcagaggat ttctttggtt gcaggtctaa caaatggtga gttaatcgct
   111901 ccaatgactt acgaagagac gatgacgagc gacttttttg aagcttggtt tcagaagttt
   111961 ctcttaccaa cattaaccac accatcggtt attattatgg ataatgcaag attccataga
   112021 atgggtaagt tagaactctt gtgtgaagag tttgggtata aacttttacc tcttcctccc
   112081 tactcacctg agtacaatcc tattgagaaa acatgggctc atatcaaaaa gcctcgtaaa
   112141 aggtattacc aagttgccat accttttatg aggctctttt gtcttgttct tgtttcaatt
   112201 gactatgtta tcagcgtaat agtctaatag atagttaaat gtagttggat ttccaccaaa
   112261 ggttgatgag taagtttttg tatctgaacc tgattggccg caagcagcta aaagcaaagc
   112321 agatgcaaaa gtcatgcctg cactaaggac tcgcttcttt atgttcatct tctttctcct
   112381 taaatagtgg gaatttgtaa agttaattga atttcgagaa tgaaagttta taaaccttgg
   112441 ttataaaaaa caaaggattt ctgtctttta tacagtcctc ccttgttttt atatgatttc
   112501 aattttaaat ttttctgcaa aaaatattta tagtaattcc acacagaaag catcccatgg
   112561 agccaagacc tgtttttcaa gtacttcttt agccgcagtg ttttcaatca agacagattt
   112621 gacttttcct tctactgtca agtcttgctc ttcattggac aagttagcca caactaggaa
   112681 gcgacggtcg ccatccttac gtatataagc aaagacctta tcagccgtat caagcaattc
   112741 aaagtcagct cgaactagcc agctattctc cttgcgaatt tggaccagtt tctgataggt
   112801 atagaaaata gaatctggat ttgccagcgc ttcttggaca ttgatcatct cgtaatttgg
   112861 attaaccgcc aaccaaggtt gacctgttga gaaaccagcg tttttgctct cgtcccattg
   112921 cataggggta cgggcattgt cacgtccaat aacacggata ctgtccatga tttcttcaat
   112981 cggaacacct ttttcaagag cctcacgcgc atagttgaga gattcaatat cttctacttg
   113041 atccagtgtt tcaaacggat agttggtcat cccaatctcc tcaccttggt agatataagg
   113101 agttcctctc atgagatgaa gtaagattgc aaaggctttg gcagattttt cgcggtattc
   113161 ttggtcattt ccccagattg agacaatacg agggaggtca tggttgttcc agaagaggga
   113221 attccagccg tcctcaactc ctaactctgt ctgccatttg ttgaagattt cttttaactt
   113281 agcgatattc agctcttttt gatagtgcca tttaggttga ccttcctgat actgaagacc
   113341 gatatgttca aactggaaga ccatagacaa ttcttgcccc tttggatcag agtagagctt
   113401 ggcaatctct ggcgttgctc cccaagtctc ccctactgtc aagagatcct tatctccaaa
   113461 ggtcgcctga ttcatttcct tgagataggg atggagcata ggaccattat tgactacctt
   113521 ctcgtcagga attttgccaa tcatgtcaat aacatccata cggaaaccac caataccttt
   113581 atcaatccag aagttcatca tctcataaat tttctggcga agtttttcat tttcccagtt
   113641 gagatccggc tgtttcttgc tgaaaaagtg gagatagtat tgacctgact tttcatcgta
   113701 ttcccaagca gacccactaa agatagaatc taggtcattg ggttcatcgc gccagatata
   113761 gtagtctcgc tcagggctat taggattttc acaggcctct acaaaccagg catgctcatc
   113821 cgaggtatga ttgaccacca agtccatgat gatacggata tcacgcttct tagcttctgc
   113881 aatcagttga tccatatcct ccatggttcc aaaaatcgtt gcaatcgctt gataatcagc
   113941 aatatcgtag ccattatcat ccatagggct gtcataaacg ggagaaagcc aaattgctgt
   114001 gattcctagc ttggctagat agtccaactt actggtaatt cctggcaaat cgccaattcc
   114061 atctccatta ctatccataa aactctttgg atagacttga tagactacgg cattatgcca
   114121 ccatttttct tgcatctgtt tacctcatta ttttcataat ctatagtcta tgatagcact
   114181 ttttaaaatt ttgtgcaagc gtttgcttaa tctttttaat ttctttttta gctccgtagt
   114241 ttcctaactt ccaatttttt attataatag agtccagagg taaaaaaatg aaaaaacaag
   114301 cttttagttc tgaacaatat ttaaatctac aacgcgacca catcttagag cgcattaacc
   114361 aatttgacgg caagctctac ttagagtttg gcggtaaaat gttagaagat ttccacgctg
   114421 ctcgtgtcct tcctggttat gaacctgaca acaaaatcaa gctcttgcaa gaattgaaag
   114481 agcaggttga ggttgtgatt gccattaatg ctagcaacat tgaacattcc aaagcacgtg
   114541 gcgacttagg catttcttat gaccaagaag ttcttcgttt gattgacaaa ttcaatgaat
   114601 tagggatttt tgttggttcc gttgtcatta cacaatacgc tggccaaccc gctgcagatg
   114661 ccttccgcaa ccaacttgag aaaaacggaa ttgattctta tcttcattat ccaatcaaag
   114721 gatatccgac ggatatggat cacatcattt ccccagaagg catgggcaaa aacgactaca
   114781 tcaaaaccag tcgcaacttg attgtcgtaa ccgctcctgg acccggttct ggaaaattgg
   114841 caacgtgtat gtccaatatg taccacgacc aaatcaatgg catcaagtct ggctacgcta
   114901 aatttgaaac cttccctgtt tggaatcttc cccttcatca tccagttaac ttggcttatg
   114961 aagctgccac agctgacctt gatgatgtca acatgattga ccccttccat cttcaaacct
   115021 atggagaaac cactgtcaac tacaaccgtg atatcgaaat cttcccagtg ctcaagcgca
   115081 tgttggaacg tattctcgga aaatcgccat acgcttcacc gacagatatg ggtgtcaaca
   115141 tggttggttt cgctattaca gatgacgagg ctgctgtcga agcttctaaa caagaaatca
   115201 tccgtcgtta ctatcaaaca gttcttgact tcaaagctga aaaagttggc gaagctgccg
   115261 tcaagaaaat tgagttgctc atgaacgacc tcggtatcac acctgcagac cgtaaggttg
   115321 ctgtcgttgc gcgccaaaaa gcagaagaaa ctggcggacc agccctagct cttgaattac
   115381 caaatggtga cattgtcact ggtaaaaact cagaactctt tggccctaca gccgctgcct
   115441 tgatcaacgc catcaaaaaa tcagctgaca tcgctaaaga agtaaaacta atcgagcctg
   115501 aagttgttaa gccaatccaa ggacttaaaa tcgatcatct cggtagccgc aatccacgcc
   115561 ttcattcaaa tgaaatcctg attgcacttg ctatcacagc tacagaaaat cctgatgctg
   115621 cccgcgctat ggaagaactc ggcaacctca aaggaagcga agcccactca accatcatct
   115681 tgactgatga agacaagaat gtccttcgta aactgggtat caacgtaacc tttgacccat
   115741 actaccaata cgaccgctta tatcgtaagt aaagatttca acctctccag cctcggagag
   115801 gttttctctc tgtctcagga gcaagcttta tgatataatg agagaagaaa actgaaagga
   115861 tttaccatgt caaaagaagt tattgtcgaa agttttgaac ttgaccacac cattgtcaaa
   115921 gcaccctatg ttcgcttgat tggggaagaa acaggaccaa aaggagacat catctccaat
   115981 tatgatattc gcttggtgca accaaacgaa gactctatcc ctactgccgg ccttcacact
   116041 atcgagcacc tcttagccaa actcatccgt acccgcattg acggcatgat tgactgttcg
   116101 ccatttggtt gccgcacagg cttccacatg attatgtggg gacgtcacac cagtgctaaa
   116161 atcgcagctg ttatcaagga ttcgctcaag gaaatcgctg aaactactac ttgggaagat
   116221 gtcccaggga caaccatcga atcttgcgga aactacaagg accacagcct cttctctgct
   116281 aaagaatggg caaaactcat cttggaacaa gggatttcag atgatgcctt tgaacgtcat
   116341 gtgatttaaa atcgagtagg ggataatctc tagcccctct cacaccaccg cacgtgccgt
   116401 tcggcatacg gcggttcaac taacttttaa cgcatgccgt tcaaggtaat aatccaaaca
   116461 cgaaaccagt ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt
   116521 ctgagctact aattgataat ggtcgcccca gccagatacc ttatctgcta tccatttagg
   116581 aac
//
LOCUS       DBEROT010000002        92159 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.02, whole genome shotgun sequence.
ACCESSION   DBEROT010000002 DBEROT010000000
VERSION     DBEROT010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 92159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.02"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..402)
                     /locus_tag="ACL8CG_000113"
     CDS             complement(<1..402)
                     /locus_tag="ACL8CG_000113"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1342789.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQM"
     gene            472..1131
                     /locus_tag="ACL8CG_000114"
     CDS             472..1131
                     /locus_tag="ACL8CG_000114"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGS1342790.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEKSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(1183..2334)
                     /locus_tag="ACL8CG_000115"
     CDS             complement(1183..2334)
                     /locus_tag="ACL8CG_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1342791.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(2349..3080)
                     /locus_tag="ACL8CG_000116"
     CDS             complement(2349..3080)
                     /locus_tag="ACL8CG_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342792.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDENSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            3309..3410
                     /locus_tag="ACL8CG_000117"
                     /pseudo
     CDS             3309..3410
                     /locus_tag="ACL8CG_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(3382..4158)
                     /gene="trpA"
                     /locus_tag="ACL8CG_000118"
     CDS             complement(3382..4158)
                     /gene="trpA"
                     /locus_tag="ACL8CG_000118"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGS1342793.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(4151..5374)
                     /gene="trpB"
                     /locus_tag="ACL8CG_000119"
     CDS             complement(4151..5374)
                     /gene="trpB"
                     /locus_tag="ACL8CG_000119"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGS1342794.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGSPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(5352..5951)
                     /locus_tag="ACL8CG_000120"
     CDS             complement(5352..5951)
                     /locus_tag="ACL8CG_000120"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGS1342795.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEVAE
                     LAKLIPADVKKVGVFVSPSRAELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            complement(5938..6705)
                     /gene="trpC"
                     /locus_tag="ACL8CG_000121"
     CDS             complement(5938..6705)
                     /gene="trpC"
                     /locus_tag="ACL8CG_000121"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGS1342796.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(6702..7706)
                     /gene="trpD"
                     /locus_tag="ACL8CG_000122"
     CDS             complement(6702..7706)
                     /gene="trpD"
                     /locus_tag="ACL8CG_000122"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGS1342797.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(7717..8283)
                     /locus_tag="ACL8CG_000123"
     CDS             complement(7717..8283)
                     /locus_tag="ACL8CG_000123"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGS1342798.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(8280..9641)
                     /gene="trpE"
                     /locus_tag="ACL8CG_000124"
     CDS             complement(8280..9641)
                     /gene="trpE"
                     /locus_tag="ACL8CG_000124"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGS1342799.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFYILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(10013..10264)
                     /locus_tag="ACL8CG_000125"
     CDS             complement(10013..10264)
                     /locus_tag="ACL8CG_000125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342800.1"
                     /translation="MKIKEQTRKLAVGCSKHSFEVVDKTDEVSSKHCFEVADRTDEVS
                     SKHCFEVADRTDEVSNHTYDKATLTRFEEIFEEYKGVPR"
     gene            complement(10359..12107)
                     /locus_tag="ACL8CG_000126"
     CDS             complement(10359..12107)
                     /locus_tag="ACL8CG_000126"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1342801.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPIFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTHLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(12109..13833)
                     /locus_tag="ACL8CG_000127"
     CDS             complement(12109..13833)
                     /locus_tag="ACL8CG_000127"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1342802.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNRSYISAKRIKEVFVEAPEDIHSELEQKQVTSDRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIASVPQKVELFKGTIRSNLTLGFNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(13893..14831)
                     /gene="msrB"
                     /locus_tag="ACL8CG_000128"
     CDS             complement(13893..14831)
                     /gene="msrB"
                     /locus_tag="ACL8CG_000128"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS1342803.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(14898..15050)
                     /locus_tag="ACL8CG_000129"
     CDS             complement(14898..15050)
                     /locus_tag="ACL8CG_000129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342804.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEVSSRHCFEVADRTDEVS
                     NIYTVR"
     gene            complement(15126..15995)
                     /gene="thrB"
                     /locus_tag="ACL8CG_000130"
     CDS             complement(15126..15995)
                     /gene="thrB"
                     /locus_tag="ACL8CG_000130"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGS1342805.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(15997..17283)
                     /locus_tag="ACL8CG_000131"
     CDS             complement(15997..17283)
                     /locus_tag="ACL8CG_000131"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGS1342806.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(17434..18171)
                     /gene="mecA"
                     /locus_tag="ACL8CG_000132"
     CDS             complement(17434..18171)
                     /gene="mecA"
                     /locus_tag="ACL8CG_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGS1342807.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(18371..19405)
                     /locus_tag="ACL8CG_000133"
     CDS             complement(18371..19405)
                     /locus_tag="ACL8CG_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS1342808.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(19434..20867)
                     /locus_tag="ACL8CG_000134"
     CDS             complement(19434..20867)
                     /locus_tag="ACL8CG_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGS1342809.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGILFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(20883..21869)
                     /locus_tag="ACL8CG_000135"
     CDS             complement(20883..21869)
                     /locus_tag="ACL8CG_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1342810.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNSIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(21871..22974)
                     /locus_tag="ACL8CG_000136"
     CDS             complement(21871..22974)
                     /locus_tag="ACL8CG_000136"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1342811.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLYQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(22964..23809)
                     /locus_tag="ACL8CG_000137"
     CDS             complement(22964..23809)
                     /locus_tag="ACL8CG_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1342812.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSCILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(24088..25362)
                     /gene="psr"
                     /locus_tag="ACL8CG_000138"
     CDS             complement(24088..25362)
                     /gene="psr"
                     /locus_tag="ACL8CG_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGS1342813.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(25359..26207)
                     /gene="pheA"
                     /locus_tag="ACL8CG_000139"
     CDS             complement(25359..26207)
                     /gene="pheA"
                     /locus_tag="ACL8CG_000139"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS1342814.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(26204..26680)
                     /locus_tag="ACL8CG_000140"
     CDS             complement(26204..26680)
                     /locus_tag="ACL8CG_000140"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGS1342815.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(26673..27956)
                     /gene="aroA"
                     /locus_tag="ACL8CG_000141"
     CDS             complement(26673..27956)
                     /gene="aroA"
                     /locus_tag="ACL8CG_000141"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGS1342816.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQDVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVAGGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(28048..28386)
                     /locus_tag="ACL8CG_000142"
     CDS             complement(28048..28386)
                     /locus_tag="ACL8CG_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGS1342817.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(28397..29500)
                     /locus_tag="ACL8CG_000143"
     CDS             complement(28397..29500)
                     /locus_tag="ACL8CG_000143"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGS1342818.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(29510..30676)
                     /gene="aroC"
                     /locus_tag="ACL8CG_000144"
     CDS             complement(29510..30676)
                     /gene="aroC"
                     /locus_tag="ACL8CG_000144"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGS1342819.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(30686..31753)
                     /gene="aroB"
                     /locus_tag="ACL8CG_000145"
     CDS             complement(30686..31753)
                     /gene="aroB"
                     /locus_tag="ACL8CG_000145"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGS1342820.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(31772..32626)
                     /locus_tag="ACL8CG_000146"
     CDS             complement(31772..32626)
                     /locus_tag="ACL8CG_000146"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGS1342821.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(32616..33293)
                     /gene="aroD"
                     /locus_tag="ACL8CG_000147"
     CDS             complement(32616..33293)
                     /gene="aroD"
                     /locus_tag="ACL8CG_000147"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGS1342822.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(33290..34453)
                     /locus_tag="ACL8CG_000148"
     CDS             complement(33290..34453)
                     /locus_tag="ACL8CG_000148"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGS1342823.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVTFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLTMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(35138..36772)
                     /locus_tag="ACL8CG_000149"
     CDS             complement(35138..36772)
                     /locus_tag="ACL8CG_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342824.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFVVAILLVIAFSTSLTAFYNVFYESK
                     DLASYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTTAFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPILTLLGLSLYLGLPIISMIYLIMAWILASVIL
                     SCHHYFKDVKNLSINWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(36753..37502)
                     /locus_tag="ACL8CG_000150"
     CDS             complement(36753..37502)
                     /locus_tag="ACL8CG_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1342825.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQDLSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSSSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDLDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRRDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            37681..39135
                     /locus_tag="ACL8CG_000151"
     CDS             37681..39135
                     /locus_tag="ACL8CG_000151"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGS1342826.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPIADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(39225..41843)
                     /gene="alaS"
                     /locus_tag="ACL8CG_000152"
     CDS             complement(39225..41843)
                     /gene="alaS"
                     /locus_tag="ACL8CG_000152"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGS1342827.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDSSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(41865..42350)
                     /locus_tag="ACL8CG_000153"
     CDS             complement(41865..42350)
                     /locus_tag="ACL8CG_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGS1342828.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(42625..42864)
                     /locus_tag="ACL8CG_000154"
     CDS             complement(42625..42864)
                     /locus_tag="ACL8CG_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342829.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(43109..44179)
                     /locus_tag="ACL8CG_000155"
     CDS             complement(43109..44179)
                     /locus_tag="ACL8CG_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1342830.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENAFQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(44176..44949)
                     /locus_tag="ACL8CG_000156"
     CDS             complement(44176..44949)
                     /locus_tag="ACL8CG_000156"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1342831.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(44946..45752)
                     /locus_tag="ACL8CG_000157"
     CDS             complement(44946..45752)
                     /locus_tag="ACL8CG_000157"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1342832.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WLNLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(45733..46890)
                     /locus_tag="ACL8CG_000158"
     CDS             complement(45733..46890)
                     /locus_tag="ACL8CG_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1342833.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(47050..47955)
                     /gene="murB"
                     /locus_tag="ACL8CG_000159"
     CDS             complement(47050..47955)
                     /gene="murB"
                     /locus_tag="ACL8CG_000159"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGS1342834.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(48067..48819)
                     /locus_tag="ACL8CG_000160"
     CDS             complement(48067..48819)
                     /locus_tag="ACL8CG_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HGS1342835.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(48829..49560)
                     /gene="budA"
                     /locus_tag="ACL8CG_000161"
     CDS             complement(48829..49560)
                     /gene="budA"
                     /locus_tag="ACL8CG_000161"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGS1342836.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            49702..50973
                     /locus_tag="ACL8CG_000162"
     CDS             49702..50973
                     /locus_tag="ACL8CG_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGS1342837.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(50993..51808)
                     /locus_tag="ACL8CG_000163"
     CDS             complement(50993..51808)
                     /locus_tag="ACL8CG_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1342838.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(51965..52618)
                     /gene="phoU"
                     /locus_tag="ACL8CG_000164"
     CDS             complement(51965..52618)
                     /gene="phoU"
                     /locus_tag="ACL8CG_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS1342839.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(52630..53388)
                     /gene="pstB"
                     /locus_tag="ACL8CG_000165"
     CDS             complement(52630..53388)
                     /gene="pstB"
                     /locus_tag="ACL8CG_000165"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1342840.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(53401..54204)
                     /gene="pstB"
                     /locus_tag="ACL8CG_000166"
     CDS             complement(53401..54204)
                     /gene="pstB"
                     /locus_tag="ACL8CG_000166"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1342841.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(54215..55099)
                     /gene="pstA"
                     /locus_tag="ACL8CG_000167"
     CDS             complement(54215..55099)
                     /gene="pstA"
                     /locus_tag="ACL8CG_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS1342842.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(55089..56006)
                     /gene="pstC"
                     /locus_tag="ACL8CG_000168"
     CDS             complement(55089..56006)
                     /gene="pstC"
                     /locus_tag="ACL8CG_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS1342843.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(56006..56884)
                     /gene="pstS"
                     /locus_tag="ACL8CG_000169"
     CDS             complement(56006..56884)
                     /gene="pstS"
                     /locus_tag="ACL8CG_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGS1342844.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(57458..58762)
                     /locus_tag="ACL8CG_000170"
     CDS             complement(57458..58762)
                     /locus_tag="ACL8CG_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGS1342845.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(58763..59536)
                     /locus_tag="ACL8CG_000171"
     CDS             complement(58763..59536)
                     /locus_tag="ACL8CG_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGS1342846.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(59526..59804)
                     /locus_tag="ACL8CG_000172"
     CDS             complement(59526..59804)
                     /locus_tag="ACL8CG_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGS1342847.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(59804..60205)
                     /locus_tag="ACL8CG_000173"
     CDS             complement(59804..60205)
                     /locus_tag="ACL8CG_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGS1342848.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(60415..61032)
                     /locus_tag="ACL8CG_000174"
     CDS             complement(60415..61032)
                     /locus_tag="ACL8CG_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGS1342849.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(61022..61795)
                     /locus_tag="ACL8CG_000175"
     CDS             complement(61022..61795)
                     /locus_tag="ACL8CG_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGS1342850.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(61806..62543)
                     /locus_tag="ACL8CG_000176"
     CDS             complement(61806..62543)
                     /locus_tag="ACL8CG_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGS1342851.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWKEIKKA"
     gene            complement(62548..63678)
                     /gene="hemW"
                     /locus_tag="ACL8CG_000177"
     CDS             complement(62548..63678)
                     /gene="hemW"
                     /locus_tag="ACL8CG_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGS1342852.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(63762..64151)
                     /locus_tag="ACL8CG_000178"
     CDS             complement(63762..64151)
                     /locus_tag="ACL8CG_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGS1342853.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYALQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(64124..64550)
                     /locus_tag="ACL8CG_000179"
                     /pseudo
     CDS             complement(64124..64550)
                     /locus_tag="ACL8CG_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(64551..65339)
                     /gene="lgt"
                     /locus_tag="ACL8CG_000180"
     CDS             complement(64551..65339)
                     /gene="lgt"
                     /locus_tag="ACL8CG_000180"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGS1342854.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(65332..66267)
                     /gene="hprK"
                     /locus_tag="ACL8CG_000181"
     CDS             complement(65332..66267)
                     /gene="hprK"
                     /locus_tag="ACL8CG_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGS1342855.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPKLLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(66397..66573)
                     /gene="rpsU"
                     /locus_tag="ACL8CG_000182"
     CDS             complement(66397..66573)
                     /gene="rpsU"
                     /locus_tag="ACL8CG_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGS1342856.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(66710..67417)
                     /locus_tag="ACL8CG_000183"
     CDS             complement(66710..67417)
                     /locus_tag="ACL8CG_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGS1342857.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            67568..68596
                     /gene="queA"
                     /locus_tag="ACL8CG_000184"
     CDS             67568..68596
                     /gene="queA"
                     /locus_tag="ACL8CG_000184"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGS1342858.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(69257..70290)
                     /locus_tag="ACL8CG_000185"
                     /pseudo
     CDS             complement(69257..70290)
                     /locus_tag="ACL8CG_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(71123..71674)
                     /locus_tag="ACL8CG_000186"
     CDS             complement(71123..71674)
                     /locus_tag="ACL8CG_000186"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1342859.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(72024..72848)
                     /gene="nadE"
                     /locus_tag="ACL8CG_000187"
     CDS             complement(72024..72848)
                     /gene="nadE"
                     /locus_tag="ACL8CG_000187"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGS1342860.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADTMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQELGADPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(72845..74305)
                     /locus_tag="ACL8CG_000188"
     CDS             complement(72845..74305)
                     /locus_tag="ACL8CG_000188"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGS1342861.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(74421..74909)
                     /locus_tag="ACL8CG_000189"
     CDS             complement(74421..74909)
                     /locus_tag="ACL8CG_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGS1342862.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAGVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(74899..75108)
                     /locus_tag="ACL8CG_000190"
     CDS             complement(74899..75108)
                     /locus_tag="ACL8CG_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1342863.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(75494..76222)
                     /locus_tag="ACL8CG_000191"
     CDS             complement(75494..76222)
                     /locus_tag="ACL8CG_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1342864.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLGFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(76238..77108)
                     /locus_tag="ACL8CG_000192"
                     /pseudo
     CDS             complement(76238..77108)
                     /locus_tag="ACL8CG_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(77465..78193)
                     /locus_tag="ACL8CG_000193"
                     /pseudo
     CDS             complement(77465..78193)
                     /locus_tag="ACL8CG_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            complement(78453..78764)
                     /locus_tag="ACL8CG_000194"
     CDS             complement(78453..78764)
                     /locus_tag="ACL8CG_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGS1342865.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(78779..80065)
                     /locus_tag="ACL8CG_000195"
     CDS             complement(78779..80065)
                     /locus_tag="ACL8CG_000195"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGS1342866.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            80662..81246
                     /locus_tag="ACL8CG_000196"
                     /pseudo
     CDS             80662..81246
                     /locus_tag="ACL8CG_000196"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            81243..82433
                     /locus_tag="ACL8CG_000197"
     CDS             81243..82433
                     /locus_tag="ACL8CG_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGS1342867.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(82947..83939)
                     /locus_tag="ACL8CG_000198"
     CDS             complement(82947..83939)
                     /locus_tag="ACL8CG_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1342868.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIREEVVQNSTYSMADYVSIYTSYIVSANGEKFSPYQTLTANSL
                     CTFDFDNIRDDFLFLLHENSYYLCVSIGFKRELLEKHLSSININPESFYGALLQTNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELSIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            84099..85853
                     /locus_tag="ACL8CG_000199"
     CDS             84099..85853
                     /locus_tag="ACL8CG_000199"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1342869.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     TLLALTIIGGLILGAMMGEQEFMKIYQEALSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            85837..87558
                     /locus_tag="ACL8CG_000200"
     CDS             85837..87558
                     /locus_tag="ACL8CG_000200"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1342870.1"
                     /translation="MKEFYKKRFALTDRGARNLSKATLASFFVYCINMPPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVKGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFNKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            87569..88153
                     /locus_tag="ACL8CG_000201"
     CDS             87569..88153
                     /locus_tag="ACL8CG_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS1342871.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            88153..88848
                     /locus_tag="ACL8CG_000202"
     CDS             88153..88848
                     /locus_tag="ACL8CG_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1342872.1"
                     /translation="MPTFSSNAPFNPNPISKILVIFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            88836..90200
                     /locus_tag="ACL8CG_000203"
     CDS             88836..90200
                     /locus_tag="ACL8CG_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1342873.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGKIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(90655..91940)
                     /locus_tag="ACL8CG_000204"
                     /pseudo
     CDS             complement(90655..91940)
                     /locus_tag="ACL8CG_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730289.1,RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(91960..92055)
                     /locus_tag="ACL8CG_000205"
                     /pseudo
     CDS             complement(91960..92055)
                     /locus_tag="ACL8CG_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608003.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        27904 a        19864 c        16895 g        27496 t
ORIGIN      
        1 catttgaacg atttcaaatc cttctttttg gtaaagattc tgagctcttt gatttgcctc
       61 gaagacattt agagaaatac tatctatatc ttcattttca aaggccaaac taacaaattt
      121 ccttaaagcc tggctaccta agtcttgctc ctgtttctgg gggttgataa aaaatctccc
      181 gatatgaaga ttgctgtctt ctagcctgat tttctggata agtcccacaa actcttgttc
      241 atcaaagatt gaaaagactc cttccaaggc ttgaagggtc agtagaaaag gaatccttgg
      301 tcccatccat tgttcttgaa aggatttgcc tagggagttg gaccactggc atacaaattg
      361 agcgttttct atactcacct tttcttcaaa acgaattgtc atcttttcct caccatctta
      421 tctatgtttc tccattatac tatttctccc attttttacg aatagataag tatgattgat
      481 ttttattttt ttctcgtcgg gagcattctc gcttcctttc ttggtttggt cattgaccgt
      541 tttccagaga aatccattat cagttcagcc agtcactgcg attcctgtca gactcgcttg
      601 cgtcccttag atttgattcc gattctctca caggtcttca atcgctttcg ctgtcgctac
      661 tgcaaagttc gctatcctgt ctggtatgcc ctctttgaat tagtcttagg actcctcttt
      721 ctgctttact cttgggaatt gctttccttg gggcaagtcg tcctaatcac cgctggtttg
      781 accttgggta tctacgactt tcaccatcag gaatatccct tactggtctg gatgactttc
      841 cacctaatcc taatagcttc ctctggctgg aatctggtca tggtctcctt ccttgctctt
      901 ggaattttgg ctcattttat cgatatccgc atgggcgcag gagatttcct ctttttagct
      961 tcttgtgctc tcgtctttag cgtaacggag ttactgatct tgattcagtt tgcttctgcg
     1021 acgggtatcc tggcctttat cctgcaaaag aaaaaggaaa gacttccttt cgtgcctttc
     1081 ctcttacttg ctacttgttt gattattttt ggtaagctac tgcttgtctg ataaaatcca
     1141 atttctgcca tatgtccttc atgaaattat ttcacagtta aattataaat tatttctttt
     1201 gtacaaaggg atgatgttat caaatcgatc tgttcttcta tcttcttgat actgatcaaa
     1261 aaatttcatt tcgactgaaa atatttcgct tataaactgt aaacgaatac tttgtttaga
     1321 cattatagtc gctagactga ctagatgatt actcaaaacg acgtccagaa tactctttac
     1381 tttgcttggt tttttaacaa aaatttgatc atccaaaggt tcaatcattt tgtaaccttt
     1441 ttgcgcaatt tgacgataaa agtaagaatg ttgctttgga gtcaataatc ctaacttaaa
     1501 agctcgatac tctaaagcct gtatcgaaac attcaaatcc gacttcaata aaatataact
     1561 atcaggattg ctgacacgct tgccaaccct ctcttcaaat ttgactaaaa actcttcttt
     1621 tggcaataaa aaacatgatg caaaataatt tgcttcttgc tccaaacgat cgccatcttc
     1681 attcatatct ttatatttat gtaaaagaat atgtcctagc tcatgagcta agtcaaaatt
     1741 tcgacgtaca gatgatttat tcgttcccaa cacaatataa ggtcttccca attttgacca
     1801 tgcgctataa gcatcagctt ggccattaat taatcgttcc acgatataga tgcctgaacg
     1861 ttctaattta taaagcaaat catgattatc ttttgaaata cctaattttt ccctggcata
     1921 aagagccaat tcctcaatgg attctccctt atgataagat tcactcacta cattacttag
     1981 gtcatgaatt ataatattag gtataattac aaaactttca aaataatcaa tcaaactatc
     2041 taccttatgt aaatacatag tttgaatatc tattgttttc cgtgttgcta ggtctgcatt
     2101 tctaaaggca attacagaag aatcaaatcg aatgctctct tcttcctgtt caaaataagt
     2161 taaatcaaca tgaaattggt tggccaaatg cattttggtt gataatttag gtttcgtttc
     2221 gttggactca aactgccaaa tggcttgttc cgttaaatta attctctgag ctaattctgc
     2281 tctacttaaa ccatttaaca gccgtaattc tttcaatacc cgaccattaa acatttacat
     2341 actccttact acttttgacc ttcttgtttt tctattcttg gaataatttc aaaatcttct
     2401 gtttccgata attctgaaaa attaggaata tcttgatatt tagcttcttc gaaatggtac
     2461 gaacttgatt gaatatactc agacaaatct tgaatcaagt gtaactgacc agttcgtgca
     2521 tcaggcataa caacatctac agatataata ttgttttctg agtccgcctc ataagttaaa
     2581 atcataaatt tttcgatatt cgaattttta gtagcttgtt caatttcttg aatcatttca
     2641 tcagaaacta actccatctg aattggaaag gaatgactat tttcatcatt tttgtaggaa
     2701 gaatgttgat taagataaag tgtattcatc tgagcatatt caaataagta gccactctta
     2761 tttttttgta ccaaaggaaa ttggttcgta agtcgcttct taccctttat aattaacaat
     2821 actttcccat atttttctgt atttgtttca aattctaaat atccccaagt ctgtcctgct
     2881 aattgtaatt tatactcaaa caaatctgct gatgcaaatg cagtatcaat atgattaggt
     2941 cgcgtccatg cataaccatt cgacactatc attgtctctc ttttttctag acgttcatct
     3001 acataatctt tttgcccttt catcaaagta tctacaattt tttgtgcctc aagcgaatca
     3061 aagagatcct gattcaacat aattcttcct cctccaaata ctttttaatg aattatatca
     3121 ttttcttaaa gaaattacta caataattag ctttttctta aagttctgtg tcagagtaat
     3181 ttagaaaatt atatcttcta tagtaaaatc aattaaaaac tgaacaaatt tattgggaaa
     3241 ttcaaatcgc tttctgaaaa tattttagga accgtagtgt aatattccag attcaattca
     3301 ctataaaact gacctttctc ctgcaaaaga aaaaggaaag acttcctttc gtgcctttcc
     3361 tcttacttgc tacttgtttg attatttttg gtaagctact gcttgtctga taaaatcctg
     3421 aatcggctct ccttggtgga gagcttttac tatttttgaa ccgacgataa caccatctga
     3481 caccgcattg aagcgttcca gatcggcttg actagataca ccaaaacctg tcaagactgg
     3541 gatgtcggcc acttgatgaa gttgcgccaa gtgcttgtcc aaatctgcac ggtaattgcc
     3601 tgatttccct gtcaccccat tgatggcaac ggcatagacg aatccctccg ccccttcaat
     3661 caactctttc tggcgctcaa ttcctgtggt caagcttact aaaggaatca aggcgatatc
     3721 tgtatctgcc aaaaatggtt ctacaaagtt ggcatgttca tgaggcaggt ctgggataat
     3781 caagcccttc acagctgtat cagccagatc tttgacaaag ttctccacac cgtactgaaa
     3841 gagggggttg aagtaggtca tgatgaccag tggaatctct gtttcaatgg ttttcaaggt
     3901 ttcaactaaa gcctgggtag aggtcccgtg ggctaaactg cgcaagccag cttcttcgat
     3961 aacaggtcca tctgcaacag ggtctgaaaa gggaatcccc acttcaatag cagagacacc
     4021 caaatcttct aaaaagtgaa ttgtttcagc aagaccgtcc aaaccttttt cgtggtcacc
     4081 agccatgata taaggaacga aaattccttt tccagttact tttatagcat tcaatttttc
     4141 tgttagtgtc ttaggcatga gcttctccct tctttgctgc atctgcttcc aagcggtctt
     4201 tgacttgaac cacatccttg tccccacgac ctgataggca gacaatcata gacttttctg
     4261 gtccaagttc tttggccaat ttcaccgcaa aagcgatagc atggctagat tccaaggctg
     4321 ggataatccc ttccacacga gacaagagtt gaaatccttc caaagcttct tcgtctgtca
     4381 cagggacata gctggcacgt ttgatatcgt ggtagtgaga atgctctgga ccgataccag
     4441 gatagtccaa acctgctgag atagagaagg cttcaagaat ttgaccatgg gcatcttgga
     4501 gcacatccat gagagaaccg tgaagaacac ccggactacc cttggtcaag gtagcagcgt
     4561 ggtgctctgt atccacacca agccctgctg cttcagttcc atacatagct actgactcat
     4621 cttctacaaa gggatggaag agcccgatag cattcgaccc accaccaaca caggctacta
     4681 gggcatctgg cagatctcga cctgtcaagt cacggtactg ttgtttagcc tctcgaccga
     4741 tgacactttg gaagtcacga acgatttctg gaaatggatg aggccccaag gcagaaccaa
     4801 ggatatagtg ggtatcgtcg atattagcca cccatgaacg aagggctgca ttgaccgcat
     4861 ccttgagcac gcgcgaacca tctgtcacgg cctcgacctt agctcccaaa agctccatac
     4921 ggaagacatt gagggcttgg cgtttgacat cttcctcacc catgtagatg gtacattcca
     4981 tgttaaagag ggccgcagca gttgcagttg ccacaccgtg ctgaccagca cccgtttctg
     5041 cgataatttt ctttttaccc atgcgtttgg caagccaaac ttgtcctaag gcattgttaa
     5101 tcttgtgggc tcctgtatgg ttaaggtctt cccgtttgag ataaatcttg gctccgccga
     5161 tatgctgggt caagtttttt gcgtagtaaa ggggagtttc acgtcccaca tactggcgca
     5221 aaagctggtt taattcctct tggaaacttg ggtctgcctg actttcacgg taggccttct
     5281 ccaactccaa aactgctgtc atcaatgttt ctgggacaaa acgtccgcca aattttccgt
     5341 aaaatccatc tttatttggt tcttgatatg ccattcttta ccctctctat aaatcttcta
     5401 atcttttcat gatctttttg tccatctgtc tccactccgc ttgatacatc tactgcatag
     5461 ggagtaaagt gttgaattgc ttttactaca ttatcttcat taaggccacc tgcgataaag
     5521 aagggctgtg ctagtccagt cgtatccagt tgaccccaat caaagggctg gccactccca
     5581 gccacagggg catcaaagag tagatagtct gcctgagaat tgggcacatg accctctcca
     5641 tctacctgca cagcctgaat gctagcacaa ggcaaattct caaataaatc atctgccacc
     5701 tgaccgtgaa cttgaaccaa gtccaagcca actttgtcaa tcgcttccag cagttctgcc
     5761 cgacttggtg aaacaaatac accaaccttt ttgacatctg caggaataag ctttgccaac
     5821 tcagctactt cttctaaagt tacctgtctt ttactaggtg caaagacaaa accgatatag
     5881 tcggctcctg ctgaaacggc tgtttccacc gcttctttgg tcgatagtcc acaaatttta
     5941 acctttgtca atctgcaact ccttgattct ctgggccaca ttttctgcct gcataagagc
     6001 tgtccctacc aaaattccgt taaagtatgg ggctagtcgt tccgcatcct gccctgtgaa
     6061 aatggcagat tcagaaatgt aatagcgacc ttcctcaaag taaggggcta aatctacact
     6121 ggtctgcaag tcgacctcaa aggtagtcaa gttgcggttg ttgaccccga taatctcagc
     6181 accaagtctg tgggctacct ctagttcagc tagattgtga gtctccacta agacttccag
     6241 accaagctct gtcgcgtagt catacagttc cttgaggcgt tcttcggaca aggctgccac
     6301 aatgagcaag ataactgtcg cacctgcatt gcgagcgcgg atgatttgct tttcatcgat
     6361 gataaagtct ttgttgagcg tcggaatctc tacctgactg gaaatttccc gtagataatc
     6421 caaatgccct ttaaagaaaa cctcatctgt caacaccgaa atcatcactg ctccgttttc
     6481 ttcataagtc tgggcctgtt gcacaatatc cacatcgaga ttgatatctc ccaaactagg
     6541 gctagctttc ttgacctcag cgattacctg caagcggtcc tgatgattct tcaaaaactc
     6601 tgccaagcga taggtctggc gcagaggctg gatttgctcc agcttcatct gctccacctc
     6661 acgcaccttc tgctctaaga ttcgtgctaa aaattcctga ctcatttttg gtactcctgt
     6721 aacagtctga gtttttcaag ggccttgcct ctagcaatca cttgacgggc caaggcaact
     6781 ccttccttga tgctatcaat cttaccatta gcatagaaac caagaccagc attcaagact
     6841 gtcgtttcca agaatggact tgcttcgttt ttcagaacgc taagcaaaat ttctgcattt
     6901 tcctgagcat tcccaccacg aatatcttcc atagcatagc cttccattcc caaatcctct
     6961 ggagtaaagc ttgacaagct gatttcgcca ttttcaagaa gtgcaatctt ggttgttccg
     7021 ttcaagccag cttcatccaa cccttctggt ccagcaacca cgatggcacg tttgcgaccc
     7081 atatttttca aaacctgagc tgtactttct aggagttctg gacgactaat tccaagaagc
     7141 tgtgtttcta aagccattgg atgaatcagt ggaccagtca agttcataat cgttggaatt
     7201 cccaattcca aacgagctgg catgatgtat ttcatagctg ggtgcatatt tttagcgaag
     7261 agaaagacga ttccagtttt atcaaagacc ttacctagtt cagctggttt gaggtcaaga
     7321 ttgattccca aggcttcgag gacatctgcg gaaccagatt tagaagaaat cgagcggtta
     7381 ccatgcttgg ccatgtgaat accgccacca gccaagacaa aggctgcagt tgtggaaata
     7441 ttaaaactga aagacttgtc cccacctgta ccacagttgt ccatggcatc atgaatctca
     7501 gttggaatat gctgggcatg tcctctcatg acttgggcaa tggctgtgcg ttcttcaggt
     7561 gtttccccct tcatcttaag agctaagagg agagaagcaa tctgcgcttc agttacacgc
     7621 ccagttacga tacgctcaat gacatccgtc atttccacac ctgataaatt ttcaaatttt
     7681 gctagttttt caataatctc tttcatccta gtttcctcac tttacaacct tctcgataaa
     7741 attccgaata gaagacaagc cgtctggcgt tccaatgctc tctggatggt actggaagcc
     7801 ataaatcggt aggtttttat gttgaatccc catgatggct tggtcatcag tcgaacgagc
     7861 tgtcacttca aagtcttctg gcatttcctc aatcaaaata ctgtgataac gcatgaccgc
     7921 acgtccttcc tcaatacctt gatacaaaac agatggcgct tcaaagttga tattgctctg
     7981 tttcccatgc atgacttttg gagccaaacc tagcttacca ccaaagactt ctgcaatggc
     8041 ttggtggccc aaacaaatcc caagaatcgg cttcttgcct gcaaaatcac gaatcatgtc
     8101 ttccatcttt ccagcatcaa ctggccaacc aggaccagga gaaaaaacca gaccatctgc
     8161 tttttcagct tcttcataca gcttggaatc atcatttctc agaacctgaa cttctgcaaa
     8221 attcccaatg tattgggcca agttataggt aaaagaatca tagttgtcaa tcaataaaat
     8281 catggtctta gttctccaat tctagtcata gattttgctt tgttaatggt ttcttggtat
     8341 tcgttttggg cgatagagtc gtagacaatc cctgccccag cctgcacata ggctctttga
     8401 tttttgagaa tcatggttcg gatggcaatg gccaaatcca tatcacccgt cgcagacaag
     8461 tagccgattg ctcctgcata tacgccccgt ttttccgttt ccagttcata gatgcgtctc
     8521 atcgcccgaa tctttggtgc tccagaaacg gttccagcag gaagtgtagc tttcaaggca
     8581 tccatggccg tgagttctgg aagcaaacgc cccttgacca cgctggtcaa atgcatgacg
     8641 tagcggaaga gctccacctt catatactta gtaacttgga cactggccgt ttcagagatg
     8701 cggccaatat cgttacgccc caagtctacc aacattcgat gttctgctgt ttccttctca
     8761 tcagagagga ggtcagtcgc caaggtcttg tcttcttcat ccgtagcccc tcttggtcgc
     8821 gtccctgcaa tcggattggt tgtcacgatg ccatttttga cagaaactaa actttctgga
     8881 ctagctccga tgatttgata atccccaaaa tcatagaaat aaaggtaatt agaaggatta
     8941 gtcacgcgga gatttctgta gaagtcaaat ggatttccag taacttctgc tgaaaaacgc
     9001 tggctgagta cacattggaa catatctccg ttacgaatca agtcacgagc tgtttctacc
     9061 attccctcaa acttatgtgg agcgatatgc ggtttgaagt ctaacggaga tagatccaaa
     9121 tcttcaaatt catttggagc aggaatgcgt aattcctcaa gcacttggtt caaggatttt
     9181 tccaaggcct cttgactgcg ctcactataa agtgcatcct ctatgacatg tatcttctcc
     9241 ttcttgtggt caaagaccat atagctctca tagacaaaga aatgcatgtc tggcgtccca
     9301 attgtatcct cagggatttg accaatttct tcataaagcg aaatcatatc gtaacccaca
     9361 aaaccaatgg ctccaccacc aaaaggtagc tctgagtggt gctgactctt atgaatcact
     9421 tcataaagga aatccaaggg atcccgatca atcacttgac cattttgata gagaacccca
     9481 ttttcaaact taatctcaaa aactggatta taggctagga tataaaaacg agctgtttcc
     9541 ttgtctctcg gaatactctc taaaataacc ttatgttgcc cctttaagcg catataagcc
     9601 aagattggtg ataagacatc tccatgaatg attcgttcca ttgtaatttc cctttcagtt
     9661 ctacttctag tccgtggtga ctgtatgaaa aatccccacg caaaataact tgcgtgagga
     9721 cgaaattcgc ggtgccacct caattatagg atttctccta tctctcattc ctgtctcaga
     9781 tatctcctgt aacaggctgt gcgataaagg gcactccctt gagaatgatg ttttcttctc
     9841 tcgtttcaga tgaacccaac tttacagctt tctctgcttg ttttcagcaa ccacaagctc
     9901 tctgtgagag aaagaactgt aatttttcca tctattattt tttagcttct agtaatctgc
     9961 aatcgcagct aggtccttgc ctccacgacc agagacattg atgaagagat gttcatctcg
    10021 gtacaccttt atactcttcg aaaatctctt caaaccgcgt caacgtcgcc ttatcgtagg
    10081 tatggttact gacttcgtca gttctatctg caacctcaaa acagtgtttt gagctgactt
    10141 cgtcagttct atctgcaacc tcaaaacaat gttttgagct gacttcgtca gtcttatcta
    10201 caacctcaaa gctgtgcttt gagcaaccta cggctagctt cctagtttgc tctttgattt
    10261 tcattgagta ttacagtgaa caatttttct agctattgta acaaaaaagt cactcgaagg
    10321 caactttttt cgtccataaa ctttcaaaag agaatggctt attcagaact aaaagccgca
    10381 gctttttgca tttggtaata cttacccttt ctatccatga gttcttgatg gttaccatat
    10441 tcaacaatat caccatctac taagacaaga attaaatccg catcctgaat ggttgacaaa
    10501 cggtgagcaa tgatgaagct tgtgcggccc ttcatgagtt ttgcaaaggc atcctgtacc
    10561 agcacttctg tccgtgtatc aatggaagaa gttgcctcgt ctaagataag aatctttgga
    10621 atagccagaa agactcgggc tatggtcaag agctgagctt ggccgacaga gagagattct
    10681 ccagcatttt ccaacttggt atcgtatccc tgtggcaact gttggatgaa aaagtctgca
    10741 ttagctgctt tggcagcagc aattacttgc tctcgactgg cttcaggatt gccaaaggca
    10801 atattatcat gaatggtccc ttgtgtgagc caggtttctt gaagcaccat accaaactgc
    10861 tgtctcaatg atactcgtgt ataatcataa atggattgcc catccagcaa gatatctccc
    10921 gagctaatgg gataaaaacg cataaggaga ttgataagag tcgattttcc agcacctgtc
    10981 ggaccaacga tggctacctt actaccagct ggaatatcga tagacaagtc cttaatcaaa
    11041 attttttcag gatggtagcc aaaagagaca tgtttaaagg aaatagctcc cttaacttgg
    11101 tcactggtca agacttcctt acctgtttca gccacttcag ggctatctaa gactccatag
    11161 atacgctcta cgcaagccag agcactttgc aactcagcta gcactgaaga aatatcgtta
    11221 aagggcttgg tgtattgctg aacatagttc aaaaaagtca ctaaacgacc gacggtcaag
    11281 gttgaaccca tcatgatacg ataagctcct actccagcta aaagggcata aatgagtgca
    11341 tttacaaagc gagtcgaagg attgaccgtt gaagaataaa agatggctga ctgagaatag
    11401 cctgagtagt tgtcatgagc ctcacgcaat ctttggataa actctgtttg agcattgaag
    11461 gactggatta tagtctgctg gctaagcgat tcttcaatca aatgggtctg aatccccctc
    11521 gtctctgttt gcttctggaa gagatgatag gatctcttgg caataaagcg tgaaatcacc
    11581 atggacagtg gcgtcaacag caagactaag agagtcatga ggagatgaat ttggagcatg
    11641 gctagaatac taaccaaaat catcaaaaca ccaatgaaaa attggttaaa aatcatggtc
    11701 aagccagctg ccaactgttc gatgtccgtg gttacacgac tgaccatctc tccattgcct
    11761 tgccgatccg caaaagcaat cggtaaccga tggagtttat ggatgattcg ctctcgtaaa
    11821 tctctggtat aagagaagat tagacgatta tagaggagag gattggccca ttgtaccaga
    11881 gtatttccta ttaccaccaa gagcatctgg agaaaaatct gccaaaaaat tggtgatgaa
    11941 ccagccacta ggacttggtc aatgacctgc ccaatcagaa taggtaggta aattgataag
    12001 ccaacttggg caatagttcc tagaaaagct aggaaaagga ggaagggatg gtttgctaaa
    12061 tctacggcta aacgtttgag cgtctggttt acagtttgtc gtttcattct agtcctcctt
    12121 tccatgttgg gatgcattga tttcacgata gacttggctg gatttcatca agtcatcgtg
    12181 cttgccaaca gctagcaact cacctttttc caagaggaga atctggtccg ccatctgtaa
    12241 agttgaggtt cgttgagaga tcaaaattaa gctcgtgttt ggaaaatttt ctctaatagc
    12301 tttcaagagc ttggactctg taatggtatc tagtgccgag gttgcatcat ctaggatgag
    12361 aaacggagct tggcgcaaga ctgctcgggc gatagacaac ctttgttttt gtccacctga
    12421 gaaatttcgc ccccctgctt caactagagc atccaagagt ccttccttat cactgacaaa
    12481 atccttagct tgagcaattt ccaaggcctg ccagagttct tgatcagtca cttcttgatt
    12541 gaaacctaga gtcaagttgg aacgaatggt tcctttaaag agttcgacct tttgaggtac
    12601 agaggcaatc caagaccgcc actgctccaa attaagagga ctacgtccat tttgataaag
    12661 gtcaatgttc cccttgtcta ctggataaag tccaagtaag agttgcacca agcttgattt
    12721 accagaacca gtccccccaa tgataccaag gatttgtcct tgagtcatat caaaggaaat
    12781 gtctctcaga gaaggctggg ccgcatcagg ataggtaaag gtcaattctt ggacttgtaa
    12841 aacccgatca ctggtaactt gcttttgttc taattctgaa tggatatcct ctggagcctc
    12901 aacaaagact tccttgattc gcttggctga gatataggac cggttgagag aattgatcaa
    12961 catggctagc ttgaccaatt ccaccaaaat ctgtaagagg taattgataa gagcaatgag
    13021 agcaccttga ctgagcactc ctccttgaat tgaaatatag ccttgccaga taataacgag
    13081 aagagttcca ttgacaatca gataggtcag aggtgttaat aaactagacc agaaacctgt
    13141 cttttcttgt aatctagcat aaacttggtt aagggtttga aaaatctgta actctcgttt
    13201 ttcttgacca aaagcacgaa taacccgcat cccttgcaat tgctggcgcg tttcctgaac
    13261 cagttggtcc gttttctttc tgagactact gtagagagga ttgaccaatc gcgataaccc
    13321 tacaatgaca atggtcaaaa tggcaaccat gactaagaac cagaaagtca actcagctga
    13381 gattcgataa gccataaaaa tggcaccaaa aacgataatg ggcgctcgta aaaagagacg
    13441 caggaattga ttgataccag tctgaatctg gtaggtatcc gaagtcaagc gagtgaccaa
    13501 actagaagtt gtcagacggt ctctgctgtc cttgggcaag gaaagaatat gacgataaag
    13561 atcgtttgtc aattccttag caaaacctac tgctgccttt gctgagtaaa attgagctat
    13621 caaggccact aaaacgccaa ttactgcaaa gataaggagc agaccaatct gcatccagag
    13681 atgaccttga tctccctgag gtaaagattg gtcaacaatc ccagcaatca ccatgggaac
    13741 caagagctca aaaacagctt ctaacagctt gaacaagggg gctaaaattg attccttgat
    13801 gtagggtttg aagtaagata ataggtgttt cataaatccc ttttattcat attctagaaa
    13861 tgaagaaagt gggaaacccc accctctctg ttttatttgt ttaagtaagg caatagatag
    13921 ccatatcctg ctttttccat ctcatccttg gccacaaagc gtaaagaagc agaattgata
    13981 cagtaacgga ggccgcctaa ctcccgcggt ccatctgtga aaacatgacc caagtgagcg
    14041 ctgcctgaac gagaacgaac ttcaattcgc tccattccat ggctcagatc cttgtaataa
    14101 tgaatcaact ctttggaaat cggacggcta aaacttggcc aaccacaacc tgaagcaaac
    14161 ttatccttgg caaaaaagag tggctcacct gtcgtaatat ctacataaat cccctcttca
    14221 aaggtttggt cataggcatt ggtaaatgga gcctctgtag cagcttcttg tgtgacacga
    14281 taagactctt cagatagact ggccttcaac acctcttgac taggcttttc atagtttgct
    14341 gcatcaatca atggcttatc agcatcggtc acatcgatat gacagtaacc tgaaggattc
    14401 ttcctgagat agtcttggtg gtagtcttca gccagaatgt agtggcgtaa ttgctccact
    14461 tctactgcaa tctttcgacc cagcatgcgt tcctgctcct gcaccactgt gtagatagct
    14521 ggcaaatctg cttcatcctg ataataaatc ccagttcgat attggcgacc acggtcattc
    14581 ccttgttgat tgatagatag aggatcgata actcggaaat aataaagtaa aatctctctg
    14641 agtgacactt ccttctcatc gtaaatcact tggaccgttt ctgcatggtc tgtttccttg
    14701 agcaactggt aattggtcgt ttcgacttga ccattagcgt agccaacact ggtttctagc
    14761 actccagaaa tgcgtgaaaa atattcctct aggccccaaa aacaaccacc tgctagataa
    14821 atttctgcca tctttatttc tcctttatca cgtttttaac taatactctt cgaaaatctc
    14881 ttcaaaccac gttagcgtca ccttaccgta tatatgttac tgacttcgtc agttctatct
    14941 gcaacctcaa aacagtgtct tgagctgact tcgtcagttc tatccacaac ctcaaaacac
    15001 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa
    15061 cttcttttca caaaaaggat atgaaaccct ctggtcaaga gtttccccat cctatcttct
    15121 attctttatt ttgcttctac acggacacct tgggtatcaa ctctcaagtc atgcagtttt
    15181 cctttgaaag gttgcttttc caattctgcc ttaattgttg gcatcttgtc atgagaagcc
    15241 agaaccataa ctgtcggccc agcaccagaa aggtaggttg cataggctcc attttctttg
    15301 gtcacttgct taatcatcgc aaattctctt accaagtcct gacgatagcg ctcatggaag
    15361 aggtctccct cgattgcttg cccagcggtc accatgtctc ctgccaacaa ggcagcaacc
    15421 gctacattgg cgatagaact tgcagcaaca gcttccttat aagacaattt tttaggcaag
    15481 acactacggc tgtcgcgagt acgtaattca tagtttggaa tgtaagctag aaaatcacac
    15541 tctggaaagt ctgctacgat agcagagact tgcccttcaa cagaacttgc aataacgaga
    15601 ttaccataaa tggctggagc cacattgtca ggatgccctt caatcttggt cgctaactgc
    15661 aatttttcat ggtctgataa gttgagttga cccagttggt tggctagttc aatcccagca
    15721 acgataaccg agctggaaga acccaaaccg cgcgccaaag ggacatcact ggtcattttc
    15781 aagcgtcttg gttgcaagtc tggtacaatt tgtaaagcga ttttgagcaa gagattacgc
    15841 tcatcatgtg gaatccattt gccaatctgg tgttcaatca gccactcatc tcgttcttcg
    15901 cagacctcaa tttgaagata cttggttaca gctacaccga ccgagtcaaa acctggcccg
    15961 atattggcac tggttgcagg tacaataatc ttcatcttat tctcctagca ccttgaaggt
    16021 attcaagagg tcgaattctg aaaccttctt caattcagct gagacatttt caagctgggc
    16081 tttattaatc ttgtgtgtga tgataacgac acgcgccttg tcaccctctt tgccatcttg
    16141 aaggatttgc ttaaaggaaa tatcttgagc attgaagatt tcagccaact tcaagacctg
    16201 accttttgag tctagagcca agattgagaa atagtagttt gctttgacat cttcaggatt
    16261 tgccaagacc aagtcacggc tatattcgtt gaagtctttg ccaatagtac catcattcaa
    16321 acgacgaacg atacggacaa tatcagctac aacacttgtt gcagttggtt tttgacccgc
    16381 acctggtccg tagtacatag actcaccaat accgatagat tctacaaaga cagcgttcat
    16441 tacgccattc acactagcaa gtgggtgcgc tttaggtagg aaggttggag tcacttctgc
    16501 agcaatacct gaagaagttt cctcaataga accaaccaat ttcactacgt aaccaagctc
    16561 ttgagctaca gctacgtctt ctggtgtgat attgcggatt cccttgtggg ctacatcatc
    16621 aaaggcgatc ttcatgccaa aggcaaattg gctcaaaata accatcttgt aggctgcatc
    16681 aatcccatct acgtcattcg tcggatcgct ttctgcaaat cctagacgtt gtgcttccgc
    16741 aagagcatca tcgtaagacc agccttcttc caccatcttg gtcaccatga agttggaagt
    16801 tccgttgact actccaagca cgcgcgtaat tttatcagaa gccaaggaat ttgctaaagt
    16861 acgaagaatt ggaatcccac cagcaactgc tgcttcgtag taaagtgcta ccttgttagc
    16921 ttgagcgatt tctagcaatt ctgcgccatg gacagctaaa aggtccttgt tagcagtaac
    16981 aacgtgtttt ccagcttcca aggcacgagt gataaaggtt ttagcaggct caatacgccc
    17041 catcaattcc actacgatag taatatcctg gtctgataaa atatcatcca cattggttac
    17101 aaagttaaag tcattccctg ctgcaagcaa gcgatttttt tcatcttcat ccttgaccaa
    17161 taccttagca actttgatat ctgaatgtgc tgattgattg atttttcctc cattttcctt
    17221 taggaggaaa ggcacaccac ttgcaacggt accaaatccc agtaaagcaa ttttaactgt
    17281 catctttatc tcctcgaaat tttctaatat agccattata acagaatttt gtgaaaattc
    17341 ctattatagt aaatcactat ttcagtataa aaagaaaaaa cgaatcagac gattcgctct
    17401 tcttaaaatc tgaaaatagc tttccagaaa ggattagccg attttttgca gattgagcac
    17461 tgcatcgtga ctcatcaaga cttgaccata ctcttgtaag actgagcgac tgatatcact
    17521 atcgtctgca aactcgcgca tacgggccaa cagccaagct ggatatgggc ttggatgatt
    17581 ttcaatatcc actaaaatgg tcaaataata gcgctcgttc attttgtaga gttcagaagt
    17641 ttccatttca aaagtcactg tcttggcaaa aactaccaag tcagccaact tagcaaaaga
    17701 aaggatgtag tagatgtaag gttctttctt actctcagct tcttgttcag cctgctcttg
    17761 ctcttcttcc ttggcttcaa cttgctcaag agattgaatg gcttcgatat catccttggt
    17821 tttgtctgcg atgctttttt ccagggtttt gataaattca tctggagaca tttgagccaa
    17881 ttcttccata tctggcaaat ccgataagtc ttcaaaatct agattttggt caatctttga
    17941 cttggtcaca aagacatcta ccttatcagg ttttggagtc acacggaagc tcaacatgcc
    18001 tgtatccaga aagctatcag gcatctctag ctcatccaag atagcataaa agaactcttc
    18061 tgttttttct tgaggaacga gaaagtcagc aatctccatt ccacgatcca tcaaatcctc
    18121 taaagacatc gtgattttta aagttgtatc actaatttgt ttcattttca ttgctagtaa
    18181 cctcatactt tcagttctat ctattatact agatttttac gattttatca aaagaaggct
    18241 cctctatacg gatagatttt ccctagggtc tttctatagg agactccaag agaaaatttc
    18301 tgcagacaga tagaaaaagc cttcaaaatc ggctaagagc cgattttgaa gaccttatac
    18361 atcagaatac ttataattta aaggttgcta caccgaggat agaacgattt aagtttctga
    18421 gaatttgaag actttgctca aatttcttat aacgagtcac tccgtactct tcaacaagaa
    18481 ggactgtatc tctttccaaa agagatgata catcctgtaa atctacaaaa tgcattcctt
    18541 ttaaagcttc ttgactctgt ttcaatttat ctaggatagc tttatttgag ctaacgatgg
    18601 tcaattcctg tccagtattt ttgtatgaca aaacatctgc taggttagca attgttgtaa
    18661 tctctgttac aaaatcaatt tgatactgag aaaaatcacc tactctattg attgttggat
    18721 taaagagata aactaacaca tttcccatca caaccaaaat cacacaaacc actccaataa
    18781 caactaaacg aagaatcaga tttttcacat ttaagccaag cgctgtttca ccatttgcgt
    18841 tcaattcttt agagttgatg gtttccagtt tttcaatttt tacatttgca taggcatgtt
    18901 taaatttctc aatcaaccca tcaatttttt tctctaacaa gtcattggca tctttacttg
    18961 atgtcaaaat tttcacacca acccctgcat cgtcaatcat atagtagacg gtcaattttt
    19021 tccaccaata gtcattcgtt gaatttttca aggttgtttc tgtcgtgtct aattcactgg
    19081 caattttttt caactcactg ggttctacat cattgaaaag ataagctcca ttcaaattac
    19141 catcaatcaa tttcccataa aaatcactat aaccaccaat ttgatgattc aaaatcgttt
    19201 tggccgaatc ttctggagga gtgattttat agataagata agttgaataa cttgttgtat
    19261 ctttgacagt gtttttattc ctaactgctt taattgtaaa tggtacagca atgagagcaa
    19321 ataaagcgat gagagctaaa atatttgctt ttcgtttttt ataaagattt gcaaacaaat
    19381 cagctactga ataatgttca aacatgattt ttttctcctt tgtttagtag atactagttt
    19441 tcctttgtaa gcatttttgc tacaaatata atcacaagaa caattcccca gaattgcatt
    19501 gtaaataaat tgaagaaact ttctgaaaag ctgcttcttg gcataaagaa tagattattc
    19561 aagatgagta gggataaagc aaataggatt gtccttgagc gataggctac ttgcagcatg
    19621 gctataaata atatgccgag taagaaacta agcagaaaga ctccaatcat accatagtcg
    19681 gtatacaact ccatgatata actacttccg ataccatgcc ctttcaagta ttccttgttc
    19741 aagacaagat aggatagatt gtgggcataa ctattactat caatagctag ttccacacta
    19801 ttggttgtat gttcaaaggc ttttcctccg aaaatggctc ccaaactccc ccttgcaaaa
    19861 taatcaagaa caggaccaaa agtaaaatta cggaaatctc ggtaagggag gctactgtta
    19921 aatagaaaac ctcgagccag aacaccaaaa ctagtccctt gtttatagat aaagtcaagt
    19981 aagatatccc agaaacctgt atgggaaact tggacattat cccgtacata attgagtact
    20041 cccatcgcta acatgagaat aggagaacct acaaaaatcg ctaacttttc tttaaaccca
    20101 atccattttc ctttttcagc ttgctcccgc ataaagtaat aaacaaaagc aaataaaata
    20161 cttaaaataa agggatttcg tgtcccaatt gccaaatgaa tagtgttagc tgcaataaag
    20221 gagacaagca ctgctgtggc ctgcaatttc tttggcttgg ttgccagata catacacatt
    20281 gcatagaccg taaaggtaga caaaatgtag gtaaaataag gcagtttact ttcaaaattt
    20341 gcatagtagg catagtagga agtctgcaaa cgatacaaga gccgttcaaa taaccgaatg
    20401 aaatagaaag gataagttag aagaaaaact cctagtgata caaagcgtaa ccgcttgata
    20461 taaacctctt ttagagaatt tcctatattt gctactttta ttttcttcct agctatgaag
    20521 taacgagcca ggacgcctcc tgttgtcaag cccagaatcg aaaccatgac aactataaag
    20581 gcaaaacgat aggctattgg atgataggta tccaaagcac catccctaaa ataatcaatg
    20641 gtcggtcttg ataccagaaa tacaaaaatg gttaaataga aaataaaatg gattaagtaa
    20701 tacttgatat cattccaaca agcaatcaag ctactaacca acaagaacaa taaagtagaa
    20761 agtaagctaa cattattatt attaaacaga tacacaattc cacttactag cgtcaaggca
    20821 taactgacta tggtcaaact aaataataat cgtttcccat caatcacttg gtcacccccg
    20881 ttctaatgta attttttaga tttttcaata tttttcagta ataagaatcg gtataaggaa
    20941 atatttatga atagggccaa agcactaatt cttctcccct tacggaaaat tgaattccta
    21001 gaaatagcaa aggcatggcc ttttaaaaaa cgatgaatct gagaataggc ttcaaactgt
    21061 ttatactgat catctagcaa catcttatcc agaataaaga agtgggcata ggccaatctg
    21121 aaaaaagcga cctctttcaa gtcaggatag tttttcacaa cttcattata aaacttttgg
    21181 tagatatcaa tataggctaa atccttctct gcatagggct tggtcgtaat actatcccct
    21241 ctatggaaat agtaataata gggtttagta ttaaccacat acttcttggc caacttgatt
    21301 aaatcaaaat ggtaataggc atcttcgtaa atcaacccct taggaaagga taggtcagtt
    21361 gcaatctgtc tcttgattag cttattgcaa atcgtcccag gtattttttc acctatgagg
    21421 tattccttta gaaatgtttg agaatcacag acaaaatagt catcctgatt ggctgactgt
    21481 gggctttcat cattagcata gacattcatg acaccacagc tcgaaacatc cgcatcttct
    21541 tgaactaatt gctcatataa gctctgaatc atttctggat ggatataatc atctgagtca
    21601 ataaaaatca gataatcccc gtgagcctgc ttcatcccat catttcgtgc ttgcgacaat
    21661 ccttcgttct ttttatgaag cactgacacc ctgtcatctt gttcagcgat tgaatcacac
    21721 aagcgaccac tttcatctgt tgcaccatca tcaacaagaa taatttccag attttgatag
    21781 gtctgcttct gaatggaagc tatcgatttt tctaggtact gcgccacatt atagactggc
    21841 acaatcacac taattaatgc agtttccatg ctactcctct aatagttttt ctacttgttc
    21901 gatttgtttt gtaattgtaa attgttgaat gaattggcta gcctcatcga catcaaagtt
    21961 tgaggcagaa gtcatgtaat tagtaatcgc ctgagctgcc tcttgattgc tctcaatgat
    22021 ttgtccaaat cgtccttctt gggataattc ctcagcccct ccaacgtccg tagagataaa
    22081 agggagtccc agactcaagg cctccacata cactccagga aaaccttctt gtttagacat
    22141 agacaagaga actttcgtct gagatagata ctgataagga tttttttgat aaccaaggaa
    22201 atgtacatag tcctcaatcc catactcttt gactcgtttt ttcagttcct cttccatatc
    22261 accagccccg ataaaataga gatgatagtt ttttccctct tggtataata atcgtatcac
    22321 ttccactaca cggtcagaac ccttattttc ctcaatccgt ccgatagtac agatactttg
    22381 aggagcaatc tcgatatcga tcttctcttg agatttttct agaatagtct gaaaatcata
    22441 tccattgtag attgtctgta atttagaagc ataatctgga taaacttcct tgatagaatt
    22501 gctggtcttt tttgaaatcc ctacaattgt attcgcagca tccaactggc ttctatgtga
    22561 ttctctttta gagctatcct taagaagttc ttcaatactt ccatgaatcc aagatatctt
    22621 cttgacttct cttcttttag agaacaacag tggtggattc ataatggtaa aagaaacttc
    22681 aacatcataa tcatctttta caagcaaacg acgagtcagt cttggaaaat aaattctcat
    22741 tctccacaaa aaagctcgta accatctggt ttggcgataa tcttgaaggg attttaaaat
    22801 gcgtacatgc tttggaacag attcatatcc cttgtcaaag tgctccattt caagaatatc
    22861 aatatcatac ttttctggat ccagatttga aacaatagtt gatagaatct tctctgcacc
    22921 acctccaaga gaaaaagacc acataaaaaa taagattttt ttcttagcca ccatattctc
    22981 ccttgtattc tgtataagac ttatccatat cagcgatgac agcatcatga tgcggtacct
    23041 gcttgtctgc tggtggaggc gtcatataat ccccaaaagc agttctgaga tagacatcat
    23101 agccgattgg aataggcatc tctgttcctt caaatggcaa gaaaagattg tcttcaaaag
    23161 atgtgattgg gtacttgttt ctcatgtagc caggacctga gcataattct gtaatgccat
    23221 cacaatcagc caaatcatac ttagtcattt ctttctcagc ttttttccag atgcgataac
    23281 ggagagattt tggagtcaaa cccagtaaaa tgcaacttcc ccatttcatg agagcaccat
    23341 gcttttctgg aatagtttgc gcacaaaaga gtgaataaat caaggcccaa cgaacctgtt
    23401 ttttccgctc agctggattt ttcggataat aatccaaagg caaaacatcc aaggccagac
    23461 catgtggcaa atccaaatcc tgctgataag gcttgataca ggtggttttc ttgtcacgaa
    23521 tggtaataaa aagattacga tcaacaaaat ccttgtgact ctttgacaag aaataacgtt
    23581 catctgcata acgaggccat aattctgcta atttctcata atctttacga ggcataaaaa
    23641 agtctaggtc gtcgtcccaa ggaataaatc ccttgtttcg aagggcacca atagcgcctc
    23701 cgccacagag ataacagagc aaatcatgtt ctttacaaaa ggccacaaaa tattcagcca
    23761 tctccagact acgagcctga attgctttta aatcagtcat attgttcatt attctttcta
    23821 tcgtatcgtt tcattatacc acaaacaagg ggtgaaaatc tattgcagac tgtaaaaaat
    23881 caaagcctga ctgctatcca aatagctatc aaactttgat ttttctgtct tatactcttc
    23941 gaaaatctct tcaaaccacg tcagcttcac cttgccgtag gtataggtaa ctgacttcgt
    24001 cagtcttatc tacaacctca aaactgtgtt tttagcagcc tgcggctagc ttcctagttt
    24061 gcactttgat tttcattgag tattatctta tctcaagccc atttgagcga gcttggtttg
    24121 atatttgttt tgatcaacca gcaagcccaa gcctccataa acatcatagg catctaccca
    24181 gtcacccagt tctggaatcg tcaatttttc aataccattt tttgctccat ccaaaacaga
    24241 taaaccgttt gttaggagga aagtataagg tacgttggtt gaggtcatag caaaaacctt
    24301 tccaagagct tcagaaccag tgaaaagttt agtgggatct ttaatttgct ctaaaattgc
    24361 tgttaaaact tgttgctgtc tttttgtacg gccgtaatcc gcctcatcat catcacggaa
    24421 acgagcataa ttgagcaggg tcgagccatt catctgctgt tttccgactt taatggtttg
    24481 ggttggagac tcagtctcgg tagcatataa atcatctccg actgtagctt ctgttagggg
    24541 acgcccattc aatgttgaaa attgagcatc aatcgtcacc ccatcaggga aaagcgtgtc
    24601 aatcgctgtg gcaaaggcct ggaaatcaac caaggcgtag tacttaatgt ccaagtcaaa
    24661 attatctttc aagacttggc gaaccatttc tgcccctttt tgcccctctt gttctcctaa
    24721 ctcgtaggct acgtttaact tgttatctgt ctgttttcta ccattaatca cttgactata
    24781 accatctata tagaccaaat tatcacgcat gaaactgact agcttcattt tcttatctga
    24841 gcccccgaca tttaatacca taatagagtc agttcgtgtc tcaacactgt tctggccgat
    24901 tcgaccatca gtacccatga ttaaaatatt aactccatct ctagtgtcct gaccattaaa
    24961 gacttctact tgagctgccc gggcatcagc agttttcttt gcgctagcat cttggtaacc
    25021 acgcaaaaac atgaatacca tggccaaagc cacacagacc aaaagtgaaa aaatcaccat
    25081 aaaaattcgt ttaagacgga gcttccgtct tttctttttt ggagggaaag agagtgcttg
    25141 tgatttggat tgtgagcgac tccggttcgc atagcttggt aagtcaacct gctcttctct
    25201 ttcttgttcc aagctagagc tactatttcc cctagcaaga gttagctttt cttgcaaata
    25261 ggcaaactca tttttttctc tctcattgag atagtgaata ttttttagca aataatcata
    25321 acgcaactgc tcatgatgac ttaagggatt ttctttactc atcttctctc ctttccatgg
    25381 tctgatattg gataaatagg ataggcaccc agaattttat actggattcc aatcgcttct
    25441 aattcttttt gggcaaagtg gaccaagtcc ttatcggtat aatccacatc gataatgaaa
    25501 aagtattcac ccagtgctgt cttgagtgga cgactttcaa tttttgtcaa gtcaattcct
    25561 cgccaagcaa aggtcgacag ggccttataa agtgcacctg gaaggttgtc aggtaatgtc
    25621 aaggccaaac tcatcttttc agtttgtgct tgcaagggaa tactaggctt ttcagctcct
    25681 agaacccaga aacgtgtgaa attggcttcc atttcctgaa tatcctcggc aatcagttcc
    25741 aatccatatt cttcagcaga acttctaggt gcaactgctg caaagggctg gtctggatgt
    25801 tcggaaataa aacgggccgc ataagctgta ctagctgtta cctcgatttg agcctctgga
    25861 tattgttcat cgatgaattt ctttccttga gccaaggcct gtggatgtga aaaaatcttt
    25921 tcaatcttag tatggcctgg aaccaccatc aactgctgat gaataggctg aacgatttct
    25981 gctactgctt ggatgtgagc ctgatgaaaa agatagtcca aggtttcatg aacactaccc
    26041 tcaatagaat tttcaactgg caccacagaa tagtccacta atccttgctc ataagccttg
    26101 atgacatctg taatgttggc aaaagcctgc aattcctcat gaggaaaagc tgtctgcaca
    26161 acgtggtgtg aaaatgatcc tttgggacct agataagcaa ttttcatctt agttcctcta
    26221 taatttcctc tgggcttagc ttggtcacat ccaaaacccg actagccact tcctcatacc
    26281 aagcctgtct ttcttgaaaa atagctacta gttcttcctt gctattattt agaaaaagcg
    26341 gtcgctgatt gtccttatca gctgcgatac gttggtagag ggtttcaaaa tctgctttca
    26401 ggtagatgtt atctgtatta gtcttgagta agtcacgatt tctctgagaa ataaccactc
    26461 ctcctccagt tgacacgact tggtctgttt gtagtaaatc agctaggact tctgattcta
    26521 cctgacgaaa ggctgcttct cccttttcag cgaaaaaatt cgcaatggac atacctaggc
    26581 gcttctcaat cagagcatcc atatcaaggt aattagggtc caagcctctt gcaatagtcg
    26641 attttccagc ccccataaac cctaataaca ccttagccat gaatcaagct ctccaaatca
    26701 tcaaagaaac taggatagct ggtattgatg gcttctgcac ggtcaagctc cacctctcca
    26761 cctgcaacca atagggctgc gatagctgtc atcatgccga tacggtggtc accaaacgta
    26821 ttgactctag caccgtgaag agctgatttt cctttgataa tcatcccatc tgccgtagga
    26881 gtaatatctg ctcccatact atttaaggcg tctgccacaa cctgaatacg gtctgtttcc
    26941 ttgaccttga gctcctcagc atccttgata actgttacat cttgggcttg ggtcgcaagt
    27001 agggcaataa taggcaattc atcaatcaaa cgtggaatca aagcgccaca aatctctgtt
    27061 cctttcaagt cagaagactc aacaatcaag gttgcagatt tagcgactgg atcgatttca
    27121 gttatttcca attttccacc catggcacga atgacatcaa taataccggt gcgagtttcg
    27181 ttgatcccca cattctgcag cactagacga gaatttggag caatcaaacc tgcgactaac
    27241 caaaaggctg cactggaaat atctcctggt acgaccacct tctgtcctgt caatttttgt
    27301 ggcccttgga ctgtgatttt cttaccgtcc acacttaaat gaccaccaaa ttgttgcaac
    27361 atatcttcag tatgattacg ggtgtactct ttttcgataa taactgactc ccccttagct
    27421 tgtaaggctg caaacatcaa ggctgacttg acttgggcag aggcaattgg caactcataa
    27481 tgaataggtc ttaggttttt cgtccctttt aagcgaaggg gaggcaagtc tcgttcagtt
    27541 tgtcctgaaa tgctgacgcc catttttttc agtggaaggg tcacacggtc cataggacgt
    27601 ttggaaagac tatcatctcc aaacatctct acttcgaaat ctgcaccagc aaggacacct
    27661 gaaatcaggc gaatcgaggt gccagaattt cccatattaa gggcattttg cggcgctttt
    27721 aagccagcca tgcctacacc ttgaatggta ataaccccat ctttatcctc aatttcaaca
    27781 ccaaggtcac gaaaaacctg catggtcgaa agaacgtctt cacctcgcag aatatcataa
    27841 accttggtct caccctcagc caaacttcca aagataatgg aacggtggct gatagacttg
    27901 tcacctggga cgcggatact accatgtaaa tggcgaatgt ttgtttttag tttcatactg
    27961 gacctcatac ttgcaatact tttacctatt ttatcataaa aagccagaaa ttccttaaaa
    28021 attcctgact ttaggatagt tcttttctta tttcagcaat tctgaaactg gttcaaaaac
    28081 aattttttca atgtcagaaa ggtaaatggc caattgttgt tgcttggtaa agaattctga
    28141 caagaggcta tttccttgaa tctgtttacc aaagccttcc atcttagctt ggaaggacgc
    28201 atctggcatt tgacctgtct gtgctagttt ttgaatttcc tcttgaaagg caagatattc
    28261 tgtaaagatt ttgcttgcct cagcatctgc tgcaatcgca tctttagctg ctttaacagc
    28321 cttgtattct ggtaatccgc gtagaccgcg actgagttcg tttgcactat cgtaaatatt
    28381 tgacatgttc ttctccttat ttgatgacga ctgtatagtc ggtattttct gttatgagat
    28441 gctcagctct ttccaagtct tgagcatttt taaatgaaat ttgtaggatt ccgtgaatat
    28501 cctcacgatt ttcctcgttg atgtggatgt taaccaagga agttccacgt agcagttcca
    28561 aaatccgcag gatgacatct tcttcatcag gaacgtcaac atagaggtcg taagagctat
    28621 ccacaccacc acgcttatgg atttccatgg tctggcgttg ttcacgcgct tggttaaaaa
    28681 agttccaaat ttgctcttca tctcccttac taatggcctg accaatcact tccaaacgtt
    28741 ccttgaaatc ctcaattcta tccagaatgg tctcgctatt ggacaagaga atggaggtcc
    28801 acattcctgg ctcgctttcc gcaattcggg tcatatctcg aaaaccacct gccgcaaagc
    28861 gccttgccat ctcatgctct tgagcataga ccgcagtctg ctccatgaga ctagaagcca
    28921 aaatatgagg gaaatggcta atctgagaag tgacacgatc atgctccttg gcatcaatct
    28981 cgataaaacg agcatgaaga cctgaaagca gatccttcat ttccttaagc gtgtcctgac
    29041 ttgtcaggct tgaaggtgta aagatataat aggcattttc aaaaagattg acatctgccg
    29101 aagcagcccc tgtcttgtga ctaccagcca tgggatgggc cccgacaaag cgaacagact
    29161 tgccagccaa atactgctcc gccgcatcca caatggttga cttggtcgaa ccagcatctg
    29221 aaataataac gccttctcgc aaatccaaat tggccaactc cttaatgaaa gcaatagttt
    29281 gtttgattgg caagctgagg ataatgacat ctgccaaagg agcaaaacta gcaaaatcat
    29341 ccgttgcacg gtcaatcata ccttctttca aggcgatatc tctcgaagct tgactacgat
    29401 tataacctaa aatttcataa tctggatgat cgcgtttgat accaagtgcc atagaggctc
    29461 caatcaaccc aagacctgcg atatagattg tttttgccat aggaactcct taatagttct
    29521 ttgtatagtc tcggtgtttg gctaccgctt cttttagttc ctcaagatta tctgatgaga
    29581 atttttcgag gatttcttgc gccagaaccg ttgctacaac tgcttccatg accattcctg
    29641 cagctggaag agcagtcgga tcacttctct ccacggttgc cttgtaaggt tcgtgggttt
    29701 cgatatccac actcataaga ggtttataaa gagtaggaat gggtttcatg accccacgaa
    29761 caacgatggg ttgcccatta gtcataccac cttcaaaacc acctagatta ttggtacggc
    29821 gagtataacc gtcttcttta gaccagagaa tttcatccat aacttggctg cctttacgat
    29881 aaccagcctc aaagccaaga ccaaattcca cccctttaaa ggcattgata gagacaacag
    29941 cttgagccaa tcttgcatcc aattttctat cccattggac ataggaacca agaccaactg
    30001 gaacgcctcc gacgactgtc tccacaaccc caccgatggt atcaccatca cgtttgattt
    30061 ggtcaatata gtccttgatt tcctgttctc gttcttggtt gacaatagaa acttcagact
    30121 gggcagctct ttgcttaatt tcagcgactg tcagattttc aggaacatct atttccttac
    30181 caccaaagac cacgacatgg ttggcaatct ccatatccag ctcagccaag aggcgtttgg
    30241 ctactgcacc aactgccacc cgcatggtgg tttcacgagc tgatgaacgc tccaaagaat
    30301 ttcgcaaatc atcaaaacgg tacttaatcc ccccaaccaa atcggcatga cctgggcgag
    30361 gatgagtaat tttccgcttg cttttaaggc ggtcttcaat gtcctccgca gacatgatgt
    30421 ccagccattt ctggtggtcc ttattgatga catccatagt aataggcgcc cctgtcgtct
    30481 tcccgtggcg aacgcccgaa gtaaagacaa cctggtcact ctcaatcttc atacgaccac
    30541 cacgaccgta gccaccctga cggcgtctaa ggtcctcatt gatatcctca gctgtcaatg
    30601 gaagtccagc tgggattccc tcaataatag ctgttagacg ggggccgtgt gattctcctg
    30661 cagttaaata tctcatacac tctccttatt ttaccaagta gtctttcatc tcttccagag
    30721 aaactgggtg aatgatcgct gaaccaagct ctggcaccaa gaccaatttc aaggtgttac
    30781 cacgcgcttt cttgtcatga gtaagagcct gataaagctt gtcaacttcc caattttcat
    30841 agtcaacagg caagccgaat ttctgacaca tctctgtgat agattgggta atgccagctg
    30901 gcatgaggcc tttttcctca gcaaccttgg aaatctgtac cattcccatg gcaacagcct
    30961 ctccatgcat gaccttgcca taaccggcag tcgcttcgat ggcatggcca atagtgtggc
    31021 caaaattgag gtaaagacga ataccattgt ccaactcatc ttcaaccacc atcttgcgct
    31081 tcacctgaca agaatgttca atcaaggtct ctgcatgttc caaaatactc tcaacagaac
    31141 cattcagtcc cgtcaagaga gcccacagtt ctggatcctc aatcaagcca tacttgataa
    31201 cttcacccat cccttcaatc aactctcttt ttccgagggt ttcaagaaca agtggatcaa
    31261 tcagaacccc atctggttgg gcaaaggtcc ccaccatatt tttagcaaat ggtgtgttaa
    31321 cgcctgtctt tccaccgata gaagaatcaa cctgagctgt caaactagtc ggaatctgaa
    31381 caaagtgaat accccgcata taggtagagg ctacaaagcc agccaggtcc ccaacaacgc
    31441 caccaccaag agcaacgatt ccatcgctac gagtcagacc ttgcttgact agaaattcat
    31501 agactttctg aacagtagtt aaattctttc tttcttcacc ttctaagaaa tcaaaaacag
    31561 ctacctgaaa accagcatct tctaggctga gcttgacctt ctctgcatag agagaggcta
    31621 catggttatc tgtcacaatg actacctttt gcggttgcca gagttctcgc aaccactgac
    31681 cagcctgggc catacaacct ttttcaatct gaatatcata aggatgatga ggaatatcga
    31741 ttctgatttt cataggagag tctccctttc tttattggta tttttctgtt aaagactgcc
    31801 aaatctcttc tgtcggcatt tccttgcctg tccacagttg aaaagcttct gcagcttgat
    31861 agagtaacat tcccagacca ttgactgctg gattgccctg acttctagcc catttcaaaa
    31921 acggtgtttc aaagggttgg tatatgatat ctgcaactaa gagagtttct ggtaagacta
    31981 tgttttcagg aacaggagag gattggccat ccatgcccac actggtggca ttaactagca
    32041 aatccgactc ggcaatcctt gcttgcagtt cagaaacata ttctaaagca cacaaatcca
    32101 ctttaaagcc tgtctgctcc tgtaacttgt ctaggtaagg tcttgttttt tccatagaaa
    32161 cggaacgaac aaagaccgaa atctgactga cgccatccaa aatagcctgt gccaagattg
    32221 atttagccgc accacctgca cccagcaggg tcatcttttt acctgaaatt gtaaaagaag
    32281 gcaagcactt aaaaaatccc ttgccatctg tattatatcc aattaaattg ccattctcat
    32341 tgacaaccgt attaaccgca ccaatcaagc gcgcttcatc gctcagctta tccaaataag
    32401 gaatcacctg ctccttatag ggcatggaca gattgatgcc aaacatctgg tagcgacgaa
    32461 tattggccac tgtttctacc aagtcactcg cttcaatctc ccaagccaca taagcaccgt
    32521 tggtatctgt cgcctcaaag gctctattgt ggatgaaggg agaaatagaa tgcttaatag
    32581 gattggcaac aactgcagct aaacgtgtat agccatcaag cttcatccaa aatctccctg
    32641 atttttttca tgctagctag agaaatctgc ccaggggcac taacctcatc cagactggca
    32701 aaagaccaac tcgaaccagt cacatccgca gtgatacgag agaccttgcc caccttaccc
    32761 atagaaatgg tcacatattc ctgttcagga ttgagggttt taaagcctcg tgtatagttc
    32821 atcaagtcta agacatcctg ctccgtgtga gccatcaccg caaccttaac aagttttgga
    32881 tttaggatcg tcaactctga caagatttcc atcatgttct caggtgtttc ttggaaatta
    32941 tggtaactca aaacaagatt tgggaagtcc agcatttcct caaaaacatc cttgtagcta
    33001 tagtactcaa aatcaatata gtctggttga tagagttgcg caacttcctt gattagatgg
    33061 atatactctt ctggagaaag gtcgatttct ccaccttcgg agcgagttcg tagcgtgaaa
    33121 accaactcac ggcctgcgaa tttttcaaaa atggctggag ctacctgcaa aatcgcttct
    33181 ttaggcagat agtcggcacg ccattcaatg atgtcggcat ccagatacct cgtggcatcc
    33241 agagcctgag cctcctctaa acttcttggc attactgaaa cgattaattt catttactaa
    33301 ccttcatact aatcaccttg aggtaattac tactttcatc ttttttatta taggcaaaat
    33361 ctgctggaag accatatttg tttaaaatct ggtaacttct tcctgcaaaa cctttatcaa
    33421 tttgttctgt aaatttctgg cgggaaacat tggcagcatt ggtactggca atgataatcc
    33481 ctcccggatt taaaatctca agactctggg aaatcaactt gtgataatcc ttggccacag
    33541 agaaagtttg ttttttattc cgagcaaagc taggcggatc taggacaatc acatcgtagg
    33601 tcaagtcttt gcgtttggca tatttgaaat actcaaagac atccatgact ataaaacgat
    33661 gctcgtctgt gctgagccca tttgcctgaa aatgcgcttg agacaattct cgtgaacgtt
    33721 tggctagatc aacagaagtt gtctggctag ctcctcccat ggccgcagct actgaaaaag
    33781 ccgctgtgta ggaaaacata ttgagcaagg atttacccat agtcaagccg tcaactaaac
    33841 taccgcgaac ctcatgctgg tctaggaaaa ttcctgtcat caagccatca ttcataaaga
    33901 cttgatacag gacaccattt tctaaaacag tgaaaaagtc aggtgcttct tgaccataaa
    33961 catgggcaga ttcatagtca aaacccttaa agcggatttt ctcataagcc cctaaaacct
    34021 cagggaaaac ctgtctaaag gcttctgata tagtctgacg aatctgataa acataagagt
    34081 tataccaaga aaagacggcg tagtcgccat aaaggtccac tgtcagaccc ccaaagccat
    34141 ctccctcttg attaaagaga cgaaaggcag ttgtcaaatc atcttgatag taggcgtttc
    34201 tcttttcttt ggcttttcta aacaacgttt caaagaaagt ttgattgaag gtcaccttgt
    34261 ctttgctgac aaaccagccc aagcccttgt tttgctgaga aaggtaggca gtcccaagaa
    34321 agtttccttc ctgaccctgc acctctactt cctgatcctt aagattgaca ttctcaagat
    34381 cactggcttc tagtaaaact agccccttag caagcttctt ttcaaccctt ttgctgactc
    34441 ttattctatt cataactacc attatatcaa acttttagac aattctcaaa aaagaaacta
    34501 cccttgcttt tttactcttc ttttaaaaaa tggtatacta gacttcctgc aaaactagga
    34561 agtaaatgtg taagaatcac aataaaaaat gctcttccgt cttggaggag cattttttat
    34621 tatcaacgaa aatcaaatag caaactatga aactagcctc aggttaactg tgagattata
    34681 ggtagagagg ttgtatcagc aatatgtgtc tgtcaaattt agtgacaaag gtagtagaag
    34741 aaagatgaag aaataaatca gcttcagtag atatctggaa aatttgattt tatagagaag
    34801 ccttttgtta caaactcaat atactatcaa taaataatat tatagaagca acaataatta
    34861 taatttcacc tatttgcatc attctatttc gaactctaaa tatatgttct atcaaaaata
    34921 cttggatcac acacattata ggaattaacg tttttgaaat tgaaaaatat cccaataaat
    34981 aaactataaa caacaaaaat agaactatgt tatatttctt attcaaaaca ttcctcccta
    35041 tatttttgat taccaatctt aatcatttac aactacattc taacaaacta taaaagcgtt
    35101 tgtcgaattg aatttatcaa gcaagcgacc aaccagctca tcttttttct atttctgcca
    35161 atatgcgtga caggtaataa tgatagccaa aaatagcaag agcaagcagg aggataagag
    35221 ctcctactcc caagctgatg gcaaggatag tggagagaga ctgaaccaag aatatgctcc
    35281 caattacaag ggccatcagg attgcactat aaataaacaa taaaactatg gcgactatgc
    35341 catttgaacg attcaccagg tccgtaatgc tactccaatt gattgacaga tttttaacgt
    35401 ccttaaagta atggtggcaa gaaaggatga cactggcaag gatccatgcc ataataaggt
    35461 aaatcatcga aatgatgggc aagcctagat atagagaaag accaagtaaa gtcagaattg
    35521 gtaaaaagga ctggacggca tatataatcc aaaatttcac tttcacataa cgagcaaagt
    35581 caaagggtaa actcttcaga aaatcaacat tttccctctc caaggacaag gcaattgaat
    35641 gcaggctggt gatattgtta ttgacaactg ctataaagag agctataaaa aacaagggta
    35701 accagtatgg aggatgaatg tctggaacta tctgagaatc tcggattttg gaaatcagac
    35761 cgatcatcat gagataagga aggaaagcac ttgtaaaaag cactgtaacc acgccagtac
    35821 cctgtcccaa gagggtgagg tggtagcgta aaaccatgcg gaaaaatccc tttttagtgg
    35881 ttgaaattct ctccttgctg cgacgttctt ttttgacctt ctcctcacta ttaagcagga
    35941 tcacgtcata aaaacgagga aggaccttct ttttggtcag ataaagcagg aagagagtta
    36001 gtcctatcca agcgagcaga cccactaagg cttctgtcga aaaaggctcc actgctattt
    36061 tgtaaaagat atgaagagga taaaggagaa atggaatgtc tctaactttg tcaacaatac
    36121 ttccaaaagt cgactgtaga aagaagacaa atattaaagg tatgagaact cctatcccaa
    36181 tcatcacatt cgaaaaaata gactgatact ttctgaaggc cgtagtttga gccaagaaat
    36241 gcactgccac taccatcact agagccacag agacaaataa taaggtcaag gacagtagca
    36301 tcaaaggcaa acccagccaa agagaaggag ctagactaat atagagggct agaaaataag
    36361 ctaggattgg tacaattcca gttagagctg gcaaaaggac agacagtcct ttagcaatta
    36421 taatctctga ttctttaaag gcatagggcc tataggaggc caggtcctta ctctcataaa
    36481 agacattgta aaatgcagtt aaagaagttg aaaaggcaat cactagtaaa atagcaacca
    36541 caaaactaaa ataaacaggc atttcctcaa aaggaaaatg aatggctata gtactaaaaa
    36601 agatgagcat caagagactg gaaaaaatgt aagaacttag gactctagcg gaaacattta
    36661 ctttttttcc agtattttta gcttgcttct ttcgtaggtt agccagatta gcttcttgag
    36721 atgaatagag gatattgata tcaactaatt ttttaatgac cttgagacgc atctgaaacc
    36781 tcctcttttc taccagcaag gctaaggtag atactttcca aagactggtc tgggttgtct
    36841 cttctcaagt cctctacctt accacaataa atcaaatgcc cctttttcaa aatagcaatc
    36901 cgatcacaga cttgctcagc tacctctagg acatgagttg aaaacaaaac tgtcttacct
    36961 ttttgcgcat gctccttcat catttgcttc aaatcaaagg cagcctgggg atccaaacca
    37021 gtcaagggtt cgtccaagac ccaaatatca agatcagaca agagtgcccc gatgacaaaa
    37081 actttctgac gcattccatg agaaagggtt tcaataacct gataacgatt ttcagcaaaa
    37141 tcaaaaacgt tcaataacct agctaaacta gcttccaagt cagagctgct caaatcatag
    37201 gatgaagcaa tcaattccca aaattcattg gccgttaaac gtaaaaataa gtcaggcgag
    37261 tctgctacgt agccaatctt tcgtttgatc gccaagcgat tttccgataa atcctgacca
    37321 tctaccaaaa tacgaccact gctgggtgaa atgatactga ctagggattt tatggtggtc
    37381 gattttccag ccccattatg accaatcaag cccataatct ctccattttc aatctgcaaa
    37441 ttgagattac tcaaggcctc tttatcacca tacaacttac taacattttg aaattcaatc
    37501 atgggacaac tcctatcttt atctgtatta tacatcgcta tactagcact ttgatacaaa
    37561 aaaatcaata ctttatttta agtagttaaa atagtttcct tctatcttac gcaaacgttt
    37621 gcgctaatag atactttatg atagaataaa gaacaagatt gacaagtaag aggaaacatc
    37681 atgcaaaatc aaacactcat gcaatacttt gaatggtatc tgccccacga cggtcaacac
    37741 tggacgcgtc tggctgaaaa tgctccacac ctagctcatc tggggatcag tcacgtctgg
    37801 atgccaccag cttttaaggc aaccaatgaa aaagatgtag gttatggggt ctatgactta
    37861 tttgacctag gagagttcaa ccaaaaaggg actgtccgca ccaagtatgg tttcaaagaa
    37921 gactatcttc aagccattca agcccttaaa gcgcagggaa ttcaaccaat agccgatgta
    37981 gttctcaacc acaaggctgc tgccgatcac agggaagcct ttcaggttat tgaagtggat
    38041 cctgtagacc gtacagttga acttggagaa cccttcacca tcaatggctg gactagtttt
    38101 accttcgatg gtcgccaaga tacctataat ggcttccact ggcattggta ccacttcacc
    38161 ggtacagact acgatgccaa acgcagtaaa tctgggattt atctgatcca aggggacaac
    38221 aagggctggg ctaacgagga attggtcgat aacgaaaacg gaaactacga ctacctcatg
    38281 tatgccgacc tagactttaa acatcctgaa gtcatccaaa acatctatga ctgggctgat
    38341 tggttcatgg aaacgactgg tgtagctggt ttccgtttgg atgccgttaa gcatattgac
    38401 tctttcttta tgcgcaactt catccgcgat atgaaggaaa aatacggtga cgatttctat
    38461 gtttttggtg aattttggaa cccagacaag gaagccaatc tggactatct cgaaaaaacg
    38521 gaagaacact ttgaccttgt cgatgttcgt ctccaccaga atctctttga agccagtcaa
    38581 gctggcgcaa actatgacct tcgtggcatt tttacagata gcctggttga actcaagcct
    38641 gacaaggctg tgacttttgt cgacaaccac gatacccaac gaggacaagc ccttgagtct
    38701 accgttgaag aatggttcaa gccagcagcc tatgccctca ttttgttacg ccaagacggc
    38761 cttccatgtg tcttttacgg agactactat gggatttcag gccagtatgc tcaagaagat
    38821 ttcaaagaaa tccttgaccg cctcctagcc atccgaaaag acttggccta tggagaacaa
    38881 aatgactact ttgaccatgc taactgtatc ggttgggtac gttcaggtgc tgaaaatcaa
    38941 tccccaatcg cagtccttat ctcaaatgac caagaaaaca gcaagtcaat gtttgtcggt
    39001 caagaatgga ctaatcaaac ctttgtagat ttacttggta accaccaagg tcaagttaca
    39061 attgatgagg aaggttatgg acaattccct gtctcagcta gatccgtaag tgtctgggca
    39121 gtcaatacca tctaatagct cataataacc aagctaggtc caagcggatt tggctttttt
    39181 gtattcacaa aaagacctac ccaaatggat agatctttac ttgattacaa tttacctgct
    39241 actgcatcca acaattcttg gatcttagct tggttgcttc ctcctgccat ggccatgtct
    39301 ggtttaccac caccacgtcc atcgatgatt ggtgctaatt ctttgacaag gtttcctgca
    39361 tgaaggtctt ttgtcttgct tgctacaagg acattgactt tgtcaccgat agcggcaact
    39421 aggacaagaa gatcagagta gtctttttgt ttccagttat ctgcaaaagt acgaagggca
    39481 ccggcatcgg atacagacac ttgactagca atgtaacgat gaccgttgac ttccttagca
    39541 tctttgaaga tatcgcctgc ggctgcagct gcggcttttt ctttcaactc agcattttct
    39601 ttttgaagtt gacgaagttg ttcttgaagt ccttctacct tgtgaggtac ttccttgact
    39661 tgaggtgctt tcaaggttgc tgcgacagct ttaagagcat cctcttgttc acgataggct
    39721 tcaaaggctt ccttaccagt cactgccaag atacggcgag ttcctgaacc gattccttct
    39781 tctttgacaa ttttgaagag accaatctca gaagtgttgc caacatgagt accaccacaa
    39841 agttcaatag agtagtcacc gatagtcacg acacgaactt ccttgccgta tttctcacca
    39901 aagagggcca tagctcccat ttctttagca gtgtcaatat ctgtttcaac tgtcttcact
    39961 tcaagtgctt cccaaatttt ctcgttaact tgctgttcaa tcgcacgaag ttcctcagca
    40021 gttactgctt ggaagtgggt aaagtcaaag cgaaggaatt caacttcgtt aagagatcct
    40081 gcctgtgttg cgtggtttcc aaggatattg tgaagggcag cgtgaagcaa atgagtcgca
    40141 gtgtggtttt tcatgacacg gtgacggcga ttgctatcaa ttgccaaggt atattcttgg
    40201 ttcaaggcaa gcggtgcaag gacttcaact gtatgaaggg cttgaccatt tggggctttc
    40261 tgaacattgg tcacagtagc cacaatctta cctgactcat ccaagatttg tccgtagtca
    40321 gctacctgtc cacccatttc agcataaaat gacgtttccg caaagataag agaggcagtt
    40381 ccttctgaaa cagctcctac ttctgcattg tcagcaacga tagctaccaa tttagaagac
    40441 aattggctag tattgtagtt gaagacactt tctacagtga tgttttgaag agtttcattt
    40501 tgcataccca ttgagccacc cttgacagct gacgcacgcg cgcgttcttg ctgttctttc
    40561 atggctgctt caaaaccttc acggtctaca gtcataccag cttcttcagc aatttcttca
    40621 gtcaattcaa ctgggaatcc gtatgtatca tagagtttaa agacatcttg accagcaatg
    40681 acagattgac ctttttcttt caagtctgcc acaatgcctt gggcaaagtg ttgacctgag
    40741 tgaagggtac gggcaaatga ttcttcttcg ctcttaacga ttttctcaat aaagtcacgt
    40801 ttctcaagca cttctgggta gtagctttcc atgatttttc caacagttgg aacaagtttg
    40861 taaaggaaag gctcgttgat acccaatttt tgaccatgca tagaagcacg acggagaaga
    40921 cgacgaagaa cataaccacg accttcattt cctggaaggg caccatcacc gatagcaaat
    40981 gaaagagaac gaatgtggtc tgcgataacc ttgaagctca tgttgtcgcc atcttggtca
    41041 taaaccttac cagacaattt ctcgacttca cggataatcg gcatgaagag gtccgtttca
    41101 aagttggtct tagccccttg gataacagcc accaaacgct ccaaaccagc gcccgtatca
    41161 atgttcttat gtggcaattc cttgtattcg ctacgaggaa cagcagggtc tgcgttaaat
    41221 tgtgacaaaa cgatgttcca gatttcaata taacggtcgt tttcaatatc ttctgcaagc
    41281 aggcgaagac cgatattttc tgggtcaaag gcttccccac ggtcaaagaa gatttctgta
    41341 tctggtccag aaggtcccgc accgatttcc cagaagttgt cctcaattgg aatcaagtga
    41401 cttgaatcca ctcccacttc aatccagcgg ttgtaagaat ctttatcgtc tggatagtag
    41461 gtcatgtaaa gtttttcagc agggaaatca aaccattcag ggcttgtcaa aagctcataa
    41521 gcccaagtga tagcttcgtc acggaagtaa tccccgatag agaagttccc cagcatttca
    41581 aacatggtat ggtgacgcgc agtcttccct acgttttcga tgtcgttggt acggatagcc
    41641 ttttgggcat tggtaatacg tggattttca gggataatgg tcccgtcaaa gtatttctta
    41701 agggttgcta ccccagagtt gatccacaaa agagttgggt catttacagg aaccaaactt
    41761 actgatggtt ctactgagtg agctttggtc gcccagaaat caagccacat ttggcgtact
    41821 tgtgcactag atagttgttt catattgtct ccttatttac ttgtttaatg tgattggctt
    41881 tccagcattt ccacatagtc aatcgcgaca cagagggaaa tgactaggtc tgcataagcg
    41941 tcctcaagaa ccgttacggt ataggtagag gtcagatgga agagttcctt cttaatttcc
    42001 gcaatcagct gatcgcgatc atccagcaat ttgaaattca aatcccagat attgccctcg
    42061 atacgaagac ctagattatc aaactcatac ttatctcgcc agaaggtcaa cttcttacga
    42121 atgacaaaac tcgagccatc ccgaagctga atctcaaaac gaggaagcaa ggtcaagatt
    42181 tctttactaa tctcactgac ttgttcacca gccgcatcat agatggtaaa ggttttagga
    42241 atcttaaaaa atgatccctc cacctgatag gcaatttctc ccctgtcatc cttgatagcg
    42301 aagcgttcgc ctccaagacg aaacttttgt ttgacaagaa atgttttcat caacacctcc
    42361 aaaaatcaaa agacaagctc atatcacgaa gggcgaaaaa ccgcggtacc accttcattc
    42421 aatgaacttg tcattctctt gttcttatgc aattgtatga ttgagtagca tgacttccta
    42481 gcttagatgg ctcgcagcac cgccatttct ctggactaag acaagtgaaa atcaattctc
    42541 aactttctta ttataacgtt tttttaagct tgcgtcaact ggaaatgatc tccgttgaat
    42601 tagaccaatt ccctacatct ctgattactt tttcaggata tattttttct tactgccgtt
    42661 tttcttttta tcccaaattt tcatattact aaacacagct actagaatat ttccaaatat
    42721 aaaggtgcct atcacccaat atatggactc agttgttagg tattgtcgat ccaagccatc
    42781 ctttaaatgg gatagtataa cagtttggtt aacaatcata aaggttggcc agaaactttt
    42841 tttgaaaaaa gtagacattt tcattatttg ttgccgcttt ctgtaaggtt aatactcaat
    42901 aaaaatcaaa aagcaaacta ggaagctagc ctcaagctgt acttgagtac ggcaaggcaa
    42961 cgctgacgtg gtttgaagaa tataggctta gtatactact aggcaagcaa ataagcaact
    43021 agaatagaaa aagatagggt tctaaaaact gacttctatt ccttaaaaac gaaccagctt
    43081 gactgattcg tcttcttacg tttatctcct acttccgata cattttaaac tgtaggaaga
    43141 ggtcgctata tttccctgtc catttatggt caaatttctc ataaacttct aggtgtttca
    43201 tggtttcaac atctggatag aaggccttat cttcctttgt ttcctctggg agcaattcct
    43261 tcgctggtag gtttggtgtt gaatagccga catactccgc attttggaaa gcgttttcag
    43321 gtttcaacat aaagttgata aaggcatagg ctgagtcttg gtttttaact gttttgggaa
    43381 tgaccatatt gtcaaaccaa agattgctgg cctctgtcgg taccacataa cgtagatttt
    43441 catttttttc taacatttgg ctggcttcac cagagaaggt cacgccgatt gcaacattat
    43501 tctgaatcat gtagcccttc atctcgtccg caacgatagc cttgatattt ggagtcagtt
    43561 tgtagagctt atccactgtc tcttccaact gctgcggatc cttggagttg aggctgtagc
    43621 cgagggaatt gagtcctagt cccagcacct cacgcgcccc atcaaaaagc atgatagaat
    43681 tcttatactc cagcttccaa aggtcatccc aatgctcagg cgcttcatct accatggttt
    43741 cgttgtagac aattcctaag gttccccaga agtaagggat ggagaattta ttacctgggt
    43801 caaaggactg gttgagaaac tctggtccga tattttcgat tccttcaatt tttgaataat
    43861 caagcggaac caagaggtct tcgtccttca tcttgttaat catgtattca cttggaatgg
    43921 caatatcgta ggtcgttcca ccctgcttta tcttagtgta catggcttcg ttggagtcaa
    43981 aagtctcgta ctgaacttga attcctgttt cttctgtaaa ctgagtcaag agttcaggat
    44041 cgatatagtc tccccagtta tagataacca atttttgact atctcgacta ttgattttac
    44101 tatctaaatg agtcgcaatt ccccacaaga caaggataat cgctgcaatt cctgctaaaa
    44161 atgaatagat ttttttcatg cttgctcctc cttctcacga gagataaagt aataacctac
    44221 aactaggata atactaaaga gaaagactag agcagacagg gcattgattt ctaaggaaat
    44281 ccccttgcga gcacgagagt aaatctcgac tgatagggtt gaaaagccat ttcctgttac
    44341 aaagaaggtc acggcaaagt catctaacga ataggtgaag gccatgaaat aaccagtaat
    44401 gatagacgga gtcaggtaag gaagcatgat ttccttgaac atctgaaatt gactagctcc
    44461 caagtcatag gccgcatgaa tcatgtcgcc attcatttcc ttgagtcgag gcaagaccat
    44521 caagaccacg ataggaatgg agaaggccac gtgactagat agaacggtca aaaagccaag
    44581 tgaaaacttg agttgggtaa agagaatcaa gaagctagca ccaatcataa cgtcaggcgc
    44641 aaccatgagg atattattga gtgatagaaa ggcttcttgg tatttcttac gagactggta
    44701 gatgtaaatg gcaccaaaag tcccgataat ggtcgctatc aaggctgata ggaaggccaa
    44761 gaaaaatgtc tgagccaaaa tcagcatgag tctcccatct ccaaacatgg tttcaaagtg
    44821 agtccagcta aaacctgtaa agctattcat atcatcacca gcattaaagg catagccaat
    44881 caagtaaaag ataggcaggt agaggaccag aaagaccagt cccagataaa ggttggcaaa
    44941 ttttttcatc gttctctcct ttccttagtc acccacatgg tgatgaacat ggtcaggatg
    45001 agaatcacac cgatggttga acccatacca tagttgtcat tggttagaaa attctgctca
    45061 atagccgtcc ccaaggtgat aacgcggttc ccaccaatca aacgggtcag catgaagaga
    45121 ctcaaacttg ggataaagac cgactgaacc ccacttcgca caccgttcat agatagaggg
    45181 aagatgacat gacggaaggt ctcccactta gtggcaccaa ggtcataact agcattgatg
    45241 agattattat ccatatcgtc taagacattg aaaatcggca aaatcataaa ggggagctcg
    45301 atgtagcttg cgacaaagat aaaggaaaaa tcggtaaaaa gcaactgttg tgaaccaatt
    45361 ccgataaatt ccaagaattg gttaatagag ccattttgac caaaaatccc gataaaagca
    45421 taggctttaa ggagcaaatt gagccaggta ggaaggataa tcagcatgag ccagagttga
    45481 cggtgcttga gacgggtcaa aaagagggct gttggatagc tgataagcaa ggtcacaaag
    45541 gtcacaatcc ctgcataaag cactgagttg aaactcattt tgaggtaggt caagttttgt
    45601 gacgcaaagt aagatttata attttctaaa ctaaactggc cttcaatgtt gaaaaaggat
    45661 tgtccgaaaa tcaagaccaa gggtgccaat acaaagaggg caatccaaag catgtagggc
    45721 actacaaaga gtttagagct tgttttcttc atctctttcc tcctcgatcg cattgatcag
    45781 acctgcttct tgctcttcga tttccacgta ttcttcgata cgagcatcga actcttcttc
    45841 ggtttcattg agacgcatga tgtggatgtc ttctgattca aagtccagac cgatttcctc
    45901 acccacgatg gccttacggg ttgagtggat catccattca tttccaagtt cgtcataggc
    45961 gataatttca taatgaactc cacggaagag ctgggtgtcg accttaactt ggagtttgcc
    46021 ttcttcagga agggtaatgc gcaagtcctc tggacgaata acgacctcaa caggttcatt
    46081 tggcttcatc ccaccatcaa ccgcttcaaa gcgtttgccg ttaaattcga ccaagtagtc
    46141 ctcaatcatg gtacctggca agatgtttga ctccccgata aaggtggcaa caaagtggtt
    46201 gattggctca tcgtagatgt ccacaggggt tccagactgg acaatctcgc catcattcat
    46261 aacgaaaatc cagtcactca tggcaagagc ttcttcctga tcgtgagtga caaagacaaa
    46321 ggtaatgccc aatcgttgtt gtaattcacg caattcgtac tgcatgtctg ttctcaattt
    46381 caagtccagc gctgataaag gctcgtccaa caagaccaca cggggttggt tgatgatagc
    46441 acgggcgatg gccacacgct gacgttgtcc tccagaaagt ttgcggatgg aacgtttttc
    46501 ataaccttcc aactgaacca tcttgagaac ttccgctaca cgctgctcga tttctttctt
    46561 atcaatttta cgcaagcgaa gtggaaaggc aacattttca aacacattca tatgtgggaa
    46621 caaggcatag gattggaaga cggtatgtac gtcgcgcttg ttggttggaa tatcattgat
    46681 acgaacaccg tctagcatga tatctcctgt cgtcgcatcc agtaaacctg caataatgtt
    46741 taggatagtt gatttccccg aaccagatgc acctagaagg gtgtagaatt tcccttcttc
    46801 caactcaaag ttgatgtctt tgagaacctt ggtgttgctg tcttcaaaaa ctttagagac
    46861 gtttttgaat tcgataattg gttttttcaa ttggcataaa ttccttcttt ttcatagatt
    46921 aaccgatcgg ggctctgtca ggtccccact acctcttgca gggagtaaaa ccacctgcat
    46981 acatcttcgc taccgatagg ctttcacccc ctttccatga catagcagca gcttttcaaa
    47041 tacagcttcc tacttgcttt cacccaagat ccggacttct ctttcaagcg taatacctga
    47101 gtgttccttg actttttcga taaccgattg gatcaagtcc tcgtagtctt tggccgttcc
    47161 atctgcgaca ttgatcataa atcctgcatg cttttctgac acttctacgc caccgatacg
    47221 atagcctttc aagccagctt ctgaaattaa ctgacctgca aaatgcccga ctggacgctt
    47281 aaagaccgag ccacaagatg ggtattccaa aggttgcttg agttcacgta ggtgcgtcaa
    47341 gcggtccatt tcctgcttga taacctgatg ggttcctggg gctagggcaa atttaactga
    47401 caagacaact gcaccagact cctgaatagc tgaatggcgg taaccaaaag ccaagtcttt
    47461 agcagacagg gtttcgattt ctccatcctt ggtcaagacc ttacaagact gcaatatgtg
    47521 agcaatctcg ccaccatagg cacccgcatt cataaagaca gcaccgccaa cgcttcctgg
    47581 aataccacaa gcaaactcaa agccagtcaa actatgacgg agggcaatgc gagttgtttc
    47641 aatcaagtta gccccagctt ctgcttcaat ggtatagcca tcaacagaaa cgttattgag
    47701 cttgtcacac aagatgacaa atccacgaat cccaccatca cgaacgatga tattgcttgc
    47761 attgccaaga accatccaag ggatattttc ttggttggca aatttcacaa cgcgagccaa
    47821 ctcaaaacga tttcgtggaa agaccaaata atcagcctct ccacctactt ttgtataact
    47881 atagctatgc aagggttcct taaaacggat atcaattcct tctaagattt caagcatttt
    47941 ttctcttaca gacatgtcac tcttcctttt acaaaattca ttccattata ccatttttag
    48001 agacatttga cgaccataaa aataccttgt ttggattttg cataagaaaa agaggttccc
    48061 ccctttttat gattttttac aaaagatttc cttggttcca taggcaacca gaacgagctc
    48121 cagtgctaga atcacttcaa ccaagactgg atttgtcaac cagcctactt ggaaaagaga
    48181 tggtgccaga tcaaagaagg catgcaagcc ataggctgct aggagataaa tccatttctt
    48241 ctggcgaaca gcttggtaaa cccaaactgt caaaagtaat tggaaaccaa gcgccaagat
    48301 tcgctcaaaa ccaagcaaat aaatctgcca gaccgaaagt gactgaatgg tttttaacat
    48361 attttcagac agtaattgca taacctgtgg attctgagtt tgaactgccg aaagaacgat
    48421 gtaaagattg agtaaactag taaggcctag aaaaatcaac tccaagccac catgccctag
    48481 accataggcc aaggcatctg ccttttccaa acttctcttt ttctccaacc atttgaagaa
    48541 aacaagacga gccgtttcct caaaaaatgc tgccatggct aggccataga taatatagat
    48601 aagcggatga tcttgcaaga gggcaatact accgtctttt tgaggatgca aaatcaagat
    48661 atgcaccagt ttttccaaaa tctgcgaaga gacaaagaaa gcgactgcac ccaagcccaa
    48721 gacagctaga ttaatctggt atttcttttt ggcaaaccaa atgcttccta tcagaaaagc
    48781 tagcaacagc aacatggtaa taatgatatg aatggtcatt ttcttctcct attctgcctt
    48841 ttcaatatct tttttcatct cgtcaacatt gaacttagca aacaagtatt gacggtcttg
    48901 gactgggaaa cgttggtcca actggtcaac tgctcccacc tcgataatgc cttccttgat
    48961 gacaaaatcc atgacatgtc caccgaaggt caaatcatct gatatgaagt gcagatggta
    49021 gcctgccaca ctgaccccat ggaaaatctc aggcgtccag aaaccaacaa tagtccccgc
    49081 aacattgtca cgactatatt ccggttgatg ggttgcgata tcagcaaact tggtatcggg
    49141 tgttgactta ggaatcatac gcacatgcat atgtgaaaat tccccccgaa tcttgataga
    49201 gcggaaaaga ttttccccat cataataaga ctcaattcgt tctttcaatt ccttgtctgt
    49261 catctcaaag cgctggcgga aaatgacctc tgcctgatgc ggtaccactg cagcgtaagg
    49321 aataagggca tctggtgaca cttccacaat ttctggctgg tctcctgact ctttggcctg
    49381 ataagccttg ccatccaaga caatcaattc cccatcaatg gaatccaagg ttcccaaacc
    49441 aaggtcacca tgttctagca attctcctac tgtcatagta ccaccataaa ggccagccat
    49501 caaggctcca agagtattgt attgaaataa tttcactggt tcctgcacgt tcttatccat
    49561 tcactttctt gtctgttatt ctataaatct tactcctaag tataccacat ttgcccctag
    49621 atgtgaacga gagaaacgct ctagacattg ccaagaagga aaaaaaaggg tacaatgtaa
    49681 caaaatcaag ggaggtctgg aatgaagaaa caaagcaagt acaaagaggt cgtttcctat
    49741 ctgaaaaatg gtatcgagtc tggacgattt ccgacgggta gtcgcctgcc ttctatccgt
    49801 caactgagcc ttgactttca ctgcagcaag gacaccattc aacgagccct gctggaatta
    49861 cggcacgaac aatacctcta tgccaagcct cagagtggct actatgtatt agaacaaggg
    49921 caacatcaag acctagaaat cgaggttacc gacgaacatg ccagtgccta tgacgatttc
    49981 cgactctgtg tcaatgaaac cttgattggc cgagaaaact acctcttcaa ctactatgac
    50041 aatcaagaag gattagaaga cctaagacaa tccattcaca aactcctctt tgaccaagct
    50101 ctctactgca aggctaacca actagtactg acttctggaa cccaacaagc cttgtttatc
    50161 ctctctcaaa tatcctttcc tagccaagcc aaggaaatct tggtggaaca gccaacctac
    50221 catcggatga atcgcctctt gattgcacag gggctggact atcaaacgat tgaacgaggc
    50281 attgatggga ttgacttgga ggagctggaa ggccacttca aaacaggaaa aattaagttt
    50341 ttctacacca ttcctcgatt tcactatccc ctaggccatt cctattctga gcaggacaaa
    50401 cgagctattc ttgacttagc agccaaatat agtgtttata tcgtcgaaga cgactatctg
    50461 ggggatttgg actctaaaaa gggccagacc ttccactatc tagatacaga ggaacgcgtc
    50521 atttatatca aatccttctc aaccagcctc tttccagcct tgcggataac agcactcatt
    50581 cttccaaata ctatcaaaga agccttcgtg gcctacaaaa atatcctaga ctacgacagc
    50641 aacctcatca tgcaaaaggc cctgtcactc tatattgaca gtcaattgtt tgaaaaaaat
    50701 cgtttggctc gcttgaccaa tcatgaatct taccaaaaac aaatcgagga aaggataact
    50761 aaaacacctt gtccccttcc tcattatccc ctacacgatg gtttattgct agacctgaga
    50821 cagtatccta aaatcgccag tctcaaacac agtcaactgg gcttggactt ctttgaagag
    50881 gcctatttaa gcacctgtcc ttatcaattt gccaaggtgt ccctagacaa tctggaaaat
    50941 gttttaaact atttaaaagc agaattggaa tgacatccaa ctctgctttt tcttattctt
    51001 caacttcagt taaacttgct gctttttcaa gatagctttg gtaagttcct tcatccttaa
    51061 gtttttggat gaccttgtct accacttctt tcaaatcatc actatttttt ctaagagcaa
    51121 cggcattggc gtcgccgtcc ttcatcttca agctgacagt tgcgacagct aagccagcgt
    51181 ttttagcagc ataactaagt gcaacaggct catccatatg aacagcatct atttttccag
    51241 cctgcaattc attgactgct tcacccatat tagttaggga agttaattga gcttttggca
    51301 attgttcctt gaccattgat tctggaacag tccctttttg ggctgcaata ttagcacttt
    51361 ctaggctagt taaatccttg tatttttcca catcagcctt acgaaccaag aaactaatct
    51421 tgttttcata gtatgggatt gaaaaatcaa agacttcttt tctctcgtca gtagcactaa
    51481 ttcctgcaac tgctaggtca gccttaccag tttgaagact ggtcaaaaca ttgtcaaaac
    51541 tcatgcttaa gatttccaac ttaaccccaa gttcatcagc gatagcctga gccatgtcga
    51601 tgtctgcacc gactacctgg ttctttccat caaccaatga ttgaaattca aagggtgcat
    51661 agtcaggact ggttgccaca actaatttcc ctttttgttt gatagcatcc acagcagact
    51721 gagaaccatt agaacctgac tggcaagcta ctaagaagaa acttgcaaga aaattacata
    51781 aaacaaatat ccattttttt gatttcataa ataaacaacc tctctgttaa ttttgtataa
    51841 ttataacgat atccaagtta cttgtcaagt gttttttaaa tttttatctc aaaaatattt
    51901 tttcgttcaa aaaaaggagc catcagttga tttcaagctc ctttttatac agaattaaac
    51961 tattttatag ttcgacaatc ttacctgttt caaagtagac aacccattca cagatatttt
    52021 tagcatagtc accgatacgc tccaagtagg aaataacttg gaaataatca cgacccgtaa
    52081 caatggcttc tggatttttc ttaatctctt cagtcgcaag gtcacggata gtttcaaaat
    52141 agtggttaat ttgctcatcc atggaggcca cccggtatgc gtcgtcaaca gaaccattaa
    52201 gataaagatc aagtgctgct tcaacaacgc ttttaacttc acgtcccatt tttttaattt
    52261 cttcctctac agctggaatg cgctcttccc ccttcatacg gatggttgcc tgggcaatgg
    52321 ctacagcgtg atcccccata cgctccacat ctgatacagc cttaaggaca gtcaagactg
    52381 tacgcaaatc ttgagagact ggttgttgga gtgcgatcat ttcaaatgat ttcttttcca
    52441 gtttcacttc gtattcattt acttctgcat catcttcgat gacctctttt gccaggtcac
    52501 ggtcatgcgt gacaaaagca cgtaccgtac gattgatttg tgagagcact tcttgtccca
    52561 tagcgtagaa ctggttatgt aatttctcta aatcttcttc aaattgagat cgtaacatct
    52621 ttcatctcct tatccaaatt ttcctgtaat atagtcttcc gtttccttgt gttggggatc
    52681 aaggaacatc tgcttggtat cattaaattc aatcaaatct ccatctagga aaaatcctgt
    52741 cttatcagag atacgtgaag cttgctgcat ggaacgggtt accagaagca tggtgtactt
    52801 gtcttttaga ccatacaagg tttcctcaat tttaccagct gaaatcggat ccaaagccga
    52861 agttggctca tccaagagga tgattttagg actagttgcc aagacacggg ccacgcagac
    52921 acgctgctgt tgaccacctg acaatccaat agctgaatca tatagacgat ccttgacctc
    52981 atcccagata gaggcacctt gcaaggcttt ttctacggct tcatccagaa cctgcttatc
    53041 cttaattcca ttgatacgaa gcccgtagac aacattctca tagatagtca tagggaaagg
    53101 attaggttgt tggaaaacca ttccgatttc cttacgtaat tcaaccgtat ctgtacgcgg
    53161 actgtagatg ttgtggccat tgtacaccac ggatccagtt gtggtcacct ctggattgag
    53221 atctcccatg cggttgagag acttgaggag ggttgacttc cctgatccag atggaccaat
    53281 caaggctgta atttccttag gttggaaaga tagggaaaca ctattcaaag ccttcttttt
    53341 attataataa acggacaggt ctgatacctg taaaatcgca tctgtcatac ggtttccttt
    53401 ctaaccaaag tgaccagata catagtcatt ggtggactgt agcttggcat tttggaaaat
    53461 agttgcagtc ttgtcatact caatcaaatc acccaagtaa aagaagcctg tatagtcact
    53521 tgcacgagca gcctgctgca tattatgcgt tacaatgatg atggtaaagt ttttcttgag
    53581 ctcaaacatg gtctcttcta gttgcatggt cgcaatcgga tccaaggctg aggctggctc
    53641 atccattaag aggatatctg gcttaacaga gatggcacga gcgatacaga gacgttgttg
    53701 ctgaccacct gataaggtca aggctgactt gtggagatcg tctttaacct gatcccagag
    53761 ggcagcctga cgaagggagg tttctacgat ttcatctagg acttgcttat ccttaactcc
    53821 agcacgttca tgcgcaaagg taatattacg gtaaattgac ttagcaaatg gattggggcg
    53881 ttgaaaaacc attccaatgt gtttacgcat ttcataaacg ttgatttctg gacggttgac
    53941 atcaattcca cgatagagaa tctgcccagt tactttagca atatcaatag tatcattcat
    54001 gcgattgaga ctgcgtaagt aggtagattt ccccgatccc gacgggccaa tcaaagctgt
    54061 aattttattt ctttcaaatt gcatatcaat ccccttaatg gattcatttt taccatagta
    54121 aacatggaca tccttagtag aaagggctac tttttcttca ggaaaggtaa ggatatgctt
    54181 ctcatcccag ttatatgttg acatggcttc tcctttaggc agcggttaat ttcttgtgta
    54241 gatagcttcc gaacttacga gctccaaagt taaaaatcag gataaagatc aggagcacag
    54301 cggcagaacc tgctgataca attgttccat ctggaatagt gccttcacta ttgactttcc
    54361 agatatggac agccaaggtt tctgcttgac ggaagataga gatggggcta gtcacactga
    54421 ggatattcca gttagaccag tcaagagctg gcgccgattg ccctgctgta tagatcagag
    54481 ctgcagcttc gccaaagata cgaccagatg ccaagacgac acccgttaca atacctggaa
    54541 gcgcttctgg aataacaaca tgaaccactg tctcccagcg agaaatccca agagccagac
    54601 cagcctcacg ttgggtatgg tgaacgtgtt tcaaactatc ttctacatta cgcgtcatct
    54661 gaggcaagtt aaagactgtc aaggccaagg cacctgaaat gattgaaaat ccatactcaa
    54721 actggactac aaagatcaag taaccaaaga gacccaccac cactgatggt aaagaggaca
    54781 agatttcaat acaagtccgc acaaagttgg taacaggacc ttttttagca tattcagcca
    54841 agtaaatccc agctcccata gaaagaggta cagaaataat caaggtaatg accaatagga
    54901 aaaaggaatt gtaaagctga atgccaatcc caccacctgc ttgaaaagca gaagaccttc
    54961 cagtcaagaa agaccaagag atatggggca agccccgaac caagatatag agaatcaagg
    55021 aagccaagat tgtcacaatg atgctagcaa tcgtatagag gacagctgtt gcaagtttat
    55081 ctaatttttt agcgcgcata atttttcttc cctctttctt tcgtaatcaa tttaatcaca
    55141 ctgttaaaaa ctaaactcat caagagcagt accaaggcca gtgaccagag aacattatta
    55201 tttacagttc ccatgacagt gttcccaatt cccatagtta atatagaagt taaagttgca
    55261 gctggtgtgg tcaaggaagt tgggataaca gctgagtttc cgacaaccat ctggatagct
    55321 aaagcctcac caaaggcacg cgccatccca aagaccactg cagtgaaaat accagaacgg
    55381 gccgccttca agattacacg ccagatagtc tgccagcgag tggctcccat agcgaaactg
    55441 gcctcacgat aataacgagg aaccgcacgc aagctatccg ttgtcataaa ggttacggtc
    55501 ggcaaaatca tgacaaagag gacggaaatc cctgacaaaa tcccaaaacc agtcccacca
    55561 aagacactgc gaacaaaggg aacgacgact tgcaagccaa taaatccgta cactactgaa
    55621 ggaatcccaa ccaggagttc aatagctggt tgtaaaatct tcgccccttt tggtgatact
    55681 tcggtcataa aaactgctgc accaatagca aagggtgttg cgataagggc tgagagaatg
    55741 gtaacgataa aggaacccaa aatcatagga agggcaccaa attctttact agaaggattc
    55801 caagttcctc ccaaaagaaa gtcaaagata ttcacaccat tgacaaagaa ggtcgacaag
    55861 cctttttgcg ctacgaaaac caaaatcatg gccacaagga tgactatcaa agaaagacag
    55921 gcaaaggtca aaccttttcc taatttctcc agacgagaat tctttgatgg aagcaacatt
    55981 ttcttagcta attcttcttg attcattatt gtctcccttc caacactgtc acagttccgg
    56041 cagcatcttt ttcaaccttc atttccttaa tcggaatata cttcaatcct ttgacaatcc
    56101 cttcttgggt ctcatccgag agaacaaaat tgagaaattc tgcagctaac tcattgggct
    56161 gccccaatgt atacatatgc tcataagacc acaagggcca attattgcta cttatatttt
    56221 ctggacttaa gtcatagcca ttcaacttca tgcttttgac cgaatcatct atataggtaa
    56281 gagataaata agagatagct cctggacttt ttgatacgat tgattttacc gctccatttg
    56341 aatcctgctc ctgactttgc atggcagact gaccttccat aatgacagta tcaaaggtag
    56401 cacgagagcc agagccggct gcccgattga taacagagat gggtaagtcc ttaccaccaa
    56461 cctctttcca attggttacc tcacctatga agatttgacg aagttgctct gtcgttaggt
    56521 tatcaacatc aacctcctta ttgacaatca gagccaagcc agctaccgcg accttgtggt
    56581 caacaagagc agaagcatca attccgtctt tttcctcagc aaatacatct gagtttccta
    56641 tatcaactgc cccagactga acctgggaca agcctgtacc agaacctccc ccttggacat
    56701 tgaccgtttt tccaacatgg atcgtgccaa attcatctgc cgctacttca accaagggtt
    56761 gcaaggcagt tgagccaaca gccgttatgg attctccacg atcaatccag ctagcacagc
    56821 ctactaaaca agccgtcagc caaaaagcga taagagacag agcaagcttt tttctttttt
    56881 tcactgtttt tctcctcgaa aataattatg aatactgtga attttttaag tagttcttta
    56941 tgagttgacg catgaattct taccaaattt ctgcgcaatt gattatttat ataatatagg
    57001 ctatattact ctttcctaac ctcctttttt catatgtgga taaaatctct tgtctatccc
    57061 ttcccccatt gtcacccatt atagtcattt cgtgtctctt tttccccttt ttaatgcaag
    57121 ggaaattact ctccttagat gataatctaa aagctagaaa ggtatctcaa atctctctac
    57181 tctcccagac tagtttacaa ctaaaaggaa aagattctat tttatgagaa atctagttta
    57241 caagcggtaa gaacgctaat aactaaactt cttgtactct ttgaaaatct cttcaaagca
    57301 gtgttttgag ctatctatgg ctagcttcct agtttgctct ttgattttca tcgagtagta
    57361 aaactacatg tgatggcaat caagatatca agaatcatcc tactaaaaaa atccatactt
    57421 tcactataac atagaataag atatttgact agcattttca tttgaatctg aggccttttg
    57481 gaaaataatt tttcaaaaca tttccagtaa cctttgcaaa gcccaagcca ttgcctttaa
    57541 ccaaaacttg gtaccaacca tttggcagac tttctgccag ctgaacggtt tctccagccg
    57601 catacttgac aaactcttct tggccaattt caaccgactg ttcgacctga ctcggtttca
    57661 aggctaaacc aagagcgaaa ctgggctcaa agcgtttctt cttaaaagta cccagatgca
    57721 gtccattgcg agcaatcttg agcttcccta aatctggcaa aagttctggc aagagataaa
    57781 gctggtctcc aaaaatctgc aagatacccg gtagattgac cttcaaatgg ttttgggcaa
    57841 attcctgcca caaggcaact tgttcacggc tgaggttact cttacttgcc ttaaatttag
    57901 gagctggatt gttaccctta aactgtagat gggcaacaaa ctgaccctct cccttaaact
    57961 gatgagggta catccgagcc gtttctggca ggtcaatacc agctaccatt ccattgatat
    58021 gctctactgg caacaagtca aaatcatact cttccagcaa ccaattgaca atctcttcgt
    58081 tttcctcggg tgcccaggta caggtcgaat aaaccagacg accaccttca gctaacatgg
    58141 tcactgcatc ctccagaatt tctctttgca agctagcaca ttgactcgga taatctaagc
    58201 tccaatagtc catagcatca ggttgcttac gaaacattcc ttcaccagag caaggggcat
    58261 caagaacgat taagtcaaaa tagcctttaa agaccttgac caagcggtcg gcagattcat
    58321 tggtcaccac gacatttgtc gctccaaaac gctccatgtt ttcaaccaaa atcttagccc
    58381 gtttgcttga aatttcattg gaaacaagta gcccctcccc tgctagatag gctgccagtt
    58441 gagttgattt gccccccggt gcagcagcca agtccaagac cttcatacca ggactgggtt
    58501 gggctacttg agccaccatt tgagcagcag gttcttgcga ataaactaaa cctgtagcat
    58561 gctcaggcga tttccctgaa accttcccat agtggcccca aggggtttga gtaatggcat
    58621 cagaaaagga aagttgctct tcttttaagg gattgacccg aaaggccgaa accgcttcct
    58681 cctcaaaaga ggcaagaaaa tctcttgcct catctcctag tatttcttta tatttttcaa
    58741 caaatccttc tggaaatttc atttaagttc ttttcctttc gtaaatatag gactgaattt
    58801 cctcctgcat ctcaagaggc accatcatga ccggctgtct ggtttgaaaa tcaggagctt
    58861 caccaaaaag ggtcacaacc cgatagccca gactttcccc taaaatacta gctgcggcat
    58921 aatcccatgg ttgcagatag gtgagatagg tcaacaaacg ccctgacaaa atcttggcaa
    58981 aactaatggc cgcacttcca tagacacgaa caccaagaac cgctcggctc aaatcagcca
    59041 gcccccattc attggtttcc agcataccac tattccctgc aatgagaaaa tctccaagtg
    59101 gtttagtttt aaaagaagct aggggcctat catttagaca aactggaaat tccccaccac
    59161 cgtggtaaca atcccctttg accacatcat aaatcagacc aaactgtccc tgaccatttt
    59221 caaaataagc catcataaca gcaaaatctt cctgctgggc tacaaaatta ttggtaccat
    59281 caatgggatc aatgacccaa accttgccct cttgaaccga ggctcgcaga caaccttctt
    59341 cagcacaaat cttatcctca ggataacggg acaaaatctc accaaccaag agttcctgaa
    59401 cttctttgtc cagtctggtc accaaatctg ttggagagga cttggtttca acacgcaagt
    59461 cttcctgcat atggtcaaga atgtactgac ctgctttctt aacaagctct ttagcaaatt
    59521 caaatttact ttccaagaga aatctttcct tccccttttt ctttggcagc ctgaactgct
    59581 cggtaaagtg aatagccact aaccgtttca aattctcgtc ccaaacgttt ctcttcgctc
    59641 ttgcttggca cgaccgcttt gaatccctta taggagtcca gtaacttttt agcctctact
    59701 ttgccttcat aggcagcttc aacatcatta aaaaaagaaa gcactgaagc aagttcttca
    59761 gtgctccacg acaaatctag tgggtaacta tactgtttgt tcattaacta ataccagctc
    59821 tcattcttgc ttcttttagt tcttgcttac gataactacg agggagaaaa gcacgaatct
    59881 catcttcatt aaaaccgatt tgcatacgct tggcatcaat aataattgga cgacgcaaaa
    59941 gactaggata ctgctcaatc aaatgaagca attccgatac cgaaatactc tctacatcaa
    60001 tattcaattt ttgaaaaatt tttgaacgag ttgaaatgat gtcatcagta ccattttcgg
    60061 tcaaggaaag gatgtgttgc aattcttttc ttgttaaagg actggtcata atattgtgtt
    60121 ccacaaaggg aaccttatgt ttttctaacc aggccttagc cttacgacat gatgtacagc
    60181 tcggtgatag aaatagtgta atcatgcttt tctcttctta tctatacttt gctacttcta
    60241 ttatacaaaa aaataaagcg cttgactagg gatttttaga aaaaaaagcc tatttttcaa
    60301 gaaaaatagg ctttttgcga acgattgaca caattggatt tggttaattc actcttaacg
    60361 atggttttaa acgatatata tttttatata tgcaaattaa aaacatcttt catttcattt
    60421 cctacgactt ttcagacaca gatagccaaa gaagctttca tagagggcaa aaaagaggag
    60481 gaaggcatga agaaagaagg tctctggcaa aatcataata acaggatcct tggctggatc
    60541 aaaaagccag gtatcatctc ccacaaagag aatttgatgg aaaagagtaa agaattggtc
    60601 aaaaccaatc aaaactcccc caagtccaat catcacaggt aagactacta gagtcaggag
    60661 actttttcga taaagagaca aaaagtcctt tttcacaatt ctattgacaa agacatagaa
    60721 acttggcagt gtcactagag ctactagctg aaccaaatga aagagattct tgaccactgc
    60781 gaaatggtgc agaccagctg ctgacgaacg aaaatcaggc atctgtaaga cctgactaaa
    60841 aggattggtc agataattca tcaagatatg aaaattgtat tgaatggttt ctggttttag
    60901 atagactcga ttcgttaagt ttagccactg aatctccata ggatagaaaa tccaagccag
    60961 ataaatggtc agaaggattg agagggagag gagaaagagc atagagcccc aaaagatcaa
    61021 tttagttttc atcaaaatcc cactccgcaa ggctagaaac cacatgtgtc ggtgcgattg
    61081 gcaggccagc tacttcttct gccttagtaa aacctgtcgt caccaagagc gttggaatgc
    61141 cattgtcaat cccagcccgg atatcagtca aataattgtc cccaaccata attaactctt
    61201 cacgttccaa acctaagtgc tcaaccgcct tgtccataat gatggcattg ggttttccga
    61261 tataaaccgg cttcactcgt gtcgctactt caagcagcgt aatcagggag ccagcacctg
    61321 gcaaaagacc acgttccgtc gggatgttga ggtcaggatt ggttccgata aaatgggcac
    61381 ccttttgaat agcaagagtt gctgtggcaa atttttcata gtcgacttgc caatccagac
    61441 caactaccac gtaggcaggg ttttccttgt cttccacata accagccgcc ttgatggctt
    61501 ccttgagtcc tgcttctccg acgacataga cggtcttttc aagccccaaa tcattcatat
    61561 agtcgatggt tgccaaagtc gctgtgtaga cagtcgatag gggcgtatcg atattaaaat
    61621 tctgagccaa catctcctta acactctctg gagtgcgagt tgtattgttg gttacaaaga
    61681 gatagggaat gtcccgcttt tgcaattcat gaacaaaagt ctctccagca gggattcggt
    61741 ctttcccctt ataaatggtt ccgtctaaat caattaaata gcctttatat ttcatctatt
    61801 tctccctaag ccttttttat ttctttccaa gtaatgattg cttgggcatt gataacccca
    61861 tcacttgtaa tttcatgctt gctttccagt ccagtccgtt caacagccga tgtaatcacc
    61921 ccacctggtc gaacttcctt gacatacttg aggttgattt tcttgggaat atagtgggtc
    61981 aaaaaatccg ctcccatgac ctcaaaaatc cagtccaagt atttactgtt attgacatga
    62041 ccattcatat ccaagtcgta aaaacgaaca tggtaatcct tgctgatcgg ctcttccaag
    62101 gactcatact tcggtccacg gataagtttt ttatcaaaat cagactggta aggagccaca
    62161 atctcaggtt caacagcatg gacttttcga ctgtcgcggt ccatgagaac aaaggtcgcc
    62221 atcatatgga tgagctcctg ccccgcttca ttataaatag taaagcgacg gtagcaaaaa
    62281 agtcgattgt agctcaaggc ttccgtttcg atggtaattt cttccgcaaa acgaggcaaa
    62341 cgaaccacct caatatcata ttctgcgata atccagacca gattatagtc ttccaaaatg
    62401 gccttatcac taactcccag ttcaatcgac tgcatccctg aaacttgcag tgacagcaaa
    62461 atcacatctg gaagtttgat atgaccgttc atatcagcca tatcaaaagg aattttcatt
    62521 ttcatttgat aagttaagcc catgatccta ctccaaaata aatcgttctg ctacagtatc
    62581 tcccaaaaag agacctctct ttgtcatgcg aacgtggtca ccctcaatct gcatgaggcc
    62641 ttgttgaacc aaatctctga caatttctcc ataaagtcca gcaaaagact gtccaaattt
    62701 ttcctcaaat cgcgccatgg aaaccccgga tttcttgcgg agtcccaaga acatttcttc
    62761 ttccatttgc tccttttgac tcaggtgatc ttctgtaata caagcattgc cttcctcaac
    62821 cgcactgaga taatgacgaa tgggaccatg atttttataa cgtactccat tgacataacc
    62881 agatgcccct gcaccaatac catagtattc agcattgtcc cagtacatga gattatgacg
    62941 actttcaaag ccgggtttgg agaaattaga aatctcataa tgctcaaaac ccgctcgctc
    63001 cagctctgca atgatgtact caaacatctc cgcttctagt tcctccttag gcagaggcaa
    63061 tttcccacgt cgcatccggt tcataaagac cgtatggttt tctaaaatca aactatacaa
    63121 actcatgtgg ggaatatcca gtccaatggc tttagccaca ttttccttta cttgctccat
    63181 ggtctgacca ggcagagcat aaatcaaatc aatggagatg ttgtcaaaac cagccagttt
    63241 caggcgatcg atattttcat aaatatcctt ctccaaatga ctgcgcccaa tctttttcaa
    63301 catcttatca tcaaaggtct ggacacctag cgaaacacga ttgacagccg aatttttcaa
    63361 aacagctatc ttatccgcat ccaaatcgcc tggattggct tcaatggtca actcttccaa
    63421 gacagacaag tccaagtttt tagtcaagcc attcagtaaa acctccagtt gcggagccga
    63481 cagggctgtc ggtgttccac caccgatata aagggttgac aacttttcaa tatcataaga
    63541 acgaaactct tccagcagat gctctaaata gctgtcgact ggctgatttt tgatgaagac
    63601 ctttgaaaaa tcacaataat aacaaatctg ggtacaaaat gggatgtgca cataggctga
    63661 cgttggtttt ttctgcatag taattattat accacaaaga ctagattcca gataaaaatc
    63721 accatcccca gatacatagt ccgtccggag atggtgatgg tttattcttc tgttatatca
    63781 atcacaatct cttctgagtc atcaagagct tcggcttttt cttgccattg ctccttgaga
    63841 ttatttaatt gattttttga tgcttctgtc gcttgaagag cataggattt agcttgagca
    63901 agtatactgt ccacagtgat ttcacctgac tcaacctgtt cttttgtttt cagaacaaaa
    63961 tctgtagcct gctccttaac ttctgtcagt ttttcacaga cttgctcctt ggcatactcc
    64021 ggatcttctc tcaaatcatc tagaaaatct tgagcctgac tgcaaacttg tttgccctta
    64081 tcacttgtta aaaacaaggc aagagctgca cctgaaacgg ttcctaaaag gattgaggat
    64141 aatttaccca taaggattct ccttttttat tttttgaaaa atttacttgc aagacgaaga
    64201 gctgacagac ttgcaccagt cttgagtgtt tttgaaccag ctgatgaagc tttcttgctc
    64261 aagacacgcg catggtcatt gaggtctgaa acagatagag ataaatctgc aacagcactg
    64321 aagagtggat caatcgtagc caccttgaca ttgatatcat ctgccaagac attgacctta
    64381 gccaacaact cattggtgtg atgcaaggtc acatccacat ctgaagtcaa ggttttaatc
    64441 gtcttttctg tttcatcgat gacacgacca agcttttgta cagtaatgat cagatagacc
    64501 aaaaagacaa tcaaagctag ggcaacaaga atatatgcaa cttctaacat ttagttttcc
    64561 tcctctgtaa tatagtaagg ggccttcttt cgattttgat aaataacgat cattataccg
    64621 agaccgataa ggacaactga cagccattgg gacactcgaa ggccgaagaa catgagacta
    64681 tctgttcgca taccttcgat gaccatacga ccgaaaccat accaaatcaa gtaaaaggcc
    64741 gtgatatgac ctcgtctgag actcttccat ttccgtctaa aaatcagaat caaggcaaag
    64801 ccaagcagat tccatagaga ctcataaagg aaagtcggtt gacggtagct cccctcaata
    64861 tacatctggt cacggataaa gccaggtaga taatccagat tatccactgt tgcaccataa
    64921 gcttcttggt taaagaaatt accccaacgc cccaaacttt gagcaatcat aacgctaggc
    64981 gccgcaatat ctagaaaatc ccaagtattg atgagtttac ggtcagcaaa gatatagagc
    65041 acaagagccc cagttatcaa accaccgtaa atggccaaac caccattcca aatggcaaaa
    65101 atctctccta aattctgact atagtaatca aatcggaaaa taacatagta gagacgagct
    65161 cctaaaatag ccaagggaaa agctactaag ataaaatcta aaatatcgtc tggtatgatc
    65221 ttctttctag gtgcttcttt catggtcaaa taaaccgcaa gaatcaagcc tgtcacaata
    65281 cataaggcat accaacgaat ggctaggggt cctagttgaa tagcaattgg atcaagcatt
    65341 ttgcacctca tttcgagcga tgagacttgt cagtcgttcg tcgaacaaac gggtcgcatc
    65401 aaagcccatt tccttggcac gataattcat ggcagctgcc tcaatcacaa cagagatatt
    65461 acgacctgtt ttaactggaa tacgaatacg aggaatggct acgccagaaa cttcaagttc
    65521 ctctgcattg tttccaagac gatcaaaggt cttatgcgta tcgtaatttt ccaaatagac
    65581 agcaagctga acctgtgaag aatccttgac agcactcgca ccgtagagac tcataacatc
    65641 gataatacca accccacgaa tttcaatcaa gtgtttcaaa atttcagctg gttcacccca
    65701 gagagtaatc tcatccttgg caaagatatc gacacggtca tcggctacca aacggtgacc
    65761 acgtttgaca agctcaagac ctgtctcgct cttaccaatt ccactatctc cctgaatcaa
    65821 gacgcccatc ccataaatat ccatcaagac accgtgcaca ctggtacgtt ctgccaaacg
    65881 agaatccaga tagctagata actctccaga taaacgactg gtagctgcac ggctggttaa
    65941 aatagcaatc ttacattctc tagcagcctt taacatctcc tctggaacca ccaaaccacg
    66001 ggcaacaatg actgctggtg tctcaggtag aaacattttt ttcaaaactt cataacggct
    66061 gttggaaggc atgctgatca gataagacca ctccttcatc cccaaaagtt gaatccgctc
    66121 tggtgtatag tagtcaaaat agcctgtcat ttcaagacca ggtcgcgtaa tatccgctgt
    66181 attgatttcc ttttcaagca attttggttc accatagaca atgtctagtc taagcttttc
    66241 aatcacttct tttactaaaa ccgacatcat ttcctccttc aaatgagttc ttctctctat
    66301 tatatcaaat tgtaggagga agtttcagat ttttgcaggc tttggagtat ttatttaaaa
    66361 gaaaaaggac tagatttctc tagcctttca ttccaattag aattttttac gtttacgagc
    66421 tacttctgat ttacgtttac gttttacaga aggtttttca tagaattcac gtttgcgtgt
    66481 ttcttgaaga gtaccagctt tagtaaccgc acgtttgaaa cggcgaagtg cgtcgtcaag
    66541 agattcattc ttacgtacta ctgttttaga catttttttc actcccttca agttcaatat
    66601 ctatttcatt ctacacgtaa aaggaataat tgtcaagcaa aaatgcggtt taattttgat
    66661 tttttcttcc atttatacaa gagttgaaag cgttcaatag attgcttttt tatttttcga
    66721 gtaagctaag cgcttcagca tctgcgatga tggttacatc agggtgattt tggaggctac
    66781 ttgcaggtag gttctcagtc actgggccag atactgttcc ggcaatggct tctgctttcg
    66841 actcaccgta agcaaaaaga ataatagact tggcatccaa aatgttttta atccccattg
    66901 aaatagcttg ggttgggacg tcttcaatct tggcaaagaa gcgtgcattg gcttcgatag
    66961 tagactggtc aagttctact agatgcgttt gactgtcaaa tggagtacca ggctcattaa
    67021 agccgatatg cccattgcga ccgattccca agatttggag gtcaactgga tggtcagcca
    67081 aaatttggtt gtagcgttca acttcagctt cagcattgtc cttaacacca cgaggcaaga
    67141 aactttcttt aaatggtttt tggttgaaca agttttcttg catgaagtaa cgataagact
    67201 gtggattgtc cccatcaagg cccacatact catcaaggtt gacactggtt agatttgaaa
    67261 aatcaaggtc actctcaaca atttccttgt aaaattcaag tgggctactt cctgtcgcaa
    67321 gtcctagagt ttgagctcca ttagccaatt tttccttcaa aatctcaaaa gcaacttttc
    67381 caccttgaac ttggttttca actttaataa ctttcatctt ttcatcctcc atttctgtct
    67441 atatttatta tatggtatag accaattttt gtcaagtgaa aacgatttaa tttctaaaaa
    67501 aagagcgtcc aaacttgaaa cgtgttataa tggataggat tagaacttag aaagaatgaa
    67561 cagatatatg aatacagctg attttgattt ccacttgcca gaggaattga ttgcccaaac
    67621 gccccttgaa aaacgtgatg cctccaaact cctcatcgtc aaccgtgaga caggagaaat
    67681 gcaagataaa cacttccact ctattattaa tatgctggaa cctggtgatg cccttgtcat
    67741 gaacgacacc cgagttctcc ctgcccgcct ctatggtcaa aaagtggaga caggaggtca
    67801 tgtggaactt ctcctcctta agaacactag tggagacgag tgggaagttc tggctaaacc
    67861 tgccaaacgc ctcaaggtcg gtactcgtat cagctttggt gatggccgcc tcagcgctgt
    67921 cgttacagaa gaattgaccc acgggggacg cattgtccgc tttgaatacc aaggaatttt
    67981 cctagaagtc ttggaaagtc tgggagaaat gcctctgcca ccttatatcc acgaaaaatt
    68041 agatgaccgt gaacgttatc aaaccgtcta cgccaaggaa agcggctctg ctgcagcacc
    68101 gactgctggt cttcacttca ccaaagaact gctggcagaa atccaagcta agggtgttca
    68161 tctagtctat ctgactctcc atgtcggact cggaaccttt agacctgttt ctgtggataa
    68221 tctggacgaa cacgaaatgc actcagagtt ctatcaactt tctgaggaag ctgctgccac
    68281 ccttcgctct gtcaaaaaaa atggtggtcg tgtcatcgct gtcggaacca cttctatccg
    68341 caccttggaa actattggtt ccaagtttga tgggcaaatc caagcagatt ctggttggac
    68401 caatatcttt atcaaacctg ggtatgagtg gaaggtcgtg gatgccttct caaccaactt
    68461 ccatctgcca aaatcaactc tggtcatgtt ggtttctgcc tttgcaggcc gtgaattagt
    68521 cttagatgcc taccaccatg ccatccaaga acactaccgc ttcttcagtt ttggtgacgc
    68581 catgtttatt tattgagaaa gaatttctct aattcttcta ataccaataa atcgctaaga
    68641 tattatttca aagaacatct acaattgaaa ctctagctag ctgtagaaga cgcctagtac
    68701 attgaaatta aaatgcttcc ccctagcttc gaaaatattg ccatagattg cgttgactct
    68761 ccaaattgat tcatctatat tttatttcag cttcctatat tttcttcgct gtttgtaaat
    68821 caaaatgcaa gacacatgag tagcaccata tttgttactc ttatctgtcc tctcaagaga
    68881 ctattatgag ttatttcaga atcattcact actttgaccc tgactctcct tagtctcaaa
    68941 atcaaagact tatactcttc aaaaatctct tcaaaccgcg tcaacgtcac cttggattat
    69001 atatgtgact gacttcgtca gttctatcta caacctcaaa gcagtacttt gagcaacctg
    69061 cgactagttt tctagtttgc tctttgattt tcattgagta ttaaacaaaa agtgaacaaa
    69121 tctgaattct aatgtacaga agactaggct tgttcacttt tttatagtcg ctataagatg
    69181 accttatcta tggcttttta tatataatta tatattcaga catactatta tcaattttgt
    69241 cgcagggagg aatctgttaa cgcacccatt caccattatc attgactcta tagccatcta
    69301 tacttgtatt gaccgctaac tcacccgatg catttacata ataccattta ccaccaactt
    69361 ggaaccattg attgactttc atagaaccgt tgctgttgag gtagtaccat gaactattaa
    69421 cttgtaccca acctgttgcc atggaaccat cagtattata aaaataccac atgccatttt
    69481 cttgtttcca gtctgttgtt ggagcaactg ctttagctgg ttctactgct acatctgttc
    69541 cttggttaga tgtaacagat acaggatacg aaggaataga tgattgctca ggaacaacaa
    69601 ctttttcagg ttctctcgtc cctctcctta tacgtctttt taccatctct ttagtaattt
    69661 gacgagaagt agtttcttca attgttccat cacgttcatc tacagtatag attgtagtaa
    69721 gagtaattta ccaatttctc ctacttcttc tacttcttga cttttatcaa gagttgggcc
    69781 atcgagatat tctgtttcga ttggaatttc ttggacaaga acttggggct tggttctttt
    69841 tttaacaact cttgtttgag agtctttttt ttgacttaaa gtactctcag ttacttgtcc
    69901 actctttcca tctacattat aagttatcgt tgtaactgtt ttcccattct ttcctagagt
    69961 aatctcttgc tcctgtcctg cagaaaggtc attgtctgct tcatatttag tagcaaatgg
    70021 aacaagaact tcttcaacct tgcttttagc tggaactttg ataactgtat ccgtggcttc
    70081 ttttctatca acagtaacct gttcggtaac ataaccagtc tctggattaa catcgtaggt
    70141 ccttgtcgta gttacatagc catcctctcc atcaattgta acaggatttt cactacggtc
    70201 ttttgtttca tctttttcat aacgaattcg cgtacttgaa attttcttgg ttactacctt
    70261 aggtttagtc gctactttta caataatatc cccattgtca gcgtcatcat actctattcc
    70321 ctcttcttta tctctagtat catctctgac atattgaatc ccatcagcag catgaacaaa
    70381 acttgtattc agattcctcc taaaaataaa gttagcccga ttaccgcaga accaaaaatc
    70441 tttccgagtt tacgtaatgc atagcgctta ttggtattag attttgccat tacatcctac
    70501 ttctaaaagt tactacttct agtatagcat cttttctatc aaacgttaaa cagtatactt
    70561 tatatatcaa atatacttag aatgatatat tgattattga actaacgctt taactatatc
    70621 gtaatcaatc tcatatataa aggattgcag acatcttatc taaatacatg ctaatatatt
    70681 tagatacaaa cattccaact tgataacttt cactcatctt tcatcattcc ttatacaact
    70741 atgcagtata aatagaatag ttttctcatc agaatgagac tattttaata ttagatattt
    70801 tgatagaaaa aacatgaata aaattggttg aatttaattc cctaactcga tagaggattc
    70861 tattttaaat ttaacaacag ctaggattac actataaaaa gtacattacc acctgttcgg
    70921 ctggagaatc tagtcgatta gctccctctt agttacaagc ttaaagcgat tttttaacta
    70981 atactaaacc agattaaaga aggaactaga acatctgtct tgtactaatc aatatgctat
    71041 tttaaagttt caaataaact tggaatgcta attattatat ttacaataaa tagttgactt
    71101 cgatagaaac agaaaataga attcaacatt cttccctact tataccataa taaataagat
    71161 ccgcaagata gccttttctc tctacaccat taacaatggt ttgtagatag gacattccag
    71221 ccttttccat gacacgacct gaagctgggt tgagactggc ataacgtgct ctgacctttt
    71281 gaaaacctgc ttgagtaaaa caaaagtcca agatagcttt caaagtctct gtcatcatac
    71341 catttcccca gtaagccttg cctaacacat agccaatttc acagcttaaa tcagcctcgt
    71401 ctatcttaac aatgctgata tctcctatca cttgctctgg gttttctttt agacaaatgg
    71461 cccatttata atagttgaga ttagtatagg aagcaaccca attgcaaatc gagtttcgag
    71521 tgatttcgac atcaggatgg ggatcccagg taacataggt cagattctca gcggatgaag
    71581 cccaattttg aaacatggct tctgcatcac tctccacaaa tcttcttaaa atcaaacgtt
    71641 ctgtctgtaa tatttgcgta ccgatagatt tcatgatgct acctcacttc cttatttcta
    71701 tgctcgtagt aaaaaggctc aactcagtaa cagctagaaa acgagtttgt cttctaattt
    71761 cttgacgcag tcgctgcctg gtttgaaatg cgctctagca atctttttca aacctagtca
    71821 tcgttgcagg ggtaagacga tgaaatcgaa ctcttcgagt taccgaatct gcctcatttt
    71881 cttatttcaa gatgagaggc tgaaaacctc cagtggaggt ttttcttgct ttttaatttc
    71941 agggcaagaa gctaaaaagg tcccccggac cttcttcgct ttctcatttc taggctcagg
    72001 gtaaaaacct ccaatggagg tttttactcc caaaagtcat caaatacggt gatgggtaag
    72061 tggcgtttgt gttggccttt gtgccaccag ttttcaatgg tcgcttgagc ttctgggctg
    72121 attgttttgc cttctaggta atcgtcaatc tctgcatagg tgactccaag tgcgacttcg
    72181 tcagctaggc ctggtttgtc ttcttctagg tctgccgttg ggattttttc ataaagggct
    72241 gggtctgcac caagttcctg taagagttgt tttccttgac gtttattgag gcggtaaaga
    72301 gggagaatat ccgcaccacc gtcaccaaac ttggtaaaaa agcctgtgat attttccgcg
    72361 gcgtggtctg ttccaatgac cgctccgcta tgggaaccag caagggcata ctgagcaatc
    72421 atacggcaac gtgccttgat attccccttg ttgaagtctg aaacaggact acctgtcgct
    72481 tcaactgcag ctgtcatggt atcagctgat tccttgatat tcacaaccaa gctgacatct
    72541 ggctggatga aggctagggc tttttgagca tctgcttcat cagcttgcac tccgtatggc
    72601 aggcggacag cgataaattt gtagctgtcg tctcccgttt cagctcgcag ttcttccata
    72661 gctaattgcg ccaaacgccc tgccaaggtt gagtcttgtc ccccagaaat ccctagtaca
    72721 aaggttttta ggaagggatg ttttttcaga tatcttttta agaaatcaat agaacgacgg
    72781 atttcttcct gggcatcaat cactggtttg acacccagct cttggataat cgtttcttgc
    72841 aaactcattc ttcttctcct tcaccaaggg cttccttgcg catcttatca atcaagtcca
    72901 tcttatcttg ccatacatca cgcgccaaat ccactggata gtgctgcgga ttgagcacac
    72961 gcttatactc atcccacaac ttgtcaaatt ccttacgggc ataatcctga atgtcagtca
    73021 aactaggcaa gttgtaaact aatattcctt ctttgaagat atccaccaag agaggaacgg
    73081 catcaaaatt acgaaccgtc ttcttgatgt atgtataggt cggatggaac atcttgattt
    73141 ctgtcatgtc gctaatatcc acaccatcat aagtgatata gtcgccttct gacttgcctt
    73201 tttcacgact ggtaatgcgc cacacctgct tcttacctgg cgtagaaact ttttcagcat
    73261 tattagacag cttaatcgta ttgcgcatct gaccagtttc atcttcgatt gcaacaatct
    73321 tgtaaactgc accaagagct ggctggtcat aagctgtaat cagcttggta cccacgcccc
    73381 agacatcaat cttggccttt tgcatcttga gattgaggat agtattttcg tccaaatcat
    73441 tagaagcata aatcttagcc tctgtaaatc cagcctcgtc cagttgctga cggactttct
    73501 tagaaatgta ggcaatatcc ccagagtcaa tccgcacacc cataaagtta atctgatcac
    73561 ccagctcacg cgccacctga atggcagctg gtacaccgat gcgaagggtg tcataggtat
    73621 ccacaagaaa gacacaattt ttgtgggtcg cagcgtaagc cttgaaagct tcatagtcat
    73681 tgccataaac ctgtaccaag gcatgggcat gggttcccaa aacaggaatg tcaaagagct
    73741 tacccgcacg cacgttgctg gttccattgg cgccaccaat cacagctgcg cgtgttcccc
    73801 agatggccgc atccatttct tgagcccgac gtgtcccaaa ctccatcaag ggttcatctt
    73861 cgataaccga acgaatacga gctgccttcg tcgccaccaa ggtctggtag ttgacgatgt
    73921 tcaaaagagc cgtttcgacc aactgacatt gggctagagg tccttccacc tgcacaatcg
    73981 gttcattagc aaaaaccaaa tccccttctt gggcagaacg aacggtcaac tccaacttga
    74041 aattgcgaag gtaatccaag aacgccccat gataaccaag cgactccaaa taggctatat
    74101 cactatctga aaaacgcaag tcttcaagat agttcacaat tctttccaaa cctgcaaaaa
    74161 ccgcatagcc gttcttaaaa ggctgttggc ggaaatacac ctcaaagacc gccttcttat
    74221 tgtgaatccc ttggtcaaag taaacctgca tcatgttgat ctggtacaag tccgtgtgca
    74281 atgtcaaact atcatctgga tacatacttt tcctacttcc ttagctagaa acccatgaaa
    74341 attttcaaga actttcatgt attccaataa attagtacta ttatatcaca ttttagctgg
    74401 attgagaaaa gagtaacaag ctattctcca ctctccaatt catccatatc ttgttcaaat
    74461 tttttctgag cccattcgcc atagctctta agaccaagat tgccaataaa gacccacgga
    74521 aggtaaatga catatgtaat gaccccagca gacaggtatt taaaattcaa aggattgtgc
    74581 tgataaattt ctatgttgaa ttgataattc tgcaacatca aaagagccgt aatagccaag
    74641 gttaggaaaa aacaacccaa aatcgtaaaa tgaaaacgac tatagtaggt cactcccaga
    74701 taacgggcgc gattgaaaaa gtaaaatgtc cctatgatga taacgattag cagcatatta
    74761 gaattaaaaa ggcttggtgc taatactgaa atgatataag ataggagcga caaagcaatg
    74821 cagatataga aactttcaga gcccgcttta ttgaacagtt gttcttctct ttcgtctagt
    74881 aattgataat aataaaatct atttttcatc ttcttcctcc caaaatagtt ggtctagggt
    74941 tttccctaaa catctgcaaa tagactggca gagcgagaga ctgggattgt attttcccgc
    75001 ctctatcaaa ccaatagtct ggcgtgtcac cccgacagcc tctgccagtt gaccttgtgt
    75061 taaatcacgc tctacccgag ctaattttaa ttttaaattt ttagccacct tcgtcctcct
    75121 tatagtttta atactcatct actcttaaaa aatccaaaac caacacaagc tatcagctat
    75181 ttattataac cccattaatt tgcactccag tattatcttc agccgaaaat cagtatttta
    75241 ggttgtttga aataaacttc ctagtttact cttttatttt tatttagtat tagctttagt
    75301 agaatctttt aaacgagttt ttattgctta tatttcttgt ttagtttagt tggtttcata
    75361 tcactattat ataatgcttt tggaaatgag cctagtataa gtcaaaaacg tgttgaatag
    75421 tgaaagcagg agcataccaa gatgactgat ttttttattg tattttaggt atgcaaaata
    75481 atactaaatg aaactaaaat gaatacttct tgcttttctt gagagtgaaa aagtacaata
    75541 aaatgattgt agtgattacc acaagatact gactaataga catcgtattt gaagccacaa
    75601 atacaggtaa agaataaaaa ggaagaagtt caattgcttt gataaacaaa tcattactag
    75661 tattcatcat catcgtattt aatatattag ggataaagag tagtaaagct actaaaatac
    75721 caaatcccaa gccacttttc aatttgtata aatagaaaat gtaggataat agaaaataaa
    75781 acaggactaa caaaattgta ttgactacaa tagctactat aaaatctaat cctaaatcac
    75841 ctggaatacc caatttactt acgatgacta gtaacacaat gccattcaaa gcataaataa
    75901 tggaaactga gatggcatat agaaaattag acaagacgta aatcatccga ttcttctgtt
    75961 gattataaaa caaacttacc gtattgtggg aaaaatctct actaatgact cgattagcat
    76021 gtataacagc cattaacata ccgagcatag cataaaagtt tgaaatatgc ttaataccaa
    76081 gcgatgtccc ttgagtcttt agaataaaga atgtaagcaa tatcggcggt ataaacgaga
    76141 taagcaaact gagatatatt acgcctgatg aatataaatt tcttatattt tccttaagaa
    76201 aattcaattt atttaatttc atgattataa ccttccttta ttttgaacga tttaagtaaa
    76261 tatctttaag cgtctctttt ttagtttcaa aatcaactac tttaatagag ttttcgttaa
    76321 aaaatttaaa aaactcacta ctttgaatat tcccagacat agtaattctc agtccctctt
    76381 cctgaacaat atccccaaat tcttgtttgg taatgaaaat gtctctatct gtagctgatg
    76441 aaaaagctat ctcaaacaag aaattatgac tatcttttcc tactttttga aatgtcaaaa
    76501 gcccgttctc caagaaaaga actctctcac aaatttcttc aatgtcttct aatttatgac
    76561 tcgatattaa aattcccaca ttttcatgta aagctaaatt ttttagaacc gctaaaacta
    76621 tttgtgatga ttcaatatct aaaccattag tcggttcatc taaaatcaat atatcaggtt
    76681 ccgtaacgag agttagaagc aaagctaatt tttgttttgt acccaaagaa taggtcttta
    76741 cttttttatt aatagactga gtcaaatcta actcttggat caaacttcta aatatttctt
    76801 gattgtagtc aacaccatat aaatttgaca aatattttaa attctctaaa cctgttttag
    76861 ataaaaataa ttttggttct tcgattaaat acccaacatt atcactgctt ataatattac
    76921 ctgaagtcgg ttgattattc tgaacaagaa ttttcatcaa cgtactctta ccaactccat
    76981 ttctccctgc tagaccaaca atttcaccct tgttaagtgc aaaatttata tctttgagaa
    77041 tgattgaata accataatgc ttacttacat ttataactta cattttttat tcctccatta
    77101 atattcatgg tttgctcttt gattcttatt gagtttaaaa agttgcacct ctttttaaca
    77161 atattatatc atatatctaa cttaatgcaa tatataaatg tcattttgta aaattttatt
    77221 aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat ttttttcaaa
    77281 atatctaaga catcgcttct ttgtttaatt tgataggctt taatacctaa gctccgactt
    77341 tatcacttaa aaaataaaaa aggacagcta atctcttgcg catcaaggga tttcgccatt
    77401 ctttaatctc gtttaagtgt tgtatatgga gctttgcata attttttaaa actaaacaac
    77461 tacattaagc acgaactgtg acgctggttc catcttcctt ataaagattg ataagcccct
    77521 ctttaagagc tcgaaccatg tctccagctt gaacaggttg tgggacttta atagtcaata
    77581 gttccattgg atttggagcg cggtcgattt tattgccttt ggcatcatgc aaatcttcaa
    77641 tataggtttc aaaatgacgg aaacctggac cataaaactc aacttggtcc ccttcgttaa
    77701 tgacgtttcg ttgacgaata gttgctgttt gtgccgcatc atcataagaa accacttcag
    77761 cgacaaactt gtactcaggg attttacgac gagcaccaaa caactgctca ttttcagatg
    77821 gtgtaccata gtaaaatcct gtagccagtt cacgttgggc aaccttccac atctcgtcca
    77881 ccaagtcttg tttgatagct tcaaactttt caggactttc aagataggca tccacagccg
    77941 ccttgtagca gttggttact gttgatacat agtgaataga ctccatacgt ccttcgattt
    78001 ttagactgtc cacaccattt tcaatcatat ctgagatatg gtcaatcata gacatatcaa
    78061 cggctgacat tgaaaattct tctggaatct caccctgcaa actcttacgt tctttcccaa
    78121 atggcatatc gtaaaggtcg tacttccaac ggcatgactg agaacatcca ccacggttgg
    78181 catcacgcat actctagacg gattgttttg acaattctaa ccttttagac tttgcataat
    78241 aactgttaaa cagtcgaaaa ttaccccagt tttaacaagt agtcaaaata ccagataaag
    78301 taaaaagggg ctaggaaaaa agtctttaaa atcttaaaaa cgcatagtat caggtattga
    78361 acaatcttga tattatgcgt tttattgtgg gaagatttac ttcattttct cttggaattg
    78421 agttttctcc tacttcaaaa ctagatgatt tgctatttaa aatagcgttc cttatgattt
    78481 tggcaacctg gattaaagcg agaaaaacaa aagaggcaac ttaagctttc tttatattgc
    78541 ttatatgtta atagttttag acaaacacca cataaaatag gcttatcctg tatcaaagat
    78601 aagggataag gctcaaaagg gtgattttct aatgaatcat gacaccgata acaagcataa
    78661 tactttttac aatcatagca ttgtaaagca ataatatcca gcttgctatg gtaatgaatg
    78721 catcttgttt gcttatccac taagaaaccc tgtgcctcta tcatttcctt ttcctttctt
    78781 aagctcgaac tgtgacgctg gttccatctt ccttataaag attgatgagt ccttctttta
    78841 atgcacgaac catgtctcct gattgaacgg gttgtgggac tttaatagtc aatagttcca
    78901 ttggatttgg agcgcggtcg attttattgc ctttggcatc atgcaaatct tcaatatagg
    78961 tttcaaaatg acggaaacct ggaccataaa actcaacttg gtccccttcg ttaatgacgt
    79021 ttcgttgacg aatggttgct gtttgtgccg catcatcata agaaaccact tcagcgacaa
    79081 acttgtactc aggaatttta cggcgagcac caaacaactg ctcattttca gatggtgtac
    79141 catagtaaaa tcctgtagcc agttcacgtt gggcaacctt ccacatctcg tccaccaagt
    79201 cttgtttgat agcttcaaac ttttcaggac tttcaagata ggcatccaca gccgccttgt
    79261 agcagttggt tactgttgat acgtagtgaa tagacttcat acgtccttcg atttttagac
    79321 tgtccacacc attttcaatc atatctggaa tgtggtcaat catagacatg tcaacggctg
    79381 acattgaaaa ttcttctgga atctcaccct gcaaactctt acgttctttc ccaaatggca
    79441 tatcgtaaag gtcgtatttc caacggcatg actgagaaca tccaccacgg ttggcatcac
    79501 gcatactcat gtggtttgaa agagtacaac gtccagagta tgaaatacac atagctccat
    79561 ggacaaaggc ttcaatttca acatctgtac gtttgcggat ttcagctaat tcttccattg
    79621 aaacctcacg cgctaaaacg acacgagtca agcctagctc tttccagaac tcaagggttt
    79681 catagttagt ggcactggct tgggtagaaa ggtggatttc aagacctggt gcttcagtcg
    79741 ctgcaatcat aatcaaggct gggtcagata cgataactgc tgcaatcccg atatcacgca
    79801 gtttacggaa ccactcacca gcaccagctt catttccttc gtgcataacc atattagccg
    79861 ctacatagac cttggcacca tacttggccg caaactgcac gccttcttcc atctgttcga
    79921 aagtaaagtt tcccgcacgg ctacgaagac cataggcctg accaccgata aagacagcat
    79981 ctgctccata ctgaacagct acctttagct tctctaaagt tcctgcaggt gataaaacct
    80041 caggacgttt taatgttttt gtcatgattt ctcctatttg caatataaaa gtttgacatt
    80101 tttccttctc attttatagt aaataaagga taaaatcaag cctagacgga ttgttttgac
    80161 aattctaatc ttttagactt tgcataataa ctgttaaaca gtcgaaaatt atcccagttt
    80221 taacaagtag tcaaaaagtc tagaaaagta aaaaccagta tccaaagata ctgactcgta
    80281 aaaatacata aattagtcct tagatgacta ctcccactct gttgctccta taatggaaaa
    80341 ggattgatac agtctagaat atcgcttttt tatttattat tctgatataa aactgttaga
    80401 attgattttt tgttttatac ccaaatatga atagagacgt agctaataag ttgaataaca
    80461 tatttggaaa aatgagaaat agcaatatta ctagaacttt tagaaacaat caatatttaa
    80521 aaagaaaaaa gctcaaagaa tttattaaac catgttataa tagatatagc tataatttta
    80581 tttataacaa gaggatagaa atgaccgaat tagaaagaaa aaatcgaaaa attagctaag
    80641 aaatattctg ataacttaaa catcaaagtt caagagagag ttcgtgaaat ggcaaatgat
    80701 aataagagcc attatttgat atacagagtt ttaggtattt catttgaaga aggagaaaat
    80761 atcgatttgt atcaaaataa aggtcgtttt ttatacaaat atgctggttc atttttagaa
    80821 gaagctgcag tactatgctt taacgaaaaa tttggtacag aaaatactta aaaagttaac
    80881 attcctaatt ctgaaagtac aaaacctaag acttttgaaa ttgattgttt agtcggagaa
    80941 aaacacgcat acgaaataaa atggtgggat gcaactacag atggagacca tataactaaa
    81001 gaacacacta gaataaaagt tattcataac aaaggatata taccaattcg gttaatgttc
    81061 tactatccaa atagaactca agctataaaa attcagcaaa ctttagaaac attgtataac
    81121 ggtattggag ggaaatatta ttatggagat tctgcctggg aacatttaag agcagtgacc
    81181 ggtattgatt tacttagtat tctaacagat attgcaaata aaaaaacagg ggtaaaatca
    81241 aaatgacagt attaaaagga gataacttag aaatattaaa aactattgaa tcctcaagta
    81301 ttgatttaat ctatatggac cctcctttct ttacacagaa aacccaaaaa ttatctaata
    81361 acaaaaatat tatgtattca ttcgaagata cgtggacttc gattgaggat tacaaagaat
    81421 ttttgtctgt aagattagaa gaatgcaaaa gagtgctaaa aaatagtggc agtattttcg
    81481 ttcattgtga taaaattgca aatcatcata ttagattaat tttagataat atctttggag
    81541 cagatatgtt tcaaagcgaa attatatgga actataaacg gtggtctaat tcaaaaaagg
    81601 gattattgaa caatcatcaa aacatttact tttattcaaa gtcaaaagat tttaaattta
    81661 atacaatttt tacagagtat tcttctacta caaatatcga ccaaatacta gtagaacgaa
    81721 aacgaaatgg aaactctaaa actatatata aagttgataa taatggtaac tatattctag
    81781 caaaagagaa aaatggagtt cccctttcag atgtttggaa tataccattt cttaatccaa
    81841 aagctaaaga aagagtaggt tatcctacac aaaaacctat tctgttatta gaacaaatta
    81901 taaagattgc tactgataaa aatgatatag ttttagaccc gttctgtgga agtggaacta
    81961 ctttagtagc ctccaagatt ttgaatagaa attatatggg gattgattta tctgaggaag
    82021 ctatcaatat aactcagcaa cgtctggaaa atgttataaa aacaagttca aatttattga
    82081 ataaaggaat cgaagcatat agaaccaaaa ctgaagaaga ggaaaacatt cttaaattat
    82141 tacaggcaaa aattgttcaa agaaataaag gaattgatgg ttttttacct aaacattttc
    82201 aaaaaaaacc gatacctata aaaattcaaa aaaataatga atgtctgaat gagagtatct
    82261 ctttattaca gaatgctata aactccaaaa aacttgattt tggagtagtt ataaaaactc
    82321 attcagataa tttattattt gattttgata cgatccctga aaatataata gtagttgacc
    82381 attttgaact tacaatcgaa aaatggttaa gtaaaagtca acagttacta tagtttgcaa
    82441 attatttaca gaaagaacaa aaatgctctg aaacactgat ttcaaagcat tttttgttag
    82501 tttaaaatta ctcccattct tcttttccaa acgtacaata tatccaaaac cattcaaaat
    82561 actagattct attttttata atatcactaa atccacctaa ttataggacg ttttcagatt
    82621 tttagtcccg tcccagtccc agtaccggag aaatattgtt ttaatataat atctcttttt
    82681 gtcttctaag ctcttaaaag caaaagaaca agtaaagagt caagacaagg ataaaaagtc
    82741 catattaggg caaataaaaa gctttaagac agatgacaaa tctaagtcaa ataagaaaga
    82801 ccatagtaaa ggtgcagaga gataaatatt ggcggtcttc ggactgcctt tattttttta
    82861 tccatttttc aaatcaaatt tattcagact atatatgcac atatacactt aaattcatat
    82921 aaaaacatgg cttgtaaaaa attactttaa tcacaataat cgcatttaaa attgtgatgt
    82981 ttgcaagcta aattacggac ttcacttgga agttttccct tgtatctttt ataatagata
    83041 gaaaatttgc tggcagatga atatccaaca gattctgcta tctcttttat agatagttca
    83101 gtgtttaaaa gaagagtttc agctacattc attctttttc tttgagtgta ctctgtaatg
    83161 ctttgacaat atttttcctt aaataaattt tttaatttag taccactcat tttagatatt
    83221 ttttcaagcg tgccttgatt tacattcgtt gcaaaatgat catctaagaa tcttgctaca
    83281 tcttcaagtg ctttatcatc atcaatttca attttatatt tttttctatt taagtatgtg
    83341 tcaattacta tacttatcca ttcatttgcc tttgctttaa agaaaaaatc agcggcagga
    83401 gcgtccatct tacaatttaa tatttccatt gccactcttt ctaaggcctt tgtaagtata
    83461 atttgattag tttgaagtaa agccccataa aatgattctg gattaatgtt aatagatgat
    83521 agatgttttt ccaaaagttc tcttttaaat ccaatagaaa cacaaagata atatgaattc
    83581 tcgtgtaata aaaataggaa gtcatctctt atattgtcaa agtcaaaagt acataatgag
    83641 tttgcagtaa gtgtttgata aggactaaac ttttctccat ttgcgctgac tatgtagctt
    83701 gtgtatattg aaacataatc tgccatacta taggtactgt tttgaactac ttcttctctg
    83761 atataaaaat catgtatatc gataatgaag ctgcctcctt cataaaacca atataggcct
    83821 tctgcataag ttgaattctc ttttttccaa caaaatgtat gacctgcact tgaatacttc
    83881 tcattgtttt tacattcatc tactttcata taatctttta caaaatcata atatgacata
    83941 acacactatc ccttttagac aatattccaa ttagccttat taattcaaaa ctattgtatt
    84001 agtaattata acagatgtat aatagaaaag caatgataga tattatcaat taagcgaatt
    84061 tatatctaaa agggatatta aagaaaggag atatgcttat gaagatttac aaaaaactat
    84121 ttgcttatgt ccaagataag aaatatcttg gggttttggc cataattttt tctgctatat
    84181 ctgctgcact tacagtatat ggatattatt taatctacaa atttctagat aagttaataa
    84241 ttaattcaaa cttatccggt gcagagagta tagcattaaa atctgttatt acactaacaa
    84301 gtggagcgat attttatttt gtctcaggaa tgttttcaca tatcttggga tttaggcttg
    84361 aaacaaattt aagaaaaagg ggaatcgatg gtctggaaaa agcaagtttt aggttctttg
    84421 acttaaatcc atctggtcaa ataagaaaga tcatagatga taatgcagca caaactcatc
    84481 aggtggtagc tcacatgatt ccagatagct ctcaggcaat agtcacacct atacttgtcc
    84541 ttgtactagg ctttatagta agtataaggg ttggtataac tttgcttgct cttactataa
    84601 ttggcggctt aattttaggg gcgatgatgg gcgagcaaga atttatgaag atataccaag
    84661 aagctctatc taaactaagt gctgagactg tcgagtacgt tagaggaatg caggttgtaa
    84721 aaatatttaa agcaaatgta gagtctttta aaagctttta taaggcgata aaagattact
    84781 caaagtatgc ttatgattat tccctatctt gtaaaaggcc ttatgttttg tatcaatggt
    84841 tattttttgg actgattgca attttaatta ttcctatagt ttattttatg actagcttag
    84901 ctagcgcaaa ggtgatttta cttgagctta tcatgatttt atttttatca ggagttctct
    84961 ttgtttcatt catgagaatg atgtggtact ccatgtatat ttctcaagga aattatgcag
    85021 tagatacttt agaggcgctt tacgaagata tgcaaaaaga caaattagtg catggtaatg
    85081 tcaataattt taaaaactat aatatagaat ttgagaatgt tagctttgct tataatgata
    85141 aagctgtcat tgaaaattta tcctttaatt tagaagaagg aaagtcctac gcacttgtcg
    85201 gttcatctgg atcaggcaaa tcaacagtag caaaacttat atcaggtttt tacaatgtta
    85261 ataaaggaag cataaagata ggcgggatag caataagtga atattctgac gaagccttaa
    85321 ttaaagccat ttcctttgtt tttcaagatt caaaattatt caagaagagc atttatgata
    85381 atgtagcttt agctaataaa gatgcgacga aagatgacgt tatgagagcc ttaaaattag
    85441 caggatgcga tttaatatta gacaaattcc cagaaagaga aaatacaatc atagggtcaa
    85501 aaggtgttta tttatccggt ggagaaaaac aaagaattgc aattgctaga gcaattttaa
    85561 aggattccaa aattattatt atggatgaag catcagcatc tattgaccca gataacgagt
    85621 ttgagttgca aaaagctttc aaaaatctta tgaaggataa aacagttatc atgattgcac
    85681 acaggctatc tacaattaaa gaccttgatg aaattattgt tatggatagt ggaaaaatta
    85741 tagaaagagg gtctgacaaa gaattaatgt caaaagatac aaggtataag agcctgcaag
    85801 agatgtttaa cagtgcgaat gaatggaggg tttcaaatga aagagtttta taaaaaaaga
    85861 tttgctctta cagatagagg agcaagaaat ttaagtaaag caacactggc ttcatttttc
    85921 gtttattgta taaacatgcc tcctgccata ttacttatga tttttgctca ggaagttttg
    85981 gaaaatatgg gcaaaagcaa tggcttttat atagtattct cagttttgac tttgatagca
    86041 atgtatattt tgctttctat cgaatacgat aaattatata acacaaccta tcaagaaagt
    86101 gcagatttaa gaataaggac agcggagaat ttatcaaaat tacctctatc ttacttttct
    86161 aaacatgaca tttccgacat ttcacaaaca atcatggctg atattgaagg catagagcat
    86221 gcaatgagcc actcaatacc aaaggtgggc ggcatggtac tgtttttccc attaatatct
    86281 gtaatgatgc tagcgggcaa tgtcaagatg ggtttagctg taattattcc atctatttta
    86341 agctttatat ttataccttt atctaaaaaa tatcaggtta agggacagaa tagatattat
    86401 gatgtcttaa gaaaaaactc agaaagcttt caagaaaata tcgaaatgca aatggagatt
    86461 aaagcatata atttatcgaa ggatattaaa gatgacttat ataaaaaaat ggaagatagt
    86521 gagagagtac acttaaaggc ggaagtaact acaattttaa ctttgtctat atcttcaata
    86581 tttagcttta tatctcttgc tgttgtgata tttgtcggcg taaatctaat tattaataaa
    86641 gagataaatt ctctctacct tataggatat ttactagctg ctatgaagat aaaagactct
    86701 ttagatgcat ctaaagaggg cttgatggaa atattttatt tatcgcccaa aatagaaaga
    86761 ttaaaagaaa ttcaaaatca agatttacaa gaaggcgatg actatagttt aaaaaaattt
    86821 gatattgatc taaaagatgt tgagtttgcc tacaataaag acgcaaaagt tttaaatggt
    86881 gtaagtttta aagctaagca gggagaggtc actgctttgg taggtgcaag tggctgcggt
    86941 aaaacaacta tcttgaaact tatatcaaga ctttatgatt atgacaaggg acaaatctta
    87001 atcgatggca aagatataaa agaaatatca acagaatctc tttttaataa ggtctctata
    87061 gttttccaag atgtggttct ctttaatcaa agcattatgg aaaatattag aatcggaaag
    87121 caagatgcaa gtgacgaaga ggttaaaaga gcagcaaaac ttgcaaattg cacagatttt
    87181 atagaaaaaa tggataaagg tttcgataca gttattggtg agaacggagc tgagctatca
    87241 ggaggagaaa gacaaagatt atcaatagcc agagccttct taaaagatgc gccgatattg
    87301 atcttagatg agataacagc aagccttgat gttaacaacg agaaaaagat tcaagagtct
    87361 ttaaataatt tagttaaaga taaaactgtt gtaatcattt cacatagaat gaaatccata
    87421 gaaaatgcag acaagatagt agttcttcaa aacggaagag tagaaagcga aggtaagcat
    87481 gaagagcttt tacaaaaatc aaaaatttac aaaaatttaa tagaaaagac aaaaatggca
    87541 gaagaattta tttattagga ggactacaat ggataataaa aaattaaaag taaaagattt
    87601 agtaagcatc ggtgtttttg gcgtaattta ttttgccttc atgtttggag ttggtatgat
    87661 gggcttgatt ccaatattgt tcttaatata cccgacagta ttagccatag ttgcaggaac
    87721 tgttgttatg ttatttatgg ctaaggttca aaagccatgg gcactattta tatttggtat
    87781 gatatcacca cttgtgatgt ttgcagctgg tcatacctac gtagttgtgg ttttatcact
    87841 tatagtaatg ataatagcag aattaattag aaagattggt aattataatt catttaaata
    87901 caatatgctt tcttatgcaa tcttcagcac atggatatgt agctctttaa tgcaaatgct
    87961 tttagcaaaa gaaaaatata tggagtggtc tttgatgacg atgggaaaag attatgttga
    88021 tgtattagaa aagttaataa cttatcctca tatggcttta gtagccttag gtgctttctt
    88081 aggaggaatt cttggagcat atataggcaa ggctctattg aaaaaacact ttgaaaaagc
    88141 aggcattgta taatgcctac tttttcttca aatgctccct ttaatcccaa tccgatctct
    88201 aagatattag tcatatttat cacaggctta actgttatgc atagcataaa catccgtttt
    88261 gagctggcaa ttgtttgtct tattggtatt ttgctttatt tgaatggata caaaaaaaca
    88321 cttttcaaat ggattatatt gtgtgggata ctttactcct tgcctaattt tatggtgcta
    88381 tctgaattaa accctatagt taagatgttt ttgagtatac ctattgttat tagaatgttt
    88441 attttaccat ttatggcagc aagctttatg ataaagacct cggatgtagg cgcaataatt
    88501 tcatcgatgg ataagcttaa gatttcaaag aatgtatcca tacctattgc ggttatgttt
    88561 agattcttcc catcttttaa ggaggagaag aaaaacatca aaatggctat gagagtaaga
    88621 gggataaatt ttaaaaaccc agtcaaatat cttgaatatg tttctgtgcc actactcatt
    88681 atatcatcta atatatcaga tgacattgca aaagcggcag aaacaaaggc aatagaaaat
    88741 ccaattgcca agaccagata cattcgcgta aagatacagc taattgattt tgtttatgtt
    88801 ttagcggttg ctggacttat tgtgggaggc ttaatatggt tgaaataaaa aatttaagtc
    88861 ttgattatgg tgaagagcat atattagatg atatatcact atccatagcc gagggagagt
    88921 gcgtgctatt tacaggaaaa agtggaaatg gtaagtcatc tttaataaat tcaatcaatg
    88981 gactagctgt aaggtatgat aacgcaaaga caaagggcaa aataattatt gatggtaaga
    89041 atataaaaaa tttggaactt tatcaaatct caatgcttgt ttcaactgtt tttcaaaatc
    89101 ctaagacata tttttttaat gtcaatacga cattagaatt attattttat ttggaaaata
    89161 tcggtcttgc aagagaagag atggacaggc gtttgaagga tatgcttgag atattcccga
    89221 taaaaaatct tttgaacaga aatatattta atctatccgg cggtgaaaaa caaattcttt
    89281 gcattgcagc ttcttatata gcaggtacaa agattatagt tatggatgag ccttcatcga
    89341 atttagatat taaaagcata agtgttttgg caaagatgct aaagatatta aaagagaaag
    89401 gcataagcat aattgttgca gagcatagaa tttattattt gatggacata gttgaccgtg
    89461 tatttttaat agataaagga aagcttaaaa aaacttatac tagaagtgaa tttttaaagc
    89521 tagataaaaa tgaattaaat gctttaagtt taagagataa agaattaagt aaattaaaag
    89581 ttccttattt aaaagaaggt ggagagtatc agataaaaaa tcttagctac aaatttactg
    89641 atgatgagtg tttaagctta aaagatattt cgttcaagct tgggaaaatt tatggcataa
    89701 taggatccaa cggacgagga aaatcaacgc ttttaagatg tttaataggt cttgagaaaa
    89761 aatcaaaaga agaaatttat tttaagggag agaagctatc taaaaaagaa agactcaaaa
    89821 actcttcact tgttatgcaa gatgtaaatc atcaattatt cacagatgaa gtattcaacg
    89881 agcttagatt aggagtaaag aattttgatg aagaaaaggc gaaaatcatc ttaaaagatt
    89941 taggcctgga cgaatttatt gaaaggcatc cgatgagttt atcaggaggg caaaagcaaa
    90001 ggcttgcaat agcatctgtt atgtgcaaga attctccatt tgtctttttt gacgaacctt
    90061 caagtggtat ggattattcc aatatgataa aaatatctga actgattaat aagtataaaa
    90121 ccatggataa aataattttt attgtttccc atgatataga atttttaaat gaagtggcag
    90181 atgaaatttt tgaattgtaa aatagagtct gttaaacatg tctatagaac tagtaaattg
    90241 tctaaaaatt taaaagatac taacacatat tgatatttat tagaaaatta acttcaggat
    90301 ttttacagta tttataaact ttataatatg tatttatagt attaataatt tccatatctt
    90361 tagggaaatt ctttatttac ttaccataat taaagagatg agagataaat atcggcagtc
    90421 ttcggactgc ctttattttt ttacttaatt taatgcagta aatcatacga ttgaaaggaa
    90481 tctgcgttat atgctataat taggtggtta atctatacat ttagaaaggt aaaatataga
    90541 attggagaat gatatgggat tttcatataa taaattgtaa ccgtccaata acgaagtcta
    90601 ttgaaaaatc tccagactag agaactcacg gatagttcct aatctggaga tttcttattt
    90661 gcacttttct tgtacaactt tagtccacga taaataggcc tctaaaacct ctttgtttac
    90721 gagagtttcc tcgtttggaa gacattctag aagataggat agatatttct cactatttag
    90781 ttgatgacgt ttagctgttt ccaataagct cataataata gctcttgctt tagctccttc
    90841 aaaaactttg agaaaacaac caccctcgct tttttaaact gagcttaggc taaaagagtc
    90901 cactggactc ttttactccg tcccataacc aatgatttaa tggcgcgttc agctagatta
    90961 ttggaaagga ccagatgtcc gtcttttaaa atggtcttaa aggtttcttc atacttgagg
    91021 ctgtattcaa ttgcccttcc tagttttgaa cccgataaaa ctgactgacg acggcaccaa
    91081 gcaaagaagt cttccagtag gggttggaga tgttcttgac gtttctgtag tcgttcatca
    91141 gctggcaaag cctcccagtc tctttccaag gaaaataact gatcacaata agctaaacct
    91201 ttagctccta aggatgattt atctgcttgc ttggggggca cttcaaaaaa cttccttctc
    91261 acatgcgccc aacatccaac aagtgcagct tcttccagtt gacgataagc ttctagctgt
    91321 tcgcagttta ccaagcttag cgtcgcctta ctcctaaact ttggactgct atcgcatagg
    91381 cagaactaga ggactaaagt cctaagttac tgccgcaaca tgtcacaatg aacatagcca
    91441 gaataatctc ctaggaattc ttgtactact aaaccactcc gacgctgatc atggtggtac
    91501 agcgtgattg cttgattctc agctttccca gacaaaaaag tccaatagta agtcaactga
    91561 ctatcactct ctagaacccg ataagaggtt tcatccgcat gaagtaaggg cttgagtcaa
    91621 tagtctcgtt ataaaggggc tttaggaata ggagctttca cgattttatc actcggattt
    91681 ttatcactgc atgcttggca tttgtaagcg tgttggatat gatctatgcg ttttaattgc
    91741 gcaggaataa agaccaattc ttgtccttga agactccctc caatctcttt tagatctccc
    91801 tgacaatcag ggcaaatcct ctcttctact tgatgatgaa cttcttctga atcaaattgg
    91861 gcaagaagag cttggcgttt ccctttagat ttcttacgtt tgtaggtaat ttcctctgtt
    91921 tcaactggga acatctccat cttcctcaga tggagactct tcctcaaaaa ggttgagttg
    91981 tccagagggg caaacacttt tctcagagga ttttccatag agcttttgag tcagataagc
    92041 cacttgttca cgaagaaggg caagttcatt ggtgagacta tcaattgtag cactctgttg
    92101 ttgaatgatt ttcaatcttc ttccatgagc ttccctctct gttttctaac tttattata
//
LOCUS       DBEROT010000003        90048 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.03, whole genome shotgun sequence.
ACCESSION   DBEROT010000003 DBEROT010000000
VERSION     DBEROT010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 90048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.03"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            277..933
                     /locus_tag="ACL8CG_000206"
     CDS             277..933
                     /locus_tag="ACL8CG_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGS1342874.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            923..1246
                     /locus_tag="ACL8CG_000207"
     CDS             923..1246
                     /locus_tag="ACL8CG_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGS1342875.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMILFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1350..2180
                     /locus_tag="ACL8CG_000208"
     CDS             1350..2180
                     /locus_tag="ACL8CG_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1342876.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2334..3188
                     /locus_tag="ACL8CG_000209"
     CDS             2334..3188
                     /locus_tag="ACL8CG_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS1342877.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3288..4661
                     /locus_tag="ACL8CG_000210"
     CDS             3288..4661
                     /locus_tag="ACL8CG_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGS1342878.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4654..5715
                     /locus_tag="ACL8CG_000211"
     CDS             4654..5715
                     /locus_tag="ACL8CG_000211"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGS1342879.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5717..6409
                     /locus_tag="ACL8CG_000212"
     CDS             5717..6409
                     /locus_tag="ACL8CG_000212"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGS1342880.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6439..7008)
                     /locus_tag="ACL8CG_000213"
     CDS             complement(6439..7008)
                     /locus_tag="ACL8CG_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS1342881.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7143..7757
                     /locus_tag="ACL8CG_000214"
     CDS             7143..7757
                     /locus_tag="ACL8CG_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS1342882.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLVGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7735..9405
                     /locus_tag="ACL8CG_000215"
     CDS             7735..9405
                     /locus_tag="ACL8CG_000215"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1342883.1"
                     /translation="MKNWRQNRMKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDRESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9417..10703
                     /locus_tag="ACL8CG_000216"
     CDS             9417..10703
                     /locus_tag="ACL8CG_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1342884.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10755..11288
                     /locus_tag="ACL8CG_000217"
     CDS             10755..11288
                     /locus_tag="ACL8CG_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1342885.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11366..11836
                     /gene="nrdI"
                     /locus_tag="ACL8CG_000218"
     CDS             11366..11836
                     /gene="nrdI"
                     /locus_tag="ACL8CG_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGS1342886.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12129..13391)
                     /locus_tag="ACL8CG_000219"
     CDS             complement(12129..13391)
                     /locus_tag="ACL8CG_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGS1342887.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDAVFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13701..14159)
                     /locus_tag="ACL8CG_000220"
     CDS             complement(13701..14159)
                     /locus_tag="ACL8CG_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGS1342888.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14156..14596)
                     /locus_tag="ACL8CG_000221"
     CDS             complement(14156..14596)
                     /locus_tag="ACL8CG_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1342889.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14952..16901
                     /gene="mutL"
                     /locus_tag="ACL8CG_000222"
     CDS             14952..16901
                     /gene="mutL"
                     /locus_tag="ACL8CG_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGS1342890.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17226..17693)
                     /gene="ribE"
                     /locus_tag="ACL8CG_000223"
     CDS             complement(17226..17693)
                     /gene="ribE"
                     /locus_tag="ACL8CG_000223"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGS1342891.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17694..18899)
                     /locus_tag="ACL8CG_000224"
     CDS             complement(17694..18899)
                     /locus_tag="ACL8CG_000224"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGS1342892.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGMGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18919..19554)
                     /gene="ribE"
                     /locus_tag="ACL8CG_000225"
     CDS             complement(18919..19554)
                     /gene="ribE"
                     /locus_tag="ACL8CG_000225"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGS1342893.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19539..20639)
                     /gene="ribD"
                     /locus_tag="ACL8CG_000226"
     CDS             complement(19539..20639)
                     /gene="ribD"
                     /locus_tag="ACL8CG_000226"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGS1342894.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVQQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20773..20887)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21044..21637
                     /gene="ruvA"
                     /locus_tag="ACL8CG_000227"
     CDS             21044..21637
                     /gene="ruvA"
                     /locus_tag="ACL8CG_000227"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGS1342895.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21647..22210
                     /locus_tag="ACL8CG_000228"
     CDS             21647..22210
                     /locus_tag="ACL8CG_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGS1342896.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22207..22884
                     /locus_tag="ACL8CG_000229"
     CDS             22207..22884
                     /locus_tag="ACL8CG_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1342897.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(23039..24070)
                     /locus_tag="ACL8CG_000230"
     CDS             complement(23039..24070)
                     /locus_tag="ACL8CG_000230"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGS1342898.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCPKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(24325..25008)
                     /locus_tag="ACL8CG_000231"
     CDS             complement(24325..25008)
                     /locus_tag="ACL8CG_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGS1342899.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(25020..25964)
                     /locus_tag="ACL8CG_000232"
     CDS             complement(25020..25964)
                     /locus_tag="ACL8CG_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS1342900.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26096..28927
                     /gene="uvrA"
                     /locus_tag="ACL8CG_000233"
     CDS             26096..28927
                     /gene="uvrA"
                     /locus_tag="ACL8CG_000233"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGS1342901.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKADVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28920..29981
                     /locus_tag="ACL8CG_000234"
     CDS             28920..29981
                     /locus_tag="ACL8CG_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS1342902.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30113..30511
                     /gene="spx"
                     /locus_tag="ACL8CG_000235"
     CDS             30113..30511
                     /gene="spx"
                     /locus_tag="ACL8CG_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGS1342903.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30577..31146
                     /locus_tag="ACL8CG_000236"
     CDS             30577..31146
                     /locus_tag="ACL8CG_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGS1342904.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKIYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31233..31499
                     /locus_tag="ACL8CG_000237"
     CDS             31233..31499
                     /locus_tag="ACL8CG_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGS1342905.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31503..31922
                     /gene="ruvX"
                     /locus_tag="ACL8CG_000238"
     CDS             31503..31922
                     /gene="ruvX"
                     /locus_tag="ACL8CG_000238"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGS1342906.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31938..32243
                     /locus_tag="ACL8CG_000239"
     CDS             31938..32243
                     /locus_tag="ACL8CG_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGS1342907.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32498..33748
                     /locus_tag="ACL8CG_000240"
     CDS             32498..33748
                     /locus_tag="ACL8CG_000240"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS1342908.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSHREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33832..34290
                     /locus_tag="ACL8CG_000241"
     CDS             33832..34290
                     /locus_tag="ACL8CG_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGS1342909.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQQVQQPAQQ
                     NTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESD
                     GDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34436..35968
                     /gene="cls"
                     /locus_tag="ACL8CG_000242"
     CDS             34436..35968
                     /gene="cls"
                     /locus_tag="ACL8CG_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGS1342910.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36226..37764
                     /locus_tag="ACL8CG_000243"
     CDS             36226..37764
                     /locus_tag="ACL8CG_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGS1342911.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37884..40091
                     /gene="nrdD"
                     /locus_tag="ACL8CG_000244"
     CDS             37884..40091
                     /gene="nrdD"
                     /locus_tag="ACL8CG_000244"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGS1342912.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40103..40243
                     /locus_tag="ACL8CG_000245"
     CDS             40103..40243
                     /locus_tag="ACL8CG_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342913.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKYSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40287..40793
                     /locus_tag="ACL8CG_000246"
     CDS             40287..40793
                     /locus_tag="ACL8CG_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1342914.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            40786..41376
                     /gene="nrdG"
                     /locus_tag="ACL8CG_000247"
     CDS             40786..41376
                     /gene="nrdG"
                     /locus_tag="ACL8CG_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGS1342915.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41373..41990
                     /locus_tag="ACL8CG_000248"
     CDS             41373..41990
                     /locus_tag="ACL8CG_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS1342916.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTLAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRFARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42245..42553
                     /gene="rpsJ"
                     /locus_tag="ACL8CG_000249"
     CDS             42245..42553
                     /gene="rpsJ"
                     /locus_tag="ACL8CG_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGS1342917.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42769..43395
                     /gene="rplC"
                     /locus_tag="ACL8CG_000250"
     CDS             42769..43395
                     /gene="rplC"
                     /locus_tag="ACL8CG_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGS1342918.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43420..44043
                     /gene="rplD"
                     /locus_tag="ACL8CG_000251"
     CDS             43420..44043
                     /gene="rplD"
                     /locus_tag="ACL8CG_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGS1342919.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44043..44339
                     /locus_tag="ACL8CG_000252"
     CDS             44043..44339
                     /locus_tag="ACL8CG_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGS1342920.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44357..45190
                     /gene="rplB"
                     /locus_tag="ACL8CG_000253"
     CDS             44357..45190
                     /gene="rplB"
                     /locus_tag="ACL8CG_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGS1342921.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGAVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45294..45575
                     /gene="rpsS"
                     /locus_tag="ACL8CG_000254"
     CDS             45294..45575
                     /gene="rpsS"
                     /locus_tag="ACL8CG_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGS1342922.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45587..45931
                     /gene="rplV"
                     /locus_tag="ACL8CG_000255"
     CDS             45587..45931
                     /gene="rplV"
                     /locus_tag="ACL8CG_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGS1342923.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45944..46597
                     /gene="rpsC"
                     /locus_tag="ACL8CG_000256"
     CDS             45944..46597
                     /gene="rpsC"
                     /locus_tag="ACL8CG_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGS1342924.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46601..47014
                     /gene="rplP"
                     /locus_tag="ACL8CG_000257"
     CDS             46601..47014
                     /gene="rplP"
                     /locus_tag="ACL8CG_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGS1342925.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            47024..47230
                     /gene="rpmC"
                     /locus_tag="ACL8CG_000258"
     CDS             47024..47230
                     /gene="rpmC"
                     /locus_tag="ACL8CG_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGS1342926.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47255..47515
                     /gene="rpsQ"
                     /locus_tag="ACL8CG_000259"
     CDS             47255..47515
                     /gene="rpsQ"
                     /locus_tag="ACL8CG_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGS1342927.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47541..47909
                     /gene="rplN"
                     /locus_tag="ACL8CG_000260"
     CDS             47541..47909
                     /gene="rplN"
                     /locus_tag="ACL8CG_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGS1342928.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47987..48292
                     /gene="rplX"
                     /locus_tag="ACL8CG_000261"
     CDS             47987..48292
                     /gene="rplX"
                     /locus_tag="ACL8CG_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGS1342929.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48316..48858
                     /gene="rplE"
                     /locus_tag="ACL8CG_000262"
     CDS             48316..48858
                     /gene="rplE"
                     /locus_tag="ACL8CG_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGS1342930.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48876..49145
                     /gene="rpsN"
                     /locus_tag="ACL8CG_000263"
     CDS             48876..49145
                     /gene="rpsN"
                     /locus_tag="ACL8CG_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGS1342931.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49430..49828
                     /gene="rpsH"
                     /locus_tag="ACL8CG_000264"
     CDS             49430..49828
                     /gene="rpsH"
                     /locus_tag="ACL8CG_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGS1342932.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGSNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            50020..50556
                     /gene="rplF"
                     /locus_tag="ACL8CG_000265"
     CDS             50020..50556
                     /gene="rplF"
                     /locus_tag="ACL8CG_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGS1342933.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50640..50996
                     /gene="rplR"
                     /locus_tag="ACL8CG_000266"
     CDS             50640..50996
                     /gene="rplR"
                     /locus_tag="ACL8CG_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGS1342934.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            51014..51508
                     /gene="rpsE"
                     /locus_tag="ACL8CG_000267"
     CDS             51014..51508
                     /gene="rpsE"
                     /locus_tag="ACL8CG_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGS1342935.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51522..51704
                     /gene="rpmD"
                     /locus_tag="ACL8CG_000268"
     CDS             51522..51704
                     /gene="rpmD"
                     /locus_tag="ACL8CG_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGS1342936.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51849..52289
                     /gene="rplO"
                     /locus_tag="ACL8CG_000269"
     CDS             51849..52289
                     /gene="rplO"
                     /locus_tag="ACL8CG_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGS1342937.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52302..53612
                     /gene="secY"
                     /locus_tag="ACL8CG_000270"
     CDS             52302..53612
                     /gene="secY"
                     /locus_tag="ACL8CG_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGS1342938.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53763..54401
                     /locus_tag="ACL8CG_000271"
     CDS             53763..54401
                     /locus_tag="ACL8CG_000271"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGS1342939.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54518..54736
                     /gene="infA"
                     /locus_tag="ACL8CG_000272"
     CDS             54518..54736
                     /gene="infA"
                     /locus_tag="ACL8CG_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGS1342940.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54761..54877
                     /gene="rpmJ"
                     /locus_tag="ACL8CG_000273"
     CDS             54761..54877
                     /gene="rpmJ"
                     /locus_tag="ACL8CG_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGS1342941.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54895..55260
                     /gene="rpsM"
                     /locus_tag="ACL8CG_000274"
     CDS             54895..55260
                     /gene="rpsM"
                     /locus_tag="ACL8CG_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGS1342942.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55278..55661
                     /gene="rpsK"
                     /locus_tag="ACL8CG_000275"
     CDS             55278..55661
                     /gene="rpsK"
                     /locus_tag="ACL8CG_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGS1342943.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55704..56639
                     /locus_tag="ACL8CG_000276"
     CDS             55704..56639
                     /locus_tag="ACL8CG_000276"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGS1342944.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56651..57037
                     /gene="rplQ"
                     /locus_tag="ACL8CG_000277"
     CDS             56651..57037
                     /gene="rplQ"
                     /locus_tag="ACL8CG_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGS1342945.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57302..57568
                     /locus_tag="ACL8CG_000278"
     CDS             57302..57568
                     /locus_tag="ACL8CG_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGS1342946.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57578..58915
                     /locus_tag="ACL8CG_000279"
     CDS             57578..58915
                     /locus_tag="ACL8CG_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGS1342947.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59159..59851
                     /locus_tag="ACL8CG_000280"
     CDS             59159..59851
                     /locus_tag="ACL8CG_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1342948.1"
                     /translation="MVKVRLYLARHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59954..61606)
                     /locus_tag="ACL8CG_000281"
                     /pseudo
     CDS             complement(59954..61606)
                     /locus_tag="ACL8CG_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61596..62687)
                     /locus_tag="ACL8CG_000282"
                     /pseudo
     CDS             complement(61596..62687)
                     /locus_tag="ACL8CG_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62700..63821)
                     /locus_tag="ACL8CG_000283"
                     /pseudo
     CDS             complement(62700..63821)
                     /locus_tag="ACL8CG_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(64038..64262)
                     /locus_tag="ACL8CG_000284"
                     /pseudo
     CDS             complement(64038..64262)
                     /locus_tag="ACL8CG_000284"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(64310..65086)
                     /locus_tag="ACL8CG_000285"
     CDS             complement(64310..65086)
                     /locus_tag="ACL8CG_000285"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGS1342949.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            65208..65954
                     /locus_tag="ACL8CG_000286"
     CDS             65208..65954
                     /locus_tag="ACL8CG_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1342950.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65967..66947
                     /locus_tag="ACL8CG_000287"
     CDS             65967..66947
                     /locus_tag="ACL8CG_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGS1342951.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67142..67462
                     /locus_tag="ACL8CG_000288"
     CDS             67142..67462
                     /locus_tag="ACL8CG_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1342952.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67508..67816
                     /locus_tag="ACL8CG_000289"
     CDS             67508..67816
                     /locus_tag="ACL8CG_000289"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1342953.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67833..69131
                     /locus_tag="ACL8CG_000290"
     CDS             67833..69131
                     /locus_tag="ACL8CG_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1342954.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            69282..71720
                     /locus_tag="ACL8CG_000291"
     CDS             69282..71720
                     /locus_tag="ACL8CG_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGS1342955.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71739..72407
                     /locus_tag="ACL8CG_000292"
     CDS             71739..72407
                     /locus_tag="ACL8CG_000292"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGS1342956.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            72425..73513
                     /locus_tag="ACL8CG_000293"
     CDS             72425..73513
                     /locus_tag="ACL8CG_000293"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGS1342957.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            73968..76469
                     /gene="leuS"
                     /locus_tag="ACL8CG_000294"
     CDS             73968..76469
                     /gene="leuS"
                     /locus_tag="ACL8CG_000294"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGS1342958.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTS
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIVAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFVQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVIAVPNKLVNIVVK"
     gene            76664..77359
                     /locus_tag="ACL8CG_000295"
     CDS             76664..77359
                     /locus_tag="ACL8CG_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1342959.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQESVADMEELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPKLRGTRIGTEAQYLLARYVFEELNYRRYEWKCDSL
                     NLPSRRAAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKARLEAWLTPENF
                     DKTGQQYKSLREL"
     gene            77371..77787
                     /locus_tag="ACL8CG_000296"
     CDS             77371..77787
                     /locus_tag="ACL8CG_000296"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1342960.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YVALDGDAVVGLIRLVGDGFSSVFVQDLIVLPNYQRQGIGSLLMKEALKDYKDAYQVQ
                     LVTEETEKNVRFYRSMGFEALSTYDCIGMTWVNREK"
     gene            complement(78624..78716)
                     /locus_tag="ACL8CG_000297"
     CDS             complement(78624..78716)
                     /locus_tag="ACL8CG_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGS1342961.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            78850..79848
                     /gene="ruvB"
                     /locus_tag="ACL8CG_000298"
     CDS             78850..79848
                     /gene="ruvB"
                     /locus_tag="ACL8CG_000298"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGS1342962.1"
                     /translation="MGRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            79829..80401
                     /locus_tag="ACL8CG_000299"
                     /pseudo
     CDS             79829..80401
                     /locus_tag="ACL8CG_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            80632..81390
                     /locus_tag="ACL8CG_000300"
     CDS             80632..81390
                     /locus_tag="ACL8CG_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGS1342963.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            81399..82202
                     /locus_tag="ACL8CG_000301"
     CDS             81399..82202
                     /locus_tag="ACL8CG_000301"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGS1342964.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            82224..83483
                     /gene="rseP"
                     /locus_tag="ACL8CG_000302"
     CDS             82224..83483
                     /gene="rseP"
                     /locus_tag="ACL8CG_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGS1342965.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            83496..85349
                     /locus_tag="ACL8CG_000303"
     CDS             83496..85349
                     /locus_tag="ACL8CG_000303"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGS1342966.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            85448..86827
                     /gene="bglA"
                     /locus_tag="ACL8CG_000304"
     CDS             85448..86827
                     /gene="bglA"
                     /locus_tag="ACL8CG_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS1342967.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYDNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            87019..88827
                     /gene="glmS"
                     /locus_tag="ACL8CG_000305"
     CDS             87019..88827
                     /gene="glmS"
                     /locus_tag="ACL8CG_000305"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGS1342968.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            88947..89996
                     /locus_tag="ACL8CG_000306"
     CDS             88947..89996
                     /locus_tag="ACL8CG_000306"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGS1342969.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKIGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
BASE COUNT        27052 a        16491 c        19919 g        26586 t
ORIGIN      
        1 tcatcttatt tcaatctgct atataatagt ccatgctgtg gctggattct tttcagccta
       61 cttatactct tcgaaactct cttcaaacca cgtcagcttc accttgccgt atatgtgtta
      121 ctgacttcgt cagttctatc cacaacctca aaacggtgtt ttgagcaacc tgcggctagt
      181 ttcctagttt gctctttgat tttcattgag tattattaaa acaatatgag gagaaagatg
      241 aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct tggctatgtc
      301 agtatcggcc tggcctgtgg gactatcggt gctccctatg tgacacctgt tgagatgggc
      361 ttgatgagtc tctttgttta tgctgggagt gcccagtttg ccatgttggc actgattgtg
      421 gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt gcgtctcttt
      481 ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta caatatcggt
      541 atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt ggcccataca
      601 gacaaggtaa atcctatgtg gatgcacggg aacaatctca acagctatgt ggcttggttt
      661 gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga aatctttggc
      721 ttggattttg ccctggttgg gatgtttatt ggtatttttg cttcgcaatt tcagattatg
      781 caaagacgga ttcctgtccg caatctgctc attatcctag cagttgttgc ggtgtccttc
      841 tttttgctct tgacagtggt gtctcagtca ctagctgttc tgtttgcgac gctacttggt
      901 tgtagcatgg gggtggtttt agatggtcag taagtatctt ttattagcag ttattttctc
      961 tggtcttgtg acctggattc cccgtatgat tctcttcatc ttggtcaagc ataagggcct
     1021 gcctgcgatt gttgagcgtt ttttgaagtt tttgcctgtt tccattatct ttgccttgat
     1081 tctttcaagc gtagtgacag gtaaggttgg gagccttcct caaattaaat ggctagactt
     1141 cttagccgtc tttccaacag cttgggtagc ctttcgctac cgcaatctag tcggaacagt
     1201 tctctttgga gtggtcttga ttgccatctt gcgtttggtc ttttaaatta cccataaaaa
     1261 aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc tgttaagatt
     1321 ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg
     1381 cagcccttgc tcttgttgct gcaggtgtgc ttgcggcttg ctcaggtggt gctaagaaag
     1441 aaggacaagc agctagcaag aaagaaatca tcgttgcaac caatggatca ccaaggccat
     1501 ttatctatga agaaaatggc gaattgactg gttacgagat tgaagtcgtt cgcgctatct
     1561 ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca ggtgtctttg
     1621 ctggtcttga cgctgaccgt tacaatatgg ctgtcaacaa tcttagctac actaaagaac
     1681 gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc cttgtcgtga
     1741 agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg acggaagtcg
     1801 ttcaagccac tacatcagct aagcagttag aagcatacaa cgctgaacac acggacaacc
     1861 caactatcct taactatact aaggcagatt tccaacaaat catggtacgt ttgagcgatg
     1921 gacaatttga ctataagatt tttgataaaa tcggtgttga aacagtgatc aagaaccaag
     1981 gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac gtttacccac
     2041 ttcttgctca gggtcaagat gagttgaaat cgtttgtaga caaacgcatc aaagaacttt
     2101 ataaagatgg aactcttgaa aaattgtcta aacaattctt cggagacact tatctaccgg
     2161 cagaagctga tattaaataa tttcttgaaa tcatccattc tgagtaagat gggtggtttc
     2221 tcagttttta gggatatagt tttaaactat atatctgact atctaataac aatttgtgaa
     2281 atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga atcatgaaaa
     2341 tcaaaaaatg gcttggtcta gcagcccttg ctacagtcgc aggtttggct cttgcagctt
     2401 gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca actgttaacc
     2461 gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa aaagacggaa
     2521 ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca actgctgatg
     2581 gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg aacaaagaaa
     2641 acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc ctttactcag
     2701 gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca aacggagaaa
     2761 tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt caatcagctg
     2821 gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac atcaaagaaa
     2881 atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt tcattgtcat
     2941 cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg gactacaaga
     3001 aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac atcattgttg
     3061 cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta atcgcagctt
     3121 accacacaga tgacgtgaaa aaagttatcg aagaatcatc agacggtttg gatcaaccag
     3181 tttggtaata agaaacaggg aggtgggaga gagaattcca cctcttgctt ttgtatagag
     3241 cacggagtgt aaagaagact attcgttcat agaaaggtag agagaatatg gtttttccta
     3301 gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agcccagcat tattttgagg
     3361 ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga ctcaaggaag
     3421 tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag attgatgaga
     3481 gctatacagc gccctttgtc atggcacatt tcaagagttc gcgtccagat gccaagacct
     3541 tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc tggacagagg
     3601 atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggagtt gatgacgaca
     3661 agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac catgatgatt
     3721 tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca acagacctag
     3781 ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg gtctgggaac
     3841 aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag gggattgtga
     3901 cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat ggtggtgttg
     3961 tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct gcggatggcc
     4021 gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga gaaatggcct
     4081 tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat ggattggagt
     4141 tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc gagccagcgc
     4201 ttaatatcga aggaatccag tctggttatc aaggtcaggg tgtgaagact attttacctg
     4261 cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg catgatgttc
     4321 tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa ttatactata
     4381 ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc aatgtgatcg
     4441 agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca gcggggacag
     4501 gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc ggtctaggaa
     4561 atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat tattacaccc
     4621 atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat caagttagat
     4681 cagatcgatg tgacttttca ccaaaagaag agaaccatca cagcggttaa ggatgtgacc
     4741 attcacatcc aagaagggga tatctacgga atcgttggat attctggagc agggaaatca
     4801 acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat taccattgac
     4861 gacgatgtga tttttgatgg taaggtcacc ttgacggcag agcagttgcg tcgtaaacgt
     4921 caagatatcg ggatgatttt ccagcatttt aacctgatga gtcaaaagac agcagaggag
     4981 aatgtagcct ttgcccttaa acactctgga ctcagcaagg aagaaaagaa ggctaaagta
     5041 gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc ttcacaatta
     5101 tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc
     5161 ttgatttcag acgagtcaac ttctgccctt gaccctaaga caaccaagca gattttggcc
     5221 ttgttgcaag atttgaacca aaaattaggc ttgactgttg tcttgattac gcatgaaatg
     5281 cagattgtca aagacattgc caaccgtgtt gcagttatgc aggatgggca tttgattgaa
     5341 gagggtagtg tgcttgaaat cttctcaaac cctaaacaac ctttgactca agactttatc
     5401 tcaacagcta caggtattga cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa
     5461 cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc aacagacgag
     5521 ccacttttga atgaattgta caagcattac caagtaatgg ctaatattct ctatgggaat
     5581 atcgaaattc tcgatggtac tcctgttgga gaattggtgg tggttttgtc aggtgaaaaa
     5641 gcagcgttgg caggtgccca agaagccatt cgtcaagcag gtgtacaact aaaagtattg
     5701 aagggagtac agtaagatgg aatcattgat tcaaacctat ttaccaaatg tctataaaat
     5761 gggttgggct ggtcaggcag gctggggaac ggctatctac ttaactcttt atatgacagt
     5821 tctttccttc attatcggag gcttcttggg gctagtggca ggtctctttc tcgtcttgac
     5881 agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca aaattacctc
     5941 aatttttcgt gcggttccct ttatcatcct cttggcaatc ttgtcaccac tttctcactt
     6001 gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt ttgcagtctt
     6061 tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg gtgtcattga
     6121 ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc tatcagaagg
     6181 tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg gggaaacagc
     6241 tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt atggatttaa
     6301 ccgctacaat cacgatgtga ccatcttggc aaccatcatt atcattttga ttatctttgc
     6361 aatccaattc ttgggagatt tcttgactaa gaaattgagc cataaataaa aaagagccgc
     6421 gtggctcttt ttaactgatc agattttctg tgcaaatttt ttactcaagg cttgtccaat
     6481 caaggcaccc actagggctc cgatgacaat acttgcgata aatagaagga cagttccagg
     6541 gtttggagcg accatgatgc ggtcgatata ttcttgggat tttcctcttg ccagaagagt
     6601 agccatatag gctttgggcg caatccacat aagcaagatt ggtcctgttg tactaaaggc
     6661 gaaaataatg aaagaaagga agttctttgt tttgtccttg tattttccta aatgagctac
     6721 ttcatctgct aggaggccac agataattcc aggaaggaag gaaccagcac cgtgtttagt
     6781 tcccaagaaa aagagggcaa tgacaaggcc gatagtggta atggctccaa agcgcggaac
     6841 ttttgcgact aggatcatat agacgctacc gccgacaagg gcagtaaagg caggcgcata
     6901 aaacatgttt ccagtttggt caaagagatt gcccaaaagg acaccaatcc ccatgcagag
     6961 gaagtaaaga actgcaaaaa gcagtgtagt taagatagat ttcttcatga attgtctcct
     7021 gataattttt tcacaattct cattgtacca cggtttggtg ggattgtaaa tggatactag
     7081 aagtttttga aaacgcttga aatatgatat aatggtttca tagttatttt taggggaata
     7141 tcatgggtag atttttagac tttgtcttta atcgtttctt tttagggatg attgcgacag
     7201 ccttcttttg gctattaact ttagtaggag ggattatcct tggtctagcg ccagctagtg
     7261 ccaccttgat gagcttatat gcagaacatg gttatagctt tcgggaatac agtttgaagg
     7321 aggcttggtc tctttacaag caaaattttg tctcaagcaa cctgattttc tatagctttt
     7381 taggtgtggg tctagttttg acctatggtt tgtatctctt ggtgcaattg cctcatcaga
     7441 ccattgttca tttgattgcg acccttttga atgtcctagt agttgccctg atctttttgg
     7501 cttatacagt atctttaaaa ttacaagttt attttgcctt gtcctatcga aatagtctca
     7561 aattatcctt gattggcatc tttatgagtc tagcagctgt ggccaagatt ctccttggga
     7621 ctgtgctact tgtagcaatt ggttactata tgcctgccct gctatttttt gtaggaattg
     7681 ggatgtggca tttctttatc agtgatatgt tggaacctgt ctatgaaatc atccatgaaa
     7741 aattggcgac aaaatagaat gaagcacttt tggctacata cgcttctaag aacctatagt
     7801 tcagtgatga tcattatcat tgcgagtttt gcaatcttac tctcttacgc tgactgggat
     7861 tcacgtgaaa aggaagccca gagagtagcc cagcgtgtaa ctgctagaac agtgagtgaa
     7921 attgaatatt accatagaga gtcaacccag atagctcagg ctttagttga aaaccaagct
     7981 cgtattgagg gaatctataa atactttagc cttagcatgc cagactattt ttactggcaa
     8041 ttagagcgga aagcttcgcc ttatatatca gtctctctgt atgaaaatgt tgatgacctc
     8101 tatgttcgaa atgattttgt aactggggtg gccattgctt ttcaagatta caaggaagtc
     8161 tatgtttcta ctaaagacaa acgtagtgga gaaaaaatca gggctgagga tttcaaacca
     8221 gcaggaaata gttttgccat tccggtgtca gatccagtgt cagatcaaga tttaggagtg
     8281 atttacatct ccttggatcc tgctgtttta taccatgcca ttgataatac tagaggtcat
     8341 actccgatgg cagtaacagt gacctcacct tttgatacgg agatttttca tattggtgag
     8401 acagttgata gggagagtga aaattggcta gttggcttaa cttctcatgg atatcaggtt
     8461 caggtggcag ttcctaaaaa ctttgtttta caaggaacag tgactagctc tgctttgatt
     8521 gtgggtttga gccttctctt tattgtcatt ctttatctga ctttgaggca gacttttgct
     8581 aattaccaaa agcaggtagt ggatttagta gaatccattc aagtcattgc tcaaggcgaa
     8641 gaggggcgtc ggattgacat ttccgagaaa gatcaggaat tactcctaat cgcggagacg
     8701 accaatgata tgttggatcg attggaaaag aatatccatg atatttacca gttagagctt
     8761 agtcaaaaag atgccaatat gcgagccttg caggcgcaaa tcaatcctca ttttatgtat
     8821 aatacgctgg agttcttgcg catgtatgca gttatgcaga gtcaagatga gttggcagat
     8881 atcatttatg aattcagtag tctcttgcgt aacaatattt ccgacgaaag agagaccctc
     8941 ctcaaacagg aattagaatt ttgccgtaaa tacagctatc tctgcatggt tcgctatccc
     9001 aagtccattg cctatggttt caagatagat ccagagttag agaatatgaa gattcccaag
     9061 tttaccttgc aaccgctggt agaaaactat ttcgcgcatg gtgttgacca caggcggaca
     9121 gataatgtga ttagcatcaa ggctcttaaa caggatggtt ttgtggaaat tttggtggtc
     9181 gataatggta gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa attaagtcag
     9241 agatattttg aacaccaagc cagctacagt gatcaaaggc agtctatcgg gattgtcaat
     9301 gtacacgagc gttttgtgct ctattttgga gaccgctatg ccattactat agagtctgca
     9361 gagcaagccg gtgttcagta tcgtattaca attcaagatg agtagaaagg gagaaaatgt
     9421 ataaagtatt attagtagat gatgagtaca tggtgacaga aggtctgaag cgtttgattc
     9481 cctttgataa gtgggatatg gaggttgtcg caacagccag tcatgccgat gaagctctag
     9541 aatatgttca ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg ccagacaaaa
     9601 cagggcttga tatgattcgg gagatgaaag agatcttacc agatgctgcc tatatcctgc
     9661 tctcaggtta tcaggagttt gattatgtaa aaagagcaat gaaccttagt gtggtggact
     9721 atttggtcaa gcctgttgat aaggtagagc tgggaaatct gctggagaag attgcaggtc
     9781 agctcggcga gagagggaag aaaagtcaga ctcttagtca agaattagac gaggctggat
     9841 ttgttagtta tttaggggat aaggagaatt ggtggatagg tctatccaag gaaaaacaag
     9901 gttccttcac cattccctac tatgtcttgg gccaagactg gcagattttc atttctggcc
     9961 aacctctaga tggtttagtc gttacacctt ttgaagctcc ttatcaagaa cactttgaac
    10021 gctggaagct gaatgctgag aaaaccctct tttacggttc tgtaaatttg cagcagtctg
    10081 agagtctctt tgcctattac gaaccgattt atagggttat cattcaggga aatctcaatc
    10141 aaatcgtaga agagttaaat ctcttggaga aggtagttct tgaaaatacg ccgcgtgttc
    10201 cgattactaa acagcttttt attcagtttg tcatggatgt tttccattta tttgaacatc
    10261 tcaaagctga tgacctgaca gacatcgtca aaaccattca tgctattcaa tccttcgatg
    10321 aattggtttc ttatatcaag gaaactctga tcagcttttt cggtcaatac cgtatgaatg
    10381 aaaatgtggt cagtgtgctg gaagtcattg gtcgtgatta ccaaaaagag ctttccctca
    10441 aggatatcag taaggctctc tttatcaatc ctgtctatct agggcagttg attaagcgtg
    10501 aaaccgattc gacctttgca gagttactaa acaaacaacg tattaaggct gcccaacaac
    10561 ttttgctttc aactagtgac agcatcgaag atatttgtta tgctgttggt tacagtaacc
    10621 ttggatattt ctataaagtt ttccgaaaat tgtgcggaaa atcgccaaaa gcctaccgaa
    10681 aacaggtaga aactatacta taaaatttgt attcctttac aaaaggtgct ataatattat
    10741 caggaggttc tatcatgaaa aagaaaccaa tttatctatg ggtcttgcta atcttgtctg
    10801 cccttatttc agttccgtct ctgtttggaa ttgtgagtcc cttgcctagt aaggaagccc
    10861 ttcgtgctgc tcagaaacaa gttgcagggg tcaatgctca gcaattagaa gaccagctta
    10921 attataccta tagagtagca gaagcatctc attctatttt taatgttgct ttgattgtgc
    10981 tatctactat tttagtggtc gtagcgattg tcttccttgt tcgtaaaaat ttgcaatatg
    11041 caaactatac ttacgttggc tatgttttgt tagctattat tggttcgatt tatggctatg
    11101 ttggtttaca agacgctgtg cagttggttc aagatgagag catgcgtttg acagtgagta
    11161 ttggttcaaa agctgttagc attttctata tcgtcatcaa tgttctcttc ctagcccttg
    11221 tcttctataa gatgtggcga caacagaaag ccttggcaga agaagaggaa acagaagagc
    11281 ttgcctaagt attgacaaaa aagaactatc aagatacaat cttggtagtt gttttttgat
    11341 tatagataaa atcatggagg tacatatgaa gacaatttct ttagtttata ttagtttgag
    11401 tggcaacact gaaagttttg tgacgcgctt gaaagactat ctcttgtccc agtacaaagg
    11461 gattgaggtt caaaagattc atatcaagga tttagtcaag gaaggcaaaa atttctatga
    11521 aatggaccat ccctatgtcg cttttttgcc gacctatctc gaaggtggga atggcgtgga
    11581 taacggagat gttgagattt tgacgacacc ggtgggagat tttattgcct atggtaacaa
    11641 tgctagtaag tgttttggtg tggttgggtc aggaaatcgt aactttaata accaatactg
    11701 cctaacagcc aagcaataca gtcaacgctt tggctttcct gtattggctg actttgaaat
    11761 gcgaggcatg ctggaagata tcaaacatgt cgcagctatt atcgcagatt tgtatgagtt
    11821 ggaaaaggag aattaatact caatgaaaat caaagagcaa actaggaagc tagtcgcagg
    11881 ttgctcaaag cacagctttg aggttgcaga tagagctgac gtggtttgaa gagattctcg
    11941 aatagtataa agttcttata agaggtggtt gaagttgttc aactgttttt tgagtataaa
    12001 cagtctttaa gaacgtaaaa aagcataagt tcaggtcttc aaaaccttgt tcttatgctt
    12061 tttatcatag aaatatttgc tgaattttct cttgaaatga aaccttatct tcatctcgcg
    12121 cttgtccctt accctgcttt tccgattgcg agtgcgtaga taaagaagat ggcgaagcca
    12181 aagaggaaaa tcaatcccgc aatggcaagg tgtttgagcc aagaaggaag atttttgttt
    12241 tcacgcgtta ccaaggcgta attcaaaaga gcaaagaaag gtgttgtcag gaaagagcca
    12301 atcatggcaa agcggagcat ggttgaaacc tgaccagcga agaacttgat aatgacgata
    12361 ccgatgatag cagtgatggt catccagatg ttcaaagatt tacgattgtc ctctttttga
    12421 ctgattagca gtcggagaga ttcctgatta acgcgagaat agccatcgat aacagttata
    12481 actgttccaa agatacagag gaaggcaata aaggtaatca agtaacggga ccattcgcca
    12541 agaacagagg catacatgcc cacgaattga gagatgtatt tggctgaagc agcttcaacc
    12601 gcctgccctg taggatactg aatcagtgct cccagtgcca caaagaagac ggctaggata
    12661 gctgttccaa tataaccagt gttaaagtca aacacagcgt cttctgtgtt aaagttgacg
    12721 gtctttctct tttcagctga ccaaagtgaa ttgatggctg aaatttcaat aggagccggc
    12781 atccatccta ggagggagac gatgaagggc agagctgcca tttgccaagg tgtcttctcg
    12841 acaaaatcag aactgtattc tggatgcttg accgccgcaa tgataactgc aagaacagtc
    12901 gcaatggtta aggcagacat aatccatttg accatgccgt ctaaaagttt gtagcctcca
    12961 aagagtagca tagcccaaat gattgcaacg agaatgaggg accactgagt aatgctaagt
    13021 ccaatcattg ggaaggcact ggcgatgata gctgagcaca gaatggcaac accagccgtg
    13081 ttgaccatag ccgaaaagac attgaggata aagaaaatcc agagatagag ttttcctttt
    13141 tcggcataac cttcaaccaa agtctttcca gtatcagctg tgtattcagc accaaaacgg
    13201 aaaaatggat atttaaagac attggctaag atgaccaaga gaagtagaga ccaaccgtaa
    13261 gaaccgccag cttgagttga ggatacaatg tgggaacctc caacagcggc agttgccatt
    13321 aggattccag gtcccattgc ttttagcttg cttgcccagg ttgattgatt taaggaaata
    13381 gcttgcgaca tgataaatac tcctttttga attttcagaa taatctgtat atgtaatcta
    13441 tattctacaa aaaattttgg aaaaatgcaa gagtattttg aaaaaagata gaaaatttac
    13501 aaagaaaatc tgaaataact gttatgatat agcagattga aactagaata gtacactttt
    13561 gcttctaaaa cattgttaga aatcgatttg actgtcctga ttgatttacc ctgttcttat
    13621 ttcatttcac tatagtaagg tgcagcagga taaagcaaaa ccgagaagtt tctttctcgg
    13681 ttttgcttat tatgaggttc ctattttcta tgctccaaga gttgattgat gtgatctact
    13741 tttttagcct ctcttttata gagaatagcc cagatgatga gatagacaat cgcaaactcg
    13801 ataatgagct ggaggtagaa aatccagtgg aaggggaacc aaccagcaag agttgctagt
    13861 gggacaaagc cagccagcat aaggaagaaa tgagtcagag tggcacgaag catgctccag
    13921 tcacggctga ataagcggtt gccaaagttg aagagcatac cgatggctgc ccagataagt
    13981 gtgcagtaga gcaagaccag ggcaccgtga acctgatgct gatccatcac ttggccgatg
    14041 agagagtagg gatttagtgg tgcgtaggta tttggtgcat aaatgagtga aaagaggatg
    14101 gagaggatga ggccgataag aacaccggca gctgcatcgt gaaatacttg ttttttcata
    14161 gttctaattt ctccttgatg gtttttagat aacggcgtga agagtaggtg aagctttcgt
    14221 ttttcaagaa aatttctacc agaccgtttg gcgtgagctt gaggtgagag atggaatcga
    14281 tattgatgat ttctgattgg gaaatttgga taaaattggt tggcaagagt ttaagaacct
    14341 gatagagtcg caaatcaatg ctgtaggtct gactcgcggt ttctgctaga accttccgat
    14401 tctcgatata gaagcgctga atcttgccaa tctcaactag atagacctga tcatcgattt
    14461 ttcctttgat tttttctctt tggtccagat tttctgcgaa ctcgatgact ttctggactt
    14521 tttcggtttc ttgaggtgct tggacaatca gcttttcctc ctcgtaagtc tcactaatct
    14581 gtagttctac tttcataaat ttctctcctt gtttttcata caaaattaat ctcacttctt
    14641 gtacaccttt attaatactc ttcaaaaatc tcttcaaacc acgtcagcgt cgtcttgccg
    14701 taggatagtt gttgactttg tcagttttat ctacaacctc aaaacagtgt tttgagctgt
    14761 ctgcgtctag ctttctagtt tgctctttga tttttattga gtataccact attttactcc
    14821 ctctggcaag ggactttgtc tatgtggagg gattgggctc ctatgtggtg gagtttttct
    14881 gttctttctg aaatatggta taatagcact aattaatttc taggaaaata gatacagaaa
    14941 ggggctgaaa gatgtctcat attattgaat tgccagagat gctggcaaac caaatcgcag
    15001 ctggggaggt cattgaacgt cctgccagtg tggttaaaga gttggtagaa aatgccattg
    15061 acgcgggctc tagtcagatt atcattgaga ttgaggaagc tggtctcaag aaggttcaaa
    15121 tcacggataa cggtcatgga attgcccacg atgaggtgga gttggccctg cgtcgccatg
    15181 cgaccagtaa gataaaaaat caagcagatc tctttcggat tcggacgctt ggttttcgtg
    15241 gtgaagcctt gccttctatt gcgtctgtta gtgtcttgac tctgttaacg gcggtggatg
    15301 gtgctagtca tggaaccaag ttagtcgcgc gtgggggtga agttgaggaa gtcatcccag
    15361 cgactagtcc tgtgggaacc aaggtttgtg tggaggatct ctttttcaac acgcctgccc
    15421 gtctcaagta tatgaagagc cagcaagcgg agttgtctca tatcattgat attgtcaacc
    15481 gtctgggctt ggcccatcct gagatttctt ttagcttgat tagtgatggc aaggaaatga
    15541 cgcggacagc agggactggt caattgcgcc aagcaatcgc agggatttac ggtttggtca
    15601 gtgccaagaa gatgattgaa attgagaact ctgacctaga tttcgaaatt tcaggttttg
    15661 tgtctttacc tgagttgact cgggctaacc gcaattatat cagcctcttc atcaatggcc
    15721 gttatatcaa gaacttcctg ctcaatcgtg ctattttgga tggtttcgga agcaagctta
    15781 tggttggacg ttttccactg gctgtcattc acatccatat cgacccttat ctagcggatg
    15841 tcaatgtgca tccaactaag caagaggtgc ggatttccaa ggaaaaagaa ctgatgaccc
    15901 tggtttcaga agctattgca aatagtctca aggaacaaac cttgattcca gatgccttgg
    15961 aaaatcttgc caaatcgacc gtgcgcaatc gtgagaaggt ggagcaaact attctcccac
    16021 tcaaagaaaa tacgctctac tatgagaaaa ctgagccgtc aagacctagt caaactgaag
    16081 tagctgatta tcaggtagaa ttgactgatg aagggcagga tttgaccctg tttgccaagg
    16141 aaaccttgga ccgattgacc aagccagcaa aactgcattt tgcagagaga aagcctgcta
    16201 actacgacca gctagaccat ccagagttag atcttgctag catcgataag gcttatgaca
    16261 aactggagcg agaagaagca tccagcttcc cagagttgga gtttttcgga caaatgcacg
    16321 ggacttatct ctttgcccaa gggcgagatg gactttacat catagatcag cacgctgctc
    16381 aggaacgggt caagtacgag gagtaccgtg aaagcattgg caatgttgac cagagccagc
    16441 agcaactcct agtgccctat atctttgaat ttcctgcgga tgatgccctg cgtctcaagg
    16501 aaagaatgcc tctcttagag gaagtgggcg tctttctagc agagtacgga gaaaatcaat
    16561 ttattctacg tgaacatcct atttggatgg cagaagaaga gattgaatca ggcatctatg
    16621 agatgtgcga catgctcctt ttgaccaagg aagtttctat caagaaatac cgagcagagc
    16681 tggctatcat gatgtcttgc aagcgatcta tcaaggccaa tcatcgtatt gatgatcatt
    16741 cagctagaca actcctctat cagctttctc aatgtgacaa tccctataac tgtcctcacg
    16801 gacgtcctgt tttggtgcat tttaccaagt cggatatgga aaagatgttc cgacgtattc
    16861 aggaaaatca caccagtctc cgtgagttgg ggaaatatta aaagtataaa aaagtctggg
    16921 aaaaattttc aaaatcagaa aaacgcataa aatcaggtgt tcaaaaacct tgattttatg
    16981 cgttttatca tagaaatatt tacttcatgt tttcctaatt cttttcgaaa ctctttttaa
    17041 accacgtcag ttttatcagt aatctcaaaa cagtgttttg agctaatttt gccagttttg
    17101 tctgtaacat cgaagttgtg tttgaccact ctgcgactgg tttcctagtt tgctctatga
    17161 ttttcacaga gtattaaatt gcgattttgc caagtttctt tattcgtcta aaagtagagt
    17221 ctgttctatg cgtctaatgt acgaattagg ttgaccattt caatagctcc ttgtgcacac
    17281 tcagaaccct tatttcctgc tttagtgcca gctcgttcta tggcttgttc aattgtatct
    17341 gtcgttagca caccaaacat aacaggaatt tcgctattta aactgatttg ggcgattccc
    17401 ttagatacct cgctacatac ataatcataa tgacttgtat tccctctaat gacagctccc
    17461 aagcagataa ttgcatcata ttttttactt tttgccattt ttgatgcaat cagtggtatt
    17521 tcaaaagctc ctggaaccca ggctacctct atatctttct cgtttacatt ctctcttttg
    17581 agattatcta gtgctccaga taataatttt gaagttataa attcattaaa tctcgctaca
    17641 acaataccta ttttaatatt gtttgctact aaattacctt cataagtgtt catttatttt
    17701 tcctccatat ttaaaatgtg acccattcga tttttctttg tttctaaata aaaactatcg
    17761 taaggattgg cttctatttc gattgatatt ctactggaaa tggtaattcc atatttttct
    17821 aactgttcaa ccttgtcagg attatttgtc agtaaatgaa gtgactgaag tcccagatct
    17881 ttaagcattt gtgctccaat atgatattct cttaaatcac cttcaaagcc taatgcaaga
    17941 ttggcatcaa gcgtatccat gccttgatct tgtaaatgat aggcttttaa tttattgata
    18001 agtcccattc ctcgtccctc ctgtcgcaag taaagtaaga cacccgaacc attctcaaca
    18061 atcattttca tagctttatc gaattgctgt ccacaatcgc aacgtaagga gcctaaaaca
    18121 tcccctgtta aacattcgga gtggacccga cataatacat tggcttcatc ctctatgttt
    18181 cccataataa gagcaagatg atgttcccca tttagtttat ctatatagct aattgctttg
    18241 aaattaccgt atctagtagg catattgaca gttgaaactc gttctaccag ctgatcatat
    18301 acttttctat attcttgtaa ttctttgatg gtaattagtg gaatgttgtg tttcttcgag
    18361 aactgaatta aatcatctgt tctcatcatt ttgccatcat gattcattat ttcacaacat
    18421 aggccacact cttttagtcc agctaatttt aataaatcaa cagttgcttc tgtgtgtcca
    18481 cttctttcta gaacaccacc tttttttgca attaaaggaa acatgtgtcc tggcctgcga
    18541 aaatcagagg gtgttatatc ttcagctaca cacatacgtg cggtcagtcc tctttcctcg
    18601 gcagaaatac ctgtggtcgt ttctttataa tcaattgaaa ctgtaaaagc agtcttatga
    18661 ttatctgtat tgttttcaac cataggtgaa agcattaatt gattagctaa actttcgctc
    18721 ataggcatac aaattaatcc tttggcataa gtagccataa aattaacatt ttctgttgta
    18781 gctgcttgtg cagaacaaat taagtctcct tcattttctc tatccttgtc gtctataaca
    18841 agaacaagtc gtcccttctg caatgcttct aatgcttctt gtatttttcg atattccatt
    18901 gactgattat cctttctgct aaaatccatt ttgatataat agttccttag atatttctga
    18961 ttttggagag ttatccatca gtttttgcac atatttacct aagatatcat tttcaagatt
    19021 tactgtactc ccgacttgtt tactcttaag aatggtttgt tccaaggtat gagggataac
    19081 agatactgaa aagtttactt tggagacttt agcgacagtc agactaatgc cgtcaattgt
    19141 aatagatcct ttttcaacta ttaaatctaa aatttctttt tgtgtgttga tttgatacca
    19201 tacagcatta tcatcttttt ttattgacga gatttttcct gtaccatcaa tgtgtcctgt
    19261 aacgacgtga cccccaagtc gaccgttgac agataaggct ctttctagat tcacctcact
    19321 tccatgtttt aatagagtaa gagctgttcg actccatgtt tcattcatta catcaactgt
    19381 aaaggattga tgattgaaat gagtaactgt aagacagata ccatttactg ctatactatc
    19441 gcctaaatgg atatccgtta atatttttga ggctttaatt gatagtttac aattacgaga
    19501 gtctttctgt attctttcaa cttttccgat ttcttcaatt attcctgtga acatggataa
    19561 atcacttcac tttctatgag atagtcattt cctatttgag aaaatgcata aggtttcaat
    19621 ctaatagcgt catttggcaa agaaatacct tcacctccga caggaaactt ggcactacct
    19681 ccaaaaattt ttggtgcaat atatattttc agctcatcaa caatttgttg ttccaaagca
    19741 ctccaattca ttagactgcc cccttctaga actaggctat caatctgcat gtttcctaga
    19801 tgttgcatta aactcgataa gtctatatga ttgccttttt tctttatgga aagtatttca
    19861 cagccatgat tttgatatag cttcatttta tttttgtctt cagaggaagt ggcaatgtaa
    19921 gttttaatat catttgctgt ttttacgatt ttagaggtaa gaggagttcg taaatgtgta
    19981 tcgcatatga tacggatagg atttttccct tcctccaatc tacatgtcag caaaggatcg
    20041 tcttgaataa cagtattgac tcccaccata attgcactaa catggtgtcg taactgctgc
    20101 acatgctttc ttgcttcttc ttcagtaatc catttggatt gatttgtttt agtggctatt
    20161 tttccatcca ttgacattgc atatttcata aaaacatagg gtacatgctg ggtaatatac
    20221 tttctaaaac tttttattaa gttaagacac tcattttcta aaattccaac agtaacttga
    20281 agattatttt cctcaagtat ctttactcct tttccagata caataggatt acagtctagg
    20341 cttccaatga ctactcttgt aataccacta tcgattatag catctataca gggaggtgtt
    20401 ttcccgaagt gacaacaggg ttcaagtgtt acataaagcg tcgctccgac aggggattct
    20461 ctacagtttt taagagcatt tctctcagca tgtgggccac caaaaaactc atgataacct
    20521 tgtccgataa tgtgattatc ttttacaata actgcgccga ccataggatt gggattgacg
    20581 taaccagccc ctttttgtgc cagttttatt gctaatttca tatattttga atcgctcatc
    20641 tcactacctc caaaaaaata tgccttgaat aggggactac tcaaggcata caaaagaaaa
    20701 cttatgcgat taacaaaaat gctctgaaat gacaagtaat catttcagag cacgcaaaaa
    20761 gcacaaatat acttttatct tctttcatcc agactatact gtcggctttg gaatttcacc
    20821 aaatcatgcc tttcggctcg tgggctatac caccggtagg gaattgcacc ctgccctgaa
    20881 gatagttatt caattacaga tgattatagt acttaatttt gaatatgtca acagataaat
    20941 accgattgtt tttgatatac tgtatttgtg ataatcgatt ctcgctcctc ggataaagaa
    21001 aatatgatat actagataaa cgaaataaga gagaaggaat actatgtacg catatttaaa
    21061 aggaatcatt accaaaatta ctgccaaata cattgttctt gaaaccaatg gtattggtta
    21121 tatcctgcat gtggccaatc cttatgccta ttcaggtcag gttaatcagg aggctcagat
    21181 ttatgtgcat caggttgtgc gtgaggacgc ccatttgctt tatggatttc gctcagagga
    21241 tgagaaaaag ctctttctta gtctgatttc ggtctctggg attggtcctg tatcagctct
    21301 tgctattatc gctgctgatg acaatgctgg cttggttcaa gccattgaaa ccaagaacat
    21361 cacctacttg accaagttcc ctaaaattgg caagaaaaca gcccagcaga tggtgctgga
    21421 cttggaaggc aaggtagtag ttgcaggaga tgaccttcct gccaaggtcg cagtgcaagc
    21481 aagtgctgaa aaccaagaat tggaagaagc tatggaagcc atgttggctc tgggctacaa
    21541 ggcaacagag ctcaagaaaa tcaagaaatt ctttgaagga acgacagata cagctgagaa
    21601 ctatatcaag tcggccctta aaatgttggt caaataggag cagagaatga caaaacgttg
    21661 ttcgtgggtc aagatgacca acccgctcta catcgcctat catgatgagg agtggggcca
    21721 gcccctccat gatgaccaag tattgtttga gttgttgtgt atggaaacct atcaggcagg
    21781 cctgtcttgg gaaacggtac tcaacaaacg ccaagctttc cgagaagtct ttcatagcta
    21841 tcaaattcac tcagtcgcag agatgactga cactgaattg gaagccatgc tggagaatcc
    21901 agctatcatt cgaaatagag ccaagctttt tgctacacgc gctaacgccc aagtctttct
    21961 acagttacag gcagagtacg gctcttttga tgcctatctt tggtcttttg ttgaggggaa
    22021 aactgtcgtt aacgatgttc ctgattatcg ccaagcgcca gctaaaacac ccttatctga
    22081 gaaattagcc aaagatctca aaaaacgagg cttcaagttc acaggcccag tcgccgtatt
    22141 gtcttttcta caggctgcag ggctagttga tgaccacgag aatgattgtg agtggaaagg
    22201 tcttaaatga tgtctaacaa aaataaggga attctgattt ttgcgattct ctatacagtc
    22261 ctctttgtgt ttgatggcgt taaattgctg gcttctttaa tgccatctgt cattgcaaat
    22321 tatcttgttt atgtagtttt agctttatat ggctccttct tgttcaagga tagattgatc
    22381 caacaatgga aggagattag aaagactaaa agaaaattct tctttggcgt cttaacagga
    22441 tggctctttc tcattctgat gactgttgtc tttgaatttg tatcagagat gttgaagcag
    22501 tttgtgagac tagatggaca aggtctaaat cagtctaata ttcaaagtac ctttcaagaa
    22561 caaccactac tgatagctgt ttttgcttgt gtcattggac ctctggtaga agaattattt
    22621 ttccgtcagg tcttattgca ttacttgcag gaacggttgc caggtttact aagcattatt
    22681 ctggtaggac ttgtttttgc tttgactcat atgcacagtt tggctctatc agagtggatt
    22741 ggtgcagttg gttacttagg tggaggcctt gccttttcta ttatttatgt gaaagaaaaa
    22801 gagaatatct actatcccct acttgttcac atgttaagca acagcctctc cttaatcatt
    22861 ttagctatca gtatagtaaa atgaaataag aacaggacaa atcaatcagg acagtcaaat
    22921 cgatttctaa caatgtttta gaagtagagg tgtactattc tagtttcaat acactgtaac
    22981 atgtgatgaa aatgccagta atgataccga gaaaaaagct gagaaacttt tcccagcttt
    23041 atttgttata gtcaaagcga atgacttgtt cctgtgcatc tacatgagca tggaccccaa
    23101 agggtacaat tgctcttgga gttgcgtggc cgacattcag attatagaca atcgggatat
    23161 tgctgtcaat gatatctaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag
    23221 gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca
    23281 acatcttttt gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt
    23341 tcccttccca gtctgacaag tcagggaaaa gtttgtattt tgggcagagt tccgtgctat
    23401 ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt
    23461 tcccctcgaa ctgagcactt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac
    23521 gaggtgttcc cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag
    23581 ggcggatttc tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg
    23641 ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct
    23701 tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa
    23761 ttttttgctt gataaccttt tggagttggt cattttcaaa aagataaggt agcaagcgat
    23821 aggtatcgtc tccaccgatg gcacatagga tcatgtcgat gctatcatca gaaaaggcat
    23881 gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat ccttttaacg
    23941 aatggggcaa aaagatggga ttgagtccca gatccttgag acgttggata cccaagtcca
    24001 cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca ataccaatag
    24061 tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac aaaatataag
    24121 agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat ctcttcaaac
    24181 cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag caacctgcag ctagcttcct
    24241 agtttgctct ttgattttca ttgaatataa ctcaaaaaag taagtgaaaa agcaaccgca
    24301 cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg cacttgcact
    24361 acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg ctccaataat
    24421 agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa
    24481 gaagacaagc aaccaaagga acatagaagc taggataact agtacagatt tccagaaagg
    24541 tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt agtacatcaa
    24601 gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc catagccgaa
    24661 agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga ggctagtgat
    24721 gaaaagagct gagtccataa tcatcagttt tggatcatca ttttcttttg gatgctcttt
    24781 ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc cgtataggga
    24841 acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt cctcaaaaat
    24901 agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag caatgtggac
    24961 aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag gaactcctct
    25021 tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc aaaggcgata
    25081 aagacgatta accagaaggc atttggctct ccgtttaggg ggatttcatt atccttaaag
    25141 ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt cacaagggcc
    25201 aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt ctctgtcata
    25261 gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt ttcaatcagg
    25321 gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt tgaactggtc
    25381 aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac gatagttttt
    25441 tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag ttgactttcg
    25501 atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc tgcattgcga
    25561 taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg caatcgacgg
    25621 ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat ggtttcctca
    25681 gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct ttcctccgtg
    25741 accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg agacatttct
    25801 tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg
    25861 agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc aagcgtatcg
    25921 atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct tatcctttct
    25981 catttttcag attttttcac actgtactat tatactacaa aatcggcctt ttgggtaata
    26041 gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa caaagatgca
    26101 agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg atgtggagat
    26161 tccgcgagac aagctggttg tcgtgacagg tttgtcaggt tcagggaaat ccagtctggc
    26221 ctttgatacc ctctatgcgg agggacaacg tcgctatgta gagagtttgt cagcctatgc
    26281 tcgtcaattc ttaggaaata tggagaaggc ggatgtggat gccattgatg gtctcagtcc
    26341 agctatttct atcgaccaga aaacgactag caaaaaccct cgctcgacgg tgggaacaac
    26401 gactgaaatc aatgactatc tgcgtctcct ctacgcacgt gtggggacgc cttactgtat
    26461 caacggacat ggagctatca atgcttcttc tgtggagcaa atcgttgata aggttttgga
    26521 gttacctgaa cgccagcgct tgcagatctt ggcccctgtc atccgcaaga aaaaaggcca
    26581 acataagagt gttatcgaga aggttcagaa agacgggtat gttcgtgtcc gtgtggatgg
    26641 ggaagtctat gatgtgaccg aagtgccaga gttgtctaag agcaagcaac acaatatcga
    26701 tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct ttgattccat
    26761 tgaggctgcc cttcgtattg cagaaggtta tgtcattatc gacaccatgg acgactctga
    26821 gttgttgttc tctgagcatt atgcctgtcc agtttgtggt tttactgtcc cagagttaga
    26881 gcctcgtctc ttctctttca atgctccttt tggctcttgt agtgagtgtg acggcttggg
    26941 catcaagctg gaggtggata ctgatttggt agtgccagat gccagcaaaa ccttacgtga
    27001 gggagcgtta gcaccttgga atcctatctc atccaactac tatccaaaca tgttagagca
    27061 ggccatgaaa gtctttggag tggctatgga taagcctttt gaggacctgt cagaagaaga
    27121 taagaacttg attctctatg ggtcagatgg taaggaattc catttccact atgagaatga
    27181 atttggtggc gtgcgcgata tcgacattcc gtttgaggga gttatcaata atatcaaacg
    27241 tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgtctct acatgaatga
    27301 gctgacctgc ggaacctgtc aaggctatcg tctcaatgac caggccttgt ctgtccgtgt
    27361 gggcggccag caagggccac atattggaga aatctcagac ctgtctatcg ctgaccactt
    27421 ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc gtcccattct
    27481 caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact atctaaccct
    27541 gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca
    27601 gattggttcc aacctatcag gcgtcctcta tatcctagac gagccgtcaa tcggtcttca
    27661 ccagagagac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact tgggcaatac
    27721 tcttatcgtg gtggaacacg acgaagatac catgcgtgaa gctgattatc tgattgacgt
    27781 tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac ctaagcaagt
    27841 ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt
    27901 accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag cgcgtgagaa
    27961 caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt
    28021 gtcgggttca gggaaatcga ctctaatcaa cagcattctt aaaaaagcca ttgcccagaa
    28081 gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga ttgagcatgt
    28141 cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt ctaacccagc
    28201 tacctataca ggagtttttg acgatatacg tgaccttttt gctcagacaa atgaagccaa
    28261 gattcgaggc tacaagaagg ggcgcttcag tttcaacgtc aagggaggtc gctgtgaagc
    28321 ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg tttatgtggc
    28381 ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc actacaagga
    28441 aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat ttttccaaca
    28501 cattccgaaa attcaacgca aactccagac catcaaggat gtagggctag gctatgtgac
    28561 cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga agttagctag
    28621 cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgagc cgacgacagg
    28681 gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg tagacgatgg
    28741 caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag accatatcat
    28801 tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag gaactccaga
    28861 agaagtagct gccaatgaag ccagctatac aggacactat ttgaaaggaa agttacatca
    28921 tgaataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta gatggtatca
    28981 tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca aacggaacag
    29041 tctttatcag ccgtgaccgt caggtcttag tgacagactc tcgctatatc atcgcagcta
    29101 agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct gtcattgcag
    29161 gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt tcagtatctt
    29221 attaccaccg tatgcaggca gcttttgcag gtttggactt gcttccacaa actcaatttg
    29281 tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc aaggcttgtt
    29341 ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga aaaactgaaa
    29401 ttgaaattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct agcttatctt
    29461 ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca
    29521 aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat gaccactatg
    29581 tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag gcagagattt
    29641 acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca ggcttaggtt
    29701 tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat ggcgactact
    29761 ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc tactttagcc
    29821 agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca ggtatctata
    29881 tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag acaggttgtg
    29941 aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc aagaaaaaag
    30001 tacgaaaatg acgaaaaaag tcaaaaaaaa ttaaaaatag gtcgcaagtc ggatgttttt
    30061 tatggtataa tagactaaac tgatagtaac atgtagcgaa aggggtaggt acatgattaa
    30121 aatttataca gtctcaagtt gtactagctg taaaaaagca aaaacctggc tcaatgccca
    30181 ccagttaagt tataaagaac aaaaccttgg taaagaagga attacgagag aagaattact
    30241 ggatattcta accaaaacag ataacggaat agccagcatc gtttcgtcta aaaatcgcta
    30301 tgccaaagcc cttggagtgg atattgaaga tttgagtgtc aatgaagttc tcaatctgat
    30361 tatggaaaca ccgagaattt taaagagccc aatccttgta gatgaaaaac gcctgcaagt
    30421 tggctacaag gaagacgata ttcgtgcctt cctaccacgc tctgtccgta atgtagaaaa
    30481 tgcagaagca cgtttacgtg cagctctata aacatcaagg ctgggagcac ttcccagtct
    30541 tattctattt taatttcaaa aagaaagaag agagaaatga aaaaaatagt tcttgttagt
    30601 ctagctttcc tttttgtcct ggttggttgc ggacagaaaa aagaaactgg aacagctaca
    30661 aaaacagaaa aggatacgct tcagtcggca ttgccagtta ttgaaaatgc cgagaagaat
    30721 acagttgtaa ccaagacttt ggtcttgccc aagtcagatg atggtagcca gcaaactcaa
    30781 accattacat acaaggacaa gacttttttg agcttaacga ttcaacaaaa acgtccagtt
    30841 tctgatgagt tgaagattta tatcgaccaa catggagtgg aagaaactca aaaagctctt
    30901 cttgaagcgg aggagaagga taagtctatc attgaagctc gtaaattggc aggtttcaaa
    30961 cttgaaacaa aactattgag cgcaacggaa cttcaaacaa cgactagttt tgattttcaa
    31021 gttctggatg tcaagaaggc ttcccagttg gaacatctga agaatattgg tttggaaaat
    31081 cttttgaaaa atgaaccaag caaatatatt tcagatagat tggcaaatgg cgcgacagaa
    31141 caatagaaaa tccaaataaa tagactgcct gaattgtaga aggtaaggaa ttatgctata
    31201 atggtactat tctaaggaaa gagggtgtta gaatgggatt tactgaagaa acagtacgtt
    31261 ttaaattgga cgattccaat aaaaaagaaa ttagcgaaac tttgacagat gtttatgctt
    31321 cgttgaacga taagggttac aacccaatta accaaatcgt aggttacgta ttgagtggag
    31381 accctgccta cgttcctcgt tataataatg cacgaaatca aatccgtaag tatgagcgtg
    31441 atgaaatcgt tgaggaattg gttcgctact acctaaaagg acaaggagtc gatctataac
    31501 ctatgagaat tatgggattg gacgtcggtt caaaaacggt aggggtggcg attagcgatc
    31561 cgcttggttt tacagctcaa gggcttgaaa tcatccagat aaatgaagaa caaggccaat
    31621 ttggttttga ccgcgttaag gaattggttg atacttacaa ggtggaacga tttgtagtgg
    31681 gcttgcctaa aaacatgaac aatacaagtg gaccgcgcgt agaagctagt caagcctacg
    31741 gagcaaagct agaagagttt tttggtttac cagtagacta tcaggatgaa cgcttgacaa
    31801 cagtggctgc tgagcgcatg ttgattgaac aagcagatat cagtcgcaat aagcgcaaga
    31861 aagtcattga taagttagca gctcagctga ttttacaaaa ttatttagat agaaaatttt
    31921 aatataaagg agaggctatg tcacacgatc ataaccacga ccacgaagaa cgtgaactaa
    31981 tcacactagt agatgagcaa ggaaatgaaa ccttgtttga aatccttttg acaattgatg
    32041 gaaaagaaga atttggtaaa aactatgttc ttctagtacc agttaacgca gaagaagacg
    32101 aagacggaca agttgaaatc caagcttact cattcattga aaatgaagat ggaacagaag
    32161 gcgaattgca accaatccca gaagactcag aagacgaatg gaacatgatt gaagaagtct
    32221 tcaacagctt tatggaggag taaaaacgtc cgggggacgt ttttagccct gcgctagaaa
    32281 ttagaaacgc aggtagtctg ggagactgta tcagcccaac tccagaaatg gggaagagtt
    32341 ggaacgtcca gtgaacattt ttaccccata ttcacattca tagtagctag ttattagcta
    32401 accaggtaag aggtcgggac gaaaatcctg gccttgtttt tattagtaac catactttaa
    32461 tgcgataatt gattggactt ttgtcaagga gatgtgtatg tttgaagtag aagaatggct
    32521 ccatagtcgg attggtttga attttcgatc aggtttgggc cgaatgcagc aagcggtgga
    32581 tttgttagga aatcctgagc agtcttaccc tattatccac gtaacaggga ctaatgggaa
    32641 aggatctacc attgctttta tgagggaatt atttatgggg catggcaaaa aagttgcgac
    32701 ctttacctcc cctcatatcg tctctatcaa tgaccgaatc tgcattaatg ggcaacctat
    32761 agcagacgca gactttatcc gtttgactga tcaggtcaag gagatggaga aaacgcttct
    32821 gcaaactcct gcccagttgt ccttttttga attgctgacc ttagttgctt ttctttattt
    32881 tagggagcaa gaggtggatt tggttttatt agaagtggga attggtggct tacttgacac
    32941 gaccaatgtg gtaactggag agcttgctgt catcacctcc attgggcttg accatcaaga
    33001 aaccttgggt gatagtctag aagcaattgc agagcagaaa gctggtattt tcaaggctgg
    33061 taagaaggca gtgattgcga aattgcctcc agaagctagg cttgtctgtc agaaaaaagc
    33121 cgaatcttta gctgttaacc tttatcaggc aggtcaagat tttttaatgc tgaatggtga
    33181 tttttcaagc tctttactaa atctttcaca gctgaacata ggcttagaag gagtctatca
    33241 gcaggagaat gcagccttgg cgttgcaaac ttttcttctt tttatgggag aaggaaagga
    33301 agctgttgat gaacaggctg taagaaaggc cttggaacag acccattggg ctggtcgctt
    33361 ggagcgtatt cgcccacaga tttacttgga tggtgctcat aacctccctg ccttgactcg
    33421 cttggttgag tttatcaaag aaaaagagca ggaaggctat cgacctcaaa tcctttttgg
    33481 agccttgaaa cggaaggatt atcaagggat gttaggttac ctgactgaaa aattgcctca
    33541 ggtggaactc aaggtgaccg gctttgacta tcagggggct ttggacgaaa gggatgtgac
    33601 aggttacgat atagtttctt ctcaccgaga atttatcagc gattttgaag aaagagcaga
    33661 tgctcaggat ttgctgttcg ttacagggtc tctctatttt atctcagaag tacggggcta
    33721 cctgctggac cgtgagcaga taaattgacc cccttgtttg aacttgttat actaggggaa
    33781 ttgctggtta gagaaaattt ctctaaattg gtagcagaaa ggaaattcat catgaaatta
    33841 aaaagattca cactttctct tgcttctcta gcaagtttta gtctcttagt agcttgttca
    33901 caaagagctc aacaggttca acagcctgtt gctcagcagc aggtccaaca gcctgctcaa
    33961 cagaatacca atactgcaaa tgcaggaggt aaccaaaatc aagcggctcc agtacaaaac
    34021 caacctgttg ctcaaccgac cgatattgat gggacttata ctggtcagga tgacggagac
    34081 cgtatcactt tagtggtaac tggaacgact ggtacatgga ctgagctcga atctgacggg
    34141 gatcagaaag tcaaacaggt tacatttgat tcagcaaatc aacgcatgat tattggcgat
    34201 gatgtcaaaa tttacactgt aaacggtaat caaatcgtcg tagatgatat ggatagagac
    34261 ccatcggacc aaatcgtttt aactaaataa gactatgcaa gtagaaaggg ctggattttt
    34321 cagccttttt acttttacct agaaaataat cataaatact tgccttctac cgaatacctg
    34381 cgttatacta gtatcaatta cttgttttta gcattcaaac tatcaaggag gggatatgaa
    34441 atataggaaa tttcaattat tgatgtccaa gtatggcttt agtctttcga ttatgctact
    34501 tgaactttgt cttgtttttg gtctctttct ttatttagga cgcatggctc ccattttatg
    34561 gattactgtc ctcattctac tgagtatcat cacaatcatt tcgatagtca accgtaatac
    34621 gactcctgag aataaggtaa cctggttgtt agtagccttt gtgccagtat ttggtccctt
    34681 gctctatctg atgtttggtg aaaggcgatt gtccaaaaaa gaaatcaaac aactgaagaa
    34741 gctaggctct atgcatttcc aagaagcaaa tagccagcta ctaaaagaga aattaaaaga
    34801 aagtgacaag gcagcttatg gagtcatcaa gtccttattg agtatggata ccaatgctga
    34861 catctatgat caaactgcct ctacattttt tcctaacgga gaagctatgt ggaaaaagat
    34921 ggtagaagat cttaaaaagg ctgagaaatt tattttcttg gaatattaca ttatagaaga
    34981 aggtttgatg tggaatcgca tactagatat actagagcaa aaggtagctc agggtgtaga
    35041 ggttaagatg ctctatgatg atatcggctg tatggctact ttaacaggag attatgcaca
    35101 tcgacttcgt cagctgggca tcgaggccca taaattcaat aaagttattc ctcgtttgac
    35161 agtggcttat aataacagag atcatagaaa aatattgatt gttgatggtc agatagccta
    35221 tactggtggg gtcaatctgg cagatgagta cattaaccac gtcgagagat ttggttattg
    35281 gaaggatagt ggaattcgct tagacggact agcagtaaaa gctctgacac gcttattttt
    35341 gaccacttgg tacattaatc gaggagaaat tagtgatttt gatcaatatc atttagaaaa
    35401 tcattctatc ccgagtgacg gtttaaccat tccatacgga agtggaccca agccaatttt
    35461 tcgagcgcag gtagggaaaa aagtttatca gagtttaatc aatcaagcaa cagaatcggt
    35521 ctatattacg acaccttatt tgattataga ttatgattta acagagacaa tcaaaaatgc
    35581 agctatgaga ggggtcgatg ttcgaattat caccccttac ataccagata agaagttcat
    35641 tcagttagtc acgagaggag cttatcccga ccttctttct gctggtgttc ggatttatga
    35701 gtatagtcca ggttttattc atagtaagca gatgttggta gacgaagatt ttgcggtggt
    35761 ggggacaatc aatctcgact accggagctt ggtacaccat tatgaaaatg cagtcttact
    35821 ctataaaact ccttctataa gggaaatcgc ccgagatttt cgaaatatat ttgcagattc
    35881 tcaggaagtc tatcctcatt ctatcaaaac gagctggtat caaaagcttg taaaagaaat
    35941 cgcccagcta ttcgccccta tcttataaga aatctagaac ttaggataca aaccagacct
    36001 atttttcttg tcttttacga atagaaagaa agaggagggg aattcatgct aactaaggaa
    36061 gaagtgaatg atatgattga gttcaaacgg acacatttac accgctttcg ggaaattgaa
    36121 acctttgtga aactatgcaa aaaatcactc aaacagccat cgcaagctga caatcctagg
    36181 actttttgat atactaagac agataaattg aacaggagaa acgatatgag tgtgtatggt
    36241 agagtagaag aagttcataa ggagaatcgt gaacctctag aataccaaat cgaacaagaa
    36301 tcgcatcatc gtgaatcaag tcgtcttcct ttggtgaaaa ttttactatg gagtacgctt
    36361 gtaacgggga taactctagg agtaccgcta ttactcgact taatgagtgc acaagaagtg
    36421 caggattttt atgcaggttg ggcgcttcat cagacaggga agatttacag cgactattat
    36481 ggaagtcaag gtttgcttta ttatttgctg acttacgtga gtcagggcgg atttttcttt
    36541 gccatctttg agtggttagc cttggtagca ggaggatttt tcctttttag atcagcggac
    36601 accttgacag agcaaggaga ccaagctgga catctggtga ctatttttta catgctagtt
    36661 acaggtcttg cttttggtgg aggctatgcg actcttttag cgcttccttt cttattcgca
    36721 gcctttagtt tagttgcggc ttacctaagc aatccaagcc atgataaggg atttgtacgg
    36781 attgggctag ctttggcagg cggatttttc tttgctccct tatcatcgct cctgtttatt
    36841 gctgtagtga gtttaggctt gttggtcttt aaccttgggc atagacgttt tgtgcatggg
    36901 ttttatcagt ttcttgcagt ggctttaggt ttttcacttg tcttttatcc aactgcctac
    36961 tatagtgctg caacaggaag ttttggggat gcgattagtg gtattcgtta tcctattgac
    37021 agtattcgct ttgattttac ttctaaaatt ttagagaata tgttttttta tggcttgttg
    37081 tcccttggtt tgggatttgt ggtttgtatc tttttaggtc tctttcaatc caaacccttt
    37141 aaactatacg tcatttcggt tcctgcaagt cttgtggtaa ttttaggttt gattttactt
    37201 ttcttttcac aagagcctct gcacgcttct tatttgatgg tcgtcttccc tgttttccta
    37261 cttttattgg taaccaatat taagagtcaa cagagggggc gtagtgctag aagaagccga
    37321 agagaaacgc cagttagcct atggagtcgt ttcttcaaag gaaatctata tctgctagtt
    37381 tttgggtttg tctatctttt gtctgttcct tttttgatga agtttgtcct ttatccagta
    37441 ccttatcaag aacgtaatcg tcttgctgat ttggtaaaag aggagacaaa tacggaagat
    37501 gctatctatg catgggatga tactgcgact ctttatcgta agagtgagcg cttgtcgcca
    37561 tcggcgattt tgtccccgtt gcactataca gcaactgaag aaaatcgtaa taagttactt
    37621 aatgacttga aagaaaaaca acctaaggtg attgtggtaa atgacaaggt ggtagtctgg
    37681 tctgaagtgg aaacactctt aaaagaaaat taccaacaag taaagactga ttactcagag
    37741 tttaaagtct ataaaattaa ataaccaaat caatatcttg tgtattttta aaaattttag
    37801 gatttttaac acaagatatt gatttttctt tttagagtgg tataatactt tttagaaaga
    37861 acattttaga aaagagcatg catatgattg cactagaaga aaaaattaca attttgccaa
    37921 ctctcttcgt cgagaaacga gatgggagac gtgttgtatt tgatgtggac aagattgaca
    37981 aggctctcca caaggcggct gacaaggtta tggatgtgac acccttggtt gaaaaacgcc
    38041 tcaatgatct gactgagcga attattacag aaattcatag tcgctttcca cagggaatta
    38101 agatttacga aattcaaaat atcgtagaac atgaactcct tgaagccaaa gaatatgcgc
    38161 tggctgagga gtatattact tatcggacac agagggattt tgagcgctca aaagcgacgg
    38221 atatcaactt tagtattcat aaacttctca acaaagacca gacagttgtc aatgaaaatg
    38281 ctaataaaga cagtgatgtc tttaacactc agcgtgattt gacagcaggg attgttggga
    38341 aatcaatcgg actgcaaatg cttcctaagc acgtagccaa tgcccaccaa aagggggata
    38401 tccactatca cgatttggac tacagtccct atacccctat gaccaactgc tgtttgattg
    38461 attttaaggg tatgttggaa aatggtttta agattggaaa tgcagaggta gagagtccca
    38521 agtctatcca gactgcgaca gcacagattt ctcaaatcat tgccaacgtt gcttctagcc
    38581 agtacggtgg ctgttcagct gaccgtatcg atgaaatttt ggcgccttat gcagagaaga
    38641 actatcaaaa acatctcaaa gatgcagaag agtgggtatt gcctgaaaaa cgggaagatt
    38701 acgcttggaa gaaaacgcaa aaggacatct acgatgccat gcaatctctt gagtatgaaa
    38761 tcaatactct cttcacttca aatggacaaa caccttttac ttcgttaggt tttggtctgg
    38821 gaaccagtcg ttttgaacga gaaattcaaa aagctatttt aaacattcgc atcaagggtc
    38881 ttggttcaga acaccgtacg gctatctttc ctaaacttat tttcactctg aaaagaggcc
    38941 ttaatttaga ggaaggaact cccaactacg acatcaagca gttggctctt gagtgtgcaa
    39001 ccaaacggat gtatccagat gttttatctt acgataagat tgttgacttg acaggatcct
    39061 tcaaggtgcc tatgggttgc cgttctttcc tccaaggatg gaaggatgaa aatggtgtag
    39121 aagtcaattc aggtcgcatg aatctgggtg ttgtgacggt taatctgcct cgtattgctc
    39181 ttgagtctga aggtgatatg aataagttct gggaaatctt caacgagcga atgaatatcg
    39241 cagaagatgc tcttgtttac cgtgtcgaac gcactaaaga ggcgacacca gcgaatgctc
    39301 ctattcttta tcagtacggt gcttttggcc atcgtctagg taaagaagaa agtgttgacc
    39361 agctctttaa gaatcgtcgt gcgaccgttt cgctgggcta tatcggcttg tatgaagtag
    39421 cgacagtttt ctttggtaac agctgggaaa gtaatccaga tgctaaggaa ttcacgctag
    39481 acatcattca cgatatgaaa cgccgtgtag aagagtggtc agaccaatat ggctaccatt
    39541 tctctatcta ctcaacacca tccgaaagtc tgacagaccg tttctgccga ctagatatag
    39601 acaagtttgg ctctattcct gatatcacag acaaggaata ctacaccaac tctttccact
    39661 acgatgttcg taaaaatcca acaccgtttg aaaaattgga ctttgagaaa gtctatccag
    39721 aagcaggtgc gtcaggtggt ttcatccatt attgtgagta tccagtcctt cagcaaaatc
    39781 caaaggcctt ggaagctgtc tgggattatg cttatgaccg tgtaggctat ctaggcacca
    39841 atactccgat tgaccgttgc tacaagtgtg actttgaagg ggattttgaa ccaactgaga
    39901 gagggtttgc ttgtccaaac tgtggcaata gcgatcctaa aacagtagac gttgttaaac
    39961 ggacttgtgg ctatcttggc aatcctcaag cgagaccgat ggttaacggg cgtcacaagg
    40021 aaatcgctgc gcgtgtcaaa catatgaatg gttcaacgat taaaatagct gggcatcaag
    40081 taacaaatta gaaagaaatg aaatgggaaa atatcaacta gacgataagg ggcgcgcaca
    40141 agtgacccgt tatcacgaga aatactctaa aggtggagct ggtaagaaag aacgcttgct
    40201 tagcttcaga gaacaatttt taaacaagaa caagaaaaaa taaaagtgag agccagctct
    40261 cgcttttctc atagtgggag gtagggatgg aattacgcag accaagatta gcggataaga
    40321 aagctgtttt agatatgatg acagagtttg aaaagagcca atcagcccat gatggaggat
    40381 tttgggatac agagaacttt gtgtatgaag agtggttgga aagcaatcag gaacaggaaa
    40441 tggggattaa tctgcctgaa ggatgggttc ctgcaattca gttagtggct ttttctgaga
    40501 aaggtcaagc agttggattt cttaatctcc ggttgcgcct cagtaacttt ctactagaag
    40561 aaggtgggca cattggctac tccatccgtc catctgaaag aggcaagggt tatgcaaaag
    40621 agactctccg tcagggcttg caagttgcta aggaaaagaa catcaagaaa gctctggtga
    40681 cctgtagcgt gaataatcct gctagcagag cagtcattct agcaaatggt ggaatatttg
    40741 aggatgctcg caatggagtc gagcgttatt ggatagaggt agcgaatgaa taatccaaaa
    40801 ccacaagaat ggaaaagcga ggaacttagt caaggtcgta tcattgacta caaggccttt
    40861 aactttgttg atggcgaagg cgtgcgtaac tctctctatg tagcaggctg tatgtttcac
    40921 tgcgagggat gttataatgt tgcgacttgg tcttttaatg ctggcattcc ctatacagca
    40981 gaattagaag agcagatcat ggcagatctt gctcagccct atgttcaagg tttgactttg
    41041 ttgggagggg agccttttct caatactggc attctcttgc cacttgttaa gcggattcgg
    41101 aaagaattgt cagacaagga catctggtcc tggaccggct acacttggga agaaatgatg
    41161 ttggaaactc cagataaact ggaactcttg tcactgattg atattcttgt cgatggaaga
    41221 tatgatcgaa ctaagagaaa tcttatgctc cagtttcgag gttcgtctaa ccaacgaatt
    41281 atcgatgtgc aaaaatcgct caaaagtggg caagtagtga tttgggacaa gctcaatgac
    41341 ggaaaagaaa gctatgaaca ggtgaagaga gaatgaagaa aaaagactta gtagaccaac
    41401 tagtctcaga gatcgagacg gggaaagtca ggacactggg aatatacggt catggagctt
    41461 caggtaaatc aacccttgca caggaattgt cccaagcttt agattctact acagtaaatt
    41521 tgctagaaac agatccctat atcacctccg gacgctattt ggtagtaccc aaggacgcgc
    41581 cgaatcaaaa ggtgacagcc agtctgccag tggcgtatga actggagagt ttgcagagag
    41641 atatccttgc cttgcaggcg ggtatggatg tcttgacaat tgaagaacct tggaaggcta
    41701 gtgaagtctt gtctggagcc aaaccaattt tgattgtcga agggatgtct gttggttttc
    41761 tacccaagga actctttgaa aaaaccatct gtttctacac ggatgaggag accgaattaa
    41821 agcgacgctt tgctagagat acgactgtga gaaatcgcga tgcatccttt atattggcta
    41881 gccatcagat gagacgggag cagtatctgc gatactataa agaaactgag tctaaggcgg
    41941 atatcttagt ggaccaatca gaagataaat ttgatgtcaa gaggacttaa cttatgtata
    42001 gaagaaaatc cctaatttta gaaagaaaaa gtaggaaaac agtttcatcc caaaaaaacg
    42061 aaaaaaccta acaaatccct tgcaatcgca ggggatttgt gttattctat tatggtgctg
    42121 taaattacag ccttagtttt gatgcaagag gttgcgacac gctcggttgc attgccacgc
    42181 aacaccgcgt cggttttctt gtggagctag cctattatct taaatagacg aaaaggagaa
    42241 aaagatggca aacaaaaaaa tccgtatccg tttgaaagct tacgaacacc gtacgcttga
    42301 cacagcggct gcaaaaatcg tagaatcagc tactcgtaca ggtgcacaag ttgcgggtcc
    42361 aatcccactt ccaactgaac gtagcctcta cacaatcatt cgtgcgactc acaaatacaa
    42421 agactctcgc gaacaatttg aaatgcgtac acacaaacgt ttgatcgata tcgttaaccc
    42481 aactcaaaaa acagttgatg ccttgatgaa attggatctt ccaagtggtg taaacgtaga
    42541 aatcaaactt taatctaaaa tataaaagag cagaggctgg tgtttcaatc taattgaaca
    42601 cgggctaaac tcggtgtgaa aaagataaac ttcctagtgt ctgctagaca ctgcgtcagt
    42661 ttcctatttt cacgttgagt ttgacgccct ttgtatctta gacttgagca taaaaaacgc
    42721 tcgttaaaaa ctttttgaat aaaaatatag aaaaggaact attttctcat gacaaaagga
    42781 atcttaggga aaaaagtggg aatgactcaa atcttcactg aagctggcga attgatccct
    42841 gtaacagtta ttgaagcaac tccaaacgtt gttcttcaag ttaaaactgt tgaaacagac
    42901 ggatacaacg ctatccaagt tggtttcgat gacaaacgcg aagtattgag caacaaacct
    42961 gctaaaggac atgtagcgaa agctaacacg gctcctaagc gcttcattcg tgaattcaaa
    43021 aacgttgaag gcttggaagt tggtgctgaa attacagttg aaacattcgc agctggagac
    43081 gttgttgacg taactggtac ttctaaaggt aaaggtttcc aaggtgttat caaacgccac
    43141 ggacaatcac gtggaccaat ggctcacggt tctcgttacc accgtcgtcc aggttctatg
    43201 ggacctgttg cacctaaccg cgtattcaaa ggtaaaaacc ttgcaggacg tatgggtggt
    43261 gaccgcgtaa caattcaaaa tcttgaagtt gtacaagttg ttccagaaaa gaacgttatc
    43321 cttatcaaag gtaacgtacc aggtgctaag aaatctctta tcactatcaa atcagcagtt
    43381 aaagctggta aataataaag aaaggggaaa tcagtcacaa tggcaaacgt aacattattt
    43441 gaccaaactg gtaaagaagc tggccaagtt gttcttagcg atgcagtatt tggtatcgaa
    43501 ccaaatgaat cagttgtgtt tgatgtaatc atcagccaac gcgcaagcct tcgtcaagga
    43561 acacacgctg ttaaaaaccg ctctgcagta tcaggtggtg gacgcaaacc atggcgtcaa
    43621 aaaggaactg gacgtgctcg tcaaggttct atccgctcac cacaatggcg tggtggtggt
    43681 gttgtcttcg gaccaactcc acgttcatac ggctacaaac ttccacaaaa agttcgtcgc
    43741 ctagctctta aatcagttta ctctgaaaaa gttgctgaaa acaaattcgt agctgtagac
    43801 gctctttcat ttacagctcc aaaaactgct gaatttgcaa aagttcttgc agcattgagc
    43861 atcgattcta aagttcttgt tatccttgaa gaaggaaatg aattcgcagc tctttcagct
    43921 cgtaaccttc caaacgtgaa agttgcaact gctacaactg caagtgttct tgacatcgca
    43981 aatagcgaca aacttcttgt cacacaagca gctatctcta aaatcgagga ggttcttgca
    44041 taatgaattt gtatgatgtt atcaaaaaac ctgtcatcac tgaaagctca atggctcaac
    44101 ttgaagcagg aaaatatgta tttgaagttg acactcgtgc acacaaactt ttgatcaagc
    44161 aagctgttga agctgctttc gaaggtgtta aagttgccaa tgttaacaca atcaacgtaa
    44221 aaccaaaagc taaacgtgtt ggacgttaca ctggttttac taacaaaact aaaaaagcta
    44281 tcatcacact tacagctgat tctaaagcaa tcgagttgtt tgctgctgaa gctgaataat
    44341 ctaaggagga aatatcgtgg gaattcgtgt ttataaacca acaacaaacg gtcgccgtaa
    44401 tatgacttct ttggatttcg ctgaaatcac aacaagcact cctgaaaaat cattgcttgt
    44461 tgcattgaag agcaaggctg gtcgtaacaa caacggtcgt atcacagttc gtcaccaagg
    44521 tggtggacac aaacgtttct accgtttggt tgacttcaaa cgtaataaag acaacgttga
    44581 agcagttgtt aaaacaatcg agtacgatcc aaaccgttct gcaaacatcg ctcttgtaca
    44641 ctacactgac ggtgtgaaag catacatcat cgctccaaaa ggtcttgaag taggtcaacg
    44701 tatcgtttca ggtccagaag cagatatcaa agtcggaaac gctcttccac ttgctaacat
    44761 cccagttggt actttgattc acaacatcga gttgaaacca ggtcgtggtg gtgaattggt
    44821 acgtgctgct ggtgcatctg ctcaagtatt gggttctgaa ggtaaatacg ttcttgttcg
    44881 tcttcaatca ggtgaagttc gtatgattct tggaacttgc cgtgctacag ttggtgctgt
    44941 cggaaacgaa caacatggac ttgtaaacct tggtaaagca ggacgtagcc gttggaaagg
    45001 tatccgccca acagttcgtg gttctgtaat gaaccctaac gatcacccac acggtggtgg
    45061 tgaaggtaaa gcaccagttg gtcgtaaagc accatctact ccatggggca aacctgctct
    45121 tggtcttaaa actcgtaaca agaaagcgaa atctgacaaa cttatcgttc gtcgtcgcaa
    45181 cgagaaataa tattaaacta gtcgcttaag caactagtaa atccgccagc tcggtagcgc
    45241 tccataggag tgcaagccgc tgtggtacaa catttaaagg agaaaatata aaaatgggac
    45301 gcagtcttaa aaaaggacct ttcgtcgatg agcatttgat gaaaaaagtt gaagctcaag
    45361 ctaacgacga aaagaaaaaa gttattaaaa cttggtcacg tcgttcaacg atcttcccaa
    45421 gtttcattgg ttacactatt gcagtttatg acggacgtaa acacgtacct gtttacatcc
    45481 aagaagacat ggtaggccac aaacttggtg aatttgcacc aactcgtact tacaaaggtc
    45541 acgctgcaga cgacaagaaa acacgtagaa aataaggaga acataaatgg cagaaattac
    45601 ttcagctaaa gcaatggctc gtacagtacg tgtttcacct cgtaaatcac gtcttgttct
    45661 tgataacatc cgtggtaaaa gcgtagccga tgcaatcgca atcttgacat tcactccaaa
    45721 caaagctgct gaaatcatct tgaaagtttt gaactcagct gtagctaacg ctgaaaacaa
    45781 ctttggtttg gataaagcta acttggtagt atctgaagca ttcgcaaacg aaggaccaac
    45841 tatgaaacgt ttccgtccac gtgcgaaagg ttcagcttca ccaatcaaca aacgtacagc
    45901 tcacatcact gtagctgttg cagaaaaata aggaggtaaa atcgtgggtc aaaaagtaca
    45961 tccaattggt atgcgtgtcg gcatcatccg tgattgggat gccaaatggt atgctgaaaa
    46021 agaatacgcg gattaccttc atgaagatct tgcaatccgt aaattcgttc aaaaagaact
    46081 tgctgacgca gcagtttcaa ctattgaaat cgaacgcgca gtaaacaaag ttaacgtttc
    46141 acttcacact gctaaaccag gtatggttat cggtaaaggt ggtgctaacg ttgatgcact
    46201 ccgtgcaaaa cttaacaaat tgactggaaa acaagtacac atcaacatca tcgaaatcaa
    46261 acaacctgat ttggatgctc accttgtagg tgaaggaatt gctcgtcaat tggagcaacg
    46321 tgttgctttc cgtcgtgcac aaaaacaagc aatccaacgt gcaatgcgtg ctggagctaa
    46381 aggaatcaaa actcaagtat caggtcgttt gaacggtgca gatatcgccc gtgctgaagg
    46441 atactctgaa ggaactgttc cgcttcacac acttcgtgca gatatcgatt acgcttggga
    46501 agaagcagat actacatacg gtaaacttgg tgttaaagta tggatctacc gtggtgaagt
    46561 tcttccagct cgtaaaaaca ctaaaggagg taaataacca atgttagtac ctaaacgtgt
    46621 taaacaccgt cgtgaattcc gtggaaaaat gcgcggtgaa gcaaaaggtg gaaaagaagt
    46681 agcattcggt gaatacggtc ttcaagctac aactagccac tggatcacta accgccaaat
    46741 cgaagctgct cgtatcgcca tgactcgtta catgaaacgt ggtggtaaag tttggattaa
    46801 aatcttccca cacaaatcat acactgctaa agctatcggt gtgcgtatgg gatctggtaa
    46861 aggggcacct gaaggttggg tagcaccagt taaacgtggt aaagtgatgt tcgaaatcgc
    46921 tggtgtatct gaagagattg cacgtgaagc gcttcgactt gctagccaca aattgccagt
    46981 taaatgtaaa ttcgtaaaac gtgaagcaga ataaggagaa ggcatgaaac ttaatgaagt
    47041 aaaagaattt gttaaagaac ttcgtggtct ttctcaagaa gaactcgcga agcgcgaaaa
    47101 cgaattgaaa aaagaattgt ttgaacttcg tttccaagct gctactggtc aattggaaca
    47161 aacagctcgc ttgaaagaag ttaaaaaaca aatcgctcgt atcaaaacag ttcaatctga
    47221 agcgaaataa tagactaggg aaggagaaat ttcaatggaa cgcaataatc gtaaagttct
    47281 tgttggacgt gttgtatctg acaaaatgga caagacaatc acagttgtag ttgaaacaaa
    47341 acgtaaccac ccagtctatg gtaaacgtat taactactct aaaaaataca aagctcatga
    47401 tgaaaacaat gttgccaaag aaggtgatat cgtacgtatc atggaaactc gcccgctttc
    47461 agctacaaaa cgtttccgtc ttgtagaagt tgttgaagaa gcggtcatca tctaatcaaa
    47521 cctgaaagga gaaaactgaa atgattcaaa cagaaactcg tttgaaagtc gcagacaaca
    47581 gcggtgctcg cgaaatcttg actatcaaag ttcttggtgg ttcaggacgt aaatttgcaa
    47641 acatcggtga tgttatcgtg gcatctgtaa aacaagctac tcctggtggt gcggttaaaa
    47701 aaggtgacgt tgttaaagca gttatcgttc gtactaaatc aggtgctcgt cgtgctgatg
    47761 gttcatacat caaatttgac gaaaacgcag cagttatcat ccgtgaagac aaaactcctc
    47821 gcggaacacg tatctttggc ccagttgcac gtgaattgcg tgaaggtggt ttcatgaaga
    47881 tcgtgtcact tgctccagaa gtactttaat ttttaggaac aaactagtcc cctagcttca
    47941 agctagggtg cccttatggg cgtaagaaaa atcaaggaga aacctaatgt ttgtaaaaaa
    48001 aggcgacaaa gttcgcgtaa tcgctggtaa agataaggga acagaagctg ttgtccttac
    48061 tgcccttcca aaagtaaaca aagttatcgt tgaaggtgtt aacattgtta agaaacacca
    48121 acgtccaact aacgagcttc ctcaaggtgg tatcatcgag aaagaagcag ctatccacgt
    48181 atcaaatgtt caagttttgg acaaaaatgg tgtagctggt cgtgttggtt acaaatttgt
    48241 agacggtaaa aaagttcgct acaacaaaaa atcaggcgaa gtgcttgatt aatcacgaag
    48301 gaaaggagaa gtataatggc aaatcgttta aaagaaaaat atcttaatga agtagttcct
    48361 gctttgacag aacaattcaa ctactcatca gtgatggctg tgcctaaagt agataagatt
    48421 gttttgaaca tgggtgttgg tgaagctgta tcaaacgcta aaagccttga aaaagctgct
    48481 gaagaattgg cacttatctc aggtcaaaaa ccacttatca ctaaagctaa aaaatcaatc
    48541 gccggcttcc gtcttcgtga aggtgttgcg atcggtgcaa aagttaccct tcgtggtgaa
    48601 cgtatgtacg aattcttgga taaattggta tcagtttcac ttccacgtgt acgtgacttc
    48661 cacggtgtcc caacaaaatc atttgatgga cgcgggaact acacacttgg tgtgaaagaa
    48721 caattaatct tcccagaaat caacttcgat gacgttgaca aaactcgtgg tcttgacatc
    48781 gttatcgtaa caactgctaa cactgacgaa gagtcacgtg cattgcttac aggccttgga
    48841 atgccttttg caaaataata taggaggtaa atctaatggc taaaaaatca atggtagcta
    48901 gagaggctaa acgccaaaaa attgttgacc gttatgctga aaaacgtgct gcattaaagg
    48961 cggcagggga ctacgaaggt ttatctaaat tacctcgcaa cgcctcaccg actcgtttac
    49021 ataatcgttg tagagttacg gggcgcccac attcagttta ccgcaaattt ggtctgagtc
    49081 gtatcgcttt tcgcgaactt gcgcataaag gtcaaattcc tggtgtaaca aaagcatctt
    49141 ggtaatttaa gatatcaagg gtgtcaaaac tccaagtaaa aataggaaac ttgacgaaga
    49201 aactaaagtt tctaggaaag tttatctttt tcacacagag tttagcccgg gttcaattgg
    49261 gcttgccaat ttgaacccga gctacagctt tggcaaaaaa gaccaatttg ctttggagca
    49321 ttgcttctgc attaaattgt ctatttttgc tcgtgctgtt acgctctttg tatcatgtat
    49381 taactagcaa gtgcaacttg caaactacta gtaagaggag aaaaacaaaa tggttatgac
    49441 tgacccaatc gcagacttcc taactcgtat tcgtaatgct aaccaagcta aacacgaagt
    49501 acttgaagta cctgcatcaa acatcaaaaa agggattgct gaaatcctta aacgcgaagg
    49561 ttttgtaaaa aacgttgaaa tcattgaaga tgacaaacaa ggcgtcatcc gtgtatttct
    49621 taaatacgga tcaaatggtg agaaagttat cactaacttg aaacgtgttt ctaaaccagg
    49681 acttcgtgtc tacaaaaaac gtgaagacct tccaaaagtt cttaacggac ttggaattgc
    49741 catcctttca acttctgaag gtttgcttac tgataaagaa gcacgccaaa agaatgttgg
    49801 tggtgaggtt atcgcttacg tttggtaaaa tcaagataca aagctcgtaa agaacaaagc
    49861 aaaattagga agttggagaa gtttgtttac aaacaagcca acttatctat tttgcacagt
    49921 tcttagagcg tgttcagttc agctcttgaa ctaaataagt atctgaaccc cgtgaaaact
    49981 ggccgttctg gcctgacaat ttaacaggag aaaataaaca tgtcacgtat tggtaataaa
    50041 gttatcgtgt tgcctgctgg tgttgaactc gctaacaatg acaacgttgt aactgtaaaa
    50101 ggacctaaag gagaacttac tcgtgagttc tcaaaagata ttgaaatccg tgtggaaggt
    50161 actgaaataa ctcttcaccg tccaaacgat tcaaaagaaa tgaaaactat ccacggaact
    50221 actcgtgccc ttttgaacaa catggttgtt ggtgtatcag aaggattcaa gaaagaactt
    50281 gaaatgcgtg gggttggtta ccgtgcacag cttcaaggat ctaaacttgt tttggctgtt
    50341 ggtaaatctc atccagacga agttgaagct ccagaaggaa ttacttttga acttccaaac
    50401 ccaacaacaa tcgttgttag cggaatttca aaagaagtag ttggtcaaac agctgcttac
    50461 gtacgtagcc ttcgttcacc agaaccatat aaaggtaaag gtatccgtta cgttggtgaa
    50521 ttcgttcgcc gtaaagaagg taaaacaggt aaataatgtt gagtggttga tcatcaacca
    50581 ccaacctatt ttccaacttt gtgcatagca cacgatttaa aactaaagag gtgaaaactg
    50641 tgatttcaaa accagataaa aacaaactcc gccaaaaacg ccaccgtcgc gttcgcggaa
    50701 aactctctgg aactgctgat cgcccacgtt tgaacgtatt ccgttctaat acaggcatct
    50761 acgctcaagt gattgatgac gtagcgggtg taacgctcgc aagtgcttca actcttgata
    50821 aagaagtttc aaaaggaact aaaactgaac aagccgttgc tgtcggtaaa ctcgttgcag
    50881 aacgtgcaaa cgctaaaggt atttcagaag tggtgttcga ccgcggtgga tatctatatc
    50941 acggacgtgt gaaagctttg gctgatgcag ctcgtgaaaa cggattgaaa ttctaatagg
    51001 aggacactag aaaatggcat ttaaagacaa tgcagttgaa ttagaagaac gcgtagttgc
    51061 tgtcaaccgt gttacaaaag ttgttaaagg tggacgtcgt cttcgtttcg cagctcttgt
    51121 tgttgttggt gaccacaatg gtcgcgtagg atttggtact ggtaaagctc aagaagttcc
    51181 agaagcaatc cgtaaagcag tagatgatgc taagaaaaac ttgatcgaag ttcctatggt
    51241 tggaacaaca atcccacacg aagttctttc agaattcggt ggagctaaag tattgttgaa
    51301 acctgctgta gaaggttctg gagttgccgc tggtggtgca gttcgtgccg ttgtggaatt
    51361 ggcaggtgtg gcagatatta catctaaatc acttggttct aacactccaa tcaacattgt
    51421 tcgtgcaact gttgaaggtt tgaaacaatt gaaacgcgct gaagaaattg ctgcccttcg
    51481 tggtatttca gtttctgatt tggcataaga aaggggataa aatggctcaa attaaaatta
    51541 ctttgactaa gtctccaatc ggacgcattc catcacaacg taaaactgtt gtagcacttg
    51601 gacttggcaa attgaacagc tctgttatta aagaagataa cgctgctatc cgtggtatga
    51661 ttacagcagt atctcactta gtaacagttg aagaagtaaa ctaatgaagt tttaggggat
    51721 gtgcactgta ccatccccta aaactagata tagtcatcta tgatgacatc gtataggcga
    51781 gttgatgggg gagacaacct tttctccctt atcggcgcta gcattttaca aaagaggaga
    51841 aaataaaaat gaaacttcat gaattgaaac ctgcagaagg ttctcgtaaa gtacgtaacc
    51901 gcgttggtcg tggtacttca tcaggtaacg gtaaaacatc tggtcgtggt caaaaaggtc
    51961 aaaaagctcg tagcggtggc ggagttcgcc ttggttttga aggtggacaa actccattgt
    52021 tccgtcgtct tccaaaacgt ggattcacta acatcaacgc taaagaatac gcaattgtga
    52081 accttgacca attgaacgtc tttgaagatg gtgctgaagt aactccagtt gttcttatcg
    52141 aagcaggaat tgttaaagct gaaaagtcag gtattaaaat tcttggtaac ggtgagttga
    52201 ctaagaaatt gactgtgaaa gcagctaaat tctctaaatc agctgaagaa gctatcactg
    52261 ctaaaggtgg ttcagtagaa gtcatctaag agaggtgacc tatgtttttt aaattattaa
    52321 gagaagctct taaagtcaag caggttcgat caaaaatttt atttacaatt tttatcgttt
    52381 tggtctttcg tatcggaact agcattacag ttcctggtgt gaatgccaat agcttgaatg
    52441 ctttaagtgg attatccttc ttaaacatgt tgagcttggt gtcggggaat gccctaaaaa
    52501 acttttcgat ttttgcccta ggagttagtc cctatatcac cgcttctatt gttgtccaac
    52561 tcttgcaaat ggatatttta cccaagtttg tagagtgggg taaacaaggg gaagtaggtc
    52621 gaagaaaatt gaatcaagct actcgttata ttgctctagt tctcgctttt gtgcaatcta
    52681 tcgggattac agctggtttt aataccttgg ctggagctca attgattaaa actgctttaa
    52741 ctccacaagt ttttctgacg attggtatca tcttaacagc tggtagtatg attgtcactt
    52801 ggttgggtga gcaaattaca gataagggat acggaaacgg tgtttccatg attatctttg
    52861 ccgggattgt ttcctcaatt ccagagatga ttcagggcat ctatgtggac tactttgtga
    52921 acgtcccaag tagccgtatc acttcatcta tcattttcgt aatcattttg attattactg
    52981 tattgttgat tatttacttt acaacttatg ttcaacaagc agaatacaaa attccaatcc
    53041 aatatactaa ggttgcacaa ggtgctccat ctagctctta ccttccgtta aaggtaaacc
    53101 ctgctggagt tatccctgtt atctttgcca gttcgattac tgcagcgcct gcggctattc
    53161 ttcagttttt gagtgccaca ggtcatgatt gggcttgggt aagggtagca caagagatgt
    53221 tggcaactac ttctccaact ggtattgcca tgtatgcttt gttgattatt ctctttacat
    53281 tcttctatac gtttgtacag attaatcctg aaaaagcagc agagagccta caaaagagtg
    53341 gtgcctatat ccatggagtt cgtcctggta aaggtacaga agaatatatg tctaaacttc
    53401 ttcgtcgtct tgcaactgtt ggttccctct tccttggtgt gatttccatt ttaccgattg
    53461 cagctaaaga tgtatttggt ctttctgatg ttgttgcctt tggtggaaca agtctcttga
    53521 tcattatctc tacaggtatc gaaggaatca agcaattgga aggttaccta ttgaaacgta
    53581 agtatgttgg tttcatggac agaacagaat aaaagtattt actgaatcag taaatactga
    53641 gggagtggag gtttaaactc tgacatttgt aagagttgga tctcccctct tctattttgt
    53701 ttttaaatag gggtgaaaag actttttgct tctatttaaa aataaaataa ggagatcaaa
    53761 tcatgaatct tttgattatg ggcttacctg gtgcaggtaa gggaactcaa gcagcaaaaa
    53821 tcgtagaaca attccatgtt gcacatatct caacaggtga tatgttccgc gctgcaatgg
    53881 caaatcaaac tgaaatgggt gttcttgcta agtcatatat tgacaagggt gaattggttc
    53941 ctgacgaagt tacaaatgga atcgtaaaag aacgcctttc acaagatgat attaaagaaa
    54001 caggattctt attggatggt tacccacgta caattgaaca agctcatgcc ttggacaaaa
    54061 cattggctga acttggcatt gaactagaag gtgttatcaa tattgaagtg aaccctgaca
    54121 gcctcttgga acgtttgagt ggccgtatca tccaccgcgt aactggagaa actttccaca
    54181 aggtctttaa cccaccagtt gactataaag aagaagatta ctaccaacgt gaagatgata
    54241 agcctgagac agtaaaacgt cgtttggatg ttaatattgc tcaaggagaa ccaatcattg
    54301 ctcactaccg tgccaaaggt ttggttcatg acatcgaagg taatcaagat atcaatgatg
    54361 tcttctcaga tattgaaaaa gtattgacaa atttgaaata aagcgttttt cacacttgca
    54421 aaaatccgct acaaatgtta tactgagata gtctgactta taattgttgt ctctgtgtct
    54481 agaggcatcg aatcgaaatt tatggaggtg cttttgcgtg gcaaaagacg atgtgattga
    54541 agttgaaggc aaagtagttg atacaatgcc gaatgcaatg tttacggttg aacttgaaaa
    54601 tggacatcag attttagcaa cagtttctgg taaaattcgt aaaaactata ttcgtatttt
    54661 agcgggagat cgtgttactg tcgaaatgag tccatatgac ttgacacgtg gacgtatcac
    54721 ttaccgcttt aaataatcga aaaacttgga gggataagaa atgaaagtaa gaccatcggt
    54781 caaaccaatt tgcgaatact gtaaagttat tcgtcgtaat ggtcgtgtta tggtaatttg
    54841 cccagcaaat ccaaaacaca aacaacgtca aggataagat agaaaggaga aaacatggct
    54901 cgtattgctg gagttgatat tccaaatgac aaacgcgtag taatctcatt gacttatgtt
    54961 tatggtatcg gacttgcaac atctaagaaa attttggctg ctgctggaat ctcagaagat
    55021 gttcgtgtac gtgatcttac atcagatcaa gaagatgcta tccgtcgtga agtggatgca
    55081 atcaaagttg aaggtgacct tcgtcgtgaa gtaaacttga acatcaaacg tttgatggaa
    55141 atcggttcat accgtggtat ccgtcaccgt cgtggacttc ctgtccgtgg acaaaacact
    55201 aaaaacaacg ctcgcactcg taaaggtaaa gctgttgcga ttgctggtaa gaaaaaataa
    55261 tataggaggt aaaagtcttg gctaaaccaa cacgtaaacg tcgtgtgaaa aagaatatcg
    55321 aatctggtat tgctcatatt cacgctacat ttaataacac tattgttatg attactgatg
    55381 tgcatggtaa tgcaattgct tggtcatcag ctggtgctct tggtttcaaa ggttctcgta
    55441 aatctacacc attcgctgct caaatggctt ctgaagctgc tgctaaatct gcacaagaac
    55501 acggtcttaa atcagttgaa gttactgtaa aaggtccagg ttctggtcgt gagtcagcta
    55561 ttcgtgcgct tgctgccgct ggtcttgaag taacagcaat tcgtgatgtg actccagtgc
    55621 cacacaatgg tgctcgtcct ccaaaacgtc gccgtgtata atcatcgcat tacactgctt
    55681 ttcgtttaag agggagtaac taaatgatcg agtttgaaaa accaaatata acaaaaattg
    55741 atgaaaataa agattatggc aagtttgtaa tcgaaccact tgaacgtggc tacggtacaa
    55801 ctcttggtaa ctctcttcgt cgtgtacttc tagcttctct accaggagca gctgtgacat
    55861 ctatcaacat tgatggtgtg ttacatgagt ttgacacagt tccaggtgtt cgtgaagacg
    55921 tgatgcaaat cattctgaac attaaaggaa ttgcagtgaa atcgtacgtt gaagacgaaa
    55981 aaatcatcga actggatgtt gaaggtcctg ctgaagtaac agctggtgac attttgacag
    56041 atagcgatat tgaaattgta aatccagatc attatctctt tacaatcggt gaaggttctt
    56101 ctctaaaagc gactatgact gttaacagtg gtcgtggata tgtacctgct gatgaaaata
    56161 aaaaggataa tgcaccagtt ggaacacttg ctgtagattc tatttataca ccagttacaa
    56221 aagtcaacta tcaagtggaa cctgctcgtg taggtagcaa tgatggtttc gacaaattaa
    56281 cccttgaaat cttgacaaat ggaacaatta ttccagaaga tgctttaggg ctttcagcac
    56341 gtattttgac agaacatctt gatttgttta caaatcttac tgagattgct aagtcaactg
    56401 aagtgatgaa agaagctgat actgaatctg acgaccgtat tttagatcgt acgattgagg
    56461 aactggactt gtctgtgcgt tcatacaact gtttaaaacg tgccggtatc aatactgtgc
    56521 atgatttgac agaaaaatct gaagcagaga tgatgaaagt acgaaatctt ggacgcaaga
    56581 gtttggaaga agtgaaactc aaactcattg atttgggtct tggattaaaa gataaataaa
    56641 ggaggaatac atggcttacc gtaaactagg acgcactagc tcacaacgta aagcaatgct
    56701 tcgcgatttg acaactgacc ttttgatcaa cgaatcaatc gtgacaactg aagctcgtgc
    56761 taaagaaatc cgtaaaactg ttgaaaaaat gattactcta ggtaaacgtg gtgatttgca
    56821 tgcacgtcgt caagcagctg ctttcgtacg taatgaaatc gcatctgaaa actatgatga
    56881 agcaactgat aagtacactt ctactacagc acttcaaaaa ttgttctcag aaatcgcacc
    56941 tcgttatgct gaacgtaacg gtggatacac tcgtatcctt aaaactgaac cacgtcgtgg
    57001 tgatgcagcg ccaatggcga tcatcgaatt agtataaaat catcaatttt gttgagtgtt
    57061 atgatgatgg agtcttgtgc tcttagtcta gctctggtct accgctagga tttcggtcct
    57121 agcgggaaca ctcatcataa gttgggatag tagacgcttg tttacgaaat tgtttttttc
    57181 ttaagaacaa cttcgtaagc aggcgttttt gagtattttc gttagaatta tgctatacta
    57241 tttgaaaaga atcctgttta atgttaaggt ttcttatttt aagaagaatt ggagtttact
    57301 tatgaaagcg attataactg ttgttggtaa agataaatct ggaattgttg caggtgtttc
    57361 tggtaaaatt gcagaattag gattgaatat tgacgatatc tctcaaactg tattggatga
    57421 atattttacg atgatggctg ttgtatctag tgatgaaaag caagatttta cctatcttcg
    57481 taatgaattt gaagcttttg ggcaaacttt gaatgtaaaa atcaatattc agagtgcagc
    57541 gattttcgaa gctatgtata atatctagga ggtcatcatg gatattagac aagttactga
    57601 aaccatcgcc atgattgagg agcaaaactt cgatattaga accattacca tggggatttc
    57661 tcttttggac tgtatcgatc caaatatcaa tcgtgctgcg gagaaaatct atcaaaaaat
    57721 tacgacaaag gcggctaatt tagtagctgt tggtgatgaa attgcggctg agttgggaat
    57781 tcctatcgtt aataagcgtg tatcggtgac acctatttct ctgattgggg cagcgacaga
    57841 tgcgacggac tacgtggttc tggcaaaagc gcttgataag gctgcgaaag agattggtgt
    57901 ggactttatt ggtggttttt ctgccttagt acaaaaaggt tatcaaaagg gagatgagat
    57961 tctcatcaat tccattcctc gcgctttggc tgagacggat aaggtctgct cgtcagtcaa
    58021 tatcggctca accaagtctg gtattaatat gacggctgtg gcagatatgg gacgaattat
    58081 caaggaaaca gcaaatcttt cagatatggg agtggccaag ttggttgtat tcgctaatgc
    58141 tgttgaggac aatccattta tggcgggtgc ctttcatggt gttggggaag cagatgttat
    58201 catcaatgtc ggagtttctg gtcctggtgt tgtgaaacgt gctttggaaa aagttcgtgg
    58261 acagagcttt gatgtagtag ccgaaacagt taagaaaact gcctttaaaa tcactcgtat
    58321 cggtcaattg gttggtcaaa tggccagtga gagactgggt gtggagtttg gtattgtgga
    58381 cttgagtttg gcaccaaccc ctgcggttgg agactctgtg gcacgtgtcc ttgaggaaat
    58441 ggggctagaa acagttggca cgcatggaac gacggctgcc ttggccctct tgaacgacca
    58501 agttaaaaag ggtggagtga tggcctgcaa ccaagtcggt ggtttatctg gtgcctttat
    58561 ccctgtttct gaggatgaag gaatgattgc tgcagtgcaa aatggctctc ttaatttaga
    58621 aaaactagaa gctatgacgg ctatctgttc tgttggattg gatatgattg ccatcccaga
    58681 agatacgcct gctgaaacca ttgcggctat gattgcggat gaagcagcaa tcggtgttat
    58741 caacatgaaa acaacagctg ttcgtatcat tcccaaagga agagaaggcg atatgattga
    58801 gtttggtggt ctattaggaa ctgcacccgt tatgaaggtt aatggggctt catctgtcga
    58861 cttcatctct cgcggtggac aaatcccagc accaattcat agttttaaaa attaagaaaa
    58921 taggagaaat tttaagttct atttaagatt agatgtgtat actataatca ttaaataaag
    58981 acctcctaat attatttgaa acagataaca ctgaattagt ttgaatttga ttttcatcta
    59041 atatctttat ttaatgaact cctaaacttt ttcataataa tctccttcaa aagtcgcctg
    59101 tatgggtggc ttttatttta tcattcatga tataatagaa gcaaacggag gacggaaaat
    59161 ggtaaaagta cgattgtatt tggcacgtca tggcaagacc atgtttaaca cgattggtcg
    59221 cgcgcaaggt tggagcgata ctcccttaac tgctgaaggt gaacgaggga ttcaagagtt
    59281 aggaattggt ttgcgagaat ctgatctaca gtttgagcgc gcttattcga gtgattctgg
    59341 tcgtaccatt cagaccatgg gaattatcct tgaagagctt ggcttgcagg ggaaaatccc
    59401 ttatcgcatg gacaagcgta tcagagaatg gtgtttcggt agttttgatg gagcctatga
    59461 tggcgatctt ttcatgggca ttattcctcg tatctttaat gtggaccacg ttcaccaatt
    59521 gtcttatgct gaactggctg agggcttggt agaggtcgat acagctggtt gggctgaagg
    59581 ctgggaaaaa ctcagtggcc gaattaagga aggctttgaa atgattgcaa aagaaatgga
    59641 agatcaaggt ggaggtaacg cccttgttgt cagccatgga atgactattg gaaccattgt
    59701 ttatctgatt aatggcatgc atccgcatgg tctagataat ggtagcgtga cgattcttga
    59761 atatgaggac ggtcagttta gggttgaagt tgtcggtgac cgtagttacc gagagctagg
    59821 acgtgagaag atggaagaag gctctattta atcagtctag acttgcttgc catgagctag
    59881 ggatttgata agaatatcaa gataagaaaa aacagccgag ggtactcctt tcggctgttt
    59941 ttgatgtgga aaactaaagt gtaatgctat tgcttttaga gattttcata aacaagagca
    60001 aggaacctac tgttagaaca gtcaggatag ttgacaaggc tgcggctaca ccgtaatttc
    60061 ctctgagaac ctctgtataa atagctacag tcattgttct tgttttgaca ttgtagagga
    60121 ggatagagga tagaagtaga gagttctgaa atcagtgtga cccaagatag gatggctcca
    60181 gaaataatac ccgatagcat cattggagtt gtaatcttag caaaggtatt gagacgacta
    60241 cttcctaagc tttcagcagc ttcttcaata cttggtgcta tttgttgtaa gctagcaaca
    60301 gatgagcgaa tagtataagg taatcttctg acagatagag acataatcaa gatgaaagca
    60361 gtccctgtaa tcataagaaa tccacttcca aatagaccag tattgaagga agaaatgaag
    60421 gcaatcccta gaacggttcc tgatacaata taaggtacca tactgaggct gtcaattaag
    60481 tttgtaaaca aattccgttt tctaacggct aggtaggaga taaatgtcgc aaatagaaca
    60541 actagaacta aggcaatcaa agggatacga atggtattga aaatagcaga tcccatacga
    60601 ttgaaagcta ccttgtaact gtttggagaa taacctttaa caaataccat acctgatgtt
    60661 tttaggaaag aggtataaat taagtagatt tgaggtaaaa cagagataaa gataattccg
    60721 tagactgttg cataaatggc agccattttt ccttttgtag tttttttagg ctcaattgga
    60781 tggagcggat tcatgctgaa actgtagcgg tttgcaatgt gtttttggat aaggaaaatt
    60841 gccaaggcaa tgataatcgc cataattgca aaagcagaat ttcctccaac ctcgctaata
    60901 aattgggtat aaatcaggac agggaaagtc cgatatcctt cgccaatcaa cataggcgtt
    60961 ccaaagtctg agaatgctct cataaataca agcaaggagc tgctagtaag gttggaacta
    61021 gaagaggtaa aacaaccgtt acgataggtt taaatccgaa ggaccccatg ctttcagctg
    61081 cttcaagtag agaattgtca atactgttca ttgttccagc aacatataga aataccagtg
    61141 ggaatagttg cagtgtaaag acaagtacaa ttcctttgaa tccataaata tcgatagctg
    61201 gaagatgaag ggcatttgtc aaaaatttag tgatgccccc atttcgtccc agcaagagaa
    61261 cccaggagta ggctcctacg aaaggagctg acatggaagc aatgataatc aatatttgta
    61321 gaaatttctt ccccttgaag tcatacatag agaagagata agctaatagg gttcctacaa
    61381 ctaaggaagt gacagtagcg gtaatggaaa ccctgaaact gttgactagt gtctcagagt
    61441 agtaggcttt actaaagaaa gtgacaaaat tagatagtga gaattgtcct tcatgtataa
    61501 gtgcttgctt gagcacggta acgataggat aaacgagaaa gacaagatag gtaagaaaga
    61561 tgaagaaaga ggaggctgtc caaatattta gttttttaca ttccatggtt gactcctttt
    61621 atcaggtttt gggaaccatc tacagaaaag atgtttaatt tttgcgtatt gattcgtaga
    61681 cgaatacgat tgcctttttg tagttcttct tcaaaagttg attcttcact aacttaaatt
    61741 tttgaggcaa aacctgtctc aatgaaatac tccgtattta gtccaagata gacgctatcg
    61801 ctaatagttc cttcgatatc tccagattca tctttgataa actcttcggg acgaatgctt
    61861 acatgaatag cttgctcctc aacctgatca agagctggca ttcgaagggc atagccatct
    61921 gaaaagacga tataagcgcc gtcgctccgt ttttcaagat tggcagggat aatatttgtg
    61981 cgtccgataa aggttgccac aaactcatta gctggtttat gatagagtta ttttggtcgg
    62041 ccgatttgtt ggatcacccc atctttcata acagcaattt ggtctgaaat agccatggct
    62101 tcttcttggt cgtgggttac ataaacagtt gtaattccca cttcgtgttg gatttctcgg
    62161 atggcttgac gcatatccaa gcgaagtttg gcctccagat tactaagtgg ctcgttcatg
    62221 aggagaacac ttggattaac cgctaaggcg catgccaagg tgacacgttg ttgttgtcca
    62281 ccactgagtt tatcgggctt tcgatccgca tattgagcaa tttgcatgag ttcaagatac
    62341 ttgttggtct gttgaatcaa ttcttctttt ggaaccttct tttgcataag accaaaagca
    62401 acgttgtctc ggacagtcaa atgtgggaaa atagcgtagt tttggaaaac catcccgata
    62461 ttgcgtttgc tgggttccat attattgatt tttgtatcat cgaagtaaaa ttctccacct
    62521 tcgatactgt tgaaacctgc aatcatacga agaagggtcg ttttcccaca tcctgaaggt
    62581 ccaagaaggg taaagagact tccttttgga attgtaatgt tcaaattctc aataacaggg
    62641 acatcgtggt agattttttt ggcgttaata attttgatct cactcatagt gaacctcttt
    62701 tactgtttag attggatatc tgtaaagact tcgttgtatt tcttaacgat atctgattta
    62761 ttcttgatga cataatcata atcttcagtg agtgttttga ttttgtcaat tggtttcatg
    62821 ttttcgcttg ttttagcatt tttacgaaca ggacggttag tagtggttgt accaagtgta
    62881 tcttgtactt cttgagagat aataaaatcg ataaatttct tggcattttc catattttta
    62941 gattttttaa cgatagcagc actagcaggt aggaagacgg ttccttcttt tggatagact
    63001 accttaatgt tagctccgtc atttaagagt ttaactgctg gatcttcata agagagacca
    63061 acagtcattt ctccatcagc gactgcttta tagacaccag atgaacttaa accgatttta
    63121 tagtatattg aaactagaat agtacacatc tacttctaaa acattgttag aaatcgattt
    63181 gactgtcctg attaatttgt cttgttctta tttcatttta ctataccatc aataagtgtg
    63241 aaaagatctt ttacataaga ccaagcctta tcatctttgt aaccaccttg agcttgtagc
    63301 atatttgtta attgagcaaa ggcgctagaa gagtttgctg ggtcagcagt tgcgattttt
    63361 ccttttagtt caggtttgag aaggtcgcta tatccttcga tgttcatgcc tttagttaaa
    63421 tcagggtgga cgattaaaac actaccatct agtgtataag gagtagagaa gccagttgtg
    63481 ttttgatatt ctttgataac attatcattt tcttttgaaa tatagttttc aaagagttct
    63541 ccgtgggtag catattgtgt ataagaacca ccaaagataa catcagctac aggaacttct
    63601 ttttctgact ctagtttttt gaaaagttct ccagtaccag cttgaatcag ttctattttg
    63661 ataccatatt tttcttcaaa ggcaggaata gttgctccaa ttaagccttc tgagtttggt
    63721 gaataaacga ctagcgaacc accgtctcct ttatcagatg aactgtcatc ggcagattca
    63781 ttagaagaac aagcagcata atacatccat ttctttttca tgatggatac ctccgttgtg
    63841 ttatttaagt ttattttaaa acaatataag cgtttttaaa acctacaatt ctatcctata
    63901 gtgtattgaa tctataacag tacactttga ctgctaaaat atttctataa attaatttga
    63961 ctttcctgat agagatgttc acatcttatt tcaattcact atattagagt aaaattctct
    64021 acaaaaagaa gaatagccta tttgactatt cttccgagtg atttcaattt ctttggggaa
    64081 atatggagat actttttaaa tactttggca aaatatttat agtctgaaaa tccaacttgg
    64141 tcagagatag cgcttaaagg ggagttggga gattcagcca tcttatctat agcttgtttc
    64201 aggcgatatt gtaagatata ttcatttaga gtcatgggga agtcttcttt gataacctta
    64261 tatagatgct tgttatctgc aaatagctag agcatttcaa ggaaatgaac tagaaataac
    64321 aattaatatg gtggttcaga aatacctttt gataatcaat aagatcttca ggatgaagtg
    64381 cgttgactcc atccatttca tatttccgat ttaataaacg atatttgttt tcaccaaatt
    64441 gatgaaaagg gagtagttga acttggtcga tatttaatga gttaaataga gtagcgaatt
    64501 tttctgcatc ctctaaacta ttgttaaaat taggaataac tgggattctt aaaacgatag
    64561 ttttattttg agaaaaagca taatgaatgt ttttaataat catttgatta aaaaccccag
    64621 tcactttttt atgttttata gaattataat gttttaggtc tgtgtagata aaatccacat
    64681 attgaattaa atcaataaat ttttcatgat caacaaaggc agtagtttca atggcagtgt
    64741 gtatgtgatg ttctttagct gattttaaga tggctttagc aaattcaaac tgagcaaata
    64801 tttcacctcc tgataaagtt aaacctccac cggattcttc gtaaaattct ttgtctttta
    64861 atacctctgt aataatttct tctacagtct tttcttcacc gactaaggtg aatttctctc
    64921 gttgagcatc tttcattttt tcaggtttca ttctttgaga ttcaggatta gaacaccatg
    64981 gacagcgcag aggacatcct tttaaaaaaa cagttgtacg aatacccggg ccgtcatgaa
    65041 ttgaaaagtg ttgaatatta aaaataattc ctttagatat ttccataaga gttcctcctc
    65101 ttcataagtc tatcctatca caaaaacgaa agaaaaacaa ttacgaacga aagtttaatt
    65161 tgttgttttt tgctttttat tttggtagaa taaaacggag gtgtaaaatg aaaagattgg
    65221 aacaaattat taaattagta tcagaatatg aaaagatcga cgttaataca ttatcggaaa
    65281 aattaaatgt atcgaaagta acgattagaa aagatttaga taaattagag tcaaaaggtt
    65341 tattacacag agagcatgga tatgctgtat taaatagtgg agatgactta aatgtacgtt
    65401 tgtcaattaa ttatgaaatt aagagaaaaa ttgttcagga agcagtaaaa ttggtgtcag
    65461 ataatgaaac aataatgata gaatctggat cgacctgtgc tttacttgct gaggaaattt
    65521 gcaagcaaaa aagaaatgtt acgattgtaa caaattcatt ttttatagca aattttgtga
    65581 gagcttatga ttcatgtcgt attattgttc ttggtggaga gtttcagaag gattcacagg
    65641 ttactgtggg acctttatta aaagaaatga tacagacttt tcatgtgcgt caagcttttg
    65701 ttgggacaga tggctacgat aaagagatgg gctttacagg aaaagattta atgcgcagtg
    65761 aggtagttca atatatttca gcagcgtcgg ataaagtcat tgtactaact gactcaagta
    65821 aatttgataa aaggggtaca gtaagaagat ttgctttaag tcaagtctat gaagtaataa
    65881 cagacgaaaa actttctaaa caaaatatag ctacattaga aaatgctggg ataatggtta
    65941 aggtagtttc gtaagaggtt aagtgtatga atcaagatag gaataaactg ctttctaaaa
    66001 ttgcttatct gtattatatt gaaaacttaa atcagtcaca aatagcagca aaattaggaa
    66061 tttatagaac ctctattagt agaatgttaa cagaagcaag gaatgcagga attgttaaaa
    66121 ttgaaataga gaattttgat acaaatatgt ttaagttgga aaattatgta aaagaaaaat
    66181 atggtctgga aagtttagaa attattccaa atgaatttga tgataatcca acaattttat
    66241 ctgaaagaat ttctcaagtt gcagcaggtg tccttaggaa tttaattgat gataatatga
    66301 aaattggctt ttcttggggg aaaagtttaa gtaatttagt agatttaatt cacagtaaaa
    66361 gtgtccgaaa tgttcacttc tatcctctag caggtggtcc tagtcacata cacgctaaat
    66421 accatgtgaa tacactgatt tatgaaatgt ctagaaaatt tcatggagag tgtacattta
    66481 tgaatgcaac gattgtgcaa gaaaataaat tgttagcaga tggtattttg caatcaagat
    66541 attttgaaaa tttgaaaaat agttggaaag atttagatat agctgtagtc ggaattggtg
    66601 attttagcaa taaaggaaaa catcaatggt tagacatgct tacagaggat gactttaaag
    66661 aattgaccaa agttaaaact gtaggagaaa tttgttgtcg attttttgat tcaaaaggta
    66721 aagaagtcta tgaaaactta caggaaagaa cgatagcaat ctctttggaa gatttaaaaa
    66781 atattcctca aagtttagct gttgcttacg gtgatacgaa agtatcttcg attctttctg
    66841 tcttgcgtgc taatttagta aatcatttga ttacagacaa aaatacaatt ttaaaagttt
    66901 tggaagaaga tggggatttg acttttagag agattctagg tgagtgaaaa tgatagactg
    66961 atcagtttat cgttttttct ttttagtcga ttgcacattt gtgctcatat aaacaaaaat
    67021 agtttatctg ttgtttttgg attgacaact ttattatgta gttgtattct atagttacaa
    67081 aagaaaattt taaaatttca aatgaaaaaa gctttttaca tagtgaaatg aggaggaatt
    67141 tatggaaatt attgttccag atcaaattat catgggttta attttatatg ctggtgatgc
    67201 gaaacaacat atttataaag cgttagatta cataaaaaat ggtacatgtg aacggtgtga
    67261 agaagaaatc cagttagctg atgccgcctt attagaagcc cataatctac aaacaaaatt
    67321 cttggcacaa gaagcgtctg gtacaaagac agaaattaca gctctctttg ttcattcaca
    67381 agatcatctc atgactagta tgacggagat taatttaatc aaagaaatta ttagtttgag
    67441 aaaagaactt cataaaaaat aatactagag tattatcatt gttattaaca tagaggagga
    67501 aaacataatg gtgaagattg gtttgttttg tgcagcaggt ttttctactg gtatgcttgt
    67561 aaataatatg aaaattgcag cgcaagctag tggagttgag gcagaaatag aggcgttttc
    67621 tcagtctaaa ttagcggatt atgcgccaaa tatagatgtt gcactattgg gtccacaagt
    67681 tgcttataca ttagataaat caaaagaaat ttgtgataag tgtgatgttc cgatagctgt
    67741 tattccgatg atggactatg gtatgttaga tggaaaaaaa gtattagatt tggccctatc
    67801 tttgattagt gggtaagaaa aggagattta ttatggcaaa gatggatgtt cagaaaatca
    67861 ttgcaccgat gatgaagttt gtgaatatgc gtggcattat agctctaaaa gatgggatgt
    67921 tagcaatttt gccattgaca gtagttggta gtttattctt gattatggga caattgccgt
    67981 tcgaaggatt aaataagagc attgctagtg tttttggagc taattggaca gagccgttta
    68041 tgcaagtata ttcaggaact tttgctatta tgggtctaat ttcttgtttt tcaattgcct
    68101 attcttatgc taagaatagc ggagtagagg ctttaccagc tggagttcta tctgtatctg
    68161 cattctttat tttgctaaga tcatcttata tccctaaaca aggtgaggca attggggatg
    68221 ctattagtaa agtttggttt ggaggtcaag gaattatcgg tgctatcatt ataggtttgg
    68281 tagtaggaag tatttatacc ttctttataa agagaaaaat tgttattaag atgccagaac
    68341 aagttccaca agctattgcc aaacagtttg aagcaatgat tccagcattt gtaattttct
    68401 tactttctat gattgtatat attttagcga agtcattgac taatggcgga acattcatag
    68461 aaatgattta ttctgctatt caagttccat tgcaaggttt aactggatct tggtatggtg
    68521 caattggaat tgcattcttt atatcatttt tgtggtggtt tggtgttcat ggacaatcgg
    68581 tagtaaatgg agtagtgaca gctctgcttt tatctaatct tgatgctaat aaagctatgt
    68641 tagcctctgg taatctatca ttagaaaatg gtgcacatat tgttactcaa caatttttag
    68701 attcattttt aattctatca ggttcaggga ttacgtttgg tcttgtagtt gccatgcttt
    68761 ttgcagcaaa atcaaaacaa taccaagcct taggaaaagt tgccgctttt ccagcaatat
    68821 ttaacgtaaa tgagccagtt gtatttggat ttccgattgt catgaatcca gttatgtttg
    68881 tacctttcat tcttgttcct gtacttgcag ctgtgatagt atatggagct attgcaacag
    68941 gtttcatgca gccattctca ggggtaacat tgccttggag tacaccagct attttatcag
    69001 gatttttggt gggtggatgg caaggagtta ttactcagct ggtgatatta gcgatgtcta
    69061 cattggttta ttttccattc tttaaagtac aggatcgttt agcttaccaa aatgaaatca
    69121 aacaatctta gaggtatttg tgtgttactg ttaaactcac acatttgtgc taaaaattag
    69181 agagttaaaa tttttctagt taaaagcttg aaaatttcta taaaaatcgg tattatattt
    69241 tcgaaagaaa taaaaatatt ttcgaaagaa aggtggttac gatggtaaat acagaagtag
    69301 caagaacaac aatcaagaca gaatattttg gcagccttac tgaaaggatg aacaaatatc
    69361 gagaagatgt tttaaataaa aaaccttata ttgatgctga gagagcagtt ctagcaacac
    69421 gcgcctatga acgatacaag gaacaaccta atgtcctaaa acgtgcatat atgctgaaag
    69481 aaattttgga aaatatgact atctatattg aagaagaatc tatgattggg ggaaatcaag
    69541 cttcttccaa taaagatgct cctatttttc cggaatatac gctagaattt gttctcaatg
    69601 agttggatct ttttgaaaag cgtgatggag atgttttcta tattacagaa gaaacaaaag
    69661 aacaacttag aagtattgct ccgttttggg aaaataataa tttacgtgct agagctggtg
    69721 ccttattacc tgaagaagtg tctgtttata tggaaacagg attcttcggt atggaaggta
    69781 agatgaattc tggagatgct cacctagcag ttaactatca gaaacttttg caatttggct
    69841 taagaggttt tgaagagcgg gctcgtaaag caaaagcagc tctagattta acagatccag
    69901 caagtattga taaatatcat ttttacgact ctatatttat cgtaatcgat gctattaaag
    69961 tatatgcaaa gcgctttgtt gctcttgcta aaagtttagc cgaaaatgca aatcctaaac
    70021 gtaagaaaga attacttgag attgcagata tttgctctag agtcccatat gaaccggcaa
    70081 ctacttttgc agaagctatt caatcagttt ggtttattca atgtatttta caaattgaat
    70141 ctaatggcca ctctctttca tatggccgtt ttgatcaata tatgtatcca tatatgaagg
    70201 ctgatttaga aagtggtaaa gaaacagaag atagcattgt tgaacgtctg acaaatcttt
    70261 ggattaagac aattacaatt aataaggttc gcagtcaatc acatacattt tcttcagcag
    70321 gaagtccttt atatcaaaat gttacaattg gtggacagac tcgagataag aaggatgctg
    70381 ttaacccatt atcttatttg gtattaaaat cagttgcaca aacccatcta ccgcaaccta
    70441 atctaactgt acgttaccat gcaggtttag atgctcgttt catgaatgag tgtattgaag
    70501 tgatgaaact tggttttggt atgcctgcat ttaataatga tgagattatt attccttctt
    70561 ttattgcaaa aggagtattg gaagatgatg cttatgatta cagtgccatt ggatgtgttg
    70621 aaacggcagt tccagggaaa tggggctatc gttgcacagg tatgagttat atgaacttcc
    70681 ctaaggttct acttatcacg atgaatgatg gaattgatcc ggcttcgggt aaacggtttg
    70741 caccaagctt tggtcatttt aaggatatga agaacttttc tgaattagaa aatgcttggg
    70801 ataaaacact aagatatttg acacgaatga gtgttattgt tgaaaattct attgatttat
    70861 cattggaacg agaagttcct gatattctat gttcagcatt gactgatgat tgtattggtc
    70921 gtggaaaaca ccttaaagaa ggtggagcag tatatgatta tatatcagga ttgcaagttg
    70981 gaattgcaaa tttgtcggat tcattagctg caattaaaaa attggtgttt gaggaagaac
    71041 gtataagccc aagtcagctt tggcatgcac tggaaacaga ttatgccgga gaagaaggta
    71101 aggtcattca agaaatgttg attcatgatg cacctaagta tggtaatgat gatgattatg
    71161 ctgacaaatt ggttactgct gcttatgaca tttatgttga tgaaattgct aaatatccta
    71221 atacacgtta tggaagaggt ccaattggag gaattcgtta ttcaggaaca tcttctatct
    71281 cagccaacgt agggcaggga cgtggaacat tagcaactcc agatggacgc aacgcgggta
    71341 caccgttagc agagggttgt tcaccatcac ataatatgga tcaacacggc cctacatctg
    71401 ttttaaaatc tgtttcaaaa ttaccaacag atgaaatcgt aggtggggtt ctcttaaatc
    71461 agaaagtaaa tcctcaaacg ttagccaaag aagaagataa attaaaacta attgctttgt
    71521 tacgaacatt ctttaatcgt ttacatgggt accatattca atacaatgtt gtttccagag
    71581 agacgctgat tgacgctcag aaacatcctg aaaaacacag agacttaatt gttcgtgttg
    71641 caggatactc tgcattcttc aatgttcttt ctaaggcaac ccaagatgac attataggac
    71701 gtactgagca tactttgtaa aataaagagg ttctttttat ggaatttatg cttgacacat
    71761 taaatttaga tgagattaaa aagtggtctg aaattttgcc gctagctggg gtaacttcaa
    71821 atcccactat tgcaaaaaga gagggttcta ttaatttttt tgaacgaatc aaagatgtaa
    71881 gagaattgat tggctctaca ccctctattc atgttcaggt gatttctcaa gattttgaag
    71941 gcatcttaaa ggatgctcat aaaattcgaa gacaagcagg agatgatata tttatcaaag
    72001 tacctgttac tccagctgga ttacgtgcaa taaaggcgct aaaaaaagag ggctaccata
    72061 tcactgcaac agctatttat acagttattc agggattatt agctatcgaa gcaggagcgg
    72121 attacctagc tccatattat aatagaatgg aaaatctgaa cattgattca aattctgtca
    72181 ttcgtcaatt agctcttgct attgatagac agaactctcc tagtaagatt ttagctgcat
    72241 cctttaaaaa tgtagcacaa gtaaataatg ctttagctgc aggtgcgcat gctgttacag
    72301 caggagcgga tgtttttgaa tcagctttcg ccatgccatc tatccaaaag gcggttgatg
    72361 atttttctga cgattggttt gttattcaaa atagtcgttc catttagata gagaggaaat
    72421 acatatgaga atttttgcta gtccttctag atatattcag ggggaaaatg ccttgtttga
    72481 aaatgccaaa tcaattttgg atttgggaaa ttaccctatt ctattatgcg atcagttggt
    72541 ttatgatatt gttggaaaac gatttgaaga ttacctacat aggtatggtt tccatattgt
    72601 tctggcgcta tttaatggtg aagcttctga caatgaaatc aatcgagttg ttgccttggc
    72661 tgagaaagaa aattgtgata gtattatcgg tcttggtggg ggaaagacga ttgatagcgc
    72721 aaaagctatt gcagatttga ttgaaaagcc tgttattatt gctccaacaa ttgcatcgac
    72781 cgacgcacct gtatctgctt tatctgttat ttatacagat gaaggtgcat ttgatcatta
    72841 tctattttat tctaaaaatc cagatttagt tttggttgat acaaaagtta tttcacaagc
    72901 ccctaagcgt ttattagcgt ctggtattgc agatggttta gcaacttggg ttgaggcgcg
    72961 tgcggttatg caggcaaatg gaaaaactat gttgggacaa cagcaaacat tggctggagt
    73021 tgcaattgcg aagaaatgtg aagaaacgct gtttgcagat ggtttacagg ctatggcagc
    73081 ttgtgaagct aaagtggtga caccagcatt agaaaatatt gttgaagcta atactttatt
    73141 gagtggtcta ggttttgaaa gtggaggatt agctgcggcg catgcaattc ataatggttt
    73201 tactgcattg acaggtgaca ttcatcattt aacacatggt gaaaaagtag cttatggaac
    73261 tttagtacaa ctattattgg aaaatagacc taaagaagaa cttgataagt atattgagtt
    73321 ttacaaaaaa attggtatgc caacaactct aaaagaaatg catttggatc aagttggata
    73381 tgatgattta ataaaagttg gtaaacaagc aactatggag ggtgagacaa ttcatcagat
    73441 gccgtttaag atttcgcctt cagatgttgc tcaagctatt atcgctgtag atgcctatgt
    73501 aaattcaaaa taaacaataa ggactactgt tttccaaatg gtagtctttt attgatccct
    73561 gtattgaatt ctatagcaga ttgaaatagg atgagaacaa atcgattggg aaagtaaaat
    73621 taatttctat aaatgtttta gcaattgttt cgtactattt cagattcagt ccactatacg
    73681 ttcttcataa atcaaaaagc gacataggtt gtcggctatt tattgtgaat acattaatta
    73741 gcattccagt tttatcttcg gtctaaaata agtattttgt gctatacgag ataagcttct
    73801 tgacttactc cttgatttac tgcataacaa tgggataaaa agtgggagat agagcaattc
    73861 atagtcatca aaattaatga gatacagtat acagtttttt ctttaaacac atttcaaatt
    73921 ccctcaaaaa tggtataata gtaacatcac aaaattggag agagaccatg agtttttaca
    73981 atcataaaga aattgaacct aagtggcagg gctactgggc agaacatcat acatttaaga
    74041 caggaacaga tgcatcaaaa cctaagtttt atgcgcttga tatgttccct tatccgtctg
    74101 gagctggtct gcatgtagga cacccagaag gttatactgc aaccgatatc ctcagtcgtt
    74161 acaaacgtgc gcaaggctac aatgtccttc acccaatggg ttgggatgct tttggtttac
    74221 ctgcagagca atacgctatg gatactggta atgacccagc agaatttaca tcggaaaaca
    74281 ttgccaactt caaacgtcaa atcaatgcgc ttggattttc ttatgactgg gatcgtgaag
    74341 tcaacacaac agatccaaac tactacaagt ggactcaatg gattttcacc aagctttacg
    74401 aaaaaggctt ggcctatgaa gctgaagtgc cagtaaactg ggttgaggaa ttgggaactg
    74461 ccattgccaa tgaagaagtg cttcctgacg gaacttctga acgtggaggc tatccagttg
    74521 tccgcaaacc aatgcgccaa tggatgctca aaatcacggc ttacgcagag cgcttgctca
    74581 atgacttaga tgaactagat tggtcagagt ctatcaagga tatgcaacgc aactggattg
    74641 gtaaatcaac tggtgccaat gtaactttca aagtaaaagg aacagacaag gaatttacag
    74701 tctttactac tcgtccggac acacttttcg gtgcgacttt cactgttttg gctcctgaac
    74761 atgaattagt agatgccatc acaagcacag agcaagcaga agcagtagca gactacaaac
    74821 accaagccag ccttaagtca gacttggctc gtaccgacct tgccaaagaa aaaactggtg
    74881 tatggactgg tgcttatgcc atcaatcctg tcaatggtaa ggaaattcca atctggattg
    74941 cggattacgt tcttgctagc tatggtacag gtgcggtaat ggctgtgcct gcccacgatc
    75001 aacgtgactg ggaatttgcc aaacaatttg accttccaat cgtcgaagta cttgaaggtg
    75061 gaaatgttga agaagctgcc tacacagaag atggccttca cgttaattca gacttcctag
    75121 atggactcaa caaagaagac gctattgcca agattgtggc ttggttggaa gaaaaaggct
    75181 gtggacaaga gaaggtaacc taccgtctcc gcgactggct ctttagccgt caacgttact
    75241 ggggtgagcc aatcccaatc attcattggg aagatggaac ttcaacagct gtccctgaaa
    75301 gtgaattgcc acttgtcttg cctgtaacca aggatatccg tccctcaggt actggtgaaa
    75361 gtccactagc taacttgaca gactggcttg aagtgactcg tgaagatggt gtcaaaggtc
    75421 gtcgtgaaac aaatactatg ccacaatggg caggttcaag ctggtactac ctccgctata
    75481 ttgacccaca caatactgag aaattggctg acgaggatct gctcaaacaa tggttgccag
    75541 tagatatcta cgtgggtggt gcggaacatg ctgtacttca cttgctttac gctcgtttct
    75601 ggcataaatt cctctatgac ctcggtgttg ttccaactaa ggaaccattc caaaaactct
    75661 ttaaccaagg aatgattttg ggaacaagct atcgtgacca ccgtggggct cttgtggcga
    75721 ctgacaaggt tgaaaaacgt gatggttctt tcttccatgt ggaaacaggg gaagagttgg
    75781 agcaagcgcc agccaagatg tctaaatcgc tcaagaacgt tgttaaccca gacgatgtgg
    75841 tggaacaata cggtgccgac actcttcgtg tttatgaaat gtttatggga ccacttgatg
    75901 cttcgattgc ttggtcagaa gaaggtctag aaggaagccg taaattcctt gaccgtgttt
    75961 accgtttgat tacaagcaag gaaattgttg cggaaaacaa tggcgctctc gacaaagttt
    76021 acaacgaaac cgttaaagct gtcacagaac aaattgagtc cctcaaattc aacacagcca
    76081 ttgctcaact tatggtcttt gtcaacgctg ccaacaagga agacaaactt tatgtagact
    76141 acgccaaagg cttcgttcag ttgattgctc catttgctcc tcacttggca gaagagctct
    76201 ggcaaacagt tgcagcaaca ggagaatcta tctcttatgt agcttggcca acttgggatg
    76261 aaagcaaatt agttgaagac gaaatcgaaa tcgtcgtcca aatcaaaggt aaagtccgtg
    76321 ccaaactcat ggttgctaaa gacctgtcac gcgaagaatt gcaagaaatt gctctcgctg
    76381 atgaaaaagt caaggtagaa attgacggta aggaaatcgt gaaagtgatt gcggtaccta
    76441 acaaactcgt taatatcgtc gttaaataac gagtttatta gctctatctg ccaccttcaa
    76501 tagtccactg gactattgaa gccaactaaa ttggttaata ttgttgtgaa ataagatagg
    76561 aatccttcag agtagaatct gggggatttt ttgaatcttc ttatgaaagt atgttatact
    76621 atggtcaact ataaaatttg aaaagcgaaa caaggggaaa gttatgccag taaatgaata
    76681 tggtcagatg attggtgagt caatggaagg ttatacacct ggtgcactgc cttctattga
    76741 tttcttagaa gggcgttatg ctcgaataga agctctttca gtggaaaagc atgcggagga
    76801 tttattagct gtttatggcc ctgatacgcc tcgggaaatg tggacctacc tctttcagga
    76861 atcagtggca gatatggagg agctggttag ccttttaaat cagatgttgg ctcgtaagga
    76921 ccgtttttac tatgcaatca tagacaaggc aactggtaag gctttgggaa ctttttctct
    76981 catgcgtatt gaccagaata atcgagtaat agaagtggga gctgtcactt tttctccaaa
    77041 actcaggggg acacggatag ggacagaagc ccagtatcta ctggcgcgct atgtctttga
    77101 agagcttaac tatcgtcgct atgagtggaa atgtgattct cttaatctgc catccagacg
    77161 agcagcggaa cgtttgggat ttgtctatga aggaaccttc cgtcaggcag tggtttataa
    77221 ggggcgtacg agggatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
    77281 agctcgattg gaagcatggc tgactcctga aaattttgat aaaactgggc aacaatacaa
    77341 gagtttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
    77401 aagctagagg atgttttgca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
    77461 ccagagatgc tggagcaggc cttatctcat tcattagtga tttatgtggc gcttgatggt
    77521 gatgctgtag tgggcttgat tcgtttggtt ggagatggtt tttcatcagt ttttgtacag
    77581 gatttgattg ttttgcctaa ctatcagcgc caagggattg gtagtctctt gatgaaagag
    77641 gctttaaaag attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaaa
    77701 aacgtaagat tttatcgttc tatgggtttt gaagccttat ccacctatga ttgtatagga
    77761 atgacttggg tgaatcgaga aaaataacaa aacttgtttt ttcttaagca aagtttaagg
    77821 atggtctagt atcatatagt cattaaataa agacctccta actttattta ataaaatcct
    77881 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
    77941 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
    78001 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
    78061 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
    78121 ttttttagct ctatttcagg atttttggga ctattctaaa aataattttt cgatattttt
    78181 cggtattttt cggattttgg tcggggaatt ggcggggact ttttgagatt ttggagggga
    78241 tttttttagc gaatatgact aagaaatagg tctgtggtcg cttcagctag ttcaaactca
    78301 atttgattgt aagtgactgt taattgaagg actggaacta ctgtaataat gattttgctt
    78361 gtctagtagt ggcgtattaa atgaaaagtg acatgtaaga ttgtctcttc gtttacgaaa
    78421 tcaaaatttc tatgaaattg atagaatccc taacgttctc ttaattttaa ccgtcttgtc
    78481 gtacagcggt tgaagaaaat gtaaaccttt gacaaaattc gtgaactatg ggataataaa
    78541 aaggaattga gtactagttc tatatcatag gctagaaaag accccaagct cacgaccaaa
    78601 taagcttgag gtcttttttg acactatttg tccttgttta gccatttatc gactatacga
    78661 agaacgacac cgaccacaat tggtccgatg atagttttga gtactaattc catcatgggc
    78721 tatctcacct cctttcgtag gcggtgtaga agtgccgtat aatattatac cacataagtg
    78781 ctaaacttag gagtcaccca atcaggtggc ttttttgttt gtggcttggt tttttgatat
    78841 aatagagcca tgggtagaat tttagataat gagataatgg gggatgagga gttagtagaa
    78901 cgcacgctcc gtcctcagta tttacgtgaa tatatcggac aggataaggt caaggaccag
    78961 ctacaaatct ttattgaagc tgcaaaaatg cgggatgaag cgctggatca tgtgctctta
    79021 tttgggcctc caggtctcgg gaaaacgacc atggcctttg ttattgccaa cgaactggga
    79081 gtcaatctta agcagacgtc gggtccagtc attgaaaaag ccggagatct ggtagctatt
    79141 ttgaatgagt tagagcctgg ggatgtcctt tttattgatg agatccatcg tttgccaatg
    79201 tcagtggaag aggtgcttta tagtgctatg gaggacttct acatagatat tatgattggg
    79261 gctggtgaag gcagtcgcag tgttcatttg gagttgcctc cttttacctt gattggtgcg
    79321 acgactcggg ctggtatgct ctcaaatcca ctacgggcac gttttgggat tacaggtcat
    79381 atggagtatt atgcccatgc tgacttgaca gaaattgtcg agcggacggc agatattttt
    79441 gagatggaaa tcactcatga ggcagcatct gagttggccc tacgtagtcg tggaacccct
    79501 cgtattgcca atcgtctcct caagcgcgtg cgcgattttg cccagataat ggggaatggg
    79561 gtaatcgatg atattattac cgataaggct ttgactatgc tggatgttga ccatgaaggt
    79621 ttggactatg tggatcaaaa aatccttcgt accatgattg agatgtacag tggaggacct
    79681 gttggtctag gaactctttc tgtcaatatc gccgaagagc gtgagacagt tgaagacatg
    79741 tatgagcctt acttgattca aaaaggtttt atcatgcgga cacggtctgg acgggtggcg
    79801 actgctaagg catatgagca cttaggttat gaatacagtg aaaaataagc aagaaatctt
    79861 agaggctttt agagaaaatc cagatatgat ggccattctg acgatcatcc gagaccttgg
    79921 tttgaaagac tcgtagttgg cagcaggttc tgtcagaaat ttcatctgga atcttttgtc
    79981 agacaaatcc ccttttgatc atgaaacaga tatagatgtg attttctttg atccagattt
    80041 ttcttatgag gaaaccttat tactggagaa aaagctgaga gaggattttc ctcagtacca
    80101 gtgggaattg aaaaatcagg tctatatgca ccagcacagt cctcacactg ctttctatac
    80161 cagttctcgt gatgctatga gtaagtatcc agaacggtgt acggcagttg gactgcgctt
    80221 gaatgaagaa tcagattttg aactttatgc accttatggt ttggaggata ttttgaattt
    80281 tcaagttcgt ccaactcctc atttcttaga aaatgaagac cgaatggaac tctatcaaac
    80341 acgtttatcc aagaaaaatt ggcaggagaa atggaaaaat ttgattttta aaaatactta
    80401 aggaaacttt aagctaggga gtgtacacta agttcataag ttaagaagac cttaacttaa
    80461 actcctaaaa ctttttcata ataatctccc tataaaaata aagtcgccca atcaggcggc
    80521 ttattttttt gaaaaatggg catggtgcct gagaataaat agcttagtga tagaagaaaa
    80581 tggggaaata tggtataatg aaacgataga tttttgaata ggaataagat catgtttgga
    80641 ttttttaaga aagataaggc tgtggaagta gaggttccga cacaggttcc tgctcatatc
    80701 ggcatcatca tggatggcaa tggccgttgg gctaaaaaac gtatgcaacc gcgagttttt
    80761 ggacataagg cgggcatgga agcattgcaa accgtgacca aggcagccaa caaactgggc
    80821 gtcaaggtta ttacggtcta tgctttttct acggaaaact ggacccgtcc agatcaggaa
    80881 gtcaagttta tcatgaactt gccagtagag ttttatgata attatgtccc ggaactacat
    80941 gcgaataatg ttaagattca aatgattggg gagacagacc gcctgcctaa gcaaaccttt
    81001 gaagctttaa ccaaggctga ggaattgact aagaacaaca caggattgat tcttaatttt
    81061 gctcttaact atggtggacg tgctgagatt acacaggcgc ttaagttgat ttcccaggat
    81121 gttttagatg ccaaaatcaa tccaggtgac atcacagagg aattgattgg taactatctc
    81181 tttacccagc atttgcctaa ggacttacga gacccagact tgattatccg tactagtgga
    81241 gaattacgtt tgagcaattt ccttccatgg cagggagcct atagtgagct ttattttacg
    81301 gacaccttat ggcctgattt tgacgaagcg gccttgcagg aagctattct tgcctataat
    81361 cgtcgtcatc gccgatttgg aggagtttag gaggaaatat gacccaggat ttacagaaaa
    81421 gaaccttgtt tgcagggatt gccctggcta ttttcctacc aattttaatg attgggggcc
    81481 tcttgcttca gatagcaatc ggaatcatag ccatgctagc catgcatgaa cttttgaaga
    81541 tgagaggtct agagaccatg acgatggagg gcctcttgac cctctttgca acctttgcat
    81601 tgaccattcc cttggagaat tacctgactt ttttgccagt tgatgggaat gtggttgcct
    81661 atagtgtttt gatttcaatc atgttaggaa cgaccgtttt tagcaagtct tatacgattg
    81721 aggatgcggt tttccctctt gctatgagct tctacgtggg ctttggattt aatgctttac
    81781 tagatgctcg tgttgcaggt ttggacaagg ctctcttagc cttgtgtatc gtctgggcga
    81841 cagacagtgg tgcctatctt gttgggatga actatgggaa acgaaagtta gcaccaaggg
    81901 tatcgcctaa taaaaccctt gagggtgcct tgggtggtat tttaggagca attttagtaa
    81961 ccattatctt tatgatagtt gacagtacag ttgctcttcc atatggaatt tacaagatgt
    82021 cagtctttgc tattttcttt agcattgctg gacaatttgg tgatttacta gaaagttcga
    82081 tcaaacgtca ttttggtgtt aaggattctg ggaaatttat ccctggacat ggtggtgttt
    82141 tggatcgttt cgatagtatg ttgcttgtat ttccaatcat gcacttattt ggactctttt
    82201 aatcaaaaga cggaggaaac gctatgctcg gaattttaac ctttattctg gttttcggga
    82261 ttattgtagt ggtgcacgag ttcgggcact tctactttgc caagaaatca gggattttag
    82321 tacgtgaatt tgccatcggt atgggaccta aaatttttgc tcacattggc aaggatggaa
    82381 cggcctatac cattcgaatc ttgcctctgg gtggctatgt ccgcatggcc ggttggggtg
    82441 atgatacaac tgaaatcaag acaggaacgc ctgttagttt gacacttgct gatgatggta
    82501 aggttaaacg catcaatctc tcaggtaaaa aattggatca aacagccctc cctatgcagg
    82561 tgacccagtt tgattttgaa gacaagctct ttatcaaagg attggttctg gaagaagaaa
    82621 aaacatttgc agtggatcac gatgcaacgg ttgtggaagc agatggtact gaggttcgga
    82681 ttgcaccttt agatgttcaa tatcaaaatg cgactatctg gggcaaactg attaccaatt
    82741 ttgcaggtcc tatgaacaat tttatcttag gtgtcgttgt tttttgggtt ttaatcttta
    82801 tgcagggtgg tgtcagagat gttgatacca atcagttcca tatcatgccc caaggtgcct
    82861 tggccaaggt aggagtacca gaaacggcac aaattaccaa gattggctca catgaggtta
    82921 gcaactggga aagcttgatc caagctgtgg aaacagaaac caaagataag acggcaccga
    82981 ctttggatgt gactatttct gaaaagggga gtgacaaaca agtcactgtt acacccgaag
    83041 atagtcaagg tcgttacctt ctaggtgttc aaccgggggt taagtcagat tttctatcca
    83101 tgtttgtagg tggttttaca actgctgctg actcagctct ccgaattctc tcagctctga
    83161 aaaatctgat tttccaaccg gatttgaaca agttgggtgg acctgttgct atctttaagg
    83221 caagtagtga tgctgctaaa aatggaattg aaaatatctt gtacttcttg gcaatgattt
    83281 ccatcaatat tgggattttt aatcttattc cgattccagc cttggatggt ggtaagattg
    83341 tgctcaatat cctagaagcc atccgccgca aaccattgaa acaagaaatt gaaacctatg
    83401 tcaccttggc cggagtggtc atcatggttg tcttgatgat tgctgtgact tggaatgaca
    83461 ttatgcgact cttttttaga taatcgagga atattatgaa acaaagtaaa atgcctatcc
    83521 caacgcttcg cgaaatgcca agcgatgctc aagttatcag ccatgctctt atgttgcgtg
    83581 ctggttatgt tcgccaagtt tcagcaggtg tttattctta tctaccactt gccaaccgtg
    83641 tgattgaaaa agctaaaaac atcatgcgcc aagaattcga aaagattggt gctgttgaga
    83701 tgttggctcc tgcccttctt agtgcagaat tgtggcgtga atcaggtcgt tacgaaacct
    83761 atggtgaaga cctttacaaa ctaaaaaacc gtgaaaaatc agactttatc ttaggtccaa
    83821 ctcacgaaga aacctttaca gctattgtcc gtgattctgt taaatcttac aagcaattgc
    83881 cactcaacct ttatcaaatt cagcccaagt atcgtgatga aaaacgcccg cgtaatggac
    83941 ttcttcgtac acgtgagttt atcatgaagg atgcttatag tttccacgct aactatgata
    84001 gtttggatag tgtttatgat gagtacaaag cagcctatga gcgtattttc actcgtagtg
    84061 gtttagactt caaggctatt attggtgacg gtggagccat gggtggtaag gatagccaag
    84121 aatttatggc cattacatct gctcgtacag accttgaccg ctgggttgtc ttggacaagt
    84181 cagttgcctc atttgacgaa attcctgcag aagtgcaaga agaaatcaag gcagaattgc
    84241 tcaaatggat agtctctggt gaagatacca ttgcttactc aagtgagtct agctatgcag
    84301 ctaacttaga aatggcaaca aacgagtaca aaccaagcaa ccgtgttgtc gctgaagaag
    84361 aagttactcg tgttgcaacg ccagatgtta aatcaattga tgaagttgca gccttcctca
    84421 atgttccaga agaacaaacg attaaaaccc tcttctacat tgcagatggc gagcttgttg
    84481 cagcccttct agttggaaat gaccaactca acgaagtcaa gttgaaaaat cacttgggag
    84541 cagatttctt tgacgttgct agcgaagaag aagtggcgaa tgttgttcaa gcaggatttg
    84601 gttcacttgg accagttggt ttgccagaga atattaaaat tattgcagat cgtaaggtac
    84661 aagatgttcg caatgcagtt gtcggtgcta acgaagatgg ctaccacttg actggtgtga
    84721 acccaggccg tgattttact gcagaatatg tggatatccg tgaagttcgt gagggtgaaa
    84781 tttccccaga tggacaaggt gtccttaact ttgcgcgtgg tattgagatc ggtcatattt
    84841 tcaaactcgg aactcgctat tcagcaagca tgggagcaga tgtcttggat gaaaatggtc
    84901 gtgctgtgcc aatcatcatg ggatgttacg gtatcggtgt cagccgtctt ctttcagcag
    84961 tgatggagca acacgctcgc ctctttgtta acaaaacgcc aaaaggtgaa taccgttacg
    85021 cttggggaat caatttccct aaagaattgg caccatttga tgtgcatttg attactgtca
    85081 atgtcaagga tgaagaagcg caagccttga cagaaaaact tgaagcaagc ttgatgggag
    85141 ctggttatga agtcttgaca gatgaccgta acgaacgtgt cggtgttaaa tttagcgata
    85201 gtgacttgat tggtcttcca atccgtatca ctgttggtaa aaaagcggcc gatggcattg
    85261 tagaagttaa gatcaaggca actggtgaca ccattgaggt tcatgcagat aacgtgcttg
    85321 aaacgcttga aatcctaagc aagaaataaa aactataatc agaagaaaaa caaggaaaaa
    85381 atgtaactag tttttacctt gttttttctg tataatggga gaaatgagta gataaagagg
    85441 taaatgtatg ctaagatttc caaaggattt tgtctgggga tcctctactt ctggaccgca
    85501 gacagaagga cgtgtagctg gtgacggtaa gggagacaat ctctgggatt actggttcca
    85561 agtggagcca aatcgttact ataatgggat tggttcagat aagacatcga ctttttatga
    85621 aaattgggag cgggatattg agcttttgtt agagactggt cacacagcct ttcggacttc
    85681 tattcagtgg tcacggattt ttccacaagg ctgtggaaaa gtcaaccctc aaggtgtgga
    85741 tttttatcgt aaggtctttg aggctattaa ggctaaagga attcgtctgt tagtcaatct
    85801 ctatcatttt gatttacctt ttgcccttca agaggatggt gatggttggg aaaataaggc
    85861 gacagtctca gcctatgaag actatgctcg tttttgtttt gagacttatg gagatttagt
    85921 ggatcaatgg attaccttta acgagcccat cgttcctgta gaatttggtt atttttatga
    85981 tgcccattat ccacataagg tggatgcaga ggcagctgtt aaggtagcct atcatacaca
    86041 attggccagc agccgggctg ttaaggcttg ccatgaactt ttgcctgatt ccaagattgg
    86101 gattgtcctc aacttgacac cggcttatcc acgtagccag catcctgctg atgtcaaggc
    86161 agctcgtatt gcggcccttt ttcaggccca atctttctta gatccatctg tcttggggac
    86221 ttatccacag gagttggtag aaatcttgca tgaacacggt cttttacctg atgctacaga
    86281 ggaagagttg gaactcattc gtgataatac ggtggacttc cttggtgtga actactatca
    86341 acctttgcgt gttatggctc ctcgatttgc taagcatcca gatagtccac tcttaccaga
    86401 acatttttac gagccttatg tgatgcctgg acgtaaaatc aattctcacc gtggttggga
    86461 gatttatgag caagggattt atgacatcgc ccaaaatatc aaggaaaatt atgacaatat
    86521 tgaatggatg ttgactgaga atggtatggg tgttgaaggg gaagaaaaat tccgtcaaga
    86581 tggaatgatt caagatgatt accgtattga ctttgtaaaa ggtcatcttc gtgaacttca
    86641 ccgtgccatt gaagatggtg ccaactgtaa gggctacttg atttggacct ttattgactg
    86701 ctggtcatgg ctcaacagct ataaaaatcg ctatggtttg gtcgaattag acttggaaac
    86761 gcaagaacgt cgtctgaaga aatcaggcca ctggttcaaa gaattaagcg ataataatgg
    86821 attttaaaaa ggactctgac tgattatccc aatcggtcag agttttttgc ttacaggagc
    86881 ttaatttgaa ctataccaat ttttactctt gacaagtgaa agaaacaagt atatactgtt
    86941 tttgctgatt ctataaaaga tgaattagac tataccaatt ttaaggagaa agcacagctt
    87001 gcctgtgtcg tatatactat gtgtggaatt gttggtgttg ttggaaacac aaatgcaact
    87061 gatattttga ttcaagggct tgaaaagctt gaataccgtg gctatgattc tgcgggaatt
    87121 tttgtcctag atggtgctga taaccatttg gtgaaggctg ttggtcgtat cgcagaattg
    87181 tctgccaaga cagctggtgt tgagggaaca actggtatcg gacatactcg ttgggcaact
    87241 catgggaaac caacggaaga caatgctcac ccacaccgct ctgagacaga acgttttgtc
    87301 ttggttcaca atggggtgat tgaaaactac cttgaaatta aagaagaata ccttgctggg
    87361 caccacttca aagggcaaac agatacggaa atcgccgtac atttgattgg aaaatttgcg
    87421 gaagaagacg gtctctcagt tcttgaagcc tttaaaaaag ctcttcatat tatccgtggt
    87481 tcatatgcct ttgccttgat tgactctgaa aatccagatg tcatctatgt agcgaaaaac
    87541 aaatctccac ttttgattgg tcttggggaa ggctacaata tggtctgctc agatgctatg
    87601 gctatgattc gtgaaaccaa ccaatacatg gaaattcatg accaagagtt ggtaatcgtc
    87661 aaggctgata gcgtggaagt tcaagactat gatggtaaca gtcgtgaacg tgctagctat
    87721 actgcggaac ttgacttgtc agatatcggt aagggaactt atccttacta catgcttaag
    87781 gaaattgatg agcaaccaac tgttatgcgt aaactcattc aagcctacac ggatgatgct
    87841 ggtcaagtag tgattgatcc tgctatcatt aaggctgttc aagacgcaga ccgcatctac
    87901 atccttgcag ctggaacatc ttaccatgca ggatttgctt ctaagaaaat gttggaagaa
    87961 ttgacagata caccagttga acttggaatc tcatctgagt ggggctacgg tatgccactt
    88021 ctcagcaaga aaccactctt catctttatc agccaatctg gtgaaacagc ggatagtcgt
    88081 caagttttgg tcaaggctaa tgaaatggga attccaagct taacagtgac aaacgttcca
    88141 ggttcaaccc tctcacgtga agccaactat accatgctcc ttcacgcagg tcctgaaatt
    88201 gccgtggcat caactaaagc ctatacagcg caaatcgcag cccttgcctt ccttgcaaaa
    88261 gcagtcggag aagcaaatgg taatgctaaa gcgcaagcct ttgacctggt tcatgaattg
    88321 tcaatcgtag ctcagtctat cgaatcaact ctttcagaga aagaaaccat tgaagccaag
    88381 gttcgtgaac ttcttgaaac aactcgtaac gccttttaca tcggacgtgg tcaagattac
    88441 tacgtagcca tggaagcaag tctcaaactc aaagagattt cttatatcca gtgtgaaggt
    88501 tttgcggcag gagaactcaa gcacggaacc attgccttga ttgaagaagg aacgcctgtc
    88561 ttgtctctct tgtcagatcc agttcttgcc aaccatactc gtggaaatat ccaagaggtc
    88621 gcagcccgtg gtgccaaagt cctcactatc gcagaagaga atgtagccaa agataccgac
    88681 gatatcgtcc ttacgaccgt acatccatac ctctcaccaa tttcaatggt cgtaccaacg
    88741 caattagtcg cttactttgc aaccctccac cgtggcctcg atgtggacaa accacgtaac
    88801 cttgccaagt cagtaacggt agaataagct aaaaaagtct agttatctag gcctttttct
    88861 tgtgagcaaa ttggttgctt gtacttaaga ttcgtgttag aataattttt caaattgaag
    88921 gacagagata gacaaggaga atcacaatgg tagaattggg aatttcaaca tttggggaaa
    88981 taacggagct tgaagggact ggacaaactt acagtcatgc tgaacgcatt cgccagttgg
    89041 tggcagagat tgagctggct gacaagattg gtttggacgt atatgggatt ggcgagcacc
    89101 atcgggcgga ttttgcagta tcagccccag agattgtcct ggccgctggg gcagtcaata
    89161 ccaagaaaat ccgtttgacc agtgcagtca gcattctgtc aagcatggat ccgattcgtt
    89221 tgttccaaca gtatgccact atcgatgctt tgtcaaatgg acgatcggag attatggctg
    89281 gaaggggctc tttcacggaa tctttccctc tgtttggtta tgacttgaaa gactacgact
    89341 ctctttttga tgagaaatta gacttgcttc agttagtcaa tgaaaagacc aagttagact
    89401 ggcaaggtcg attgactcaa acgattgctg gtaaagaagt ttatcctcgt ccagttcagg
    89461 acaaattgcc cttgtggata gctacaggtg gtcatgtcga atcaacagtg aagattgctc
    89521 aggctggtct accgattgta tatgctatta ttggtggtaa tccacgttat tttaaaaagt
    89581 tgattcaggc ttatcgtgag attggaagcg aagcgggcca tgctgacaaa gacttgaaag
    89641 tgggagccca ttcttggggg tggattgcgg aagatggtga gcaggcggtg aaagattatt
    89701 tccatccgac taagcaagta gtggatgcta tttccaaaga ccgtccgcac tggcaggaat
    89761 tgcgttatga gcaatatttg gagcaggtag ggccaaatgg cgccatgttt gttggcaatc
    89821 cagatcaggt ggccgaaaaa ttgattcgca tgatagagga tttaggattg gaccgcttca
    89881 tgcttcatct accgcttggt tctatgcctc atgaccaggt tctgagagct attgaactct
    89941 tcggaacaca agttgcaccc aaagtacgag cttattttgc tatgaaagag gcttaataaa
    90001 aaatcctaat caagtttatt aggacaacaa atattgtacg aaaattaa
//
LOCUS       DBEROT010000004        83194 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.04, whole genome shotgun sequence.
ACCESSION   DBEROT010000004 DBEROT010000000
VERSION     DBEROT010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 83194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.04"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            434..661
                     /locus_tag="ACL8CG_000307"
     CDS             434..661
                     /locus_tag="ACL8CG_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342970.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            949..3846
                     /gene="nanA"
                     /locus_tag="ACL8CG_000308"
     CDS             949..3846
                     /gene="nanA"
                     /locus_tag="ACL8CG_000308"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGS1342971.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKEDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4861..5313
                     /locus_tag="ACL8CG_000309"
     CDS             4861..5313
                     /locus_tag="ACL8CG_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS1342972.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGDFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5332..6669
                     /locus_tag="ACL8CG_000310"
     CDS             5332..6669
                     /locus_tag="ACL8CG_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1342973.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6748..7632
                     /locus_tag="ACL8CG_000311"
     CDS             6748..7632
                     /locus_tag="ACL8CG_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1342974.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7632..8465
                     /locus_tag="ACL8CG_000312"
     CDS             7632..8465
                     /locus_tag="ACL8CG_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1342975.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8483..10576
                     /gene="nanB"
                     /locus_tag="ACL8CG_000313"
     CDS             8483..10576
                     /gene="nanB"
                     /locus_tag="ACL8CG_000313"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGS1342976.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10588..11691
                     /locus_tag="ACL8CG_000314"
     CDS             10588..11691
                     /locus_tag="ACL8CG_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS1342977.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11865..12563
                     /locus_tag="ACL8CG_000315"
     CDS             11865..12563
                     /locus_tag="ACL8CG_000315"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS1342978.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12582..14099
                     /locus_tag="ACL8CG_000316"
     CDS             12582..14099
                     /locus_tag="ACL8CG_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS1342979.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14224..15552
                     /locus_tag="ACL8CG_000317"
     CDS             14224..15552
                     /locus_tag="ACL8CG_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1342980.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15804..16670
                     /locus_tag="ACL8CG_000318"
     CDS             15804..16670
                     /locus_tag="ACL8CG_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1342981.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16686..17525
                     /locus_tag="ACL8CG_000319"
     CDS             16686..17525
                     /locus_tag="ACL8CG_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1342982.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLVGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17798..18250
                     /locus_tag="ACL8CG_000320"
     CDS             17798..18250
                     /locus_tag="ACL8CG_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS1342983.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRRDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKEEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18347..18691
                     /locus_tag="ACL8CG_000321"
     CDS             18347..18691
                     /locus_tag="ACL8CG_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342984.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            18701..18895
                     /locus_tag="ACL8CG_000322"
     CDS             18701..18895
                     /locus_tag="ACL8CG_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1342985.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLSGI
                     YIDYMSIDKSRKKSKRKKKK"
     gene            18978..19622
                     /locus_tag="ACL8CG_000323"
     CDS             18978..19622
                     /locus_tag="ACL8CG_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS1342986.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19791..20708
                     /locus_tag="ACL8CG_000324"
     CDS             19791..20708
                     /locus_tag="ACL8CG_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGS1342987.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20726..21610
                     /locus_tag="ACL8CG_000325"
     CDS             20726..21610
                     /locus_tag="ACL8CG_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS1342988.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21626..22477)
                     /locus_tag="ACL8CG_000326"
     CDS             complement(21626..22477)
                     /locus_tag="ACL8CG_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGS1342989.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22677..24734
                     /gene="pbp2b"
                     /locus_tag="ACL8CG_000327"
     CDS             22677..24734
                     /gene="pbp2b"
                     /locus_tag="ACL8CG_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGS1342990.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24745..25341
                     /gene="recR"
                     /locus_tag="ACL8CG_000328"
     CDS             24745..25341
                     /gene="recR"
                     /locus_tag="ACL8CG_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGS1342991.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25517..26560
                     /locus_tag="ACL8CG_000329"
     CDS             25517..26560
                     /locus_tag="ACL8CG_000329"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGS1342992.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26644..28017
                     /gene="murF"
                     /locus_tag="ACL8CG_000330"
     CDS             26644..28017
                     /gene="murF"
                     /locus_tag="ACL8CG_000330"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGS1342993.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTVIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLFLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAVNGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENEAK"
     gene            28004..28615
                     /locus_tag="ACL8CG_000331"
     CDS             28004..28615
                     /locus_tag="ACL8CG_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGS1342994.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDVEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28706..29410
                     /locus_tag="ACL8CG_000332"
     CDS             28706..29410
                     /locus_tag="ACL8CG_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGS1342995.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHVTILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29629..31002
                     /gene="ftsA"
                     /locus_tag="ACL8CG_000333"
     CDS             29629..31002
                     /gene="ftsA"
                     /locus_tag="ACL8CG_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGS1342996.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            31019..32278
                     /gene="ftsZ"
                     /locus_tag="ACL8CG_000334"
     CDS             31019..32278
                     /gene="ftsZ"
                     /locus_tag="ACL8CG_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGS1342997.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32283..32954
                     /locus_tag="ACL8CG_000335"
     CDS             32283..32954
                     /locus_tag="ACL8CG_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGS1342998.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32964..33503
                     /locus_tag="ACL8CG_000336"
     CDS             32964..33503
                     /locus_tag="ACL8CG_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGS1342999.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33503..33766
                     /locus_tag="ACL8CG_000337"
     CDS             33503..33766
                     /locus_tag="ACL8CG_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGS1343000.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33763..34548
                     /locus_tag="ACL8CG_000338"
     CDS             33763..34548
                     /locus_tag="ACL8CG_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGS1343001.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34557..35345
                     /gene="divIVA"
                     /locus_tag="ACL8CG_000339"
     CDS             34557..35345
                     /gene="divIVA"
                     /locus_tag="ACL8CG_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGS1343002.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35693..38485
                     /gene="ileS"
                     /locus_tag="ACL8CG_000340"
     CDS             35693..38485
                     /gene="ileS"
                     /locus_tag="ACL8CG_000340"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGS1343003.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            39042..39404
                     /locus_tag="ACL8CG_000341"
     CDS             39042..39404
                     /locus_tag="ACL8CG_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343004.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNTLKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            39940..40632
                     /locus_tag="ACL8CG_000342"
     CDS             39940..40632
                     /locus_tag="ACL8CG_000342"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGS1343005.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            40685..43096
                     /locus_tag="ACL8CG_000343"
     CDS             40685..43096
                     /locus_tag="ACL8CG_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS1343006.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRYCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            43346..44047
                     /locus_tag="ACL8CG_000344"
     CDS             43346..44047
                     /locus_tag="ACL8CG_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343007.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            44049..46757
                     /locus_tag="ACL8CG_000345"
     CDS             44049..46757
                     /locus_tag="ACL8CG_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS1343008.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEN
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(46853..47344)
                     /gene="tpx"
                     /locus_tag="ACL8CG_000346"
     CDS             complement(46853..47344)
                     /gene="tpx"
                     /locus_tag="ACL8CG_000346"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGS1343009.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(47467..48396)
                     /gene="psaA"
                     /locus_tag="ACL8CG_000347"
     CDS             complement(47467..48396)
                     /gene="psaA"
                     /locus_tag="ACL8CG_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGS1343010.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(48428..49276)
                     /locus_tag="ACL8CG_000348"
     CDS             complement(48428..49276)
                     /locus_tag="ACL8CG_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGS1343011.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(49273..49995)
                     /locus_tag="ACL8CG_000349"
     CDS             complement(49273..49995)
                     /locus_tag="ACL8CG_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS1343012.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            50286..52178
                     /gene="pepO"
                     /locus_tag="ACL8CG_000350"
     CDS             50286..52178
                     /gene="pepO"
                     /locus_tag="ACL8CG_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGS1343013.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEERSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(52301..52930)
                     /locus_tag="ACL8CG_000351"
     CDS             complement(52301..52930)
                     /locus_tag="ACL8CG_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS1343014.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAYLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            53887..56109
                     /locus_tag="ACL8CG_000352"
     CDS             53887..56109
                     /locus_tag="ACL8CG_000352"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGS1343015.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            56139..56582
                     /gene="dtd"
                     /locus_tag="ACL8CG_000353"
     CDS             56139..56582
                     /gene="dtd"
                     /locus_tag="ACL8CG_000353"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGS1343016.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(57199..57849)
                     /locus_tag="ACL8CG_000354"
     CDS             complement(57199..57849)
                     /locus_tag="ACL8CG_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGS1343017.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            57961..58803
                     /locus_tag="ACL8CG_000355"
     CDS             57961..58803
                     /locus_tag="ACL8CG_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1343018.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            58879..59316
                     /locus_tag="ACL8CG_000356"
     CDS             58879..59316
                     /locus_tag="ACL8CG_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGS1343019.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRN
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            59384..59635
                     /locus_tag="ACL8CG_000357"
     CDS             59384..59635
                     /locus_tag="ACL8CG_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343020.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLK"
     gene            complement(59777..60850)
                     /locus_tag="ACL8CG_000358"
     CDS             complement(59777..60850)
                     /locus_tag="ACL8CG_000358"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGS1343021.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLELAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            61006..61683
                     /locus_tag="ACL8CG_000359"
     CDS             61006..61683
                     /locus_tag="ACL8CG_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1343022.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            61676..62650
                     /locus_tag="ACL8CG_000360"
     CDS             61676..62650
                     /locus_tag="ACL8CG_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGS1343023.1"
                     /translation="MLDWKQFFLAYLRSRSRLFVYLLSLAFLVLLFQFLFASLGIYFL
                     YFFLLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(62699..64642)
                     /gene="thrS"
                     /locus_tag="ACL8CG_000361"
     CDS             complement(62699..64642)
                     /gene="thrS"
                     /locus_tag="ACL8CG_000361"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGS1343024.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(64700..64876)
                     /locus_tag="ACL8CG_000362"
     CDS             complement(64700..64876)
                     /locus_tag="ACL8CG_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGS1343025.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMKNF
                     LSDKEKQLNVRTRK"
     gene            complement(64883..65023)
                     /locus_tag="ACL8CG_000363"
     CDS             complement(64883..65023)
                     /locus_tag="ACL8CG_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGS1343026.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(65454..65654)
                     /locus_tag="ACL8CG_000364"
     CDS             complement(65454..65654)
                     /locus_tag="ACL8CG_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343027.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIISLLYSYRFRFSL"
     gene            65893..66522
                     /locus_tag="ACL8CG_000365"
     CDS             65893..66522
                     /locus_tag="ACL8CG_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1343028.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            66663..66932
                     /gene="rpsO"
                     /locus_tag="ACL8CG_000366"
     CDS             66663..66932
                     /gene="rpsO"
                     /locus_tag="ACL8CG_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGS1343029.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            67746..68360
                     /locus_tag="ACL8CG_000367"
     CDS             67746..68360
                     /locus_tag="ACL8CG_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGS1343030.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(68652..69401)
                     /locus_tag="ACL8CG_000368"
     CDS             complement(68652..69401)
                     /locus_tag="ACL8CG_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGS1343031.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTNKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            69534..71870
                     /locus_tag="ACL8CG_000369"
     CDS             69534..71870
                     /locus_tag="ACL8CG_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS1343032.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFSRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            71972..72649
                     /locus_tag="ACL8CG_000370"
     CDS             71972..72649
                     /locus_tag="ACL8CG_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGS1343033.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGCLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQNHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            72636..73433
                     /locus_tag="ACL8CG_000371"
     CDS             72636..73433
                     /locus_tag="ACL8CG_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGS1343034.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            73450..74553
                     /locus_tag="ACL8CG_000372"
     CDS             73450..74553
                     /locus_tag="ACL8CG_000372"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1343035.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            74560..74706
                     /locus_tag="ACL8CG_000373"
     CDS             74560..74706
                     /locus_tag="ACL8CG_000373"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343036.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVYRTDEVSNHTHGKATLTWFELD
                     FRRV"
     gene            74809..75828
                     /gene="galE"
                     /locus_tag="ACL8CG_000374"
     CDS             74809..75828
                     /gene="galE"
                     /locus_tag="ACL8CG_000374"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS1343037.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            75830..76795
                     /locus_tag="ACL8CG_000375"
     CDS             75830..76795
                     /locus_tag="ACL8CG_000375"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1343038.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(76846..77052)
                     /locus_tag="ACL8CG_000376"
     CDS             complement(76846..77052)
                     /locus_tag="ACL8CG_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGS1343039.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            77104..77580
                     /locus_tag="ACL8CG_000377"
     CDS             77104..77580
                     /locus_tag="ACL8CG_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGS1343040.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            77589..78260
                     /gene="cmk"
                     /locus_tag="ACL8CG_000378"
     CDS             77589..78260
                     /gene="cmk"
                     /locus_tag="ACL8CG_000378"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGS1343041.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            78391..78729
                     /locus_tag="ACL8CG_000379"
     CDS             78391..78729
                     /locus_tag="ACL8CG_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGS1343042.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDIVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            78732..79361
                     /locus_tag="ACL8CG_000380"
     CDS             78732..79361
                     /locus_tag="ACL8CG_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGS1343043.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            79601..80752
                     /locus_tag="ACL8CG_000381"
     CDS             79601..80752
                     /locus_tag="ACL8CG_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1343044.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKKASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            81065..81814
                     /gene="truA"
                     /locus_tag="ACL8CG_000382"
     CDS             81065..81814
                     /gene="truA"
                     /locus_tag="ACL8CG_000382"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGS1343045.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            81804..82577
                     /locus_tag="ACL8CG_000383"
     CDS             81804..82577
                     /locus_tag="ACL8CG_000383"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS1343046.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            82555..83016
                     /locus_tag="ACL8CG_000384"
     CDS             82555..83016
                     /locus_tag="ACL8CG_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1343047.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKFPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        24875 a        15120 c        18618 g        24581 t
ORIGIN      
        1 gtgttttgag ctgacttcgt cagttctatc tgccacctca aaacggtgtt ttgagctgac
       61 tttgtcagtc ttatctacaa cctcaaaaca gtgttttgag catcatgcgg ctagcttctt
      121 agtttgctct ttgattttca ttgagtataa aaacagatga gtttctgttt tctttttatg
      181 gactataaat gttcagctga aactactttc aaggacatta ttatataaaa gaattttttg
      241 aaactaaaat ctactatatt acactatatt gaaagcgttt taaaaataag gtataataaa
      301 tttactaaca cttataaaaa gtgatagaat ctatctttat gtatatttaa agatagattg
      361 ctgtaaaaat agtagtagct atgcgaaata acagatagag agaagggatt gaagcttaga
      421 aaaggggaat aatatgatat ttaaggcatt caagacaaaa aagcagagaa aaagacaagt
      481 tgaactactt ttgacagttt ttttcgacag ttttctgatt gatttatttc ttcacttatt
      541 tgggattgtc ccctttaagc tggataagat tctgattgtg agcttgatta tatttcccat
      601 tatttctaca agtatttatg cttatgaaaa gctatttgaa aaagtgttcg ataaggattg
      661 agcaggaagt atggtgtaaa tagcataggc tgatgtccat catttgctta taaagagata
      721 ttttagttta attgcagcgg tgccctggta gataaactag attggcagga gtctgattgg
      781 agaaaggaga ggggaaaatt ggcaccaatt tgagatagtt tgtttagttc atttttgtca
      841 tttaaatgaa ctgtagtaaa agaaagttaa taaaagacaa actaagtgca ttttctggag
      901 taaatgtctt atttcagaaa tcgggatata gatatagaga ggatcagtat gaatcggagt
      961 gttcaagaac gtaagtgtcg ttatagcatt aggaaactat cggtaggagc ggtttctatg
     1021 attgtaggag cagtggtatt tggaacgtct cctgttttag ctcaagaagg ggcaagtgag
     1081 caacctctgg caaatgaaac tcaactttcg ggggagagct caaccctaac tgatacagaa
     1141 aagagccagc cttcttcaga gactgaactt tctggcaata agcaagaaca agaaaggaaa
     1201 gataagcaag aagaaaaaat tccaagagat tactatgcac gagatttgga aaatgtcgaa
     1261 acagtgatag aaaaagaaga tgttgaaacc aatgcttcaa atggtcagag agttgattta
     1321 tcaagtgaac tagataaact aaagaaactt gaaaacgcaa cagttcacat ggagtttaag
     1381 ccagatgcat cagctccacg cttttacaat ctcttctctg tatccagtga caccaaggaa
     1441 gatgagtact tcactatggc agtttacaat aatactgcta ctctagaggg gcgtggttcg
     1501 gatgggaaac agttttacaa taattacaac gatgcaccct taaaagttaa accaggtcag
     1561 tggaattctg tgactttcac agttgaaaaa ccgacagcag aactacctaa aggccgagtg
     1621 cgcctctacg taaacggggt attatctcga acaagtctga gatctggcaa tttcattaaa
     1681 gatatgccag atgtaacgca tgtgcaaatc ggagcaacca agcgtgccaa caatacggtt
     1741 tgggggtcaa atctacagat tcggaatctc actgtgtata atcgtgcttt aacaccagaa
     1801 gaggtacaaa aacgtagtca actttttaaa cgctcagatt tagaaaaaaa actacctgaa
     1861 ggagcggctt taacagagaa aacggacata ttcgaaagcg ggcgtaacgg taacccaaat
     1921 aaagatggaa tcaagagtta tcgtattcca gcacttctca agacagataa aggaactttg
     1981 atcgcaggtg cagatgaacg ccgtctccat tcgagtgact ggggtgatat cggtatggtc
     2041 atcagacgta gtgaagataa tggtaaaact tggggtgacc gagtaaccat taccaactta
     2101 cgtgacaatc caaaagcttc tgacccatcg atcggttcac cagtgaatat cgatatggtg
     2161 ttggttcaag atcctgaaac caaacgaatc ttttctatct atgacatgtt cccagaaggg
     2221 aagggaatct ttggaatgtc ttcacaaaaa gaagaagcct acaaaaaaat cgatggaaaa
     2281 acctatcaaa tcctctatcg tgaaggagaa aagggagctt ataccattcg agaaaatggt
     2341 actgtctata caccagatgg taaggcgaca gactatcgcg ttgttgtaga tcctgttaaa
     2401 ccagcctata gcgacaaggg tgatctatac aagggtgacc aattactagg caatatctac
     2461 ttcacaacaa acaaaacttc tccatttaga attgccaagg atagctatct atggatgtcc
     2521 tacagtgatg acgacgggaa gacatggtca gcgcctcaag atattactcc gatggtcaaa
     2581 gccgattgga tgaaattctt gggtgtaggt cctggaacag gaattgtact tcggaatggg
     2641 cctcacaagg gacggatttt gataccggtt tatacgacta ataatgtatc tcacttaaat
     2701 ggctcgcaat cttctcgtgt catctattca gatgatcatg gaaaaacttg gcatgctgga
     2761 gaagcggtca acgataaccg tcaggtagac ggtcaaaaga tccactcttc tacgatgaac
     2821 aataaacgtg cgcaaaatac agaatcaacg gtggtacaac taaacaatgg agatgttaaa
     2881 ctctttatgc gtggtttgac tggagatctt caggttgcta caagtaaaga cggaggagtg
     2941 acttgggaga aggatatcaa acgttatcca caggttaaag atgtctatgt tcaaatgtct
     3001 gctatccata cgatgcacga aggaaaagaa tacatcatcc tcagtaatgc aggtggaccg
     3061 aaacgtgaaa atgggatggt ccacttagca cgtgtcgaag aaaatggtga gttgacttgg
     3121 ctcaaacaca atccaattca aaaaggagag tttgcctata attcgctcca agaattagga
     3181 aatggggagt atggcatctt gtatgaacat actgaaaaag gacaaaatgc ctatacccta
     3241 tcatttagaa aatttaattg ggaatttttg agcaaagatc tgatttctcc taccgaagcg
     3301 aaagtgaagc gaactagaga gatgggcaaa ggagagatgg gcaaaggagt tattggcttg
     3361 gagtttgact cagaagtatt ggtcaacaag gctccaaccc ttcaattggc aaatggtaaa
     3421 acagcgactt tcctaaccca gtatgatagc aaaaccttgt tgtttgcagt agataaggaa
     3481 gatatcggac aggaaattat tggtatagct aaaggaagca tcgaaagtat gcataatctt
     3541 cctgtaaatc tagcaggtgc cagagttcct ggcggagtaa atggtagcaa agcagcggtg
     3601 catgaagttc cagaatttac agggggagtt aatggtacag agccagctgt tcatgaaatc
     3661 gcagagtata agggatctga ttcgcttgta actcttacta caaaagaaga ttatacttac
     3721 aaagctcctc ttgctcagca ggcacttcct gaaacaggaa acaaggagag tgacctccta
     3781 gcttcactag gactaacagc tttcttcctt ggtctgttta cgctagggaa aaagagagaa
     3841 caataagaga agaattctaa acatttgatt ttgtaaaaat agaaggagat agcaggtttt
     3901 caagcctgct atcttttttt gatgacattc aagctgatac gaaatcataa gaggtctgaa
     3961 actactttca gagtagtctg ttctataaaa tatagtagat tgaaataaga tgtgaacaac
     4021 tctatcagga aagtcaaatt aatttataga aaaattttag cagtcaaggt gtactgttat
     4081 agattcaata tattatacga ctattaacct tatcttctcc taaaattgac tttcttgttt
     4141 tcttatcttg tccactcgaa acaagtattg taagaatttg attatttttg aaagtacttt
     4201 taatatactt gatatagtta aaaaagattt gaaactaaat tccaaattag aaaaagactt
     4261 gaaatactaa aaaaaaaaag tatactctaa ttgaaaacgg taacaaaact aatttagaga
     4321 atgaaatata gagtatttct ctcttaaaag tttttggtga aacgagatgt agaaaggaga
     4381 tttagccaaa gagtctatta gtgctagaat aatagattag aattatttta gaaaaacgaa
     4441 gtgagcagct tataaattca agtccccaaa tagattcata ctagtatctt ttgcaaaaaa
     4501 taaagggcga cttccttcat gaatatcaat ttcatctata aggaaggtag ctaattgaac
     4561 taacttattt attctgtttg tcgctagaaa aatcagacct ccttgtgaag attgaggaga
     4621 tacttaatga aaatcaaaga agaaactagc aagctagtag cagattgccc aaaacaccgc
     4681 tttgaggttg tagataagac tgacgtatat aatccaaggt gaagcgactg tggtttgaag
     4741 agattttcaa agagtataga ctagagagta gtgtttttat gtccttctag tagaaaatgc
     4801 tagacagaag aatggggaac ttggatagga aaaatagatt gagaaaggag gttagaagag
     4861 atgattatta caaaaattag ccgtttagga acttatgtgg gagtaaatcc acattttgca
     4921 acattaatag attttctaga aaaaacagga ctagaaaatt taacagaagg ttcgattgct
     4981 atcgatggta atcgattgtt tgggaattgc tttacttatc tagcagatgg tcaagcaggg
     5041 gatttctttg aaacacacca aaaatatttg gatattcatt tagttttgga aaacgaagaa
     5101 gccatggctg ttacatcgcc ggaaaatgta agcgttaccc aagaatatga tgaagagaaa
     5161 gatattgaat tatacacagg gaaagtggaa cagttggttc atttgagagc tggtgaatgc
     5221 ctcatcactt ttccagaaga tttacatcaa cccaaggttc gtataaatga tgaacctgtg
     5281 aaaaaagttg tctttaaagt tgcgatttct taatgtagaa agagaagaac gatgaaaaaa
     5341 atgagaaagt ttttatgtct agctggaatt gcgctagcgg ctgttgcctt ggtagcttgt
     5401 tcaggaaaaa aagaagctac aactagtact gaaccaccaa cagaattatc tggtgagatt
     5461 acaatgtggc actcctttac tcaaggaccc cgtttagaaa gtattcaaaa atcagcagat
     5521 gctttcatgc aaaagcatcc aaaaacgaaa atcaagattg aaacattttc ttggaatgac
     5581 ttctatacta aatggactac aggtttagca aatggaaatg tgccagatat cagtacagct
     5641 cttcctaacc aagtaatgga aatggtcaac tcagacgctt tggttccgct aaatgattct
     5701 atcaagcgta ttggacaaga taaatttaac gaaactgcct taaatgaagc aaaaatcgga
     5761 gatgattact actctgttcc tctttattca catgcacaag tcatgtgggt tagaacagat
     5821 ttgttaaaag aacataatat tgaggttcct aaaacttggg atcaactcta tgaagcttct
     5881 aaaaaattga aagaagctgg agtttatggc ttgtctgttc cgtttggaac aaatgactta
     5941 atggcaacac gtttcttgaa cttctacgta cgtagtggtg gaggaagcct cttaacaaaa
     6001 gatcttaaag cagacttgac aagccaactt gctcaagatg gtattaaata ctgggttaaa
     6061 ttgtataaag aaatctcacc tcaagattct ttgaacttta atgtccttca acaagctacc
     6121 ttgttctatc aaggaaaaac agcatttgac tttaactctg gcttccatat cggaggaatt
     6181 aatgccaaca gtcctcaatt gattgattcg attgatgctt atcctattcc aaaaatcaaa
     6241 gagtctgata aagatcaagg aattgaaacc tcaaacattc caatggttgt ttggaaaaat
     6301 tcaaaacatc cagaagttgc taaagcattc ttagaagcac tttataatga agaagactac
     6361 gttaaattcc ttgattcaac tccagtaggt atgttgccaa ctattaaggg gattagcgat
     6421 tctgcagcct ataaagaaaa tgaaactcgt aagaaattta aacatgctga agaagtaatt
     6481 actgaagctg ttaaaaaagg tactgctatt ggttatgaaa atggaccaag tgtacaagct
     6541 ggtatgttaa ctaaccaaca cattattgaa caaatgttcc aagatatcat tacaaatgga
     6601 acagatccta tgaaagcagc aaaagaagca gaaaaacaat taaatgattt atttgaggct
     6661 gttcagtaga tgtaaaagac tagaaaatag gtgggctagt gagctgaaaa gctctagccc
     6721 aatcttgtaa aagaagggag aaggagaatg gttaaagaac gtaatttaac tcgctggata
     6781 tttgttttgc cagctatgat tatcgtagga ttactctttg tttatccgtt tttctcgagt
     6841 attttttata gctttaccaa taagcatttg attatgccta attataaatt tgttggtttg
     6901 gctaactata aagctgtgct atcagatccc aacttcttta atgcgttctt taattcaatt
     6961 aagtggacca ttttctcatt agttggtcaa gttttagtag ggtttgtatt ggctttagct
     7021 cttcacagag tacgccactt caagaaatta tataggacct tattgattgt tccttgggca
     7081 tttcctacca tcgtcattgc cttttcttgg cagtggattc taaacggggt ttatggctac
     7141 ttacctaatc taatcgtaaa attaggttta atggaacata cacctgcatt tttgacagat
     7201 agtacatggg cattcctatg tttggtgttt atcaacattt ggtttggagc accaatgatt
     7261 atggttaatg tgctttcagc tttgcaaaca gtaccagaag aacaatttga ggctgctaag
     7321 atagatggtg cttcaagttg gcaggtgttc aagtttatcg tctttccaca tattaaagtg
     7381 gttgtaggac ttctagttgt tttgagaact gtatggatct ttaataactt tgacattatc
     7441 tacctcatta ctggtggtgg accagccaat gctacaacga cgcttccaat ttttgcttac
     7501 aacctgggct ggggaactaa attgttgggt cgtgcttcag cagttacagt attgctcttt
     7561 atcttcttgg tggcgatttg ctttatctac tttgctatca tcagtaagtg ggaaaaggag
     7621 ggtagaaaat aatgaagaag aaatccagta tttatttaga tattctctca catgtacttt
     7681 tagttggtgc gaccatcgtt gcaattttcc cattggtatg gattatcata tcttctgtca
     7741 aagggaaagg ggaattaact cagtatccaa cacgattttg gcctgaacag tttacattag
     7801 attatttcac tcatgttatc aacgatttgc acttcattga taacattcga aacagtttaa
     7861 tcattgcctt ggctacaacc ctcattgcga ttattatttc tgctatggca gcctatggta
     7921 ttgttcgatt ctttcctaaa ttgggagcaa tcatgtcgag actactcgtc attacctaca
     7981 ttttcccacc aattttgtta gcaattccct attcaattgc cattgctaaa gttgggttaa
     8041 caaatagttt atttggcttg atgatggttt atctatcttt tagtgttcca tatgcagttt
     8101 ggctcttagt tggatttttc caaacagttc caattggaat tgaagaagcg gctagaattg
     8161 atggtgcaaa taaatttgtt acgttttata aagttgtgct accgattgta gcaccaggta
     8221 ttgtagcaac agctatttat acatttatca atgcttggaa tgaattcctg tatgccttga
     8281 ttttgattaa caatacagga aagatgacag tagcagtagc ccttcgttca cttaatggtt
     8341 cagaaatact agactgggga gatatgatgg cagcgtctgt tattgtagtt cttccatcaa
     8401 ttattttctt ctctatcatc caaaataaga ttgcaagtgg attatcagaa ggatctgtga
     8461 agtagacgaa agaaggaaaa aaatgaataa aagaggtctt tattcaaaac taggaatttc
     8521 cgttgtaggc attagtcttt taatgggagt ccccactttg attcatgcga atgaattaaa
     8581 ctatggtcaa ctgtccatat ctcctatttt tcaaggaggc tcatatcaac tgaacaataa
     8641 gagtatagat atcagccctt tgttattaga taaattgtct ggagagagtc agacagtagt
     8701 aatgaaattt aaagcagata aaccaaactc tcttcaagct ttgtttggcc tatctaatag
     8761 taaagcaggc tttaaaaata attacttttc aattttcatg agagattctg gtgagatagg
     8821 tgtagaaata agagacgccc aaaagggaat aaattattta ttttctagac cagcttcatt
     8881 atggggaaag cataaaggac aggcagttga aaatacacta gtatttgtat ctgattctaa
     8941 agataaaaca tacacaatgt atgttaatgg aatagaagtg ttctctgaaa cagttgatac
     9001 atttttgcca atttcaaata taaatggtat agataaggca acactaggag ctgttaatcg
     9061 tgaaggcaag gaacattacc tcgcaaaagg aagtattgat gaaatcagtc tatttaacaa
     9121 agcaattagt gatcaggaag tttcaaatat tcccttgtca aatccatttc agttaatttt
     9181 ccaatcagga gattctactc aagctaacta ttttagaata ccgacactat atacattaag
     9241 tagtggaaga gttctatcaa gtattgatgc acgttatggt gggactcatg attctaaaag
     9301 taagattaat attgccactt cttatagtga tgataatggg aaaacgtgga gtgagccaat
     9361 ttttgctatg aagtttaatg actatgagga gcagttagtt tactggccac gagataataa
     9421 attaaagaat agtcaaatta gtggaagtgc ttcattcata gattcatcca ttgttgaaga
     9481 taaaaaatct gggaaaacga tattactagc tgatgttatg cctgcgggta ttggaaataa
     9541 taatgcaaat aaagccgact caggttttaa agaaataaat ggccattatt atttaaaact
     9601 aaagaagaat ggagataacg atttccgtta tacagttaga gaaaatggtg tcgtttatga
     9661 tgaaacaact aataaaccta caaattatac tataaatgat aagtatgaag ttttggaggg
     9721 aggaaagtct ttaacagtcg aacaatattc ggttgatttt gatagtggct ctttaagaga
     9781 aaggcataat ggaaaacagg ttcctatgaa tgttttctac aaagattcgt tatttaaagt
     9841 gactcctact aattatatag caatgacaac tagtcagaat agaggagaga gttgggaaca
     9901 atttaagttg ttgcctccgt tcttaggaga aaaacataat ggaacttact tgtgtcccgg
     9961 acaaggttta gcattaaaat caagtaacag attgattttt gcaacatata ctagtggaga
    10021 actaacctat ctcatttctg atgatagtgg tcaaacatgg aagaaatcct cagcttcaat
    10081 tccgtttgaa aatgcaacag cagaagcaca aatggttgaa ctgagagatg gtgtgattag
    10141 aacattcttt agaaccacta caggtaagat agcttatatg actagtagag attctggaga
    10201 aacatggtcg gaagtttcgt atattgatgg aatccaacaa acttcatatg gcacacaagt
    10261 atctgcaatt aaatactctc aattaattga tggaaaagaa gcagtcattt tgagtacacc
    10321 aaattctaga agtggccgta agggaggtca attagttgtc ggtttagtca ataaagaaga
    10381 tgatagtatt gattggaaat accactatga tattgatttg ccttcgtatg gttatgccta
    10441 ttctgcgatt acagaattgc caaatcatca cataggtgta ctgtttgaaa aatatgattc
    10501 gtggtcgaga aatgaattgc atttaagcaa tgtagttcag tatatagatt tggaaattaa
    10561 tgatttaaca aaataaagga gaaaaacatg gttaaatacg gtgttgttgg agcagggtat
    10621 tttggagctg aattggctcg ctacatgcaa aaaaatgatg gagcagagat tactcttctc
    10681 tatgatccag ataatgcaga ggcgattgca gaagaattgg gagcaaaagt agcaagttcc
    10741 ttagatgagt tggtttctag cgatgaagta gactgtgtta tcgtcgcaac tccaaataat
    10801 cttcataagg aaccggttat taaggctgca cagcatggta aaaatgtttt ctgtgaaaaa
    10861 ccaattgcgc tttcttatca agattgtcgc gagatggtag atgcgtgtaa agaaaacaat
    10921 gtaaccttta tggcaggaca tattatgaat ttctttaatg gtgttcatca tgcaaaagaa
    10981 ctcattaatc aaggagttat cggagacgtt ctatattgtc atacagctcg taatggttgg
    11041 gaagaacaac aaccgtcagt atcatggaaa aaaattcgtg aaaaatcagg tggtcacttg
    11101 tatcaccaca tccatgaatt ggattgcgtt caattcctta tggggggcat gcctgaaact
    11161 gtaaccatga caggtggaaa tgtggcccat gaaggtgaac atttcggtga tgaagatgat
    11221 atgatttttg tcaatatgga attttctaat aagcgttttg ccttgttaga atggggttca
    11281 gcttatcgtt ggggtgaaca ttatgtctta atccaaggaa gcaaaggtgc catccgctta
    11341 gacttattca actgtaaagg aactcttaag ctagatgggc aagaaagcta tttcttgatt
    11401 cacgaatcgc aagaagaaga tgatgatcgg actcgtatct atcatagtac agagatggat
    11461 ggagcaattg cttatggtaa accaggtaaa cgtactccat tatggctatc atctgtcatt
    11521 gataaagaaa tgcgctatct gcatgagatt atggaaggag ccccagtatc agaagaattt
    11581 gcaaaacttt tgacaggtga agctgcccta gaagcaattg ctactgcaga tgcttgtacc
    11641 cagtctatgt ttgaagatcg caaagtaaaa ttgtcagaaa ttgtaaaata aattttggta
    11701 ttctcctatt tataggtcga cttgctcctc tgaaagtact tttagaggag ctgtttgact
    11761 ttgctagttt ttgaaactga aatctattat actacaaact attgaaagcg ttttaatttt
    11821 aaggtataat aatctcatag aaataaagaa aaggaggaaa gaggatgcca cagattagca
    11881 aagaagcctt gattgagcaa atcaaagatg gaatcatcgt ttcttgtcag gctcttcctc
    11941 atgaaccgct ttatacagaa gcgggagggg tgattccctt gctggtcaaa gcggctgagc
    12001 aaggtggagc agtcggtatc cgagcaaaca gtgttcgcga tatcaaggaa attaaggaag
    12061 tcactaaact tccaatcatt gggattatca aacgtgatta tccacctcag gaacccttca
    12121 tcacggctac tatgaaagaa gttgatgaat tggcagaact ggacatcgag gtgattgctc
    12181 tggattgtac caagcgtgaa cgctacgatg gtttggaaat tcaagagttc attcgtcagg
    12241 ttaaggagaa atatcctaat cagcttttga tggctgatac tagtatcttc gaagaagggc
    12301 tagcagctgt agaagcagga attgactttg tcggaacaac cttatcaggc tacacatcct
    12361 acagtccaaa agtagacggt ccagattttg aattgattaa gaaactctgt gatgccggtg
    12421 tagatgtcat tgcagaagga aaaattcata caccagaaca agccaaacaa atccttgaat
    12481 atggagtgcg aggcatcgtt gttggtggcg ccattactag accaaaagag attacagaac
    12541 gcttcgttgc tagtcttaaa taagatgtga gagggagttt tatgtttaaa gttttacaaa
    12601 aagttggaaa agcttttatg ttacctatag ctatacttcc tgcagcaggt ctacttttgg
    12661 ggattggtgg tgcactttca aacccaacca cgatagcaac ttatccaata ctagacaata
    12721 gtatttttca atcaatattc caagtaatga gctctgcagg agaggttgta ttcagtaatt
    12781 tgtcactact tctctgtgtg ggattatgta ttggcttagc gaaacgagat aaaggaaccg
    12841 ctgcgttagc aggagtaact ggttacttag ttatgactgc aacgatcaaa gctttggtaa
    12901 aactttttat ggcagaagga tctgcaattg atactggagt tattggagca ttagttgtcg
    12961 gaatagttgc cgtatatttg cacaaccgat ataacaatat tcaattacct tccgctttag
    13021 gattctttgg aggttcacgc ttcgttccta ttgttacatc gttctcttct atcttgattg
    13081 gctttgtctt ctttgttatt tggccacctt tccaacaact tcttgtttct acaggtggat
    13141 atatttctca ggcgggtcca attggaactt ttctatatgg atttttaatg agactttctg
    13201 gagcagtagg cttacatcat ataatttacc ctatgttttg gtatactgaa cttggtggtg
    13261 ttgaaactgt tgcaggacaa acagtggttg gagctcaaaa aatatttttt gctcaattag
    13321 ccgatccggc ccattctgga ttatttacag aaggaacaag gttttttgca ggtcgtttct
    13381 caacaatgat gttcggttta ccggctgcct gtttagcgat gtaccatagt gttcctaaaa
    13441 atcgtcgtaa aaaatacgcg ggtttgtttt ttggagttgc tttaacatct tttattaccg
    13501 gtattacaga accaattgaa tttatgtttc tattcgtcag tccggttcta tatgttgttc
    13561 acgcattcct tgatggtgtt agcttcttta ttgcagacgt cttaaatatt tcaataggaa
    13621 acacattttc aggaggtgta atcgatttca ctttatttgg aattttgcag gggaacgcta
    13681 agacgaattg ggttcttcag attccaattg gacttatttg gagtgttttg tattatatta
    13741 tttttagatg gttcattact caattcaacg ttctaacgcc aggacgagga gaagaagtag
    13801 attctaaaga aatttctgaa tccgcagatt caacttcaaa tactgcagat tatttaaaac
    13861 aggatagcct acaaattatc agagccttgg gtggatcaaa taatatagaa gatgtagatg
    13921 cttgtgtgac acgtttacgt gtagctgtaa aagaagttaa tcaagttgat aaagcacttt
    13981 taaaacaaat tggtgcagtt gatgtcttag aagtgaaggg tggcattcaa gcaatatatg
    14041 gagcaaaagc aatcttatat aaaaatagta ttaatgaaat tttaggtgta gatgattaag
    14101 tacttactga cttaataaaa aacagaggag agtgatggat gagtaggatg aaatgaaatc
    14161 gcatacaaga aataaagaac tcattatcca agttggatac gcttattaca taggagaata
    14221 caaatgaaat ttagaaaatt agcttgtaca gtacttgcgg gtgctgcggt tcttggtctt
    14281 gctgcttgtg gcaattctgg cggaagtaaa gatgctgcca aatcaggtgg tgacggtgcc
    14341 aaaacagaaa tcacttggtg ggcattccca gtatttaccc aagaaaaaac tggtgacggt
    14401 gttggaactt atgaaaaatc aatcatcgaa gcgtttgaaa aagcaaaccc agatataaaa
    14461 gtgaaattgg aaaccatcga cttcaagtca ggtcctgaaa aaatcacaac agccatcgaa
    14521 gcaggaacag ctccagacgt actctttgat gcaccaggac gtatcatcca atacggtaaa
    14581 aacggtaaat tggctgagtt gaacgacctc ttcacagatg aatttgttaa agatgtcaac
    14641 aatgaaaaca tcgtacaagc aagtaaagct ggagacaagg cttatatgta tccgattagt
    14701 tctgccccat tctacatggc aatgaacaag aaaatgttag aagatgctgg agtagcaaac
    14761 cttgtaaaag aaggttggac aactgatgat tttgaaaaag tattgaaagc acttaaagac
    14821 aagggttaca caccaggttc attgttcagt tctggtcaag ggggagacca aggaacacgt
    14881 gcctttatct ctaaccttta tagcggttct gtaacagatg aaaaagttag caaatataca
    14941 actgatgatc ctaaattcgt caaaggtctt gaaaaagcaa ctagctggat taaagacaat
    15001 ttgatcaata atggttcaca atttgacggt ggggcagata tccaaaactt tgccaacggt
    15061 caaacatctt acacaatcct ttgggcacca gctcaaaatg gtatccaagc taaactttta
    15121 gaagcaagta aggtagaagt ggtagaagta ccattcccat cagacgaagg taagccagct
    15181 cttgaatacc ttgtaaacgg atttgcagta ttcaacaata aagacgacaa gaaagtcgct
    15241 gcatctaaga aattcatcca gtttatcgca gatgacaaag agtggggacc taaagacgta
    15301 gttcgtacag gtgctttccc agtccgtact tcatttggaa aactttatga agacaaacgc
    15361 atggaaacaa tcagcggctg gactcaatac tactcaccat actacaacac tattgatggt
    15421 tttgctgaaa tgagaacact ttggttccca atgttgcaat ctgtatcaaa tggtgacgaa
    15481 aaaccagcgg atgctttgaa agccttcact gaaaaagcaa acgaaacaat caaaaaagct
    15541 atgaaacaat agtccttagt tattctataa aaagtagttt tttaaagaac ctaagagtgt
    15601 ataccccctt ttccctctac acagatagtg taagaaaagg gggcttttgt ttaaaatgta
    15661 agaaactgtc acgaaattaa aatgaagttc ttacataagc gaatcataaa aaatttcatt
    15721 ttgattttaa aacagttcaa gaaagtcaaa aaattattct atttgaaaga gaggtgccga
    15781 ctgtgaaagt caataaaatc cgtatgcggg aaacagtgat ttcctacgct ttcctagcac
    15841 cagtattatt cttctttgtc atctttgtgt tggctccgat ggtgatgggc ttcattacaa
    15901 gtttctttaa ctactcaatg actaaatttg agtttgtagg cttggataac tatatccgta
    15961 tgtttaaaga tcctgtcttt acaaaatctc tgattaacac agttattttg gttattggat
    16021 ctgtaccagt tgttgttcta ttctcactct ttgtagcatc tcagacctat catcaaaatg
    16081 tcattgccag atccttctac cgtttcgtct tcttccttcc tgttgtaacg ggtagtgttg
    16141 ccgtgacagt tgtttggaaa tggatttatg acccgctatc agggattcta aactttgtcc
    16201 ttaagtcaag ccacatcatc agccaaaaca tttcttggtt gggagataaa aactgggcat
    16261 tgatggcgat tatgattatt ctcttgacca cttcagttgg tcagcccatc atcctttata
    16321 tcgctgccat ggggaatatt gacaattcac tggttgaagc ggcgcgtgtt gatggtgcaa
    16381 ctgagtttca agttttttgg aagattaaat ggccaagcct tcttccaaca actctttata
    16441 ttgcaatcat cacaacaatt aactcattcc agtgtttcgc cttgattcag cttttgacat
    16501 ctggtggtcc aaactactca acaagtacct tgatgtacta cctttacgaa aaagccttcc
    16561 aattgacaga atacggctat gccaacacaa ttggtgtctt cttggcagtc atgattgcta
    16621 tcgtaagctt tgttcaattt aaagtacttg gaaacgacgt agaatactaa agaaaggaga
    16681 cagctatgca atctacagaa aaaaaaccat taacagcctt tactgttatt tcaacaatca
    16741 ttttgctctt gttgactgtg ctgttcatct ttccattcta ctggattttg acaggggcat
    16801 tcaaatcaca acctgataca attgttattc ctcctcagtg gttccctaaa atgccaacca
    16861 tggaaaactt ccaacaactc atggtgcaga accctgcctt gcaatggatg tggaactcag
    16921 tatttatctc attggtaacc atgttcttag tttgtgcaac ctcatctcta gcaggttatg
    16981 tattggctaa aaaacgtttc tatggtcaac gcattctatt tgctatcttt atcgctgcta
    17041 tggcgcttcc aaaacaagtt gtccttgtac cattggtacg tatcgtcaac ttcatgggaa
    17101 tccacgatac tctctgggca gttatcttgc ctttggttgg atggccattc ggtgtcttcc
    17161 tcatgaaaca atttagtgaa aatattccta cagagttgct tgaatcagct aaaatcgacg
    17221 gttgtggtga gattcgtacc ttctggagtg tagccttccc gattgtgaaa ccagggtttg
    17281 cagcccttgc aatctttacc ttcatcaata cttggaatga ctacttcatg caattggtaa
    17341 tgttgacttc acgtaacaat ttgaccatct cacttggggt tgcgaccatg caggctgaaa
    17401 tggcaaccaa ctatggtttg attatggcag gagctgccct tgctgctgtt ccaatcgtca
    17461 cagtcttcct tgtcttccaa aaatccttca cacagggtat tactatggga gcggtcaaag
    17521 gataatactc tgcgaaaatc gaatgcaaac tacgtcagct tcaccttgcc atacttaagt
    17581 attgcctgcg gttagcttcc tagtttgttc ttcaattttc attgagtata ggaaaatcaa
    17641 tctatcaaga tacagaagta tattttatag atttagagaa tatagaagtt ataagtgtct
    17701 acaaaatgga gggtatgcag ttactttatg aagttttgtc agacacttat caacttaaga
    17761 atgattttag ttaattatca gaaacgaagg aaagagtatg atttttgacg atttgaaaaa
    17821 catcaccttt tacaaaggga ttcatcccaa tttagacaag gctatcgact atctctacca
    17881 acatcgtaga gattcattcg aattaggaaa gtatgagatt gatggagata aagtctttct
    17941 agttgttcag gaaaatgtcc tcaatcaagt tgagaataat caatttgaac accataagaa
    18001 ctatgcagat ttgcatttgc tgatagaagg gcatgaatat tcgagctacg gttcacgtat
    18061 caaagaagag gcagtagcat tcgacgaagc gagtgacatt ggctttgttc attgttatga
    18121 acactaccca ctcttattgg gttatcacaa ttttgcgatt ttcttcccag gtgagccaca
    18181 tcagccaaat ggttatgcag gcatggaaga aaaggttcga aaatatctct ttaaaatctt
    18241 gattgattaa aaataggatg aattgttttt ttgtaaagct ttgataatac tctaccatga
    18301 aattgatctt tgtgaggtag agaaatgaga ataaaatatt taaaaattgg tatcttctaa
    18361 gtatgctgca agagctagtt tcttagatgg acaggggatt acagttgatg agatgtcctg
    18421 gataattagg ggcattgtga atggattgat tggtagatac ataaaattag gtacttatgc
    18481 agctaagtat ggtattagta tggcgcgctc gatcttaagt agggcagctg caactgcggc
    18541 agcaagagta ggattattga ctaagatttt tggatggatt ttacgaatag ctgtgctcgc
    18601 agctgatgta tatggtaatt ttgccaacaa tattgctgta gcttgggatg cacatgataa
    18661 aatccctaac aatggtcgta taaactttta aaatgcgaga atgaaagcac tttgtatttt
    18721 tttattgaat atgttagctt ggacagtgct tgcaatgata attcgtggag ggctagatgg
    18781 atttaatgag catacttgga gtactatttt aattgcttcg ctgtccggga tatatataga
    18841 ttatatgtcc atagataaaa gtagaaaaaa gtccaaaaga aaaaagaaaa aatagatttg
    18901 ttcatggtag ggacttatga aagttttact gacaaaaaag aaaacagttt acaaagaaaa
    18961 atgatggagg agcaaacatg gcacaaaaag gagtaagcct tatcaaggca gcatttgata
    19021 cagataactt tctcatgcgt tttagtgaga aagtcttgga catcgtgaca gccaatcttc
    19081 tttttgtcgt ctcttgtttg cccatcgtga cgattggagt ggctaaaatc agcctctacg
    19141 agaccatgtt cgaagttaag aagagcagac gggtgcctgt ttttaaaatc tatctaagat
    19201 ctttcaagca aaatctgaaa ctaggtcttc agctgggttt aatggagtta ggaattgtgt
    19261 ttcttaccct ttcagatctc tatcttttct ggggtcaaac agctctgccc ttccaattgc
    19321 tgaaagccat ttgtttaggt attctgattt ttcttactat cgtgatgctg gctagttacc
    19381 ctatcgcggc acgttatgac ctatcttgga aagaaattct tcaaaaagga ttgatgttgg
    19441 ctagttttaa ctttccttgg ttcttcctca tgttagccat tcttgtcctc attgtgatgg
    19501 ttctttatct gtccgccttc agtctactct taggtggctc agtcttccta ctttttgggt
    19561 ttggactatt ggtctttatc cagactggat tgatggagaa aattttcgca aaataccaat
    19621 aggagcttta tttctgaaac tactttcaaa ggctccaaac gctattctat aagcgagaaa
    19681 ctaaaatcta agtgtctata agatattgaa agccttttcg gtaaagtgta tactaaagaa
    19741 gtaaagaaaa atctgcttta gcagaaaata aaaataatag gagaaaatct atgtcagatt
    19801 tgaaaaaata cgaaggtgtc attccagcct tctacgcatg ttatgatgat caaggagaag
    19861 taagcccaga acgtacgcgt gccttggttc aatacttcat tgataaaggt gttcaaggtc
    19921 tttatgtcaa tggttcttct ggtgaatgta tctaccaaag cgttgaagat cgcaagttga
    19981 ttttggaaga agtcatggcg gtagccaaag gtaaattgac cattattgcc catgttgctt
    20041 gcaataatac taaagatagt atggaacttg ctcgccatgc tgaaagcttg ggagtagatg
    20101 ctattgcaac gattccacca atttatttcc gcttgccaga atactcagtt gccaaatact
    20161 ggaacgatat cagttctgca gctccaaaca cagactacgt gatttacaac attcctcaat
    20221 tggcaggggt tgctttgact ccaagccttt acacagaaat gttgaaaaat cctcgtgtta
    20281 tcggtgtgaa gaactcttct atgccagttc aagatatcca aacctttgtc agccttggtg
    20341 gagaagacca tatcgtcttt aatggtcctg atgagcagtt cctaggagga cgcctcatgg
    20401 gggctagggc tggtatcggt ggtacttatg gtgctatgcc agaactcttc ttgaaactca
    20461 atcagttgat tgcggataag gacctagaaa cagcgcgtga attgcagtat gctatcaacg
    20521 caatcattgg taaactcact tctgctcatg gaaatatgta cggtgtcatc aaagaagtct
    20581 tgaaaatcaa tgaaggcttg aatattggat ctgttcgttc accattgaca ccagtgactg
    20641 aagaagatcg tccagttgta gaagcggctg ctgccttgat tcgtgaaacc aaggagcgct
    20701 tcctctaatc taaaaggagg tatttatgac atattacgtt gcaattgata tcggtggaac
    20761 caacatcaag tatggtttgg ttgatcaaga ggggcaactt cttgaatcgc atgaaatgcc
    20821 aactgaggcg cataagggtg gacctcatat cttacaaaag accaaagata tcgtagctag
    20881 ttatttagaa aaaggcccag tagcaggtgt tgccatatct tctgctggga tggtggatcc
    20941 ggataagggt gagattttct atgctgggcc gcaaatccct aactacgcag gcacccagtt
    21001 caaaaaggaa atcgaagaaa gctttactat tccttgtgag attgaaaatg atgtcaactg
    21061 tgcaggtctt gctgaggcag tatctggttc aggcaaggga gcaagtgtga cactttgctt
    21121 gaccattgga accggtatcg gtggttgctt gattatggat aggaaagtct tccatggttt
    21181 tagcaattca gcctgtgaag tcgggtatat gcatatgcag gatggagctt ttcaagactt
    21241 ggcttctaca acagctttag tgaaatatgt agctgaagcc catggagaag atgttgatca
    21301 gtggaatggc cgtagaattt tcaaagaagc cactgaagga aacaaaatct gcatggaagg
    21361 tattgaccgt atggttgact atctaggaaa aggtctggca aatatttgct acgttgccaa
    21421 tccagaagtg gttattcttg gtggtggtat catggggcaa gaggctatcc tcaaacctaa
    21481 gatccgtaca gccttgaaag aggctttggt accaagttta gcagaaaaaa cacgattaga
    21541 atttgcccat caccaaaata cagcagggat gttgggtgca tattatcatt ttaagacaaa
    21601 acaatcctag tttggctcag ccaaactagg attttcttac acgtttttgt ctacgatagc
    21661 cgttgagttt tttattttcc cagtagctat taaagatttt ttccttgctt tcgcgattga
    21721 tttccaaaaa gtaggcataa atcaaatcga taaagaagag cataggaagt tgagcggata
    21781 ttcgttggat ataggagggt tggctgtggg tggctacaag aacagtctct gtataggtct
    21841 ggctatcttt attgggaaca cttgtaaaga gtacagtctt tgcccccatc tccttagcat
    21901 ctaatagact atctaaaata gaaggagttg agcctgaaag tgagaagccc agtactagac
    21961 aattttcatc catgatgctg gttgtccagg caaagccgtc ttggtctgtc aaagcttcgc
    22021 agaccacacc tagtcgcata aaacgtaatt tcatttcacg ggcgacgagg ccagaactcc
    22081 ctgttccaaa gaagtagata cgctcagcat cttcgattag ctgggcaatt cgttctagtt
    22141 ggatttcgtc aatcaagtct tgtgtttgtt ccctcatatt gctataactt ctgaggactc
    22201 gtttggtcag tggactgtgc ttggagactt ggttggcttg attttctgcc tgatgttggt
    22261 attggaaaat aaattctcgg tagccagtaa agccacactt tttagcaaag cgggtcaaag
    22321 cagcttgaga aatatgtaat ttttgggtga cttgttgaga agataaatca tctgtaatcg
    22381 tttcagcttg caaaaaatag cgagcgattt cttgttctag gtctgtcatt tcttcaaaat
    22441 gtgaatcaat gatagttgcg atatctggtt tgtccatagg gaaagctcct ttacatgagt
    22501 catactggaa gactagatca gagaatagtc acacttcatt ataacacata atataaggat
    22561 agataaataa aaacgcatct ctgttttaaa aacgaaaaaa tcgaaaaagc ttctctcttt
    22621 tccataattt tctactcaaa ttgtggtaca attaagagta agattttaag ttagaaatga
    22681 gactgatttg tatgagaaaa tttaacagcc attcgattcc gattcggctt aatttattgt
    22741 tttcaatcgt cattttactc tttatgacca ttattggtcg tttgttgtat atgcaggttt
    22801 tgaacaagga tttttacgaa aaaaagctag cttcagctag tcagaccaag attacaagca
    22861 gttcagcccg tggggaaatt tatgatgcta gtggaaaacc tttggtagaa aatacgttaa
    22921 agcaggttgt ttcctttacg cgtagcaata aaatgacggc tacagactta aaagaaacag
    22981 ctaaaaagtt actgacttat gtgagcatca gttctccaaa tttgacagaa cgccagctgg
    23041 cggattacta tttggctgat cctgaaatct ataaaaaaat agtggaagct ctcccaagtg
    23101 agaaacgctt ggattcagat ggcaatcgtc tatccgaatc agaactgtat aacaatgcgg
    23161 tcgatagtgt acaaacgagt caactaaact atacagagga tgaaaagaaa gaaatctatc
    23221 tttttagtca gttaaatgct gttggaaact ttgcgacagg aaccattgcg acagatcctc
    23281 taaatgattc tcaggtggct gttattgcct ctatttcaaa ggagatgcct ggcattagta
    23341 tttctacttc ttgggataga aaggttttgg aaacttccct ttcttctata gttgggagtg
    23401 tatccagtga aaaagctggt ctcccagcgg aagaagcaga agcctatctt aaaaaaggct
    23461 attctctaaa tgaccgtgta ggaacctcct atttggaaaa gcaatatgaa gagaccttac
    23521 aaggaaaacg ctcggtaaaa gaaatccatc tggataaata tggcaatatg gaaagcgtgg
    23581 atacaattga ggaaggtagt aagggaaaca atatcaaact gaccattgat ttggccttcc
    23641 aagatagcgt ggatgcttta ctgaaaagtt atttcaattc tgagctagaa aatggtggag
    23701 ccaagtattc tgaaggtgtc tatgcagtcg cccttaaccc aaaaacaggt gcggttttgt
    23761 ctatgtcagg gattaaacat gacttgaaaa cgggagagtt gacgcctgat tccttgggaa
    23821 cggtaaccaa tgtctttgtt ccaggttcgg ttgtcaaggc ggcgaccatc agctcaggtt
    23881 gggaaaatgg agtcttgtca ggaaaccaga ccttgacaga ccagtccatt gtcttccaag
    23941 gttcagctcc catcaattct tggtatactc aggcttacgg ttcattccct atcacagcgg
    24001 tccaagctct ggagtattca tcaaatacct atatggtcca aacagcctta ggtcttatgg
    24061 ggcaaaccta tcaacccaat atgtttgtcg gcaccagcaa tctagagtct gctatggaga
    24121 aactgcgttc aacctttggc gaatatggct tgggtactgc gacaggaatt gacctaccag
    24181 atgaatctac tggatttgtt cccaaagagt atagctttgc taattacatt actaatgcct
    24241 ttgggcagtt tgataactat acgccgatgc agttggctca gtatgtagca actattgcaa
    24301 ataatggtgt tcgtgtggct cctcgtattg ttgaaggcat ttatggtaat aatgataagg
    24361 gaggactggg tgacttgatt cagcaactgc aaccgacaga gatgaataag gtcaatatat
    24421 ccgactccga tatgagcatc ttgcaccaag gtttttatca ggttgcccat ggtactagtg
    24481 gattgacaac tggacgtgcc ttttcaaatg gtgccttggt atccattagc ggaaaaacag
    24541 gtacagccga aagctatgtg gcagatggtc agcaagcaac caataccaat gcggtggcct
    24601 atgccccatc tgataatccc caaatcgctg tcgcagtggt ctttcctcat aataccaatc
    24661 taacaaatgg tgtaggacct tccattgcgc gtgacattat caatctgtat caaaaatacc
    24721 atccaatgaa ctagaaagga aattatgctt tatccaacac ctattgccaa gttgattgac
    24781 agttattcta agttaccagg tatcgggatt aagacggcta cgcgtctggc cttttatacg
    24841 attgggatgt ctgctgatga tgtcaatgaa tttgcaaaaa atctcctttc tgctaagaga
    24901 gaattgacat attgttctat ttgtggacgt ttgacagacg acgatccttg ttctatctgt
    24961 actgatccga ctcgtgacca gacaacaatt ttagttcttg aggatagtag agatgtggca
    25021 gccatggaaa atatccaaga ataccatgga ctctatcatg tccttcatgg cctcatttct
    25081 cctatgaatg gtatcagtcc ggacgatatc aatctcaaga gccttatgac tcgtcttatg
    25141 gatagtgagg tttcagaagt gattgtggcg actaatgcta cagcggatgg tgaagcgact
    25201 tccatgtatc tttcacgttt gctcaagccg gctggtatca aggttacgcg tctagcacga
    25261 ggtctcgctg tgggagcgga cattgagtat gcggacgaag tgacactctt acgagccatt
    25321 gaaaatcgga cagagttgta agtgtaggca aatttacgaa ctccattcat ttataaaaaa
    25381 tcaaagaggc tgaaaatcgt tcctatcggc ctctttttgt atagtgtgat gagtaggctc
    25441 aggttcaagt tttaaaaaac caagcaaata tgatatacta aagagcgagt attctagtag
    25501 aattaggaca aataatatga aacaaacgat tattctttta tatggtggac ggagtgcgga
    25561 acgcgaagtc tctgtccttt cagctgagag tgtcatgcgt gcggtcgatt acgaccgttt
    25621 cacagtcaag actttcttta tcagtcagtc aggtgacttt atcaaaacac aggaatttag
    25681 tcatgctccg gggcaagaag accgtctcat gaccaatgaa accattgatt gggataagaa
    25741 agttgcacca agtgctatct acgaagaagg tgcagtggtc tttccagtcc ttcacgggcc
    25801 aatgggagaa gatggctctg ttcaaggatt cttggaagtt ttgaaaatgc cttacgttgg
    25861 ttgcaacatt ttgtcatcaa gtcttgccat ggataaaatc acgactaagc gtgttctgga
    25921 atctgctggt attgcccaag ttccttatgt ggctatcgtt gaaggcgatg atgtgactgc
    25981 taaaatcgct gaagtggaag aaaaattagc ttatccagtc ttcactaagc cgtcaaacat
    26041 ggggtctagt gtcggtattt ctaagtctga aaaccaagaa gaactccgtc aagccttaaa
    26101 acttgccttc cgatatgaca gccgtgtctt ggttgagcaa ggagtgaatg cccgtgaaat
    26161 tgaggttggc ctcttgggta actacgatgt caagagcacg ctacctggag aagttgtcaa
    26221 ggacgttgcc ttttatgact acgatgccaa gtatattgat aacaagatta ctatggatat
    26281 tcctgccaaa atcagtgatg atgtggtggc tgtcatgcgt caaaatgcag aaacagcctt
    26341 ccgtgccatt ggtggccttg gtctatctcg ttgcgatttc ttctatacag ataagggaga
    26401 gatttttctc aacgagctca ataccatgcc aggttttacc cagtggtcta tgtacccact
    26461 actttgggac aatatgggga tcagctaccc agaactaatc gaacgtttgg ttgaccttgc
    26521 caaggaaagc tttgacaagc gcgaagcgca tttgatataa aatgaaagag agggtagaag
    26581 ccagaaccat cactgcacgg tgactagagt tctcggactt cagccctttt taaaggagta
    26641 gaaatgaaat taacaatcca tgaaattgcc caagttgttg gagccaaaaa tgatatcagt
    26701 atctttgagg acacccagtt agaaaaagct gagtttgata gtcgtttgat tggaactgga
    26761 gatttatttg tgccacttaa aggtgcgcgt gatggccatg actttattga aacagccttt
    26821 gaaaatggtg cagcagtaac cttgtctgag aaagaggtct caaatcatcc ttacatttta
    26881 gtagatgatg ttttgacagc ctttcaatcc ctagcatcct actatcttga aaaaacgact
    26941 gttgatgtct ttgctgttac aggttcaaat ggcaagacaa cgactaagga tatgttggcg
    27001 catttactgt caacaagata caagacctac aaaacacaag gcaattacaa taatgagatt
    27061 ggccttcctt acacagttct ccacatgcct gaaggaacag aaaagttggt cttggagatg
    27121 gggcaggacc acttgggaga tattcatctc ttgtctgaat tggctcgtcc aaaaacagtc
    27181 atcgtgacct tggttggaga agctcatttg gcctttttca aagatcgttc tgagattgct
    27241 aaaggaaaaa tgcaaattgc agacggaatg gcttcaggtt ccttgttttt agcgccggct
    27301 gaccctatcg tagaggacta tttgccaact gataaaaagg tggttcgttt tggtcaagga
    27361 gcagagctgg aaattactga cttggttgag cgcaaagata gtctgacctt caaggccaat
    27421 ttcttagagc aagtccttga tttgccagta actggcaagt acaatgcgac aaatgctatg
    27481 attgcatcct atgttgcctt gcaagaagga gtttcagagg agcaaattcg tttggccttc
    27541 caacatcttg aattgacgcg taaccgtacc gagtggaaga aagcagtcaa tggagcagat
    27601 atcctgtcag atgtttacaa tgccaatcca actgctatga aactgatttt agagactttc
    27661 tctgccattc cagccaatga aggtggcaag aaaattgcag ttttggcgga tatgaaggag
    27721 cttggtgacc agtctgttca acttcataat cagatgattt tgagcctctc cccagatgtg
    27781 cttgatatcg ttattttcta tggagaagat attgctcagt tggctcaatt ggccagtcaa
    27841 atgtttccaa tcggccacgt ttactacttc aagaaaacag aagaccagga tcaatttgaa
    27901 gacctagtca agcaggttaa ggaaagcctt ggagcctatg accaaatctt gctaaaaggt
    27961 tctaactcta tgaatctagc caaattggta gaaagtttag aaaatgaagc caagtgattt
    28021 tgttaagtat ctgcaaagaa tgattgccct tacagatact ggcttaacct ttacaaaaga
    28081 tccttttgac cgtgagcgct acgaggactt gcgaagtctg ttatctgaaa tgttgaatca
    28141 gggatcagac ctggatgtag aagaagtagc agaagtcttg aaaccaactt cagcttatgc
    28201 gactccctta atggacgtcc gtgcttggat tgttgaggat gagaagattt gtctggttag
    28261 gggacaagga gaggatagtt gggctttgcc aggtggcttt ggtgaagtcg gctattctcc
    28321 aactgaaaat attctcaagg aaattgaaga agaaaccggt tttaaagcca aagttgaaag
    28381 actgctagct gtttttgata ccaatcgttt ccaactacag agcaaacaat atgcaaagtt
    28441 tgtttttgaa tgtaagcttc tcgatggaca attccaagaa aatcaagaaa tcgctgacct
    28501 tcaatttttt gcaattgacc aactgccgaa tttatctgaa aaacgcatta ccaaggagca
    28561 aatcgagatt ctttggcagg tttatcaagg tcagagggag caatatcttg actaagaaga
    28621 tgattatcgt atttctaaat ccatttttga caactagcat ggtataataa tatgcaggaa
    28681 aattttgaat tatgaggaag actagatgaa tttatgggat attttcttta cgactcaggc
    28741 aaccgagccg cccaaatttg accttttttg gtatgttagc ctatttacgc tcttagcctt
    28801 aaccttttat acagcccatc gctatcgtga aaagaaggtt taccaacgat ttttccaaat
    28861 cttgcagact gttcagttaa tccttcttta tggttggtac tgggttaatc atatgccact
    28921 gtcagaaagc ctaccctttt accattgccg tatggctatg tttgtggtac tcttgcttcc
    28981 tggtcagtcc aaatataaac aatactttgc attattggga acatttggga cattagcagc
    29041 ctttgtttat ccagtgccag atgcttaccc ttttccacat gtcaccattc tatcctttat
    29101 ctttggtcat ttagcactct tggggaactc tctagtttat ctattgagac agtataatgc
    29161 gcgattgctg gatgtgaagg gaatttttct catgaccttt gccctaaatg ccttgatttt
    29221 tgtggtcaat ttggtgacag gtggcgatta cggatttttg acaaaaccgc cattggttgg
    29281 ggatcacggt ctagtagcta attatttact tgtttcaatt gtgctggtag ctactatcag
    29341 tttgactaag aaaatcttag aattcttttt agctcaagaa gcagaaaaaa tgattgcaaa
    29401 ggaagcttaa cacagagctt tcttttttgc tcttagagag tttttacaag cagcttataa
    29461 aataagaatt tctgaataga caaactcaaa aaatggctgg gaaatttagg aaaaaagcaa
    29521 gcacgattaa attttttgtg ttataatatt ttgtgaatag ctatgcctat gtttagctat
    29581 ggaataatac gaagtgcgaa acttggaaga tagagaggaa gcgatgtaat ggctagagaa
    29641 ggctttttta caggtctaga tattggaaca agctctgtca aggtgcttgt ggccgagcag
    29701 agaaatggtg aattaaatgt aattggcgtg agtaatgcca aaagtaaagg tgtaaaggat
    29761 ggaattattg ttgatattga tgcagcagca actgctatca agtcagccat ttcccaagcg
    29821 gaagaaaagg caggcatttc gattaaatca gtgaatgtcg gcttgcctgg taatcttttg
    29881 caggtagaac caactcaggg gatgattcca gtaacatctg atactaagga aattacggat
    29941 caagatgttg aaaatgttgt caaatcagct ttgacaaaga gtatgacacc tgaccgtgaa
    30001 gtcattacct ttattcctga agaatttatt gtggatggtt tccaagggat tcgtgaccca
    30061 cgtggtatga tgggggttcg ccttgaaatg cgtggtttgc tttatacagg acctcgtact
    30121 atcttgcaca atttgcgtaa gacggttgag cgtgcaggtg ttcaggttga aaatgttatc
    30181 atttcaccac tagcaatggt tcagtctgtt ttgaacgaag gggaacgtga atttggtgct
    30241 acagtgattg atatgggggc aggtcaaacg actgtcgcta caatccgtaa tcaagaactc
    30301 cagttcacac atattctcca agaaggtgga gattatgtaa ctaaagatat ctccaaggtt
    30361 ttgaaaacct ctcgcaaatt agcggaaggc ttgaaactga attacgggga agcctatccg
    30421 cctcttgcaa gcaaagaaac cttccaagta gaggttattg gagaagtgga agcagtcgaa
    30481 gtgacggaag cctacttgtc agaaattatt tctgcacgaa tcaagcacat ccttgaacaa
    30541 atcaagcaag aattagatag aaggcgtcta ttggacctcc ctggtggtat tgtcttaatc
    30601 ggtgggaatg ccattttacc aggtatggtt gagcttgctc aggaagtctt tggcgtccgt
    30661 gtcaagcttt atgttccaaa tcaagttggt atccgtaatc cagcctttgc gcatgtgatt
    30721 agtttatcag aatttgcggg tcaattaaca gaagttaatc ttttggctca gggagcgata
    30781 aaaggtgaga atgacttaag tcatcagcca attagttttg gtgggatgct gcaaaaaaca
    30841 gctcagtttg tacaatcaac gcctgttcaa ccagcacctg ctccagaagt agagccggtg
    30901 gcgcctacag aaccaatggc ggatttccaa caagcttcac aaaataaacc gaaattagca
    30961 gatcgtttcc gtggcttgat cggaagcatg tttgacgaat aaagaggaaa aataaattat
    31021 gacattttca tttgatacag ctgctgctca aggggcagtg attaaagtaa ttggtgtcgg
    31081 tggaggtggt ggcaatgcca tcaaccgtat ggtcgacgaa ggtgttacag gcgtagaatt
    31141 tatcgcagca aacacagatg tacaagcatt gagtagtaca aaagctgaga ctgttattca
    31201 gttgggacct aaattgactc gtggtttggg tgcaggaggt caacctgagg ttggtcgtaa
    31261 agccgctgaa gaaagcgaag aaacactgac ggaagctatt agtggtgccg atatggtctt
    31321 catcactgct ggtatgggag gaggctctgg aactggagct gctcctgtta ttgctcgtat
    31381 cgccaaagat ttaggtgcgc ttacagttgg tgttgtaaca cgtccctttg gttttgaagg
    31441 aagtaagcgt ggacaatttg ctgtagaagg aatcaatcaa cttcgtgagc atgtagacac
    31501 tctattgatt atctcaaaca acaatttgct tgaaattgtt gataagaaaa caccgctttt
    31561 ggaggctctt agcgaagcgg ataacgttct tcgtcaaggt gttcaaggga ttaccgattt
    31621 gattaccaat ccaggattga ttaaccttga ctttgccgat gtgaaaacgg taatggcaaa
    31681 caaagggaat gctcttatgg gtattggtat cggtagtgga gaagaacgtg tggtagaagc
    31741 ggcacgtaag gcaatctatt caccacttct tgaaacaact attgacggtg ctgaggatgt
    31801 tatcgtcaac gttactggtg gtcttgactt aaccttgatt gaggcagaag aggcttcaca
    31861 aattgtgaac caggcagcag gtcaaggagt gaacatctgg ctcggtactt caattgatga
    31921 aagtatgcgt gatgaaattc gtgtaacagt tgttgcaacg ggtgttcgtc aagaccgcgt
    31981 agaaaaggtt gtggctccac aagctagatc tgctactaac taccgtgaga cagtgaaacc
    32041 agctcattca catggctttg atcgtcattt tgatatggca gaaacagttg aattgccaaa
    32101 acaaaatcca cgtcgtttgg aaccaactca ggcatctgct tttggtgatt gggatcttcg
    32161 ccgtgaatcg attgttcgta caacagattc agtcgtttct ccagtcgagc gctttgaagc
    32221 cccaatttca caagatgaag atgaattgga tacacctcca tttttcaaaa atcgttaagt
    32281 aaatgaatgt aaaagaaaat acagaacttg tttttcgaga agttgcagag gctagtctga
    32341 gtgctcatcg agagagtggt tcggtctctg tcattgcagt taccaagtat gtagatgtac
    32401 cgacagcgga agccttgctt ccgctaggtg tccatcatat cggtgaaaat cgtgtagata
    32461 agtttctgga aaaatatgaa gctttaaaag atcgagatgt gacttggcat ttgattggta
    32521 ccttgcaaag acgtaaggtg aaagatgtca ttcaatacgt tgattatttc catgcattgg
    32581 actcagtaaa gctagcaggg gaaattcaaa aaagaagtga ccgagtcatc aagtgtttcc
    32641 ttcaagtaaa tatttctaaa gaagaaagca aacacggttt ttcgagagag gaactgctgg
    32701 aaatcttgcc agagttagcc agactagata agattgaata tgttggttta atgacgatgg
    32761 caccttttga ggctagcagt gagcagttga aagagatttt caaggcggcc caagatttac
    32821 aaagagaaat tcaagagaaa caaattccaa atatgcctat gaccgagtta agtatgggaa
    32881 tgagtcgtga ttataaagaa gcgattcaat tcggttccac ttttgttcgt ataggtacat
    32941 cattttttaa gtaggagaga accatgtctt taaaagatag attcgataga tttatagatt
    33001 attttacgga ggatgaggat tcaagtctcc cttatgaaaa aagagatgag cctgtgttta
    33061 cttcagtaaa ttcttcacag gaaccggctc tcccaatgaa tcaaccttca cagtcggctg
    33121 ggacaaaaga gaacaatatc accagacttc atgcaagaca acaggaattg gcaaatcaga
    33181 gtcagcgtgc aacggataag gtcattatag atgttcgtta tcctagaaaa tatgaggatg
    33241 caacagaaat tgttgattta ttggcaggaa acgaaagtat cttgattgat tttcagtata
    33301 tgacagaggt gcaggctcgt cgttgtttgg actatttgga tggagcttgt catgttttag
    33361 ctggaaattt gaaaaaggta gcttctacca tgtatttgtt gacaccagtg aacgttattg
    33421 taaatgttga agatatccgt ttaccagatg aagatcaaca gggtgagttc ggttttgata
    33481 tgaagcgaaa tagagtacga taatgatttt tttaattcgt atgatttata atgcagtgga
    33541 tatttactcc ctaattttgg tagccttcgc tgtcatgtct tggtttccag gtgcctacga
    33601 atccagttta ggtcgttgga ttgtagcgtt ggtaaaacca gtgcttgctc ccttgcaacg
    33661 cctgccttta cagatagcgg gtcttgattt atctgtttgg gtcgcgattg ttttggttcg
    33721 atttttagga gaaaacctag tgcgttttct ggcgatgata ggatgaataa agggatttat
    33781 cagcatttct ccatagaaga tcgtccattt cttgacaagg gaatggaatg gataaagaag
    33841 gtagaagata gctatgctcc ttttttaact ccttttatca atcctcatca ggagaagcta
    33901 ttaaagattt tggccaaaac ctatggtctt gcttgtagca gtagtgggga attcgtctcg
    33961 agtgagtatg ttcgagtttt attataccca gattatttcc aaccagagtt ttcagatttt
    34021 gaaatatctc tccaggaaat tgtgtattcc aataaatttg aacatttaac gcatgctaag
    34081 attttaggga cagtcatcaa tcaattaggg attgaacgga aactttttgg agatatccta
    34141 gtagatgaag aacgggcgca gattatgatt aatcagcagt ttcttcttct ctttcaagat
    34201 ggactaaaga aaattggtcg tatacctgtt tcgctggagg aacgtccttt caccgagaaa
    34261 atagataagc tagaacagta tcgagaactg gatttatctg tgtctagttt tcgattagat
    34321 gttcttttat caaatgtttt gaaactatct aggaatcaag caaaccagtt gattgaaaag
    34381 aaacttgtcc aagtaaatta tcatgtggta gacaaatcag attacactgt tcaagttgga
    34441 gacttgatta gtgtgagaaa atttggtcgc ttgagattac ttcaagataa gggacaaacg
    34501 aaaaaagaga agaaaaaaat aaccgtccag ttattattaa gtaagtgagg aatagaatgc
    34561 caattacatc attagaaata aaggacaaga cttttggaac tcgattcaga ggttttgatc
    34621 cagaagaagt cgatgaattt ttagatattg tggttcgtga ttacgaagat cttgtgcgtg
    34681 cgaatcatga taaaaatttg cgtattaaga gtttagaaga gcgtttgtct tactttgatg
    34741 aaataaaaga ttcattgagc cagtctgtat tgattgctca ggatacagct gagagagtga
    34801 aacaggcggc gcatgaacgt tcaaacaata tcattcatca agcagagcaa gatgcgcaac
    34861 gcttgttgga agaagctaaa tataaggcaa acgagattct tcgtcaagca actgataatg
    34921 ctaagaaagt cgctgttgaa acagaagaat tgaagaacaa gagccgtgtc ttccaccaac
    34981 gtctcaaatc tacaattgag agtcagttgg ctattgttga atcttcagat tgggaagata
    35041 ttctccgtcc aacagctact tatcttcaaa ccagtgatga agcctttaaa gaagtggtta
    35101 gcgaagtact tggagaaccg attccagctc caattgaaga agaaccaatt gatatgacac
    35161 gtcagttctc tcaagcagaa atggaagaat tacaagctcg tattgaggta gccgataaag
    35221 aattgtctga atttgaagct cagattaaac aggaagtgga aactccaact cctgtagtga
    35281 gtcctcaagt tgaagaagag cctctgctca tccagttggc ccaatgtatg aagaaccaga
    35341 agtagctcca gtgcatccga caggtccaac accagctaca gaaactgttg attcagcacc
    35401 aggatttgaa gcaccgcaag aatccgttac aattttataa gaaacgatgt gagaacaata
    35461 tcttatcctt atatttccag cgagcaggag atggtgtgag tcctgcattc cctaacgata
    35521 agattatcct ctcaaaaact caagtctgaa tctagtaaga tttgacgttt cccacgttac
    35581 gggataagag ggagaaagac taaatctttt tccgaataaa ggtggtacca cgattttcgt
    35641 cctttttgga agtcgtggtt tttaatttgt tattatttat aaaggagata ccatgaaact
    35701 aaaagatacc cttaatcttg ggaaaacagc tttcccaatg cgtgcaggcc ttccgaccaa
    35761 agagccagtt tggcaaaagg aatgggaaga tgcaaaactt taccaacgtc gtcaagaact
    35821 aaatgaaggg aaaccgcatt ttgtcttgca tgatggccct ccatacgcaa acggaaatat
    35881 ccacgttgga catgccatga atcatatctc aaaagatatc atcattcgtt ctaagtctat
    35941 gtcaggtttt aacgcacctt atatcccagg ttgggatact catggtctgc caatcgagca
    36001 agttttggca aagcaaggtg tgaagcgcaa agaaatggac ttggttgagt acttgaaact
    36061 ctgtcgtgag tacgctcttt ctcaagttta taaacaacgt gatgatttca aacgcttggg
    36121 gatgtcaggt gactgggaaa atttatatgt gactttaact ccagactatg aagcagccca
    36181 aatccgtgtc tttggtgaga tggctaataa gggttatatc taccgtggtg ctaagccagt
    36241 ttactggtca tggtcatctg agtcagccct tgccgaagcg gaaattgaat accatgattt
    36301 ggtttcgact tcactttatt atgccaataa ggtaaaagat ggcaaaggta tcctagatac
    36361 agatacttat atcgtagtct ggacaacaac tccatttacc atcacagctt ctcgtggttt
    36421 gactgttggt gcagatattg attacgtttt ggttcaacct gctggtgaaa ctcgtaagtt
    36481 tgtcgttgct gcagaattgt tgactagctt gtctgagaaa tttggctggg ctgatgttca
    36541 agtgttggca acttaccgtg gtcaagaact caaccacatc gtaacagaac acccatggga
    36601 tacagctgta gatgagttgg taatccttgg tgatcacgtt accactgact ctggtacagg
    36661 tatcgtccat acagcccctg gttttggtga ggacgactac aatgttggta ttgctaatgg
    36721 tcttgaagtc gcagtgactg ttgacgaacg cggtatcatg atggcgaatg ctggtcctga
    36781 gtttgaaggt cagttctacg acaaggttgt accaactgtt attgaaaaac ttggtaacct
    36841 ccttctagcc caagaagaaa tctctcactc atacccattt gactggcgta ctaagaaacc
    36901 aatcatctgg cgtgcagttc cacaatggtt tgcctcagtt tcaaaattcc gccaagaaat
    36961 cttggatgct attgataaag ttaaattcca tacagaatgg ggtaaagtac gtctatataa
    37021 tatgattcgt gaccgtggtg actgggttat ctctcgtcaa cgtgcttggg gtgttccact
    37081 tccaatcttc tatgcagaag acggtacagc tatcatgaca gctgagacta ttgaacatgt
    37141 ggcgcaactc tttgaagtac atggttcaag catttggtgg gaacgtgatg ccaaggacct
    37201 cttgccagaa ggatttacac atccaggttc tccaaatggg gagttcaaga aagaaacaga
    37261 tattatggat gtatggtttg actcaggttc atcatggaat ggtgttttgg taaatcgtcc
    37321 aaatctgact tatccagctg acctttacct tgaaggttct gaccaatacc gtggttggtt
    37381 caactcatca ctcattacat ctgttgccaa ccatggcgta gcaccttaca aacaaatctt
    37441 gtcacaaggt tttacccttg atggtaaagg tgagaagatg tctaaatcac ttggcaatac
    37501 cattgctcca agtgatgttg aaaaacaatt tggtgcagaa atcttgcgtc tctgggtaac
    37561 aagtgttgac tcaagcaatg acgtgcgtat ctctatggat attttgagcc aagtttctga
    37621 aacttaccgt aagattcgta acactcttcg tttcttgatt gccaatacat ctgactttaa
    37681 cccagctcaa gatgtagtcg cttacgatga gcttcgttca gttgataagt acatgacgat
    37741 tcgctttaac cagcttgtca agaccattcg tgatgcctat gcagactttg aattcttgac
    37801 gatctacaag gccttggtga actttatcaa cgttgacttg tcagccttct accttgattt
    37861 tgccaaagat gttgtttaca ttgaaggtgc caaatcactg gaacgccgtc aaatgcagac
    37921 tgtcttctat gacattcttg tcaaaatcac caaactcttg acaccaatcc ttcctcacac
    37981 tgcggaagaa atttggtcat atcttgagtt tgaaacagaa gacttcgtcc aattgtcaga
    38041 attaccagag gctcaaactt ttgctaatca agaagaaatc ttggatacat gggcagcctt
    38101 catggacttc cgtggacaag ctcaaaaagc cttggaagaa gctcgtaatg caaaagtaat
    38161 cggtaaatca cttgaagcac acttgacagt ttatccaaac gaagttgtga aaactctact
    38221 cgaagcagta aacagcaatg tggctcaact tttgatcgtg tcagacttga ccatcgcaga
    38281 aggaccagct ccagaagctg cccttagctt cgaagatgta gccttcacag ttgaacgcgc
    38341 tgcaggtgaa gtatgtgacc gttgccgtcg tattgaccca acaacagcag aacgtagcta
    38401 ccaggcagtt atctgtgacc actgtgcaag tatcgtagaa gaaaactttg cagatgcagt
    38461 cgcagaagga tttgaagaga aataagattg aaaagtctag gcaaaattca atttgagaag
    38521 aaaagacaac taattttata gtctattaaa cgcattgtat cacgtttttg aacacctgat
    38581 atgatgcgtt ttttattttt aaaatttgca aggtgtgact ttttatactc atactcaatg
    38641 aaaatcaaaa agcaaactag gaagctagcc gcaggctgct caaaacactg ttttgaggtt
    38701 gtagataaga ctgacgaagt cagtaacata tatatggtaa ggcgacgctg acgtggtttg
    38761 aagagatttt cgaagagtat caacaagaat caaagagaaa cttagcaagc taacagtagt
    38821 aagataaaat aggaatttga tattagggat aagattggta aatagtgtaa tatttttaca
    38881 acaataaatt tatatagtta tttctggttt ctgaaaagta ttatattata ttttatttca
    38941 tattatacaa atttttattt tataatatca gaaaatactt tttttaaaaa gcaaatatga
    39001 tataatttta tttgaaaaaa aataaaaaag gagattttat tatgaaatca agtggtatcg
    39061 tcggtcttgt gggaggaatt ttacttctta tttgtccttt tgtcttgttg ggaacagcgg
    39121 taaatacagc tgctacaact cttaatggag gagctactgc aggggctttt tcaggtgttg
    39181 ccttactctt gaataccttg aagattgcaa atcttgttct tggtatcatt gctattgttt
    39241 actataaagg agataagcat gtaggtgcag ctccgtctgt actaatgatt gtttctggtg
    39301 aagttagtct cattccattc ttaggatggg ttggggggat tcttgctatt atcggaggat
    39361 ctctattcct tgcaacattg aagaaattca aatcagaaga ataaaaggta ttttagcatg
    39421 aaaagaacaa aaaagtttat cggtatagga gtagctctat tatctctttc tcttctagtt
    39481 gcatgtggaa cataaagttc aaagaatact tcaacaagta atgatgagaa gacagtagca
    39541 acatccaata gttcaaaaga aacaatcact ttcgatacac cggttgtaac agacgatgcg
    39601 attgaatcaa tacgcactta tgcagattat atagatcttt ataaaaatat ttttgatgat
    39661 tattttacta aagctgagga aggtttcaaa ggcacagcta tggaaaataa tgactcgttt
    39721 actaaactaa aagagtcaac tcaaaaatta ttcgatgcgc agaaaaaaag gttaaataaa
    39781 tgaagataga atagaaacaa ccaaaaacaa tgtgattgcc aaacattgtc aaacagtcct
    39841 ttcctttttg gttttgacta gcttttttgt gaaaaattgt gtaaaataga atagataaac
    39901 gaggggaaac ctcggaaaat ttaaaggaga atccatctaa tggtaaaatt ggtttttgct
    39961 cgccacggtg agtctgaatg gaacaaagct aaccttttca ctggttgggc tgatgttgat
    40021 ttgtctgaaa aaggtacaca acaagcgatt gacgctggta aattgatcaa agaagctggt
    40081 atcgaatttg accaagctta cacttcagta ttgaaacgtg ctatcaaaac aactaacttg
    40141 gctctcgaag cttctgacca attgtgggtt ccagttgaaa aatcatggcg cttgaacgaa
    40201 cgtcactacg gtggtttgac tggtaaaaac aaagctgaag ctgctgaaca atttggtgat
    40261 gagcaagttc acatctggcg tcgttcatac gatgtattgc ctccaaacat ggaccgtgat
    40321 gatgagcact cagctcacac agaccgtcgt tacgcttcac ttgacgactc agttatccca
    40381 gatgctgaaa acttgaaagt gactttggaa cgtgctcttc cattctggga agataaaatc
    40441 gctccagctc ttaaagatgg taaaaacgta ttcgtaggag ctcacggtaa ctcaatccgt
    40501 gcccttgtaa aacacatcaa aggtttgtca gatgacgaga tcatggacgt ggaaatccct
    40561 aacttcccac cattggtatt cgaattcgac gaaaaattga acgtcgtttc tgaatactac
    40621 cttggaaaat aaaaaattgt aagtctagaa ttgatttcta ggctttttat gttagtatgg
    40681 aagtatgata aggaataaaa aacaagatta tgtactggcc tacaagcaac cagcttcaac
    40741 cacttacatg ggttgggagg aagaagcttt accgataggc aatggttctt taggagcaaa
    40801 agtatttggc cttatagggg ctgaacggat tcaatttaat gaaaaaagtc tctggtctgg
    40861 aggtccactt cctgatagtt cagattatca gggtggaaat cttcaggatc agtatgtttt
    40921 tttagctgag attcggcagg ctttggagaa gagagattac aatctggcta aggaactggc
    40981 tgagcagcac ctaattgggc caaaaacgag tcaatatggg acctatctgt cttttgggga
    41041 tattcacatt gagttcagcc agcaaggtac gactttgtct caggtgacgg actatcagag
    41101 acagttgaat attagtaagg cacttgcgac gacttcttat gtctataagg gaacgcgatt
    41161 tgaacgtgaa gcttttgcga gttttccaga tgatctcttg gttcaatgtt ttactaagga
    41221 agggttggaa actctagatt ttactataga actatccttg acctgtgatt tggcttctaa
    41281 tggaaagtat gagcaggaaa aatctgatta caaggagtgt aagttggata ttactgattc
    41341 tcatatcttg atgaagggaa gagttaagga taatgatctg cggtttgcta gttatctagc
    41401 ttgggaaacg gatggagata ttagagtttg gtcagatagg gttcagatat caggagccag
    41461 ttatgccaat ctcttcttgg ccgctaagac ggattttgcc caaaatcctg ctagcaatta
    41521 tcgcaagaaa ctagatttag agcaacaggt gatagacttg gtggacacag ctaaagaaaa
    41581 gggctatacc caattgaaat caaggcatat cgaggactac caagccttat tccagcgtgt
    41641 tcaattggat ttggaagctg atgttgacgc atccactaca gatgatttgt taaaaaatta
    41701 taagccacaa gaagggcagg ctttggagga gctgttcttc cagtatggac ggtatttatt
    41761 gattagttcg tccagatact gcccagatgc tctaccagct aacctacagg gagtctggaa
    41821 tgcggtcgac aatcctcctt ggaattcgga ctatcactta aatgtcaatc tgcagatgaa
    41881 ttattggcca gcctatgtta ccaatcttct agagacggtc tttccagtca tcaattatgt
    41941 agatgatttg cgtgtctatg gtcgtctagc ggctgtaaag tatgcaggaa tcgtctctca
    42001 gaaaggtgag gagaatggtt ggttggttca tactcaagcg actccctttg gttggacggc
    42061 acctggttgg gattactatt ggggttggtc accagctgcc aacgcgtgga tgatgcaaac
    42121 cgtttatgaa gcctattcat tttataggga ccaagactat ctcagggaga aaatttatcc
    42181 catgttgagg gaaacggttc gtttttggaa tgccttttta cataaggatc agcaggcgca
    42241 gcgttgggtg tcttctccgt cttattcccc agaacatggg ccgatttcga ttggcaatac
    42301 ctatgaccaa tctctgattt ggcagttatt tcatgatttt attcaggctg ctcaggaatt
    42361 gggactggat gaggacttgt tgactgaggt taaggagaag tctgatttac taaatccttt
    42421 gcaaatcact caatctggtc gaatcaggga gtggtatgag gaggaagagc agtattttca
    42481 aaatgagaaa gtggaggccc agcatcggca cgcttcccat ctagtgggac tctatcctgg
    42541 caatctcttt agctacaagg gacaagagta tattgaagcg gcgcgtgcta gcctcaatga
    42601 tcgtggagat ggcggcacag gctggtccaa ggctaataag atcaatctct gggcgcgttt
    42661 gggagatggt aatcgagccc ataaattatt ggcagagcag ttaaagacat ccaccttgcc
    42721 aaatctttgg tgtagccatc ctccttttca gatagatggt aattttggtg ctactagtgg
    42781 catggcagaa atgttactcc agtctcatgc agcttatctg gtacctctag ctgccttacc
    42841 tgatgcttgg tcaacaggtt ctgtttcagg cttaatggca cgtggacatt ttgaagtgag
    42901 catgagctgg gaagataaaa aactcttaca gttgaccatt ttatcaagga gtggaggaga
    42961 tttgcgagtt tcttatccag atattgagaa gagtgtgatt aaaatgaatc aagaaaaaat
    43021 aaaagcgaaa tgcatgggga aagattgtat ttcggtggca acagcagaag gtgatcttgt
    43081 tcaattttat ttttaagaag atgttataag gcagtaattt gaaactgcct tttaataagg
    43141 atttaagaat gtaagcagtt tccaactagt tgaaaaagcg ttataatgat aataggaagt
    43201 aatactcaat gaaaatcaaa gagcacaaac taggaagcta gccgcaggtt gctcaaaaca
    43261 gtgttttgag gttgcagatg gaagctgacg tggtttgaag agagattttc gaggagtata
    43321 atttgtttga tagagggtgg gtctgatggc ttatattgag atgaaacact gttacaagcg
    43381 ttatcaggtt ggggacacgg agattgtggc caatcgtgat gtgaattttg agattgaaaa
    43441 gggggagctg gttattatcc ttggtgcttc aggtgcaggt aagtcaacag ttcttaacct
    43501 tcttggggga atggatacca atgatgaagg ggaaatctgg attgatggtg ttaatattgc
    43561 ggattatagt tcccaccagc gcaccaatta ccgtagaaat gatgtggggt ttgtttttca
    43621 gttttataat ctagtttcta atctgacagc taaggaaaat gtggaattgg cttctgaaat
    43681 tgtgacagat gccttgaatc ctgatcaggt cttgacagat gtaggtctgg ctcatcgtct
    43741 caataacttt ccagcccagc tttctggagg ggagcaacag cgagtctcca ttgcacgcgc
    43801 ggtagccaaa aatcctaaaa ttcttctttg tgatgaacct actggagcct tggattatca
    43861 gacgggcaag caggttttga aaattctcca agatatgtct cgtcaaaagg gagcgacggt
    43921 gatcatcgtg actcataatg gagctttggc gcccattgct gatcgcgtga ttcatatgca
    43981 cgatgccagt gtcaaggatg tggtgctcaa ccagcatcct caggatattg acagtttgga
    44041 gtactagtat gatcaagcga aaaacttatt ggaaggactt aattcagtcc ttcacaggct
    44101 ccaaggggcg ttttttatcc atcttgatcc tgatgatgtt gggatctcta gccttagtag
    44161 gcctcaaagt aaccagtccc aacatggagg cgacagctaa tgcttattta acaactgctc
    44221 aaaccttgga tttggcagtc atgtctaact atggcttgga tcaagcagac caagaagaac
    44281 taaaacagac ggagggcgca gaggtcgagt ttggctattt gacagatgtg actatggata
    44341 atgggcagga tgccattcgg ctgtactcca aaccagagcg aatttcaacc tttcagctaa
    44401 gaaagggacg acttcctcag tcagacaagg aaatcgcttt ggccactcat ttgcaaggcc
    44461 aatacagcgt gggacaggag attagtttta aagaaaaaga agagggtcat tcctctttaa
    44521 aagaccatac ttataccatt actggttttg tggattcggc tgaaatcctc tcccagcgag
    44581 atatgggcta cgcaggaagt ggaagtggga ctctgacagc ctatggggtg attttaccta
    44641 gtcagtttga tcagaaagtc tacaatatag ctcgtttgaa atatcaagat ttagcaggtt
    44701 taaatgcctt ttcatcagct tatgaagaaa aatccaagca acatcaggaa gagcttgaac
    44761 aaattttatc agataatggc aaggtacgtc tgcaactttt gaaaaaagaa ggacaagagt
    44821 ctctagacaa ggggcaagag acccttgaca aggctcagac taatttgcag gaaggcaagc
    44881 gtcgtttagc agctgctcaa gctcgtatac aggctcaaga aagtcaacta gccttgtttc
    44941 ctcaagttca gagagagcag gctagtgctc aacttaccca agccaagcag gaattgggca
    45001 aggaagaggc caaactaaag caagctgaac aaaatctagc ccaagaaaat gaaaaattag
    45061 aaaaacatca gcaagtcttg gacgatttgg cggagccaag gtatcaggtc tataatcgtc
    45121 agaccatgcc aggtggtcag ggctatctta tgtatagcaa tgcttcatcc agtattcgag
    45181 cagtgggcaa tatctttcct gtggtacttt atgccgtagc agccatggtg acctttacga
    45241 ccatgactcg ctttgtagac gaagagcgaa ctcatgcagg gatttttaag gccttgggtt
    45301 atcgtagtaa ggatattatc gccaagtttc tcctttatgg actagtagct gggactgtcg
    45361 gaacggctct aggtagtata cttggtcatt atttgctagc cagtgtaatt tcaagtgtca
    45421 ttacaaaagg catggtggtg ggagaaactc agattcagtt ctattggacc tatagcttac
    45481 tagctcttgt cttgagcttg ttggcgagtg tgttaccagc ctatctggtg gcttggaggg
    45541 aacttcatga cgaagcagcc cagcttctac ttcctaaacc tcctgtcaaa ggagctaaaa
    45601 tcttattgga gcgtatcggt tttatctggc gtcgtctcag ttttactcat aaggtaacag
    45661 cccgcaacat ctttcgttat aagcagagaa tgttgatgac aatctttggt gtggcaggtt
    45721 ctgtagctct gctctttgca ggtttgggaa tccaatcttc tgtagcagga gttccgtcta
    45781 aacagtttca acaaatccaa cagtatcaga tgcttgtctc tgaaaatcct agtgcgacca
    45841 atcaggacaa ggtagagcta gcagaagtgt tgaaagggca ggagatacta gcctaccaga
    45901 aaatctattc taaaacgcta gacaaggatt tcaaaggcaa ggctggtctt caaaacatta
    45961 ctcttatgat gatagagaag gaagatttga ctccctttat ccatcttcaa catcatcagc
    46021 aggagctgac attaaaagat ggcatcgtta ttacagctaa actcgcccag ctggcaggtg
    46081 tcaaggttgg gcagacttta gaaattgaag gtaaggaact aaaggtcgct gctattactg
    46141 agaactacgt tggtcacttt atttatatga gtcaggctag ctatgagcaa ctttacggac
    46201 agctacccca agccaacact tatctggtct cattaaggga taccagtgca actagtatcg
    46261 aaagtcaggc gggcttgctt atgaatcaat ctgcggtgtc cagcgttgtc caaaatgctt
    46321 cagccattcg actcttcgac tctatcgcta gctcactcaa tcagaccatg accatcttgg
    46381 tcatcgtatc tgttctatta gctattgtca tcctttacaa tctgaccaat atcaacgtag
    46441 ctgagagaat ccgtgaactc tccactatca aggttctcgg ttttcataat aatgaagtca
    46501 cactctacat ttaccgtgag acgattgtgc tgtcccttgt gggaatcgta cttggtctga
    46561 tagctggttt ctatttacac caatttttga ttcaaatgat ttcgcctgcg actattctct
    46621 tttatccgca ggtaggctgg gaagtctatg taatcccagt ggcagcagta agcatcattt
    46681 tgaccttgct tggtttcttc gtcaattatt atctgagaaa ggttgatatg ttagaagctc
    46741 tgaaatctgt agagtaaggt agttattttt agctgattga acttctattt actaatattc
    46801 aaaaatcctc cgtttcaaag agcagggaac tctttgtgac agaggatttt ttctataggg
    46861 ctttagcagc tgcaattgcg gcttcgaagt ttggctcaga attgatatta tccacgtatt
    46921 caacgtagcg aatcgtattg tcagtatcga ggacaaagac tgcgcgtgct aataggtgcc
    46981 attcgttgat taagagggca taatcgtgcc cgaaagaatg gtcaaagtag tctgaaagca
    47041 taatggcatt gtcaaggcct tcagcaccgc accaacgttt ttgagcaaaa ggtaggtcca
    47101 ttgaaacagt caatacgacc gtgttgtcca gtccagccaa ttcttcatta aaacgacgtg
    47161 tttgagttga gcagatgcct gtatcgatag aaggaacgac actcaagact tttttcttgc
    47221 catcaaaatc agccagagat tttttagaaa gatctgttgt agtaagagaa aaatcaagcg
    47281 ccttgtcgcc aacttgtagt tgtttacctg taaagctcac aggatttccg agaaaagtta
    47341 ccataggata ctccaatctt ttttcttcca ttgtatctga aacagtcaga attttccaat
    47401 gatttgaccg gaaatgtggg catagaaaaa acgccagctc acatgagaat gacgtttttc
    47461 agaggcttat tttgccaatc cttcagcaat cttgtcaagg ttgtatttca tcatgctgta
    47521 gtagctgtcg ccttctttac cttgttctgc gatagagtca gtaaagattt gtgcgtagat
    47581 tgggatgttt gtgtcttgag aaacagtttt cattggacgg tcatccacac ttgattctac
    47641 aaagagtgat ggaacttttg tttggcgaag tttttcaacc aaggtcttga tttgttcagg
    47701 agttccttct tcttcagtat tgatttccca gatgtaggca cttgggacac cataggcttt
    47761 agagaagtat ttgaatgctc cttcgctggt tacaatgagt ttcttttcag cagggatctt
    47821 attaaattta tccttacttt ctttatcaag tttgtctaac ttatcagtat attctttgag
    47881 atttttttca tagaattctt tattgttagg gtctttggcg ctcaattgtt tggcgatatt
    47941 tttagcaaaa ataataccgt tttcaaggtt aagccaagcg tgtgggtctt cttttccttt
    48001 ttcattttga ccttcaaggt agataacatc aacgccgtcg ctgactgcga agtagtcttt
    48061 gttttcagtt ttcttggcat tttctaccaa ttttgtaaac caagcattgc cacctgtttc
    48121 aaggttgata ccgttataga aaatcaaatc agcctcagaa gttttcttaa cgtcttcagg
    48181 aagtggttcg tattcgtgtg ggtcttgccc aatcggaacg atactatgaa ggtcaatttt
    48241 gtcaccagca atatttttag taatatcagc gatgattgag tttgtagcaa caacttttag
    48301 tttttgacca gaagttgtat ctttttttcc gctagcacat gctacaagaa tgattgcaga
    48361 aagaaagaga acgagtaatg tacctaattt tttcattaga tcctccaatt tattagggct
    48421 ttgcccctta ttttaacaaa tgtttatttt tcagtttcaa atatcgttgt ttgggagcga
    48481 taaagaagct aatgagaaag aaactagcag ctgtaagcac gatactagaa cctgccgcaa
    48541 cattaaaact atagccaata aagagtccca aaactgaagc agtagctccg aaggttgagg
    48601 aaaggaaaat catacttttc agactattag catacagata agcagttgca gctggggtaa
    48661 tcagcatggc tacaatcagg atagttccga cactttgcat ggctgtcaca gacacgagag
    48721 tcaggagtac catgagaagg tagtgataga aattgacagg cattcccatg gctttagcca
    48781 agagttcatc aaaggaagtt atcaagagtt gcttgaagaa aatccaaatt aacaagagga
    48841 tggctgcccc cacacccata gtaataaaca tatccgtatc ttggacggcc aggatattac
    48901 caaaaaggat atggaaaagg tcagttgaac ttttagcgac accaatcaag atgataccga
    48961 gggctaagaa agaagaaaag gtaatgccga tggcggtatc gcttttgata atcgagtttc
    49021 ctttgatgta ggtaatgatg atggcagcta gcaatccaaa gacaatggct ccgataaaga
    49081 agtcaaggcc caagatgaag gagagggcta cacctggtaa gacagcatgt gaaatggcat
    49141 ctcccatgag tgacatcccg cgtagaataa tgaaacatcc cacggctcca gctacaatcc
    49201 cgacgacaat agctgttatc aaggcatttt gtaggaaatg gaatttttgc aatccatcga
    49261 taaattctgc aatcataggt cacctccatt gaaaaagagt tgattaccgt aagcttcttt
    49321 tagattggtt tcggtaaaag tttcttttgt tggaccaaag gcaatcactt ctcgattgac
    49381 aagtaagact tgatcgaagt agtggggaat cttgctgagg tcgtggtgaa cgatgagaac
    49441 cgtcttccca gcttttttca aatctctcag cgtattcatg atgatttcct cactgacaga
    49501 gtcaatccca gcaaagggtt catccaagag gatatagtcg gcttcctgca ccaaacatct
    49561 ggcaatcaag acccgctgga attgacctcc agacagttga ctaatttgac gttcagcgta
    49621 gtcagctagg ccgacgattt caagggcctc ttgcactttc ttccaatgtt tagcctttaa
    49681 acttcgaaag agaggaatag agggaaatag tcctaacgag acgcattcct tgaccttgat
    49741 gggaaagttg tagtcgatat tgattttttg ttcgacatag gcaattcggt gtaaggattt
    49801 tttaacttcc ttgtcatcga gaaatgcctg accttgatgt gggataattc ccaacatacc
    49861 ttttaatagt gttgatttcc cagcgccgtt tggaccaatg atgccggtaa ttgttggtcc
    49921 atggagcact agtgaaatat ccttaagtgc caacgtttct ttgtaggaga cactgaggtt
    49981 ttcgatacgt atcataaact tgtattcctc ctgtctctta atatacatta aaaaaaaaat
    50041 taagtcaagt taatttttga aaaaattaaa ataataactg aaaaatagat tctaaaaata
    50101 actttcagga taaatttcta aattataaaa cgcatagtat caagtgtaaa aaacttggaa
    50161 ttatgcgttt tatcatggaa aggtttttta taatagctaa aaaataatag ttaaatggtt
    50221 attaattgca ttccctagtg atttttgtta agataaaggc aaatacaaat gaaagcgaga
    50281 acaagatgac acgttatcaa gatgattttt atgatgctat caatggagaa tggcaacaga
    50341 cagctgaaat cccagcagat aagtctcaaa caggaggttt tgttgattta gaccaggaaa
    50401 ttgaagacct gatgctggcg acaacagaca agtggttagc aggtgaagaa gtgcctgagg
    50461 atgctatctt ggaaaacttt gtcaaatacc accgcctagt tcgtgatttt gacaagagag
    50521 aagctgacgg tatcacacct gtcttaccac tccttaaaga attccaagaa ttggaaactt
    50581 ttgcggattt tacagctaaa ctagcagagt ttgagcttgc aggaaaacca aacttccttc
    50641 cttttggtgt atcgccagac tttatggatg ctagaatcaa tgttctatgg gctagcgctc
    50701 caagcacaat cttgccagat acgacctact atgcagaaga acatcctcag cgcgaagagc
    50761 tcttgactct ttggaaagaa agtagcgcaa atctcctcaa ggcttatgat ttctctgatg
    50821 aagaaattga agacttgcta gaaaaaagac ttgaattgga ccgccgagtt gcggcagtgg
    50881 tgctctctaa tgaagaacgt tcagaatatg ctaaactcta tcatccatat tcttacgaag
    50941 atttcaagaa attcgcgcct gccctacctt tggatgactt cttcaaagca gttattgggc
    51001 aattaccaga caaggttatt gtagacgagg aacgtttctg gcaagcagca gagcaatttt
    51061 acagtgagga agcctggtct ctccttaaag caaccttgat tttgagtgtt gtcaatcttt
    51121 caaccagcta tttaacagag gatatccgtg ttttgtctgg tgcctacagc cgtgcccttt
    51181 ctggagttcc agaggcaaaa gataaggtca aagcagctta tcatctagca caggaacctt
    51241 tcaagcaagc cctggggctt tggtacgccc gtgagaagtt ctctccagaa gccaaggcgg
    51301 atgtggagaa aaaagtggca accatgattg atgtctataa ggagcgtctg cttaagaatg
    51361 actggctcac tccagaaacc tgtaaacagg ctatcgtgaa gctcaatgtg atcaaacctt
    51421 atattggcta tccagaagaa ttgcctgcac gttacaagga taaggtagtg aatgaaactg
    51481 ccagtctttt tgagaatgct ctagcctttg cgcgtgtgga aatcaagcac agttggagta
    51541 agtggaacca gcctgtagac tataaggaat ggggcatgcc tgctcatatg gtcaatgcct
    51601 actacaatcc tcagaagaac ctgattgtct ttccagcggc cattttacag gcgcctttct
    51661 atgacttgca tcagtcatct tctgctaact acggtggtat tggggcagtg attgcccatg
    51721 aaatttccca cgcctttgat actaacgggg cttcctttga cgaaaatggt agcctcaagg
    51781 attggtggac agagagcgac tatgctgcct tcaaggagaa aacacaaaaa gtcattgacc
    51841 aatttgatgg acaggattct tatggagcaa ccattaacgg taaattgact gtatcagaaa
    51901 acgtggctga cttgggagga atcgcagcag ctcttgaagc agctaagaga gaagcagact
    51961 tctcagcaga agagttcttc tacaacttcg gtcgcatctg gcgcatgaaa ggtcgaccag
    52021 aatttatgaa acttttggct agcgtcgatg tgcacgcacc agccaaactc cgtgtcaatg
    52081 tgcaagtacc aaacttcgac gatttcttta caacctatga tgtcaaagaa ggagacggaa
    52141 tgtggcgttc accagaggag cgcgtgatta tttggtaatg caaaaaatct agtcatcaga
    52201 aaaaaggcat ccaatcacgt gtgaaaacct tgataggatg ccttttataa tagaaagatt
    52261 tgctggatag tttacttaaa tttcgattgt catcatcttg ctaaaaaaag ggattgaagg
    52321 ctttttcgtg agcgatagta gtagctggac catgtcctgg atagacatcg tagtttggta
    52381 gggtgaagag ttgggtctgg atactatgaa ggagttgctc catgctacca gtcggaaggt
    52441 cggtccgtcc gatagtttcg cggaatagag catctcccgt caagactagg taagcatcag
    52501 gaaagactag ggaaacacca ccgatagagt gccctggggt cggtagaacc ttaaaacgaa
    52561 attcctctag ttggtattct tcgtgaaaga caaaggtgtg ttctgcaggt tttgtgacca
    52621 catctgccat atcatcgtgg cgagggagac cggagagatt atcgacagga gtgtagagcc
    52681 agctggcttc gctctctgcg atatagacag gaggattgcc aaacgtctcg cgaaccaagt
    52741 ccagactcat gatatggtca taatgggcgt gggtcaagag aatagcacag atcggtttgt
    52801 tgatcttctc gattgtctga cgaatggctt cccaatgact accaggatcg acgacgatga
    52861 ggtgcttttc gccttctaga taataggtat tttcataggc aacaggattc acggttttat
    52921 ggattttcat actagctcca atctcaaaga atgtactaat actcttcgaa aatctcttca
    52981 aaccgcgtca actttatctg caacctcaaa gcagtgcttt gaacagcctg cggctagctt
    53041 tctagtttgc tctttgattt tcattgagta taaattaagt atagcacagt tagggagaat
    53101 aggtaaggat ttaaaatgaa cttaaaaatc agcatgacta gatgaagaca ggctggttat
    53161 caatttatca atattggaaa ggtgtcaatt gcccttcata ggttgcataa actccgtcat
    53221 tagcttgttt gatagacgtg atgtttagag tgctaccgta gttggcttct catttgtcgc
    53281 tatattcact ataagttatc ctactgggca ggttctggtc gttagcatag tattgaacga
    53341 gttttttata gctttgctgg ctgaatagga acaggcagca aactcctaac attaggagag
    53401 caaagataga aatagcagtt tttttcatag gtattctcct tataaactaa aggatagaag
    53461 aaagtatctt gaggattttt atactcttca aaaatctctt caaaccgcgt caactttatc
    53521 tgcaacttca aagcggtgct ttgagtaacc tgcggctagt ttcctagttt gctctttgat
    53581 tttcatttag tattaattcc aaaatccagt caaggtacca gtgtatgtgc tacgagttcc
    53641 accgtttatc tttcgtattt tcaatggaat tggggaagtc agaaagtctt tgggttacaa
    53701 tatggtttcc gttcttctat ctctccttct atcacctaag tttaaaatct aacttcgtag
    53761 tatattatgg gctaataatt cagaattatc aagcaatttt gaattatttt tttcttattc
    53821 tgttccaatc tagttttcat attcttaaaa aagtgataaa atggtaggaa gaattggaga
    53881 gtagagatgc cgaaagaagt gaatttaaca ggcgaagaag ttgtcgcttt aaccaaagaa
    53941 tatttaacgg aagaggatgt tcattttgtc cataaggcct tggtctatgc tgttgaatgc
    54001 cacagtggtc aatatcgcaa atcaggcgag ccttatatca ttcaccctat ccaagtggca
    54061 ggtattttag ctaagctaaa gctggatgct gtaacagtag cttgtggatt cttgcatgat
    54121 gtggtggaag atacagatgc gactttggac gatttggaaa gagagtttgg tcctgatgtg
    54181 cggatgattg ttgacggagt taccaagctt ggcaaggtcg agtacaaatc gatcgaggag
    54241 caattagcgg aaaatcatcg caagatgctc atggccatgt ctgaggacat ccgcgttatt
    54301 ttggtcaaac tgtctgaccg cttgcacaat atgcggaccc tgaaacatct tcgaaaagac
    54361 aagcaggagc gtatttccaa agaaaccatg gaaatctatg ccccacttgc ccatcgtttg
    54421 gggatttcca gtgtcaaatg ggaattagaa gacttgtctt tccgttatct caatccaacg
    54481 gagttttaca agattaccca tatgatgaag gaaaagcgca gggagcgtga ggccttggtg
    54541 gatgaggtag tcacaaaatt agaggagtat acgacagaac gtcacttgaa agggaagatt
    54601 tatggtcgtc ccaagcatat ttactcaatt ttccgcaaaa tgcaggacaa gagaaaacgg
    54661 tttgaggaaa tctatgatct gattgctatt cgttgtattt tagataccca aagtgatgtt
    54721 tatgccatgc ttggttacgt gcatgaattt tggaaaccga tgccaggtcg cttcaaagac
    54781 tatattgcca accgcaaggc caatggttat cagtctatcc atacgactgt ttatggacca
    54841 aaagggccga ttgaattcca gattcgaacc aaggaaatgc acgaggtggc tgagtacggg
    54901 gttgcggctc actgggctta taagaaaggt ataaaggggc aagttaacag caaggaatca
    54961 gctattggaa tgaactggat caaggagatg atggagctcc aagaccaggc tgatgatgct
    55021 aaggaatttg tggactctgt taaggaaaac tatttggctg aggagattta cgtttttacc
    55081 ccagatggag ctgtccgttc ccttcccaaa gattcaggac cgattgattt tgcctacgaa
    55141 atccatacca aggtcggtga aaaagcaact ggtgccaagg tcaatggccg catggttcca
    55201 ctgacaacca agttaaagac aggggatcag gttgaaatta tcgccaaccc gaactccttt
    55261 ggacctagcc gtgactggct caatatggtc aagactagca aggcgcgcaa taagattcgc
    55321 cagttcttta aaaaccaaga taaggaattg tctgtcaaca agggtcgtga gatgctgatg
    55381 gctcagttcc aagaaaatgg ctatgtggca aataaattta tggacaagcg ccacatggat
    55441 caagttctgc aaaagaccag ttacaagaca gaagactccc tctttgcggc cattggtttt
    55501 ggggaaatcg gtgcgattac cgtctttaac cgtctgactg aaaaggaacg ccgtgaggaa
    55561 gagcgtgcca aggccaaggc tgaggcagag gagcttgtca aaggtggcga ggtcaaggtt
    55621 gaaaataaag aaactctcaa ggtcaagcat gaggggggag tggttattga aggtgcttct
    55681 ggtctcctag tgcggattgc taagtgttgt aaccccgtgc ctggtgacga tattgttggc
    55741 tacattacca agggtcgtgg tgtggctatt caccgtgtgg actgtatgaa cctgcgtgcc
    55801 caagaaaact acgagcaacg tctccttgat gtggaatggg aagaccagta ctctagctca
    55861 aataaggagt atatggccca tatcgatatc tacggtctca accgtacagg actgttgaac
    55921 gatgtactgc aagttctttc aaatacaacc aagaatattt caacggtcaa tgcccaacca
    55981 accaaggata tgaagtttgc taatatccat gtgtccttcg gtattgccaa cctctctaca
    56041 ctgaccacgg ttgtcgataa aattaagagt gtgccagaag tttactctgt caaacggacc
    56101 aacggctagt tgtcctagct cttactagaa aggctattat gaaaatcatt atccaacggg
    56161 ttaaaaaagc ccaagtgagt atagaaggcc agattcaggg aaaaatcaat cagggacttt
    56221 tattgctggt tggtgttgga ccagaggacc aagaggaaga tttggactat gctgtgagaa
    56281 aactggtcaa tatgcggatt ttttcagacg cagaaggcaa gatgaacctg tctgtcaaag
    56341 atattgaagg agaaatcctc tctatttctc agtttaccct ctttgcggat actaagaaag
    56401 gcaatcgtcc agcctttaca ggggcagcta aacctgatat ggcatcagac ttctatgatg
    56461 ctttcaatca aaaattagcg caagaagtgc ccgttcagac aggtatcttt ggagcagata
    56521 tgcaggttga gctggttaat aacggacctg ttaccattat cctagatact aaaaagagat
    56581 aagaaagacc aagcccagtc ggcttggtct ttctcatcga tcataaaata ctccaaaaag
    56641 aaatcggttc ttgatatgct tgggggaagt ctcttttcag gctttggcag atgcgatagg
    56701 aagggatgag atgtcctagg atgaggagag ttccctgaag gaaaagtgga atatcactta
    56761 aagacaccaa ggagagaatc atcaggctat cccataggag aatttgtaaa gcaaaacgtc
    56821 agaatctcgg tctaatctgg gaatagagtt gactaaagtg gtcacaaagt tggtttgaaa
    56881 gataggtcaa tagcacagga tgaaagaaaa tgagccaacc actataaatc aaaatccagt
    56941 cccaagtaag cccccctttt aaatgtcaaa aatgccagca tgattccatc aatgacaagg
    57001 agttgaatgg ttttgatgaa gatgattttt ttcatgctaa aacctccttt tttcatctgt
    57061 tagtgacgta atgctttata taattattat acagtattca gtcgggatat gaaaacgttt
    57121 actatcgttt ttgatataaa aaatagataa gaaaaccctg aaaataaaac tttcagggtt
    57181 ggtaggggac ttgagaaatt agttgatttt ctcgacatag agttgttttg caatgtccat
    57241 attcacttgt aaatcctcgt cgttactgag gatagtgaag gtattgctga agccatcaaa
    57301 ctgcttgact tggagctggt caccgatgtg aagtgagtgc ttgtccagat aatggagaat
    57361 gtcaaaacta tcgtgcaccc gagtcaggcg gtaggcgcca gcttccttga tatcagctag
    57421 tgggaggtta ttgatttcaa cgaggagttc tcccttggca ggaatagttc ctccgtgggg
    57481 gcaggtttta gggaaaccta gcagtttatc tagtctttcc acgaacaggt cagagacagt
    57541 gtgttccaag acctcagctt cctcgtgaat ctggtcactt gtatagtcta aatgatgaac
    57601 tagaaaaact tcaatcaagc ggtgcttacg atagagctca gagaccagtt tgagaccgag
    57661 gtcagtcagt agatagccac attccttgtc ctttaggatg agattttcac ttttcattcg
    57721 tttgatcatt tcagttacgg cagggggaga gacttgcatg cgagccgcaa tttccttgtt
    57781 ggtaatctta tgcaggtcta tgccaatttc ataaatacat tttagatagt cttctttgtt
    57841 tggggtcatt cgtttcctct tgtctaatat ctttatctag tatatcaaaa aaagctagat
    57901 ttctctagct gtgacttttt atgttatact tattgcaaga gaaaaaacga ggagatggat
    57961 atgacgaaaa tagctcttct ttcagatatt catggaaata ccaccgcctt ggaggctgtt
    58021 ttggcagatg ctcagcagct aggagtggat gaatactggc ttttgggaga tattctcatg
    58081 ccagggacag gacgtagaag gattttggac ttgttggatc aactaccgat tacggctaga
    58141 gttttgggaa actgggaaga cagtctttgg catggtgtcc gtaaggaatt ggacagtact
    58201 cgccccagtc aacgctatct cttgcgccag tgccagtatg ttttagagga aatttcccta
    58261 gaagaaattg aagtgctcca caatcaacct cttcaaattc atcgtcagtt tggggatttg
    58321 acggtgggaa ttagccatca tctgcctgat aagaactggg ggcgagagtt gattcatact
    58381 ggcaaacaag aggagtttga ccgcttggtg actcatcctc cctgtgatat tgctgtttat
    58441 ggacatattc accagcagtt gcttcgttac gggactggtg ggcaattgat tgtcaatccg
    58501 ggttcgattg gccaaccttt ctttttggac gctcagctac ggaaggactt gcgggcccag
    58561 tatatgattt tggagtttga tgacaagggt ctggtagata tggacttccg acgggtagac
    58621 tacgatgtgg cagcggaatt gcagctggct aaagacctga gacttcccta ttttgaggtt
    58681 tactatgaaa gtctggtcaa tgggatccac catactcatc atcaggaatt tttgagagaa
    58741 ttggctcaga aagagggctg cgatcgggag ttagacgact ggttgaaaag tggtaacgat
    58801 tgacattaca actaaaaagg gtataataat agaaaaagaa gagtagaggc agggtagcct
    58861 cgtaaaaagg agaagaggat gcaaattcca agtagattta ccattgcgac tcatatgctg
    58921 ataatcattg ccctcgaggg gaaggaaagc aaggtgacca gtgattttct ggctgctagt
    58981 gtcggggtca atcctgtcat tatcagaaat atcttgtccc agttgaagaa ggcagagctg
    59041 atttcagtag cgcgtggaac gggcggaaca gagattgtca aggaccttaa ggatattagt
    59101 cttttagatg tttatcaggc ggtcgaatgt cttggtaaga caggtcaact cttcagtttc
    59161 catgacaatc cgaatccaaa ttgccctgta ggagctcata ttcatgatgt tttggatcaa
    59221 aaattggaga gaattcagtt gactatggag gcagaacttg gtcaaaccag tctagaaaaa
    59281 gtcgtggccg atgcagagag tcagatgaag gattaagagg gataaatgcc ctcttttttc
    59341 tttggataat tatgataaaa tgtagctatt aaaggagtaa gaaatgtatc tcgttatagg
    59401 aattgtatta gcctttatag tgtcattttg gaaggataat agaagtttgt ggaatccagt
    59461 attattttta ttatccctca tttcaagtta tttttatcta tcctaccttt tttataaaaa
    59521 tggatacgag aatgttcagt tagcttttta tgtatttacc tttgtcttac ttcctttttt
    59581 gctttttcta agtggcatct ttttaatcta taatggggtc attttgttga agtgagaggg
    59641 acgttccaag ccccattatc tctcaatgct ctttgatttt tattgactat tagattctat
    59701 ttaaaaagac ttagaatgca catgaaagta tgtattctag gtcttttgtt ttgtatacat
    59761 ttaattttca agagtattat ctatttttcc atgcctggta acgagtatca atcaataact
    59821 gggtaaggcg acccaaggtt tctctttctt ctggagtgag ggattgagct tggacaaaga
    59881 gatgatgaat gtattcaagc gcctttaagg aagccaagtc gttgatagag ctaataccag
    59941 catcaagaat agtgccaaag aagaggtcga agtagagctg aagttcttcg tcagggactg
    60001 tggccaccca ttctttaaag gttgtgtcta cttgctggct atcactgttg gtcttatcca
    60061 gttggacgaa gtgcttgtcc tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac
    60121 ccagggcagt actctgaacg atgatttggt gagcaggaat ttccagcatc ataccgataa
    60181 tggaaccttg tggaatgaat atcttgcttc tatccattat cctttgataa cccgcagtct
    60241 gtgtcaattc ttgatggaga ccaggtgcat caaatgtata aactgctgtg atctgatttt
    60301 gcaaactttg ctcaatttgg ctagcagcat agatagcgag atttcctccc ttggaatgcc
    60361 cagccagaat aaccttttgc ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg
    60421 cgtgcttttg agcaggaatt tccttcatat aggtcaggtg gaaatcttcc ttccagccaa
    60481 tgatactgtc atctgtccca cgaaagacaa tcagataggt atcgaggctg acacgataag
    60541 tcatagccgc aaattgcttt tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt
    60601 tgcaattttt gaagcgcttg tgttgagcca attcatctaa taattgaagg cgatttttgc
    60661 tagtaagcat ggtgggctct cttggaacct gaggtgctag ctctaaaaga cgttgaggaa
    60721 gtgtggagac cagattatca aaggagaggt aggtgatttc tattaaggtt agaatgtcta
    60781 actcattcaa gggaaggtcg taataagaat catatgcgac atctttcaga tagtcaaaaa
    60841 tattggccat aagagctcct ttctttttat ttatcttagc aaatttccct caaattagct
    60901 agtagcattg cctgtttgta ctggctaaaa acaggctatt tcaaattcag tttcagacca
    60961 tctggcatgg aaaaatctgt tataataatg gaaaaggaga agcgcatgca caagatttta
    61021 ttagtggaag atgatcaggt cattcgtcaa caggttggga aaatgctctc tgaatgggga
    61081 tttgaagtgg tcctggtaga agactttatg gaagttttga gtctatttgt tcagtcggaa
    61141 cctcatctgg tcctcatgga tattggtttg cccttgttta atggttatca ctggtgtcag
    61201 gaaatccgca agatttccaa ggtacctatc atgtttcttt cttcgagaga ccaggctatg
    61261 gatattgtca tggcaatcaa tatgggggcg gatgactttg tgaccaagcc ttttgaccag
    61321 caggttcttt tagctaaggt tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat
    61381 gagagtttgc tggaatatgc tggtgttatc ctcaatacca aatccatgga tttacattat
    61441 caagggcaag tcttgaattt gaccaagaac gaattccaga ttttacgcgt gttatttgag
    61501 catgcaggca acatcgtagc acgtgacgac ctgatgcgag aactttggaa cagtgacttt
    61561 ttcattgatg ataataccct ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag
    61621 cagggattgg taggatttat cgagaccaag aaaggaatag ggtacggatt gaagcatgct
    61681 tgattggaaa caattttttc tagcctatct gcgctcccgt agtcgtcttt ttgtctatct
    61741 gctttctttg gcatttctgg tcttactctt tcagttttta tttgccagtc taggaattta
    61801 cttcctctac tttttcctct tgtgttgctt tgtaaccatc ttatttttca cttgggacat
    61861 attggtggaa atgcaggttt atcgccagga acttctctat ggagagaggg aagccaagtc
    61921 tcctttggaa atagctttag cagaaaaatt agaagcgcgt gagatggaac tctatcagca
    61981 gaggtcaaaa gcagaaagaa aactgacgga tttgctggat tactatacct tgtgggtcca
    62041 tcagataaag acccccattg cagccagtca actcttagtt gcagaagtgg tcgaccgcca
    62101 actgaagcag cagctagaac aggaaatttt caaaatcgac tcctatacca acctagtttt
    62161 acagtacctg cgtttagaaa gtttccatga tgatttgctc ttaaagcagg ttcaaattga
    62221 ggacttggtc aaggaaataa ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa
    62281 tgtcaatcta catgaccttg ataaagaaat cgtgacggat aaaaagtggc tgctagtggt
    62341 tattgagcaa atcatctcaa acagtctcaa gtacaccaag gaaggtggtc tggagattta
    62401 tatggatgac caagagcttt gtatcaaaga tacgggaatc gggataaaaa acagtgatgt
    62461 cctccgagta tttgaacgtg gcttttcagg atacaatggc cgtttgaccc agcagtcctc
    62521 tggacttggc ctttatctat ctaagaaaat ttctgaagaa ctggggcacc agattcgtat
    62581 cgagtctgag gtcggaaaag gaacgacagt gcggattcag tttgctcaag tgaacttagt
    62641 ccttgagtaa aaatagatga gaaaaagcct ccagattgga ggcttttatg ctagactctt
    62701 atttctcaac gcgtgatttg ttggcgatat cagctaggat agcttgaaca aaattatcaa
    62761 ctgagacagt ttgtgtttct ttttggccgt agcgacgaac gttgactgtt tcgtcttcca
    62821 tttctttgtc tccaacaatt aattggtaag gaatcttgct ggtttgtgaa gcacggatct
    62881 tgaactgcat tttttcattg cgctcatcta catctgcacg gacaccgcgg tcacggagtt
    62941 tcttggccac ttcccaagcg tagtccacgt gtttttcgtt agatactggg atgagggtta
    63001 cttggtgtgg tgccagccat gttgggaagg cccccttgta gttctcaatc aagatagctg
    63061 tgaagcgttc catagttgag ataactccac ggtggatcat gactggacgg tgatcttcgc
    63121 catcagctcc gatgtatttg aggtcgaagc gttctggcaa caagaaatca agttggatag
    63181 tagaaagggt ttcttctttt ccaagggcag ttttaatctg gatatccaat tttggtccgt
    63241 agaaggctgc ttcaccttcg gcttcaaagt agtccacgcc catttcatca agagctgcac
    63301 gaagcatggt ttgggcattt tcccacatct catcgttatc aaagtactta tgagtatctt
    63361 gagggtcacg aagagagagg cggaagcggt agtcagtcaa gttgaagtct tcataaacat
    63421 cgataatcaa ctgaagggca cgttggaatt cttcttggat ttgttctgga gtaacgaata
    63481 ggtgaccgtc gttgagtgac atttcacgta cacgttgaag gccagtgagg gcaccagatt
    63541 tttcgtaacg gtgcatcata ccgatttcag cgatacggat tggcaattca cggtaagagt
    63601 gaacatggtg tttaaaaact tggatgtggt gcggacagtt cattggacga aggacaaatt
    63661 cttccccgtc acccatgtcc atggttggga acatgtcttc ttggtaatga tcccagtgac
    63721 cagaagtctt gtaaagctca acagaagcaa gtggtggagt gtagacgtgt tggtagccag
    63781 aagccaactc tttgtttacg atgtagcgtt ccaattcacg acggatagtc gcaccatttg
    63841 gcaaccagaa tggcaaacct tgtcccactt cttgtgaaat cataaagagg tcaagctctt
    63901 taccaagttt acggtggtca cgttccttag cttcttcacg catttgaagg tagtttttca
    63961 agtctttctt gtcaaaccaa gctgtaccgt agatacgttg catcatagcg ttgtcgctgt
    64021 ttccacgcca gtacgcacca gctacatgga gaaggtggaa gatttggata cgacctgttg
    64081 atggaacgtg aggtccacgg cagaggtcta catattcacc ctgacgatag atagtcaaac
    64141 cgccttcgtc ttctgagtgt tcttcaatca attccaactt gtaagggtca tttttgaaga
    64201 tttcacgtgc ctcgtcttta gtcacttctt cacgaataga tgggaagttt tctttgacga
    64261 ttttttgcat ttcttcttcg atacgaggaa ggtcttcgtt agagatttga ccagctgtgt
    64321 tgtcagtatc gtagtagaaa ccatcttcga tggctggacc aactcccaag tgaatgtctg
    64381 ggaaaagacg acgagctgct tgggcgaaca agtgagctgc tgagtgacgc aagattggaa
    64441 gggcatcttc gtgatcaggt gtcacaattt cgatgcttcc atcttcagtg atagcgcgag
    64501 tagtgtcgat gagtttgccg ttgaatttac cagccaaggc ttttttagct agggaattgc
    64561 tgatagattg ggcaatttca aaagttgtta cgccagattc gaattcacga acagcgccat
    64621 ctgggaaagt aatgttaatc atgatgttct ccttttttat tatttcatag tttctaagca
    64681 ttgatttttt atcagcagac tacttccgag tcctaacgtt caattgcttt tctttatcag
    64741 agaggaagtt tttcatttcc gtcagaatgt ctatatccaa acgttgagaa agttctaata
    64801 gccaccagat attttctgaa agtttttgtt ccagtgtgta gggtgtttca tcatagtagc
    64861 gtccttgctt tgtcatcacc agtcattgga aatttccaat atcattagat aaagccaaga
    64921 ggtcttcttc taccgtccac ttgaaatcat gatgcttaac ttccagttcg tgataagctt
    64981 gtcggattgc ccaactgcgc tccactaatt cttgcaactc cataattagt atcctaataa
    65041 aaaaatgcga catcctcgaa aggacgtcgc aacgtggttc caccttcatt tatgtacctc
    65101 aaaagagagg gacacctctg atcggctcta acgtggccac cgttttatgt tttcataaaa
    65161 aactcaagag tagtatcagt ttagacttcc tatgcgtttc cagcaaccac gcactctcta
    65221 gtagaaaggg actaagtgac ttgtctctat ggattattat agcatgattg tgagattttt
    65281 caaggatttt gtgaaagttt tttgtttttc attttttgta gaatatgctt gatgctaata
    65341 ccagaatcca tgccgaccag agcaactgtt tcatagatta gcaagtaaat tagtataaac
    65401 tcaccaaagg ttatgatagt aaagtaaaag agcagtccgt taccaactaa ccatcaaagt
    65461 gagaaacgga aacggtagct atagagtaac gatataatca agattaccag aggtgtaaag
    65521 aagagaagat tgtttatata gagttccttg agtgtaaggg ggtcagaaac aactagtaag
    65581 aacaactcat aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa
    65641 tagaatctac gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct
    65701 atgattatta tagcatgttt aaaacaagaa agtaaatttg ttgacaaaga agatttttct
    65761 tttcactaga atcatagtta gttttcttgg tagaaatatt ttgataataa ttaagcaaga
    65821 ctattgacat taattattaa gagtgtcaca attgttgtaa ctaaaataat tacaacaaga
    65881 gaggtataaa aaatgaaact agcagttatt gcagcaaatg gacaagcggg gaaagcaatt
    65941 gttgaagaag cagtcaaacg aggacatgaa gtaacggcta ttgttcgttc tgaaaacaaa
    66001 agtcaagctg agtctattat taaaaaagat ttatttgagt tgacaaaaga tgatcttact
    66061 ggatttgatg ctgttatttc agcgtttggt gcttatacac cagatacgct accgctccac
    66121 agcaaatcaa tcgaactatt taatcagctt cttgctggaa cacagacacg ttttctagtt
    66181 gtagggggag caggaagtct ttatatagat gaaacaaaaa cgacacgact tttagatacg
    66241 tctgattttc ctgaagaatt taagtcacta gcaaaagctc aagcggatga attggatctt
    66301 cttcgtacaa aaaataatct caactggact tttgtcagtc ctgctgtaga ttttattccc
    66361 gatggtgaaa aaacaggaaa ctacattcta gcaggagaaa tttttactac taatggaaaa
    66421 ggaataagcc agattagtta tgcagattat gctattggat tggtagatga acttgaaaaa
    66481 ggtcatcata taaaagaacg tatctcttta cttgaaaaat aataactatg agagtattaa
    66541 tgtttgacag aaaatttaaa tcttggtaaa ataaggattg tcgtaaagac aaataacttc
    66601 ttcttggtta caggcatgcc aacctgtcac tcggatgaag ccaaataaaa aggagaaaca
    66661 tcatggcaat ctcaaaagag aaaaaaaatg aaatcattgc acaatatgca cgtcacgaag
    66721 gtgatacagg ttcagtagag gttcaagttg ctgtccttac ttgggaaatc aatcacctta
    66781 acgaacacat caaacaacat aaaaaagacc acgctactta ccgtggattg atgaaaaaaa
    66841 tcggtcgccg tcgtaacttg cttgcatact tgcgtaaaaa cgacgttaac cgttaccgtg
    66901 agttgatcaa ctctctagga cttcgtcgct aattcaagat acaaatgctg tcaaaagcac
    66961 aaagcaaaaa taggaaaatt gacgaagaaa cttcagtttc taggagattt tatctttttt
    67021 gccaagtgct taggccgtgt tcaattgagc atatcttgat aataaagcta ctctaaattg
    67081 ggtagctttt ttgcgttgtc accttacctc gatatactca agtataatct ttggttacgg
    67141 ttcctagcac tgtaaggtaa aataaaccag cttttctccc ttcggggaga tttttttgtt
    67201 tcactgaaag tttcgtacga tcttcgcctc gtcgcctagt ctataaacga tttatctagc
    67261 aagaatcatg atgctaaggg cgtcaaaaat ccgtatgaaa atagggaaat gacacagtgt
    67321 tcgatgagca caaggagttt catctttttc actaggattt tagcccgggc tcaaatcagc
    67381 tctctgactt cagagggctt ttttattgag gttttatcgg taacaatttt ggagactaca
    67441 aaaatctcaa acggtatcag ctaattacac cataaaggtg cgcagttact cggcttttca
    67501 agccgagtag ctgtatgcaa gccccctaga agagcccact ctttacaaag taaagtatag
    67561 tatgttatac tttacatgga agtagtcact gaattccagt tagaaattac tttgtaacta
    67621 cgttttgagg aggagtaaaa tgctttccta cgttcgacat tacccactag cgatagctaa
    67681 attaatgtgt ctgtgctctc ctaaaatctg ctgatttatt actgactaat acaggagttt
    67741 tttttatggg acagacaatc atatctgcta ttggtgttta tatttccacc agtatcgatt
    67801 atttaattat tttaattatt ttatttgcac agctatcaca gaataaacag aaatggcata
    67861 tttatgcggg gcaatatcta ggcacaggct tacttgtagg ggcgagttta gttgctgctt
    67921 atgtcgttaa tttcgtgcct gaagaatgga tggttggatt gcttggttta atccctatct
    67981 atttagggat tcgctttgca attgttggag aagatgcgga agaagaagag gaagaaatta
    68041 ttgaaagatt agaacaaagc aaggcaaatc aactgttttg gacagttaca ttgctgacaa
    68101 ttgcgtctgg cggagataat ttaggtatct atatacctta ttttgcttcg ttagattggt
    68161 cacagaccct cgtggccttg cttgtgtttg taatcggcat aattatcttt tgcgagatta
    68221 gtcgggtgtt atcctctatt ccgttaatat tcgagacaat tgaaaaatac gagcgaatca
    68281 ttgtgccctt agtattcatt ctacttggac tatacatcat gtatgaaaat ggcacgatag
    68341 agacttttct gatcgtgtag atttttttgt ttcactagga ttttagtccg agctcaaatc
    68401 agctctctga ttttcagagg gctttttcat tgagtataaa tggacaatct taaagttact
    68461 ctattgtaga gtggcttttg atttgattag gagattctta taaatatagt aaaatgaaat
    68521 aagaatagga caaatcgatc aggacagtca aatcgatttc taaaaatgtt ttagaagtag
    68581 aggtgtacta ttctagttcc aatctactat ataaatgaaa accttagctg tttcgccaag
    68641 gttcatttct tctatgcaag ttcttctctt ttcttatctg ggttccagat gaagcttgcg
    68701 ataaagctaa agatgatggt taggatagcg aggataatag caaggatgag ggcagggatg
    68761 cggataaacc accagagtgg atttggtttt ttatcattgt gccattgttt cgtttcttcg
    68821 tccagacgtt ggaattctgt ttgaatacga ttggcgactg tttcaatgcc ttcatcattc
    68881 attttcttga tatctgagat atcgattgga tttccaaagt tcatatcgac acgttcacgg
    68941 ctaatcaagc ccttcaaagt catgggaccg gtgtaggtaa ccggcatgat acggaccttg
    69001 gccattttgg caatcagtgc tgcgcccccc ttgacatcgt ttgagtggcg gctaccactt
    69061 ggaaacatga tgagagagcg gtcacttttt ttgagaacgt tgataggata tttgatggct
    69121 gaggcgctgg gattttcacg gtcgatggga aaggcgccac acatacgaat ccaccaacca
    69181 aagatacggt tggtaaagag ttcttttttt gccataaaga tgaactgttt tggcttggtc
    69241 gcaaaggcca tataaacagg atcccaccag gtacggtgag gcgcaactaa aatataattt
    69301 tcatcttgat taggaatttt attagtatta tgatagtgag cattgccatt gatggaccat
    69361 aagagcaata caactaatcc acgcaaataa gtataaaaca tgcgatctcc ttcgattgtt
    69421 ttcttgttat tattatacct tatcaaagga gggctggcaa acttttccct tgactagatg
    69481 catatttggg atgaaattag aattctgtta aaaaaaatga tataatagaa tttatggata
    69541 aaaataagat tatgggatta acccaaagag aagtcaagga aagacaggct gagggtttgg
    69601 tcaatgactt taccgcatca gccagtacca gcacttggca aatcgttaaa cgaaatgtct
    69661 ttaccctttt taacgctttg aactttgcca ttgctttggc tcttgccttt gtgcaggctt
    69721 ggagcaatct ggtcttcttt gctgttatct gctttaacgc tttttctggg attgtgaccg
    69781 agctacgagc caaacacatg gtggacaagc tcaatctcat gaccaaggaa aaggtcaaaa
    69841 ccatccgtga tggtcaggaa gttgctctta atcctgaaga attagtgcta ggagatgtca
    69901 ttcgtttgtc tgcaggagag cagattccta gtgatgcctt ggttttggaa ggctttgcgg
    69961 aagtcaatga agccatgtta acgggagaaa gtgatttggt gcaaaaggaa gttgacggct
    70021 tacttttgtc aggaagtttc ctagccagtg ggtcagtttt atctcaagtt caccatgtcg
    70081 gtgcagacaa ctatgctgcc aaactcatgc ttgaggctaa gaccgttaaa cccatcaact
    70141 cccgtatcat gaaatcgctg gacaagttgg ctggttttac tgggaagatt atcattccct
    70201 ttggtctggc tctcttgctg gaagccttgc ttttaaaagg cctgcctctc aagtcatccg
    70261 ttgtaaactc gtcgacagct cttttgggaa tgttgcctaa gggaattgcc cttttgacca
    70321 ttacttcgct cttgactgca gtgattaagt tgggcttgaa aaaggtcttg gtgcaggaga
    70381 tgtactctgt tgagaccttg gcgcgcgtgg atatgctctg tctggacaag acgggcacca
    70441 tcacccaagg aaagatgcag gtggaggctg ttcttccact gacggaaact tacggtgaag
    70501 aggctattgc cagcatcttg actagctaca tggcccatag tgaggataag aatccaactg
    70561 cccaagccat tcgccagcgt tttgtgggag atgttgctta tcctatgatt tccaatcttc
    70621 ccttctcgag cgaccgcaag tggggggcta tggagttaga aggcttgggg acagttttct
    70681 taggggcacc tgagatgttg ctggattctg aagtcccaga agccagggag gccttggaga
    70741 gaggatcacg tgtcttggtc ttagctctca gtcaggagaa attagaccat cacaaaccac
    70801 agaaaccatc tgatattcag gctctagcct tgctggaaat cttggacccc attcgagagg
    70861 gagcagcaga gacgctggac tatctccgtt ctcaggaggt gggactcaag attatctctg
    70921 gtgacaatcc agttacggtg tccagcattg cccagaaggc tggttttgcg gactatcaca
    70981 gctatgtaga ttgctcaaaa atcaccgatg aggaattgat ggccatggcg gaggagacag
    71041 ctattttcgg acgtgtttcc cctcatcaaa agaaactcat catccaaacg ttgaaaaaag
    71101 cgggtcatac aacggctatg acaggggacg gggttaatga tatcttggcc cttcgtgagg
    71161 cggattgttc tatcgtgatg gcggaggggg atccagcaac ccgtcagatt gccaatctgg
    71221 ttctcttgaa ctcagacttt aatgatgttc ctgagattct cttcgagggt cgtcgcgtgg
    71281 tcaataacat tgcccacatc gccccgattt tcttgataaa gaccatctat tccttcctgt
    71341 tagcagtcat ctgtattgcc agtgctttac taggtcggtc agagtggatt ttgattttcc
    71401 ccttcattcc gatccagatt accatgattg accagtttgt ggaaggtttc ccaccattcg
    71461 ttctgacttt tgagcgaaat atcaaacctg tcgagccaaa cttcctcaga agatccatgc
    71521 ttcgtgccct accaagtgcc ctcatggtcg tgtttggcgt tctttttgtg aaaatctttg
    71581 gaacgagtca aggttggtct gagttagaaa tctcaactct cctctattat ctcttggggt
    71641 caattggttt cttatccgta tttagagcct gcatgccatt cactctatgg cgagtcctat
    71701 tgattgtctg gtcagtagga ggcttcctag ccacagctct cttctcaaga attcaaaaac
    71761 tgcttgaaat tgcaacctta acaggacaaa cattacctgt ttatggtgtc atgatgttgg
    71821 tctttaccgt gattttcatc ctgaccagtc gttaccaagc gaaaaaataa agaaagactg
    71881 caatctgtgg attgcagttt ttttaggtac aagattgcca gccgaaatgt ggtataataa
    71941 gaggtaatag agttttggaa agtgagagaa gatgatttca aagagattag aattggtagc
    72001 ttcctttgtg tcacaggggg ctattttact agatgtggga agtgaccatg cttatctgcc
    72061 tatcgagttg gttgagagag gccaaatcaa aagcgctatt gcaggtgagg tggtggaagg
    72121 tccctatcag tctgcggtta aaaatgttga ggctcacggc ctaaaggaga aaatccaagt
    72181 ccgtttagcc aatggcttgg cagcttttga agagactgac caagtgtctg tcattaccat
    72241 tgctggcatg ggtggttgtt tgattgctag gattttagaa gaaggtttgg ggaagttagc
    72301 taatgtagag cgtttgatcc tccagcccaa taatcgtgaa gacgacttgc gtatctggct
    72361 acagaatcat ggattccaga ttgtagcaga aagcatctta gaagaagctg gcaagtttta
    72421 cgagattttg gtggtggaag caggacaaat gaagctatca gccagtgatg ttcgctttgg
    72481 tcccttcttg tccaaagaag tcagtccagt atttgtccaa aaatggcaaa aagaagctga
    72541 gaagctagag tttgccctcg gacaaatccc agaaaaaaat ctggaggaac gtcaagttct
    72601 agtagataag attcaagcta tcaaggaggt gctccatgtt agcaagtgaa gtgatccaag
    72661 cttatgaagc cttttgccct caggaatttt ctatggaggg agacagccgt ggtctgcaaa
    72721 ttggcacttt agacaagggt atccaaaggg tcatggttgc cctcgatatt cgtgaagaga
    72781 cggtggcaga ggccattgaa aagggtgtgg acttgattat cgtcaagcac gcgcctatct
    72841 ttcgtcctat caaggacttg cttgccagcc gtccgcaaaa tcagatttac atcgacctga
    72901 ttaagcatga catcgcagtt tatgtcagcc ataccaatat tgatatcgtt gaaaatgggc
    72961 tcaatgactg gttttgtcag atgctaggaa tcgaggagac gacttatctg caggaaacag
    73021 gtccagaacg tggaattgga cgtattggga atattcagcc tcagacattt tgggaattgg
    73081 cccaacaggt caagcaagtc tttgacctag atagccttcg aatggtgcat tatcaagaga
    73141 atgatttgca gaagcctatt tcaagagtag caatttgtgg tggaagcggg cagtctttct
    73201 ataaggatgc tttggcaaag ggggcagatg tctatatcac tggtgatatc tactaccata
    73261 ctgctcagga tatgctgtct gatggcttgt tagcattgga tccaggtcac tatatcgaag
    73321 tgctttttgt ggaaaaaatc gcagcactcc ttactcaatg gaaagagaaa aaaggctggg
    73381 aactagagat tttacctagt caagcatcga ccaatccttt ccgtcatatc tagttagaaa
    73441 gtgaagacaa tgaaaaaagt tgccattatt ggagcaggaa ttgtgggagc aacagctgcc
    73501 tactacctct cgagagaaag tgacctagag gtgaccgttt ttgaccatga gcaaggtcaa
    73561 gccaccaagg ccgcagcagg aattatcagt ccttggtttt ccaaacgccg taataaagcc
    73621 tggtacaaga tggcgcgctt gggggctgac ttttatgtgg atttattagc tgatttagag
    73681 aaatcaggac aaaaaatcga cttttaccag cgttcgggag tctttctctt gaaaaaggat
    73741 gaatccaagt tggaagaact ttatcaactg gccctccagc gcagagaaga atctcccttg
    73801 atagggcaat tagccattct ggaccaagct tcagctaatg aattattccc tggtttgcag
    73861 ggatttgacc gcctgctcta tgcttctggt ggagcgagag tagatggcca actcttggta
    73921 actcgtctgc tagaagccag tcatgtcaag ctggtcaaag aaaaagtgac tctgacactc
    73981 ttatcatcag gctaccagat tggcgaagag gtgtttgatc aggttatttt ggcaacggga
    74041 gcttggttgg gggacatgtt agagccttta ggttatgaag tggatgtccg tcctcaaaaa
    74101 ggacaactac gagattatca gcttgcccaa gacatggaag attaccctgt tgtcatgcca
    74161 gaaggggagt gggatttgat tccctttgca ggtgggaaat tatccttggg cgctacccat
    74221 gaaaatgaca tgggatttga tttgacggta gatgaaccct tgctccaaca aatggaggag
    74281 gcggccttgc ctcattaccc agttttagct agagcgactt caagggctga gcgtgtggga
    74341 atccgtgcct ataccagtga tttctctccc ttctttgggc aggtgccaga attggcaggt
    74401 gtctatgtag ccagtggact aggttcatca ggcctcacaa ctggtcctat cattggttac
    74461 catctagccc aactgatcca agacaaggag ttgaccttgg accctctaaa ttatccaatt
    74521 gaaaactatg tcaaacgagt aaaaagcgaa taatactcaa tgaaaatcaa agaacaaact
    74581 aggaaactag ccgcgggtta ctcaaagcac tgctttgagg ttgtgtatag aactgacgaa
    74641 gtcagtaacc atacccatgg caaggcgacg ttgacgtggt ttgaattgga ttttcgaaga
    74701 gtataagcat tttactgaaa ttttatcagg tagtttagga tggcaaatga cattccctgt
    74761 caaaaatggt aaaataagaa aaaataatct gagaatcgag gaaaaaagat gcaagaaaag
    74821 attttggtaa ctggtggtgc cggttttatt ggaacccaca ctgttattga attgatccaa
    74881 gcaggccatc aagttgttgt ggtggataat cttgtcaata gcaatcgtaa gagtttagaa
    74941 gttgttgaaa gaatcacagg agttgagatt cctttctatg aggcagatat tcgtgacaca
    75001 gttaccctca gagatatttt caagcaggaa gaaccgactg gtgtcattca ctttgctggt
    75061 ttgaaggctg ttggcgaatc aacacgtatc cctcttgcct actatgacaa caatatcgct
    75121 ggaactgtca gccttttgaa agccatggaa gaaaacaact gtaaaaacat catcttcagt
    75181 tcttctgcga cagtttacgg ggatccgcac acagtgccca tcttggaaga tttcccactt
    75241 tcagtgacca acccatacgg tcgtaccaag ctcatgctag aggaaatttt gaccgatatt
    75301 tacaaagcag actcagaatg gaatgttgtc ttgcttcgtt actttaaccc aatcggagcc
    75361 catgagagtg gtgatttggg agaaaatcca aacggtattc caaacaatct cttgccatat
    75421 gtgactcaag tagccgttgg aaaattagag caagtgcaag tgtttggaga cgattacgat
    75481 acggaagatg gaacaggtgt tcgtgactat atccacgttg tcgatttggc taagggtcac
    75541 gttgcagctt tgaaaaaaat ccaaaaaggt tcaggactaa acgtttataa ccttggaact
    75601 ggtaaaggtt actcagttct tgaaattatc caaaacatgg aaaaagcggt gggacgtcct
    75661 attccttacc gcatcgtaga acgtcgccca ggtgatatcg ctgcctgcta ctcagaccca
    75721 gcaaaagcta aagcagaact cggttgggaa gcagaactcg acatcaccca aatgtgtgaa
    75781 gacgcatggc gttggcaaag caagcatcca aatggatttg aagactaaga tgatgatttc
    75841 aatcatcgtc ccttgtttaa acgaagagga agtacttcct cttttttatc aggctctgga
    75901 agctttactt ccagatttgg aaacagaaat cgagtatgtc tttgtcgatg atggatcaag
    75961 tgatgggacc ttggaactct taaaggccta tcgggagcaa aatccggcag tccattatat
    76021 ttctttctct cgaaattttg gcaaagaagc agccctttat gcaggcttgc aatatgcgac
    76081 aggagatttg gtggtggtga tggatgcaga cctccaagat cctcctagta tgttgtttga
    76141 gatgaaaaat gtactagaca aaaatgtaga cttggactgc gttgggacac ggagaactag
    76201 tcgggaggga gaacccttct ttcgcagttt ctgtgctgtt ctcttttatc gcctcatgca
    76261 aaaaatcagc ccagtagctc tgccgtcggg tgtccgtgac tttcgtatga tgagaaggtc
    76321 tgtggtcgat gccattttaa gcttgactga gtccaatcgt ttttctaagg gactctttgc
    76381 ctgggtcggc tttaaaaccc actatctgga ctatccaaat gtcgaaaggc aggctggcaa
    76441 gaccagttgg agttttaggc aactcttttt ttactccatt gaagggattg ttaatttttc
    76501 agatttccct ttgactatag cctttgtagc tggtctccta tcttgttttc tttctctgct
    76561 gatgaccttt tttgttgtgg ttcggaccct cattttgggc aatccgacat ctggttggac
    76621 ctctctgatg gctgttattc tctttcttgg aggcattcaa ctcttgacca ttgggattct
    76681 cggtaagtat atcagtaaga tttatttaga gactaaaaaa agaccacttt atcttatcaa
    76741 agaaaaaagt gaccttcctg attttacaga aaaaaataaa gtgaaaagac tataatttta
    76801 catggaaatg tgctaaacta gagggagtgg attatcgcca ttgatttagg cttcctggtt
    76861 tccaatcagg gcgcgagttg ggcaattttt aacagcctct aagacatcct gactaggaga
    76921 aatttctttt tccagttggt cagggtcatc gtaaaaacgc acgattccat tatcgtggta
    76981 atcaaataaa tcagaataag tttggcaaag tccacaggcg atacatcgtt caggtataag
    77041 tgtgattttc atgttcatat ttatattgta ataagaaaag taaaaaaaaa caaggagtaa
    77101 ggtatggcaa aagaaccgtg gcaagaagat atttatgatc aagaagaatc aagagcaggg
    77161 cgtcggcatc gaaaccacgg aggggctgat aggatggcta atcgtatttt gacgatccta
    77221 gctagtattt tctttgtaat tgtggtggtg atggtcatcg ttctcatcta tctatcatcg
    77281 ggggggagta atcgcacagc agccttaaaa gactttcatg attctgatgc aagtgtagta
    77341 caaatctcat cttcaagcag ttctcagcct gagcagagtt cagagccaga atctacttct
    77401 agtagttcag aagaagctgc taatcctgaa ggaacgatta aagttctcgc aggagaaggg
    77461 gaagcagcta ttgccgctcg tgcaggaatc tccattgctc agttagaggc cttgaatcct
    77521 gggcacatgg ctacaggatc ttggtttgct aatccaggtg atgttataaa aataaaatag
    77581 gagccgatat gaaaacaatt caaattgcta ttgatggtcc tgcttccagc ggtaagagta
    77641 cggtcgcaaa gattattgct aaggattttg gattcaccta ccttgataca ggagctatgt
    77701 atcgtgcagc gacctatatg gctcttaaga accaattagg agttgaagaa gtcgaagccc
    77761 ttctagcctt gttggaccag catccaatca gctttggacg ttcagaaact ggagaccagc
    77821 ttgtttttgt aggagatgtg gatattaccc atcctatccg tgaaaatgaa gtgaccaatc
    77881 atgtttctgc tattgcagca attcctgaag tgcgtgagaa actggtttct ctccaacaag
    77941 aaattgccca gcaaggcggg attgtcatgg atggtcgcga tattggaact gttgtattgc
    78001 cacaagcaga attgaaaatt ttcctagtag cttctgttga tgagagagca gagcgtcgtt
    78061 acaaggaaaa tattgccaag ggaattgaaa cagaccttga aaccctaaaa aaggaaattg
    78121 ctgcgcgtga ctacaaggat agtcatcgtg agacttctcc tctcaaacaa gcagaggatg
    78181 ctgtctacct tgatacaact ggtttgaaca ttcaagaagt agttgaaaaa atcaaagcag
    78241 aagctgaaaa aagaatgtaa atgtagaaaa gccgatagat tgatatcggt ttttttctaa
    78301 atttgtcaaa atgctgattt tagggtataa tagttgctgt tcgagaaatt ttgattttca
    78361 aagaatagtg aatgatgata aggagaaacc atgaacaatt taccaaattg tccaaaatgt
    78421 aactcagagt atgtctacga agacggtgcc ctactggttt gcccagagtg tgctcatgag
    78481 tggaatcctg ctgaagttgc agaagtagaa gaaggtcttg tcgctatcga tgccaacgga
    78541 aataaattgg ctgatggtga tatagtaact ctcatcaagg acttgaaagt aaaaggtgcg
    78601 ccaaaagatt tgaaacaagg gacgcgcgtg aaaaatatcc gcatcgtaga aggcgaccac
    78661 aatatcgact gtaagattga tggttttggt gccatgaaac ttaaatcaga gtttgtgagg
    78721 aagatttaag catgtcaaaa cactataaac ttgtatttta tagccgtatc ttcttgtttc
    78781 tagcggcttt tacgggagtt tatcttgaaa ttactaggca tggtggtttt gggatgcttc
    78841 tctattacac ggttctgtcc aacctcttgg taactatttt taccctttat cttctaaagg
    78901 ttatgagccg tgtaggtgaa aattggcaaa ggccaagtct cttgcgctta aaaggtgggg
    78961 tcaccatgag tatcatgatt acctgtgtga tttaccattt cctcttggcg cccattgcga
    79021 ctaatttcta taccctagaa aatttccttt gccactatat cgttcccatc tggtttttag
    79081 cggataccct cttttttgac aaacagggtc aatacaagat ttgggatcca gcagtgtgga
    79141 ccattttacc ctttctgtat atgatgtttg ctctttttaa tggcttggtt ctaaaactca
    79201 atattccaaa tgccaaggat aatcctttcc cttacttctt tttgaatgtg aacaagggtt
    79261 ggaatgttgt gtttaagtgg tgtctgatta tctttgttgc ctatatggta gcaggattta
    79321 ttttctactt tatcaagcaa atcaagagaa agtcatccta atactcttcg aaaatctctt
    79381 caaaccacgt cagtttccat ctgcaacctc aaaacactgt tttgaacaac ctgcggctag
    79441 cttcctagtt tgctctttga ttttcattga gtataagata caagggattc attttcgaat
    79501 ttaagaagga gtctacaaac caatgaggct tcttcttttc ttgcttattt gataactatc
    79561 aaaaaagtag aagattaaga gaaatataga aagagatttc atgaaacaat ttttagaacg
    79621 ggccagcatt ttggctctct ccctcgtttt gattacctcc ttttccattt cgagtgccct
    79681 accagccatg tttgactatt atcagggtta ttctaaggaa caaattgagc tcttggtgag
    79741 cttgccttcc tttggaatca tgatgatgtt actgctaaat ggtttcttag aaaaaatatt
    79801 tcctgagcgc ttacagatta gtttgggctt gctgatttta tcattgagcg gtacagctcc
    79861 cttctggtac caagcctatc cctttgtctt tggaacacgg cttctctttg gtttgggtct
    79921 tgggatgatc aatgccaagg ccatttctat tatcagtgaa cgctatcaag gaaaaaggcg
    79981 aattcagatg ttagggctac gcgcttctgc agaggtcgtt ggagcttctc tcattacctt
    80041 ggccgtcggt cagttgttgg cctttggttg gacagctatc tttctagcct atagtgctgg
    80101 atttttggtg ctgccccttt atctgctctt tgtcccttat ggaaaatcaa agaaagaagt
    80161 caagaaaaga gcgaagaaag caagtcgttt aactcgagaa atgaaaggct tgatttttac
    80221 cttagctatc gaagcggcag ttgtagtttg taccaataca gctattacca tccgtattcc
    80281 aagtttgatg gtggaaagag gattggggga tgcccagtta tctagttttg ttcttagtat
    80341 catgcagttg atcgggattg tggctggggt gagtttttct ttcttgattt ctatctttaa
    80401 agagaaactg ctcctctggt ctggtattac ctttggcttg gggcaaatcg tgattgcctt
    80461 gtcttcatcc ttgtgggtgg tagtagcagg aagtgttctg gctggatttg cctatagtgt
    80521 agtcttgacg acggtctttc aacttgtctc tgaacgaatt ccagctaaac tcctcaatca
    80581 agcaacttca tttgctgtat taggctgtag tttcggagcc tttacgaccc catttgttct
    80641 aggtgcaatt ggcttactaa ctcacaatgg gatgttggtc tttagtatct taggaggttg
    80701 gttgattgta atctctatct ttgtcatgta cctacttcag aagagagctt aggattgatt
    80761 cctaagtttt tcttttgata ctcaatgaaa atcaaagagc gtagttgatt gagtttggaa
    80821 tagtacgctg tagctgctaa aatatttcta gaaattaatt tgactttcct aatagagttg
    80881 ttcatatctt atttcaatct actatagaaa gctagccgca ggttgctcaa aatagtgttt
    80941 tgaggttgca gatggaaact gacgtagttt gaagagattt tcgaagagta tgagattttt
    81001 atacccatac aatatttgtt ttaggtcctt gtttacagac taatttcttg ataaaataga
    81061 ggttatgacg agatataaag caactatttc ctatgatggt tatgcctttg ctggctttca
    81121 gcgccagcct catgcgcgta gcgttcagga agaaattgaa aaaaccttga ccagattaaa
    81181 taaagggcaa accattactg ttcacggtgc tggtaggaca gatagtgggg ttcatgccct
    81241 gggacaggtc attcattttg acctgcctta tcagatggat gaggagaaac tccgttttgc
    81301 cttggatacc cagtctcctg aagatattga tgtgatttcg attgagcttg tggcagatga
    81361 ttttcattgc cgttatgcca aacatagcaa gacctatgag tttattgtgg atagaggacg
    81421 tcccaaaaat cctatgcgcc gtcactatgc cacccacttt ccctacccac tcgatgtgga
    81481 acgaatgcag attgcaatca aaaagctaga gggaacccat gattttaccg gttttacagc
    81541 ctctgggact agtgtagagg ataaggttcg caccatcaca gaagctagtt taatagtcga
    81601 tgagacagga caatttttga cctttacctt ttcaggaaat ggtttcttgt ataaacagat
    81661 tcgcaatatg gtggggactc ttctcaaaat cggtaacaac cgcatgccag tagagcagat
    81721 tgctctcatc ttggagaaga aggacaggca acttgcaggt cccactgcag caccaaatgg
    81781 tttgtattta aaggagattc gttatgaaga ataatcgtat tttagcactt tctggaaatg
    81841 atatttttag tggtggtgga ctgtcagctg atttggctac ctataccttg aacggcttgc
    81901 atgggtttgt agcagtgact tgtttgacag ccttgacaga aaaaggattt gaagtctttc
    81961 caactgatga taccattttt caacatgaat tagatagctt gcgtgatgtg gaatttgggg
    82021 gaattaagat tggtcttctc cctactgtca gtgtggctga gaaggccttg gactttatca
    82081 aacaacgccc aggagtacct gtggtgttgg atcctgtctt ggtctgcaag gaaacgcatg
    82141 atgtagctgt cagtgagctc tgccaagagt tgattcgctt cttcccttat gtcagtgtga
    82201 ttacgcctaa tctcccagaa gcagaattat tatccggtca ggaaattaaa accttggaag
    82261 acatgaaaac tgcagcgcag aaattgcatg atttaggagc gccagcagtc attatcaagg
    82321 gaggcaatcg tcttagtcag gacaaggctg tggatgtctt ttatgatgga cagaccttta
    82381 ctatcctaga aaatccagtt atccaaggcc aaaatgctgg tgcaggttgt acctttgcct
    82441 ctagcattgc cagtcacctg gttaaaggtg ataaactttt gccagcagta gaaagctcta
    82501 aggctttcgt ttatcgtgct attgcacaag cagatcagta tggagtaaga caatatgaag
    82561 caaacaaaaa caactaaaat cgcccttgta tccctattaa ccgccctttc tgtggttcta
    82621 ggttatttct taaaattccc aacacctaca ggaattctaa ctcttttaga tgctggtgtc
    82681 ttctttgcgg ccttttactt tggtagtcgt gaaggagcgg tagtcggagg actagcaagt
    82741 ttcttgattg acctcttatc aggctaccct cagtggatgt tctttagctt ggtcaaccat
    82801 ggcttgcagg gatttttcgc aggatttaaa ggaaaaagtc agtggttagg ccttatttta
    82861 gcaactattg ccatggtagg aggctacgcc ttgggttcta ctttgatgaa tggctgggca
    82921 gcagccctcc cagaaattct accgaatttt atgcaaaata tggtagggat gattgtagga
    82981 tttattctta gtcaaagtat caagaagatt aagtaatact cttcgaaaat ctcttcaaac
    83041 cacgtcagct tccatctgca acctcaaaac actgttttga gcagcctgag gctagctttc
    83101 tagtttgcac tttgattttc attgagtata aagaggttga gtaaaaagtc tttcaaataa
    83161 gaaaaacgca ttatatcaag tcttgactga actg
//
LOCUS       DBEROT010000005        67267 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.05, whole genome shotgun sequence.
ACCESSION   DBEROT010000005 DBEROT010000000
VERSION     DBEROT010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 67267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.05"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..772)
                     /locus_tag="ACL8CG_000385"
                     /pseudo
     CDS             complement(1..772)
                     /locus_tag="ACL8CG_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1258..1656)
                     /locus_tag="ACL8CG_000386"
     CDS             complement(1258..1656)
                     /locus_tag="ACL8CG_000386"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343048.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            1784..2017
                     /locus_tag="ACL8CG_000387"
     CDS             1784..2017
                     /locus_tag="ACL8CG_000387"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343049.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVVDRTDEVS
                     SKHGFEVVDETDEVSNHIYGKATLTWFEEIFEE"
     gene            complement(2074..2556)
                     /gene="greA"
                     /locus_tag="ACL8CG_000388"
     CDS             complement(2074..2556)
                     /gene="greA"
                     /locus_tag="ACL8CG_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGS1343050.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(2627..4282)
                     /gene="mltG"
                     /locus_tag="ACL8CG_000389"
     CDS             complement(2627..4282)
                     /gene="mltG"
                     /locus_tag="ACL8CG_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGS1343051.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVSTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(4363..4857)
                     /locus_tag="ACL8CG_000390"
     CDS             complement(4363..4857)
                     /locus_tag="ACL8CG_000390"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343052.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(4854..5318)
                     /locus_tag="ACL8CG_000391"
     CDS             complement(4854..5318)
                     /locus_tag="ACL8CG_000391"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343053.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(5328..6662)
                     /gene="murC"
                     /locus_tag="ACL8CG_000392"
     CDS             complement(5328..6662)
                     /gene="murC"
                     /locus_tag="ACL8CG_000392"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGS1343054.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(6673..7290)
                     /locus_tag="ACL8CG_000393"
     CDS             complement(6673..7290)
                     /locus_tag="ACL8CG_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS1343055.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(7338..10436)
                     /locus_tag="ACL8CG_000394"
     CDS             complement(7338..10436)
                     /locus_tag="ACL8CG_000394"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1343056.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINRQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADTNLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADSHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(10529..11695)
                     /locus_tag="ACL8CG_000395"
     CDS             complement(10529..11695)
                     /locus_tag="ACL8CG_000395"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGS1343057.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNESKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(11703..12797)
                     /locus_tag="ACL8CG_000396"
     CDS             complement(11703..12797)
                     /locus_tag="ACL8CG_000396"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS1343058.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVFAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(12955..13677)
                     /locus_tag="ACL8CG_000397"
     CDS             complement(12955..13677)
                     /locus_tag="ACL8CG_000397"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343059.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLEQFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDESTANLDAYSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEERKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            complement(13702..14637)
                     /locus_tag="ACL8CG_000398"
     CDS             complement(13702..14637)
                     /locus_tag="ACL8CG_000398"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343060.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            complement(14809..16767)
                     /locus_tag="ACL8CG_000399"
     CDS             complement(14809..16767)
                     /locus_tag="ACL8CG_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1343061.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDANNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIHSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(16971..18593)
                     /locus_tag="ACL8CG_000400"
     CDS             complement(16971..18593)
                     /locus_tag="ACL8CG_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGS1343062.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            18699..20144
                     /locus_tag="ACL8CG_000401"
     CDS             18699..20144
                     /locus_tag="ACL8CG_000401"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGS1343063.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGNIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMVIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(20187..20384)
                     /locus_tag="ACL8CG_000402"
     CDS             complement(20187..20384)
                     /locus_tag="ACL8CG_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS1343064.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(20485..21056)
                     /locus_tag="ACL8CG_000403"
                     /pseudo
     CDS             complement(20485..21056)
                     /locus_tag="ACL8CG_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(21040..21552)
                     /locus_tag="ACL8CG_000404"
     CDS             complement(21040..21552)
                     /locus_tag="ACL8CG_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGS1343065.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLRDSDF"
     gene            complement(21638..22573)
                     /locus_tag="ACL8CG_000405"
     CDS             complement(21638..22573)
                     /locus_tag="ACL8CG_000405"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGS1343066.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(22644..22943)
                     /locus_tag="ACL8CG_000406"
     CDS             complement(22644..22943)
                     /locus_tag="ACL8CG_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGS1343067.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(22933..23682)
                     /locus_tag="ACL8CG_000407"
     CDS             complement(22933..23682)
                     /locus_tag="ACL8CG_000407"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGS1343068.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(23736..24095)
                     /locus_tag="ACL8CG_000408"
     CDS             complement(23736..24095)
                     /locus_tag="ACL8CG_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGS1343069.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(24097..25497)
                     /locus_tag="ACL8CG_000409"
     CDS             complement(24097..25497)
                     /locus_tag="ACL8CG_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGS1343070.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(25792..26031)
                     /gene="rpsR"
                     /locus_tag="ACL8CG_000410"
     CDS             complement(25792..26031)
                     /gene="rpsR"
                     /locus_tag="ACL8CG_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGS1343071.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(26063..26533)
                     /gene="ssbA"
                     /locus_tag="ACL8CG_000411"
     CDS             complement(26063..26533)
                     /gene="ssbA"
                     /locus_tag="ACL8CG_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGS1343072.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LERRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(26545..26835)
                     /gene="rpsF"
                     /locus_tag="ACL8CG_000412"
     CDS             complement(26545..26835)
                     /gene="rpsF"
                     /locus_tag="ACL8CG_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGS1343073.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(26988..28334)
                     /gene="asnS"
                     /locus_tag="ACL8CG_000413"
     CDS             complement(26988..28334)
                     /gene="asnS"
                     /locus_tag="ACL8CG_000413"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGS1343074.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(28350..28715)
                     /locus_tag="ACL8CG_000414"
     CDS             complement(28350..28715)
                     /locus_tag="ACL8CG_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1343075.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(28708..29895)
                     /locus_tag="ACL8CG_000415"
     CDS             complement(28708..29895)
                     /locus_tag="ACL8CG_000415"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1343076.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAAVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(29892..30380)
                     /locus_tag="ACL8CG_000416"
     CDS             complement(29892..30380)
                     /locus_tag="ACL8CG_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGS1343077.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            30701..31249
                     /locus_tag="ACL8CG_000417"
     CDS             30701..31249
                     /locus_tag="ACL8CG_000417"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS1343078.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(31527..32255)
                     /gene="yaaA"
                     /locus_tag="ACL8CG_000418"
     CDS             complement(31527..32255)
                     /gene="yaaA"
                     /locus_tag="ACL8CG_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGS1343079.1"
                     /translation="MKILIPTAKEMNTDLPSIEATPLKPESQAVLDALALYSASQLES
                     FYKVSAEKATEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(32334..32498)
                     /locus_tag="ACL8CG_000419"
     CDS             complement(32334..32498)
                     /locus_tag="ACL8CG_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGS1343080.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            complement(32665..34260)
                     /locus_tag="ACL8CG_000420"
     CDS             complement(32665..34260)
                     /locus_tag="ACL8CG_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343081.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(34272..34682)
                     /locus_tag="ACL8CG_000421"
     CDS             complement(34272..34682)
                     /locus_tag="ACL8CG_000421"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS1343082.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANHDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(34798..35589)
                     /gene="yghU"
                     /locus_tag="ACL8CG_000422"
     CDS             complement(34798..35589)
                     /gene="yghU"
                     /locus_tag="ACL8CG_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGS1343083.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTVGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(35602..38298)
                     /locus_tag="ACL8CG_000423"
     CDS             complement(35602..38298)
                     /locus_tag="ACL8CG_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS1343084.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38602..39786
                     /gene="mntE"
                     /locus_tag="ACL8CG_000424"
     CDS             38602..39786
                     /gene="mntE"
                     /locus_tag="ACL8CG_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGS1343085.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(39929..41800)
                     /locus_tag="ACL8CG_000425"
     CDS             complement(39929..41800)
                     /locus_tag="ACL8CG_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1343086.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLESTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(41797..42996)
                     /locus_tag="ACL8CG_000426"
     CDS             complement(41797..42996)
                     /locus_tag="ACL8CG_000426"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGS1343087.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNLQAI
                     TEKYQSLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            complement(42993..43760)
                     /gene="dapB"
                     /locus_tag="ACL8CG_000427"
     CDS             complement(42993..43760)
                     /gene="dapB"
                     /locus_tag="ACL8CG_000427"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGS1343088.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWIDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(44026..44874)
                     /locus_tag="ACL8CG_000428"
     CDS             complement(44026..44874)
                     /locus_tag="ACL8CG_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1343089.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(44876..45250)
                     /locus_tag="ACL8CG_000429"
     CDS             complement(44876..45250)
                     /locus_tag="ACL8CG_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGS1343090.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(45324..46676)
                     /gene="glmM"
                     /locus_tag="ACL8CG_000430"
     CDS             complement(45324..46676)
                     /gene="glmM"
                     /locus_tag="ACL8CG_000430"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGS1343091.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSVIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(46700..47479)
                     /locus_tag="ACL8CG_000431"
     CDS             complement(46700..47479)
                     /locus_tag="ACL8CG_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGS1343092.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(47466..48323)
                     /gene="cdaA"
                     /locus_tag="ACL8CG_000432"
     CDS             complement(47466..48323)
                     /gene="cdaA"
                     /locus_tag="ACL8CG_000432"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGS1343093.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            48459..49427
                     /locus_tag="ACL8CG_000433"
     CDS             48459..49427
                     /locus_tag="ACL8CG_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1343094.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(49680..50636)
                     /locus_tag="ACL8CG_000434"
     CDS             complement(49680..50636)
                     /locus_tag="ACL8CG_000434"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGS1343095.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGFYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGSMADKPEFTVEPDGLITVK"
     gene            complement(50636..50971)
                     /locus_tag="ACL8CG_000435"
     CDS             complement(50636..50971)
                     /locus_tag="ACL8CG_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGS1343096.1"
                     /translation="MQQITEIITNGAISILVVLAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            complement(50975..51274)
                     /locus_tag="ACL8CG_000436"
     CDS             complement(50975..51274)
                     /locus_tag="ACL8CG_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343097.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            complement(51284..51634)
                     /locus_tag="ACL8CG_000437"
     CDS             complement(51284..51634)
                     /locus_tag="ACL8CG_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343098.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            complement(51637..51840)
                     /locus_tag="ACL8CG_000438"
     CDS             complement(51637..51840)
                     /locus_tag="ACL8CG_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343099.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(51821..51937)
                     /locus_tag="ACL8CG_000439"
                     /pseudo
     CDS             complement(51821..51937)
                     /locus_tag="ACL8CG_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
     gene            complement(51934..58377)
                     /locus_tag="ACL8CG_000440"
     CDS             complement(51934..58377)
                     /locus_tag="ACL8CG_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HGS1343100.1"
                     /translation="MDALTRRQFDRSMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKHIKQQGGIEAKIQAQIEATDKDFDQKVDKIKKDFNDQVELAKAKAEEVKRE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELAGASSLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQV
                     GGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVSDSPATGFDKAIRLTSSNARD
                     QIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLKDENWTKL
                     SFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATSSKEAPEDIEGQISTV
                     ESTFKQRANSLEAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLS
                     QAEFEVRAGSIHQEILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQD
                     ISKTGIWTTSTYTAAIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIP
                     GSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNES
                     KQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSL
                     DAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSI
                     RQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVT
                     GQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYL
                     FRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATS
                     GTAWVTGIKVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNKN
                     GQRQEALQRYTREESTRQATAVRELVNRDFVGKVTYQEDVKGINQRIEAVKTSANKDI
                     ASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGATTQISNISNRI
                     NSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLARKV
                     ETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNS
                     DFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYV
                     LNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEM
                     DNAYIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDVVADANKKLEATQTKMT
                     LLTGSWAVQNINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDKLK
                     TGNFEAGSVTTTILEAEAVTAEKLKVDNALIKKLTANDAFIDQLTSKRIFSTKVESVI
                     SSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGNN
                     WNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELG
                     SKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDKINR
                     LRMVAFDFIESKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKAI
                     QELNQKIEKMEKTIA"
     gene            complement(58382..58732)
                     /locus_tag="ACL8CG_000441"
     CDS             complement(58382..58732)
                     /locus_tag="ACL8CG_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6711 family protein"
                     /protein_id="HGS1343101.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGARTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            complement(58741..62334)
                     /locus_tag="ACL8CG_000442"
     CDS             complement(58741..62334)
                     /locus_tag="ACL8CG_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343102.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSIATIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLAYAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFAETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIGNIFGNLGSWFGGRWNDSKNALAEANTWLGDKFKS
                     GRDKVNSAFEKVGSWFGDRWNDIKDGVKEADTWFGEKFESAKKKTQNPFQKIGSWFGD
                     RWKDMQDALKEIPNWFKNLFNDAMDNAKNIVKSGIDKLKSFFNFDWSLPKIKLPHFNI
                     SGSFSLMPPRIPSFSVDWYARGGVFNSPSIIGVGEAGQEAVMPLERNTGWISILAQKL
                     AERMPANNVPTGYSLPAGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            complement(62321..62671)
                     /locus_tag="ACL8CG_000443"
     CDS             complement(62321..62671)
                     /locus_tag="ACL8CG_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343103.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYI
                     LSRMITNHVSLLLSNDAKIVELWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            complement(62710..63090)
                     /locus_tag="ACL8CG_000444"
     CDS             complement(62710..63090)
                     /locus_tag="ACL8CG_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6096 family protein"
                     /protein_id="HGS1343104.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVVE"
     gene            complement(63095..63508)
                     /locus_tag="ACL8CG_000445"
     CDS             complement(63095..63508)
                     /locus_tag="ACL8CG_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HGS1343105.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELEYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELTFVDGIGG"
     gene            complement(63511..63879)
                     /locus_tag="ACL8CG_000446"
     CDS             complement(63511..63879)
                     /locus_tag="ACL8CG_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343106.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            complement(63876..64391)
                     /locus_tag="ACL8CG_000447"
     CDS             complement(63876..64391)
                     /locus_tag="ACL8CG_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HGS1343107.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELIISIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            complement(64366..64704)
                     /locus_tag="ACL8CG_000448"
     CDS             complement(64366..64704)
                     /locus_tag="ACL8CG_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343108.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            complement(64685..64996)
                     /locus_tag="ACL8CG_000449"
     CDS             complement(64685..64996)
                     /locus_tag="ACL8CG_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HGS1343109.1"
                     /translation="MSIELLKKLTGEEDTQLLMLFQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            complement(64998..65186)
                     /locus_tag="ACL8CG_000450"
     CDS             complement(64998..65186)
                     /locus_tag="ACL8CG_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343110.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            complement(65196..66221)
                     /locus_tag="ACL8CG_000451"
     CDS             complement(65196..66221)
                     /locus_tag="ACL8CG_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-binding protein"
                     /protein_id="HGS1343111.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFSAALGNVSDNVTMGKEAGANNAYNAILDVSEKLDEL
                     GITKERLLFVTPKFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKKSAQGKTVNRAKAWKTGTAYKEGDTVTHEDKVYVAIKDITSSTNAPGSDSANW
                     KEKTGKK"
     gene            complement(66244..66768)
                     /locus_tag="ACL8CG_000452"
     CDS             complement(66244..66768)
                     /locus_tag="ACL8CG_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HGS1343112.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            complement(67035..>67267)
                     /locus_tag="ACL8CG_000453"
     CDS             complement(67035..>67267)
                     /locus_tag="ACL8CG_000453"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343113.1"
                     /translation="LLKHLEKSKCFFRTQKGLKMDKAKIGITNVEFSGTGGIESATVK
                     LELNIYGADTFSAIELLPKILTDIHSLSYEVD"
BASE COUNT        18864 a        15471 c        12554 g        20378 t
ORIGIN      
        1 ttcccttagg taaccatcta cgaatgagcc tgttgtgatt ctcattagtt cccctttccc
       61 aagaggcata ggggtgcgca taatagatgt gctcctcaga aaacacatca aacaagcgat
      121 tgaattccgt tccattatct gccgtgatgg aaagaatctt gtgttgtttt aagatgagtt
      181 ttagagcctg attgaccacc tcagcacttt tatttggaat caatcggatg atctgatgtc
      241 tactctttcg atccgtcaag acaagcaagc agtagttttt cgctctcgta agtagaaccg
      301 tatcaatctc ataatgccca ttctccaaac gaagattgat agcttcaggc cgctgttcga
      361 tggattgacc agcaggttta aagttggtgc tggcctgttt cttaagcgct tttccttttc
      421 tagggtaaag cagatcctgc ttgctttacc ccaattttcc atgatgaatc caatagtaaa
      481 tggttgaaat tcccacgtta acccctttag ccataaccat catttcaggc aaaaattttt
      541 ggttatgata gtggagaatc ttttccttta gttccttggt cacgcttgat ctcttgaccg
      601 agtgcttgcg attattttca taagactgtt gagcatagtc ggcagaataa acctctttga
      661 agcgcccttt tccaagacat tttcggactg tcctacgctt gattttagtg tggatagttt
      721 gaggagcttt tccaagcaga gaggcaattt ctctatttga tttccctttg ttcgcctttt
      781 gtagtataat ggttttgcat ctctgtgcct ttcttgtgtt tgtggttgaa caacaagtat
      841 aacacagagg tgttttctta tgcctacaag agctttcatt atttccattt tctttcggat
      901 ttcactctat tctgaaaaac ttgtgtatat ttactgaagc tagcaagtct tacctgtaaa
      961 tttaatgaaa gcaacacaaa atccgagagg ggaatctcgg attaatgtca atttaaaaag
     1021 atagagagtt tttagtttaa ataaattgtt ttaaaatatc aacaacatca cttcttttct
     1081 taacctgata agccttgatt cctaattttg gagctacgat tatattgtcc tcaatatcgt
     1141 ctagaaagac acaatttcta ggttataact ggtatttatc gatagttact catatacatc
     1201 agtccacctc catacttatg tgcgagcctc tctttgtatt atacctccat actcacctta
     1261 cagattcttt tggtaataat atctttgcct aatgtagaga tagtcttgca aagaaaaaac
     1321 ttccttgtag ccatgtttct gataaaagtc cggtgcctgg aactgataag tattgacaaa
     1381 ggcaaaacaa caatttcgat tcttagcttc actttctgcc tgttgcaata gttttgaacc
     1441 gattccttgc cctcgcagtt cctcttttac aaacaaatac tcgatttcta gccaatttcc
     1501 aaaagtctct gctatcaaac ccgcaaggag attgcccttt tcatcttcga cataaagatt
     1561 aagtggctca ctttcagcct cttccctttt tgaacggtta taaacacgaa tcagattccc
     1621 tatttcttgc gatttatgtg attccttatt ttccaatcta aagtataatg aaatgaaata
     1681 aaacatgcgc aaatcgatta aggaatttaa tctaatttct aataatgtct tagaaatcaa
     1741 agtttactat tttaacttca atgcactata catctaatac tcaatgaaaa tcaaagagca
     1801 aactaggaaa ctagccgcag gttgctcaaa acactgtttt gaggttgtag atagaactga
     1861 cgaagtcagc tcaaaacatg gttttgaggt tgtagataga actgacgaag tcagctcaaa
     1921 acatggtttt gaggttgtag atgaaactga cgaagtcagt aaccatatat acggcaaggc
     1981 gacgctgacg tggtttgaag agattttcga agagtagcaa aatggaaaaa ggagtgagtg
     2041 aagcacatcg cctccccact cctttttctg tttttaggct gttttttcaa ccttcaagat
     2101 ttttacatca tagctaccaa caggcgtttc aattgttgct gtgtcacctg ttttcttgcc
     2161 aatcaaggcc tgcccaattg ggctttcatt tgaaacctta cctgcaaagg catccgcacc
     2221 agctgaacct acgataatat aaacttcttc ttcgtcctcg ccaatttctt ggatggtgac
     2281 tgttttacca atcgctactt cgtcctgggc aactgcgtcg ctattgacga tttcagcata
     2341 gcggattttt gtttctaagc tagagatttg tccttcgaca aaggcttgtt catccttagc
     2401 tgcttcgtac tcactgtttt ctgaaagatc accgtatgaa cgggcaatct taatgcgttc
     2461 taccacttct ggtcgacgaa ccaatttcaa ttcttctaat tctttttcaa gtttctcctt
     2521 ttcctcaagg gtcataggat atgttttttc tgccattttt ctcaactttc ttctgataat
     2581 attttctaaa gaaaattatg tgacgtatca cataatttta gtttgtttag tttaatttgc
     2641 tgttgacatg ttcagcgaca ttgcggtcgt ggtcttcttg attgttagca tagtagacct
     2701 tgccttctgt gacatctgct acaaagtaga ggttatcgct cttagtttga ttgatgcttg
     2761 actcaatcgc atccagactt ggactatcga ctggaccagg catgagacct acatttttat
     2821 aaacattata aggtgaatca atgttggtat caatcgcaac atcctcagct agactgatat
     2881 tttgccccag ttttccttgg gcatacaaga ttgcaatatt actttgaagt ggcatatcac
     2941 gatttaaacg attgtagaat acacctgcaa tgagcttacg atcttctgtc ttggcacctt
     3001 ctttttcgac caaggaagca atggtcaaca actcattgac agtcaaattt ttagatttga
     3061 tagtactata gtaaggagat aggttcttat ccatagcagc taacatctca tcaatcaagc
     3121 tctcaatagt tgtgctttcc ttgatagagt atgtagctgg gaaaaggtat ccttccaaac
     3181 gataacgcgc accgctgtct tttacaggca aactttccag taaagtagga tatttcgcta
     3241 ctgcttgact gataaacgtc tcatcttgaa ctttagccaa gaaagcctcc gctgtcaaag
     3301 actctttgaa gtcaccttgc aattgaccca cagcttgagc aatctgatcc aaggtataac
     3361 cttctggaat tgtcaaagtc gcaagtacag gttcttgcgg ttcatctgtt ccaccttttt
     3421 gcaactcttt gagtaagtct tctgtactca tactcttttg caaattgtag taacctgctt
     3481 tcaagtcggt ataattttta tacttggcat aaaaactaaa aatcagacca tgctttacca
     3541 aaccagcttt ttcaagcgtc gtaccgattt cttgaacgtt tgaaccttct ggaattccaa
     3601 ccgtcacata tttcttagaa ttagcatcga taggtaacaa agaatctagc acgtactggt
     3661 aaccaaagta accacctgct gagagcaagg caaggaatac aaggaatgaa atcacaaaag
     3721 ctttcacatg tgacttcttc tctttcttag gattaacggg ttttgctcct tctctacggc
     3781 tacgacgtga tgtatcgctg atgatatcca ctgtttctgt agcaggcgta ggtgtttctg
     3841 gacctgcttg ttctgctttt ttctctgccg tcgtatagga aacagctacc cttgttgggg
     3901 tttcattgta ttctctttca agtttcttag gtctaacagg acctggacct ggtcttgatc
     3961 cactttcttc cgctggagaa gaaggtacat cttgacttgg atgacttgga acaccaggag
     4021 tttctctttg aatctcatct gctggagaag ctggtacacc ttgacttggg tgagtagaca
     4081 cggtaggagc ttttctcata atctcctcta ccgttgacaa ggaatcagcc atgagttctt
     4141 cagctgaagg ttcatttgca ggagtgcgaa ctactgcctc atcttctttc agaacttcat
     4201 catagccttt tactttttct aaatctctca gaatctgctc tttaaagctt aatttctctt
     4261 cttctcttga cttttcactc aaaagttttt cctccttgtt gataatccat aatattatat
     4321 cttaaaagtc caaaaaaagc aatctatgat acttttccta acttattttt tcatttccca
     4381 gaccatatca taccatgttt cccctgcaaa ggttgactgg gactggcctt cgttgacaaa
     4441 tccatgtttt tcatagtagg cgatgagata gtcatgacag gttagattaa tgccatctct
     4501 ctcatcttca agagcaactt ctttcaaggc tgtcagcaat ttctgaccca gtccgagtcc
     4561 ctgtgcctcc ttggcaatag acagacaggt cacagagata taaccaccag gctcatgact
     4621 atagtctttt atttcttctg taaaagactg gtcttgcaga tggcggtgca ggccaactgg
     4681 tccttcgata taacccatga ttcttccttc tttttcagca accagaaaag aggtctgaat
     4741 ttctctcaaa tgtgcttcaa agacagaagg aggaatggct tcttcgaccg aaaaattttc
     4801 aaattcaagt tcaacaatcc gatccaaatc ttctaatctt gcttgtctga ttttcattgt
     4861 tcctccagat aaaagggatt aaaccaaatc atactatagc cctggctagt tgcatagagc
     4921 aaagttgctt cttcatcaac aaaaccgttc atttcaaaat aggaaagcag ctcatcagga
     4981 ctctccaaac gaatcccttt gtaatccagc tcaactgcca cctctttcaa ggctgcaaga
     5041 agaagtgttc ccaagccctg tctctgatgg tcagactcga tgactaaaga atgtactttt
     5101 agatattgcg gattgtctga ctggggactt gataaaatat agcctaaaag ttgattttca
     5161 tccctagcta gaagaaaggt atccgcacac ttacggatac tttcttctaa aatatgggaa
     5221 agttgctgct tttcagctgg aaaagacgag gtctgaagtg cccctatctc aggcaaatca
     5281 gacttgcttg cctgaatgat cttaattgga atttccatgg gaacatccta ttgaacattg
     5341 cttgtcaagt tagacaagag acgctcaaat gagtattcat aggtttggat gtctcctgct
     5401 cccataaaga cgtaaacagc attgtcatgg tctaggagcg gagaaacatt ttcaacagta
     5461 atcacttggt gttttttgtt gattttgttg gctaggtctt ctaccttaac gtcaccatga
     5521 tctacttcac gagccgagcc ataaatttgc gctagataaa cagcatctgc ttggtttaaa
     5581 gcatgggcaa agtcgtccaa caaggcaatg gttcttgtaa aggtatgcgg ttgaaagact
     5641 gctacaattt ccttgcttgg gtatttctga cgagccgcat ccaaggtcgc aataatttct
     5701 gttggatggt gggcaaagtc atcgataatc actgtatcat tgacaatttt ctcagtgaaa
     5761 cgacgtttaa caccggcaaa tgttttcaag tgctcacgca ccaagttcaa atcaaatcct
     5821 gctgtgtaaa gaagaccaat aacggctgtc gcattcatga tattgtgacg accaaaggtt
     5881 ggaatgtgga attgccccaa gttttgtcca cggaaatgaa cggtgaaggt tgaaccagtt
     5941 attgaacgaa gaagatcact agctacaaag tcattgcctt caacttcaaa accataataa
     6001 taaattggtg catcagacgt aatcttacgc aattcagcat cttcaccata gacaaaaaga
     6061 cccttggtga tttgtttggc atagtcgtta aaggcattaa aaacatcctc gagacttgtg
     6121 aaataatctg gatggtcaaa gtcaatgttg gtgataatag agtattctgg gtggtaaggc
     6181 atgaagtgac gctcatattc gtcagattca aagacaaaat atttggcatt ggccgaacca
     6241 cgacctgtcc catctccaat caagaagctg gtatctgtaa tgtgagacaa gacatgagac
     6301 aacatacctg tcgttgaagt ttttccatgt gctcctgcta ctcccatgct aacaaagtca
     6361 cgcataaagc tacctagaaa ctcatggtaa cgtttgtagc tgataccatt ttggtccgca
     6421 taggcaattt cgacgttgtt atctggacga aaggcatttc cagcgataat ttccatatca
     6481 ccgtctagat tcttttcatc aaaaggaaga atggtaattc ctgcctgctc aagaccgcgt
     6541 tgggtaaagt agtacttttc aacatctgat ccctgaacct tgtgccccat ctggtgcaac
     6601 atcaaggcca aggcactcat ccctgatccc ttaattccga taaaatgata tgtctttgac
     6661 atgttttctc ccctattctg tcattctggt cagattcaac tcttgggcaa cccgacgttc
     6721 ttgttctgtt tgtttacttt ttttattgta gatttggctc ttctttagaa aatcataatt
     6781 gtttttcttt ggagcaggtg ctgacacttc ttcattcttg gtagggatag aatgaacttc
     6841 ttccgccaag atataatgag actgggtcaa tttttggcta tatttgacaa attcaccagg
     6901 attttccttt tggaaaggag ttgtcggttg attgccctgt ctaactagac tgggctgaga
     6961 atgacgtctc gcaaggctga aatcctgagt taggtagtta gcagagcgtt tctttttcaa
     7021 gtccgcacgc gcttcttcac gcgccacctc cgcatagctc tttccttctt ttttaacccc
     7081 taaaggagcc tttttaggtt tttcgacttg cttttcaatc ggttttactg gtttttcttc
     7141 agcaatagga gcccattcta aataattttt atctcgatac tcacccttga tattactgat
     7201 cagatcagac tcatcataga gattcatgac tggcatttca gtcaacatga cctcgtcatc
     7261 tgacaccaat ggaaatcgtt cttgtttcat tttctatttc ctttcaacac ttcattatag
     7321 cgtattgtct tgatttttca agtgctggct tcagaaattc ccaaaatttc tctaatttct
     7381 gctagggtca gactaccacg tgactctgtg ccgtccaata cttgtgacac cagatgtttc
     7441 ttttgttctt ggagttcctg aattttttct tcaatggttc ccttggtcac caagcgatag
     7501 acctcaaccg tttcttcctg acccatccga tgggcacggc caatggcttg cgcttccacc
     7561 gcaggattcc accaaaggtc aaccaagatc actgtatctg cacctgtcag gttcagaccg
     7621 accccaccag ccttgaggga aatcagaaag gcatctcttt ctccttggtt aaaggccttg
     7681 gtcatgtctt gtctttcctt ggctggggtt gaacccgtaa ttttaaagga agtcaggccc
     7741 aagtctggca gttcttgttc aattttttcc aacattccct tgaactgaga gaaaatcaag
     7801 acacggtgtc cgccgtctgc cacctgtacc agtaggtctc ggagactatc tagtttgccg
     7861 ctggctccct gataatcttc cataaacagg gcaggagtgt cacatatttg acgcaagcgc
     7921 atcaaaccag ataaaatttc cacacgactt cgctgaaatt cctgttctga cacttgagcc
     7981 agatggtctc gcatctgttg taactgggca aggtaaatag ccttttgctg gtcttccagt
     8041 tcatttttat aaaccacctc aatcaagtct ggcaattcag tcagaacttc ttctttcttg
     8101 cgtcgcatca cgaaaggctt gataaactga gccactcgct ctgctggcaa tttcataaat
     8161 tctttcttgc ttggcaaaag tccgggcatg acgatttgga aaatagacca caactcaccc
     8221 agatggtttt caatcggagt tcctgacaag gcaaagaccg acggcaccac aaattgtctc
     8281 aaggtctggg caatcttggt ctgggcattt ttcatgacct gagcttcatc taagaaaagg
     8341 aagtcaaagg ccatcccctg ataaagctca ctgtcctgac ggaaggtggc atagctagtc
     8401 acatagattt gatggctatc ggcaagaatc tcctcacgac ttgctttcaa accatgaaca
     8461 acagccacat ccaactgtgg ggcaaatttc tgaaactcat ccgcccagtt gtaaatcaaa
     8521 cccgacggag cgagaatcaa gactcgactt tcttttgtca cttgactagt caaaaaagca
     8581 atggtctgaa gggttttccc aagtcccata tcatcagcca aaatcccacc aaaaccataa
     8641 tgatggagca tctgcaacca gccaattccc ttttcctgat aatctcgcaa gtcagccttg
     8701 acctgagttg cttgcaaagg aaagtcctct ggatgcgtca aatcctgggc cagattctgg
     8761 aattcttgtg aaaaagaaac acggtctcgc ccttcaaaga gatgagctaa actgtaggcc
     8821 aaggatttcc gagcctgcaa ggtcccatct tttaattcaa attgccccag ttcctgtaga
     8881 ttttggcgaa ttttcttggt ttcttcatcg aaaaagtaaa cttgattaga cgaatcaata
     8941 taaaaatcct gattggcaac caaggcctgc atggcttggt cgatttcctc ctgggcaata
     9001 ttttgaaaat caaactggat ttccaagaga cctcccttgg aggcaatctg cacctgagga
     9061 ctcgctaggc tataaagctc ttctagttta tctgataggt caacatgccc gagtttttca
     9121 aagactggaa tgatatcatg aaaaaaatga tagacagact ccgcttttaa ggcctgacgc
     9181 caagattgaa aatcggcttc aaagcccgca gccaaacaga cttggaaaat tctttcttct
     9241 aagtccgcgt cacttgaaaa tggtaattct tctagctctt gtcggctaga tacctgtcta
     9301 tttccataat caaactgaat ttctaaacga atccgattat cttcttccct gtcaaagtaa
     9361 aaagagggcg caaaagtttt gatttgtaga cgttctggag ctgaaacggt gcccatctgg
     9421 ataaaaagag tcagacagga ggccaatttg tctcgatcac tgctatcaaa ttgcaggtat
     9481 ttctttcctt gttgacccac aggtaacact ttaatttcct tgagaagacg catctgctgg
     9541 tctgttaaaa aataaacctg acctttatgg aaaagtactg ctccctgata aaagacattg
     9601 accctaggac tctcactgat ttccatttca aaatagtccg agtattctgt tactgtaaag
     9661 gcaaatagat tggtatcagc atgcatatcc tgaaaaagca gggtttggta gctatccact
     9721 tgatggtcaa attgaaaatg gggcaaggcc atcagtaaat tcacaccctg ctcaaaaaag
     9781 gtcagaggga aaaagaggtg ccgaccttgg ttttggaaaa agaggtctgg aaccagccct
     9841 tcctccgtta gtccgtgcaa gaaagtcaaa agttcttggc tggcatcatc aaaggcttcc
     9901 caagaaagag actcctcata aatcttgcca atcatatacg actttctctg ctcgacaatc
     9961 cttaaaaaaa gtggaatatc ccgaatgaca tagtattttt gtctattgat ttggccgatt
    10021 ctcagagtcc acaagatatg attggttcct gcttccacct gacccacagc tgataactca
    10081 taggcgcatt ctgatttcgg agataaaatt cgattcaaaa acttgccacc caaggtcacc
    10141 ttggtttcaa cggcctcttt ttcttcatga ccttcttcca gactccacaa gatttcctga
    10201 ccacgctcat catttttcag aaaatgctct agcgctgcca aatgcacaca gtagcccctc
    10261 ttttgaaaag aatcacaggc acaaaaaacc aaatcatcct ctaaactata gcgcagttct
    10321 tcttctgcaa cgcgagcgta gagccgattg ttcttttcct tgatgatatc aaccttacca
    10381 gtttcataaa gggcaacacc ttcgatacga actttccccg gaatcaattt agccatattt
    10441 tcacctttac cttatctttt tattatacca tattttcgcc tatgaaaata gccttctagg
    10501 aagacttttc tcctagaaga ctggattttt aacgtttggc aaaagtagcc acaatccgct
    10561 gacagacttc ctgcaacaga gatttgggca tagctatatt gatgcgggca tggagacttc
    10621 cttcctctcc aaaatccaaa ccacggttga ggataacctt ggattcattt ctcaacaact
    10681 cttgcaatgt ttcatcagtc aggtcatagg ctgaaaagtc aagccaaatc aagtaggtac
    10741 cttgcggttt catgaccttg attttagtct cttttccaaa tagatctacc acataattga
    10801 tgtggtcttc aaagacttgc ttgagttcct ctagccaatc tttaccgtat cgataggcag
    10861 cttctgtcgc caaataaccc aagcctgaaa tttcatgctg attattggcc aacaggcgtt
    10921 tctggaaagc cagtctcaac ttaggatttt caatgactgc ataggaattt tttgttccag
    10981 caatattaaa tgttttagtg gcactgctca agacgatagc aaaatttttg aaggcaggat
    11041 tgatggtatt gaaagactgg tgtttgtgac caaagagggt caaatcttgg tgaatctcat
    11101 ccgaaactaa caaaacaccg tgtttttggc agagttggcc aatcttctcc aacacttctt
    11161 tttcccaaac acgtccacca ggattgtgag gattgcaaag aatatagagt ttaacctcct
    11221 cttccaccaa atccttttca agttggtcaa agtcaatctc aaacagacca tccttttcca
    11281 ctaaggaatt agtaatcaat ctacgattat tcaacttgac actgcgagca aagggtgggt
    11341 agacaggcgt gttaattaaa accgcctcgc cttcttttgt aaaggtttga atagctgttg
    11401 agatggctgg taccacaccc tcgataaaga caagagcctc tttgtcaaag ttgtaaccgt
    11461 attgtgtagc ttcccacttt tgaacttcct taattaagtc ttcactggca taggtataac
    11521 cataaaccag ttggtctgcg taagtttgca cggcttggcg gatttcaggc aagaccacaa
    11581 agtccatatc cgctatccaa gctggtagaa cttcactatc cgtttctgtt tctttccatt
    11641 tataggtatg gtgccctaaa cggttgggca ggcttgtaaa atcatatttt cccatctttg
    11701 tcttatcctt ctaaggcttg gcgcaaatct gcaatcaaat ctctagcatc ctcaatccca
    11761 atagacaaac gcaagaggtc atctgtcaaa ccataagaat ggcgtacttc tgctggaata
    11821 tcagcatgag tttgagtcgt tggataagta ataagacttt ccactccgcc caaactttcc
    11881 gcaaaagaga agaccttgag actgttcaaa atatgaggaa tgcgtgtttc atcggctact
    11941 ttaaaggaaa tcatgcctcc acgaccagtg tagagaactt ccttaactgc tggagaatcc
    12001 ttcaaaaagg caaccacttc ttgggcgtta gctgttgagc gctccatacg aagagacaag
    12061 gtcttgagac cacgaagcaa ctggtagctg tcaaatggag acaagactgc ccctgttgta
    12121 ttaagattgt aaaaaagctt ctcgtatagt tctaaactat tggtcacaac cactccagcc
    12181 aagacatcat tgtggcctgc tagatacttg gttgctgaat ggagaacgat atctgctcca
    12241 tcttcaatcg gacgttggta gatagggcta tagaaggtat tgtccaccac cactttggca
    12301 cccttagcat gagccaattt tgctagtttt tcgatatcaa attccaacat caagggattg
    12361 gttggggttt cgatatagag aacatccaca tccttttcta actcggcaat caactcttct
    12421 tctgtattgg cataggtaaa atggaaacga ccttcctgct ccacttggtt aaaccagcga
    12481 aaagaaccac cgtaaagatc acgcactgcc aagaccttac ttcctactgg aaagacgcta
    12541 aaggccagta caatagctga catccctgag ctagtcgcta gggcatagtc tgctgactca
    12601 atagccgcaa agacttcctc agccttacta cgagttggat ttttagtgcg cgtatagtca
    12661 aacccagtag atcgaccaaa ctctggatgc tgataggtcg ttgaaaaatg aagcggtgtc
    12721 accaatgcac ctgtcgcttc atctgactta atacccgcct gggccaaaat tgtgttaatg
    12781 tgtaattcct tgctcataca atacctccaa atctatagta actattgtac cacttatttt
    12841 catcaactca ttttcttctt ttcaagagct agttatagtt tcaaactata taaaaaggga
    12901 gtttttcctg ctccctttaa tagactataa aatggtgaat ctcaaaagac accttcactc
    12961 tatcatttgc tcctgcacaa aacgagcata acgctcatga ttttccagta gttccttatg
    13021 agttcctgag ccagtgattt tcctctcctc taagaagaaa atacaatcca catcttttac
    13081 cgttgacaaa cgatgcgcta taatcacaac cgtcttctcc tttaatgcag aatagaggat
    13141 actgataatc gcatactcag aatacgcatc aagattagca gtggattcat caaatataag
    13201 aatttcagca tcttttaagt aggttctagc tatttgaagt ctttggcttt gcccccctga
    13261 caagaatcgt ccgcgttcac caacttcagt atctagtccc tctttcatgg agcgaatctc
    13321 atcacctagt gatactaagt ctagcacttt catcaattca tcatcagtta ctaagcgatt
    13381 caaaccgaga caaagattgt cacgaatact gccagataag actgcattat tttgtgaaac
    13441 ccaagcgatt ttacttctcc attcttttaa gttaaaatca tatatacttg attgctccat
    13501 tagaatatct cctgaaagcg gtttataaaa ctgctctaac aaacgcacaa tcgttgattt
    13561 tcctgatcca gatggtccaa caaaagcaat tttttgcccc ttgaaaattg aacaagtaat
    13621 atcctttaag acaggtcgat tttcatcata accaaaatag acatggttaa aattcaaccc
    13681 ttgtcctgat accgattttc ctcactcaaa tttttcttta ggaactgcaa gcaagttctc
    13741 cagtgcaact gaagatccct tgctcctaga ataaacagtt acaaaattag ctatattact
    13801 aataggatta agtaattgaa agaggtaaat caaaaacgaa accaaggttc ccacagatat
    13861 atatcctgcg ctgacccgat aacccccata ggttagcatc acagctatag tcgcaaagat
    13921 aaataagaga gcaaacgggg tctcaaaaga agtaacccta tctgatttca gtgaattgtt
    13981 ttgtaccctt tcaatacaat tatccaaaac atcctgtaca cttttctctg cttggttagt
    14041 cttaattaat tcatgttctt gaatcttttc agtcaattgc cctgttaaaa atccgatttc
    14101 ctcctgtaaa cgacgactat acttttcact gatattggaa aggggcaaga taataaacat
    14161 catacaagga agagtgatga ataaaagtag agaaagattc caatcaagac taaataagac
    14221 tacaatggaa ccaagtacca taactaaact cagaataata tttgggaaag tcgtaattaa
    14281 aaactcacga atgacactcg tgtcattgac aatggcagaa gtcaactccc cactttggct
    14341 cttatcaaag aaggatttct ctgcataaat caacccctct atcacttttt tcctgatttt
    14401 tgctatcttt ttttcacccg attgactaaa cagatagtaa ccaatagaag aaaacaaggc
    14461 ttgaccaata aaaatcaaaa acgattgaaa tactttggaa cctatatttt caatagaact
    14521 cccatctatt aaacccttta agataagggg aagcaacaaa gcaagtagac tagacagaac
    14581 aagtaagaaa ctccccataa tcaccttagt atctactctt aataatttta atttcataaa
    14641 tactccttat aatatttcaa cggataaagt cgggaataac tcaatttgag gataaaatct
    14701 aataaatctt cctataacaa aacgcataac atctaggatt ttatatacct gatattatgc
    14761 gtttttaagc acaaagactt cttacacaaa cttatctaca attagatttt atttgacatg
    14821 ttttgccaat tcttcttggg cttttttatt ggattcttct ttttctttca accatttttc
    14881 tctggctttt gcatattcgt ctgttgtgac aatcttatct tgtactttga ggtatttata
    14941 tgattcaacc ccttttgtac cggttaaacc ataggcagca gcaaatggta cggttcttct
    15001 caatgatggt gttcccccac gcgaaacact tggaagaact aaagaactat caatcaacca
    15061 agcttgaata tcagcatatt tctcataacg tttggctgga tcttgctctt tattagcttc
    15121 ttccaacatt tgagtataga catccagtcc aactgcctta gccttgtcat tggcctcacc
    15181 aggctctagt ccaagatttt gcagaaatcc tccactatta gtattaaaaa tatcgagata
    15241 ggttgacggg tcttgataat caggtcccca accgccatga tataaatcat agtctttctg
    15301 agcagctgtt tgagcaaagt agcctgaact gtcaaactca tctgatgtta attgctgaat
    15361 gtcaatcact acattatcag aacctaaaac agattcaatt gattgtttga tagaactaac
    15421 tccttgtatg cctactttat ctgttacttc cacagtctta tccaagtgga ttgggaattg
    15481 aacacccttt gcttcgagtt ctttcttagc ttccgcaaac ttagccttgg ctttctcagg
    15541 attgtagtaa gggtcttgac catccgcaaa gttgatacct tgccattcct taccatagtt
    15601 gaccatctta gaggctacaa cttcaccaaa gtcttttccc ttgatactga caaagtttgg
    15661 aggaaccact aggttacgca aaatctttgt tgcaccttct ttcccttcag actgagcccc
    15721 ataagatgtt ctgtcaaaag caaaattgat agcctgacgg aagtttttat tgagaactgc
    15781 ttcctgggtc gatttctttt caatgtcact tgttttagaa gtataattgt aagacttcct
    15841 atctaggtta aaattaaaga aatatgaagt tgaattttgc atactatgga tgatattgtt
    15901 tttgtatttt tctttaatcc cttcatagct ggagctgtta ggaaaaagac gagccgtagt
    15961 ataagcacca gctgtaaaat tacgttccag tgattcttgg tcgctaccat catagtaggt
    16021 caatttcaca tcgtctacaa agacattatt agcatcccag taattagggt ttttcttata
    16081 ttcaatagca gattttgaga caagtgcttt catcaagaaa ggtccattgt acaaaatact
    16141 agatggatcc gccttcccaa aatcatcccc ttttgatttc aggaaatctg cattaacagg
    16201 aaaaagtatc gttgcaagtg tttttgaatt ccagtaaagt tctggtttaa ccaaagtata
    16261 ttgaaccgtt tggtcatcaa gtgccttgac accgacagtt gaaaagtcgc ttgttttacc
    16321 agtgatatag tcatccaaac cagcaacaga gtcctgcact agatacaagg cttctgattt
    16381 tttatcagct gcatattgca aacctgtcac aaaatcctgg gcagttacag gcgcatattc
    16441 ttctccctca gaagtaaacc acttggcatc cttacgaagt ttgtaggtat aggtcaaacc
    16501 gtcctgagaa acagtccaat cctctgctaa tgatggaata atattcccat attggtcatt
    16561 ttctaataac ccgtctacca aatttgcaac aatatcggat gttgctgcgc ggttttctgc
    16621 tagatagttc aagctagatg gatcacttga ataaacatag ttgtaggttt ttgacgccgt
    16681 gctagaattt ccacacgcgc tcaataaaac tcctgtaccc aggacaagac ctgccaaggt
    16741 tagatatttg ctcttagact ttttcatttc cagaacctcc tgctttaaat atttgtttta
    16801 ttatacaact cttggtttgt ttagtcaatt gttttttcca aaaaatcaaa aaaaacctca
    16861 ttttctattt ttgaaagata attttagcta tttttacgct aaaaaaggaa taagtttcaa
    16921 gttctcctaa aagattgttc aacttattcc ttttatttat aaatgctacc ttacgaaagc
    16981 ttaaattttg ctcgcaggcg atctgcttgg gcttttccta ttaccttatc taacaaatag
    17041 gtacgcagac tcataaccat ataaagtcca ccccccatgg caccgacaag agctacataa
    17101 aagaagctcc acaaacgtcc acttggttgg aagaaaaatc ctaacagcca ctggatggtt
    17161 cctattaaca gaaacatgac tagggtcagc aaactgatta aaatggttcg cttcaaaatc
    17221 accttgcgct tgacaccagt tactttacaa atatcccgat acatcaagac gttaggaatg
    17281 atgagagcaa tggttgttga aatcaaagga ccataactgt ggaagagggc gatggtaggt
    17341 agttgcaaga ctagcttggc aatagaacca tagataaaat agagaacggc ctttcggttg
    17401 cggaacatgg cctgaagcat tggagacaag accatgtaca agcctaaaat aatagactgc
    17461 aaaactgcaa agacaaataa gcccagagcc aaactatctg gcttaccata gaagactgta
    17521 tatagaggtt ctcctaccat aaccactcca accgttgctg gtagcaagaa cataaagagt
    17581 agggtgagac tgtcctgaac cagacgagaa gctgctttca agtccccctt gacatagttt
    17641 tccgtcaaaa gtggcaaacc aacactccca atcgaaaccc ctacagaaat caaaatcatc
    17701 gtgattttat taggattggc tgagaaataa gaaaacatga caaccaagtc ctcattgctg
    17761 tagttggtaa accagctcat actattgata aaggtcagct gatccaaaat ctggaagagc
    17821 tggatggcag accctgtcag gataaaagga atggcttcct taatggtatc aaccaagaga
    17881 cgcttactgt taatcttatc tcctgtttca aagactcttt tgagtgaacc ttcttgggca
    17941 aggaaataaa tcaagactgc aaaactggct accataccga caaaggcagc aaaggttgat
    18001 tgggtaacgg ctgctagata atctcctgaa ccgagcttca taatgataaa ggttgctagg
    18061 agcatccaga taacacgaat gacctgctca gcaatttggc tcatggcata gggtttgagg
    18121 ttattcatcc cttggaaaaa tcctcggata acactcatag acgggaaaat caagactccc
    18181 caagccaagc tttgcatgat tgggatcaag tctttgccca cgccagacaa gtctgctagc
    18241 caaggagcaa agacatacaa gactaaagca aaaaccaggc ctagtcctgt cataaagcct
    18301 aagaagctcc gaatcagggc aaagctatgc tcttcttctc gcatggtatt atacttggca
    18361 acttgcttgg ccaccgcaac tggaatcccc gctgttgaaa ccaacaagaa ccaagcatag
    18421 atattgtaac ccatggtaaa gagaccattt gccttagctg cataagcccc catccagatg
    18481 taccaaggga taatgtaaac agccccgagt aggcgactga taaagttact agccgttagc
    18541 caagcagtcc cccgtaacat ctgggcctgc tggtgattgt tttcgtgcga catagattcc
    18601 tcattcaatt ttgatagcta ggaaaaactc cttatcttcc attataaact tttccttgtt
    18661 acttgtaaat ttacgacttt cggtttacaa tagaaagtat gattaagatt gaaaccgtat
    18721 tagatatttt aaagaaagat ggcctttttc gcgaaattat tgaccaaggt cattaccact
    18781 acaactacag caaagttatt tttgatagca tcagctacga cagccgaaaa gtaacagaag
    18841 acactctttt tttcgcaaaa ggcgctgcct ttaaaaaaga ataccttctt tctgctataa
    18901 cacaaggatt agcttggtat gtagctgaaa aggactacga agtcggtatc cctgtcatca
    18961 ttgtgaacga tataaagaaa gccatgagtt tgattgccat ggagttctat ggtaatccac
    19021 aggaaaaact caaactcctt gcctttactg gtactaaggg taagacaaca gcagcctatt
    19081 tcgcctataa catcttatct caagggcata gacctgctat gttgtcgacc atgaacacaa
    19141 ctcttgatgg cgagactttc tttaagtcag cgttgacaac ccctgagagt attgacctct
    19201 ttgacatgat gaatcaggct gtgcaaaatg accgtaccca cctcatcatg gaagtctcca
    19261 gtcaagccta tctggtcaaa cgtgtctatg gtctaacctt tgatgtggga gttttcctaa
    19321 atatcagccc agaccatatc ggcccgattg aacaccctag ctttgaagac tatttctacc
    19381 acaagcgtct cttgatggaa aatagccgag cagtcatcat taacagtgac atggaccact
    19441 tctcagtctt gaaagaacag gttgaagatc aagaccatga tttctatggt agccaatttg
    19501 ataaccaaat cgagaattcc aaagccttta gcttttcagc tacgggtaaa ctcgctggag
    19561 attatgatat tcaactcatt ggcaacttca accaagaaaa tgcagttgct gctggacttg
    19621 cttgtctccg tctcggagca agtcttgagg acatcaaaaa aggcatcgct gcaacccgcg
    19681 ttcctggtcg tatggaagtc ctcactcaga aaaatggagc caaggtcttc atcgactatg
    19741 cccacaatgg ggatagtctg aaaaaactca tcaatgtggt tgaaactcat caaaccggaa
    19801 atattgctct ggttctggga tcaacaggaa acaagggaga aagtcgtcgt aaggactttg
    19861 gcctcctcct caatcaacac cctgagattc aagtctttct gactgctgat gaccctaact
    19921 atgaagaccc aatggtcatt gcagatgaaa ttagtagcta catcaatcat cctgttgaaa
    19981 agattgcgga tcgccaagaa gccatcaagg cggcaatggc tatcacaaat cacgaattag
    20041 atgcagttat tattgcgggt aagggagccg attgttacca aatcatccag ggcaagaaag
    20101 aatcctaccc aggagataca gccgtcgcag aaaattattt ataagaatag aaaaaatcaa
    20161 gggaaaatga aacccttgat tttttcctat tctttagtaa aaacgttttt caaaccttca
    20221 acggcacctt ctacagcacc ttttgcgtct tctacaacgt cttttgcctt agcaactgtt
    20281 ttttcaacag ctccttcaag ttctgtcttg ctgtctccag taactttacc aaaaccttct
    20341 ttgacagcac ctgttgcttg ttccaatttg ttttcaagtg acatatgatt gtctccttta
    20401 gtttattccg atatgtgtta ccggttacat atagtttata ccgaatacta aggaaagtca
    20461 aacaatgttc tcagaaacaa gaaatcacgc taagtagaaa gttaatctct ccttatcaaa
    20521 atcgatagcc aactcatact ttctatcttc attttgcaca atatagccta agacaaccaa
    20581 actgtccaca aagatatcac ggcatttctg cataagctgg tcttttttga gaaatttcaa
    20641 caaaaaagcc gtcatatact tgagggcata ctcaggatta acatctccta aaatgtcata
    20701 gagctcctgc tgtttttctg tcaaaggata ctgctgtttg accttgtaaa aataattgga
    20761 cagggtcatt ttaatgcgcg caaagtccgt cttttcaact aaaatagctg cattgatttg
    20821 attgcgcaat tccgtctcaa aactctgctc caacaaggct tgatagaccg gactagcttc
    20881 tctgacaaaa atctcttgat ccagttcaag actatcaagt gattcaagcg taggaaaatt
    20941 aaggtaatgg cgcttatttt cacatagaat cacatcctca tactggtcca gatagcggat
    21001 caattctcca aaaatggctg tctcgtcaaa cgagatggat taaaaatctg aatcacgaag
    21061 attcctttct ttacattgta acagaggcga tgctgccaac tgactaggat tggtcccagc
    21121 ttggttcaga ggaacaggca gacctagttc tatgtaatac tccctccaaa aatcactaat
    21181 ctcctgttcc ccatctccaa atttcatagg aatagtttca aaaataggta ggatttctgc
    21241 tatatactgg gagcagtaga aaccagctgc atctggatag aaagaagcat tgtagggtgc
    21301 tccaagatgt ttgcaagctc tttccttcac cgactggata tccatttctg ggtaaacata
    21361 gaggtcgtat aaatgattgg actcaaagaa gtctgccggt tcttgacaga caacaccagc
    21421 ctgtccacta gcatgataaa tcatcccatc caaataaatg gcaacatggc tatagttacc
    21481 tgtggaagtc tggatggcct gtcccatgtc tgacccatct ctcacaaaaa tcaaatcgcc
    21541 attttctaac atacttcact cctagaaaaa aggagccgaa actcctttcg atataaggca
    21601 aactagactt tccgattttg agctgacacc caaaatctta cgcattaaag ctttcagtca
    21661 attgaggtac cacttgtttc ttacgtgaaa cggcaccagc aaggaaggca tgattgtttt
    21721 caagtttgaa gttgaaagcc gcttcgacct tgtccatatt ggcaccaaga gccaagattt
    21781 ctgagtttga gttgacgata tctgtaatca tcaagacaaa gtcagagtag ccgtttgatt
    21841 cgttggcagc ttgcattgca gcttcaattt ctgcttggcg ttccaaaact tcagcgatgt
    21901 caactgtgtt cacttgggca acacggacat tatttccgtt gagttcaaaa gtcttagcat
    21961 cgatgtcaat caattcttca gcagatttgc tagccaagtt ggtaccagct ttcaacattg
    22021 ccaaaccata ttcttccaag ttcacaccag ccaattcagc caattcagga gcaatgattt
    22081 tatctgttgg gtgtgttgtt ggtgatttca aaagaagggt atctgaaatc aaacctgaaa
    22141 gcatcaaacc tgcaatctct ttaggcacag ctacaccatg ttctttgaac atacggtaaa
    22201 cgattgaaga cgctgatcca actggctcca aacgcatgta aagtgggctt gcagtttcaa
    22261 agttagccac acggtggtgg tctacaacac cgtaaacttc tacttcagcg atatctgata
    22321 cagattgttg gaattcattg tggtcagtca agataacttg ctctgccccc tctgctttgg
    22381 cagaagtgat aacacgtggt gcttccacac caaaatagtt caagacaaag gctgtttctt
    22441 catttggagt tccaagggca acagcttccg tatccaaacc gtaagcttct tttgcaaggt
    22501 aggcaaaagc tacagatgat ccgatggcat ctgagtctgg attttggtga ccaaatacta
    22561 gaatcttgga catgataata cctcattttg tttattttct ttattgtagc atttttttcg
    22621 ctttttgaca aaggtaagag gagtcaaagg actccccacg attcttcaaa ataactgagt
    22681 aaatttctat cttgattttc agataaaaat tcttccttct gtggcctctt cttacgcttg
    22741 agaagagctt cagccgacat ggcttcttcc ttactggcaa aaccttgagc atagataagt
    22801 ttgactggca agcgtgctcg tgtatatttg gctcccttcc cactattgtg gatagcgagg
    22861 cgtcttctca tatcagtcgt atagcctata tagtaggatc catcacgaca ctccagaacg
    22921 tacatataag ccttatgatc cataataaat ctcttcgatt tcgggcgtat aagagccatc
    22981 atcattgtgg acaatcaaag gaggtaagac cttaaagcca cttgttgagc catccttgat
    23041 cgcctcaatc aaaagcatat tggcttcctt ttctcttttt ggataaacaa actgcaggcg
    23101 cttaggggct agattatgtc gttttaacgt atccaaaata tccagaagtc gatcaggacg
    23161 atgaaccatg gccaaacgcc cattagactt gagaatactc tgggcactat gacagatttc
    23221 ttccaaatta gtcgtgattt cgtgtcgagc caagagataa tgttcactct cgttcagatt
    23281 agaataagga tccaccttga aatagggtgg attacacaaa atcatatcca ccttactccc
    23341 ctgaatgtga gcaggcatat ttttcaaatc atcgcagatg acctgcattt gctcctctaa
    23401 tccattcaaa cggacagagc gttcagccat atccgccaaa cgctcctgaa tctcaacaga
    23461 caatatctgt gcttgagtac gagtgctagc aaaaagcccc actgctccat tcccagcaca
    23521 gaaatccaca atcaacccct tcttaggaaa acgtggaaat cgtgataaga gaacactatc
    23581 caccgaatag ctaaaaacct ctctattttg aatgattttg atatctgtcg aaaagagctg
    23641 gttaatgcgc tctcctgatt ttaataattg ttcttcttcc atggtcctat tatagcaaat
    23701 ttatattaac attacaaaaa atataaaact ctaaactact tcttcttttt taaatggtgc
    23761 agggcttctc cagtccagat tggtagcatt cgtcgaaagg gagcaaaacc gtagttaaag
    23821 cggtcgcttg aaaagcgtct ccgtctagga aactggtact tttcttcctc caaagtgcgg
    23881 atagaaagac tggctttccc tgtaaattca tctaaatcca ctacctgaac ttgaacctct
    23941 tcatcgactt tcaaggtttc atgaatattt tcaataaatc ctgtccgaat ctctgaaatg
    24001 tgaatcagcc ccgtatcacc cgtctctaac tcaacaaagg caccgtaggg ctgaatccct
    24061 gtaatacgcc cctttagctt atcaccgatt ttcatcttag tcctcgattt caatagtttc
    24121 aattacaaca tcttcaactg gcttgtccat agctcctgtc tcaacagcag caatgacatc
    24181 caagacagcg taagatgctt catcagctaa ctgaccaaaa accgtgtgac ggcggtctag
    24241 gtgaggtgtc ccaccttgat tggcatagat ttctgcaatc ggttctggcc aaccaccacg
    24301 agtaatttct ttcttagaat aaggtaggtg ttggttttgc acgataaaga actggctgcc
    24361 gttggtattt ggaccagcat ttgccatgga aagagcacca cggatattgt aaagctcttc
    24421 tgagaattca tcctcaaaag attcgccgta gattgactcg ccacccatac cagttccagt
    24481 tgggtctcca ccttggatca taaagtcctt gataatacgg tggaaaatga caccatcata
    24541 gtagccatct tttgaaagag atacaaagtt agccactgtt ttaggagcat gttcagggaa
    24601 aagcttgata cgtaagtctc cgtgattggt cttaatagtc gcaagaggac cttctactgt
    24661 ttcaatgtct acttgtggaa aatgcaattc tttttctacc ataccaaata cttctaaggc
    24721 atcaaaaatg ccatcttctt ctaatgtttt tgtaatataa tctgcttttt ctttgatttt
    24781 atcatgagaa attcccatgg caacgctgat tccagcataa tcaaagagtt ccaagtcatt
    24841 gagaccatct ccaaaaacca tgaccttctc tggtttcaag ccaaggtgtt ccacaacctt
    24901 ttccaccccc gtcgctttgg agcctgaaat cggcacaata tcagacgaat gttgatgcca
    24961 acgaaccatg cgaagtttgt ctgagagact gtcaggcaag tgcaagtcat ctcccttatc
    25021 ttcaaaagtc cacatctgat agatatcttc tttttcatgg aaatcgggat ctacatctaa
    25081 gtcgggataa attggattga tagcttcact catcatatcg gtgcgagtcg acaacttggc
    25141 atcatgactc ccaaccaagc catactcaat tccttcttgc ttagcccaag agatatactc
    25201 ctcaacatct gacttttcaa tctgatgctg ataaatgacc tgaccttttt tatcttcgat
    25261 ataagcccca ttcaaagtta caaaaaagtc aggcttgaga tcacgaatct ctggaacaac
    25321 accaaaaatg ccacgtccag aggcgattcc tgttaaaatt cctttttcac gcaactgttt
    25381 aaaaacagtg ggaattgtag ttggaataaa ccctgtcttt gaattccgca atgtatcatc
    25441 aatatcaaaa aagacaatct tgatcttctt tgccttgtat cttaatttcg cgtccatctc
    25501 actacctctt tcaatctaac tctttccatt atatcataaa gtaggcaaat cccctatttt
    25561 caaaaagttt atcattttta ttttaatttc ttggatgaga aaagagacat atttatgaaa
    25621 aagctccatc gtgcttttaa tgtgttctct tgttttcaaa ctcgtaaaaa gggagccact
    25681 gagcctaact cgctctctca tttcaaagct tgtgaaaaaa gacccgttgg ggtcttaatt
    25741 cgctttcttg ttttcaagct catgaaaaag agacccaact gggtcttttc tttaatcttc
    25801 gtttacgaaa ggcatcaaag ccattacgcg agcgcgtttg atagctgttg ttactttacg
    25861 ttggttttta gctgaagttc ctgttacacg acgaggaagg attttcccac gttctgaaac
    25921 gaaacggcta agaagctcag tatctttgta atcaacatat tcaattttgt ttgctgcgat
    25981 gtaatcaact tttttacggc gtttgaatcc gccacgacgt tgttgagcca tgttttttct
    26041 cctttataag tttagttgtc cattagaatg gtaaatcatc atctgaaata tccaatgggt
    26101 ttgttgctcc aaatggattt tcattacgtg aaaagtctgg tactgaattt gtaggtgctg
    26161 aatagtttgc agttggtgca gagtaagctc cacctgtgtg accctcacgc acactacgtc
    26221 tttccaacat ttggaaattc tcagccacga cctctgtcac gtagacacgt tgtccttgct
    26281 ggttatcgta actacgagtc tggatacgac ctgtcacccc gataagtgag ccttttttag
    26341 cccagttagc aagattttca gcctgttggc gccacataac gacattgata aaatcagcct
    26401 cacgttcacc attttgactc ttaaatgtac ggtttactgc aagagtaaaa gtcgcaactg
    26461 ctacatttga tggggtataa cgcaactcag cgtcacgtgt catacgccct acaagtacaa
    26521 cattgttaat catagtttac cttcttacgc gtcaattttg acgatcatgt gacgaagaat
    26581 gtcagcgttg atttttgaaa gacggtcaaa ctctttaaga gctgcatcgt catttgcttc
    26641 aacgttaacg atgtggtaaa gtccttcacg gaaatcttgg atttcgtatg caagacgacg
    26701 tttttcccaa gtttttgatt caacaacagt tgcaccgttg tcagtcaaaa tagagtcaaa
    26761 acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga tataaagaat
    26821 ttcgtattta gccattgata tgttcctcct tttggtctaa tgaccccaag actttgcaag
    26881 gggtaagtga ggttcgctca caataaacta ttatactaga aaaatttttt ttacgcaagt
    26941 aaaaacacta gaattcgaaa aaacgccaca tgggcgtttt cctgttctta tggtttgata
    27001 cggtgcaaca tacgtgggaa tggaatagct tcacggatat gttttgttcc tgctgcgaag
    27061 gttaccatac gttcgatacc gataccaaat cctccgtgtg gaactgtacc gtatttacga
    27121 aggtcaaggt agaattcata ttctgtacga tccatgccaa gttcatccat cttagcgaca
    27181 agggcatcgt aatcttcctc acgcatagac ccaccgataa tttctccata gccttctgga
    27241 gcaagcaagt ctgcacaaag cacgcgctct ggatttccag gaactggttt catgtagaag
    27301 gccttgatgg ctgctggata gttcatgaca aatgttggca caccaaagtg gtttgaaatc
    27361 caagtttcgt gtggtgaccc aaagtcatca ccatgctcaa gatgctcgta gtcagcatct
    27421 tcatcatttt catgctcttg caagaggtca atggcttgat cgtaagtgat acgtttgaat
    27481 ggctctgcaa tgtagcgttt caagagttct gtatcacgtt ccaaggtttc caaggcttga
    27541 ggcgcgcggt caagaacacc ttgtagaaga gctttcacat aagcttcttg caagtcaagc
    27601 gactcatcat gtgtcaagta tgagtactca gcatccatca tccagaattc agtcaagtga
    27661 cggcgtgttt ttgatttttc agcacggaaa actggaccaa agtcaaagac acgaccaaga
    27721 gccatagccc ctgcttctag gtaaagctga cctgattggc tcaagtaggc tggcgttccg
    27781 aagtagtcag tttcaaagag ttctgtagaa tcttctgccg catttcctga aagaattggg
    27841 ctgtcaaact tcataaaacc gttcttgtca aagaactcat aagttgcata gataatagcg
    27901 ttacggattt gcaacacagc tacttgctta cgagagcgta gccacaagtg acggttatcc
    27961 atcaaaaagt ctgttccgtg ttcttttggt gtgattgggt agtcttgaga ttcaccgatc
    28021 acttcgatgt ctgtgatgtc caactcatag ccaaatttag aacgttcgtc ctctttgaca
    28081 atacctgtca cataaacaga cgtttcttgg ctcaagcgtt tgataacatc aaacttctca
    28141 agtcccactt cttcaccaaa tttttcgaca aagtttggtt taaaagccac accttgaaag
    28201 aaggctgttc catcacgcaa ttgtaagaaa gcgatttttc cttttcctga tttgttggca
    28261 acccaagcgc caatcgtcac ttcctgacca acatagtctt ttacgtcaat aatcgttaca
    28321 cgttttgtca ttatttttcc ttttcttttt tattctttat ggcaaaccac ctctatattg
    28381 ttcccatcca ggtcaatcat aaaagcagca tagtaaatcg gatgctcact tcgataacca
    28441 ggagccccat tgtctcgccc acctgcctct aagccagcct cataacaagc ctgaacttct
    28501 tccttatttt ctgctaaaaa agcaaaatga acaggatctt gtgttccctg agtcagccaa
    28561 aaatcaccac caggatgagg gctgttcggg gatagaaaac taattagaga actagtctta
    28621 aaagccaatt tatagtccaa aggagcgaga aaactcctat aaaatccttc tgaaatttgt
    28681 aaatccttta ccttaatctc aaaatgatca atcattctca ctacccataa atgctttcaa
    28741 gcgttcgact gcttctttaa gcgtgtctag gtctgtcgca tagctgaggc ggacattttc
    28801 tggtgctcca aatccagctc ctgttaccaa ggccacttcg gcttcttcta agatagcagt
    28861 tgtaaagtct gtcacatccg tgtagccttt catctccatg gcctttttga catttgggaa
    28921 gagatagaag gccccttgcg gtttgaccac ttcaaatcct ggcacctctg caaggagggg
    28981 atagatggta ttaagacgtt cctcaaaggc ctgacgcatg ctttctacag tatcttgctc
    29041 acctgataga gcctcaactg ctgcatattg ggctactgct gacggattcg aagttgtttg
    29101 acctgcaatc ttggacatgg cagcgataat gtctgcttct ccaacggcat aaccaatccg
    29161 ccaaccagtc atggcatagg ttttagaaac accattgatg accactgttt gcttgcgaat
    29221 cgcttccgat aggctagaaa tcggtgtgaa ctcatgacca ttataaacca agcggccata
    29281 gatatcatct gctaggatga gaatatcatt ttctacagcc cagtttccaa ttgccaagag
    29341 ttcctcacgg gtgtaaatca tacctgtggg attagatggc gaattcagca ccaaaacctt
    29401 ggtcttgtca gtgcgagctg cttctaactg atctacggtc accttaaagt gattgtcttc
    29461 cttagtagaa acaaagacgg gaacgccttc tgccatcttg acctgatctc catagctaac
    29521 ccagtatggg gttgggatga tgacttcatc acctggattg accgcagcca taaagaaggt
    29581 atagagagaa tatttggctc ccgcagcgac tgtcacttga tttgacgcta cagaatagcc
    29641 gtaaaagcgc tcaaagtagc tattgaccgc cgccttaagc tctggcagac ctgaggttac
    29701 tgtataaaaa gaagcacgcc catctcgaat cgatgcaatg gcggcatctt ggatattttt
    29761 gggagtagtg aaatctggct cacccaaggt tagagacaaa atatctctgc cctcagcctt
    29821 cagtgctttg gcacgggctc cagcagccaa agtcacactt tcttccattt ctaaaacacg
    29881 gttggataat ttcataggcc ctccttgttg accaatgctc ctgtttcaaa atctactaga
    29941 taaaaatcag atcctgactt gacttcccag attggcttat cttgataacg accaaagata
    30001 atcttgtcaa tttcgccagc tcccttttcc ttagaaaccg tttctgcttt ttcttgtgaa
    30061 acaccctgat ttagctgata aacgtaaatc ttatgatcat cttttccaat cagaacagca
    30121 agtgcttctt gctgtttatt acgaccaaga acgctgtaat aagattccaa gccattgtat
    30181 aaatcaacct gatcggcctg ctctaatcct gcatactgct gagctaattt ttctccttca
    30241 cttttagctg tttgataggg tttcatgcta agagaaacca tatacagaaa ggaagcactg
    30301 ataaccacaa acaaaatcgt catccctaga ccatactgcc acagtagatt attttttgct
    30361 ttgttttgtc tttttttcac tcgtctattt taccatctat taagctttat tacaagtgaa
    30421 tataagaata ctcttcgaaa atctcttcaa accacgtcag ctttatctgc aacctcaaag
    30481 ctgtgctttg agcaaccaat tctatttctc ccttcaaaca aaaccgattt tgaaagtgaa
    30541 acagttctta ctttttcagt cacaaatgac tagagtttcc gaaattttac aattttcaaa
    30601 taaactctga gcaaatttct tgcaagttct tttgttttgt tgtaatatat tttataacaa
    30661 cgagagagtt ctcgaaattt taagaaaaag gagacacatc atgtctaaaa aagtattatt
    30721 tatcgtcgga tcactacgtc aaggttcttt caaccaccaa atggcgctcg aagctgagaa
    30781 agcacttgct ggtaaagcgg aagttagcta ccttgattat tcagcccttc ctctcttcag
    30841 ccaagatttg gaagttccaa cacatccagc tgtagctgct gctcgtgaag cagttctcgt
    30901 tgcggatgct atctggattt tctctccagt ctacaacttc tctatccctg gtacagtgaa
    30961 aaacttgctt gactggctat ctcgtgccct tgacttgtct gatacacgtg gcgtttctgc
    31021 ccttcaagac aagtttgtca cagtatcatc tgtagccaat gcagggcacg atcaactttt
    31081 cgctatctac aaagacctct tgccatttat ccgtacacaa ggcgttggtg atttcactgc
    31141 tgcacgtgtt aatgactctg cctgggcaga cggaaaattg gttcttgaag aaacagtcct
    31201 aaactcactt gaaaaacaag ctcaagactt ggtcgaagct atcaagtaac taacactcaa
    31261 taaaaatcaa aaagcaaact aggaagctag ccgcaagctg ctcaaaacac tgctttgagg
    31321 ttgtagatag aactgacgaa gtcagtgaca tatatacggt aaggcgacgc tgacgtggct
    31381 tgaagagatt ttcgaagagt ataacataat aaaagcgaac aagactactt ttctgacact
    31441 cagaagacta gcttgttcgc tttttttctc atttataaac taaaacagct gatgatacat
    31501 attgccaaat acaaaatatc tgatttctat acttccttta caaaaaccaa tccctgtggt
    31561 tgtgacaaat cttctcggta aacaaatcca gcaaagttca agcgacgtgc ttcccccaca
    31621 gtttgtactt gattttctat taaagctgtt agaaaggccc cgcgcgcttt cttggagata
    31681 gttgagtgaa tcttcagctg accgcctcta tcctccatga atttgaaggt caccatcttt
    31741 gctctgattt ccttagaaaa tacagtctca aactctgatg acaagagaga gaaaatcact
    31801 tcttccttct tcagagcttc atcatagact gccttccaat ggctcttcaa agtcttacca
    31861 gcgactttta atttcatcaa aaaatccaaa cggtgaggag ccatgggtga caaggctgga
    31921 acaacaccgt acaaagccga ggtaatgaag acatgatttt caagataatc ttgttccgcc
    31981 tcggtcagct tatctctctt aatgttgcgg tacataagcc catcaaaaag tttcaaggct
    32041 ggatagtgtt gagcagtttg ccttttcaaa gcttggatat tttgaaattc ttccgtcgct
    32101 ttctcagctg ataccttgta gaaactctcc aattgactgg cagaatagag agccaaggca
    32161 tcaagcacgg cctgactttc tggttttaaa ggagttgcct cgatacttgg caagtctgtg
    32221 ttcatttctt ttgctgttgg gattaaaatt ttcatattga tagtgtagca tattttttag
    32281 ccacaaccaa gaaattcatt tgaaaaacct cggtttgact gaggtttttc tatttatttg
    32341 ggccatccta accagacagc cgcgagaaca agggctatgc cagctaaact tgttaagata
    32401 gataagaatt tatctttttt ctccttgaac tgagaaaaac ctatcttcaa agcgagcagt
    32461 ccgagtagca ttgaagcaac catcaaataa aaacccattt ctttgtcctc cattaggctt
    32521 aatttacctt attataacat atatttatta aataaacctt ttttatactc aatgaaaatc
    32581 aaagagcaaa ctaggaaact agccgcaggc tgctcaaaac actgttttga ggttgcagat
    32641 agagctagag attttcgaag agtattattg tactttaaag gtcttgagat aattgtcttt
    32701 tcctacttga ccttcgaagg ttttaccatt ttcaaggtaa ggaaggtcat cggatactga
    32761 agccttgacc ttgtatatct tgccatcaac tttaaagaag tagacagtgt ctcccttgat
    32821 aacagctgat ttgaggtctg ctactactcc attgatgctt tctgtcgttg cattgtcaat
    32881 ttcaaggtcg tttttattgg catacttgct gagcatctct tccactgtag tagcaacgat
    32941 aacattttgg tactcgactg cgtctaccag ggcgtactct ttgaccaagc cagcattgtc
    33001 cttcaagccc atgatgtaga gaggcttgtc attgaggttg atgaggattg ggaaggttgc
    33061 tttgtaggat ttctcctgaa cagcaccttc tgctgattca cgggctgatt cttctgtcgc
    33121 agaagccaag ctatacttag tgatttctcc tgttcgcata ttttcaagga tgaaaccaag
    33181 attactctca tccgcattag ccgacgtcac acctgtgtag agatagatgt cattaccgat
    33241 agacaagtaa ttatagccct tggtagtctg ggtcacgttt ttcttggaaa tcatggcatt
    33301 caagaaaccg tccttgtact tgccgttgta gttgatttgc tcaatggttt cctctgctgg
    33361 atagatcctg tccacccatt ctggaacatc tgataagctg tattccttgg tttctccatt
    33421 tgtagcatcc aagataatga ctgaagcagg acgaggaaca gcaagtccaa attgcttttg
    33481 gtaaaccgtt gctacataga aaggattgcc ctcatcgtcc acctcaaaag atggagtttt
    33541 aaagattttg gtcgggtact tcaagcgcag gtgacgtttg acatcacggt taaaatactc
    33601 cgagtctgaa tacttgattg gtgtcttcaa gtccaccaaa tccgcatttc cagttaccat
    33661 gtccaccttg atatactcac cgattccctt ggcttgattg ttaaaccatt tgatagggtc
    33721 tgcatattct agtggtgtga cccgataagg tttcccatca attgtcaatt gggtataggt
    33781 atctgccgct acgtattgcg acaccttatc ggttagggaa cccaagtagc ggtctccaat
    33841 tttttcagca gtacttctat ctaggatagg aaccttactg gtgtcactcc taggaaattc
    33901 agtaaagtct ttttccgtaa ccgtgactac attggcataa tttttagcct gaaacatgct
    33961 ggaagttacc aaggaaacca aagctgccaa gagaagaatt cctccaatcg aagctaacag
    34021 aattttccct aaccgattga ttttgaaacc ctcaagattt aaggcagctt ccgccttacc
    34081 gtggcgcaca tgaaccgttt tgacaaggtt tatccccttg ccaaagccaa ataagattgc
    34141 cacaactaac aaatgcccac agaggaagaa gagaaattcc cagctggtca ggttaagggg
    34201 cggtaaaaag atataccagg tcgttgcgat aaaaataagt tcaaagacta ttcgtttcat
    34261 ttgctttcct cctaaatgat tcgtccttcc aagtgatcca gctcatgctg gcaaatctga
    34321 gctgggaagc ctgtcaaggt aatggtctgt tcctgccact tgctgtcacg ataggcaacc
    34381 cttatggttt cataacgctt agttgatctc acgcctacca aggacaaaca gccttcttct
    34441 gcctcatagg atccttcaaa ggacagaagc actgggttaa acatgaccac gggaaccaag
    34501 ccaagattaa agataatcac gcgcttctgc accccaatca tattggcagc tagaccaaca
    34561 caggtatcat gatttgctaa gagtgtatcc tgcaaatctc tggcaagata aaggtcctcc
    34621 tgacttgccg gctgagacac ttgagataaa aataagatat ccttcacaat tttcttttcc
    34681 acttcctcac actcctcttg ctttttacta tattatagca attatagcac aaaagccgat
    34741 aactgcaaac cctttccctc aactgtagca aaaagccatc cgaagatgac ttttttgcta
    34801 tttaatttct gtataagtta cttccaagcc acgcttaaca gctggacgat tggcaatttt
    34861 ttctgcccat tttactagat tttgataact tgaggcatcc aagaattttg cagaaccttg
    34921 gtaaagattt ccttgaacta actgtccata ccaagaccag atagcaatat ctgcaatcgt
    34981 atagtcattg cctgcaatat aaggtttctg agccaattcc ttatccaata aatccaactg
    35041 gcgtttcact tccattgtaa aacggttaat aggatattcc aatttttcag gagcataatt
    35101 gaagaaatgt ccaaatcccc cacctagaaa aggtgctgca cctgcttgcc agaatagcca
    35161 attcaaaact tctacctttt ccacaggatt acttggtaaa aaggctccaa atttctcagc
    35221 aaggtaaaga agaatatgag cagactcaaa gactcttaca tcttcagtac ctgactggtc
    35281 caataaggct ggaatcttgg aatttggatt gagcttcaca aagtctgatc cgaattgatc
    35341 cccatccatg atagcaatct tatacaagtc gtaagccgct tccttaaaac cagcttctag
    35401 taattcttcc aataagatag taaccttcac accatttggt gttcccagtg aataaagctg
    35461 aaaagcttgt tctccttttg gcaagttttg ttcgaaacgg gcacctactg ttggtctgtt
    35521 tagccccgta aaagctcctt gattactagc ttcatcctgc catacggtcg gtaattgata
    35581 tgctgacatc cgaaacctcc cttaaatcgc attcttgtca aaaccgagtt tgcgttgaat
    35641 aaacttaacg atttcgacga tgataatcat tgagaagctt ccagccataa caattcccca
    35701 ttgtgacaag tctagtttgg ttacgtggaa gattccttca agcggttcta caacgattgt
    35761 tgccatgaga aggataaagg ataccaagat ggaccagtta aaggtcttag acttgaatgg
    35821 gccaactgtc aagatggatt ggtagacaga cttgacattg taggcatgga agagctgaat
    35881 caaaccaagg gttgcaaagg ccatcgttag ggcatctgca tgaatagcat gattgtcacc
    35941 cacatgaact gggtaagcaa tcgcaaggcc ataaacactc ataacaagag ctgcttggag
    36001 tacaccttga taaatgatag aactcaaaac accacctgag aagaagcttg ccttgcgtcc
    36061 acgtggttta tgattcatga caccaggttc cgcaggttca acacctagtg caattgctgg
    36121 gaaggtatcc gttaccaagt taatccacaa aagatgaact ggctgcaaga cgtcccaacc
    36181 aaacaaggtt gataggaaga tggttaatac ttcagcagta ttggcagaaa gtaggtactg
    36241 aatagtcttt tgaatatttg agaagacctt acgtccttct tccactgcga cgataatagt
    36301 cgcaaagtta tcatctgcaa gaatcatatc agaagccccc ttagaaacct ctgtaccagt
    36361 gattcccata ccgataccga tgtctgctgt tttcagagct ggggcatcat tgacaccgtc
    36421 acctgtcatg gcaacgacct taccttgttt ttgccaagcc ttgacgatac gaaccttgtg
    36481 ctctggagac acacgggcat aaacagagta ttgaccaaca actttttcaa agtcttcatc
    36541 agataattcg ttgagctcag caccagttaa aacgtggtct tctgtatcgt ttgcgtcaat
    36601 gattcccaaa cgtttggcaa tagcttctgc ggtgtcttgg tggtcacctg taatcataat
    36661 tggacgaatt ccagcttcct tagccacacg aacagcctca gcagcttcag gacgttcagg
    36721 atcaatcatc ccaatcaaac cagtaaaaat taaatcattt tcaagctctt cagaagtgag
    36781 attttctgga atactatcga taatcttata agcacctgca aggacacgca aggcttgatg
    36841 agccatttca gaattgtttg tatgaatgag atttgtaacc ttctcatcaa tcggagcaat
    36901 atccccagcc ttatcacgaa gaagacaacg ttttaagagt tggtctggcg cacccttgac
    36961 tgctacaagg aaacgaccat ctggcaatgg gtgaactgtt gacatgagct tacggtcaga
    37021 gtcaaatggc aattcagcta cacgaggata tttctctaag aaacctttga catcatagcc
    37081 cttgtccaag gcatattgga taaaggctgt ttcggttggg tcaccaatca agttaccttc
    37141 cacatcgatt ttcgtatcat tggccaagac aactgaacga agtagtggca tttcaagacc
    37201 tagttcaata tcatcagctg agtcatgtag aaccgcatcg tagaagactt tttcgactgt
    37261 catcttgttc atagtcagcg taccagtctt atcagaagcg atgatttcag ttgaaccaag
    37321 tgtttcaact gctggcaact tacgaacgat ggaatgtcgt ttggccaaaa cttgagtacc
    37381 aagagaaaga acgatggtaa cgatagcagg aagtccttct ggaatggctg caacagcaag
    37441 ggcaacagaa gtcaacaact caccaagtgg atttttccct tgaatgaaga cacccactac
    37501 aaaagtaaca agggcaatga ccaagatagc ataggtcaag accttagaaa ggttgttcaa
    37561 gttttgtttg agtggtgtat cagtctcatc cgcatcttga agcataccag caatatgacc
    37621 aacttcagtg tacatacctg tattgacaac aacacccatc ccacgaccat aggttacgtt
    37681 tgagttttgg aaggccatgt tgacacggtc accaatacca gcatctgtcg caagctcgac
    37741 tgacaagtct ttttcgactg gtacagattc acccgtcaag gctgcttctt caattttaag
    37801 agagttggct tctagcaaac gtaggtccgc tggtaccacg tcacctgctt caagggcaac
    37861 gatatcgcct ggtaccaatt ctttagagtc aatctctgcc atgtgtccat cacgaagaac
    37921 gcgggcaact ggactagaca tggatttgag ggcttcaata gcttcttcag cttttccttc
    37981 ttggtaaaca ccaaaggcag cgttgatgat aaccacagct aggatgataa tggcatctgc
    38041 gatatcttcc ccaccagaag tcacgactga caagattgct gccgcaacta ggatgataat
    38101 catcaaatcc ttaaattgct cgatgaattt gaccaagatt gatcgtttct cgccttcttc
    38161 gagttcattg tgcccaaatt cggcaaggcg cttttccgcc tcacttgatg acaaaccttg
    38221 ctcggtcgca tccacagcct gcaagacctc ttcagggctc tgagtataaa acgcttggcg
    38281 tttttgttct tttgacatgt gtctcctcct tgacattgtg tgcaaaacag actctctttc
    38341 tgtcatatct tttcacgaca aacaaaaaga gacctgttaa tcataacaag tctcgctgtt
    38401 taagataggg ccggaaagca tacttttcag cataaaattc ggaatgacga cactatcaca
    38461 ggtttctgcc agctactccc ttgagtagta ccattatacc aaattttggg gagttttcaa
    38521 agagtaaaaa ctgccttatt tgaatttttc cttgaaaacc agtataatgg tagaatgcta
    38581 tgtgactaga aaggaagttg aatgaagcaa tctatctcaa atctcaagtt agctgagcgt
    38641 ggagccatta tcagtatttc gacctatttg atcttgtctg cagccaaatt agcagctggt
    38701 catctccttc attcatccag tttggtggcc gatggtttta ataacgtatc ggacatcatt
    38761 ggaaatgtgg ccctcttaat cgggattcgg atggcgcgcc agcctgcaga ccgtgaccac
    38821 cgttttggtc attggaagat tgaagatttg gcaagcttga tcacttctat catcatgttc
    38881 tatgtcggtt tcgatgttct aagagatacc attcaaaaga ttctcagtcg ggaagaaacg
    38941 gtcattgatc ctcttggtgc aactctagga atcatttctg cagcgattat gtttgtggtc
    39001 tatctctaca atactcgcct cagtaagaaa tccaactcca aggcgctgaa ggcagctgct
    39061 aaggacaatc tttctgacgc tgttacctca cttggaaccg ccattgccat cctagctagt
    39121 agtttcaatt atccgattgt ggataaactg gttgctatca tcatcacttt ctttatcttg
    39181 aagactgcct atgatatctt catcgagtct tcctttagtc tttcagatgg ctttgacgac
    39241 cgcctgctcg aggactacca aaaggctatc atggaaattc ccaaaatcag caaggtcaaa
    39301 tcgcaaagag gtcgcaccta cggtagcaac atctacctgg atattacact agagatgaat
    39361 cctgacttgt ctgtttttga aagccatgaa atcgcggatc aggtcgagtc tatgctggag
    39421 gagcgttttg gcgtctttga taccgatgtc catatcgaac cagcacctat ccctgaggat
    39481 gaaattttag acaatgtcta taaaaaattg cttatgcgtg aacaattgat tgaccaagga
    39541 aaccaactag aagaactctt gactgatgat tttgtctata ttcgccaaga tggagagcag
    39601 atggataaag aggcttataa gaccaaaaaa gagttaaatt ctgctatcaa ggacattcaa
    39661 attacttcca tcagtcaaaa aaccaaactc atctgctatg agttagatgg tatcatccat
    39721 accagtatct ggcgtcgcca cgaaacctgg caaaatatct ttcatcaaga aaccaaaaaa
    39781 gaatagagaa atcctttcat gagacgggat ttttctattc ttttatactc aataaaaatc
    39841 aaagtgcaaa ttaggaagcc ggtcacaggc tgtacttgag tcggcaatgt gaagccgaca
    39901 tagtttgcac tttgattttc gaatagtctt aactatcaaa ttcactgaga tactcatagc
    39961 gttcgtattt ttcaaggagt gcttcatttt tctcatccaa ttctttttgg agagtagcca
    40021 gcttaccaaa gtcagagccg ttagcctgca tttcctcttc aatagcagcg atacgttttt
    40081 ccaaggtttc aatatcacct tcaatacttg cccactcctg cttttcttgg taggtcatgc
    40141 gtttcttgtc ttctcgaacc ttgaccactt tttccttttc ggccttttgc acttgattgg
    40201 ccatatctgt ttcaaaagct ttttcatcaa gatagtcggt gtaatgacca aagaaaggac
    40261 gaatcttgcc atcctcaaaa gcgagaatct tggtcgctac cttatccaag aaatagcggt
    40321 cgtgactgac tgttaaaacg ggacctgcaa aaccttgcaa gaaattctcc aagactgtca
    40381 aagttgcaat atctaggtca ttggttggct cgtctaaaag aagaacattt ggtttttcca
    40441 aaagcagttt gaggagataa agacgttttt tctcaccccc tgacaatttc tcaatcaagg
    40501 ttccatgcgt cgaacgtggg aaaaggaact gctccagcaa ctctgcaatc gaagtcgtag
    40561 aaccaccact ggtcttgacc tcctctgcca cttcctgcag gtaattgata actctcttgc
    40621 tttcatccaa gccctcaatt tgctgagaga aataggcgat gcgaacagtt tccccaatca
    40681 caacttgtcc tttagttgac tcaagacttc ctgcaattaa gttgagtaag gttgattttc
    40741 caacaccgtt gtccccaacg attccgatac gatctttgac ctgtaccaag agattaaaat
    40801 cttgcaaaat gggcttgttt tcataggcaa aggaaacatc ctgaaactcg atgactttct
    40861 tcccaatccg actggtttca aagttcatag tcaagtctgt ctcagcacta ctgcctgaaa
    40921 cttccttttt cagatcatgg aaacgattga tacgagcttg ttgcttggtc gcacgtgcct
    40981 gcggttgtct gcgcatccag gccagttctt gtttgtagag ttgttctttt ttatgaagta
    41041 gagctgcatc gcgctcgtcc tgttctgcct taaggcgaac atagtcctgg taattgccct
    41101 gatattctgt caagcctgct cgctccaact cgaaaatccg tgttgacaaa gcgtctaaga
    41161 aataacgatc gtgagtgata aaaaggacgg tcttcttaga atttttcaaa aagagggtca
    41221 gccactcaat aatcgcaata tccagatggt tggtcggctc atccaaaagc aaaaggtcgt
    41281 ggttgccaag taagacttgt gccaactgta cccgtcttct cagaccacct gacaattccc
    41341 caacaggagt agataagtct tgaatgccca atttgctaag aacggtcttg acctgactct
    41401 cgatttccca agcttggaga gagtccatct ctgccatgac acgttccaaa cgcgcctgct
    41461 tgtcctcact atagtcgagc ataatcaatt catactcacg aatgagctgg atttccttga
    41521 gttcactaga tagaaccgta tccaaaactg tctttctatc atcaaaatca ggatcctgag
    41581 tcaagtaacc aatctggtaa tcatttttag ctgaaaaagg actgacatcc ccatcaaatc
    41641 cagaaacacc agaaaggacg tccaaaaggg tggtcttgcc agtcccattg acaccgatta
    41701 aaccaattct gtctaagtca tggataataa aggaaatatc cctaaaaacg gtcttgtcac
    41761 caacggattt acttagtttt tcaacgataa aatcactcat tttttctccc tcaggtaagc
    41821 atggatggct tcacgattat tctccaattc tccatcgaca atggcaaact caatctctgt
    41881 taaaatctct cccaagtctg ggcctggctg atagccatat tccttgatca aaatatcgcc
    41941 attaatctga atctctttct tgtcatggat agtcaagctt tggtattttt ctgtgatggc
    42001 ttgtaggttg acttcttttc cttgagcttg acgaagattt tcagcctgta aaagcaaatc
    42061 tatatcaaag cgataacaat ctcgcttgct caattctcca ttttcacgca gagccaaaat
    42121 aatcagcaaa tcctgaactt gcttggcaaa ctggcgtgag gtcttccaag atttcaaaaa
    42181 tgactgcgca ttttcaatct ccaaagccca tagtaaagcc gcccaggctt gttcagagga
    42241 ttcaaaagta aaatcagtct ccaaatcaaa cagtctgttg agcttgtcct ggctagatgc
    42301 catatcaggg agatagtcat aagcttgact ctcaatcatg gaagccaagc cccttctcca
    42361 aaatggagcc agcaagagtt tatcaaactc gacgaaggta cgctctacag aaattttctc
    42421 caaaagcggc gtcaaggtct tcatagcttt aaatgtttct ggctcaagtg caaaaccaag
    42481 actagcctga aaacggaaac cacgcataat ccgtaaagca tcttcgttga aacgctcact
    42541 agccactcca actgctcgca agacttgctt ttccaaatct tctaaaccat ggaacaagtc
    42601 aacgatttct cctgtctcat ccaaggcaaa ggcgttgact gtgaaatcac ggcgtttgag
    42661 gtcttcttct agcgagcgca caaaggaaac cgcactgggt ctgcgatagt ccacatagac
    42721 atcctctgtc cgaaaggttg ttacctcata ctcctcatcc ccatctaaga ccaagacggt
    42781 tccatgctcg attccgatat cggctgttcg cggaaaaatc tgcttggtct cttctggata
    42841 agaagacgtc gcaatatcca catcgtggat agggctatgg agaagggcat ctcgaacaga
    42901 gcccccaaca aaataagcct caaagcctgc ttctttaatt ttttctaata ctggtaaagc
    42961 cttctgaaat tcagaaggca tttgcgttaa tctcataata agtgttctaa tccatagaca
    43021 agctcatgac gcttgacaac ttctttaatt cccaaattga ctcctgtcat gaaggagatg
    43081 cgatcatagg agtcatgacg gagggtcaac ccttctccct gattgccaaa gatgacttcc
    43141 tgatgagcta ccaagcctgg caaacgaact gagtggatgc gcataccatc aaagtcagca
    43201 ccacgagcac cagcaatcag ctcttcctca tctgctgcac cttgctgaat tgactctcga
    43261 acctctgcca tcaactcagc tgttttaatg gctgttccac tcggagcatc ctttttcttg
    43321 tcatgatgga gctcaataat ctccacattt gggaaatatt tggcagcctg cgtcgcaaat
    43381 tgcatgagta agacagcacc caaggcaaag ttaggggcaa tcaggccacc caagtcttgg
    43441 gcacgagaaa attcttttag ctctgcaatt tcttcactcg tgaaaccagt cgttccaact
    43501 actggagcaa agccattttc aagagcaaaa cgtgtatttt cgtaggcaac agctggagta
    43561 gtaaaatcta tccagacatc cgcttcaaaa ccagctaaat cagccttatc cttgaaaaca
    43621 ggaataccct gccattctga ctcagactca aaaggatcca aaactgctac caagtccaag
    43681 tctggatcag tcaataccat ctgacaagca gcctggccca tctttccctt aaaaccggca
    43741 ataattactc gaatactcat ctctactcct gtccaagata caaagcctgt aagaacacaa
    43801 agtgaaaata ggaattctga tcaagaagtg tctacttctt ggaagaacta tctttttcac
    43861 acagggttcc aggcgtgttc aattatcaag atacaaagga ccttagctgc ccctgaaaaa
    43921 tagggaatgg cactgacttt ccacgaaagg caagacaggc atcttttttc aagaggcagg
    43981 tagtccgtgt tcaatttcta agattaacta gcctagaagt gccaactaaa tcactggaat
    44041 ataacctaga gcaatacttc ctgctcctag gtgcgttcca atgacactac caaatgtagc
    44101 aagtgaaaca tccgaaccca agccaaaatc aagcaaatgc tgacgcaatt cttcagcctt
    44161 ttcaggagca ttcccatgaa tgacaatgac ccggtattga cctgaagccg ttgtttcctt
    44221 gataatttca attaagcgtt tggtggcctt cttttcagta cgaacttttt cgtaaacttc
    44281 aatcacacct tgatcgttaa aataaaggat tggcttaatg ctaagcaaat tgcccaaaat
    44341 ggcagcccca tttgaaaggc gtccaccttt taccaaatga tccaagtcat ctaccatgat
    44401 aaaggctgac gtacggctga tttgaatggc tagcttatcc tgaatgctgg caaaatcatc
    44461 gccctgatca cgccaattaa agacgctttc aaccatgatg cctaggggag cacttgtaat
    44521 caaagtgtct gggaaagcaa tggttaagcc ctcatagtca tcgaccatat actggatatt
    44581 ttggtaaaaa cctgaaattc cagaagatag gaaaagcccc aaggcatgtg tataaccttg
    44641 ttctttgagc gaagttaaga tttcatctaa cttggcaata cttggttgac tggtcttagg
    44701 caattcagaa gcctgagcca ttttttggta aaattcctca gcagacagat tgatgccttc
    44761 gacatattcc tcaccatcaa tattgacagg aatatccaag acaaacaagt cttctctttg
    44821 caagatctct gcactgagat aagcagagga atctgtgaaa acagctaatt tcatattaga
    44881 actccaaatt aattcctggt aagtctaatg caatttcagt cacttcgtaa gtcaaacgat
    44941 tgagcatgtt caaacatgga cgagccaagg tttccacctc ttcttggttc aattcacttg
    45001 gttcattgac aatacggcca tcgatatggt ttacttgtga gattgttcca ctaatgacaa
    45061 acttatcaaa tacaatcata aagctcaaga tgacaatcaa ggaagtcact tgattttctt
    45121 ggtcatgttg gagcaattgg aaattcacat ccaccttggt ttcaggagct ccattttcat
    45181 tttcccattc aaaattacgt gcatcaaaat gatactgact aacaaattct tgttcacgtt
    45241 taagattcat gtctttctcc atcggctaca atattataag ctattgtacc ataatttttt
    45301 attttcatct agttttctag gatttagtca atcccaattt cagcacgaac tacatctgtg
    45361 atagtatcaa catagtagtc cacttcttct gttgtaggcg cttctgccat aacacgcaag
    45421 aggggctctg ttccacttgg acgaacaagg atacggccgt tccccgccat ttcttcttcc
    45481 atcttctcga tgatggcctt gatagctggc acttccatgg ccttttcctt catgacgttt
    45541 tccactcgga tattaactaa tttttgtgga taaatcgtta cttctgccgc caactctgat
    45601 aagctcttac cagtttcctt catgatttta gtcaattgaa ctgctgataa ttgaccatca
    45661 cctgtggtat tgtaatccat caagataacg tgaccagact gttcaccacc aaggttgtaa
    45721 cctgattttc tcatttcttc aacaacgtag cggtcaccaa ctgcagtaac tgccttgtta
    45781 ataccttcgc gattcaaggc cttgtggaaa ccaaggttag acataacagt tgtcacaatt
    45841 gtattttgag ccaattgtcc tttttcagaa aggtattttc cgatgatgta cataatcttg
    45901 tcaccatcga cgatgtcacc attctcatca acagcaatca agcggtcact gtctccatca
    45961 aaggccaaac caataactga cccactttct ttgaccactt cttgaagggc ttctggatgt
    46021 gttgaaccaa cattaaggtt gatgttaaga ccgtctggtg tttccccgat aaccgtcaat
    46081 tgggcaccaa ggtctgcaaa gatttgacgg gcactggtag aagctgctcc attagctgta
    46141 tccaaggcaa ccttcattcc atcaagagga gttccagttg aaacaaggta tccttcatac
    46201 ttacgcaagc cttctggata atctaccaaa attcctaagc cttctgcact tggacgagga
    46261 agagtgtctt cctcagcatc tagcaaggct tcaatttctg cttctttttc atcatctagt
    46321 ttgaagccat caccgccaaa gaacttgatt ccgttatcaa gggctgggtt gtggctagca
    46381 gaaatcatga caccggcact tgctccttca gtttcaacca agtaagctac tgctggtgtt
    46441 gcaaggacac caagtttgta tacgtgaatc cctactgaaa ggagacctgc caccaaggcc
    46501 gattccaaca tttcccctga aatacgtgtg tcacgtccta caaagacttt cggcgcttcc
    46561 gtttcatgtt gactaagaac atagcctcca aaacgtccta gtttaaaggc taattctggt
    46621 gttagttcta ggttagcttc tccacggact ccatcagtcc caaaatattt acccattgtt
    46681 ataaaatcct tttctatttt taattcgttt ttgaactagt tgctttcgtt gacgaagatg
    46741 tctccgatga actgcttgta cttgaatttg atgtgcttga acttggtgct actggttttg
    46801 tagtcacctt cattattgta tcaaacggag tgataactgc cggtaagaca acaccattgc
    46861 ggtcgattgc ctgcaaaggt actgaaccac tgtaattacc tgttatgcgt tcgctagttg
    46921 gcaagacagc gataatctta tcaattctat ccaatgtctc ttggtcactc gtaatagaca
    46981 cttctttatc tgacaccatg acattttcaa tttgtacccg actatcaatt tgactagggt
    47041 caatctctgg tacaatcttt accttatcct tctgagcctt cttaccaatc ttgactgtaa
    47101 ttttttgcgg agtcgccaca gcggtcagcc cattgggtaa atcttcaatg ctcaaaggaa
    47161 cttcaatcgt tccaacaccg gcatctgtta ggtcagcagt aaccttgaat ttacgtgtac
    47221 tttcttgcat ttcactagct agcgataggc gatttgcccc agtcaagacc actgatactt
    47281 ctgaagcaaa accgctaata aaatacttat cactattata gcgtatgtca atagggacat
    47341 ttgttactgt attagtatag gtttccgttt ttacctgcct agcactggta ctgttttgaa
    47401 aattcgtcgc cgtagcatag acaaataaga cacaagcaaa aaagagtgag gatatgatat
    47461 ataaactatt ttttttcatg tttccatcct cctagcaatc gttctttaaa actaagaccc
    47521 acttcctctt ttggaagtaa gatttcacgt aattctgttt caaattcatc aagtgttagg
    47581 ttgtgcttaa accttccatt ataggttatc gaaattcctc ccgtttcctc tgatacgaca
    47641 aaagtcaagg catctgagac ttctgataaa ccgatagccg cccggtgtct ggtcccaaat
    47701 tccttggaaa tccctgtgtt ttttgtcaag ggcagatagg cagacgtcac agcgatacgt
    47761 tcttctttga taatcaccgc accatcatgt aggggagtgt tgggaataaa aatgttaatg
    47821 agaagttctg cagaaatctt agcatccaag ggaattcctg tcgaaatata ctcctgcaag
    47881 gtacgtacac gctgaatagc aaccaaggcc ccgattttac gaggactcat gtattcaaca
    47941 gacttaacaa aggcacgaat catctgttcc tcagcactaa taggggcatt ggaaaaaaaa
    48001 tctgtcgctc ttcccaaacg ttccaaacca gtccgaatct ctggagagaa gataacaacc
    48061 gccgcaataa ccccataagt aataatttga ttgattaacc aagaaatcgt agtcaaacca
    48121 atcatatttg caaggatttg agctaaaata aacaccaaaa ctccacgtac caaaatcata
    48181 atcttggttc ctgcaatagc ttttgtaaaa tggtataaaa tataagcaac aatcaaaata
    48241 tcaatcagat tgatagctat cgtccatgga cttgcaaaca aactggtcca atattgcaga
    48301 ttggataatt gttgaaaatt catccctgat atcctcccta tcaaaacact ttcgtcctat
    48361 tataccattt tctggcattt ttttccctat cctagtccat tttacattga acaaaaatat
    48421 gataaaataa actgactaga aaaaacaaag gagaaactat gtctcaactc tatgatatta
    48481 ccattgtggg tggtggtcct gtcgggcttt ttgcagcctt ttatgcccac ctacgccaag
    48541 ccaaggttca aatcatcgac tctcttcccc agctaggtgg acaacctgct attctctacc
    48601 ctgaaaagga aatcctagac gtaccaggct tcccaaacct gactggagaa gagttgacta
    48661 accgcttgat tgaacagcta aatggatttg atacccctat tcatctcaat gaaacggttc
    48721 ttgagattga caaacaagaa gaagaatttg ccatcacaac ttctaaagga agtcacctga
    48781 ctaaaacagt tatcatcgct atgggtggcg gtgccttcaa accacgtccg ctggaacttg
    48841 aaggggttga gggctatgaa aatatccact accacgtttc taacattcag caatacgctg
    48901 gtaagaaagt gacgattctt ggtgggggag actcggctgt ggattgggct ttggcttttg
    48961 aaaaaatcgc accaactacc cttgttcacc gcagagataa tttccgtgcc ttggaacaca
    49021 gtgttcaagc cttgcaagaa tcatctgtaa ccatcaagac accattcgcc cctagccaac
    49081 tccttggaaa tggaaaaaca cttgataaac ttgaaatcac aaaagtcaaa tctgatgaaa
    49141 ctgaaaccat tgacctagac cacctctttg tcaactatgg tttcaaatct tctgtcggta
    49201 accttaaaaa ctgggggctc gacctcaacc gtcacaagat tatcgtcaac agcaaacagg
    49261 aatccagcca agcaggtatc tatgctatcg gtgactgctg ctactatgac ggaaaaattg
    49321 atctgattgc gacaggcctc ggagaagctc caactgctgt caacaacgct atcaactaca
    49381 ttgaccctga acaaaaagta caaccaaaac actctactag tttataaaaa agaaccacga
    49441 gtcacataga attcgtggtt ttataattca tccgcattta aaaatacctt tacatcgttt
    49501 tactatatct tacaatacct tttaaaacag ctatattttg agcttttaaa taaatgtttt
    49561 tacatcattt tacagagatt tacgacactt ttgccccttt tttgcccctt ttgagcaaac
    49621 aaaaaaaccg caagcctgag cctgcggtga aagaacaatt tagaaagttt cctttctatt
    49681 tatttaactg taatcaagcc atctggctct actgtgaact ctggcttgtc tgccatgcta
    49741 ccgtctggtt tgaggtagta ccagcctgtt ccgtccgctg actggataaa ggcatttgat
    49801 accatggcgc cttctttagc gtctaagtag taccaggtgt ccttgtactt gacccagcct
    49861 gtcttcatgg caccttctac atcaaaatag taccacttct cagcgatttt cttccagcct
    49921 gtagccattt cgcctgagtt gtcgaaccag taccaattac cgtctgtgtg cttcttccag
    49981 cggtctgaaa gcatatagcc tgagccatcg aaataatacc aggtaccgtt gattttctca
    50041 aacttatctt ttggataaaa gccgtctgag tgtacgtacc agtagccagt gccatttttc
    50101 tgccagcctg ttgcagcgct caagccgttt tcgatgtctt gcttaaactg ttcacggcta
    50161 atgccccaac ttgcaagata tggatatgga tccacatggt ctgagtggtt gtttggttgg
    50221 ttattggtac agtattcatg cgtcttgata cctgccaagt cgtctgtatc aagagtcttc
    50281 ggcaagcctg cttcgtccgc tagattgcgt agcaattcga tatagaggcg atagtcagcc
    50341 ataaactctt ccttagttga atggctttca atcagttcaa ccgctgcata actctcagca
    50401 ttccaaccgc ccccaacatc ccaacttccg ttgttcacag gacctacttg catgatgcga
    50461 ccgttcccaa caacgtgcga gaaaaaacct aattctgggt ctttccgcca gtgataatcc
    50521 gcttcatttt gagcggttga gttacggttg cctgttgagt gggcatgtac ttgtcgataa
    50581 ggctgcaccc caacctgggg caagcctgtt cgtagtctgc ttgtatcgat atccattact
    50641 cttgtccttt ccaagcgtcg ttcatctgtt tcactgctga ctctacgaag gtgtctaagt
    50701 ctttgtcagt catgctaata ttgtattttg taagctcagc acgaatttta gcgcgagcct
    50761 gtgccagttt ttcatctccc ttgtagccag tttcagcagc tacctgctcc acggcattta
    50821 ctgcattttt ggccaagatt tcaacaatct tgatggtctt ttctccacct ttttgaacca
    50881 ggtagtcctt gactgcccta actacaaccc ctgccaaaac gactaggatg ctgattgctc
    50941 cattagtaat gatttcagta atttgttgca tttgttattc tcctttttcg atttcttcca
    51001 tgcggtcgtt catgcgaacc atttcttttt gaatgtctcc gaccgcgtga gtgattgtgg
    51061 ttaattctgt agtggtcttt tctaggtgag tcatcaaacg ctcttctcgt ctattagagt
    51121 cggcctttga ttgctcgtgc aaatccataa tcttcttctc tcgcttgtcc gaagtcttga
    51181 taagatatcg aatgataata aagaaaagca agataaacaa aatcgcccaa gctacctgac
    51241 tttgagcgat tttttcagct tcttcaattg gcatacacac ctcctattct ttaggtttta
    51301 ccgttggatc cgtccagtca ggattgccct ctgcatcaaa tttcatgata tagaattcat
    51361 gattcaacag aacggctacg ttgattgttg cgattgtacc accccactgg ttgaacgccc
    51421 aaacggtttc aacatccttt aattggcgac ggccatttac gatcacagga cgtttttgaa
    51481 catcacgata catatagaag tcatcgctta cattcttgca acgaatgaac tctccatttt
    51541 ctttcatgta gcgcaaagcg ctcgcaagat caaatggttc tgtgattttt gtaaggtcta
    51601 gtaagttatc tgtgttttga attgtttctg ccatgtctat tctcctttgt ctgctggttt
    51661 agtttgttca tcaagcagag cttccagctc atccactcgt gcttgaagtc tttgattctc
    51721 ttccctttgc tcattcaact gaatactcaa gatattactt gtaatcatcg aatttgttga
    51781 agttgttgac atttcactaa ttgtcatttg taaggcttgg ttaagctgtt ctgtgttcat
    51841 tttctaagtt ctccaatctg tgtgttcgtt ttctattttc aagagcaagc tcttaaattg
    51901 ctttaagtgc gatattggtc aacatgttgt tattcatgct attgttttct ccattttttc
    51961 tattttttga tttaattctt gaatagcctt gattaagtaa ggaactaaag cggtatagtc
    52021 gatatgtaga tagccatctg gattctcagg atctcgtgag acaattcttg gaacgatggt
    52081 ttcagcctct tgagctatta gaccaatctc ctcatgtttc ttactttcga tgaaatcaaa
    52141 tgcaaccatt cttaatctgt tgattttatc caaggctttc acagctgtat ctgtgatgtt
    52201 ctcttttaag cgtctgtctg atttttgttc catccaatac ttcacgctac cgctaccgac
    52261 ctgattccac caaacaaccg cattccttcc gcctttggga ttccaaccat caccaagcac
    52321 atctttactt ccaagttcga taccatttga aaacacagga gaacgagaaa aagtagtatt
    52381 cccatagaag tttgctctcg atgaattcga aaaatccact tgatcataaa aaccgacttc
    52441 attcctacag tacattttcc catcagtatt gacgttccat gctttaggtc cggcatagtt
    52501 ccaattattt ccccagttcg cccagaaggc tgtccggact ccatgcccgg caccattccc
    52561 cataccaaca gagaactgat tgacacctga aatccagcga ccgccaccct ggtcaaattg
    52621 accaagtgtg aatccaccaa ttcgaccttg ataggcttct aggaaggttg aactagaaat
    52681 gacggactca accttagtag agaagatacg tttagatgtc agttggtcaa taaaagcatc
    52741 atttgcagtt aattttttaa taagcgcatt gtcaactttc aacttctcag cagttaccgc
    52801 ttcagcttct aatatcgtag tcgtgaccga accagcttca aaattgcccg ttttcaactt
    52861 atcaaccatg gcagacttga tgactgctct gtcaatcagg gtctctccag tgatgtgggt
    52921 caatttccca acaaagcggt tatgtccatt ggcgccaaga ttgattccag agatgatatc
    52981 tccagccgag ttgatgtttt gaactgccca tgagccagtt agtagagtca tttttgtttg
    53041 cgtggcttca agcttcttat tcgcatctgc gaccacatct tctggatgtg gttgccatgt
    53101 tctaggttta taacctttgt acaagtcaac ttctgtaata tacaaatcag ctgttcctga
    53161 tgatgagcca ttgttatcaa aacgaatgta agcattatcc atttctccgg aattaaaagt
    53221 tactgagaca tcttcgcatc tagaggtaga tagtttcttg ctgctaacaa ctttcttaac
    53281 gattgtgaat ccatcgctct cgcctgctct tcgtcccaaa atataaacat catagcttgc
    53341 gagagcactg ttgttaaatc ctctaaaatt cagtacatag tcagtatttc gttcaagatt
    53401 aaaacggtga ctatacaaaa agttttcgtt tttagttgca ttacttaaac gcataaggtc
    53461 tttctgcccg ttgtgataaa agctatgctt aaccaatctt cctaaatttt gagttgagcc
    53521 ccattcattc gtagcatttt taaaatcact attcttaatg aggttagggc cgcttacact
    53581 atatttccca acctcaacct gaaacagttg attggtcaga gccatgcgag caaccttatc
    53641 cgcaattcca ttttcagtat tgcccaaaat ccgctcgtaa agtttactgg tttccttaac
    53701 acgctggaag tcagtagtct ctacttttcg cgctagttga ttggtcacat tcgcaaattg
    53761 actatcagca ttcgctttgt ttgcagaaac ctgatcagat attctaccca tttgtcgttc
    53821 agcattatcc ttgtttgtag cgacctgagt ctttaaattt gaaatctgat tatctgtgcc
    53881 ttgtttatta ctgtttatcc gatttgaaat atttgaaatc tgagtagtgg ctccttgctc
    53941 actgcttgta agtctatttg atagaccact gatttgaccg cccacatctt gcttataagt
    54001 agttatctga cttgaaatat ccgtgaactt accatctaca gattgacgat agctagcgat
    54061 ttgactagcg atgtctttat tcgcactagt tttaacagct tcaatcctct gattgatacc
    54121 cttaacatct tcttgataag taaccttacc aacgaaatca cgattgacca gctcacggac
    54181 tgctgtcgct tgtctcgtgc tctcctcacg agtatagcgc tgtagggctt cctgtcgctg
    54241 accgttttta tttacatatt cctgaatagc tgataaatcg gttcgcaagc cctgagctgt
    54301 ccgctcaaag gtagccttag cttcagtgat gagaccatca gcgtcctcag gcgcaggact
    54361 ccagtccgtc gccacactac cgatttcaac cttgattcct gttacccaag ctgtaccgct
    54421 tgtagcacct tcaagattga atcgcaatga tgtcttcaat tgatcaaaat ttgttttttc
    54481 agagtagtca taagtgaatg taatatattt ccaatctgcc gaacctttat acataccaag
    54541 cgtagcataa tctggaccac tctgtactcc ggtctcacta ttttttctaa aaagataatg
    54601 tttgaagcaa ttaaatacat tccaaaaatt tcgaccttgg actacatttt cgtacttgat
    54661 ccaagcgcta aaagtaactt tttggtacaa ccttgagctg aaatctggtt caaggttgaa
    54721 cgttaaagta gagttgttct ctagcctata gcattctttt tgacctgtga cgtggttttc
    54781 aggtaatttt tcaattacag ctccaaccgt cttggatttt atccatagat tccggcctcc
    54841 caccttcatt tttgaaaatt cttcacgcaa tttcccagct tcagatacaa ctaaagtctt
    54901 atctgcttta tccttggttg cgttcaggat ttcctgacgg atagagccag ctcgcacctc
    54961 aaattcagcc tgactcaact tctgatttag tttgttctgc gtgtctgtct caagactctt
    55021 cacagattgc cggatatttt cagcagtcac attgagtgag ctgatatcgg ctttggttct
    55081 aaggccttca gtcagacggc ttacaccagc gtcgagtgag ttggctcgtt gtttgaaggt
    55141 cgattcaact gttgaaatct gaccttctat atcttcagga gcttctgaat aagaagtatc
    55201 tacatcgctt atttcaaact tcggcatcca aatccaaacg gttccttcct ggttgaaatt
    55261 gaacaaccat tcatttgtgg tctgcttgga ttcgtttgtc caaccttttg gaatatggac
    55321 aacatatcgt ttaatttctg tcgacaatgt cacatttcca gttttatatc cgatattccc
    55381 taatcgagat cttagcatta ttccattttt atttgcctta gcataaaaac taatggttac
    55441 atcttgatta gtcgtacttc cgggaattac tttcccgaat tgacccagag ctgggtaagt
    55501 aaccttggga ttccctccat cacggccaga tggattcaga cctataattt taagagcctt
    55561 atgtccaaga tacttacttt cgctatcgat agcagccgta tatgtactcg ttgtccaaat
    55621 tcctgttttt gaaatatcct gcttgaatag tgagttcaag aatagatttc gaccggatgc
    55681 ctgcacactc gcaatccgac tagccagctc ctcagctgtc tgcgtgagtt ctgacttgct
    55741 ggctttatcc ttggttgcgt tcaggatttc ctgatggata gagccagctc gcacctcaaa
    55801 ttcagcctga ctcaacttct gatttagctt gttctgcgtg tctgtctcaa gactcttcac
    55861 agattgccgg atattctcag cagtcacatt gagtgagctg atatccgctt tagttctaag
    55921 cccttcagtc agacggctta caccagcttc gagcgagttg gcacgctgtt tgaaggtcga
    55981 ttcaactgtt gaaatctgac cttctatatc ttcaggagct tcttttgagc ttgttgccaa
    56041 acttccgtct tccagctggg gcgcaagaac atctaaatat tctccgacct cagcatttac
    56101 gagatacaca tagccaattg atgcgactcc agccctattt ctagcgctag taaacgatag
    56161 ctttgtccaa ttttcatcct ttaatgtaaa gatgggcgaa atacccgaat tatcattgac
    56221 ttgccaataa gtttgtagct tgaccttttg acctcttctg cctttgaccc aacaagacat
    56281 cgtgtatgtg ccttgcgaga tataaaatcc atcttgagca atacctattt ggtctctagc
    56341 attgcttgag gtcaatcgta tcgctttatc aaagccagtt gctggactgt ctgatacatc
    56401 aatcgtcttt gccgtcccag cgcctgacgg tctaaaagta cctgatgccc acaatcctct
    56461 ggctagcatc atgcgctttg taccccggat ataattccta cccccgacct gcacactcgc
    56521 tatccgacta gccagctcct cagctgtttg cgtgagttct gacttgctgg ctttaccatt
    56581 ggccaagttg gtcagttctg aaagtctacg agtcgtcgtc tcctcatacg tcgcttgcgc
    56641 tgacttcacg ccagccagtt catttttagt ccggctaagt gcttcaactt gcttggcaat
    56701 ctcagcttca gcctgtgctt gcttcggtcg aatatcgttt gcgatagttc gttttagaac
    56761 atccaagtca cctgacaaag ccgtctgagc gctcgtagtc tgcgacttaa acgcttcaag
    56821 tctagcgaca gaatccagct caatccgctt agcttcctga gcgagtaagc tacttgcgcc
    56881 agccagttca tttttagtcc ggctaagtgc ttcaacttgc ttggcaatct cagcttcagc
    56941 ctgtgcttgc ttcggtcgaa tatcattcgc gatagtccgt ttcagagcgt ccaagtcacc
    57001 cgacagagcc gtttgtgcgc tcgtagtctg cgacttaaac gcttcaagtc tagcgacaga
    57061 atccagtcca atccgcttag cttcctgtgc aagcagggta cttgcgccag catttcgcaa
    57121 agcttcctca gccttgcgct tagtttcttt caatggcccg ttgtcaaagc tattaaatcg
    57181 ctgattgata gtgtcagaca gttctctctt gacttcttcc gccttggcct tggcaagttc
    57241 tacttgatcg ttaaagtctt ttttgatttt gtcgaccttt tggtcaaaat ctttatctgt
    57301 tgcttcaatc tgcgcttgga ttttcgcttc aatgccacct tgttgcttaa tatgcttggt
    57361 aatcgtaccc tcgtaagaat actgagtatc gtttccagcc ttactatctg cgctgatacg
    57421 ccctctcaga ccacctttaa aagtaaagct ctgacttaac acaggaactt taaaggtctc
    57481 tttcttattg gtctgaatgg ttacccactg cccgacctca agcagtaaat gcccttggta
    57541 gttgagatta tacggatagt aagttaggtt tttcagtttg taatacaggt catttaaagc
    57601 gctctgggtc atgaagacat tgtccagttc caaagaccgg cccgtcttca taccgaccgt
    57661 cagagacttc ttgtccgtct tacaagtgat accagctatc tgatactcaa tctcactctt
    57721 ggtcaagcca tgcaagaagt aactgtcagc gttgatcgtg atattggact cagtcaaatc
    57781 acggatttcc atcttgcctt ctctgttgaa gaaacaagac atcccaatca tctgagtcat
    57841 agcgctcagc atatccctaa aggaaagttt cttgccctca ggaacttgct caatatgata
    57901 acgcatcgcg ctgattccga aatagtcatt cgctaactca atgcctgttt tcaggcagat
    57961 ttcctgaata acctctcgta cttcagctgg gaaatgcaag tccgtcacgt actcacgatt
    58021 gagcttaaac ataccgtcca taagttcaag cgtggtagtg tttcggtttc ggtcaatctc
    58081 aatatcgttg atgaagtatt cccccatctt gacccactgg taggtatccc caaccagtag
    58141 accaatctca gggtgcaggg tatccagctt attgaacgtg gtaatgatac tggtaaaggt
    58201 aattttaccg ctaccagcgc aggttccacc aggcttataa gtatcgccct tgatgtagcc
    58261 atactcaaaa ctagcctctt tgatatcccg tgaagcatat tcaccaacac gaatagccag
    58321 cgtcctttcc ttggcaaaca tagatctgtc aaattgtcgt ctagttaaag cgtccatttt
    58381 cttacctctc taccagatta aatttagcgc cagaccaagg tttaaacttc tcagtaaagg
    58441 tatagctagg agctgtccta gcaccgacat agaaagtctt tgtgacttgg ccatccatgg
    58501 ggtctggata agatacctca aaaaattcag atgatacagc atgtaaaagc tgacttattt
    58561 ctccctgagt catcataccc cattcacagt ctagtttgcg tttggtcgtg atacggtcac
    58621 gcaccatgtc gccattggca ttacgccctg tctctccatc gatatcttga ataccgactt
    58681 gaaaagattt gggaggcttc acagccaccc cattgattgt caattgtgcc atttaacctc
    58741 ctaaatcttg agcaaggttt gacctgctcg ttcatgttcc ttgttgattt cttggatagc
    58801 tacccgtccg aactcatggc ctgcgatttg gataacgatg tcgccagccg gtaatgaata
    58861 acctgtaggt acattattag caggcattct ttcagccagt ttttgagcca agatagaaat
    58921 ccatcctgta ttccgttcaa gaggcattac cgcttcttga ccagcttctc cgaccccaat
    58981 gatgctagga gagttgaata caccgcctcg tgcataccaa tctacagaga atgatggaat
    59041 tctaggaggc atcaagctga agctaccaga tatattaaag tgagggagtt tgatttttgg
    59101 taagctccaa tcaaagttaa agaagctttt tagtttatcg ataccacttt taacgatgtt
    59161 tttagcatta tccattgcat cattaaacag attcttgaac cagttgggga tttctttcaa
    59221 ggcatcttgc atatctttcc atctatcacc aaaccaagaa ccgatttttt ggaaaggatt
    59281 ctgagttttc ttttttgcac tctcaaattt ctctccaaac catgtatcag cttctttcac
    59341 tccatctttg atatcattcc aacggtcacc gaaccaagag ccaacttttt caaaagctga
    59401 gttcacttta tcccgacctg acttgaactt atcaccaagc caagtatttg cttcggcaag
    59461 tgcgttttta gaatcattcc aacggccacc aaaccaagag cctaagttgc caaatatatt
    59521 tccaatagcg tcccatgctt gctggaattt ctcgccaaac cattgaccta tcggctcaaa
    59581 gatttcttgt agtttcgtcc atagaccgct gaaaaattcg ccaatcgctt gacaaatacc
    59641 actgataaaa tcacatagtc cttgccatgc agttttagca aactcaacaa cagtgtccca
    59701 attttggtag agcaaaacac cgatagcaat taaggctgcg attgctgcaa taatccatgt
    59761 tattggactt gtcaaaactg ctaacgctgc attaaaagcc catgttgcag ctgtagcgac
    59821 tcctgctgca acagaatgtg caaattccgc cgcggttgct aatcccattt tcgctgcatg
    59881 agcagtccat gctagagctg atttaccaag ttctaaagca gtttttccta gctgtgcaat
    59941 tgttttacct gaattgacca caaaatcttt tgcatataag gtgttcaaat agattgtttc
    60001 agcaaaactg accaacttat caaatgtcaa tgctttaata gcaagaccta gattcttaat
    60061 tcctccaaca atcaaagaga ccttactacc taacaagctg aatgctcctg caagtcctcc
    60121 agcttgttct gcccatgata agaaattaat cgtttgccaa gttgttatca aagctacgat
    60181 aggttctttg ttttctttac accagtcaga aaaaacggtg aaaccatctg ccactaactt
    60241 aatagcatac gccaatagtc ccaaagtggc taaaaggcca cctcctaata aatctgaaat
    60301 tccttcaata ctaacaccga atactcctga taaaaactca gcaaaaggtt gccaggaatt
    60361 ctcccagaga atctgaataa tgtcaattag cccattaaaa gcattagcaa tagagttaat
    60421 agcagggact acatgttcat cataaacacg acttaagcca tcgccaaatt tgttaacaga
    60481 cctttcaatg ctctcaaata caggcgcaac agtatctaat aaactttgga agactgatga
    60541 aattttagga gcgcttgtca caacgacttt ttcaaaacct ttaaacaaac ttcctgctaa
    60601 tttactacca acttcaacaa tggtagatgt caaactcaac agagttgaca caatagcgct
    60661 accgatacga accgcaccag ttgaggtaat gacgtcgtag aaagcactag aaaagtcctg
    60721 agctatgttt cctactgcct cggaaaggtt accaacatta tcaaacaaag cgactagcgc
    60781 cctggtaatg cgttcttttt gccttccaag gccatttgca atactttcgg caaggaaaac
    60841 accgatacct agcccgatag tagctattga gcctgtcact tgccctaaag cataagcaat
    60901 tttctcagcc attcggttaa aggcattcac aacccttggg tcagtggcga tttctcccat
    60961 tgtcttagct atttggtcta aggcagtctt aatgcgtttt ataccttctg gtctaaatgc
    61021 tgcatcaaaa cctttcttga agaggtcaaa caaccctttg agcttatctc caagaccatc
    61081 aaaaatgctc ttgaatttgt tgtccatgtc agtcaactcg acttctggca agatgtcttt
    61141 gaaaggtccg ccaccgcctc cctttccttt accacctttg ccaccgcctc cagaaccgcc
    61201 tgcgtcgtca tcttttggtt tttgcaagat gttaatctca tcaaatccca aaagacctag
    61261 caactcttta gcagctttct tagcgttttt ggctgagtct ccaagattgt cagcaagtcc
    61321 tcctgctgaa tctccagcgt cgtctactgc gtcagcaagg tctcctgctc cgcctgcagc
    61381 atccttcatg gcgttaccca tgtctccaac tgctccacca acaccatctt tcactgttgc
    61441 tttcttgttg aacatcaaag caataaactc agcgagttta gcagtaacgt tcttcaaaac
    61501 catagcaaaa gagttcaaga caggcataat ggcattgata atcggtaaca tagagttacc
    61561 aaggttcaat gctgcgtcct tcatcagcga cttaaatagg ctgatacgac catttacaga
    61621 attagacaag gtattcccat acttggctgt agcctgttcc agaatagcca taaggcggat
    61681 ttgttgctgg gtttggtagt ctaattgttg ccagctttgt ccgtttgcga acttcttaaa
    61741 agcttcagtg gacttaatca tagccacatt gacgttgatt cctaggtcct caattgcttc
    61801 ggtgttccct agtagacctg agcgaatccg ctccataacg tctgtaatcg tgcgccctga
    61861 accttcagca accactgccg atgtctgcaa catcttagca gtataggcgc ttagcttgtt
    61921 ggtatctttg ataaatccag aaaataagtt tgaatagact gcaccgtagt tggtcgcctc
    61981 acccactccc atattcatag cgttggcgtt atcgttaacc catttcaaga aagattgcga
    62041 actctcgccc atctgtcgct tgatttggtt catagacgct gacacttcaa gagctgtctg
    62101 cgttgaatac attccaacat caagtaattt cttaccaagg attgcaaaac cagcaaactt
    62161 agccagctta ccaaacgcac taccgattga gttcgactgt tcacgaactt tggcagtggc
    62221 atttttcact tggtcagatg ttcctttgac ctgattctcg acttctttca tctttttcct
    62281 gaaaggcgct atctcagcgt caatcatgac cttcaattca tcaagagttg ccatttactt
    62341 cctccttcct ttttcgatta tgtctctctg caaaatcacg catccgttcc ttatgcaaca
    62401 aaagcgcttg tctctgtcgt tcctgttcta ctgcttgctg ttcttctaca aacaactcag
    62461 gcgcatattc ccaaagctca acaatcttag cgtcattgga cagtaataag gaaacatgat
    62521 tagttatcat tcgcgaaagt atgtacgagt caataatctt ttctttacgc tcttggattt
    62581 tgacacggtt gtagctttct atcatttccc tgatttcaag caccgttaaa tcccaaaaat
    62641 caagaggctt gcccccgatg tctaaaaaca taggataaag cctctcaata atctgcgtta
    62701 ccgttaagat tactcgacta ctgtcatttt cttcttggaa gttttcttgt ccttgcttcc
    62761 tcgtggagta aaacccgata cttcaaatag cggcatcaac acctctgtca tgaatgtcgt
    62821 ttggtctccg ccgttatcca cgtattcatc gtataggtcg tagacatctt caaaggaata
    62881 cccatgttca tactgctgca aggctccatg aactaacaac agcataactt tcaaaggcgg
    62941 taaagtgaac tcttcgccag cttcaggcat gaaaatcttt aacaagttca tgccgatttt
    63001 ttcttccaca gttgcagctt gatgagatgt caaacgtagc ttcaactctt tttcgtcagt
    63061 aactttccaa gttgtgtatt ttaacgccat ttaattaacc tccaattcca tcaacgaatg
    63121 tcaattcaga ctgcaatgca atcttaagtg tgaactcgat aacggcatta acgccgccac
    63181 cgcccagttt aacggatact tgaccttcaa aagtgacctt agtaccgtct gggtaggttt
    63241 gttcaaagta gagttttttc ttgccatctg ctgccttacg taatacacgg taaggagctg
    63301 ttgcgcttga attattataa gcgaacttgt actcaagttc tcctgcgtcc ccgataccaa
    63361 actcgtactt cttcaccgta tctgcaagag tagtattttc tactttttcg ggctcgatac
    63421 caaattcagg tacttcctta agccctacaa gattctgata attgcctttc gtttcactaa
    63481 aggccaattt aattccattt gctaacatgt ttaattctcc attctaaatt gaaaaacaag
    63541 ctctgagtct aaatcaacga caccttcaaa acgcatgacc ttatgtctca aatgagacgg
    63601 gtctggcacg tcttggcagt cagttcttcg caaacctaaa gactcaaaaa tctgattgat
    63661 tttaacagct aactcactag tgctggtatc atcaaagata tccaccttat agcggataga
    63721 tgatttttgt tcctggtcat caaaccaatc acccggcttg ttttgttctt ctaaaaaaat
    63781 aacgactggg aaagtctccc aatcgctagg ataagtatcg gtcacattat ctgcaacctt
    63841 ttgcaattct ttataaataa caggcttgat attaatcatt ttatttgttc tcttatcttt
    63901 ctacggacat aattcgaaat attcttagac acacgctctt gattgtctct caaagctgga
    63961 taaagataag gctgggcagg ttgaccatac atcttgtaga actccccaat cttttgaaag
    64021 tggtacggtc ctacatttat ttggtcttca tgcacatacc aaggattaga cttgtaagtc
    64081 acgctgacct ctggagagat acccgaatgg ttagcttgtc ctattggtcc tgttccaaac
    64141 tcaacgtaag gagcgtattt aaggttggtg taaacttcgc ctatagcctt atctccgtcc
    64201 atttttgctc tagttttgat actaattata agctctccat ctctcgctgg tgcgagtctt
    64261 cttgcatctg cttggacaac ctttatagta gcattgtgta ccgcacgtaa gacgatatcc
    64321 tcgccagttt ttttactagc caatcgtcta catttagcta taagcctatc tgcccctagt
    64381 agccctgaca cgctctaact ccaaaacttg atgatgtgtg tagacctttt tagaaataac
    64441 cctgtgagtc acttctgtct ggctatcgat acacacacca tctttcactt tgatagtagc
    64501 tgacttgttg gcatttgcgt tcaaaatatc attgacacgc tcgccataca attcagattg
    64561 taacttgcta ctagctggcc acaattcaag gcggactgtc tcagcttcct tggcataccc
    64621 ttctttcgcg acaccttcct cagtgacagt cttttcaaac cgtcgcattg gataaggttt
    64681 cagtctactc tgcttcaaaa acatgacctg ccacccttgc tagcctgtgc atgcgtattc
    64741 gctgtagaag acccgtagac aggccatttt ctccgtagac tactgctata ccaccttcgg
    64801 ttctagaacg ctctccttcc gctcctgagc ggttgtggag ctcgatagca acctcaggta
    64861 ttaaaagact taaagcaggt gtcaaagatg tgcgattagt ctctgacaag ataagatttg
    64921 tagcccttgt ttggaacaac atgagaagct gagtatcttc ttcgcctgtt aatttcttca
    64981 gcaactctat agacatatca atcctcttct aagaactcag gttcagggag gattttctca
    65041 agaacatctg agatagcgac accgttgctg gcaatattgt cagccagctc agcatagcgc
    65101 tcctcagtaa tctcaagttc ctctcctgcc agtcgtttca catttgattc ccaatcatag
    65161 aaatcttgtt tgattttaaa tttcataact aagacctatt tcttaccagt tttttctttc
    65221 cagttagctg agtcagagcc tggtgcattg gttgagctag tgatgtcttt gatagcaaca
    65281 tagactttat cttcatgcgt tactgtatca ccttctttat aggctgttcc agtcttccac
    65341 gctttagcac ggttcactgt cttgccttgg gctgattttt tagcagcagg cttagaatct
    65401 gcaattgtga tgatgtattt tttgaagtgt tcaagcacaa atgcaccagt gtaaagtaat
    65461 tgctctacca attcaccaaa tcgacctgga atgttatcgt tgtacttagt attgtctact
    65521 tgtactggag atgtaacaac acctggagca gtagcaaggg cattaacacc tttcaagaat
    65581 ttagaaggaa ctttatagac tgtgtaatca tccaattcac caacatatcc ttttccaagg
    65641 actttcttat ctgcgtcacc atgtggtaga cgaacgattt cagacttgat cgctttgtag
    65701 aatttaggtg ttacaaaaag caagcgctct tttgtaattc caagctcatc aagtttctca
    65761 gaaacatcaa gaattgcgtt gtatgcgttg ttcgctcctg cttctttgcc catagtaacg
    65821 ttgtcgctaa cattaccaag cgctgcacta aaacgtagtt catcaagata tggagctact
    65881 acttctgccg cttgacgggc aataacataa ttgatattca cttgaccatt agagtcacgt
    65941 tcgtccaatt gatctacgaa acgaccccag tatttttctt catcaagggt ataaaccttt
    66001 tcttcaactt caacgtgatc aaattcgttg tctttgttac gtttgtagtc tttcaactct
    66061 gttgtgttac cagttgctac tgtaaaagag cgaccttgca aggttactgc atcgcttgat
    66121 gtcacaagtg gtgttgaata tgaatttact gcaagtacat cctcaataat cccaagatgt
    66181 ttcttgcgtg attctgctgt gtttaattct tcaaatgcca tttatttttc ctcttttctt
    66241 ttattacaag aagtctttac gccatttttc cgtgacttct tgctggactg tttgtgcatt
    66301 tttgataggt gcactacctt tcatacgttc agagactccc ttctgaactg actcttccca
    66361 tgctttttgg atagaggtga tagattcaga taccgtctct gcgtttgtca aatcgactac
    66421 atttactaac tcaacaggta agtcacgttc acttagcatt gctttagcct ctgcggtcaa
    66481 ttccttacga gcaatagcct tttcacggtc agctagttct tgctcacgct gatccaactg
    66541 atatttctgt ttttcatcag cgttcatctt agcaagcttc ttagcttcgt tttccttggc
    66601 ttcttgctca gcttcccatt tagagcgctc ggcagatagc atcttaccga tttcagcacg
    66661 agtgaaagtt cgttcgtgct tttcttcctg cactgaatca acatttcctt gagtgtcgac
    66721 agtctcagtt gattcagtag atacagttgc attgatttct tctgacataa ttgtcctcca
    66781 gcgattacgt cgccactcga taatctcgct ttacgtccgg cgacggaaca gtgcagcttt
    66841 taatgtcatc ggcacagttt ggacaatata aaaaccgtac gggattccat acggttagat
    66901 tattttgtat tttcttcaat cacttttttt acaaatgcta tgataatcag catcaaaaac
    66961 aaaaatacca accacccgaa agcgattgat acccaatccc atataaacat atcttactcc
    67021 ttttaatgtc acaatcaatc aacttcatac gataatgaat gaatgtcggt taatatttta
    67081 ggtagtaact caatcgcgct gaacgtatcc gccccataaa tatttaactc taatttcact
    67141 gtcgctgatt caattccgcc tgttcctgaa aattctacgt tagttatccc aatttttgct
    67201 ttatccattt tcaatccttt ctgggtacga aaaaagcact tagatttctc taggtgctta
    67261 agtaata
//
LOCUS       DBEROT010000006        65384 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.06, whole genome shotgun sequence.
ACCESSION   DBEROT010000006 DBEROT010000000
VERSION     DBEROT010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 65384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65384
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.06"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..229
                     /locus_tag="ACL8CG_000454"
     CDS             <1..229
                     /locus_tag="ACL8CG_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343114.1"
                     /translation="DSTGGGKRLSTSIRSAYSGSDITPVYSLGSGSRIVMYYNGGGDN
                     YIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            325..1089
                     /locus_tag="ACL8CG_000455"
     CDS             325..1089
                     /locus_tag="ACL8CG_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343115.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVATLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVTYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            1089..1841
                     /locus_tag="ACL8CG_000456"
     CDS             1089..1841
                     /locus_tag="ACL8CG_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343116.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLGEFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            1851..2549
                     /locus_tag="ACL8CG_000457"
     CDS             1851..2549
                     /locus_tag="ACL8CG_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343117.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            2546..3193
                     /locus_tag="ACL8CG_000458"
     CDS             2546..3193
                     /locus_tag="ACL8CG_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343118.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRELSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(3273..3905)
                     /locus_tag="ACL8CG_000459"
     CDS             complement(3273..3905)
                     /locus_tag="ACL8CG_000459"
                     /inference="COORDINATES: protein motif:HMM:NF012707.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS1343119.1"
                     /translation="MELGNQLAQDLGVKVKYISVDAANRAEYLISNKVDITLANFTVT
                     DERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLIVTKGTTAETYFEKNHPEI
                     KLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGFEVGITSLGDPDTIAAAVQ
                     KDNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAKADDLVVEGGH"
     gene            complement(3896..4138)
                     /locus_tag="ACL8CG_000460"
     CDS             complement(3896..4138)
                     /locus_tag="ACL8CG_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HGS1343120.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYATILN"
     gene            complement(4150..4907)
                     /locus_tag="ACL8CG_000461"
                     /pseudo
     CDS             complement(4150..4907)
                     /locus_tag="ACL8CG_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(4908..5585)
                     /locus_tag="ACL8CG_000462"
                     /pseudo
     CDS             complement(4908..5585)
                     /locus_tag="ACL8CG_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
     gene            complement(5545..6225)
                     /locus_tag="ACL8CG_000463"
     CDS             complement(5545..6225)
                     /locus_tag="ACL8CG_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1343121.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            6440..6574
                     /locus_tag="ACL8CG_000464"
                     /pseudo
     CDS             6440..6574
                     /locus_tag="ACL8CG_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            6714..8204
                     /gene="lysS"
                     /locus_tag="ACL8CG_000465"
     CDS             6714..8204
                     /gene="lysS"
                     /locus_tag="ACL8CG_000465"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGS1343122.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQSTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            8829..9965
                     /gene="lctO"
                     /locus_tag="ACL8CG_000466"
     CDS             8829..9965
                     /gene="lctO"
                     /locus_tag="ACL8CG_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGS1343123.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPNTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      10217..10305
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10520..11188
                     /locus_tag="ACL8CG_000467"
     CDS             10520..11188
                     /locus_tag="ACL8CG_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGS1343124.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            11431..12213
                     /gene="thiM"
                     /locus_tag="ACL8CG_000468"
     CDS             11431..12213
                     /gene="thiM"
                     /locus_tag="ACL8CG_000468"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS1343125.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVIASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            12215..12844
                     /gene="thiE"
                     /locus_tag="ACL8CG_000469"
     CDS             12215..12844
                     /gene="thiE"
                     /locus_tag="ACL8CG_000469"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS1343126.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      13053..13141
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            13402..13962
                     /locus_tag="ACL8CG_000470"
     CDS             13402..13962
                     /locus_tag="ACL8CG_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1343127.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            13963..15348
                     /locus_tag="ACL8CG_000471"
     CDS             13963..15348
                     /locus_tag="ACL8CG_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1343128.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            15350..16000
                     /locus_tag="ACL8CG_000472"
     CDS             15350..16000
                     /locus_tag="ACL8CG_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGS1343129.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            16011..16703
                     /gene="tenA"
                     /locus_tag="ACL8CG_000473"
     CDS             16011..16703
                     /gene="tenA"
                     /locus_tag="ACL8CG_000473"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGS1343130.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            16708..17232
                     /gene="thiW"
                     /locus_tag="ACL8CG_000474"
     CDS             16708..17232
                     /gene="thiW"
                     /locus_tag="ACL8CG_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGS1343131.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            17232..18035
                     /locus_tag="ACL8CG_000475"
     CDS             17232..18035
                     /locus_tag="ACL8CG_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS1343132.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            18028..18660
                     /gene="thiE"
                     /locus_tag="ACL8CG_000476"
     CDS             18028..18660
                     /gene="thiE"
                     /locus_tag="ACL8CG_000476"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS1343133.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(18869..19660)
                     /gene="thiD"
                     /locus_tag="ACL8CG_000477"
     CDS             complement(18869..19660)
                     /gene="thiD"
                     /locus_tag="ACL8CG_000477"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS1343134.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(19744..19842)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            20026..20421
                     /locus_tag="ACL8CG_000478"
     CDS             20026..20421
                     /locus_tag="ACL8CG_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGS1343135.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            20432..20803
                     /locus_tag="ACL8CG_000479"
     CDS             20432..20803
                     /locus_tag="ACL8CG_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGS1343136.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            20813..23056
                     /locus_tag="ACL8CG_000480"
     CDS             20813..23056
                     /locus_tag="ACL8CG_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS1343137.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRVNGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            23263..25038
                     /gene="spxB"
                     /locus_tag="ACL8CG_000481"
     CDS             23263..25038
                     /gene="spxB"
                     /locus_tag="ACL8CG_000481"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGS1343138.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            25149..25496
                     /locus_tag="ACL8CG_000482"
     CDS             25149..25496
                     /locus_tag="ACL8CG_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1343139.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(25613..26491)
                     /locus_tag="ACL8CG_000483"
                     /pseudo
     CDS             complement(25613..26491)
                     /locus_tag="ACL8CG_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612110.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(26627..26851)
                     /locus_tag="ACL8CG_000484"
                     /pseudo
     CDS             complement(26627..26851)
                     /locus_tag="ACL8CG_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            26892..27212
                     /locus_tag="ACL8CG_000485"
                     /pseudo
     CDS             26892..27212
                     /locus_tag="ACL8CG_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            27333..28277
                     /gene="manA"
                     /locus_tag="ACL8CG_000486"
     CDS             27333..28277
                     /gene="manA"
                     /locus_tag="ACL8CG_000486"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGS1343140.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(28317..29652)
                     /locus_tag="ACL8CG_000487"
                     /pseudo
     CDS             complement(28317..29652)
                     /locus_tag="ACL8CG_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            29880..30629
                     /locus_tag="ACL8CG_000488"
     CDS             29880..30629
                     /locus_tag="ACL8CG_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGS1343141.1"
                     /translation="MYHIKEAAQLSGISVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(30649..31104)
                     /locus_tag="ACL8CG_000489"
     CDS             complement(30649..31104)
                     /locus_tag="ACL8CG_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS1343142.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(31124..32299)
                     /locus_tag="ACL8CG_000490"
     CDS             complement(31124..32299)
                     /locus_tag="ACL8CG_000490"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1343143.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(32358..33203)
                     /locus_tag="ACL8CG_000491"
     CDS             complement(32358..33203)
                     /locus_tag="ACL8CG_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1343144.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            33328..33885
                     /locus_tag="ACL8CG_000492"
     CDS             33328..33885
                     /locus_tag="ACL8CG_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS1343145.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            33904..34371
                     /locus_tag="ACL8CG_000493"
     CDS             33904..34371
                     /locus_tag="ACL8CG_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGS1343146.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            34460..35089
                     /gene="upp"
                     /locus_tag="ACL8CG_000494"
     CDS             34460..35089
                     /gene="upp"
                     /locus_tag="ACL8CG_000494"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGS1343147.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            35263..35853
                     /gene="clpP"
                     /locus_tag="ACL8CG_000495"
     CDS             35263..35853
                     /gene="clpP"
                     /locus_tag="ACL8CG_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGS1343148.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            35932..36180
                     /locus_tag="ACL8CG_000496"
     CDS             35932..36180
                     /locus_tag="ACL8CG_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGS1343149.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            36281..37441
                     /locus_tag="ACL8CG_000497"
     CDS             36281..37441
                     /locus_tag="ACL8CG_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1343150.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            37709..38578
                     /locus_tag="ACL8CG_000498"
     CDS             37709..38578
                     /locus_tag="ACL8CG_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS1343151.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            38582..39538
                     /locus_tag="ACL8CG_000499"
     CDS             38582..39538
                     /locus_tag="ACL8CG_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS1343152.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            39538..40302
                     /locus_tag="ACL8CG_000500"
     CDS             39538..40302
                     /locus_tag="ACL8CG_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343153.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            40302..41012
                     /locus_tag="ACL8CG_000501"
     CDS             40302..41012
                     /locus_tag="ACL8CG_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343154.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGS"
     gene            41426..42082
                     /locus_tag="ACL8CG_000502"
     CDS             41426..42082
                     /locus_tag="ACL8CG_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGS1343155.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIVRTSAKVL
                     "
     gene            42190..43285
                     /gene="prfB"
                     /locus_tag="ACL8CG_000503"
     CDS             join(42190..42261,42263..43285)
                     /gene="prfB"
                     /locus_tag="ACL8CG_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGS1343156.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKMSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTYIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            43303..43995
                     /gene="ftsE"
                     /locus_tag="ACL8CG_000504"
     CDS             43303..43995
                     /gene="ftsE"
                     /locus_tag="ACL8CG_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGS1343157.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            43988..44914
                     /gene="ftsX"
                     /locus_tag="ACL8CG_000505"
     CDS             43988..44914
                     /gene="ftsX"
                     /locus_tag="ACL8CG_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGS1343158.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            45200..47380
                     /locus_tag="ACL8CG_000506"
     CDS             45200..47380
                     /locus_tag="ACL8CG_000506"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGS1343159.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGLIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            47432..48247
                     /locus_tag="ACL8CG_000507"
     CDS             47432..48247
                     /locus_tag="ACL8CG_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS1343160.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            48387..49730
                     /locus_tag="ACL8CG_000508"
     CDS             48387..49730
                     /locus_tag="ACL8CG_000508"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1343161.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYWLTQLMQPYLAMIFVNTKTRADELHSYLTSQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            49945..51135
                     /gene="metK"
                     /locus_tag="ACL8CG_000509"
     CDS             49945..51135
                     /gene="metK"
                     /locus_tag="ACL8CG_000509"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGS1343162.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            51688..52623
                     /locus_tag="ACL8CG_000510"
     CDS             51688..52623
                     /locus_tag="ACL8CG_000510"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGS1343163.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            52657..53694
                     /gene="holA"
                     /locus_tag="ACL8CG_000511"
     CDS             52657..53694
                     /gene="holA"
                     /locus_tag="ACL8CG_000511"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS1343164.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            53867..54472
                     /gene="sodA"
                     /locus_tag="ACL8CG_000512"
     CDS             53867..54472
                     /gene="sodA"
                     /locus_tag="ACL8CG_000512"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGS1343165.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            54629..55159
                     /locus_tag="ACL8CG_000513"
     CDS             54629..55159
                     /locus_tag="ACL8CG_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGS1343166.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            55180..56265
                     /gene="rlmN"
                     /locus_tag="ACL8CG_000514"
     CDS             55180..56265
                     /gene="rlmN"
                     /locus_tag="ACL8CG_000514"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGS1343167.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGTAIGARHIMISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            56265..56747
                     /locus_tag="ACL8CG_000515"
     CDS             56265..56747
                     /locus_tag="ACL8CG_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS1343168.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVRVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            56749..58290
                     /locus_tag="ACL8CG_000516"
     CDS             56749..58290
                     /locus_tag="ACL8CG_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1343169.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(58346..59149)
                     /locus_tag="ACL8CG_000517"
     CDS             complement(58346..59149)
                     /locus_tag="ACL8CG_000517"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGS1343170.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(59232..59444)
                     /locus_tag="ACL8CG_000518"
     CDS             complement(59232..59444)
                     /locus_tag="ACL8CG_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343171.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(59923..60132)
                     /locus_tag="ACL8CG_000519"
     CDS             complement(59923..60132)
                     /locus_tag="ACL8CG_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343172.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            60302..60574
                     /gene="rpsP"
                     /locus_tag="ACL8CG_000520"
     CDS             60302..60574
                     /gene="rpsP"
                     /locus_tag="ACL8CG_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGS1343173.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            60594..60833
                     /gene="kphA"
                     /locus_tag="ACL8CG_000521"
     CDS             60594..60833
                     /gene="kphA"
                     /locus_tag="ACL8CG_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGS1343174.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            61021..61306
                     /locus_tag="ACL8CG_000522"
                     /pseudo
     CDS             61021..61306
                     /locus_tag="ACL8CG_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            61410..62198
                     /locus_tag="ACL8CG_000523"
     CDS             61410..62198
                     /locus_tag="ACL8CG_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1343175.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKKLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            62229..62747
                     /gene="rimM"
                     /locus_tag="ACL8CG_000524"
     CDS             62229..62747
                     /gene="rimM"
                     /locus_tag="ACL8CG_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGS1343176.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            62737..63456
                     /gene="trmD"
                     /locus_tag="ACL8CG_000525"
     CDS             62737..63456
                     /gene="trmD"
                     /locus_tag="ACL8CG_000525"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGS1343177.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            63468..63806
                     /locus_tag="ACL8CG_000526"
     CDS             63468..63806
                     /locus_tag="ACL8CG_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGS1343178.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(63837..64157)
                     /locus_tag="ACL8CG_000527"
     CDS             complement(63837..64157)
                     /locus_tag="ACL8CG_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343179.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            64255..64470
                     /locus_tag="ACL8CG_000528"
     CDS             64255..64470
                     /locus_tag="ACL8CG_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGS1343180.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(64467..64613)
                     /locus_tag="ACL8CG_000529"
     CDS             complement(64467..64613)
                     /locus_tag="ACL8CG_000529"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343181.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKAKLMRFEEI
                     FEEY"
     gene            complement(64674..65210)
                     /locus_tag="ACL8CG_000530"
     CDS             complement(64674..65210)
                     /locus_tag="ACL8CG_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGS1343182.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
BASE COUNT        19778 a        11935 c        14123 g        19548 t
ORIGIN      
        1 tgacagcact ggtggcggta aaaggttaag tacctctatt cgtagcgcct atagtgggtc
       61 agatattacc ccggtatatt cattggggtc tggctctagg attgtcatgt actataatgg
      121 aggtggtgac aattatattg gttctggtac tagattagct atggcgccac aatttggaaa
      181 tcatgtaaga attcatactt caggttcttg gagtccagat tcttattaac ttacttgtca
      241 gagtaagcct taaagatggt tgattgtggg tgtagcatga aaaaagaatg ctacacccta
      301 tttttattat aaggaggagt aaggatggaa tttttcattt gtaatcttgt acgagtcgtt
      361 caatcacctc gattttatat gtctttattt ttgacccttc tttgcatgag tttaggaaat
      421 ttccttgctt tcaatggtat ttataaaatt gaaggtttat cgattttttt tgccgcttct
      481 tctattcgag gattttcacc gattagccta gtagctgcac ttatctgtac actgccctat
      541 tctagtcaga taatagagga tgctgagagt cattttctaa cagcacaatt gtgccgaatt
      601 tctaaaaaga ggtatctagc tattgtaggt agtactgcaa ttatttcttc ttttctagtc
      661 ttttttctcc cctatttatt attattagga attaatcttt tagtgactcc ttatcaggaa
      721 atttatattg gagattatag tggtgcctta aaagaattat ttgattctaa tcagttgctc
      781 tatagtcttg tggcgactct ttggtatgga gtttggggcg ctgtgttctc tatttttgga
      841 ctagctagtg ctttgctagt gaagaaaaaa ataggagcta ttttcatccc agttacctat
      901 atgatggttg gtggtatttt ttgggctatt ttagggctat cttacttaga acctgtgaca
      961 acattagctt tgggatatca gaaagatatc agtctttcct tagttagtgg gcatcttgct
     1021 tttattttat ttgttagttg tttggttgtt tatggtacat tttttctaca ttcagaggac
     1081 tatgtataat gaaacaattt gttcaatttt ataaaaaaga tttcttagca gtattggttt
     1141 attttatatt actgctatcc tgtgttttat ctagtacagt atatttattg cgctgtcgcc
     1201 aatattcaat ccatccaaat gtattagaat ggattttagt tttacttcaa gatatgacga
     1261 ctggagtata ttgctttccg ttcacatata tattgttctt tttttatttg atgaataact
     1321 attttaatag gttggagtgt cgcattcgtc tgaaatcaat taagcacttt accagtttta
     1381 gtttcaaatt agcagctctt agtacgggga tttggacggc gactttattt ttattgattt
     1441 ttctaattgc atttagtaat ggttttagct tctctttgga gataaaggag gttgattttt
     1501 taggagaatt ttatggtata agtattgcaa acaatgctag tttctttata ggattttttt
     1561 tctcttatat agcatactat ttctttttat ccttacttac tattagcagt ttttcttggt
     1621 ttaaaaaatc aaacatgagc ttagtatttc tgtttacttt tttatttgta gaatccttat
     1681 tctggattta tcagttgaac aatgggataa ttggattatt gccaattttt cagtatatgg
     1741 taaattccaa tccgtatgca ttgatttatt ggcttacatt actatctatc ataattccat
     1801 tgactgtatt ttctgttcat agaaactgga ggagagtgta aaagttggaa atgggaaagt
     1861 taagtagtca catgtggagg ttgaatcaga taatctatac caagtacttt tggggttatg
     1921 ttcttttttg gatattgatt tgtttaggat tatggtattg gttagaagga aatgatagac
     1981 ttgttataga aattttaaaa gggcctaatc tgagtcaaaa ctctttttta gtcttatcta
     2041 tatggttgct tcattggttt attattcata cattttttct agcagttgta tatcgtagaa
     2101 gagcatccga tttctttatg gaagtgattc gattttcttc tattaagctc tggattaggt
     2161 atcagatttg gacctgtttt ctttatggac tcattttaat catggtaaaa gttctagtga
     2221 ttcaatttat gttacagtta gcaaactggg atataggagt tttgtttata gttgattctt
     2281 tgaatgcttg tgtgctatcc ttgctttgct ttatgttata cgcactagga gcgaatgtac
     2341 aaatgaactt tgcttgcgtt agtttctttt tactcatgat tgtgtttggt ggtctatttg
     2401 taggaaatcg aactaattat ctattttata ttttgaatcg agggaatgga gatataggac
     2461 gagatttatt tcttcagttg ctatttttag tctttctttt taaaagcatt ttctatttca
     2521 ctcgtcaaaa gaggaggttt atagaatgaa tgaaataatt acattaaaaa atattgagtt
     2581 gaaattaaaa aaaacatgtg tttttcaaaa ccttaatttt agttgtaaac agggggaaat
     2641 tataggaatt actggtgcga atggctcagg taaaagtgta ttgtttaaat taatagctgg
     2701 tttatatagt ccgtcttatg gagaagtgtt aatcaatggg gaaaatattg ttcctgagag
     2761 aaaaattcca gctaatttgg gagctttgat tgaagaacct ggttttataa attattatag
     2821 tggctttaag aatttacaat atttggcaag catacgagga gtagttggta atcaggaaat
     2881 caatgataca ctgaaaatag ttggtctata tgagcaaaaa gaccagaaag ttaaaactta
     2941 ttcgctaggt atgaggaaaa agctagggat tgctcaagca attatggaga atccctctat
     3001 tcttttacta gatgaaccta tgaatgcctt ggataaatca agtgtagaaa atatgagaac
     3061 attgtttaga gagctctcta gtgaaaaagg gacaacaatt ttgattgcta gtcatagtga
     3121 agaggatatt cgtatcttat gtgataaagt atatgcaata gaagataaag tatgtacact
     3181 gtgttcagat tgaacatctt agatagactc aggatgttat aggtaaaatc ttaaaaaggg
     3241 attggagctt aaaatccagt cccttttaag agttaatggc caccttcaac aaccaggtca
     3301 tctgctttag cagcgtcacc gtaggttggg tgaagtgttt tttcataggc cttgtggaag
     3361 aagttttcct tgcctaattt ttcaatatct ttattgatga agtctagcaa ttcttggttg
     3421 tctttttgaa ctgctgccgc aatggtatcg ggatcaccga gggaagtaat tcctacttca
     3481 aatcctttat tttcaagcgc ccaagctaga acttccgtat tgtcagttga aaaggcatct
     3541 ccacgtccgt caagaagagc ttggtaagag tcactgtatt ggtcgtattt ttggagtttg
     3601 atttctggat gattcttttc aaaataagtc tcagcagtcg ttccttttgt gacaattaag
     3661 gttttacctt caagttgttt gacgtctgta atgagaccag tcttaggtga tacgacaccc
     3721 agagaaactt tcatatatgg aagggcaaaa tcaacttgtt tcttacgttc gtcagttact
     3781 gtaaagttag caagagtaat atctaccttg tttgaaatca agtattccgc acggttggcg
     3841 gcatcgactg aaatgtattt aaccttgaca ccaaggtctt gagctagttg gttccctagt
     3901 tcaatatcgt agcgtagcct tggtaagaac catcattgtc aacgtagcca aacggttttt
     3961 tatctccaaa cacggcgatt cgcagttcac cgcttttttt gatttcatcg atagtgcgag
     4021 ctttggcagt tgtttttcca gaggatgaac cagcgtttcc acctgagcta caagcagtga
     4081 taaagataag ggcaaaggca agtgctaaaa cagttaagag tggtttgaat agtttcataa
     4141 gaatctcctt tatagatatg agccgaattg gctaaagtca aagacgttta aaaattcctg
     4201 ggctcgtttg gtttgcagat tggtaaagaa ggcttgagct gttccttctt cagcgatttt
     4261 cccttggtcg aggaagataa tccggtcagt aatggcttgg gcaaactgca tttcgtgggt
     4321 tactaaaatc atggtacggc cttcttgggc caaatcattg ataagttcca gcacctcacg
     4381 caccatttct ggatccagcg aagcagtcac ctcgtcaaaa aggatgattt ctggatgcat
     4441 taggagggca cggacaattg caacacgttg cttctgtcca ccagataatt gacgggcaaa
     4501 gctatgttgt ttatccagca aaccgacacg ctctagtaat tgcaaagctt cttccgttac
     4561 ttctttcttg tcccttcctt gagctttgat agggcctagg atgaggtttt gtaagacatc
     4621 cagatgggga aagagttcat aactttgaaa gaccatgcca atcttttggc gaactaggtg
     4681 aaaatctttt ttattttcaa cgatagactg accatccaga agaatatctc caccttgaat
     4741 actttctaag ccgttgaggc aacgaaggag ggtacttttc ccacaaccag atggccctag
     4801 gatgacaaca acttcccttt tttgatttct agagaaagtc cttggaggat gggattgtct
     4861 ccgaaggatt tttttagttc cttgatttct aagatagttt cagacattta gtttctccaa
     4921 tgtttttcta agtgagtgga tagtttggaa atagggtagc aaactgcgaa atataagact
     4981 agaatggttc cataaatcca aaatgaagca gttgggatgg tcaggcgatt gctatcgatg
     5041 atttgttgtc caactttggt cacttccaca accccaatca aaacaactaa tgaagtggtt
     5101 ttaatcatcc gagtgacaag attgatagcc tgcggtagca gtcttcttaa gacttgtggg
     5161 atgatgatgt ggtagtaaag ttgaacatta gtcaagccga gtgcctattc actttcaaac
     5221 tgatgtttag ggagagaagt gatagctcca cgtaccaagt ctcccatttc agctgttccc
     5281 cagagggtaa aaatgataat agctgaagtc tcacctgaga tattgatatt aaagtttcga
     5341 gccaagccaa agtaaacgat gaagagtagc accagctggg gcatgatacg gataaattcc
     5401 agatacaatc gtgttaaaaa tcgtatgatt ctagaatggg aggtcatgat gattcccatg
     5461 actgttccga acatcatgga taagaggaca gacaggatgg atatcccaat cgtaacgccc
     5521 aacccctgta agattctcag gagattattt ccttgaaaga gtacttggat tcccgaatcc
     5581 tgcatggcgg gtcctccttt ctatccagct aaagaccagt gagatgggta gcagcatgat
     5641 cagataagca actaccaaca tagctagcgc aatgtctgtc tcatagtaga gaccaatcaa
     5701 atccttggcg acgtacatga ggtcggccaa agccactgct gagaaaacag aggtttcctt
     5761 gataaggaaa atgacattgg cactaaagga ggggagtgcc accgctgttg cttgcggaag
     5821 aaccacatag cgaaagacct gtagaggtgt cagaccaata gcgaggccaa tctcctgctg
     5881 ggtttgactg atggcttcca gcccacttcg gaaagattct gccatatagg agcctcctaa
     5941 aaagacaagc ccaagcgttg cacagacttc tgaagatagg acaatcccga ttcggggaag
     6001 accgaagtag agaaagaaga gttgaatcaa aaggggcgta ttacgtgaca attcaatgta
     6061 ggctgtcgct acttgcgcca aaacagggat tcgataatgt cggatgatac taacgattaa
     6121 accgagcaga aaggatccca aaattcccca aactgcaata tgcaaggtca gaaagaatgc
     6181 cttttgatat agtggtagat attgttcaac aatggaccaa tccaaaaata gaacctccca
     6241 tctagaaata atacagttat tgtagcactt aaaatcttct ttggataata tctatttttt
     6301 attgccgtta taaggatttt tatcatagac ataaaatttc tgaaatttcc aaacaaaata
     6361 ttttaaaagt tttgaaaaaa gagttaagat atttttataa tatacaaagt aaacgcttac
     6421 ttattaagga ggacatttta tgtcatacaa aacaagcaat gcagaaggtc atgtagattt
     6481 catcaatacc tatgatttgg agccaatggc gcaacaagtt attcctaaag cagcatttgg
     6541 ctatatcgct agtggggcgg aagatacttt cacttctttc cagtgatttt agcgtcaggt
     6601 tctttttagt ttttaaagat tatccgtgaa tttcttgctt atttatgata aaatgggggt
     6661 atcgcaaaaa atgactcatc gtattcaatt ttgagtaaaa ctaggaggat cccatgtcta
     6721 cagaacatat ggaagaacta aatgaccagc agatcgttcg ccgtgaaaaa atggctgcgc
     6781 tccgcgaaca aggaatcgat cctttcggaa aacgttttga acgtactgca aattcacaag
     6841 aattaaaaga taaatatgcc aacctcgata aagaacaatt acacgataaa aacgaaacag
     6901 ctactatcgc aggacgcttg gtaaccaaac gtggtaaagg taaagtgggt tttgcccacc
     6961 ttcaagaccg cgaaggccag attcagatct acgttcgtaa ggatgctgtc ggtgaagaaa
     7021 actacgaaat cttcaaaaaa gcagaccttg gtgacttcct tggtgtcgaa ggtgaagtga
     7081 tgcgtacgga tatgggagaa ctctctatca aggcaaccca catcacacac ttgtctaagg
     7141 ctcttcgtcc tcttcctgag aaattccatg gtttgacaga cgttgaaaca atttaccgta
     7201 aacgttacct tgacttgatt tctaatcgtg aaagctttga acgctttgtc actcgttcaa
     7261 aaatcatctc tgaaatccgt cgttaccttg accaaaaagg attccttgaa gtggaaacac
     7321 ctgttcttca taatgaagcc ggtggtgctg ctgcccgtcc atttatcacc caccacaatg
     7381 cccaaaacat tgacatggtg cttcgtatcg cgactgagct tcacttgaaa cgccttattg
     7441 tgggtggtat ggaacgtgtc tatgaaattg gccgtatctt ccgtaacgaa ggaatggacg
     7501 ctactcataa ccctgagttc acttctatcg aagtttacca agcttatgca gacttccaag
     7561 acatcatgga cttgactgaa ggcattatcc aacacgctgc taaatcagtc aaaggtgatg
     7621 gcccagtcaa ctaccaaagt actgaaatca agattaacga accatttaag cgtgttcata
     7681 tggtggatgc tatcagagaa attactggtg tcgatttctg gcaagacatg actttggaag
     7741 aagctaaagc tatcgctgct gagaagaaag ttccagttga gaaacactac actgaggttg
     7801 gtcacatcat caatgccttc tttgaagagt ttgttgaaga aactttaatc caaccaacct
     7861 ttgtctatgg acatccagta gctgtatctc cactcgctaa gaaaaatcct gaagaccaac
     7921 gctttactga ccgtttcgag ctctttatca tgactaagga gtacggtaat gcctttactg
     7981 agttgaacga cccaatcgac caacttagcc gttttgaagc ccaagctaaa gccaaagaac
     8041 ttggtgatga tgaagcgaca ggaatcgact atgactacat tgaagctctt gaatacggta
     8101 tgccaccaac aggtggtttg ggaatcggta tcgaccgtct ctgcatgctc ctcactgata
     8161 caacaactat ccgtgatgta ttgctcttcc caacaatgaa ataaattctt atcctctggc
     8221 tcttaccaga ggattttttg attcaaaaag agactgaatt taaggagaaa atgaagtgta
     8281 gtatattgaa gttgaaatag tacactttga tttctaagac attgttagaa attggtttaa
     8341 attccctaag caatttgtgc atgttttatt tcattttacg atagtacgct gaaacttttc
     8401 aaaaagtact agaaattgac ttggattccc caattgattt gttcagattc actataaata
     8461 aaaaattaat aagtgggata ggaagttagc gtcaactagg atagtatctt gcttaaacag
     8521 tatatatggg actgatataa gtccataggt cctattagag gatgttctgg tgtcttattc
     8581 acttgttttt ttatagtatt agtagataga atcagcaaat aaaaaagtag ttcaaatgcc
     8641 tggcagcaaa aaatctcaac gattcactta atatagacta aggtttagag tttaaggaaa
     8701 gtagggctag tatattgtat gaaaaaataa gatggttttt aagcaaaact cttgaaaatg
     8761 attgaaaaaa gagttattat agttgtatag taaaaagcaa acgcttactt aatcgaggag
     8821 gacagtttat gtcatacaaa acaagcaatg cagaaggtca tgtagacttc atcaatacct
     8881 atgatttgga gccaatggcg caacaagtta ttcctaaagc agcatttggc tatatcgcta
     8941 gtggggcgga agatactttc actttaagag agaatatccg tgcctttaac cacaagctca
     9001 tcgttcctca tacactttgc aatgtagaaa atccaaatac agagattgaa tttgcaggtg
     9061 aaaaactatc ttctccaatc attatggcac ctgttgcggc tcataaattg gcaaatgaac
     9121 agggggaagt ggcgactgcg cgtggtgtgc atgagtttgg ttctctttat acaaccagtt
     9181 cttactctac tgttgacctt ccagagattt ctgaagccct tcaagggaca cctcattggt
     9241 ttcaatttta ctttagtaag gatgacggta tcaaccgcca catcatggac cgtgtgaagg
     9301 ctgaaggtta taaagcgatt gtcttgacgg cagatgctac tgtagggggg aatcgtgaag
     9361 tggataagcg taatggtttt gtcttcccag ttggcatgcc gattgttgaa gaatacctgc
     9421 cagaaggtgc tggtaaatca atggactttg tttacaaatc agctaaacaa cgcttgtctc
     9481 cacgcgatgt agaatttatc gctgaatact ctggtcttcc tgtgtatgtc aagggaccac
     9541 aatgccgtga ggacgttgaa cgttcgcttg ctgcaggagc ttctggtatc tgggtaacca
     9601 accacggtgg tcgtcaaatc gacggtggac cagctgcctt tgactcgctt caagaagtgg
     9661 cagaagcagt tgatagacgt gtgccgattg tctttgactc tggtgttcgt cgtggtcaac
     9721 acgtctttaa agccttggca tcaggagcag acttggttgc tattggacgc cctgtcatct
     9781 atggcttggc tctcggtggt agtgtcggtg tgcgtcaagt ctttgaacac ttgaatgcgg
     9841 aattgaagac agttatgcaa ttgtctggag ctcagaccat tgaagatgtc aaacacttca
     9901 agctccgtca caatccatac aacccaacct tcccagttga ccctcgtgac ttaaaattgt
     9961 attgataaaa cagattgcct ccactgaatg tggaggtttt tcttcgtgta ttggaagaat
    10021 aaattgctat cgaaaactat agtaaaatga aataagaata ggacaaatca atcaggacag
    10081 tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatctac
    10141 tatataaaga tatttttcgg tcaaatatct tgctagggct ttcatttttt gctatactgg
    10201 ttcagtaatt aaataataga gacatttggg gtgctttaag ctgagatgat acccattgaa
    10261 cctgatacag ttaagactgg cgaagggaaa tgtgaaacgt tttttcgtat ggcgaaatga
    10321 acgatctaat cttgtaagtc aactctaatt cttgattgta attggagttt tttgtttata
    10381 taaactggat aggcttgttt agttagctct ctgcaaatgc tctcgatgtg ctttaaaagg
    10441 atcaagtgga attacgattt tgcttgatat ttcttggtgt tttattaatt actaacaagt
    10501 aaagagagga gaagtaaata tggaaacaca agactatgca tttcagccag gtttgactgt
    10561 tggagaatta ttaaaaagca gtcagaagga ttggcaggct gcaatcaatc atcgttttgt
    10621 taaggaactt tttgcgggga caattgagaa taaggtctta aaggactatc tgattcaaga
    10681 ttatcacttc tttgatgcct tcttatccat gctgggtgcc tgcgtagctc acgcagataa
    10741 acttgaatcc aagcttcgtt ttgccaagca actaggcttt cttgaagcag atgaagatgg
    10801 ttatttccaa aaggctttta aagagttaaa agtagcagag aatgactatc tagaagtgac
    10861 tttgcaccct gtaacaaaag cctttcagga tctaatgtat tcggcggtgg cttcatcaga
    10921 ctatgcccat cttttggtca tgctggtcat tgcagaaggt ctctatttag actggggttc
    10981 taaagatttg gctttacctg aagtctatat tcattcggaa tggatcaatc tccacagagg
    11041 tcctttcttt gcagagtggg ttcaatttct ggttgacgaa ctcaatcgtg tcggtaaaaa
    11101 tcgagaagat ttgacagaac ttcagcaacg ctggaatcaa gcagtcgctt tagaattagc
    11161 tttttttgat attggttacg atgtctagag aaggctcatg atatttacaa atttgatgag
    11221 gtaagactct tcgaaaatct cttcaaacca cgtcagttct atccacaacc tcaaaacagt
    11281 gttttgagca acctgcggtt agcctcctag tttgctcttt gattttcatt gagtataaat
    11341 cattcaatgt aaatgaaaaa aattcttaac gaaagataga aataaatcga aatcagtaga
    11401 tcgtataaag tgaaaaggaa ggatttcaat atgacaagtt taaaattatt aaaagaaaaa
    11461 gcaccattgg tcatttgtat aaccaatgat gtagtaaaaa atttcacagc aaatggatta
    11521 gtagcactgg gcgcctcacc agccatgagt gagtttccag cagatttaga ggatttgtta
    11581 aagtatgctg gtggtttatt aataaacata ggaacattga cagatgaaaa ttggaaatta
    11641 taccaagctg ctctgaaaat tgcagagaaa tataatgtcc cagcagtttt agatcctgta
    11701 gcctgtggag caggagaata tagaaaaaaa gtagcagatg atctaatcaa caattataaa
    11761 ctagcagcga ttagaggaaa tgctggcgag attgcctctt tagtaggaat agatgtggca
    11821 tctaaaggag tagatagtgc gggcgtagat aatattgacg aaattgctct agcagcaaat
    11881 gagaagttca atattccaat agtagtaaca ggtgaagtgg atgccattgc tgttaatgga
    11941 gaagtggtaa cgattcataa tggtagtgct atgatgccga aagtcattgg gacaggatgc
    12001 ttattagggg cagtgatagc aagctttatc ggactagaaa aaggtcaaga attgaaatca
    12061 ttagaaacag caatgttggt ttacaatatc gctggagaaa tggcagaaaa acgtccaaat
    12121 ggacatcttc ctgggacatt taaagttgaa tttataaatg ccttatacga gattacagat
    12181 gaagatgtaa aggaattcaa aagagtgaag taagatgttt cataaagaat tactaaaact
    12241 atattttatt tgtggaacga ctacttgcca aggaaaaaat ctatatacag tcgttgagga
    12301 agccttaaaa ggtggtataa ccttatttca atttcgagaa aaaggtgagg gtgctttaga
    12361 aggcttagaa aaacttgaac tagctatcca aattaaagaa ctttgtaaaa aatacaatgt
    12421 gccgtttatc gttaatgatg atatcgattt ggcaatggaa attgacgctg atggcgtaca
    12481 tgtaggtcaa gatgatattg gtgttgatga aattagaaaa ttgatgccag ataaaataat
    12541 tggtctttct ataaaaaacg aggaagaatt tcaacaatca aaagttgaat atgtagatta
    12601 tgttggtgtt ggtcctgtat ttgataccca gtcaaaggat gatgctggtg gtgctatagg
    12661 ttatgaaggt cttgaattga tgagaaaact attgccacaa atgcctttag ttgcaattgg
    12721 tgggatacag acgaaacata ttaaagacat tataaagacc aatgttgacg gcgtttcaat
    12781 catttcggca atatcgtatg caaaaaatat agaaaaaact gttcgggaaa tgagtgaaca
    12841 atagatatct atccttggat tctaagtaag taggattttc cttttttaaa aagctatgtc
    12901 tagattcagc ttgaatagct aattcatcaa acaggtcatt tgttttttgc aaaagaaaga
    12961 tctgctgtct ttgtgagtgc aaggctgtat ttccagttca atttcttgaa ctagtataaa
    13021 atgtgtgtta taataatcac ataattaaat aataaaggca tttggggtgc tttaggctga
    13081 gatgataccc attgaacctg atacagttaa gactggcgaa gggaaatgtg aaatgttttt
    13141 ttcgtatgtc gaaaagaact gtctaatctt gtaagctgaa ctctaattcg tatctgtaat
    13201 tagagttttt tcttttacga aactggatga agatgatata gtagattgaa ataagatgcg
    13261 aacaaatcaa ttagaaaatt caaattaatt tctagaaata ttttagcatt cttgtgtact
    13321 gttctaaatt cagtctgcta tacaaagtat ttaggtcggt cttcttgagt gccccacttt
    13381 tctttaaaaa aggagttttt tatgttgaaa aaatggcagt taaaagatgt tatcttgctt
    13441 gctttcttgt ctatcttttt tggtggggtt ttcgttggtt caggatatgt gtataatatt
    13501 ctcagtctac tcttaacacc tcttggtttg caggcctttg ccaatgaaat cctcttcggt
    13561 ctctggtgta tggctgcgcc cattgctgcc atctttgttc cgagagtcgg aagtgcaacg
    13621 attggagaag tgctagctgc gcttgctgaa gtcctttatg gtagccaatt tggtctagga
    13681 gctcttttgt ctggcttggt tcaaggtttg ggaagtgaat ttggttttat cgtaactaag
    13741 aatcgctatg aaagttggct ctctctaact gctaatagta ttgggattac gcttgttagc
    13801 tttgtctatg aatacattaa gttaggttac tacgcctttt cccttccgtt tgtcctttcc
    13861 ttacttgtgg tacgttttat ttctgtttat ttcttctgta ccatcttggt tcgcgccatt
    13921 gtcaaactct atcatcagtt tgcaactgga ggaaaagcat agatgggtct ggaactacga
    13981 gcgattcagt ccccaatctt ctctgagccg tttgatttta cttttcatgc gcaagccttt
    14041 accttgttag ttgggagcag tggttcagga aaatccagcc tttttcaagt cattgctcaa
    14101 gtcagttctc ttccctatag tggtcaagtc ctgatagatg ggagcgaggt cagtcaactt
    14161 tctatcatcg cacgtgtcca gaaggttggc attctctttc aaaatcccaa tcatcaattt
    14221 accatggaga gcttgtttga ggagctgatt ttcaccttgg agaatatcgg ctatcacctt
    14281 caggaaattg attctaaaat agcagaggtt gtccagcaat gtcgttgcga ggcaatctta
    14341 caccgtccca ttcatcacct atcaggtggg gaaaagcaaa aagcagcgct ggctgtcctc
    14401 tttgccatga atcctagggt ctatctcttg gatgaacctt ttgcttccat tgaccgcaag
    14461 agcagaatcg agatattgga gattctaaaa gagttggctc ttgatgggaa gacagttatt
    14521 ttgtgcgacc atgatttatc tgactataaa gcctatatcg accatatggt tgagctaaga
    14581 gacggaaaac taagggaaat aaatcaaatc ccttcctatg agatgacaca ggttgcttca
    14641 aaggaagttg cttctagccc ggaactattc catatgaacc gtgtgactgg tgagcttggt
    14701 aatcgccccc tcttttcaat tgctgatttc acattctatc aagggatttc ctgtatcctg
    14761 ggtgacaatg gtgtcgggaa atcaaccctc tttcggtcta ttcttcaatt tcaaaagtat
    14821 aaggggcgca ttgcatggaa ggggacagtc ctgaaaaaga aaaagagttt gtaccgtgat
    14881 ctgacgggtg ttgttcagga agctgagaag cagtttatcc gagtcagtct gcgagaggag
    14941 cttcaattag atggacctga ttctgaaaga aatcagcgga tttttcaagc tttacgatat
    15001 tttgatttgg agcaggcagt cgataagagt ccctatcaat taagtggtgg tcagcaaaaa
    15061 attcttcagc tcctgaccat cttgaccagt aaggcttccg tgatcttgct agatgaacct
    15121 tttgcaggtt tggatgatag agcctgccat tatttttgca agtggattgt ggaggagagg
    15181 aatcaaggaa gaagttttct gctcattagt catcgtttag accctttgat ttctgtggtt
    15241 gattattgga ttgagatgac tagtcagggt cttcggcatg tgaaagaagt gaccattacc
    15301 aaaccactta catctcagag tagcaatacc caaggggagg tgagatagta tggtcaaagt
    15361 agcaacccag acaccgatta tcagtctctt cttgctgatt ttatccttgg aaacatcttt
    15421 cattccttcg attgctctga atctttcggt agtcgcattt tgtattctct ttatgctcta
    15481 ttaccgtcga tttaaaatgt tagcttggat gatcatactt gccattttac catcttttgc
    15541 caactactgg gcagttcagt tacacggaga tgcttcacag gcagtcatgc ttggaacgag
    15601 ggcctttgtg acagtttgta tcggccttgt ctttgtttcc tctatttcac taaaagagct
    15661 tctcttgtac ttggctcaaa aggggctatc acgctcttgg tcctatgcct tgattgtggt
    15721 attcaattcc tttcctctca ttcagcaaga aatcaagtcc ctcaaagaag cttgcctatt
    15781 acgtggtcaa gaactgcatt tttggtcgcc cttgatttac agtaaggttc tgatgacagt
    15841 ctttaggtgg cgccatcttt acctgagagc tctgtctgct catggatatg acgaacatgc
    15901 acagttgaag aatagctatc ggacttttta tattcctaaa aaaacaaaat taatctacct
    15961 gcttttcttt ttattgcttc aaaccagtct atttttataa aggagttatt atggaattta
    16021 cagatattgc gatggaatta tccaagaaag cttggcaggc ttcctttcat catcccttta
    16081 ttttacaatt acaagagggg aatttagaac ctgccatttt ccgctattac ctgattcagg
    16141 atgcctacta tctgaaggct ttctcagaaa tctatcatct tttggctgat aagacttcaa
    16201 accaagagat gaaaagactc ttgaaacaaa atgctcaggg tttagtggag ggtgagttat
    16261 ttattcgcca acaatttttc aaggaattgg aaatcaacga ccaggaaatg gagcaacatc
    16321 caatcgctcc aacctgttat cattacattt ctcatattta taggcaattt gcagaaccga
    16381 acttagccat agcttttgca agcttgcttc cttgtccttg gttataccat gatataggca
    16441 aatcacttaa tcttaaacca tcaccaaatc ctctctatca acaatggatt gaaacttata
    16501 ttacggatga gttagagcaa cagatcagag aggagggagc actggtcaat cagctctatc
    16561 gagaaagtga tgagacagat aagcaaaaaa tgctagatgc cttccacatc agtgttcata
    16621 tggaagccaa gttttgggaa atggcctacc aacaccagac atggaagagc gatttacagt
    16681 ctttagaaaa aggagaagaa tagaagcatg agaaagcacc aattacaagt tcacaaatta
    16741 accattttat ctatgatgat tgcccttgat gtagtcctga cacctatctt tcggattgag
    16801 ggaatggcac cgatgtccag tgtagtcaat attctagcgg gaatcatgat gggacctgtt
    16861 tatgccttgg ccatggctac agtgacagcc tttatccgta tgacgactca agggattccg
    16921 cctttagctc tcacaggagc gacttttgga gcccttctag caggtctctt ttataagtac
    16981 ggtcgaaaat tttacttttc tgccttggga gaaattgtgg gaacaggtat tattggctct
    17041 attgtttcct atcctgttat ggtactcttt acaggatcag ctgctaagct tagctggttt
    17101 atctacacgc ctcgattttt cggagcaacc ttgattggta cagcgatttc ctttattgcc
    17161 tttcgatttt taatcaagca ggaattcttt aaaaaagtgc agggatattt ctttagtgaa
    17221 aggatagact gatgcaggaa tttacaaatc cctttcctat aggctctagt tccctaattc
    17281 actgtatgac caatgagatt tcttgtgaga tgctggcaaa tgggattttg gctctgggat
    17341 gcaaacctgt catggcagat gatccccgtg aagttcttga ttttactaag caaagtcagg
    17401 ctctcttcat caatttgggg catttgtcag ctgagaagga aaaagcaatc cgcatggcag
    17461 cttcgtatgc aaaccaatct tctctcccga tggtagtaga tgcggttggc gtaacgactt
    17521 catccattcg taagagctta gttaaagacc ttttagacta tagacctacg gtccttaaag
    17581 gaaacatgtc agaaattcga agtcttgttg gcttaaagca ccacggcgtt ggggtcgatg
    17641 cgagtgctaa agatcaagaa acggaggatt tgcttcaagt cttgaaagac tggtgtcaga
    17701 cctatcctgg tatgtctttc ttagttactg gccccaagga ccttattgtt tcggagaatc
    17761 aagttgctgt actggagaat ggctgtactg aattagactg gataacaggg acaggagact
    17821 tggttggagc cttaacagcc gtttttctca gccaaggaaa gactggtttt gaagcttctt
    17881 gcttagcagt ctcttatctc aatatcgctg ctgagaaaat agttgttcaa ggaatgggat
    17941 tggaagaatt tcgttaccaa gtactcaatc agctttcgct cctaagaaga gatgaaaatt
    18001 ggctagatac catcaaagga gaggtttatg aatagagaag cacttagact atatctggta
    18061 accaatcgct atcaagattc cgtggaaagc tttcttgcaa aagttgagac ggcctgccgt
    18121 tcaggggtta ccatagtcca attgcgagaa aaaaatctca caaccaatca atattatcaa
    18181 ctggcaaaac aagtcaagga aataacagat gcctatcagg tccccttgat aatcgatgat
    18241 cggttggatg tttgtcttgc ggttgatgct gctggtctgc atattggaga tgacgaactc
    18301 ccagtttcgg ttgcccgaca agtcttgggt cctgaaaaaa tcctcggtgt caccgctaaa
    18361 acggttaaaa gagctctgga agcggagaaa tcaggtgcag attacttggg gacaggagcc
    18421 atttttccga caaccaccaa ggaaaatgca cccatcaccc tgatttcaac cttgaaaaca
    18481 atttgccaaa cggttgccat tccaatagtt gctattggtg gcttgacttc ggagaatatt
    18541 gatcagctta tgggcactgg catagctggt gtagctgttg tacgtgattt gatgcaagca
    18601 gaagatattg aggcaaaaac gcaagccttt ttaacaaagt tgcatgacat tctttcctaa
    18661 ttaatactca atgaaaatca aagagtaaac tagaaagcta gtcgcaggtt gctcaaagta
    18721 ctgccttgag gttttagata agactgacga agtcagctca aaacagtgtt ttgaagttgc
    18781 agatggaagc tgacgtagtt tgaagagatt ttcgaagagt ataaaaactc tctaattccc
    18841 ttaaagtggg aactagagag tttttttctt aatctttaaa agttgtatgg ttgactggac
    18901 cagaaccatg accgagttga ggggcatctt gaatagcttt tgtgataaag gccttggcct
    18961 tatcaactgc ctggtaaaga ctcttgccct tggctagttc agcagtaatc actgcagcaa
    19021 aggtacatcc agtaccatgg gtgtgacagg tttgaattcg tgggctttcc cagacaaatt
    19081 gttcattctt ggtaaagagg aaatctttag caccaccttt gagatgtccg cctttgataa
    19141 ccacagactg aggaccaaat tcttttaaaa tcaggcgacc agcacgctgc atgtcttcgg
    19201 ggtcatggat tgaaaaacca acaatctctt ctgcttcagg aagatttggc gtaataatag
    19261 ttgctagagg tagtaagttt gttttgagat agtctctagc acttgagtca atcaaggcat
    19321 ctccacttgt agcaaccata acaggatcaa ggacataggg acaatccagt tttttaagat
    19381 agggttggat gatttccatg atttcagtag tagccaacat tccagttttt acagcctgag
    19441 gtggaatatc agaaaagaca ctctccaatt gggctttcaa catttgagga gaaacgtgct
    19501 cgattagctg aacacctctg gtattttgag cgacaagact ggttacaaca gccattccat
    19561 agacatctct cgcttggaat gactttaaat ctgccataat gccagcacca ccactagggt
    19621 cagtccctgc aatggtcaaa gcaacgggta aataagtcat ctaaaacctc ccaaccaact
    19681 gaagtttgta ttcttaagaa caagctagtc tgttttagaa aggcaataga agactgctag
    19741 tccccattat catttccact tccatcagct agcattacct agattgagtc agagggatct
    19801 aacagtcgtt aatctcagct ttacgcaccc ctagtggttg ttttcttttt tctttagtat
    19861 agcatatttt tattgtttat atagtaatat ttgactgcaa atcgtttttc aaatgattaa
    19921 aattctattt ttcgaagaaa atattatttc tataattgac aaatgtagat tttaagagta
    19981 tactgatgag tgtaattgac aaatgtagat tttggaggta tggtaatgca gatttcagat
    20041 gcagaatggc aggtcatgaa gattatttgg atgcaggggg agcagaccag tacggatttg
    20101 attagggttt tggcagagcg atttgattgg tccaagtcca cggttcagac acttttggct
    20161 cggctggttg agaaagagtg tttgactcgg aaaaaagaag gcaagtcctt tgtttattca
    20221 gcccttttaa ctctagacca aagtcgggat ttacttgtcc aagatatcaa agacaaggtt
    20281 tgttcccgta ggattaggaa tttgttggct gacttgattg tagaatgtga atttactcag
    20341 actgacttgg aagacttgga agctgtgatt tcagagaaga aatcaagtgc tgtaacagaa
    20401 gtaagatgta attgtatgta aaggagacgt catgttaaat agtattgtaa ccattatttg
    20461 tattgccctt atcgcgttta tcttgttttg gtttttcaaa aagcctgaaa aatctggaca
    20521 aaaagcccag caaaaaaacg gataccaaga gattcgagtg gaagtcatgg gaggctatac
    20581 tcctgagttg attgtcctca agaaatcagt gccagcacgc attgtctttg accgcaagga
    20641 tccttcacca tgtctggatc aaattgtttt tccagatttt ggtgtacata cgaacctgcc
    20701 aatgggggaa gagtatgtag tggaaatcac gcctgagcag gctggagagt ttggctttgc
    20761 ttgtggtatg aacatgatgc acggcaagat gattgtagag taggtggaga ctatgacaga
    20821 aattgtgaaa gcaagcttag aaaatggcat tcaaaaaatc cgtatccgag ctgaaaaagg
    20881 ctatcatcca gcccatatcc agcttcaaaa gggaattcca gctgagatta cctttcatcg
    20941 tgctactcct tcaaactgtt ataaggaaat tctgtttgaa gaagaaggta tcttggaacc
    21001 aatcggcgta gatgaggaga aagtcattcg ttttacacct caagaattag ggcgacatga
    21061 attttcttgt ggcatgaaga tgcaaaaggg aagctatata gtcgttgaga agactcgaaa
    21121 atctctatct ctcctgcaac gtttttggat tactagtatc tttactgtgc ctcttgtgat
    21181 tctcatgatt gggatgttgg caggtagcat tagtcatcaa gtcatgcatt ggggaacctt
    21241 tttagcaaca acgcctatta tgttagttgc aggtaagcca tatatccaga gtgcttgggc
    21301 cagttttaaa aagcacaatg ccaacatgga taccttggtt gcgctgggaa ctctagtggc
    21361 ttatttctat agcctagttg ctctctttgc tggtctccct gtttacttcg aaagtgctgg
    21421 atttatcctc tttttcgttc ttttgggagc agtttttgag gaaaaaatga gaaaaaatac
    21481 gtcccaagct gtggagaaat tactggactt gcaagctaaa accgcagaag tcttgagtga
    21541 tgatagttat gtccaagttc ctttggaaca agtcaaggta ggcgacctga ttcgagtgcg
    21601 tcccggtgaa aagattgctg ttgatggtgt cgtagtagaa ggtgtctcta gtattgacga
    21661 atccatggtg acaggtgaga gtctgcctgt ggacaagaca gttggagata ctgtcattgg
    21721 ctcaaccatc aatcatagtg gaacgcttgt ctttagagca gaaaaagttg gctcagagac
    21781 tgttttggct cagattgtgg attttgtgaa gaaagctcag acaagtcgtg cgccgattca
    21841 ggacttgacg gataagattt cagggatttt tgtcccagta gttgtcattt taggaatcat
    21901 gaccttttgg gtttggttcg tcttgctcag ggatagtgtg gtcgtgcttg gagctagctt
    21961 tgtgtcctct cttctctacg gagtggcggt tttgattatc gcctgtcctt gtgccttggg
    22021 acttgcaaca ccgacagccc ttatggtggg gacaggacgt agtgccaaga tgggggttct
    22081 cctcaaaaat ggaactgtct tacaggaaat ccagaaagtt caaactcttg tctttgataa
    22141 gaccgggact ttgacggaag ggaaacctgt ggtaacagat atcatcggcg acgaagtaga
    22201 agtgtttgga ttggcagcct ccttggaaga tgcttctcaa cacccactgg ctgaggctat
    22261 cgttaagcga gcgagtgaag ctggacttga gtttcaaact gttgaaaatt ttcaggcctt
    22321 gcacgggaaa ggtgtttcag ggcgagtcaa tggaaaacaa gttttacttg gaaatgctaa
    22381 aatgctggat ggcatggata tttctaatac ttatcaagat aaactagaag aactagaaaa
    22441 agaagctaag acagttgtgt ttttagctgt tgacaatgaa atcaaaggct tgcttgcttt
    22501 gcaagatatt cctaaggaaa atgctaagct agccatcagt cagctaaaaa aacgtggtct
    22561 ccgaacagtc atgctgacag gagacaatgc tggtgtggcg cgtgctattg cagatcaaat
    22621 cggaattgaa gaggtcattg caggcgtctt gccagaagaa aaagcccatg aaatccataa
    22681 actgcaagcg gctggcaaag tagcctttgt tggggacggt atcaatgacg ctcctgccct
    22741 tagtgtagca gatgtgggaa ttgctatggg tgctggaaca gatatcgcca tcgagtcagc
    22801 agatttggtg ttgacaacca ataatctttt aggagtggtt cgtgcctttg atatgagtaa
    22861 gaaaaccttt catcgaattc tactcaatct tttctgggct tttatctaca atgttgtcgg
    22921 aattccgatt gcagcaggag tcttttcagg tgttggactg gctctcaacc cagaattggc
    22981 aggtctagcc atggccttta gttctgtatc tgttctgacc agttcccttc tgttaaattt
    23041 tagtaaaata gactaaaagt aatgactaga tttctttgtt ataaaacaga aatgacaaca
    23101 ctttcaaaac tgtattagaa tagagaatag agagttttga gcagattttt agaaaagtca
    23161 gcataaatat gatacagtgg aatagtaaaa atttggagaa cgtttccaat tctatgtaat
    23221 cgtattctcc aagtttaaaa aaattgaagg agagttatca ttatgactca agggaaaatt
    23281 actgcatctg cagcaatgct taacgtattg aaaacatggg gcgtagatac aatctacggt
    23341 atcccatcag gaacactcag ctcattgatg gatgctttgg ctgaagacaa agatatccgt
    23401 ttcttacaag ttcgccacga agagacaggt gctcttgcag cggttatgca agctaaattc
    23461 ggcggctcaa tcggggttgc agttggttca ggtggtccag gtgcgactca cttgattaac
    23521 ggtgtttacg atgcagctat ggataacact ccattcctag cgatccttgg atcacgtcca
    23581 gttaacgaat tgaacatgga tgctttccaa gagcttaatc aaaacccaat gtacaacggt
    23641 atcgctgttt acaacaaacg tgtagcttac gctgagcaat tgccaaaagt aattgacgaa
    23701 gcctgccgtg ctgcagtttc taaaaaaggt ccagctgttg ttgaaattcc agtaaacttc
    23761 ggtttccaag aaatcgatga aaactcatac tacggttcag gttcatacga acgctcattc
    23821 atcgctcctg ctttgaacga agttgaaatc gacaaagctg ttgaaatctt gaacaatgct
    23881 gaacgcccag ttatctatgc tggatttggt ggtgttaaag ctggtgaagt gattactgaa
    23941 ttgtcacgta aaatcaaagc accaatcatc acaactggta aaaactttga agctttcgaa
    24001 tggaactatg aaggtttgac aggttctgct taccgtgttg gttggaaacc agccaacgaa
    24061 gtggtctttg aagcagacac agttcttttc cttggttcaa acttcccatt cgctgaagtt
    24121 tacgaagcat tcaagaacac tgaaaaattt atccaagtcg atatcgaccc ttacaaactt
    24181 ggtaaacgtc atgctcttga cgcttcaatc cttggtgatg ctggtcaagc agctaaagct
    24241 atccttgaca aagtaaaccc agttgaatca actccatggt ggcgtgcaaa cgttaagaac
    24301 aaccaaaact ggcgtgatta catgaacaaa ctcgaaggta aaactgaggg tgaattgcaa
    24361 ttgtatcaag tttacaatgc aatcaacaaa catgctgatc aagacgctat ctactcaatc
    24421 gacgtaggta acactactca aacatctact cgtcaccttc acatgacacc taagaacatg
    24481 tggcgtacat ctccactctt tgcgacaatg ggtattgccc ttcctggtgg tatcgctgct
    24541 aagaaagaca atccagatcg ccaagtatgg aacatcatgg gtgacggagc attcaacatg
    24601 tgctacccag acgttatcac aaacgttcaa tacgaccttc cagttatcaa ccttgtcttc
    24661 tcaaatgctg agtacggctt catcaagaac aaatacgaag atacaaacaa acacttgttt
    24721 ggtgtagact tcacaaacgc tgactacgct aaaattgcgg aagctcaagg agctgttgga
    24781 ttcacagttg accgtatcga agacatcgat gcagttgttg cagaagctgt taaattgaac
    24841 aaagaaggta aaactgttgt catcgatgct cgcatcactc aacaccgtcc acttccagta
    24901 gaagtacttg aattggatcc aaaacttcac tcagaagaag ctatcaaagc cttcaaggaa
    24961 aaatacgagg cagaagaact cgtaccattc cgtctcttct tggaagaaga aggattgcaa
    25021 tcacgcgcaa ttaaataatt cctctcgccg aaaatcaaat atgaaacttg tagactttat
    25081 tctttgattt tcatagagca gaactttaaa agatcggagc aatccggtct ttttatggag
    25141 gagagtaaat gaatttaaat caattagata ttatcgtttc aaatgttccc caagtctgtg
    25201 ctgacttgga gcatatcttg gataaaaagg cagattatgc tgatgatggt tttgctcagt
    25261 ttacgattgg tagtcactgc cttatgttgt cacaaaatca tttggttcct ttggaaaact
    25321 ttcagtcagg aatcattatt catatcgagg ttgaggatgt agaccagaac tacaaacggt
    25381 tgaacgagct tggtataaag gttttacacg gaccaactgt aaccgattgg ggaacagagt
    25441 ccttattagt tcaaggacct gctggtctag tgcttgattt ttatcgtatg aaataggtcg
    25501 cgtagtcatt tgacgttaac cttagctatt tttaaaatag aaattgagaa tatgaactat
    25561 tgaaagatcg gagcaatccg gtctttttat ataaagaaat tgcatataat actcatctgc
    25621 tttcaaaaag cattctagtc catctccgat taacgatgga ctttatcacc tccttctcca
    25681 gtccttgtat gacatcttga agttgattaa tgacatcttc caaagttcga aaggctttat
    25741 tcttaaatcc acgtttacga atctctttcc acacttgttc aatggggttc atctctggtg
    25801 tgtatggagg aataaatgca aagccaatat tagtcggaat ctttaaggta cttgatttat
    25861 gccatatagc attgtccata acgagtaaaa aataatcata tggataagct tgtgaaagct
    25921 cttctaaaaa gacgttcatc cactcagtat tacatccacc agctcttaag aaaaatgatt
    25981 cgcctgtata ggcatcaaca gctccataac aatagcgaaa ttctcgtata tagtgactat
    26041 gaacatgtgg acctactcct atttgagacc aacaagatcc cagtttactg attctaccga
    26101 aaccagcttc atcttggtac atcaagcgaa ccttacgaaa acgtctactg gttttaaagc
    26161 gctttcttgt cttctttaat tgagatttta tttttagaca cgacaatggt ttgagcgtct
    26221 gctttcttag gatgttctgg acgtggcata atatttcgcc aatcatggcg cttcaacagt
    26281 tgatagaagg catcacgtgt gtaggaacga cctaactcct ttttataagc ctgaaataag
    26341 gcatcaattg taacaaattc tcctgcctct gcagccttca aatggcgggc aagaaaggct
    26401 ttttcttcct caactgtcat atatgatggt tacgaccacc acgtgtttct tgaaggagag
    26461 agtcgagtcc gaactcctca tattttttta catttcgcca aatcgttgtt tgattacagt
    26521 ctatagtgta ttgaatctat gacagtacac cttggctgct aaaatatttc tataaattaa
    26581 tttgactttc ctgatagagt tgttcacatc ttatttcaaa ccactataaa agttctataa
    26641 tctctttata agatttgccc atcaggcgaa atataataga ttgaaactag aatagtacac
    26701 ctctacttct aaaacattgt tagaaatcga tttgtcctgt tcttgtttca ttttactata
    26761 gaacgatttg aaggcgttta taatatttag ctgtacgaga gtcttttaaa agtgttttga
    26821 tggtttggat ttcttcttta gttgatttca tattactatt gtataatgct ttttgatttt
    26881 agtttagtat tatcgtagaa aatggactcg gtgctatgga tacaccggat gagaatggtt
    26941 atgtagcaga tgactatcgg attacttact tagaggccca catcaaggcc atgcgagatg
    27001 ccatttacca agacggggtt gacttgcttg gttatacgac ttggagctgt atcgatccgg
    27061 tttcagctgg cacaggggaa atgaataagc gctatggctt tatctatgta gatcgagata
    27121 atgtaggaaa tgggactctc aaacgtagca agaagaagtc cttctattgg tacaaggatg
    27181 tcattgatag caatggtgta agcatcgagt agagcacatt tgtttactat ttttataaaa
    27241 tcttctccct gctttataag atgtaaaaaa gagttcaaat ggaactcttt ttttgctata
    27301 atgaggggag aaaaatcaga caggagatta agatgtcaga accattattt ttacaatcag
    27361 ttatgcaaga aaaaatctgg ggtggtacca agctacgtga tgagtttggc tacgacatcc
    27421 caagtgaaaa agtcggagag tactgggcta tctcagctca tctaaatggt gtttctaaag
    27481 ttgccaatgg tcgttacgag ggaacagatc ttgctacttt gtatgcggaa caccgtgaat
    27541 tatttggcaa tcgtcctgag cctgtatttc cacttttgac caagatcctc gatgccaacg
    27601 actggctcag tgtccaagtt cacccagacg atgcttatgg actcgagcat gaaggcgaac
    27661 ttggaaaaac agaatgttgg tacatcattg cagcagatga aggttcagag attatctacg
    27721 gtcacaatgc caagtcaaaa gaagaactcc gccagcaaat cgaggataag aactgggatg
    27781 cgctgttgac aaaagtgcca gttaaagcag gagatttctt ctatgtacca agcggtacca
    27841 tgcacgctat cggggcgggt atcttgattc ttgaaaccca gcagtctagc gataccactt
    27901 accgtgtcta tgactttgac cgtaaggatg acaagggcaa tttacgtgaa cttcaccttg
    27961 aaaaatctat cgatgtcttg aacattggtg aacccgcaaa tagccgtcca gtgacaatca
    28021 aagcagatga tctacgttcc actctccttg tatccaatga tttcttcgca gtttacaaat
    28081 gggaaattac tggaaaagtt aactttgaaa agacagctga ctacagcttg ttgagtgtct
    28141 tggctggtca aggtcaacta actgttgacg ggaaaaacta tccaatccaa aaagggagac
    28201 actttatcct accaagtgat gttgaatctt ggactctaga agggcaagat ttggaattga
    28261 ttgttagcca tccataaaaa gaaagggcct gagttcacta ctcaagtcct ttttgattac
    28321 ataaattggg caatgaagac cacaatgatg atgattggaa tgacgaaacg aagaaacgaa
    28381 gaaggaagag ccagacttgg aacagtcctt gtttccatgc tctttcatcg agatggagtt
    28441 cctccattgc aagagccttt ttaaagatat agcctgtaaa aagtgaaagg tagagagctc
    28501 caaatggcat gaggagattg gaagccaaga agtccatagc gtcaaagaag atcttaccaa
    28561 aaatgtgaac atccgccatg acaccgtaag atagggctga aggaatgcca aagacaaagg
    28621 tcaaaattcc taaaataaca ctccatttgg cacgtttgct gttatcctgg ttggtgatat
    28681 tgcccacatt gatctccagc atcacgacag aagaagtgac agtcgcaaag aggaaaagga
    28741 cgtagaaaat ggttccaaaa ggcatcttgt caaaaagttg aggcaagacg ataaagagca
    28801 agctcggtcc cccttcagac tggatattga aggctgacat ggctgggaaa atggctagac
    28861 ctgccatgat ggatatcgag atattcatgg ctacgatgga gattcctgac tggactagat
    28921 tggttttctt gtccaagtaa gaagcatagg tcaacatgac tgtaacccct agtgagaggg
    28981 caaagaaaga ttgtcccaga gcatagagga gatcagcgct agtcagtttt gaaaagtctg
    29041 gtttgaggaa gtaaagaacc ccttccatgg catttgacaa gctgagagag tgaccgatga
    29101 taacaacaaa gatgataaag agcaggggca tcatgacttt cgaagctctt tcaatccctt
    29161 tttgaacccc acgtgataca atgaagatat tcaataggat aaaggccgct tgagctccta
    29221 gggcaatggc tggatttgaa atgattgaag taaataactg agcataatca cccgttccac
    29281 caagttggaa caatttccca aactcaatac ctagatagac tagaatccat cctccgataa
    29341 cactgtaaaa agataagagg ataaagaggg caaaggcgcc aatccaaccg ataaagttgt
    29401 acttgttatt cttgcccagt tttccaaagg ttttgatagc ggaaacgcca gcactacggc
    29461 caagggcaaa ctcagccagc aggagaggga aatcgattaa aatagtggaa atgagaaaga
    29521 ttagtaaaaa gcctccaccg ccattagcag cagtcatgta gggaaacttc caaacggcac
    29581 caagcccgat ggccagccag cagatgctag aataaaacca agtttcgacc cccattgtga
    29641 tttttctgac atagttaaac tctgatctcc tttttcaaaa taagaaaaag ctacttgagt
    29701 tgtcaaatag ccttctgttt gattgataga cttgactatc ctatcatgtt ttctaaggtc
    29761 tgtcaagaaa atcattttca agttttcaca cctttctcaa aaaagttaaa aaattttctc
    29821 aaaaacgctt gactctgacc taaggggagg ggttatacta tcattgtaag gaggaaatca
    29881 tgtaccatat aaaagaagct gcgcagcttt caggtatctc tgtcaagacc ctgcatcact
    29941 atgacaagat aggactcttg gtccccttaa agtcggaaaa cggctatcga acctacagtc
    30001 aagaggattt ggaacgcctt caggtcattc tttactacaa atatctaggc ttttctttag
    30061 agaaaatagc agagctgtta aaggaagaaa ggacagattt attgccccat ttgactaggc
    30121 agttggacta tctaactcgc gaaaggcaac atctggatac cttgatttcc accttgcaaa
    30181 aaactattca agaacaaaaa ggagaaagaa aaatgaccat tgaggaaaaa ttcacgggat
    30241 ttagctatca agacaatcaa aaataccacc aagaagcggt agagaaatat ggtcaagaag
    30301 tcatgggaca agcgctcgaa cgccaaaaag gtcacgaaga cgaggctacg gccgccttta
    30361 accaagtctt tcaaactttg gcacaaaatc ttcaagttgg tttacctgca acagcaaccg
    30421 aaaaccaaga gcaagcagcc aagctcttgc aagccattcg cacttatgga tttgactgct
    30481 ctattgaggt attcggtcat atcggtaaag gttacgtcta taacccagag tttaaggaaa
    30541 acattgacaa gtttggttct ggaacagccc agtacacgtc agatgccatt gcagcttacg
    30601 ttcagacaaa tgcagaaaaa ataggctagg aatttcctag cctatttttt acttcaaatc
    30661 ataaagccag tcgtcaccgt ttttgtagta aaagaattca ctgagatctt cttctagaaa
    30721 cacacgaagc atatcagaca tatcatcggt tgcaagtttt agatgagaaa gattttcaaa
    30781 gtcctcccac caaactttcc cttcgtctga agactggagt tcaccagtaa agtgttctgt
    30841 cttgtaaaaa aggacgacat aacgataatc cttgtcgtca taccagtttt tgataccaca
    30901 gagttggggt ttggaaatga tcagaccagt ttcttctttc acttcacgaa tgacagcatc
    30961 gacaaaggat tcgccacgtt caacatgacc accaggaaaa gtaatgccag gccagtcggg
    31021 actaactcgg tcttggacca ggaccttatc tccgttttta atcatacaca tgttaacaaa
    31081 ttcgactgcc tctcttctgt tcattcttca caacctttaa tctttaatca taatgcagac
    31141 ttcccgccac ccagccggta cagagggcag aagtgatgtt aaagccaccc gtgtgggcat
    31201 tgatatccat aacttcgcct gcaaagtgga ggccaggtac cagcttactt tcaagggttt
    31261 taggattgat ttccttgaga ctgactccac ccttggtaac aaaggacttt gcaagggaca
    31321 tttttccagt tacaggaatt ttaagttctt taatggactg gacaagctgt tctcgttcct
    31381 tttcagtcag ctgtttgact ttttcaggat atccttgtac aaaaaattcg gccaagcgtt
    31441 ctggtaacaa ggtttttaaa gcgtttttca aggatttttc ccgattttct tctagaaatg
    31501 taaccaagtc cttctcagaa agttgaggca aaacatcgag tgagagaacc tccccacctt
    31561 tgacaaagct agacatgcgt agggcagcag gacctgacaa accaaagtgg gtaaagagta
    31621 aatcatgagt gatgacatgc ttaccataac ttagggtcac atcgtccaga gaaatccctt
    31681 gtaaggcttt atgtggaaaa tctgttaata aaggactttc agcagcctca agatcggtga
    31741 tggtatgctt aaaatggcga gcaatctcgt gaccaaaacc agtcgaacca gtcgaaggat
    31801 aagacttacc acctgttgtg acaatgagtt tctcacaagt gaaggtttga tccgctgact
    31861 taaggacaaa ctggtcatct acttttttaa cagaaacgat ttctatttga gtagcaactt
    31921 gaccacctag ttcagtgatt ttcttttcca aagcttcgat aatagtccga gacttgtcac
    31981 tggctggaaa gacgcgtccg tggtcttcga ccttaagttt aacaccattt tctgtaaaaa
    32041 agttgatgat gtcatgatta tcgaactggg agaaaacact gtaaagaaag cgtccgtttc
    32101 caggaattcc agctagcagg ttgtctaagc taccattgtt ggtcacattg caacgtcccc
    32161 caccagtccc agctaatttt tttccaagtt tccgattttt ttcgatgagg agggttttct
    32221 gtccataaaa gctactggaa atcgtagcca tcataccagc aggtccccca ccgatgacaa
    32281 tagtatcaaa atgtttcata gctctattgt accacaaaaa aacaagagat gatggtcacc
    32341 tcttgtcaag aatgcaatta atcaatttca tagcccatca gcaaaccgcc ctcttctgca
    32401 tagaaactgc agagaccaga ggttggtaga attttaatat ccgcttgtgg gaaggtttca
    32461 cggattcgct ctgagagctg ttgacaacat ttttcgttat tgcgttgggc catgacaata
    32521 cggccaccag catatccagc ttttactaac tcatcatagg cagcttgaac tgatttcttt
    32581 gatccccttg ctttttgtag caattcgaga gttccagttt cactagcttt tccgaccata
    32641 cgaatgttga gaaggccaac gaccgtaccg ataagcttgc tcaaacggcc gttcttcacc
    32701 aagttatcga ctttggctag gacaaagagc aacttagttt tttcttgata ggcggtgata
    32761 gcttcaacca cttcttcaaa agacaagccc tggtcaatca agtcattcaa tttttctacg
    32821 agtaggtcaa cttcaccacc agcagataaa ctatcaatca catgaatctt agtgtcagga
    32881 tggtcttcca gataaatatt ctttgctagt tgagcactat tgtgactgcc agaaagggta
    32941 cctgtgatgg ttactaggaa aatgtttttg gcaccttcaa atgctcgcaa atagtcatct
    33001 gggcttggac aagccgattt tgaagcttct gcagttgcat acatggtttc catcatttgg
    33061 tcaatatcga gactggcgtc atcaacaaag acctgatcag ctacttgaat ggttaagggg
    33121 acacttacaa aggttgtgtt aatagctggt gttggcagtt gacgataatc acaaccagag
    33181 tcagcaataa ttttccaagt catagaaatt ctccatcttt gtcagttata cattgacaaa
    33241 ggttctgtct ttttttacaa ttatatcatg aaaactcttg aaacaaaagc atcatccgtc
    33301 tgttgtgaca agtagaaaga aaatgttatg tctgaacgta gaatctctga aaagtctctt
    33361 gaaaatctca gaaaatcaaa ccaagaatcc aatttattaa ccagagaagc cattgaaaca
    33421 gccctcttgc aactcttgga aaaaaaggag ctgaccaaga ttagtatttc tgaattggtc
    33481 aaacgtgcag gtgtttcgcg tgcggccttt tatcgcaatt atgactccaa agaggaaatt
    33541 ttagagagcg tctttaaacg aactgtccac aatattatgg aacagctgca tcattacgat
    33601 ttaaagacag acctttattt ggtttgggtt caccttttcc gggaggccag aaaggaagct
    33661 agagtgattc aattggcctt ggattaccat ctggaaaaaa tctttgtcca agccatgcag
    33721 gaatttctag aaaaatacca tgggaaatca aaaggtgtca gctcttatct tcattccttc
    33781 tggagctcag ccattgtctc tgtccttcta aaatggatca aggatggcat gaaggtacca
    33841 gctgaaaaga ttgcagattt aggtttacca ttttttaaaa aatagagaaa aaggagaaaa
    33901 gagatgactg aaaaaagact ggcctgggat gagtattttg cagcccaagc cctactaatt
    33961 gcgaatcgtt ccacttgtaa acgtgctaaa gtgggcgcga ttctggtaaa agataataag
    34021 gttatttcca ctggttacaa tggttcggtg tcagggactg agcattgtat tgatcacgaa
    34081 tgtttggtca ttgaaggcca ctgtgttcgc acccttcacg ctgaggtcaa tgctatcctt
    34141 caaggtgctg agcgtggtgt tcccaaaggc tttacagcct atgtaaccca ttttccttgt
    34201 ctcaactgta caaaacaatt gcttcaggtc ggctgcaagc gtgtggttta tatcaaccag
    34261 taccgaatgg acgactacgc ccaatacctt tatcaagaaa aagggacaga attgacccat
    34321 ttaccacttg agacagtaca gacagctctt aaagaggctg atctaatgta aaaattatca
    34381 aaaataaatg gtttagaaag atttttaaac cgttttttgg tataataaga agaataaatt
    34441 gaaagaagga attccaaaaa tgggaaaaat tgaagttatt aatcacccac tgattcaaca
    34501 caaattgtca atcttgcgtc gtacagatac ttctacaaaa gcttttcgtg agctagtaga
    34561 tgagattgca atgttgatgg ggtatgaagt acttcgtgat cttccactag aagatgtgga
    34621 aatcgaaaca ccaattacaa aaacagttca aaaacaattg gcaggtaaga aattggccat
    34681 cgtcccaatc ttgcgtgcag gtatcgggat ggttgatggt ctcttgagct tggttccagc
    34741 tgctaaagtt ggccacatcg gtatgtaccg tgatgaagaa acacttcaac cagttgaata
    34801 cttggtgaaa ttgcctgagg acattgacca acgtcaaatt tttgtagtag acccaatgtt
    34861 ggcaacaggt ggctcagcaa tcttggctgt tgattctctt aaaaaacgtg gcgcatcaaa
    34921 tatcaaattt gtctgccttg tatctgctcc agagggtgta aaagcccttc aagaagctca
    34981 tccagatgta gaaatcttta cagcagcctt ggatgaacgt ttgaatgaac acggttatat
    35041 cgttccaggt cttggagatg ctggagaccg cttgttcggt acaaaataag atcgaaaaga
    35101 agaatgactt ggaaaagtat ttctagtcac gaaaggaggt tgggtttttg tttctgtcta
    35161 atgaaagcag agcaaaaatt tgaccttttt tgaccaagat attataatag tcttatcttc
    35221 agtcatttga ccaacaaaat taaaactcaa aaggagaaat gaatgattcc tgtagttatt
    35281 gaacaaacaa gccgtggaga acgttcttac gatatttact cacgtcttct caaagaccgc
    35341 atcattatgc tgacaggtcc ggttgaagac aatatggcta actctgttat tgcccaattg
    35401 cttttcttgg atgcccaaga tagtacgaaa gatatttacc tttatgtcaa tacaccaggt
    35461 ggttctgttt cagctggttt ggcaatcgta gataccatga actttatcaa ggcagatgtc
    35521 caaaccattg ttatgggaat ggctgcatct atggggactg tcatcgcatc aagtggagca
    35581 aaaggcaaac gtttcatgct tccaaatgct gaatacatga ttcaccaacc aatgggcggt
    35641 acaggtggtg gtacccaaca aactgatatg gctatcgctg cagaacactt gctcaaaact
    35701 cgtaatacct tggaaaaaat cttggctgaa aattcaggtc agtcaatgga aaaagtccat
    35761 gcagatgcag aacgtgataa ctggatgagc gcccaggaaa cacttgaata tggctttatt
    35821 gatgaaatta tggccaacaa ttcattgaac taatgatgat agaaggcaaa ctcgactggg
    35881 tttgcttttt ttggtataat agggagagat ttcttagaaa gaggatttat catgtttgaa
    35941 aaagtcaatc gctctggctt gattatctat ctttactata atcgtgatgc caaaaaactg
    36001 caggattatg gagatattac ctatcattcc aagaaacatc gttacttaca actctatgtt
    36061 ccaactcaag aagtggagca attggtcgga cgcttgagca aggaaaaatt tattaaaaaa
    36121 gttagggttt gtcatatcca agagttggaa acaccctttg tgggcaatct ttatcgatag
    36181 gaaaacgtta tcatcgaaaa agttcaagga aaacattgac aattttctga taattcggta
    36241 tatttttaac agactgttta agaaataagg agacaaaaag atgaagaaaa aatttgccct
    36301 atcgtttgtg gcgcttgcaa gtgtagcact tcttgcagcc tgtggagaag tgaagtctgg
    36361 agcagtcaac actgctggta actcagtaga ggaaaagaca attaaaatcg ggtttaactt
    36421 tgaagaatca ggttctttag ctgcatacgg aacagctgaa caaaaaggtg cccaattggc
    36481 tgttgatgaa atcaatgccg caggtggtat cgatggaaaa caaatcgaag tagtcgataa
    36541 agataataag tctgaaacag ctgaggctgc ttcagttaca actaaccttg taacccaatc
    36601 taaagtatca gcagtcgtag gacctgcgac atctggtgcg actgcagctg cggtagcgaa
    36661 cgctacaaaa gcaggtgttc cattgatctc accaagtgcg actcaagatg gattgactaa
    36721 aggtcaagat tacctcttta ttggaacttt ccaagatagc ttccaaggaa aaattatctc
    36781 aaactatgtt tctgaaaaat taaatgctaa gaaagttgtt ctttacactg acaatgccag
    36841 tgactatgct aaagggattg ccaaatcttt ccgcgagtca tacaagggtg aaatcgttgc
    36901 agatgaaact ttcgtagcag gtgacacaga ctttcaagca gcccttacaa aaatgaaagg
    36961 gaaagacttt gatgctatcg ttgttcctgg ttactataat gaggctggta agattgtaaa
    37021 ccaagcgcgt ggcatgggaa ttgacaaacc aatcgttggt ggtgatggat tcaacggtga
    37081 ggagtttgta caacaagcaa ctgctgaaaa agcatcaaac atctacttta tctcaggctt
    37141 ctcaactact gtagaagttt cagctaaagc taaagccttc cttgacgctt accgtgctaa
    37201 gtacaatgaa gagccttcaa catttgcagc cttggcttat gattcagttc accttgtagc
    37261 aaacgcagca aaaggtgcta aaaattcagg tgaaatcaag gataaccttg ctaaaacaaa
    37321 agattttgaa ggtgtaactg gtcaaacaag cttcgatgca gaccacaaca cagtcaaaac
    37381 tgcttacatg atgaccatga acaatggtaa agttgaagca gcagaagttg taaaaccata
    37441 atagaaaaat gttgaaatag ggaatgagcc tttgactcac tccctgtttc gatatttaat
    37501 actcttcgaa aatctcttca aactgcgtca acgtcgcctt ggattatata tgtgactgac
    37561 ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag caacctgcgg ctagtttcct
    37621 agtttgctct ttgattttca ttgagtataa gaacctatca aaaagtgagg gaaacccctc
    37681 ggaattataa atagaaagag tgaatcttat gctccaacaa ctcgtaaatg gtttgattct
    37741 aggtagtgtt tacgcgctgt tagccctagg atataccatg gtttacggaa ttatcaagct
    37801 catcaacttc gcccatggtg atatttatat gatgggagcc tttatcggtt atttcttgat
    37861 caattctttc caaatgaatt tctttgtagc gcttattgta gctatgctag cgacagctat
    37921 tcttggtgtc gtgattgagt ttcttgctta ccgacctttg cgccactcta ctcgtattgc
    37981 tgttttgatt acggctattg gggtttcttt cctattggag tatggaatgg tctatctggt
    38041 tggtgccaat acccgtgcct tccctcaagc gattcaaaca gttcgatatg atttgggacc
    38101 aattagctta acaaatgtgc agttaatgat tttggccatt tccttgattt tgatgatttt
    38161 gttacaagtc attgtccaaa agactaagat ggggaaagcc atgcgtgcag tatcagtaga
    38221 tagcgacgcg gcgcaattga tggggatcaa tgtaaaccgt acgattagct ttaccttcgc
    38281 tttgggttct gctcttgcgg gtgcggctgg tgttctgatt gctctttatt ataactctct
    38341 tgagcctttg atgggggtta ctccaggtct taaatctttc gttgccgcag tacttggtgg
    38401 tatcggaatt attcctggtg ctgctcttgg tggctttgtg attggtctat tggaaacctt
    38461 tgcgacagcc tttgggatgt cagatttccg tgatgccatt gtttatggaa tcttgttgtt
    38521 gatcttgatt gtccgcccag ctggtatcct tggtaagaat gtgaaagaga aggtgtaaac
    38581 gatgaaggaa aatttaaaag ttaatattct atggttactc cttttgttag ctggctatag
    38641 cttgattagt gtactggttt cagtcggagt acttaatcta ttctatgtac agattttaca
    38701 acaaattgga attaatatta ttttggctgt tggtctcaac ttaatcgttg gtttttcagg
    38761 acaattttca cttggtcatg ctggtttcat ggcgattggt gcctatgcag cagctattat
    38821 tggttctaaa tcaccaacct acggtgcctt ctttggagct atgcttgtag gggctttgct
    38881 ttcaggagca gttgccttac ttgtcggcat tccaaccttg cgcttgaagg gggactatct
    38941 tgcggtagca actctgggtg tttctgaaat tatccgtatc tttatcatca atggtggaag
    39001 tcttacaaat ggtgcggcag gtatcttagg gattcctaac tttacaactt ggcaaatggt
    39061 ttacttcttt gtcgtgatta caaccattgc aaccttgaac ttcttgcgta gcccaattgg
    39121 ccgttcaacc ctctctgttc gtgaagatga aatcgctgct gagtcagttg gggttaatac
    39181 gactaaaatt aaaatcatcg cttttgtctt tggtgccatt actgcaagta ttgctgggtc
    39241 acttcaggca ggatttatcg ggtctgttgt accgaaagat tacaccttca tcaactcaat
    39301 caacgttttg attattgttg tatttggtgg actcggttcc attacaggtg cgattgtttc
    39361 ggctattgtt ctgggaattt tgaatatgct tctccaagat gttgctagtg tgcgtatgat
    39421 tatttacgct ttggccttgg tattggtaat gattttcaga ccaggtggac tccttggaac
    39481 gtgggaactg agcctatcac gtttctttaa aaaatctaag aaggaggaac aaaactaatg
    39541 gcattacttg aagtaaaaca gttaaccaaa cattttggtg gtctaacagc tgttggagat
    39601 gtgactcttg aattgaacga aggggaactg gttggattaa tcggtccaaa cggagctggg
    39661 aaaaccaccc ttttcaacct tttgaccggt gtttatgaac caagcgaggg aacagtaacc
    39721 ctagatggtc accttttgaa tgggaaatca ccttataaga ttgcctcttt gggacttgga
    39781 cgtactttcc aaaatatccg tctctttaaa gatttaacag ttttagacaa tgttttgatt
    39841 gcttttggaa accatcacaa acaacatgtt tttactagtt tcttacgctt accagctttt
    39901 tacaagagtg aaaaagaatt aaaggctaaa gctttggaat tgttgaaaat ctttgattta
    39961 gatggtgatg cagagactct tgctaaaaat ctttcctacg gacaacaacg tcgtttggaa
    40021 attgttcgtg cccttgctac ggaacctaaa attctcttct tagatgaacc agcagcaggt
    40081 atgaacccac aggaaacagc cgaattgact gagttaattc gtcgtatcaa agatgaattt
    40141 aagattacaa tcatgttgat tgaacacgat atgaatctgg tcatggaagt aacagaacgt
    40201 atctacgtac ttgaatatgg ccgtttaatt gctcaaggaa ctccagacga aattaagacc
    40261 aataaacgcg ttatcgaagc ttatctagga ggtgaagcct aatgtctatg ttaaaagttg
    40321 aaaatctttc tgtgcattac ggtatgatcc aagcagtccg tgatgtaagc tttgaagtta
    40381 atgaaggaga agttgtttcc cttatcggtg ccaacggtgc aggtaagaca actattcttc
    40441 gcaccttgtc aggtttggtt cgaccaagtt caggaaagat tgaattttta ggtcaagaaa
    40501 tccaaaaaat gccagctcag aaaattgtgg caggtggtct ttcacaagtt ccagaaggac
    40561 gccacgtctt tcctggcttg actgttatgg aaaatcttga aatgggagct ttcttaaaga
    40621 aaaatcgtga agaaaatcaa gctaacttga agaaggtttt ctcacgcttt cctcgtcttg
    40681 aagaacgtaa gaaccaagat gcagctactc tttcaggagg ggaacaacaa atgcttgcca
    40741 tgggacgcgc tcttatgtca acaccaaaac ttcttctttt agatgaacca tcaatgggac
    40801 ttgccccaat cttcatccaa gagatttttg atatcattca agatattcag aagcaaggaa
    40861 caaccgtcct cttgattgaa caaaatgcca ataaagcact tgcaatctct gaccgaggat
    40921 atgtactgga aacagggaaa atcgtcctat caggaacagg aaaagaactc gcctcatcag
    40981 aagaagtcag aaaagcatat ctaggtagct aaaacaatcc agtggattgt tttagtcggc
    41041 agatgaagat tacgaagtaa tcatcattat agtctgggag actagtttag gttgcagata
    41101 aagattgcga agcaatcatc aaatccagag gattgtttta gccggcagat ggagattacg
    41161 aagtaatcat caatatagtc ctggggacct ttttagtcgg tggatagaga ttgcaaacaa
    41221 atatgcatct acattgaaag cttaatttct aataattgaa aaaatcgaat gaaaaatttc
    41281 ttaccttcat tcacagagct ctatttcaga gctctttttg ctagcttatt catacttttt
    41341 tgaatttcga aaaagaaatg taagcgtttg atagatttac aaaaagattg tataatgggg
    41401 ataagaatag aaaaggagaa gtctcatggc agttaaagat tttatgaccc gcaaggtagt
    41461 ttatattagt ccagatacaa cagtatctca tgcagcagat ttgatgagag agcaagaatt
    41521 gcatcgcttg cctgttatcg aaaatgatca attggttggt ttggtgactg agggaaccat
    41581 tgcacaagca agtccatcta aagcaacaag tctttctatc tatgagatga attatcttct
    41641 gaataagaca aaagtaaaag atgtcatgat tcgcgatgtt gtcactgtct caggctatgc
    41701 tagtctagaa gatgcaactt atctgatgtt gaaaaataag attggtattc tccctgtcgt
    41761 agataaccat caagtatacg gagttattac tgaccgtgac gttttccaag cctttcttga
    41821 aattgcaggt tatggcgaag aagggattcg tgtacgcttt gttacagaag atgaagttgg
    41881 tgttcttgga aaaattgttt ctttgattgt agaagaaaat ttgaatatct cccatacagt
    41941 caatattccg cgtaaggatg gtaaggtgat tatcgaagtg caaatcgatg gatcaattga
    42001 tttaccagcc ttgaaagaaa aatttgaagc aaatggtatt caagtggaag aaatcgttcg
    42061 cacttcagca aaagtcttgt aagaagggaa gcccaaaggc ttcttttttc atgaaaaggg
    42121 gattagagca aaagatggaa agaaatgata aaatatgcta taatgaaata atgtaaaaaa
    42181 ggagtattta tggacatttc agtaattcgt cagaaaattg acgcaaatcg tgaaaaatta
    42241 gcttctttca gggggtctct ttgacctcga agggctagag gaagagattg ccatcttgga
    42301 aaacaagatg acagaacctg atttttggaa cgataatatt gcggcccaaa aaatgtcgca
    42361 agaattaaat gaattaaaaa acacttacaa taccttccat aagatggaag agttgcagga
    42421 tgaagtcgaa attttattgg attttttggc tgaagacgag tcagtgcatg atgaactggt
    42481 agcgcagtta gccgaacttg ataagataat gaccagctac gagatgactc tactcttgtc
    42541 agaaccttat gaccacaaca atgccatctt ggaaatccat ccaggttctg gtggtactga
    42601 ggcgcaggac tggggtgata tgttgcttcg tatgtatact cgttatggta atgctaaagg
    42661 ctttaaagtg gaagtgttgg attaccaagc aggtgatgag gctggtatta agtcggtaac
    42721 tttatcattt gaagggccta atgcctatgg tctcctcaag tcagaaatgg gtgttcaccg
    42781 cttagtgcga atctcaccat ttgactctgc caaacgtcgc catacctctt tcacatctgt
    42841 agaagtgatg ccagaattgg atgatactat tgaagtggaa atccgtgaag atgatatcaa
    42901 gatggatacc ttccgttcag gtggtgccgg tggacaaaac gtcaataagg tttcaacagg
    42961 tgtacgttta acctacattc caactggaat tgttgtccaa tcaacagtgg atcgtaccca
    43021 gtatggaaat agagatcgcg ccatgaagat gttgcaggct aagctctatc aaatggagca
    43081 agagaagaag gctgcggagg tagattctct caaaggtgag aaaaaggaga tcacttgggg
    43141 aagtcaaatc cgttcttatg tcttcacgcc ttatactatg gtaaaagatc accgaactag
    43201 ctatgaggtt gctcaggtag ataaggttat ggatggagac ctagatggtt ttatcgatgc
    43261 ttatctcaag tggcgaatta gctaagatag aaaggaactc acatgtcaat tattgaaatg
    43321 agagatgtcg ttaaaaaata cgacaacgga acgactgctc tacgcggtgt ttcggttagc
    43381 gttcaaccgg gggaatttgc ttacatcgta ggaccttcag gagcagggaa gtcaactttt
    43441 attcgttctc tgtatcgtga agtaaaaatc gataaaggaa gtctatcagt tgctggtttt
    43501 aatctggtta agatcaaaaa gaaagatgtc ccgcttctac gtcgtagtgt tggggttgtc
    43561 ttccaagatt ataaattgtt accaaagaaa actgtctatg aaaatattgc ttacgctatg
    43621 gaagtaatcg gggaaaatcg ccgtaatatc aaaagacgag tgatggaagt tttggacttg
    43681 gttggattga agcataaggt tcgttctttc ccaaatgaac tctcaggtgg ggagcaacag
    43741 cggattgcga ttgcgcgtgc aattgtaaat aatcccaaag tattgatagc tgatgagcca
    43801 acaggaaatc tggatccgga taattcatgg gaaattatga atctcttgga acggattaac
    43861 ctacaaggaa caactatttt gatggcgact cataatagcc agattgtaaa taccttgcgc
    43921 caccgtgtca ttgccattga aaatggccgt gtcgttcgtg acgaatcaaa aggagagtat
    43981 ggatacgatg attagtagat tttttcgcca tttatttgaa gccttaaaaa gtttgaaacg
    44041 aaatggttgg atgacagtag ctgctgtcag ttcagtcatg attactttga ccttggtggc
    44101 aatatttgca tctgttattt tcaatacagc gaaactagct acagatattg aaaataatgt
    44161 ccgtgtagta gtttatatcc gaaaggatgt ggaagataat agtcagacaa ttgaaaaaga
    44221 aggtcaaact gttacaaata atgactacca caaggtatat gattctttga agaacatgtc
    44281 tacggttaaa agtgttacct tttcaagtaa agaagaacaa tatgaaaaat taaccgagat
    44341 aatgggagat aactggaaaa tctttgaagg agatgccaat cctctctatg atgcctatat
    44401 tgtagaggca aacactccaa atgatgtaaa aactatagcc gaagatgcta aaaaaattga
    44461 aggtgtctct gaggttcaag atggcggtgc caatacagaa agactcttca agttagcttc
    44521 atttatccgt gtttggggac tagggattgc tgctttgtta atttttatcg cagttttctt
    44581 gatttcaaat accattcgta ttaccattat ttcccgcagt cgcgaaattc aaatcatgcg
    44641 cttggtcgga gctaaaaaca gttatatccg tggaccgttc ttgttagaag gagcctttat
    44701 cggtttattg ggagctatcg caccatctgt tttggtcttt attgtttatc aaattgttta
    44761 ccaatctgtc aacaaatcgt tggtagggca aaatctatcc atgattagtc cagatttatt
    44821 tagtccgttg atgattgccc tactatttgt gattggggtt ttcattggtt cattgggatc
    44881 aggaatatcc atgcgccgat tcttgaagat ttaggtaaaa tagctgcttt tatgaggaga
    44941 ttgtaaaatc tccttttttg ctacaagagt ttttgaaaag agatgcgtag aagaaaagag
    45001 cttccaaaga agtcctctag agaagacttc ttgatggcta atttgaactt gaaatttgac
    45061 tcactagaaa ttttttagaa aaaagtgtaa tttttttcta aaagccttta caaaaaaaat
    45121 taaagtggta taattaaatt atagaaggtg caaacgtttt cgtaaaacgt ttgcctaaat
    45181 aaaaataaag gagatttgaa tgatgaaaga tacattcaaa aatgtcttgt ctttcgaatt
    45241 ttggcaaaaa ttcggtaagg ctttgatggt agttatcgcg gttatgccgg ctgctggttt
    45301 gatgatttca atcggtaagt ctatcgtgat gattaaccca acctttacac cacttgtcat
    45361 cacaggtgga attcttgagc aaatcggttg gggggttatc ggtaaccttc acattttgtt
    45421 tgccctagcc attggaggaa gctgggctaa agaacgtgct ggtggtgctt tcgccgctgg
    45481 tcttgccttc atcttgatta accgtatcac tggtacaatc tttggtgtat caggcgatat
    45541 gttgaaaaat ccagatgcta tggtaactac tttctttggt ggtttaatca aagttgctga
    45601 ttactttatc agtgttcttg aagctccagc cttgaacatg ggggtattcg tagggattat
    45661 ctcaggtttt gtaggggcaa ctgcttacaa caaatactac aacttccgta aacttcctga
    45721 tgcactttca ttcttcaacg ggaaacgttt cgtaccattt gtagttattc ttcgttcagc
    45781 aatcgctgca attctacttg ctgctttctg gccagtagtt caaacaggta tcaataactt
    45841 cggtatctgg attgccaact cacaagaaac tgctccaatt cttgcaccat tcttgtatgg
    45901 tactttggaa cgtttgctct tgccatttgg tcttcaccac atgttgacta tcccaatgaa
    45961 ctacacagct cttggtggta cttatgacat tttaactggt gcagctaaag gtactcaagt
    46021 attcggtcaa gacccactat ggcttgcatg ggtaacagac cttgtaaacc ttaaaggtac
    46081 tgatgctagt caatatcaac acttgttaga tacagtacat ccagctcgtt tcaaagttgg
    46141 acaaatgatc ggttcattcg gtatcttgat gggtgtgatt gttgctatct accgtaatgt
    46201 tgatgctgac aagaaacata aatacaaagg tatgatgatt gcaacagctc ttgcaacatt
    46261 cttgacaggg gttactgaac caatcgaata catgttcatg ttcatcgcaa cacctatgta
    46321 tcttgtttac tcacttgttc aaggtgctgc cttcgctatg gctgacgtcg taaacctacg
    46381 tatgcactca ttcggttcaa tcgagttctt gactcgtaca cctattgcaa tcagtgctgg
    46441 tattggtatg gatatcgtta acttcgtttg ggtaactgtt ctctttgctg taatcatgta
    46501 ctttatcgca aacttcatga ttcaaaaatt caactacgca actccagggc gcaacggaaa
    46561 ctacgaaact gctgaaggtt cagaagaaac cagcagcgaa gtgaaagttg cagcaggctc
    46621 tcaagctgta aacattatca accttcttgg tggacgtgta aacatcgttg atgttgatgc
    46681 atgtatgact cgtcttcgtg taactgttaa agatgcagat aaagtaggaa atgcagagca
    46741 atggaaagca gaaggagcta tgggtcttgt gatgaaagga caaggggttc aagctatcta
    46801 cggtccaaaa gctgacattt tgaaatctga tatccaagat atccttgatt caggtgaaat
    46861 cattcctgaa actcttccaa gccaaatgac tgaagcacaa caaaacactg ttcacttcaa
    46921 agatcttact gaggaagttt actcagtagc agacggtcaa gttgttggtt tggaacaagt
    46981 aaaggatcca gtatttgctc aaaaaatgat gggtgatgga tttgcagtag aacctgcaaa
    47041 tggaaacatt gtatctccag tttcaggtac tgtgtcaagc atcttcccaa caaaacatgc
    47101 ttttggtatt gtgacggaag caggtcttga agtattggtt cacattggtt tggacacagt
    47161 aagtcttgaa ggtaaaccat ttacagttca tgttgctgaa ggacaaaaag ttgcagcagg
    47221 agatctcctt gtcacagctg acttggatgc tatccgtgca gcaggacgtg aaacttcaac
    47281 agtagttgtc ttcacaaatg gtgatgcaat taaatcagtt aaattagaaa aaacaggttc
    47341 tcttgcagct aaaacagcag ttgctaaagt agaattgtaa tatacttgag gttggaagct
    47401 gtattccaac ctcttatttt gggagaaaag aatgaaattt ttaacactca atactcacag
    47461 ttggatggag aaagaagcag aggaaaaatt ccagattttg cttgaagata ttcttgaaaa
    47521 ggactatgat ttgatttgtt tccaagaaat caatcaggag atgacctcgt cagaggtgga
    47581 ggttaatgac ctttatcaag ctttgccagc agctgagcct attcaccaag accattatgt
    47641 tagactcttg gttgaaaagt tgttagagca agggaaaaat tactactgga cctgggctta
    47701 taaccatatc ggctatgacc gctaccacga aggtgtggct atcttgtcta aaacacctat
    47761 tgaagccaga gaaattttgg tttcagatgt ggatgatcca acagactatc atactcgccg
    47821 tgttgcccta gctgaaactg tagtcgatgg caaggagcta gcagttgcca gtgttcatct
    47881 ctcttggtgg gataaaggtt tccaagaaga atgggcacga tttgaggctg tcttgaaaaa
    47941 attgaacaag ccacttttac tagctggaga ttttaacaac ccagcaggtc aggaaggtta
    48001 ccaagctatt ttagctagtc cattaggctt acaagacgca tttgaagttg ctcaagagaa
    48061 aagtggtagc tatactgttc cgcctgaaat tgatggctgg aaagggaaca ctgaacccct
    48121 tcgaatcgat tatgtcttta ctaccaaaga gttagcggtg gaaaatttac atgtcgtatt
    48181 tgatggtaac aagagtccac aagtgagtga tcactatggc ttgaatgcta tattaaactg
    48241 gaaataataa ctgaaaagag gttggaacta taaaattcca gccttttctt actagagaag
    48301 ctactggaaa tagcctaaat aagtgagact actgtaatgg aataaaatat ggtataattg
    48361 ataagataga tagaatcgag gatgttatgt catttacgaa atttcaattt aaaaactata
    48421 ttagagaagc cttgaaggag ttaaaattta caactccaac agaggtgcaa gacaagttga
    48481 ttcctattgt tttggcaggt cgtgacctag taggagaatc aaaaacaggt tcaggtaaga
    48541 ctcatacttt cttgttaccg attttccagc aattagatga agctagcgat agtgtacaag
    48601 cagtgattac tgcaccgagt cgtgagttgg ctactcaaat ttaccaagta gcgcgtcaga
    48661 tttcagctca ctcagatgtc gaagttcgtg tggttaatta tgtgggtggt acggataagg
    48721 ctcgccagat tgagaaattg gcaagcaatc agcctcatat tgttattgga acaccaggcc
    48781 gtatctacga cttggttaaa tctggtgatt tagctattca taaagccaag acatttgttg
    48841 ttgatgaagc agatatgacc ttggatatgg gattcttgga aactgttgat aagattgctg
    48901 gcagtcttcc aaaagacttg caattcatgg tcttctcagc gactatccca caaaaactgc
    48961 aaccattctt gaaaaaatac ttatcaaatc ctgttatgga gaaaattaag actaaaacgg
    49021 ttatttctga caccattgat aattggttga tttcgaccaa gggacatgat aagaatgctc
    49081 aaatttactg gttgactcag ttgatgcagc cgtatttggc aatgattttt gttaacacta
    49141 aaacgcgtgc tgatgaattg cattcatatc tgacttctca aggtttgaag gttgcaaaaa
    49201 tccatggcga tattgcccct cgtgaacgca agcgaatcat gaatcaggtg caaaatctgg
    49261 attttgagta tattgtcgca acagatttag cagcgcgtgg gattgacatt gaaggtgtca
    49321 gccatgtcat caatgatgcc attccgcaag acttatcttt ttttgttcac cgtgttggtc
    49381 gtactggacg aaatggccta ccaggtacag ctattaccct ttatcagcca agtgatgact
    49441 cggatatccg tgagttggag aaattgggaa tcaagtttag tcctaagatg gtcaaagacg
    49501 gggaatttca agatacctat gaccgtgatc gtcgtgccaa ccgtgagaaa aaacaagata
    49561 aacttgatat cgaaatgatt ggtttggtta aaaagaaaaa gaaaaaagtc aaaccgggtt
    49621 ataagaagaa aattcaatgg gcggttgatg aaaagcgccg taaaaccaag cgtgctgaaa
    49681 atcgcgctcg cggtcgtgca gagcgtaaag ctaaacgtca aacattttaa tagaaattgt
    49741 tggagtactg agctccaact ttttgcttta tgagaacgaa ctatctaaac cgaaacacta
    49801 cattaaagac tgcaaattgc gattaaaaat ggtataatga taaagttata tagtcccgat
    49861 aagatggtag gtatttatta cgaagagttt tcctatcagt actttgtaac tctataacaa
    49921 tattttttaa ggggggacat ttttatgtca gaacgtaaat tattcacgtc tgaatctgta
    49981 tctgaggggc atccggataa gattgcagac caaatttcag atgcgatttt ggatgctatt
    50041 ttagcaaagg atccagaggc gcacgttgct gctgaaacag ctgtatatac tggttctgtc
    50101 cacgtttttg gtgaaatttc tacaaatgcc tatgtggata ttaaccgtgt ggttcgtgat
    50161 accattgcag agattggtta taccaataca gaatatggat tttctgctga gacggtggga
    50221 gtacacccat ctttggtgga acaatctcct gacatcgctc aaggtgttaa cgaagccttg
    50281 gaggttcgtg gaaatgctga tcaagatcca ctggacttga ttggagcagg tgaccaaggg
    50341 ctcatgtttg gatttgcagt agatgaaaca gaagagctta tgccattgcc aattgcactc
    50401 agtcataaat tggttcgtcg tctggcagaa cttcgtaagt ctggagaaat tagctatctc
    50461 cgtccagatg caaaatcaca agttacagtt gagtacgatg aaaatgaccg tccggtacgt
    50521 gtagatacag tcgttatttc tactcagcat gatccagagg ccactaatga acaaatccat
    50581 caagatgtga ttgacaaggt catcaaagaa gttattccat cttcttatct tgatgataag
    50641 acaaaattct ttatcaatcc gacaggtcgt tttgtaatcg gtggtcctca aggggactca
    50701 ggtttgactg gtcgtaagat tattgtagat acttatggtg gctactctcg tcatggtggt
    50761 ggtgccttct ctggtaaaga tgcgactaag gtggatcgtt cagcctctta tgcggctcgc
    50821 tatattgcca agaatatcgt tgcagcaggc cttgctaaga aggcagaagt gcagttggcc
    50881 tatgctatcg gtgttgcgca acctgtttct gttcgtatcg atactttcgg tacaggaaca
    50941 gtagctgaaa gtcaacttga aaaagcggct cgtcaaatct ttgaccttcg ccctgcaggg
    51001 attatccaaa tgctggacct caagcgtcca atttaccgtc aaacatcggc ttacggtcac
    51061 atgggacgta cagatattga tcttccatgg gaacgtttgg ataaggtaga tgctttgaaa
    51121 gaagcagtaa aataagattt taagagggga acgtcctctc ttttttatag tttttaacta
    51181 tactgggata ctgttctgaa aatccatttt gcgaaagtag agatttacat gtatagtaga
    51241 ttgaaactag aatagtacac ctcaacttct aaaacattgt tagcaatcaa tttgactgtc
    51301 ctgatcgatt tctcctgttc ttgtttcatt ttactatatt tctttaaaaa tgataaaggt
    51361 taagatttct cctcgtaata gataatcttg gggatatttc aatccaaagt tttattcgtt
    51421 atcacttgac tattgcaagg ttttctagag caacagagtc atggaatgga ctcatggttg
    51481 agatttctcc ttgttgcttg gacttcattc aaaagtctgt tacccaagcc ttgttcaaac
    51541 ttctaataca ctagctgttt ccatagcatg acttctgtac tagactttct tttccgaata
    51601 aatagataga accacagaat ctagtaaacc tagaattaaa attatggtat aatattagca
    51661 ataaaagaaa tctggaggat tagaatcatg gtatcaacga aaacacaaat tgctggtttt
    51721 gagtttgaca attgcttgat gaatgcagca ggtgtggctt gtatgacgat agaggagtta
    51781 gaagaggtca aaaactcagc ggcaggaacc tttgttacta agacagcgac cttggacttc
    51841 cgtcagggga atcctgagcc acgctaccaa gatgttccac ttggttccat caactctatg
    51901 ggcttgccaa ataatggctt agactattat ttggattatc ttttagattt gcaggaaaaa
    51961 gagtcgaacc gaactttctt cttatctctg gtcggcatgt ctccagagga aacccatact
    52021 attttgaaaa aagtccaaga gagtgatttt cgtggtctga ctgagctaaa tctttcctgt
    52081 ccaaatgttc caggtaaacc tcagattgcc tatgattttg agacaacaga ccggattttg
    52141 gcagaagtgt ttgcttactt caccaaacct cttggaatta aattgccacc ttattttgat
    52201 attgttcact ttgatcaagc ggcagctatt ttcaacaaat atccgctcaa gtttgtcaac
    52261 tgcgttaact ctatcggaaa cggcctctat atagaagacg aatctgtcgt tattcggcct
    52321 aagaatggtt ttggtggaat tggtggagaa tacatcaaac cgactgctct agccaatgtt
    52381 cacgcctttt atcaacgttt aaatcctcaa atccaaatta tcggaacagg tggcgttctg
    52441 actggtcgag atgcctttga acacatcctc tgtggagcaa gtatggtgca ggtgggaacg
    52501 acccttcaca aagaaggcgt cagtgctttt gaccgcatta ccaatgaact gaaagcaatc
    52561 atggtggaaa aaggctacga gagcttagaa gatttccgtg ggaaattgcg ctatattgac
    52621 taaattaaat cgaaaaatct gaagaaagga gagtcgatgc tagccattga agaaagtcag
    52681 aagttgactt tatcaaattt accgagcctg agcctattta cagggacaga tcagggtcag
    52741 tttgaagtga tgaagagtca aatgttgaaa cagattgggt atgattctgc tgacctcaac
    52801 tttgcctact ttgatatgaa agaagtagtt tacaaggatg tggaactgga gttggtcagc
    52861 cttcctttct ttgcggatga gaaaatcgtg atattagatt attttatgga tatcacgact
    52921 gctaagaaac gctttttgac agatgatgag cttaagtcat ttgaggaata ccttgacaat
    52981 ccttctccaa caactaagtt gataatcttt gcagaaggaa agctggatag caaaagacgg
    53041 ttagtcaaat tacttaagcg tgatgccaag gtcttcgatg cagtagaagt aaaagaacaa
    53101 gaattgcgcc agtatttcca aaagtggagt cagaaacaag gtctgcagtt taccaatcat
    53161 tcttttgaaa atctcctcat caagtcgggg tttcaattta gcgaaatcca gaaaaatctt
    53221 ctctttttac agtcctataa ggcggattct gttatcgagg aagaggatat tgttaacgca
    53281 attcccaaga ccttgcagga caatattttt gatttaactc agtttattct gactaaaaag
    53341 atggatcagg cgcgcgattt ggtgagagac ttgaccttgc aaggggaaga tgaaatcaaa
    53401 ctgattgcag tcatgctggg acaatttcgg acttttactc aggtgaagat tttggcggag
    53461 tctggccaaa cagaatcgca gattgcaagt agtttaggta gttatctggg acgtaaccca
    53521 aatccttatc aaatcaagtt tgcattaaga gattcgagag gactttcttt gagctttctg
    53581 aagcaagcta tttcctattt gattgagaca gactatcaga ttaagacagg tctttatgaa
    53641 aaaggtttcc tttttgaaaa ggcactctta cagattgcta gtcaggtcaa ttgacatttg
    53701 ttgaaactac aacccgcgtc aggattatct tgtcgtgggt ttcttgctga tttgcttatt
    53761 ttattagaaa gtatgtcagt gatttcctta tctataagca aaaaacttga aaaaagtgaa
    53821 tgtttgcgtt atcattttca tatagaaaga aaaagaggta ttacagatgg ctattatctt
    53881 accagaactt ccatatgcat acgacgcttt ggaaccatac atcgatgcgg aaacaatgca
    53941 tttgcaccat gacaaacacc atcaaactta tgtcaacaat gccaatgcag ctttagaaaa
    54001 acaccctgaa atcggtgaag accttgaagc cttgcttgct gatgtagaat ctatcccagc
    54061 tgatatccgt caagcactta tcaacaatgg tggcggacac ttgaaccacg ctcttttctg
    54121 ggaattgatg actcccgaga aaacagctcc ttcagcagaa ctggcagcag caatcgatgc
    54181 aacatttggt tcatttgaag aattccaagc agccttcact gcagcagcaa caactcgttt
    54241 tggttcaggt tgggcatggt tggttgtcaa caaagaaggg aaacttgaag tgacttcaac
    54301 agcaaaccaa gacacaccaa tctcagaagg taaaaaacca atcttgggct tggacgtttg
    54361 ggaacatgct tactacgtga aataccgcaa cgtgcgtcct gactatatca aagctttctt
    54421 ttcagtaatc aactggaata aagtagatga attgtacgca gctgctaaat aatgatagtt
    54481 ggagggaaga attgttcttc tcttttttag gttataagat tctggtctga caaaatcgtc
    54541 agactttttt catttttatg agaaacgtgc taactgctag aaattatggt agaataaagt
    54601 attaagtaat cgtggaaaaa ggatatctat gcgaaaagaa attgcacctg aattatacaa
    54661 ctataacaag tttcctggtc cggagttcca tttacacggg gataaggtcg aaacggaagg
    54721 gatagctttt tccttggttg aaaatatcaa ggatgccttt gatgtgacga cttttaatca
    54781 gcgtttttca gaagtcttaa ccaagtttga ttatatcgtg ggggactgga gcaacgaaca
    54841 gcttcgccta cgaggttttt acaaggatga ccgaacagaa gaaaaacttg aaaaaatcag
    54901 tcgtttacaa gactaccttt tagagtattg tagttatggt tgtgcctatt ttgtcttaga
    54961 aaatgaagcc cctaagcgag catcatttga caagaaaatg cgtaagacgg aagaagaaac
    55021 accttctaga aaaggaaaga aaccgactca aaccaaacga aagtcgaatg cagataagaa
    55081 aaatagacgt cgtcagaaag accagcattc tcagaaagag gacaagggac aacgtcattt
    55141 tgtcattcgt cagaagtgag tagagaataa ggagaagaaa tgaaaccctc aattcatagt
    55201 ttgacacatc aaaccatgca ggaatgggta ttggagcagg gagaaaagaa attccgtgca
    55261 gatcaaatct gggaatggct ctaccgtaaa cgtgtgcagt catttgaaga aatgaccaac
    55321 ctttccaagg atttgattgc taagctcaat gaccagtttg tggtcaatcc cttgaaacaa
    55381 cgtattgtgc aagagtctgc tgatggtaca gtcaaatatc tctttgaatt gcccgacggt
    55441 atgttaattg agactgtact catgcgtcaa cactatggtt tatctgtctg tgtgaccact
    55501 caggtcggct gtaatatcgg ttgtaccttc tgtgcctctg gtttgattaa gaagcaacgt
    55561 gacctcaata acggtgaaat cgtagcgcaa atcatgctgg ttcagaaata ctttgctgag
    55621 cgtggtcagg atgaacgcgt cagccatatc gttgtcatgg gaatcggtga gccctttgat
    55681 aattacaaca atgtcttgaa tttctttcgt actatcaatg atgataaagg aacggctatc
    55741 ggtgctcgtc acatcatgat ttcaacctca ggtttggctc ataaaattcg tgactttgct
    55801 gatgaagggg ttcaggtcaa tcttgccgtg tctcttcacg cacccaacaa tgaacttcgt
    55861 tcaagtatca tgaaaattaa ccgtgccttt ccgattgaaa aactctttgc tgctattgaa
    55921 tactatattg agacaacaaa ccgtcgtgta acctttgaat atatcatgct taatgaagtc
    55981 aacgacggtg tagaacaagc cttggaattg gctgaattgc tcaagaacat caagaaattg
    56041 tcttatgtaa acttgattcc ttataaccca gttagtgagc atgaccaata tagccgtagt
    56101 cccaaagagc gcgtgttggc tttctatgat acgcttaaga aaaaaggggt caactgtgtg
    56161 gttcgtcaag agcatggtac agatattgac gcagcttgtg gacaattgcg ctctaacaca
    56221 atgaaacgtg accgccagaa ggcagtcgca gcggtaaatc cttaatgatg aagaagactt
    56281 ataatcatat tttggtctgg ggagtcattt tctatagcat ttgcattgtc tatttttgct
    56341 ttactcctca agaacaatct accgtgagag tgggaactcc aggtattcag catcttggac
    56401 gcctggtttt tcttttgact cctttcaatt ctctctggaa actgggcgaa gtgagtgaca
    56461 ttggacaatt atgttggatt tttttacaaa atgtcctcaa tgtcttctta ttttttcctc
    56521 tgattttcca actcctttat ctatttccaa atttgcggaa aacaaaaaag gtccttcttt
    56581 ttagttttct tgtgagtctt ggaatcgagt gtacgcaatt aatcttggac tttttctttg
    56641 atttcaatcg cgtctttgag attgatgatt tgtggaccaa tactttgggt ggctatctgg
    56701 cttggctcct ttataaacga ttacataaaa acaagataag gaattaaaat gagtatttta
    56761 gaagttaaaa atctgagtca cggttttggt gaccgtgcaa tttttgaaga tgtgtccttc
    56821 cgtctcctca agggagaaca tatcggcctg gtcggtgcca atggtgaagg aaaatcaacc
    56881 tttatgagta tcgtgactgg taaaatgctg ccagatgaag gaaaggttga gtggtccaaa
    56941 tatgtgacgg ctggttactt ggatcagcac tctgtccttg ctgaaagaca gtcggtgcgt
    57001 gatgttctcc gtacggcttt tgatgagctt ttcaaagctg aagctcgtat caatgacctc
    57061 tatatgaaaa tggctgaaga cggcgcggat gttgatgctc tcatggaaga agtaggagaa
    57121 cttcaagacc gtctggagag tcgtgatttc tataccttgg atgctaagat tgacgaagta
    57181 gcgcgtgctc ttggtgttat ggactttggc atggatacgg atgtaacttc tttgtcaggt
    57241 gggcaaagaa ccaaggtgct tttggcaaaa cttctccttg aaaagcctga tattttgctg
    57301 ttggacgagc cgaccaacta cttggatgct gagcatattg attggctcaa gcgctatctc
    57361 caaaactatg agaatgcctt tgttctcatt tcgcacgata ttccattcct caatgacgtt
    57421 atcaatattg tctatcatgt ggaaaatcaa cagctgacgc gttactctgg tgactactac
    57481 cagttccaag aagtttatgc tatgaagaaa tctcagctag aggcagccta cgaacgccag
    57541 cagaaagaga ttgcagacct caaggacttt gtggctcgta ataaagcccg tgttgcaact
    57601 cgtaatatgg ctatgtctcg tcaaaagaaa ttggataaga tggatattat cgaactccaa
    57661 agtgagaaac caaaaccatc ctttgatttc aaaccagctc gtacaccagg gcgctttatc
    57721 ttccaagcca agaacttgca aattggttac gaccgtcctc ttactaagcc tttaaatctt
    57781 accttcgaac gcaatcaaaa ggttgcgatt attggtgcta atggtattgg aaaaacaact
    57841 ctcttgaaga gtctcttggg cattatctcg ccaatcgctg gggaagtgga gcgtggagat
    57901 tatttagaac ttggttattt tgagcaggaa gtagaaggcg gtaatcgcca aactcctctt
    57961 gaagctgtct ggaatgcctt tcctgccctt aatcaagcag aagtccgtgc agcccttgcc
    58021 cgttgtggtt tgacaaccaa acatattgaa agccagattc aagtattatc agggggagag
    58081 caagccaagg ttcgtttctg tctcttgatg aatcgtgaaa acaacgtttt agtgctggac
    58141 gagccgacca accatttgga tgtggatgca aaggatgagc tcaaacgcgc tctcaaagaa
    58201 tataggggat ctatccttat ggtctgccac gagccagact tttatgaagg ctggatagac
    58261 caaatatggg attttaataa tttaacttaa gaatgagagt aaaagaaata cagtaccgaa
    58321 tgtggatact gtattttttt ggtttttaag atttaaaatc gtagtctttc accacttcga
    58381 tgctgtcgat tgtgatagca gtagttggct tgtctttttc atctttttcg gccttagcaa
    58441 tcttatccac aacatccata ccgtcaatca cttgaccaaa gactgggtgt ttgccatcta
    58501 gactagggtt tccaccttct ttgtaggctt cgataatttt ctgtggatac ttgcttgtag
    58561 ggagtttaga agaggtatct gtagagtttt ggttgatgaa gaactggctg ccattggtgt
    58621 ttggttgacc agtattagcc atagcaagag caccgcggat gttatacaaa taaggagtaa
    58681 tctcgttctt gaaaccagtt cctttgtctt tagtcttatc cttgtcatgc cagatggact
    58741 gaccacctgt accgtcccct tttggatctc cagtttggac cataaagcca tcgatgacac
    58801 ggtggaaggt aataccgtta tagtagcctt ctttggcgtg agtgaggaaa ttttcaaccg
    58861 ctagaggagc gagtttaggg aagagtttaa tgcgaatatc accttggctt gtgtggagaa
    58921 tcacttcggc ttcatcttca gcaacttcct tagatagttg tgggaaattg gcgttttcgt
    58981 ttgttaaagc atcgtttaac tccttggcag attgggcagc tactttggaa ctttcttcag
    59041 cagcaagact ggaatcaaca taatcatcac cacgcagact gcgttggacg ctgctacacc
    59101 cagctagggc tacagtagac agtaaaagaa gggttgctag ttttttcatt ctgatcctct
    59161 caaaaattca tttataccat tgtaccctaa aaggaagtgg atttcaaata ttagtagttt
    59221 acagaactgg cttagataat agttgggatt tcatcatcat cttgaaaatc ttcaacttct
    59281 tccccagtaa atggtttctg aaaagaactt agtataaaac gggcaattgg ttcaacaatt
    59341 aggaaattta gaggaagagc tgcaataaag tttacgaacc aggcgcttag ataggtattg
    59401 ggtgtgatag caatgccatt gtaaaaaagt ccatagaagg acatgaaagt gaccagctaa
    59461 ttcttcttct gaaaaatgct catgaagggc ttgatccagg tcgcaagatt tcattttaga
    59521 aagtccagta actcccttct tcttcaggat attctttttc atggtattat ttagatggtc
    59581 aagtgagtca aaagaagttt cgacaagagc ataccctttt tctaccagag tttttagatg
    59641 tttaggggca tcaataccat aagtgtactc aaagtatttt ggaaaccaga tcttaagaaa
    59701 gctcgtaaag ctagccagtt ctctaaacgc taagaactag ctacaacaca gcatttacaa
    59761 cacttcatgg ttcacaccat ggggtgtttt ttaatgattt taagcaaaat tcacacttaa
    59821 ttgaaagtta tttaaattag atgaaaattt attttttgaa aaagtgggaa aacattgatt
    59881 ctaagcgaat tttgaatcat attcgaatgg gagtttttaa aatcatgttt cagtggtaaa
    59941 agtaccaaac tggattctcc atagtaaaat gatatctcct gctagtgaat catctactaa
    60001 taagtccata tttcgcttgg gaacgggctt gggacttaga agccaagtat ccaactctcg
    60061 ttcaggcgat atgaagggtt tgacttggtg ttctttataa aatttttcta aaatagtatt
    60121 cacggatagc atctttcaaa catttatttc ctattctaac aaatttctaa atactttaag
    60181 aaatttatag tctgtcaagt ttttttcttg acacatgcca gaaatctgct ataatagaac
    60241 atgtgctaaa tagctcagct atttcaccga aataaaaaat taaagaaatg agactttaaa
    60301 aatggcagtt aaaatccgtt tgactcgtat gggttctaag aaaaaacctt tctaccgtat
    60361 caacgtagca gattcacgtt caccacgtga cggacgtttc atcgaaacag ttggaactta
    60421 caacccactt gttgctgaaa accaagtaac tttgaaagaa gaccgcgttc ttgcatggtt
    60481 ggctaatgga gctcaacctt cagacacagt acgtaacatc ctttcaaaag aaggcgtatt
    60541 gaaaaaattc cacgattcta aattctcaaa ataagtttaa agtaggttga cagatggata
    60601 cgattgaaaa tctcattatt gcgattgtga aacccttaat ttcacaacca gatgccttaa
    60661 ctatcaagat tgaggataca ccagaatttt tggaatatca tttgaatctt gatcaaagcg
    60721 atgtgggtcg tgtaatcggt cgtaagggtc gcactatttc tgcgataaga acgattgtct
    60781 actctgtccc aactgaatac aaaaaagtaa gaatcgttat tgacgaaaaa taagaagggc
    60841 gggacggatg tctcgctttt ttgtgtggaa tagaagatat agtaaaatga aacaagaaca
    60901 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag taaaggtgta
    60961 ctattctagt ttcaatatac tataaaagat tgaacgttta ggcaattcca agactactta
    61021 atcgaacatt aacagcagtc tcggactgat gaaggtctct ttatgaagtt agtggaggaa
    61081 gtcggagaag tagccgaggt tttgaatagg cgctctggtc gaaaagaagg gataggattc
    61141 gaacgaggaa cttgccagag aactggctga tatcatttac tacaccgtcg caatcgtagc
    61201 tattaatcat attgacctta ccaagactgt ctttgagaaa gacaaaaccg cagccgttaa
    61261 ttaccaacat aaacataatt tggaaggatt cttgaaggga aagtagagat gttgtcccct
    61321 tcctccaact tgagaaaatc cttggaacgt gataaaataa aggataagga tttttaataa
    61381 ttcattatat agaatgagtg gatttcttta tgaagaggtt tgaagtatct acagaaattg
    61441 gtagcctctc tgttacttat caaaagcaaa agaaagtgct agtttgtcta aacggagcag
    61501 gtttgctacc aagttatgaa aatttttcac ttatacttga aaaacctcct cctacaattg
    61561 gttatttgac aattgatttt ccgaacacag gtaggagtcc gattcatgac caagctggaa
    61621 aaaaactaga taatcttgca gatgcggttt atgaagtact tgaagaatta ggaatttctg
    61681 aatatatact ttgtgcacat agttggagtg gaattttagc ttgcaaatta ctcgagaaac
    61741 caattaagcg tcagacttta gtagcaattg aaccgacaac taaaaaagtc atgtttgctg
    61801 atttttcaga aaatccttat ccagaaatgg aagagcagat gaggctgatt gacgagtgtg
    61861 gtcctgaact ttattttaag aacttaactc aagcaacatt tagtcctgaa acgaataaaa
    61921 aaatctggga attaatgcaa gaaaaaggct tagagttgga aaatcaagat ccagaatttc
    61981 agatatctgg agagattact gaggaagatt ttgagaattt gtcgatagaa tctcatgtcc
    62041 ctgtatttat tttttgtcag acttatagag aaaaagagta cagagaatca gaatattgga
    62101 cttccaatac taaactcatt ttaggaagga atcaccatta tttacaatgg tcagaatcgg
    62161 aaaaaattgc ggctattatt cgagaattgt cagaataaga tggaaaaaag gagattacag
    62221 gagacaagat gaactacttt aatgttggga aaatcgttaa tacgcaggga ttacagggtg
    62281 agatgcgagt cttgtctgtg acggattttg cagaagaacg gtttaaaaaa ggagctgagc
    62341 tggctttgtt tgatgaaaaa gatcagtttg tccaaacagt gaccatcgct agccaccgta
    62401 aacagaagaa ctttgacatt attaaattca aagatatgta ccatatcaat actatcgaaa
    62461 agtacaaggg atacagtctc aaggtcgctg aggaagattt gaatgaccta gacgatggtg
    62521 aattttacta tcacgagatt atcggtttgg aagtctatga gggtgatagc ttggttggaa
    62581 ccatcaagga aatcctgcaa ccaggtgcta atgatgtctg ggtggtcaaa cgaaaaggca
    62641 aacgtgattt gcttttacct tatatcccac cagtggttct caatgttgat attccaaata
    62701 aacgggtcga tgtggaaatc ttagaagggt tagacgatga agattgatat tttaaccctc
    62761 tttccagaga tgttttctcc actggagcac tcaatcgttg gaaaggctcg agaaaaaggg
    62821 ctcttggata tccagtatca taattttcga gaaaatgctg aaaaggcccg tcatgtagat
    62881 gatgagccct acggaggcgg tcagggcatg ttgctcagag tacaacctat tttcgattcc
    62941 tttgatgcta ttgaaaagaa aaatccgcgc gttattctcc tcgatcctgc tggaaagcag
    63001 tttgatcagg cttatgctga agatttggct caagaggaag agctaatctt tatctgtggg
    63061 cactatgagg gttatgatga gcgcattaag accttggtaa cagatgagat ttccctaggc
    63121 gactatgttc tcactggtgg agaattggca gctatgacca tgattgatgc tacagttcgc
    63181 ctgattccag aagtgattgg caaggagtct agccaccaag atgatagttt ttcttcaggt
    63241 cttttagaat atcctcagta cacacgtccc tatgattatc gaggcatggt cgtgccagat
    63301 gtattgatga gtggccacca tgaaaagatt cgtcagtggc gattgtacga gagtttaaag
    63361 aaaacctacg agcgcagacc ggatttactt gaacattatc aactgacagt agaagaagaa
    63421 aaaatgctgg cagaaatcaa agaaaacaaa gaataaagga gaaacctatg caagtaatca
    63481 aacgtaatgg cgaaattgct gaatttaatc cagataagat ttaccaagcc atcttgaagg
    63541 cagcccaaac tgtttatgtt ttgacagatg atttgcgtca aaatcttgct caagtcacta
    63601 agaaggtagt tttggattta caagaagcca aggtggaacg tgcgactatc agtatgattc
    63661 aatctatggt tgaacatcgt ttattgggcg caggttacat taccattgca gaacactaca
    63721 tttcctatcg tttacaacgt gacttggaaa gaagtggtta tggagatcat atcgcagttc
    63781 atttacattt tgaacaaatt cgctaagaaa aaagagtggg atgaagcaac tacatctcac
    63841 tctttcttaa atctattttt ttgggctgtt tggacagttg aggggacaaa tcgcaggcgt
    63901 tgaatatcgc ttatacggat aatccggctc acatttttgg caaaattttt cacgataatt
    63961 tgctggcctt gctgatcata tttgatgata tcacctgtaa agcttgtctc agacaagata
    64021 aggtgaacag cggtttgttt ctggatagcc tcttcaatag tggctgtaag ggagttggtt
    64081 tcagtctggt caggttggtc atgtccattt aaaaaatcat gtattttatc tagaacttgc
    64141 tggaatttat gtctcatatt ggcctccctt cttttatatc aatattatat aaaattttcc
    64201 taaaatctac aagattttac gaataaacta atgaaactaa aaaaggagaa gaaaatggca
    64261 gaatttacat ttgaaatcga agagcacttg ttgactcttt ctgaaaacga aaaaggttgg
    64321 accaaggaaa ttaaccgtgt gagctttaat ggtgcccctg caaagtttga tattcgtgct
    64381 tggagtccag accatactaa aatgggcaaa gggattactc tctcaaatga agaatttcaa
    64441 acgatggtgg atgcctttaa aggcaactaa tactcttcga aaatctcttc aaaccgcatc
    64501 agctttgcct tgccgtatgt atggttactg acttcgtcag tttcatccac aacctcaaaa
    64561 cagtgttttg agcagcctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
    64621 aagttttcaa aataaaaaaa ggatattgag tcatgataac tcggtatcct tttttagtta
    64681 gtaaagtaag cctgattttt aaggcgttga agtaggggac ggctaataaa actaatagcc
    64741 agaagtttgc caaggtctgg aatgataaag ggaagaaccc ccacaacaag agctttttca
    64801 aatgccattc cagctaggaa atgcaagctg agaatcccgc cgacaaagac aagggcatca
    64861 cccaagaggt ttgcaagaaa aatcttaaca acaccactct tgctgttggt tagagaggaa
    64921 gtaagtccag agtaaacgag ataaaaccaa agatagcctg cagtagggcc aactaaagcc
    64981 tgaaaaccag ctccacctcc tgcaaagaca ggaagaccga tagcacctag aagaagatag
    65041 agtccagcag aaagtacagc ctctctcggt ctaaagacag tagcaatcaa gccgattgca
    65101 aagttttgca gagtgaaggg aacaggtcca attggaagac tgatttgtgc caaaacagca
    65161 atgagagcag ccccaatagc agggatagca taaacgtgag cttttttcaa aatagttaac
    65221 ctcttttcta atgtatacta actattatac tcatatagga gtcgatgtca accatttttt
    65281 aaaaacaagg taacaaaaac tgtaacagcc gattttcgtg actagtcaag ttggataatt
    65341 tttttgttga ttcgaaaatc attaaaaaag aagcagacat attt
//
LOCUS       DBEROT010000007        55346 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.07, whole genome shotgun sequence.
ACCESSION   DBEROT010000007 DBEROT010000000
VERSION     DBEROT010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 55346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.07"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            547..1386
                     /gene="licT"
                     /locus_tag="ACL8CG_000531"
     CDS             547..1386
                     /gene="licT"
                     /locus_tag="ACL8CG_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGS1343183.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1404..3242
                     /locus_tag="ACL8CG_000532"
     CDS             1404..3242
                     /locus_tag="ACL8CG_000532"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGS1343184.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     MKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3255..4670
                     /locus_tag="ACL8CG_000533"
     CDS             3255..4670
                     /locus_tag="ACL8CG_000533"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS1343185.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIELLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5262..6308
                     /gene="pheS"
                     /locus_tag="ACL8CG_000534"
     CDS             5262..6308
                     /gene="pheS"
                     /locus_tag="ACL8CG_000534"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGS1343186.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHHHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6308..6817
                     /locus_tag="ACL8CG_000535"
     CDS             6308..6817
                     /locus_tag="ACL8CG_000535"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343187.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6894..9299
                     /gene="pheT"
                     /locus_tag="ACL8CG_000536"
     CDS             6894..9299
                     /gene="pheT"
                     /locus_tag="ACL8CG_000536"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGS1343188.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIEFSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVSLLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9472..10473)
                     /locus_tag="ACL8CG_000537"
     CDS             complement(9472..10473)
                     /locus_tag="ACL8CG_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS1343189.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10629..11032
                     /locus_tag="ACL8CG_000538"
                     /pseudo
     CDS             10629..11032
                     /locus_tag="ACL8CG_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            11158..11424
                     /locus_tag="ACL8CG_000539"
     CDS             11158..11424
                     /locus_tag="ACL8CG_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1343190.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            11685..13934
                     /gene="metE"
                     /locus_tag="ACL8CG_000540"
     CDS             11685..13934
                     /gene="metE"
                     /locus_tag="ACL8CG_000540"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGS1343191.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVSAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLTVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEVILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            13998..14864
                     /gene="metF"
                     /locus_tag="ACL8CG_000541"
     CDS             13998..14864
                     /gene="metF"
                     /locus_tag="ACL8CG_000541"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGS1343192.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15551..17764
                     /gene="pnp"
                     /locus_tag="ACL8CG_000542"
     CDS             15551..17764
                     /gene="pnp"
                     /locus_tag="ACL8CG_000542"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGS1343193.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17780..18397
                     /gene="cysE"
                     /locus_tag="ACL8CG_000543"
     CDS             17780..18397
                     /gene="cysE"
                     /locus_tag="ACL8CG_000543"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGS1343194.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18409..19293
                     /locus_tag="ACL8CG_000544"
     CDS             18409..19293
                     /locus_tag="ACL8CG_000544"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343195.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYQLAKLSNLEVLLADSSY
                     QEQISQLKFQAFSGEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19380..20723
                     /gene="cysS"
                     /locus_tag="ACL8CG_000545"
     CDS             19380..20723
                     /gene="cysS"
                     /locus_tag="ACL8CG_000545"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGS1343196.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20716..21102
                     /locus_tag="ACL8CG_000546"
     CDS             20716..21102
                     /locus_tag="ACL8CG_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGS1343197.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            21106..21990
                     /locus_tag="ACL8CG_000547"
     CDS             21106..21990
                     /locus_tag="ACL8CG_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1343198.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            22127..22726
                     /locus_tag="ACL8CG_000548"
     CDS             22127..22726
                     /locus_tag="ACL8CG_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343199.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNTK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            22869..23039
                     /locus_tag="ACL8CG_000549"
                     /pseudo
     CDS             22869..23039
                     /locus_tag="ACL8CG_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            23395..24672
                     /locus_tag="ACL8CG_000550"
     CDS             23395..24672
                     /locus_tag="ACL8CG_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1343200.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            24685..25332
                     /gene="vex2"
                     /locus_tag="ACL8CG_000551"
     CDS             24685..25332
                     /gene="vex2"
                     /locus_tag="ACL8CG_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGS1343201.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            25384..26763
                     /gene="vex3"
                     /locus_tag="ACL8CG_000552"
     CDS             25384..26763
                     /gene="vex3"
                     /locus_tag="ACL8CG_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGS1343202.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            26943..27026
                     /gene="pep27"
                     /locus_tag="ACL8CG_000553"
     CDS             26943..27026
                     /gene="pep27"
                     /locus_tag="ACL8CG_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGS1343203.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            27075..27731
                     /gene="vncR"
                     /locus_tag="ACL8CG_000554"
     CDS             27075..27731
                     /gene="vncR"
                     /locus_tag="ACL8CG_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGS1343204.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            27728..29056
                     /gene="vncS"
                     /locus_tag="ACL8CG_000555"
     CDS             27728..29056
                     /gene="vncS"
                     /locus_tag="ACL8CG_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGS1343205.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVAQD"
     gene            29197..30078
                     /locus_tag="ACL8CG_000556"
     CDS             29197..30078
                     /locus_tag="ACL8CG_000556"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGS1343206.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(30399..31589)
                     /locus_tag="ACL8CG_000557"
     CDS             complement(30399..31589)
                     /locus_tag="ACL8CG_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGS1343207.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FAGIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(31827..32183)
                     /locus_tag="ACL8CG_000558"
                     /pseudo
     CDS             complement(31827..32183)
                     /locus_tag="ACL8CG_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc.;
                     incomplete; partial in the middle of a contig; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
     gene            complement(32196..32960)
                     /locus_tag="ACL8CG_000559"
     CDS             complement(32196..32960)
                     /locus_tag="ACL8CG_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS1343208.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSTLSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDTLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            complement(33000..33758)
                     /locus_tag="ACL8CG_000560"
     CDS             complement(33000..33758)
                     /locus_tag="ACL8CG_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1343209.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LSPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEARAQQFLSKIINHESDKVK"
     gene            34034..36256
                     /gene="recJ"
                     /locus_tag="ACL8CG_000561"
     CDS             34034..36256
                     /gene="recJ"
                     /locus_tag="ACL8CG_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGS1343210.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            36431..38092
                     /locus_tag="ACL8CG_000562"
     CDS             36431..38092
                     /locus_tag="ACL8CG_000562"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS1343211.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMSYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            38161..38940
                     /locus_tag="ACL8CG_000563"
     CDS             38161..38940
                     /locus_tag="ACL8CG_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1343212.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            39052..40272
                     /gene="murM"
                     /locus_tag="ACL8CG_000564"
     CDS             39052..40272
                     /gene="murM"
                     /locus_tag="ACL8CG_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGS1343213.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMSTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            40277..41509
                     /gene="murN"
                     /locus_tag="ACL8CG_000565"
     CDS             40277..41509
                     /gene="murN"
                     /locus_tag="ACL8CG_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGS1343214.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            41588..42289
                     /locus_tag="ACL8CG_000566"
     CDS             41588..42289
                     /locus_tag="ACL8CG_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGS1343215.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            42329..44173
                     /gene="uvrC"
                     /locus_tag="ACL8CG_000567"
     CDS             42329..44173
                     /gene="uvrC"
                     /locus_tag="ACL8CG_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGS1343216.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPSI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            44163..44996
                     /locus_tag="ACL8CG_000568"
     CDS             44163..44996
                     /locus_tag="ACL8CG_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1343217.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDCVLEVLDGQYGLENPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(45178..45978)
                     /locus_tag="ACL8CG_000569"
     CDS             complement(45178..45978)
                     /locus_tag="ACL8CG_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1343218.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            46149..46754
                     /locus_tag="ACL8CG_000570"
     CDS             46149..46754
                     /locus_tag="ACL8CG_000570"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGS1343219.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            46767..48167
                     /gene="pepV"
                     /locus_tag="ACL8CG_000571"
     CDS             46767..48167
                     /gene="pepV"
                     /locus_tag="ACL8CG_000571"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGS1343220.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            48221..48799
                     /locus_tag="ACL8CG_000572"
     CDS             48221..48799
                     /locus_tag="ACL8CG_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGS1343221.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            48959..49246
                     /locus_tag="ACL8CG_000573"
                     /pseudo
     CDS             48959..49246
                     /locus_tag="ACL8CG_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            49417..50742
                     /gene="brnQ"
                     /locus_tag="ACL8CG_000574"
     CDS             49417..50742
                     /gene="brnQ"
                     /locus_tag="ACL8CG_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGS1343222.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            50840..51877
                     /locus_tag="ACL8CG_000575"
     CDS             50840..51877
                     /locus_tag="ACL8CG_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGS1343223.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDGQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KEQNIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYIKSALVD"
     gene            51879..52349
                     /locus_tag="ACL8CG_000576"
     CDS             51879..52349
                     /locus_tag="ACL8CG_000576"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS1343224.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLEKETRLRFLEEMSLIQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            52352..53068
                     /gene="ldcB"
                     /locus_tag="ACL8CG_000577"
     CDS             52352..53068
                     /gene="ldcB"
                     /locus_tag="ACL8CG_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGS1343225.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(53108..53245)
                     /locus_tag="ACL8CG_000578"
     CDS             complement(53108..53245)
                     /locus_tag="ACL8CG_000578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343226.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            53377..53802
                     /gene="rplK"
                     /locus_tag="ACL8CG_000579"
     CDS             53377..53802
                     /gene="rplK"
                     /locus_tag="ACL8CG_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGS1343227.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            54010..54699
                     /gene="rplA"
                     /locus_tag="ACL8CG_000580"
     CDS             54010..54699
                     /gene="rplA"
                     /locus_tag="ACL8CG_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGS1343228.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            55077..55214
                     /locus_tag="ACL8CG_000581"
                     /pseudo
     CDS             55077..55214
                     /locus_tag="ACL8CG_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        16865 a        10183 c        12418 g        15880 t
ORIGIN      
        1 tttcataata aaacacccca aaagttagat tttttctgtc taacttttgg ggtgtagttc
       61 acagttgaag agccagaaaa ttaaagtgtc ttttactcaa tcaaaaatag taacgcctat
      121 tcttttggtg aataagacta ttgtttggta tggtgcaatg ccattattag ggaaggtaga
      181 tgagatgacc atattacgtt tggaatcagc tagtatagct tctgaactag tggcaggttt
      241 acgatagaga aaatttttaa aaatttctat gtatgatttt catttcttta gtgagactgt
      301 tgccattatc acattcgaat cacacaaaat aaaaaaattt ctacaagtac ttgacaaata
      361 gattgaaata tcataaaatg aaaatggtta cagagttatt aattatttaa gcttcatgtc
      421 accattaaaa attgaaataa aaggatgtta tcactaatac aagtgagcag gaacctattt
      481 aatcacatcg gaagaagttt cttgatgttt ttaagtaggt tccttttatt ttaaaaggga
      541 aattttatga tcataaaacg aatactaaac cacaatgccg taattgcgca aagtaaaaaa
      601 gatatcgata ttcttctttt tggaaggggc atagcttttg gaagaaaaac tggagataaa
      661 gtaaatccaa ttgatattga gaaaagtttt tttctcaaaa atagagataa tatgacccgt
      721 tttacagaga tgtttattaa cgttcctttg gagttggtgt acatcaccga aaaaataatt
      781 aacctaggta aaataacatt gggtaataat tttgatgaaa ttatctatat taatttaacg
      841 gatcatattt cttcgagcat agaacgttat aaagaaggga ttattatttc gaatccccta
      901 cgctgggaaa tatcgaaata ttataaagaa gaatttgaac ttgggaaaag ggctttacaa
      961 ataataaaaa aagagttagg tattgaactt ccaattgacg aagctgcatt catagcgcta
     1021 cattttgtta atgctaattt agaaaataat tttcaagagt cgtataaaat cactgaaata
     1081 attatgggaa ttgagaaaat cattcaagat ttctattgta ctgagtttaa ccaagattct
     1141 attgattatt atagattcat aactcatata aaattatttg cccatcgctt ggttgaaaat
     1201 acaacttatt gtgacgatga tgatgaagac ttgttagcat taatgaaaaa taaatatcct
     1261 agagaatatg aatgtggtga acaggtggca atgtttatac aaactgagta caattatttg
     1321 ctgacttcta gtgaattagt ttatttgatg gctcatattc gtcgcttaac aaaaaattta
     1381 gattaataga ataggagaat accatgagtt ataaagataa ggtacaaaaa atcctcgatg
     1441 taattggagg tgaaaaaaat gtcaatagag ttacccattg tgtaacacgt ttaagattag
     1501 aattaaaaga tgaaaattta gtcaatgatg atgatatgaa gaagatacca ggtgtaatag
     1561 gtattatgaa aaagaatgga caatatcaaa ttatacttgg taatgatgta gctaattatt
     1621 ataaagaatt cgttaaactt ggcaattttg aatccgattc agttgttcaa gggcacaaag
     1681 ggaatatttt agaaagaatc attgagtata tcgctggttc catgactcca atcattccag
     1741 caatgttagg gggaggtatg ctgaaagtct tggtaattat tttaccaatg cttggtatat
     1801 tgcaatcaga ttctcagact attgcttttt tgacattttt tggggatgcg ccatattatt
     1861 tcttaccgct gttattagct tattctgcat cacaaaaatt aaaagtaaca tctacattag
     1921 ctatgtctgt agcaggtgta cttctccatc caaattttgt tcaaatggtg caatcaggga
     1981 atcctcttag tttatttggt gtacctgtga caccagctag ttatggttcg tcagtcgttc
     2041 caattcttat tatggtttgg ttgatgaaat atattgaaaa aatgattgct aaattaacac
     2101 cagctgttac taagagtttt ttgcaaccta cgctagtatt attagtatca agctgtattg
     2161 ccttagttgt agtcggacct attggagtaa ttgttggtga aggattatca aatctagttg
     2221 ggcaaatgta tggtgtagct ggatggctta cattagctat tcttggtgct attatgccat
     2281 ttattgttat gactggaatg cattgggctt ttgcacctat ttttttggcg gcatctattg
     2341 ctactccaga cgtattaatt cttccagcaa tgttagggtc aaacttagct caaggggctg
     2401 cttcgatggc tgttgcatta aagagtaaaa ataataatac aaaacaaatt gcttttgcag
     2461 caggtttctc agccttactt gcaggaatta ccgaacctgc attatatggt gtgactttaa
     2521 aatataaaaa accgctttat gcagctatga ttggtggtgg attagcggga ttatttgcag
     2581 gtcttactag tgttaaagcg tatctatttg ctgtcccatc tttgatagcg ttgcctcaat
     2641 ttatttattc tgatgtacca tcaaatattg taaatgcttt aattgtggcg gtcatttcgg
     2701 ttgttattac ctttgtatta gcttatatat ttggaatcga tgaagaagag agttctagta
     2761 atttagaagt taaagctgga gtttcaaata aaaaaatgat attttctcct atatcaggag
     2821 aaatcattcc gttaagcgat gtccaggata aaacattttc agataaacta attggagacg
     2881 gagtagcgat tatcccaagt gaaggtaagg tttatgcacc atttgatggg aaaattacaa
     2941 atatttttcc gactaagcac gcaattggat tgaagagtga tgagggtgtt gagttactaa
     3001 ttcatattgg attagatact gttgagctaa aaggtcaagg ttttattagt catgtagaag
     3061 aaggagacag agttttcaaa aatcagttga tttttgaaat ggacttgaat ttaatcaaga
     3121 ctaaaggcta cgaaacagtt acaccagtaa ttgtaacgaa taccaatgat tttctagatg
     3181 tattagtatt acctaataat cagacaatcg agcattctaa ggaattactg gtaatattat
     3241 aatggaggaa agttatgacc atttttccag atgattttct ttggggtgga gctgttgcag
     3301 ctaatcaagt agagggagca tataatgaag atggtaaggg cttatcagtt caggatgtgt
     3361 tacccaaagg tggattagga gaagcaacag aaaatcctac agaagataac ttaaaattga
     3421 taggtattga tttttatcat aaatataagg aagatatatc cttgttttct gaaatgggct
     3481 ttaatgtttt tcgtacttct attgcatgga gtagaatttt tccaaaagga gatgaagaag
     3541 aacctaacga agctggtttg aaatattatg atgaattgtt tgatgaacta catgctcacg
     3601 ggatagagct acttgtaact ctttcacact atgagactcc attatattta gcaagaaaat
     3661 atcatggatg ggttgatagg agaatgattc atttttatga aaaatttgct cgaacagttt
     3721 tagaaaggta taaagataaa gttaaatatt ggcttacatt taacgaagta aactctgttt
     3781 tggaattacc atttactagt ggaggaatag atatacctaa ggagaatctt tcgaaacaag
     3841 aattatatca agctatacat catgaattag tcgcctcaag tttggttaca aaaattgctc
     3901 gtgagattaa ttcagagttt aaggtggggt gtatggtatt agctatgcca gcttatccaa
     3961 tgactccaaa tccaaaagat gtatgggcga ctcatgagta tgagaatcta aattatctat
     4021 tttcagatgt gcatgttaga ggttattatc cgaattatgc aaaaagatat tttaaggaac
     4081 atgacattaa catagagttt gcagctgaag atgcagagtt attaaaaaat tataccgtag
     4141 attttttatc ctttagctat tacatgagtg tgactcaatc tgctcttcca acacagtata
     4201 attcaggaga agggaatatt attggtggtt tagtaaatcc ttatttagag tcttcagagt
     4261 ggggatggca aattgatcca attggactac gtataatttt aaatagatat tatgaccgtt
     4321 atcaaatccc attatttata gtagaaaatg gattaggtgc taaagatcaa ctaataaaag
     4381 atgaacttaa taacttaacc gtccaagatg attatagaat tcagtatatg aaagaacatt
     4441 tattgcaagt tgctgaagct ctacaggatg gtgttgaaat tatgggctat acatcttggg
     4501 gatgtattga ctgcgtttct atgtccactg cacaactttc taaaaggtac ggtctcattt
     4561 atgttgatcg aaatgatgat ggaaatggca cattcaatcg atataagaaa atgtccttta
     4621 cttggtataa aggagtgatt gaatcaaatg gagaatcctt attcaaatag tttgtttatt
     4681 gatgattaga tattatcacg gttaaggcaa catctcatta aatatgaaat aaagaggttt
     4741 ggaagacatc aaattctaaa cctctttatt ttataggggg attaattaat ttaattttgt
     4801 tacagagagc cgattataaa tagttaactt aggatagatg ggttatatat agtagactga
     4861 atctaaaata gtacgaaaca attgctaaaa catttataga aattaatttt actttcccaa
     4921 tcgatttgtt ttcatcttat ttcaatccgc tataaagtta gataagaata agctaacaag
     4981 cagaagtaag ataggtcttg caagaatggt aaaaatctga taaactaagt agtaattgaa
     5041 taggaatctg aaagactagt agcccaaggg aagtatatca gggaggagag ccgtgactgc
     5101 aagctctcta tatgaaagct gggtgaattc acttgcgcat ggatttagaa atgaaggtct
     5161 gacttgtcag atgaaaacgg atggtaccgc gtgtcaacgc tccgagtgga gtttttggca
     5221 tgtggttttc tttttatcta cgagagactg atggaggaaa tatgtcaact attgaagaac
     5281 aattaaaagc gcttcgcgaa gaaacgctgg ctagcttgaa gcagattact gctggaaatg
     5341 aaaaagagat gcaagatttg cgtgtctctg tccttggtaa aaagggttcg ctcactgaaa
     5401 tcctcaaagg gatgaaagat gtttctgctg agatgcgtcc aatcatcggg aaacacgtca
     5461 atgaagctcg tgatgtcttg actgctgctt ttgaagaaac agctaagctc ttggaagaaa
     5521 agaaagtcgc ggctcaactg gctagcgaga gtatcgatgt gacgcttcca ggtcgtccag
     5581 ttgcgactgg tcaccatcac gttttgacac aaaccagtga agaaatcgaa gatatcttca
     5641 tcggtatggg ttatcaagtc gtggatggtt ttgaagtgga gcaagactac tataactttg
     5701 aacgtatgaa ccttccaaaa gaccacccag ctcgtgatat gcaggatact ttctatatca
     5761 ctgaagaaat cttgctccgt acccacacgt ctccagttca ggcgcgtgct atggatgccc
     5821 atgatttttc taaaggtcct ttgaagatga tctcgccagg gcgtgtcttc cgtcgcgata
     5881 cggacgatgc gacccacagt caccaattcc accaaatcga aggcttggta gttgggaaaa
     5941 atatctctat ggctgatctt caaggaacgc ttcagttgat tgtccaaaaa atgtttggtg
     6001 aagagcgtca aattcgtttg cgtccatctt actttccatt cacagagcca tctgttgagg
     6061 tggatgtttc ttgcttcaaa tgtggtggag aaggctgtaa cgtatgtaag aaaacaggtt
     6121 ggatcgaaat tatgggggcc ggtatggttc acccacgtgt ccttgaaatg agtggtatcg
     6181 atgcgactgt atactctggc tttgcctttg gtcttggaca agagcgtgta gctatgctcc
     6241 gttatggaat caacgatatc cgtggattct accaaggaga tgtccgcttc tcagaacagt
     6301 ttaaataatg attagaaaag tagaaatggc agatgttgag gtgttggcta aaattgccaa
     6361 acaagccttt cgtgaaacct ttgcgtatga taatacggaa gagcagttac aggaatactt
     6421 tgaagaggct tatagtctga aaactttgtc aactgagttg ggaaatcctg actctgaaac
     6481 ctatttcatt atgcatgagg aggagatagc tggttttctc aaagtcaact ggggaagtgc
     6541 tcaaactgag agagaattag aggacgcttt tgaaattcaa cgcctctatg tgctacaaaa
     6601 attccaagga tttggactag gtaagcaact gtttgaattc gcacttgaac ttgctacaaa
     6661 aaatagtttt tcttgggctt ggctaggtgt ttgggagcat aatacaaaag ctcaagcgtt
     6721 ttataaccga tatggttttg aaaaatttag ccaacatcat tttatggttg gtcaaaaagt
     6781 agatacggat tggttactga gaaagaaatt aaggtaagaa gagaattctt ctattgaaat
     6841 gataggaaag gaaaagaacc agtgtggcaa tggtcattct ggagaactaa attatgcttg
     6901 tatcttataa atggttaaaa gaattggtgg gcattgatgt gccatcacag gagttggctg
     6961 aaaaaatgtc aaccacaggg atcgaggtcg aaggtgtcga atcaccagct gccggtcttt
     7021 caaaaattgt cgtcggtgag atcttgtcct gcgaagatgt gccagaaact caccttcatg
     7081 tttgtcaggt taacgttggc gaagaagaag agcgtcagat cgtttgtggt gccccaaatg
     7141 tgcgtgcagg catcaaggtt atggtggctc ttccgggagc tcgtatcgct gacaattaca
     7201 aaatcaaaaa aggaaaaatc cgtggcttag agtcacttgg aatgatctgt tcacttggtg
     7261 aattgggtat ttctgactca gttgtaccta agaaattcgc agatggtatt caaattttgc
     7321 cagaaaatgc cgttccaggt gaggaagtct tttcatatct agacttggat gatgaaatca
     7381 tcgaattttc tatcacacca aaccgtgcag atgccctttc tatgcgtgga gtggctcacg
     7441 aagtggcagc catatatgac aaggcagtca actttaaaga atttactttg acagaaacaa
     7501 atgaagctgc gacagatgcc ctttctgtgg gcattgagac agacaaggcg ccttactatg
     7561 cagctcgtat cttggacaat gtgactatcg caccaagtcc acaatggttg caaaaccttc
     7621 tcatgaacga aggcatccgt cccatcaata acgttgtaga cgtgacaaac tacatcctgc
     7681 tctactttgg tcaacctatg catgcttttg acttggacac atttgaaggg actgacatcc
     7741 gtgtgcgtga agcgcgtgct ggtgaaaaat tggtgacctt ggacggtgaa gaacgtgact
     7801 tggacgtgaa tgacctagtc atcactgttg cagacaagcc agtagccctt gcaggtgtca
     7861 tgggtggtca agcaacagaa atctctgaaa aatctagtca tgttgtcctt gaagctgctg
     7921 ttttcaatgg caaatctatc cgtaagacaa gtggtcgcct gaaccttcgt tctgagtcat
     7981 cttctcgctt tgaaaaagga attaatgtgg caacagttaa tgaagccctt gatgcggcag
     8041 ctagcctgat tgcggaactt gcaggtgcga cggtgcgtaa gggtatcgtt tcagcgggtg
     8101 agcttgatac ttcagatgta gaagtttctt caactcttgc tgatgttaac cgtgtcctcg
     8161 gaactgagct gtcttatgct gatgtcgaag acgtcttccg tcgtcttggc tttggtcttt
     8221 ctggaaatgc agacagcttt acagtcagcg taccacgtcg tcgttgggat atcacaatcg
     8281 aagctgatct ctttgaagaa atcgctcgta tctatggata tgaccgcttg ccaaccagcc
     8341 ttccaaaaga cgatggtaca gctggtgaat tgactgtgac acaaaaactc cgccgtcaag
     8401 ttcgtaccat tgctgaagga gcaggtttga cagaaatcat cacctatgct ctaacaactc
     8461 ctgaaaaagc agttgagttt acggctcaac caagtaacct tacggaactc atgtggccaa
     8521 tgactgtgga tcgttcagtc ctccgtcaaa atatgatttc aggtatcctt gataccgttg
     8581 cctacaacgt ggctcgtaag aataaaaact tggcccttta cgagattgga aaagtctttg
     8641 aacaaacagg taatccaaaa gaagaacttc caaatgaaat caacagtttt gcctttgcct
     8701 tgacaggctt ggttgctgaa aaagatttcc aaacagcagc agttccagtt gatttcttct
     8761 atgctaaagg aatcctagaa gcgctcttta ctcgcttggg actagaagtg acctatacag
     8821 caacagctga gattgccagc cttcacccag gacgtacagc agtcatttca ctcggtgacc
     8881 aagttcttgg ttttcttggc caagtgcatc cagtcactgc taaggcttac gatattccag
     8941 aaacgtatgt ggctgagctc aacctttcag tcatcgaagc tgcccttcaa cctgctgctc
     9001 catttgtgga aatcacgaaa ttcccagcag tcagccgtga cgtttccctt ctcctcaagg
     9061 cagcagtaac tcaccaagaa gttatagatg ctatccaagc tgccggcgtg aaacgtttga
     9121 cagatatcaa actctttgac gttttctcag gtgagaaatt gggacttggt atgaagtcaa
     9181 tggcttatag cttgaccttc caaaatccag aagacagctt aacggacgaa gaagtcgcac
     9241 gctacatgga aaaaatccaa gcatcgcttg aaaaaaaagt gaacgcagaa gtgcgttaaa
     9301 cgatagtagg atacaaattc cccctctagt ttatgaacac tagaggggtg attttatata
     9361 atactcaatg aaaatcaaaa agcaaactag gaagctagcc gtaagctgta cttgagtact
     9421 gtaaggcgag gctgacgtgg tttgaagaga ttgtcgaaga gtataaaata attaaaatgt
     9481 gatttctgta aaaatacatc tatgatcaga gttttgaaaa cttacaatgt ctaaatcttt
     9541 aacatagtag tggtttttag gcaataaaat atgatctatt gttgcattaa aaagttttgg
     9601 actttggcta ttccaagttc ctctttcaaa aggtggtagt acatttaatg cgtccctatg
     9661 agagcttatt tttgcaagtg ctccatgacg catagttgca ttaaaatcac ctgcaataat
     9721 agcctttgga tattttgaag ccaattgatt atgaatgatg tttaagtctt gcttccagat
     9781 ttccattaaa cctggcagag gaggagcagt atgcaaggca atgatatctg gtatattttg
     9841 ttttctcgaa tgtaatacaa ttgtcccgaa ccgtgttgta tgaaaagttt tagcttctgt
     9901 atagaaacca taacttttct tgacaatcac agtcacagga gctattccac tattggtagg
     9961 tggagaagtg aaaatatcat agttggccat agaaagtcca acttgatgaa acaatagttt
    10021 gattctctgg ttttcttgct cacctctgat attggtagct agttcaggga atatagccat
    10081 atcggcgtca aaatggctaa aaattcgctc aatatgttgt gcttctattt gattagcgac
    10141 gttccaagtt actaatttta aggttttagt cttatttgat gcagaagaaa gggttttatc
    10201 tgttccgaat aatagtaata tgagcgatag taagagcaaa atgccagagt aaaaccgtat
    10261 ttgtttattt ttcttgtaaa aagataggga aaaaaatacg aaacttaaaa tagcagccat
    10321 agttgcagta gctaagggga aggcataaat ctgtgccaag ataggtctgg tagatagcca
    10381 aatattaaga ttagaagatg gaaaaaaaga ataagttatg atagggataa caaagagaat
    10441 gaccgaaagg gcagagagaa atgttttaat cattgtgtga gtacctcaat ttgcaatggt
    10501 tgctcggagc taatgtgact ttgtgacttt acttgattga tattcttttt cttgtcttcc
    10561 tcatagatta agtacaaccc aagtaaaaaa agtccaattt aagattgaaa tgattaaaag
    10621 gcacagaaat gcaagacaat tatactacaa aaggcaaaca tttgacaatc gatagccgtc
    10681 gcttaatcga aagatggaaa aaagaaggga aatcaaatag agaaattgcc tctctgcttg
    10741 gaaaagttcc tcaaactatc cacactgaaa tcaagcgtgg gacagtccga caatgtcttg
    10801 gaaaagggcg cttcaaagag gtttattctg ccgactacgc tcaacagtct taagaaacta
    10861 aaggaaaaga ttctccacta tacataacca aaaattttcg cctgaaatga tggttatggt
    10921 taaaggggtt aacgtgggaa tttcaaccat ttactattgg attcatcgtg gaaaattggg
    10981 gttaagcaag caggatctgc tttatcctag aaaaggaaaa tcgcttaaga aataggctag
    11041 caccaacttt aaacccactg gtcaatctat cgaatcataa ttcgctcatt tttttaaaaa
    11101 tacatagacg taaaaaaaag agggttaagt gatgaagaat agtgctattg ggagtaattg
    11161 gaaggatgtc catctgagct ctttagcaag gaggaaatcc ttgaaagtga tatgcgagtg
    11221 gctatcatga gcgagttgat tgaggctagg tatgaacaag gaatcagtca gaaaaagctg
    11281 gaagaagtca gtggaataag ccagcctgtc atagctagga tggagacagg aaagactagt
    11341 cctcagttgg atacagtctt aaaagtccta gccagtttag gaaagacact agcagtcgtc
    11401 ccacttgaac agggaaaaag ttgactagaa tcagttatag tcttttctaa taacaggtca
    11461 tagtcactta taagaattac taataacatg ttttagtatt ctaattggaa tatagctgta
    11521 aagtaagaat tacaaaggat ttgagacgtt tgcttcaagt ctttttcttt tgtccgaaac
    11581 agatatatag tttcaaacta tatcaaaccc taatttttta caattataca gacgctttct
    11641 tttctgttaa gatagtttca acaacaaatt ttggaggaca catcatgtca actacaatca
    11701 tcggtttccc tcgtttgggc gaattccgtg aattaaaatt tacaactgaa aaatacttta
    11761 gaaaagaaat ctcagaagaa gaacttttag cagcagcaaa agacttgcgt gctaaacact
    11821 ggaacattgt caaagaaaaa ggcatcactg aaattccatc aaatgacttt tctcactatg
    11881 ataacttcct agatgcggct ttccttttca acgtggtgcc tgcatccgtt caaaacttgg
    11941 acttgtctga ccttgagcgc tacttcgctt tgggacgtgg ttaccaggga gaaaaagggg
    12001 acgttcgcgc ccttccaatg aagaaatggt tcaacactaa ctaccactac atcgttccta
    12061 aatttgaaaa agacactcaa gtaaaattgg ctggtcacaa gattttcgat gagttccaag
    12121 aagccaaaga acttggattg aacactcgtc ctgttcttgt aggtcccttc actttccttc
    12181 aattgtcaga ctttgaagaa ggcgtgaaag cagacgactt cgtagatagc ttagtgtctg
    12241 cttaccaaga agtttttgct aaattggctg aacttggtgc gactcgcatc caattggatg
    12301 aagcggctct tgtaaaagac ttgacagctg aagaaaaagc tcttttcttg aacctttaca
    12361 acaaactctt ggctgacaaa aaaggtcttg aagtcttgct tcaaacttat ttcggtgatg
    12421 ttcgtgacgt atacgctgac cttgtaaact taccagtaga tgctatcggt cttgactttg
    12481 ttgaaggtaa gaaaactctt gaactcgtta aaggtggctt cccagctgac aagactctct
    12541 atgtaggtat tgtcaatggt aaaaacatct ggcgcaacaa ctacgaaaag agcttgactg
    12601 ttcttgagca aatcccagct gaaaacatcg ttttgacaag ctcttgctca cttcttcatg
    12661 tgccatttac aactgctaat gaagaatttg aaccagcact cttgaaccac tttgcctttg
    12721 cagttgaaaa attggatgaa atccgtgact tggatgctat ccgaaatggt caaggttcag
    12781 aagctcttgc agccaacaaa gaactctttg cgactgagcg tgttggtgaa aatgctgaac
    12841 ttcgtgcgcg tatcgctggc ttgacagacg cagactacac tcgtttgcca gcctttgcag
    12901 aacgtgaagc tatccaagaa gaagctttca aacttccagc tcttccaaca acaacgattg
    12961 gttcattccc tcaaacaaaa gaagttcgtg ccaaacgttt ggcttaccgt aaaggtgaat
    13021 tgtctcaaaa agagtacgac gctttccttg ctgaaacgat tgacgaatgg atcaagtggc
    13081 aagaagatat tgactttgat gtccttgttc acggtgaatt tgagcgtaat gacatggttg
    13141 agtacttcgg tcaaaacttg tcaggatacc tcttctctaa aaatggatgg gtacaatcat
    13201 acggtatgcg tggggtaaaa ccaccaatca tctggggtga tgtcactcgt cttaacccta
    13261 tcactgttaa atggtctagc tatgcacaaa gtcgtacaaa caaacctgtt aaaggtatgt
    13321 tgactggacc tgttaccatc cttaactggt cattcccacg tgaagacatc tctatcaagg
    13381 attcaactct ccaaatcgcc cttgctatca aggatgaagt acttgacctt gaagctgctg
    13441 gtgtgaaaat catccaaatc gacgaggctg ctcttcgtga aaaattgcca ctccgccgta
    13501 gcgactggta cgaagactac cttgactggg ctattcctgc cttccgcttg gtacactcaa
    13561 cagtagcgcc agacacacaa atccacactc acatgtgtta ctcagaattt acagatatca
    13621 tcccagctat cgataacatg gatgcagacg ttatttcctt tgaagctagc cgttcaaacc
    13681 ttgaaatctt ggacgaactc aaagcgaaaa acttccaaac agaagtggga cctggggttt
    13741 acgatatcca ctcacctcgt gtaccaaatg aaggcgaaat cgacaacaca atcgaagtca
    13801 tccttgctaa agtgccaagc aagaaagttt ggatcaaccc tgactgtggt ttgaaaacac
    13861 gtggtatccc agaaacaaaa gaaagcttga tccgccttgt tgaagcagct aaagctgcgc
    13921 gtgagaaatt gtaagattgg atttctctcc atacagtggt tgttcaaaaa gaaatcaact
    13981 agaaaaggtt attacatatg tcacgccaaa caccgtcact ctcatttgaa gtgttccctc
    14041 caaacccagc cgtgggtaat gataacatta tttcagcctt gcaggatatg caggagttgg
    14101 ctccccattt tatcagtgta actgccagca ataataaatt taatatcaag gaaacgacgg
    14161 ttcgtttggc tgactttatc caaaatgatt tggcgattcc gaccattgcc cacttgccag
    14221 ctatttatct aactaaggac aaggttgctg aaactattgc tgacttggac aaagttgggg
    14281 tgcagaaaat cttggctctt cgtggggata ttattccaga cgtggaacca caaaaggatt
    14341 tccgctatgc aacagacttg attgagttta tcaaggaaca aacccctcac tttgatatta
    14401 ttggagcttg ctatccagaa gggcatccag attcgccaaa tcagatttca gatattcaaa
    14461 atcttaagaa gaaagtggat gcaggctgtt cgagcctcgt aactcagctc ttctttgaca
    14521 atgagcgctt ctatgatttt caggacaagt gcatcttggc tgggattgat gttcccattc
    14581 atgcaggaat tatgccaatt ctgaatcgaa atcaggctct ccgactcttg aagacttgtg
    14641 agaatatcca tcttccacgc aaatttaaag ccatcttaga caagtatgag catgaccctg
    14701 agtcgctcag agcagcagga cttgcctatg cagtggacca aatcgtggac ttggtaactc
    14761 aggatgttgc cggtgtgcat ctctatacga tgaataatgc tgatacagca aaatacatcc
    14821 atcaagcaac ccatgccttg tttaatcacc agtctctagg ataataaaag caaaccattc
    14881 ttctcaggtg aggggaatgg ttccttttta atggtaaaga cctcactttt taagaaaaat
    14941 atgataaaat aaattctgta cgtacttgat acaaagatga aggtattaaa taatacaatg
    15001 catttaaact gtaagattta acgacacgag tgagtcaaat cgatgttatt tgacgagaga
    15061 gttagtaaag catttaacta atcgcccgat agcgattagc gtgaaagctt tagatacttt
    15121 agtattaaac ctttctaatg atttatatct tgaaaactga actcgcctac aactctgtgg
    15181 aaaaagataa atctccctag gagcagtcgc tccgtcgttc gatttcctat tttcctttga
    15241 gttgcttgac ggcttagtat cttgagtaat tgaattttgg tctcatttct taggaaaaaa
    15301 gataagcttc ctagcactcg tcgagtgcga cgtcaccttc ctatttttct acagaaatgt
    15361 tcggcaagcc gaaccgtcca aaatatcttg tgtaattgaa cacggccgaa aagctgtgta
    15421 aaaaagataa actgtcttgt cttcatcgaa gacttcgtca gtttcctatt tttactttgc
    15481 ttttgacgtc cttggtatct tgatctttgt aggcaaggcg tataatttca tcaatccaaa
    15541 ggggattaaa atggcaaaac aagtgtttca aacgactttt gcgggtcgtg agttaattgt
    15601 agaaactggt caggttgcta agcaagcaaa tggctctgtt gtcgtacgtt acggtgagtc
    15661 aactgtcttg actgctgccg ttatgtctaa gaaaatggca actggggatt tcttcccact
    15721 ccaagtcaac tacgaagaaa aaatgtatgc ggctgggaag tttcctggtg gctttatgaa
    15781 acgtgaagga cgtccttcaa cagatgcgac cttgacagcg cgtttgattg accgtccgat
    15841 tcgtcctatg tttgcggaag gtttccgtaa tgaagtccaa gtcatcaata cagtgctttc
    15901 ttatgatgaa aatgcatctg caccaatggc tgctatgttt ggttcatctt tggcactgtc
    15961 tatttcagat attccatttg acggaccaat tgctggggta caagtgggat atgtagatgg
    16021 ccaaatcatc atcaacccaa gtcaagaaca agcagagcaa tctcttcttg aattgacagt
    16081 agctggaacc aagcacgcta tcaacatggt agagtctggt gccaaagaat tgtcagaaga
    16141 aatcatgttg gaagcgcttc ttaaagggca cgaagctgtc aaagaattga ttgccttcca
    16201 agaagaaatc gttgctgctg tcggtaaaga aaaagcagaa gtggaattgc ttcacgtgga
    16261 tgctgaattg caagctgaaa tcattgcagc ctacaacagt gacctccaaa aggcagttca
    16321 agtagaagag aaattggccc gtgaagctgc aactcaagca gtgaaagacc aagtgactgc
    16381 cgtttacgaa gaaaaatatg cgaaccacga agaatttgac cgtattatgc gtgatgtggc
    16441 tgaaatcttg gaacaaatgg aacacgcaga agtgcgacgt ttaattacag aagacaaggt
    16501 gcgtcctgat ggtcgtaagg tcgatgaaat ccgtcctttg gatgcggttg ttgacttcct
    16561 tcctcgtgta catggttcag gtctctttac tcgtgggcaa actcaagctc tttcagtctt
    16621 gaccttggct ccgatgggag aaactcaaat cattgatggt ttggatccag agtacaagaa
    16681 acgctttatg caccactata acttccctca atattctgta ggggaaacag gtcgttacgg
    16741 tgcgccaggt cgtcgtgaaa tcggtcacgg tgcccttggt gagcgtgctc ttgctcaagt
    16801 cttgccaagc ttggaagaat tcccatacgc tatccgtcta gtagcagaag ttttggaatc
    16861 aaacggttct tcatctcaag cttctatctg tgcgggaact cttgccctta tgactggtgg
    16921 tgtgccaatc aaggcgccag tagctggtat tgctatggga cttatctcag atggaaataa
    16981 ctacacagta ttgacagata tccaaggttt ggaagatcac tttggagata tggacttcaa
    17041 ggttgcaggt actcgtgatg ggattacagc ccttcaaatg gatatcaaga ttcaagggat
    17101 tactgcagaa atcttgacgg aggctcttgc tcaagccaag aaagcgcgtt ttgaaatcct
    17161 tgatgtcatt gaagcaacca ttccagaagt tcgtccagaa ttggctccaa ctgctccgaa
    17221 aattgatacg atcaagattg atgtggacaa gattaagatt gtcatcggta agggtggaga
    17281 aaccatcgac aagattatcg ctgaaacagg tgttaagatt gatatagacg aagaaggaaa
    17341 tgtgtctatc tactctagtg accaagatgc tattaaccgt gccaaagaaa ttattgctgg
    17401 tttggttcgt gaagccaaag tggatgaagt ttaccgtgct aaagtcgttc gtatcgagaa
    17461 atttggtgcc tttgttaacc tctttgataa gacagatgcc cttgttcata tctctgagat
    17521 ggcttggact cgtaccaatc gtgtagagga tttggtagaa atcggggatg aagttgatgt
    17581 taaggttatc aagattgatg aaaaaggccg tatcgatgcc tctatgaagg ctcttctacc
    17641 tcgtccgcca aaacctgagc atgatgaaaa aggtgaaaag tctgagcgcc ctcaccgccc
    17701 acgtcatcac aaggatcaca aacctaagaa agaatttaca gaaacaccaa aagattcaga
    17761 gtaagaaaag gagaaatgta tggggtggtg gcacgaaacc attgatatcg taaaagaaaa
    17821 tgatccagcg gcccgcacca ctttggaggt tttgctgact tatccaggtg tcaaggcctt
    17881 ggcggcccac cgtctctcgc attttctctg gaagtacgac ttcaaactct tagctcgtat
    17941 gcacagtcag ttttggcgct tttggactca gattgagatt catccaggag cccagattga
    18001 ttcaggtgtc tttattgacc atggttctgg tctggtgatt ggagagacag cgattgttga
    18061 aaaaggcgtt cttctctatc acggagtgac tctcggggga acagggaaag actgtggcaa
    18121 acgccatccg actgtacgaa agggagccct catatcagcc catgcccaag ttatcgggcc
    18181 tgtggaaatt ggtgaaaatg ccaaggtcgg tgctgcagca gttgtcgtag cagatgtacc
    18241 tagtgatgtg acggttgtcg gtattccggc caagattgtc cgtcttcatg gtaagaaaga
    18301 tgagcctgtt attcacgaag tcgaagaaaa acgggagtat tatgtcaata aactcgagca
    18361 ggctaaagat gccagtcaca gatcgtctgg tttgtagagg atacctatat gattcaagca
    18421 agaaacaagt taagccaaga ggagctatct gaggcgaaaa aagtaattaa ctgttgccaa
    18481 aactatgacg gtacctatcg cgatccctat ctctctaaca tgcttaattt tgacccaaac
    18541 atgcccgcct ttttccttta ttatgaaaaa ggcaaacttg ttggtttatt aactgtctat
    18601 gcagatgacc aagatgtaga agtgacgata ctggttcatc caggtcatcg ccgtcagggg
    18661 attgcgcgtg cattgtttac tagttttgag agagaaacag cttctttccc cattcggtca
    18721 gtcacttttc agacagaacg tattttttta gagaatcatc ctgactttgc cagtaactgg
    18781 ggactaatcg aggatgaaga gacagaaacc tggttaggta aggatagaag accatatcag
    18841 ttagcaaaac tttctaatct tgaagttttg ttagcagata gttcgtatca ggagcaaatt
    18901 agccagttaa aatttcaggc attttcaggg gaacatgaat cgagagaagt tgtggataga
    18961 tatgtcgctg aagctctgaa ggatccagaa agtcgcttat atattttgtt aaaagacggt
    19021 caggttattg ggacttgcac ggttgattta tcgagcgata cgaattactt ctacggttta
    19081 gcaatatcag aacctgaacg tggaaaaggc tatggaagct acttagcaaa atcccttgtc
    19141 aaccaactaa ttgagcaaaa tgataaggaa tttcagattg cagtggaaga tagcaatgta
    19201 ggtgccaaac gtttgtatga aaaaattggc tttgtcaaac agacacaggt ggtttatctg
    19261 aatgagaaag gagcaaggga ttccgaagtg tagagacatt cggactgaaa tttacttgag
    19321 ctcttagttt agtgatgaaa ctaacagttc ttggatttta gctttcttga ttatgattta
    19381 tgattaaaat ctatgacacc atgtctcgtg atttgcgaga atttgtcccg attgaggacg
    19441 gcaagatcaa gatgtatgtt tgtgggccaa ccgtgtacaa ctatattcac gtgggaaacg
    19501 cccgttcgac ggtagctttt gatacgattc gtcgctattt tgagtaccgt gggtataagg
    19561 ttgcctatat ttccaatttt acagatgtgg atgataagat tatcaaccgt gccagggaag
    19621 aaggcatcac acctcaggag gttgcggata agtacatcgc tgcctttcgt gaggatgtga
    19681 cggccttagg cgtgaaacct gcgactcgcc atccgcgtgt agtggagttt atggcagaca
    19741 tcatccgttt tgtggaagac ttgatcgaga aaggctttgc ctatgagagt caaggggatg
    19801 tctatttccg tgtagaaaaa tcccacaact atgctaaatt ggctaataaa accttggaag
    19861 atttggagct aggtgcttca ggtcgtaccg atgaagaaac ggctcgtaag gaaaatcctg
    19921 tagattttgc tctatggaaa tcttccaaac caggtgagat ttcttgggat agtccttggg
    19981 gacctggacg tccgggttgg catattgagt gttcagtcat gtcgacagag attttaggtg
    20041 ataccattga tatccacggt ggtggagctg acctagagtt tccacaccac accaatgaaa
    20101 ttgcccaatc tgaagctaaa acaggcaagg cttttgctaa ctactggatg cacaatggct
    20161 ttgtcaatat cgacaatgtc aaaatgtcta agtccttggg taacttcatt acggtacacg
    20221 atgcccttaa aactcttgat gggcaagtac ttcgtttctt ctttgcgacc cagcactacc
    20281 gtaagcctat caacttcacg gaaaaggcag ttcgcgatgc cgagaccaat ctcaagtatc
    20341 tgaagaatac ttacgaacaa ccatttacag gaaacgtgga tgcccaagag ttacaaaact
    20401 ttaaagataa gtttgtagca gctatggatg aagattttaa tgctgccaac ggtatcacag
    20461 ttgtctttga aatggccaaa tggatcaact cagggaacta tgatgcaagt gtcaagcaag
    20521 ctcttgcaga tatgttagaa atttttggaa ttgtctttgt tgaggaagtt ttggatgcag
    20581 agattgaaga cttgattcaa aaacgccaag aggcgcgtgc caatcgagac tttgagacag
    20641 cagaccaaat ccgtgaccaa ttggttactc aaggaattaa gctccttgat accaaggatg
    20701 gagtgaggtg gacacgtgat tgatgtcaat ctcattaacg ggattgcgct agcctttgag
    20761 ggggatgcgg tgtattctat gtatattcgc cgtcacctca tcctcaaagg tatgaccaaa
    20821 cccaataaac tccatcaaga agcaaccaag tatgtgtcag ccaaggctca ggctcgcctg
    20881 attgctctca tgttggagga gcaggtccta acggaaaaag aagaagaaat ctacaaacgt
    20941 ggccgcaata ccaatagcca cacaaaggct aaaaatgcag atgtcgtgac ttatcgtatg
    21001 tccacgggat ttgaagcggt tatgggctat ctccatatga ctgagaatct ggaacgtctt
    21061 gagagtttgg tttcatggtg catccaaaaa gtggagggct agaacatgag ggaaaaagaa
    21121 ctacaagact ggtttcctga ggctcggatt tcagaccaac cagtagagaa agagggctat
    21181 ctcacgctcc ctttagcttc tcagcagtgg attttgctgg aggaagctgg gctcagcgag
    21241 cgtgaaaagc agttggttgc ccttttgacc cagcaggagc aggctcgttc gctaaaccct
    21301 tggtattcct atctggttga aggcaaggga caggcaccgc aagtttttaa aaagattcag
    21361 ttggtttatt gccatctttc ttattttcag caggaaaatc tggcttcttg gctagatatg
    21421 atgcggactc tttttccgaa ttgtcagaca gtgctacagg tcggatctca ggattatgtt
    21481 ttcgtgcttc aacaagacaa atacacttct gtaagagata ttttaagtga tacgattgaa
    21541 gcggttgagt atgactttgg acttcgtctt tctatcatgt tgggtcaggt ttggtctcag
    21601 acaggacatc aagccctatc agacttaatc aaagctgagc gggatttgtt caagacatgg
    21661 tggcgtcagg gtcaccaagg tgttcatact ttttctcagc tctatctttg gagtatggga
    21721 gaaagactcg tggacttgaa gccaattaaa gaatgtctac accagatgat tttggatcaa
    21781 gatcagattc aggaaatcat tctctctctt tgggaaaata gtgctgttct cactaaaaca
    21841 gcccagcaac tctatctgca ccgcaattct ctccaataca agattgataa atgggaagag
    21901 ttgacagggc ttcagttgaa agagttgacc gacctgacct tgtgttatca attgatttta
    21961 ggttctttgt caactatagt tggtttgtaa agaagttaat atttggagaa gaggatggcc
    22021 atcttctcca tttttatgtg cagagttata gtggattgat gctgggaaag tacactgtga
    22081 ctgctaaaac attcctagaa gttgctttga tttccctaat ctatttatgc aaattttatg
    22141 ttattttact ataacagttg ttgctaagcc aaataatagt ggggaagttc atttagacgt
    22201 aagcattgaa gataatcagg gaggtagtgg gcataatttc agttctgttt caagtagctc
    22261 acaaacagct aaatatgaag aaactggtta taataacaat ttatcattat atataacgat
    22321 tgataaaacg tctgatgcaa cagctctttt gaaattaaag ttgaataatg ttgataatca
    22381 acctgctact gaagttccta gttcaggaat tactgtaaaa ttaaatacta aagataatgc
    22441 tggaaactgg acaagtgctt cgaataaaaa agaaataaca gtaaaaattg tttctgctaa
    22501 accgacatat ccagacaaaa tcttagtgaa aaatcctgat aatataaaag atacagaaaa
    22561 aaatgccatt attgaaaaat tgaaagaggc aaataaaaat catccagcag gagctccaac
    22621 ctttgctaaa ggtgaaggag agcatgcaaa tgatattgta gcaacttatt cagatggtac
    22681 aacttattat gtaccgttaa atgatgtgac aaaatatgcg aggtagtggc tgtaccactc
    22741 acttattcac ctcctcgtga tttgtagtag tgataggctt tctcactatt attataaaac
    22801 aaaataaaga tcacaacact ttttcattct gtgttgtgcc ttgagtgaaa cgaaaggaat
    22861 gaattataaa tatgaaaagt atagtcacta gcatagatga gcgcttgcgt actcgcctac
    22921 gagtgattat ctggaagcaa tggaagaaga aatcgagacg attatgggga ttgcttaagt
    22981 taggggttcc taaatggata gcagataagg tatctggctg gggcgaccac tatcaattat
    23041 attaaaatga aataagaata ggacgaatcg atcagggaag tcaaatcgat ttctaacaat
    23101 gttttagaag aagagatgta ctattctagt ttcaatctac tatagtagct cagaagtcgg
    23161 tacttaaacg tgctatatca aaaccagtcc ttgaaaaacg tgaacaggtt tcgtgtttgg
    23221 attattacct tgaacgacat gcgttaaaag ttagttgaac cgccgtatgc cgaacggcac
    23281 gtacggtggt gtgagagggg cgagagatta tcccctactc gatatttttt ttcgtatttc
    23341 ataaacattt catatttggg ttttataata gtcttacaaa tatggaggtg acaaatgaat
    23401 ccaatccaaa gatcttgggc ttatgtcagc agaaagcgac tgagaagttt tattttattt
    23461 ctgattttat tggtcttatt ggccggaatt tcagcctgtt tgactctgat gaagtccaac
    23521 aaaacagtag aaagcaatct ttataaatca ctcaatacat ctttttctat taagaagata
    23581 gagaatggtc agacattcaa gttgtcagac ctagcatctg taagcaagat taaggggctg
    23641 gaaaatgtct ctcctgaact tgagacggtc gcaaaactaa aagacaagga agcagtgact
    23701 ggcgagcaga gcgtggagcg tgatgattta tcagctgcag acaataactt ggttagctta
    23761 acggctcttg aggattcatc caaggatgta acctttacca gttcggcttt caatctaaaa
    23821 gaagggcgac accttcaaaa aggggattcc aagaaaatcc ttatccacga agaattggct
    23881 aagaagaacg gtctttcact tcatgacaag attggcttgg atgctggtca gtctgaatct
    23941 ggaaaaggac aaacagtaga gtttgagatt attggcatct tttctggtaa aaaacaagag
    24001 aaattcacag gcttgtcttc tgacttcagt gaaaatcaag tctttacaga ctatgaaagt
    24061 agccaaaccc ttttgggcaa tagtgaagct caagtcagtg cagcacgctt ctatgtagaa
    24121 aatcctaagg aaatggacgg actcatgaag caggtagaaa acttggcctt ggaaaatcaa
    24181 ggctaccaag tcgaaaagga aaacaaggct tttgaacaaa tcaaagactc agttgcaact
    24241 ttccaaacct tcctgaccat cttcctttat gggatgttga tagcaggagc tggagcctta
    24301 attctggttt tgtctctctg gttgagagaa cgggtctatg aagtggggat tttacttgca
    24361 cttggaaaag gcaagagctc gatcttccta caattctgtt tagaggtagt tttggtatct
    24421 cttggagctt tgcttccagc atttgttgca ggaaacggaa tcacaactta cctactccaa
    24481 actctactag caagtggaga tcaggcaagc ttacaagata cactagccaa agcaagcagt
    24541 ttatcaacta gtatcttatc ttttgcagaa tcctatgttt ttctagttct gcttagttgc
    24601 ttatctgtag ccctttgttt cctattctta tttagaaaat caccgaaaga aattttatca
    24661 tctattagtt aagaaggaga aatcatgact ttattacaat tacaagatgt tacctaccgt
    24721 tataagaata ctgctgaagc agtcctatat cagatcaatt ataattttga acccggaaaa
    24781 ttttacagta ttattgggga gtcaggagca ggaaaatcca cactcttgtc cctacttgct
    24841 ggtctagata gtcctgttga aggttctatc ctttttcaag gagaggatat tcgtaagaag
    24901 ggctattctt accatcgcat gcaccatatt tccctggtct ttcaaaatta taacttgata
    24961 gattatcttt ctccgctgga aaatatccga ttggtcaaca aaaaggcaag caagaataca
    25021 cttcttgagc ttggtttgga tgaaagccag atcaagcgga atgttctcca gttatcaggt
    25081 ggtcaacagc aacgtgttgc cattgctcgc agtttggtct cagaagctcc agttattcta
    25141 gctgatgagc caacaggaaa tctggatcct aaaactgctg gagatattgt cgaactactc
    25201 aaatcacttg cccagaaaac aggtaaatgt gtgattgtcg taactcacag taaagaagtg
    25261 gcacaagcgt cagatattac acttgaatta aaggataaga aactgactga aacgcgcaat
    25321 actagtaaat aatttgagct tattttgata gaatgattaa aacaaaatct agaaagggaa
    25381 tctatgttac acaacgcatt tgcctatgtt acaaggaagt ttttcaaatc gattgtcatc
    25441 ttcctgatta ttctcctcat ggcgagcttg agtttggtcg gcttgtcaat caagggagct
    25501 actgccaagg cttctcagga gacctttaaa aatatcacca atagcttctc catgcaaatc
    25561 aatcgtcgcg tcaaccaagg aacgcctcgc ggtgctggga atatcaaggg tgaagacatc
    25621 aaaaaaatca ccgaaaacaa ggccattgag tcttatgtca aacgtatcaa cgctatcgga
    25681 gatttgactg gatatgacct gattgaaacg ccagaaacca agaagaatct cactgctgat
    25741 cgtgccaaac gttttggaag tagcttgatg attacaggtg tcaatgactc ctctaaagaa
    25801 gacaagtttg tctctggttc ttataaacta gtcgaaggag agcacttaac caacgacgac
    25861 aaggataaaa tcctcttgca caaggacttg gcagccaaac acggctggaa agtaggggac
    25921 aaggttaaac tggactctaa tatctacgat gcagataatg aaaaaggagc caaggaaaca
    25981 gttgaagtga caatcaaggg actctttgat ggtcataata agtcagcagt aacctactca
    26041 caagaacttt acgaaaacac agctattaca gacattcaca ctgctgcaaa actttatgga
    26101 tacacagaag acacagccat ttatggggac gcaaccttct ttgtaacagc agacaagaac
    26161 ttggatgatg ttatgaaaga gttgaatggc atcagtggta tcaactggaa gagctacaca
    26221 ctcgtcaaga gctcctctaa ctacccagct cttgagcaat ctatatctgg tatgtacaag
    26281 atggccaacc tcctcttctg gggtagcttg agcttctcag ttctcctcct tgccctcttg
    26341 ctcagccttt ggatcaacgc ccgtcgcaag gaagtgggaa ttctcctctc tatcggcctc
    26401 aagcaggcaa gtatcttggg tcaattcatc accgaatcta tcttgattgc tatccctgct
    26461 ctagtttctg cttacttcct agctaattac actgcccgtg caattggaaa cactgtcctt
    26521 gccaatgtga cttcaggtgt tgccaaacag gctagtaagg cggctcaagc ctctaacctt
    26581 ggtggtggtg cagaagtaga tggctttagc aagaccttgt cgagcctaga catttctatt
    26641 cagacatcag actttatcat catttttgtc cttgccttgg ttctagtggt tctcgttatg
    26701 gcgcttgctt caagcaatct ccttagaaaa caaccaaaag agctcttgct ggatggtgaa
    26761 taaatttgaa aaaatgagtc tggaataaag attgcatctt gtgtttctat tcaagaatag
    26821 tggataggaa tggctattta acaattcaaa ataaatccga aagcagtggt gaaaatcatt
    26881 gctttcagtt gttttctttg tactttattg cttaaatata atatactaaa gctatggaat
    26941 ttatgagaaa ggaatttcac aacgttttat ctagtgatca gttacttaca gacaaaaggc
    27001 cagcaagaga ctataataga aaatagagta ggtatttatt ctaagaaaaa taaaaaatag
    27061 agagcagtta aagtatgaaa attttaattg tagaagatga agagatgatc cgtgaggggg
    27121 tcagtgatta tttgacggat tgtggctatg aaactattga ggcagcggac ggtcaggaag
    27181 ctctggagca attttctagc tatgaggtgg ccctggtttt actggatatc cagatgccca
    27241 agcttaacgg cttagaagtt ctagctgaga ttcgtaaaac cagtcaggtt cctgtcttga
    27301 tgttgacagc ttttcaggat gaggaataca agatgagtgc ctttgcctct ttggcagatg
    27361 gctatctgga aaaacctttc tccctctccc tcttaaaagt gagggtggac gcgattttca
    27421 agcgctacta cgatacagga cgaatctttt cttacaagga taccaaggtg gactttgaaa
    27481 gctacagtgc aagcctcgca ggtcaagaag tgcctatcaa tgccaaagag ttggaaattc
    27541 tggactatct agtgaaaaat gaaggccggg ccttgactcg gtctcagatt atcgatgccg
    27601 tctggaaagc gacagatgag gttccctttg accgtgttat tgatgtttat atcaaggaat
    27661 tgcggaaaaa gctagacttg gattgtatcc tcactgtgcg caatgttggt tataaattgg
    27721 agcgaaaatg aaacgaacag gtttatttgc aaagatattt atctatacct tctcgatatt
    27781 tagtgttctg gttatctgcc ttcatttagc tatttatttt ctttttcctt cgacttatct
    27841 gagtcatcgt caggaaacca ttggtcaaaa ggcaacagcc attgcccagt ccctagaagg
    27901 gaaagatagg cagagtatcg agcaagtgtt agatttgtat tcccagacta gtgatatcaa
    27961 ggggaccgtc aaaggtgaga tgaccgagga caagttagaa gtcaaggaca gtcttcctct
    28021 ggacacagac cgccagacaa cctctctctt tattgaggag cgcgaggtga aaacgcaaga
    28081 cggtggtact atgattctcc agtttctagc ttccatggat ttacaaaagg aagcggagca
    28141 aatcagtctc cagtttcttc cctatacctt gctggcctcc tttctgattt ccctcttggt
    28201 ggcctacatc tacgctcgga ctattgttgc accgattttg gaaatcaagc gggtgacccg
    28261 tcggatgatg gacctggatt cccaagtgcg attgcgcgtg gattctaagg atgagatagg
    28321 taatctcaag gaacaaatca atagcctcta ccagcatctc ttgactgtta ttgcggactt
    28381 gcatgaaaag aatgaagcca ttctccagct ggagaagatg aaggtcgaat tcctacgagg
    28441 agcttctcat gaattgaaaa caccgctggc tagtttgaaa atcctaatcg aaaatatgag
    28501 agagaatatc ggtcgttata aggatagaga ccagtatctg ggagttgcct tggggattgt
    28561 ggatgaactc aatcaccatg ttctgcagat actttccctc tcttctgtgc aggaattgcg
    28621 agatgatagg gaaacaattg acctcctcca gatgacgcaa aatctggtca aagattatgc
    28681 cttgctagcc aaggaaagag agctccagat agacaatagt ttgacccatc agcaggctta
    28741 tctaaaccca tcagttatga agttgattct ttctaatctc atcagcaatg ccattaagca
    28801 ctctgttcca ggtggcttag ttcgaattgg agaaagagaa ggagaacttt ttatcgaaaa
    28861 tagctgtagc tcagaggaac aagaaaaact agcccagtct ttttctgaca atgctagtcg
    28921 caaggtcaag gggtctggta tggggctctt tgtggttaag agtctattag aacatgaaaa
    28981 attagcttat cgtttcgaga tggaggagaa tcgtttaacc ttctttatag attttccaaa
    29041 agtcgcccaa gactagggag agaaagggtt tacatagatg gagttagaag aaaatcaatc
    29101 gaaactgcgg gaaaaactag atttttttgg caaaaagtga taaaatgaac aatgtaaatg
    29161 ggatgaccca taaaaatata caggaggcct gataaaatgg caatcgtttc agcagaaaaa
    29221 tttgtccaag cagcccgtga caacggttat gcagttggtg gatttaacac aaacaacctt
    29281 gagtggactc aagctatctt gcgcgcagca gaagctaaaa aagctccagt tttgatccaa
    29341 acttcaatgg gtgctgctaa atacatgggt ggttacaaag ttgctcgcaa cttgatcgct
    29401 aaccttgttg aatcaatggg tatcactgta ccagtagcta tccaccttga ccacggtcac
    29461 tacgaagatg cacttgagtg tatcgaagtt ggttatactt caatcatgtt tgacggttca
    29521 caccttccag ttgaagaaaa tcttaaattg gctaaagaag ttgttgaaaa agcacacgct
    29581 aaaggtatct cagtagaagc tgaagttggt actatcggtg gtgaagaaga cggaatcatc
    29641 ggtaaaggtg aattggctcc aatcgaagac gctaaagcaa tggttgaaac tggtatcgac
    29701 ttcttggcag ctggtatcgg taacatccac ggtccttacc cagtaaactg ggaaggtctt
    29761 gaccttgacc acttgcaaaa attgacagaa gctcttccag gattcccaat cgtattgcac
    29821 ggtggatcag gtattcctga tgagcaaatc caagcagcta tcaaacttgg tgttgccaaa
    29881 gttaacgtta acacagaatg ccaaatcgca ttcgctaacg caactcgtaa atttgctcgt
    29941 gactacgaag caaacgaagc agaatacgac aagaaaaaac tcttcgaccc acgtaaattc
    30001 ttggctgacg gtgtaaaagc tatccaagca tcggttgaag aacgtatcga cgtattcggt
    30061 tcagaaggta aagcataatc tagctgaata atacagataa aacctgcctg tgagggtggg
    30121 ttttttgatt tcaagctact cgttttagta tagtaaactg aatctagact agcacaatgc
    30181 tgcttctata gcgttttgaa actagaatag gataacataa ctgctaaaag atttctataa
    30241 attcatttga ttttcctaat caatttgttc gtatcctatt tcactccact ataaaatatt
    30301 cttatcaatt gatttgaatg ccaaaattcc atcgttccgg tcttatttca tttggctata
    30361 aaaaactctc ctgggaaatt ccaggagagt atgattactt atttgaactt gaatccttcg
    30421 taaataagct ccgtttttgg attttgtttc ttaatctgtt tggcaagtgc cttcatcata
    30481 gaaataggac cacacatata gacggttgca tgttcgggca cttctttttg ttcaaaatta
    30541 agatagccgt cttttgtact gtcgattaga tggagttcaa aattaggatt tttctgagca
    30601 tagtcacgga gtaaatcaag gtagactgca ttttcttctc cacggaagct atagtagaag
    30661 tgaacccgtt tatctaaaat aggatgttca cggatgtaag agatgaaggg ggtgatccca
    30721 atacctccag caatccaaac ctgattttct cgtccttctt ctatgatcat gtgtccgtaa
    30781 gctctgtcta gggttacttt gctgccggct tgaagattat catagatatt cttggtatgg
    30841 tcgcctgaat ttttaacagt aaagtaaaga gtttgaccat gacctcctga gatagaaaag
    30901 ggatgtggag cactttcaaa gccttcttgg aaaatcttta gaaaggcaaa ttgtcctgat
    30961 tgatagttga aaggtctgct aagatggatt tgaatttctc tagtatcgtg atttaagcgt
    31021 ttgagatggg taattttccc tagatagggg aaggaaatct tttgatatag aaaaatgata
    31081 taaaaaccag ctagtaagcc taaaagggca tagctaccaa caagaaaact tagaagatta
    31141 aatgtaagga gacgattgcc cattatcatg tagatgtgaa agagtcctaa aatataggct
    31201 aggtaaacca ggcggtgaat ccatcgccaa gcttcgtatt ggatgtattt gcctaaatag
    31261 gcgacaagga tgatgccggc aaagatatag atggcaagat taccaaactg agcagctaag
    31321 cgagagcccc acaaaccgcc catactaaag ttatgaaaga ttagtaggat gatggagaga
    31381 aaggctgtga atttgtggac ggtgtagacc ttctccaaac cgtgaaacca gctttctagt
    31441 agtgggagac gagtggctag gataaaagtc agagataggc ttgttaaagc tagtcctgga
    31501 atcatgaatt ggggagaagt gttcatccaa gtcaaaagag tcaagataaa actagctatg
    31561 ataaagagta gtcctttgac tgatttcata gaaaattcca tttcatttag atttcgattt
    31621 gttgtaaatg aatttgttac attttatcat agaaaatgta tggtgtcaaa ttgaggtcta
    31681 taaatatcta ctatcatcaa aaaactctcc aatgaactag agagctaatt tgttattctg
    31741 cagcttgttg ccaacgtttt gctagcatat gagacaggtt agaaattgct aggttaaagc
    31801 tgaagtagat gagggcaatc aggatgtaaa gactgaatcc ctgaacgaat aacctcagcg
    31861 atataagcgc cgtgatagag tcccacgcag agaacagctg tccaataaat cggaatcatg
    31921 atagtatggt cactgataag aggtaggcca taaaaaacaa taacaaactg caccaagagg
    31981 ggagtgtttt ggtaaaattc cacaaagatg cgagctaaaa tgcgtaaaat tggacgttta
    32041 ctggttgaca tggcaccaaa gaagactcct aagaccatgg cgaggataaa ggatccaatc
    32101 gctagggcaa gagtaaagag gaaaccattg aaaaattgtc caaaatcctg aaaataggct
    32161 gtccaagatg ataaatctgt catagggtat cctccttaat ctgcggtatg actagatggt
    32221 ttgagcttgt aacggtcata aagtttctgc aaactaccat ccttgctcca tttagtgacc
    32281 aaggtatcaa gatagtcgtt gagctctgta tttgatttct tggtaacaat accgtagtca
    32341 gatggcttga aactatcatc tagtagtgct gtccgtttac tagtgtagcc agatagagta
    32401 gagcggtcaa cggaaaaggt atcgatacga tgagcgtgca gggaagtaat caattctggg
    32461 taggaaccaa gttcgacgaa tttaaacttc agacctttct ttttacccag ttcagtaatc
    32521 aggcgttggg tgatagaacc ttgggcgact ccgatggttt tgccgtttag gtcctcaatc
    32581 tttttgattt tggcagattt attgaccaaa aatccagaag cgtctgtgta gtagggactg
    32641 gtaaagttgt agagtttttt gcgttcgtcc gtgatggtaa aggtcgcgat atccatatcg
    32701 acctgttcat tgtctagaag ggggccgcgg gtttgtgctg taaccggcac atagcgaatc
    32761 ttgaccttga gttcatcagc taccatcttg gccaagtcgg tttcgatacc agaataagta
    32821 ccggtcttgg gatctttgta accaaaattg ggaacgtctt gtttgacacc gacaaccagt
    32881 tcgcctcttt tttgaatgtc tgcgatacta gtatcagcct ggactggttt ggcagcagca
    32941 aggccgaaaa ggctaatcaa taatgctgat aaaaagaatt ttttttcata ggcgcctcct
    33001 tatttgactt tgtcactttc gtggttgata attttgctga ggaattgttg ggcacgagct
    33061 tcgcttggat tgtcaaaaaa gttatcgaca tctgtcgtat ctactaaaac ttctccgtcg
    33121 gccataaaga taatgcggtc cgcaacctct cgagcaaagc ccatttcgtg ggtaacgatg
    33181 atcatgttca tcccatcatg cgccagtttc tgcataactg ctagaacatc tccgatagtc
    33241 tcaggatcaa gagcagatgt tggttcatca aagaggagga gttccggatg catagcaaga
    33301 ccacgagcga tggcgatccg ctgtttttgt ccaccagata gcatggcggg ataggaatct
    33361 ttcttgtccc acatatttac aaattccaga tatttttggg cggttttttc agcttctttt
    33421 ttatcaattc ctagaacttt aatgggcgaa agtgtcacat tttctaacac cgttttgtgt
    33481 ggataaaggt taaaatgttg aaaaaccatg ccgacttcct tgcgaagagg taccaaatct
    33541 ttctggctgg caccagcaac ttggtgccca ttgactagga gacttccttt gtcaacagcc
    33601 tctaaaccat tgatcgtacg gataagagtg gacttcccag agccagaagg tccaagcagg
    33661 acaacaactt gtcctttttc aaaacggaga ttgatgttgc ggagtgcgtg gtagtctccg
    33721 taatattttt cgacgttttt aaattctact aaagccatga gagatctcct ttatgttagg
    33781 ttttataaca cgattctaca ataaaagaat gttcttgtca aaccatatct gaaaaattca
    33841 ctatagtgaa ataagaacag gaaaaatcga tcgggacagt caaatcgatt tctaacaata
    33901 ttttagaagt agaggtgtac tattctagtt tcaatatact ataaaatgtt ataaaaaagc
    33961 aatctggata gagaaaacgt ctaaatcatg ttataatgaa gcaatagaat tcttagaaag
    34021 agtggatgtc tttttgataa cacctactta tgaatggcag tttgccctgc aggtagaaga
    34081 tgcggatttt acaaagatag ccaagaaggc tggactgggt cctgaggtgg ctcggttatt
    34141 gtttgagaga gggattcagg accaagaaag tctgaagaag tttttagaac cttccttgga
    34201 ggacttacat gatgcttatc tgctccatga tatggacaag gcagtggagc ggattcgtca
    34261 ggctattgaa gaaggggaaa atattctcgt ttatggagac tatgatgcgg atggcatgac
    34321 ttcggcttct attgtgaagg aaagtttgga acaacttggt gcggagtgcc gagtttacct
    34381 gccaaatcgt tttaccgatg gctatggccc taatgctagt gtttataaat actttatcga
    34441 gcaagaagga atttccttga ttgtgacggt ggacaatggg gttgctggtc atgaggctat
    34501 tgcattggct cagtctatgg gagtagatgt cattgtgaca gaccatcatt ccatgcctga
    34561 aaccctgcca gatgcttatg ctattgtcca tcctgaacat ccagatgcgg attatccttt
    34621 taaatatttg gctggttgtg gagttgcttt caagttggct tgtgccctgt tagaagaagt
    34681 gcaagtggaa ttgcttgatt tggtcgctat tggaactatt gcagatatgg tgagtctgac
    34741 ggatgaaaat cgtatcttag ttcaatatgg tctggaaatg ttgggtcata cccagcgcat
    34801 tggtctgcaa gaaatgctgg acatggctgg gattgctgct aacgaagtaa cagaagaaac
    34861 ggttggtttc cagattgctc ctcgtttgaa tgccttgggc cgcttggatg atcccaatcc
    34921 tgccattgat ttgttgactg gatttgatga tgaggaagcg catgagattg cccttatgat
    34981 tcaccagaaa aacgaagagc gcaaggaaat cgttcagtct atctatgaag aagccaagac
    35041 catggtggat cctgagaaga aggttcaggt cttggccaag gaaggctgga atcctggggt
    35101 tctaggaatc gtggctggtc gtttattgga agaattggga cagacagtca ttgttcttaa
    35161 tatagaagac ggtcgtgcca agggcagtgc tcgtagtgtg gaagcggtcg atatttttga
    35221 agctctggat ccctatcgag acctcttcat cgcctttgga ggtcatgcag gtgcagcggg
    35281 tatgacgctg gaagttgagc aactctcaga tttatctcag gttttggaag attatgttcg
    35341 tgaaaaaggt gcagatgctg gtggcaagaa taagttaaac ctagatgaag agttggattt
    35401 ggaggcactt agcttggaaa cggtcaaaag ttttgaacgt ttagctcctt ttggaatgga
    35461 taatcagaaa cctatttttt atatcaagaa ttttcaggtc gaaagtgctc gtactatggg
    35521 ggcaggtaat gcccatctaa agctgaaaat ttccaagggt gaggcgagtt ttgaagtggt
    35581 agcctttggt caaggcagat gggcgacaga gttttctcaa accaagaatc tagagttagc
    35641 ggttaaattg tctgtcaacc aatggaatgg ccaaactgcc ctccagttga tgatggtgga
    35701 tgcgcgagtg gaaggtgttc aactttttaa cattcgtgga aaaaatgcag tcttgccaga
    35761 aggtgttcca gtcttggatt ttcctggaga actgccaaat cttgcggcta gtgaagctgt
    35821 tgtcgtaaaa aacattccag aggatattac tcagctgaag accatttttc aggaacagca
    35881 tttctctgct gtctatttca aaaatgatat tgacaaggct tattatctga caggttatgg
    35941 gactagagat cagtttgcca aattgtacaa gactatttac cagttcccag agtttgatat
    36001 tcgctacaag ctgaaagatt tggctgcata tcttaatatt caacaaatct tgctggtcaa
    36061 gatgattcaa gtatttgaag aactaggctt tgtgacgata aaagatggtg tgatgacagt
    36121 caataaagag gcgccaaagc gggagatagg agaaagtcaa atttaccaaa atctcaaaca
    36181 aaccgttaaa gaccaagaaa tgatggcgct gggtacggtg caagaaattt atgatttttt
    36241 gatggaaaaa gagtagaagt taggaaagag ttgggaaatc aactcttttt tgaaaacaga
    36301 ccttcatttt gaaaatcatc aaaaaaatgg tataatggta ggaaaagatt cggctgaaag
    36361 tatcagaact tttagaataa gagggtagaa ttgccctata atcaagataa actaagattt
    36421 tggaggaaaa atgagtaata tcagtttaac aacacttggt ggtgtgcgtg agaatggaaa
    36481 aaatatgtac attgctgaaa ttggagagtc catttttgtt ttgaatgtag ggttaaaata
    36541 tcctgaaaat gaacaattag gggtcgatgt ggtgattcca aacatggatt acctttttga
    36601 aaatagcgac cgtattgctg gggttttctt gacccacggg catgcggatg ccattggtgc
    36661 tctaccgtat ctcttggcag aggctaaagt tcctgtattt gggtctgagt tgaccattga
    36721 gttggcaaag ctctttgtca aaggaaatga tgccgttaag aaatttaatg atttccatgt
    36781 cattgatgag aatacggaga ttgattttgg tgggacagtg gtttccttct tccctacgac
    36841 ttactccgtt ccagagagtc tgggaattgt cttgaagaca tcggaaggaa gcatcgttta
    36901 tacaggtgac ttcaaatttg accaaacggc tagtgaatct tatgcaactg attttgctcg
    36961 tttggcagag attggtcgtg acggcgtcct ggctctcctc agtgattcgg ccaatgcaga
    37021 cagcaatatt caggtggcta gtgaaagtga agttagggat gaaattaccc aaactattgc
    37081 tgactgggaa ggtcgtatca tcgttgcagc tgtttccagt aatctttctc gtattcagca
    37141 gatttttgac gctgcggata aaacaggtcg acgtatcgtc ttgacaggat ttgatattga
    37201 aaatatcgtc cgcacagcga ttcgtcttaa gaagttgtct ttagccaacg aaattctttt
    37261 gattaagcct aaagatatgt ctcgctttga agaccatgag ttgattattc ttgagacagg
    37321 tcgtatgggt gagcctatca atggacttcg taagatgtcg attggtcgcc atcgttatgt
    37381 agaaatcaag gatggggacc tagtctatat tgctacggct ccgtctattg ctaaagaagc
    37441 ctttgttgcg cgtgtggaaa atatgattta tcaggcaggt ggggttgtca aattgattac
    37501 ccaaagttta catgtatcag ggcacggaaa tgtgcgtgat ttgcagctga tgatcaatct
    37561 tttgcaacct aagtacctct tccctgtcca aggggagtat cgtgagttgg atgctcacgc
    37621 taaggctgcc atggcagttg ggatgttgcc agaacgcatc ttcattccta aaaaggggac
    37681 gaccatgtct tacgagaatg gagacttcgt tccagctgga tcggtttcag caggagatat
    37741 cttgattgat gggaatgcca ttggtgatgt tggaaatgtt gttcttcgtg accgtaaggt
    37801 cttgtcagag gatggaattt tcatcgtggc tattacagtc aaccgtcgtg agaagaaaat
    37861 tgtggctagg gctcgtgttc acacgcgtgg atttgtttat ctcaagaaga gtcgcgatat
    37921 tctccgtgaa agttcagaat tgattaacca aacggtagaa gagtatcttc aaggagatga
    37981 ctttgactgg gcagatctca aaggtaaggt tcgtgacaat ctgaccaagt acctctttga
    38041 tcaaaccaag cgtcgcccag ccattttacc agtagtcatg gaagcaaaat aatcgttgaa
    38101 ataaacagag agaaagtcga gtttcggctt tttcttatag aaaaatagaa ggagaaaatc
    38161 atggcagtaa tgaaaatcga gtattactca caagtattgg atatggagtg gggggtgaat
    38221 gtcctctacc ctgatgccaa tcgagtggaa gaaccagagt gtgaagatat tcccgtcttg
    38281 taccttttgc acgggatgtc tggaaatcat aatagttggc ttaagcggac caatgtagaa
    38341 cgcttgcttc gaggaactaa tctcatcgtt gttatgccca ataccagcaa tggttggtac
    38401 accgataccc agtatggttt tgactactac acggctctag cagaggaatt gccacaggtt
    38461 ctgaaacgct tcttccctaa tatgacgagc aagcgtgaaa agacctttat cgctggtctt
    38521 tctatgggag gctacggctg cttcaaactg gctcttacga caaatcgttt ttctcatgca
    38581 gctagttttt caggtgccct cagctttcaa aacttttctc ctgaaagtca aaatctggga
    38641 agtccagcct actggagagg tgtttttgga gagattagag actggacaac tagtccctat
    38701 tctcttgaaa gtctggctaa aaaatcggat aaaaagacca aactttgggc gtggtgtggc
    38761 gaacaggatt tcttgtacga agccaataat ctcgcagtga aaaatctcaa aaaactaggt
    38821 tttgatgtga cctatagcca tagtgctgga actcacgagt ggtactactg ggaaaaacaa
    38881 ttggaagttt ttttaacaac cctaccaatt gatttcaaat tagaagagag actgacttag
    38941 tttgaacttc agcatagggg gagtagaact aaaataaaat atgttttcac tagacttttc
    39001 aaacgaaagt agtagaatag taataaaata ctggaggaaa gagagtagga aatgtaccgt
    39061 tatcaaattg gcattcccac attagaatat gatcagtttg tcaaagaaca tgaattagcc
    39121 aatgtattac aaagtagtgc ttgggaggaa gttaagtcta attggcaaca tgagaagttt
    39181 ggtgtttaca gggaagaaaa attactggcg acagctagta ttttgattag aactcttccg
    39241 ctaggctata aaatgtttta catcccaaga ggacctatat tggattatgg ggataaagaa
    39301 ctcttgaatt ttgccattca gtctattaag tcctatgctc gcagtaagag agcggttttt
    39361 gtgacttttg acccaagtat ttgcctatct caaagtttaa tcaatcagga aaagacagaa
    39421 tttcctgaaa atctggctat tattgatagt ttgcaacaaa tgggagtaag gtggtcagga
    39481 aaaacggagg aaatgggaga caccattcaa cctcgtattc aggcgaaaat atacaaggaa
    39541 aattttgaag aagataaact ttccaagtca acaaaacagg ctattcgaac agcacgaaac
    39601 aaagggcttg agattcaata tggtggactg gaactattag attcattttc ggagttgatg
    39661 aaaaaaactg agaagcgaaa agagattcat ttgaggaatg aagcctatta taaaaaattg
    39721 ttagataatt ttaaggacaa ggcctatatc accttggcca ccttggatgt ttctaaacgt
    39781 tcgcaagagt tagaagaaca gttagcgaaa aatagagcct tggaagagac ctttactgag
    39841 tcgactcgaa cttcaaaagt agaagcgcag aagaaggaaa aagaacgttt gttagaggaa
    39901 ttgaccttct tgcaggaata tatagatgta ggtcaagcga gagttccttt agcggctact
    39961 ttgagtttgg aatttggtac tacctctgtc aatatatatg ctggtatgga tgatgatttt
    40021 aaacgttaca atgcaccaat tttaacatgg tatgaaacgg ctcgctatgc ctttgagcga
    40081 ggtatggtct ggcaaaattt aggtggtgtt gaaaactctc tcaatggtgg actttatcat
    40141 tttaaggaaa aatttaatcc aacgattgaa gaatacttgg gtgaatttac aatgtccact
    40201 catcctctct atcctctgtt aagacttgct cttgatttcc gtaaaacatt aagaaaaaaa
    40261 catagaaagt aagtatatgg cactaacaac actcacgaaa gaagagtttc agacttattc
    40321 tgatcaggtt tcttctcgtt cctttatgca atctgtccag atgggggatt tgctagaaaa
    40381 aagaggggct cgaattgttt atcttgcttt gaaacaagaa ggagaaattc aagttgcagc
    40441 tctggtttat agcttgccca tgctgggtgg tctgcatatg gaactcaatt cggggccgat
    40501 ttatacccaa caagatgctc ttccagtttt ttatgcagag ttaaaagaat atgccaagca
    40561 aaatggtgta ttagagttgc ttgtaaaacc ttatgaaact tatcaaactt ttgatagcca
    40621 aggtaatcca atagatgctg agaaaaaaag tattattcaa ggtttgactg atttaggtta
    40681 tcaatttgat ggcttaacaa caggttaccc aggtggagaa ccagattggt tatactataa
    40741 agatttaact gaattaactg aaaagagttt gcttaaaagt tttagcaaaa agggtaaacc
    40801 cttggtgaaa aaggctgaaa cctttggcat tcggttgaaa aagttaaaac gtgaagaact
    40861 atcgattttt aagaatataa caaaagaaac ctctgaacgt agagaatata gtgataaaag
    40921 tttagaatat tatgagcatt tttatgatac ttttggagaa caagcggagt ttctcatagc
    40981 aagcttgaat ttttcggagt atatgagcaa attgcaaggt gaacaaagta aactagaaga
    41041 aaacttggac aagttgcgac ttgatttgag taaaaatcct cattctgaaa aaaaacaaaa
    41101 tcaactgaga gaatattcta gtcaatttga aacgtttgaa gttcgaaaag cagaagcgcg
    41161 agacttgatt gaaaaatatg gagaagaaga tattgtttta gctgggagtt tatttgttta
    41221 tatgcctcag gaaacgactt atctctttag tggttcctac actgagttta ataagttcta
    41281 tgcccctgcc ctgcttcaaa aatatgttat gttggaaagc ataaaacgtg gaatacctaa
    41341 atacaacttc ctaggcattc aagggatttt tgatggaagt gatggtgttt tgcgttttaa
    41401 acagaatttt aatggctata ttgtacgcaa agcgggtact ttccgttacc atccatcgcc
    41461 tttaaaatac aaagctatcc agttactcaa aaaaatagta ggacgttaag atgaaaaagt
    41521 cagtatttag atttctttta gcttctttta gtaaaataat tcttatttgc tagaaaggtg
    41581 gagagacatg cgctggcttt ttcgtttgat aggggctttc ttttcttttg tgtggcgttt
    41641 gttttggcgt ctggtttgga tagttgtgct cttatgtgtg cttgctttcg gacttctctg
    41701 gtatctgaac ggggattttc aaggagcgct aaagcaagca gaacggtcag taaaaattgg
    41761 tcaacaaagt attgaccaat gggagaaaac agggcaactg cctaagttaa gccagacaga
    41821 tagtcaccag cattctgaag gaaggtgggc acaggcctct gctcgtattt acctggatcc
    41881 gcagatggat tcacgctttc aagaggctta tttagaagca atccagaact ggaatcaaac
    41941 tggtgctttt aactttgaac tcgtgactga gtctagtaag gcggatatta cggctacgga
    42001 gatgaacgac ggaggcactc ctgtggcagg agaggcggaa agtcaaacta atctcttaac
    42061 agggcaattc ttgtccgtaa cggtgcggtt gaatcattat tatttgtcca atccatacta
    42121 tggctactcc tatgaacgcc ttgtccatac ggcagaacat gagttaggtc atgcgattgg
    42181 cttggaccat acagatgaga agtctgtcat gcaaccagca ggttcctttt atggtatcca
    42241 ggaagaggat gttgcaaacc tccgaaaaat atatgagact agtgagtagg gtactatctt
    42301 tccctacttt ttttgctata atggaactat gaacaacttg attaaatcaa aactagagct
    42361 cttgccgacc agccctggtt gctacattca taaggataaa aatggcacca ttatctatgt
    42421 aggaaaggct aaaaatctgc gtaatcgagt acggtcctat tttcgtggaa gtcatgatac
    42481 caagacagag gctctggtgt ctgaaattgt ggattttgaa tttattgtta cggagtctaa
    42541 tattgaggca cttctcctag aaatcaacct gatcaaggaa aacaagccca agtacaatat
    42601 catgctcaag gatgacaagt cctatccttc catcaaaatc accaatgagc gctatccacg
    42661 cttgattatc actcgtcagg tcaaaaagga cggaggtctt tattttggac cctatcccga
    42721 tgtgggggca gccaatgaaa tcaagcggtt gctggatcgg atattccctt ttcgtaagtg
    42781 taccaacccg ccctctaagg tctgttttta ttaccatatc ggtcaatgca tggcccacac
    42841 catctgtaag aaggatgaga cttatttcaa gtctatggcc caggaggttt ctgattttct
    42901 gaaagggcag gataacaaaa tcattgatga gctaaagggc aaaatggcag cggcagccca
    42961 gactatggag tttgaacgtg cggcggaata ccgtgacctg attcaggcta ttggaacgct
    43021 tcgaaccaag caacgggtca tggctaagga tctccaaaat cgcgatgtct ttggctacta
    43081 tgtggataag ggctggatgt gtgtgcaggt tttctttgtc cgtcagggta agctcatcga
    43141 gcgcgatgtc aatctcttcc cctacttcaa tgatccagat gaggattttt tgacctatgt
    43201 aggacaattc tatcaagaaa aatctcacct agttcccaat gaggtactga ttccgcagga
    43261 tattgacgaa gaagctgtca aggctttggt ggataccaag attctcaaac cccaacgtgg
    43321 agagaaaaaa cagctggtca atctagccat aaaaaatgca cgtgttagtc tggagcagaa
    43381 atttaacctg ctagagaaat ctgtcgagaa gacccaagga gctattgaaa atctaggacg
    43441 tttgctccaa atcccgaccc cagtacgtat cgagtccttc gataactcta atatcatggg
    43501 aactagccct gtttcggcta tggtggtctt tgtcaacggt aaaccgagta agaaggatta
    43561 ccgcaagtac aagataaaaa cggttgttgg accagacgac tatgccagca tgagagaggt
    43621 cattcgcaga cgctatggtc gagtacagcg tgaggctttg actcctccag atttgattgt
    43681 gattgatggg gggcaaggtc aagtcaatat cgctaagcag gttatccaag aggaactggg
    43741 cttggatatt ccaattgctg ggctgcaaaa gaatgataag caccaaaccc atgaactgct
    43801 ctttggagat ccgcttgagg tggtggactt gtctcgcaat tctcaggaat ttttcctcct
    43861 ccaacgcatc caagatgagg tgcaccgctt tgccattacc ttccaccgcc aactgcgctc
    43921 caaaaattct ttctcatctc aattggatgg gattgatggt ctgggaccta aacgcaagca
    43981 aaatctcatg aggcacttca agtctctgac caaaatcaag gaagccagtg tggatgagat
    44041 tgtcgaagtt ggagtaccaa gagcagtagc agaggctgtg caaagaaagt tgaacccgca
    44101 gggagaagcc ttgcctcaag tagcagaaga aagagtagat taccaaacgg aaggaaacca
    44161 caatgaacca taaaatcgca attttatcag atgttcatgg caatgcgacg gcgctagaag
    44221 cagtgattgc agatgctaaa aatcaagggg ccagtgaata ttggcttctg ggagatattt
    44281 ttcttcctgg tccaggcgca aatgacttag tcgccctgct aaaggacctt cctatcacag
    44341 ccagtgttcg aggcaattgg gatgattgtg tcctggaggt cttggatggg caatacggtt
    44401 tggaaaatcc gcaagaaatc cagctcatgc gaatgactca gtttttgatg gagcgaatgg
    44461 atcctgcaac gactgtctgg ctacgaagct tgcctttgct ggaaaagaaa gaaattgctg
    44521 gactgcgctt ttctatctct cataatttgc caaataagaa ctatggtggt gacttgctag
    44581 ttgagaatga tacagagaaa tttgaccaac tgctagatgc ggaaacggac gtggcagttt
    44641 atggtcatgt tcacaagcag ttgcttcgtt atggaagtca agggcaacaa atcatcaatc
    44701 cagggtcgat tggcatgccc tattttaatt gggaggcgtt aaaaaatcac cgtgcccagt
    44761 atgccgtgat agaagttgaa gatggggaat tggtcaatat ccaatttcgt aaagttgctt
    44821 atgattacga ggctgagtta gaattggcca agtccaaggg gcttcccttt attgaaatgt
    44881 atgaagaact gcgtcgtgac gataactatc aggggcacaa tctggaactt ttagccagct
    44941 taatagaaaa gcatgggtat gtagaggatg tgaagaattt ttttgatttt ttgtaagagt
    45001 ttcctaaaat agccaatgca aactaaaaaa gcgattggct ggtccaatcg cttttagtat
    45061 atcttatact caatgaaaat caaagagcaa actaggaagc tagccgtagg ttgctcaaag
    45121 cacagctttg aggttgcaga taaagctgac gtggtttgaa gagattttcg aagagtgtta
    45181 ttgtaactga gattgatctg ggaggtaaga accacctaga taggtattgc tgagtttttc
    45241 aagggttccg tcttgataga gttctttgag cgctttatca aattgctctt taaactcttt
    45301 ttggtcgctt gagaaaatga tataattgct ggggctatct gcagaaggta aatcaacgac
    45361 tgagaggtct aaaccacggt ccttgataat cttttgaacg gataccttgt caaaaactag
    45421 gaaatcaaac tctccgttag caaggtctag gattcgttta ccaatatcct caccagaaaa
    45481 attaattgta gcgggattat cagtgtgttt ctgattccag ttattgatga attgagcgtt
    45541 agaagttccg gtatcctctt gtgttgtttt accagcgatc tggtcaagag aagtcaaagg
    45601 atttttcttg ttgctgacaa ggacgagggg attgttggaa atcggaagcg agtaaaggta
    45661 tttttcagca cgctcttttg tgtaactcaa attattggcc gcagcctgat agtgaccaga
    45721 atcaagtcct gggaagatac tttcccaggc ggttctttga aattgaatct cgtagtcgct
    45781 gagtttttca tctactgcct ttagaacttc gatatcgaag cctgtcagat tgcctttatc
    45841 ttcgtagtca aatggtggca cgtcgccagc tgtagcaagg acgattgtct tttgagcgct
    45901 agtctctttg ggtgtagctt gattcccaca ggcaaccaaa aatggtagga tagctagtaa
    45961 taggctaaat tttttcatac tgtctccatt caaatgtaaa gtacttgcta gtttatcaga
    46021 aactttcctg ataaaccaat atatatcttt tatgtctgtg atagaaaaac ttaatcatga
    46081 aaaatccctg caagctcttt caaattatgg tagaatggaa gcagtagaat tagaaaagga
    46141 aatcgattat gaaatttctt gaattaaata aaaaacgtca tgcgaccaag catttcactg
    46201 ataagcctgt tgatccaaaa gatgtgcgta cggctatcga aattgcaacc ttggcgccaa
    46261 gcgcccacaa cagccagcct tggaaatttg tagttgttcg tgagaaaaat gctgaactgg
    46321 caaagttggc ttatggttca aactttgagc aggtatcatc agcacctgta accattgccc
    46381 tatttacaga tacagacctt gccaaacgcg ctcgtaagat tgcccgagtt ggtggtgcta
    46441 acaatttctc agaagaacaa cttcaatact tcatgaaaaa tttgccagct gaatttgcac
    46501 gctacaatga acaacaagtc agcgactacc tagcactcaa tgcaggtttg gttgctatga
    46561 acttggttct cgctcttaca gaccaaggaa ttggttccaa tattatcctt ggttttgaca
    46621 aatcaaaagt caatgaggtt ttggaaattg aagaccgttt ccgcccagaa ctcttgatca
    46681 cagtgggtta cacagacgac aaattggaac caagctaccg cttgccagta gatgaaatca
    46741 tcgaaaaaag ataggaagaa gaaaaaatga tagcaattga ttttacagca gaagtagaaa
    46801 aacgcaaaga agacctcttg gctgacttgt ttagcctttt ggaaatcaac tcagaacgtg
    46861 atgatagcaa ggctgatgcc caacatccat ttggacctgg tccagtaaaa gccttggaaa
    46921 aattccttga aatcgcagac cgtgatggtt atccaactaa gaatgtcgat aactacgcag
    46981 gacattttga gtttggtgat ggagaagaag ttctcggaat ctttgcccat atggacgtgg
    47041 ttccagctgg tagcggttgg gatacagatc cttacacacc aactatcaaa gatggtcgcc
    47101 tttatgcgcg cggggcttcg gacgataagg gtcctacaac agcttgttac tatggtttga
    47161 aaatcatcaa agaattgggt cttccaactt ctaagaaagt tcgcttcatc gttggaacag
    47221 acgaagaatc aggctgggca gacatggact actactttga gcacgtagga cttgccaaac
    47281 cagatttcgg tttctcacca gatgctgaat ttccaatcat caatggtgaa aaaggaaata
    47341 tcacggaata cctccacttt gcaggagaaa atacaggtgc tgcccgtctt cacagcttta
    47401 caggtggttt acgtgaaaat atggtaccag aatcagcaac agcagtcgtt tcaggtgatt
    47461 tggctgactt gcaagctaaa ctagatgcct ttgttgcaga acacaaactt agaggagaac
    47521 tccaagaaga agctggcaaa tacaaggtga cgatcattgg taaatcagcc cacggtgcta
    47581 tgcctgcttc aggtgtcaat ggcgcaactt accttgccct cttcctcagc cagtttggct
    47641 ttgctggtcc agccaaagac taccttgaca tcgcaggtaa aattctcttg aacgatcatg
    47701 agggtgaaaa tctcaagatt gctcatgtgg atgaaaagat gggtgctctt tctatgaatg
    47761 ccggagtctt ccgcttcgat gaaacaagtg ctgataatac cattgccctt aacatccgct
    47821 atccaaaagg aacaagtcca gaacaaatca aatcaatcct agaaaacttg ccagttgctt
    47881 ctgtcagtct atcagaacat ggtcataccc ctcactatgt gccaatggaa gatccacttg
    47941 tgcaaacctt gttgaatgtc tatgaaaaac aaacaggcct acaaggtcat gaacaagtca
    48001 tcggtggtgg aacctttggt cgcttgttag agcgcggagt tgcctatggt gctatgttcc
    48061 cagactcaat tgataccatg caccaagcca atgaatttat tgccttggac gatctcttcc
    48121 gagcagcagc aatttatgcc gaagctattt acgaattgat caaataaaac gatagaagtc
    48181 tgagatctta tgcttggact tctttttgga gggaaagtag atgtctcaaa tcgaaagaat
    48241 caaacaggct atcatggcgg attcgcagaa tgccagctat acagagcgtg gcattgagcc
    48301 tctctttgca gcgccaaaaa ctgctcgcat caatatcatc ggtcaggctc cgggacttaa
    48361 aactcaagaa gcaggccttt actggaaaga taaaagtggt gaccgcttgc gggactggct
    48421 aggtgtggat gaagatacct tttacaattc aggttatttt gctgttttgc ctatggattt
    48481 ctactttcca ggacatggca agtcgggtga tcttccgcct cgtacaggtt ttgcagaaaa
    48541 atggcatccg cagctcttac aggaattgcc tgatattcag ttaaccctct tgattgggca
    48601 atatgcccaa gcctactatt tacaggagaa aatcagtggg aaggtaacgg agagggtgaa
    48661 acactataaa gactatctgc cagcctattt tccgctagtt cacccatcac cacgaaatca
    48721 aatctggatg gccaaaaatc cttggtttga ggcagaagta gtgccagatt tgaaaaaaag
    48781 aattaaaacc attttatagt caatgaaaat caaagagcaa actaggaagc tagtcgtagg
    48841 ctgctcaaag tacagctttg aagttgcaga taaaactgac gaagtcggta acatacgcac
    48901 ggtaaggcga cgctgacgtg gtttgaagag attttcgaag agtattagaa gaaaaagaat
    48961 gaaagaaata gcctttgacg cattttacca gctttaccaa aacgaccagc tttctttagt
    49021 ggatgtgaga gaagtggatg agtttgcagc tcttcattta gaaggtgccc acaacctacc
    49081 gcttagtcaa ttggctgata gttatgatta attggacaaa gatcgcttgc attatattat
    49141 ttgcaaatct ggaatgagat cggcgcgtgc ttgccaattc ctattagaac aaggttataa
    49201 tgttatcaat gtccagggtg gcatgttagc ctttgaagaa ctttaaaatt ttgcatttct
    49261 cctacttggt gtggactggg taggagagtt ttatttttag ataattctta tttttaagaa
    49321 aattgaaaac atttaatatt tgcctcgtga tgcttttttc agactcctaa tcgtggtata
    49381 ctaggtcagt attttataaa tatgaaggag atttttatgg ctaaaaaagg taccctaaca
    49441 ggtttgctcc tgtttggaat attttttggt gcggggaact tgatttttcc gccttctcta
    49501 ggtgctctat ctggagaaca ttttcttcct gccatcgcag gttttgtctt ttcaggcgtt
    49561 ggtatcgccg tcttgaccct tattattgga acgctaaatc ctaaaggata tatctacgag
    49621 atttcaacga agatagcgcc ttggtttgcg actctttacc tctcagttct ttacttgtca
    49681 atcggtccat tctttgctac cccacgtact gctacaacag cttacgaagt agggattagc
    49741 ccccttttgt cggatgcaaa taaaggactt ggcttgattg tatttacggt tctgtatttt
    49801 gcggcagcct atttgatttc gcttaatcca tcaaaaatct tagaccgcat tggacgtatt
    49861 ttaacgccag tctttgcaat tttgattgtt atcttggtcg ttctgggagc tatcaaatat
    49921 ggtggaacaa gtcctcaagc tgcttcagct gcttatcaag cttctgcctt tggtacaggt
    49981 ttcctagaag gttacaatac cttggacgcc cttgcctcag tggcctttag cgtaatcgca
    50041 gttcaaacct tgaaacaact tggattttca agtaagaaag aatacatttc aactatttgg
    50101 gttgttggta tcgttgttgc ccttgccttc agcgctcttt acatcggttt aggttttctt
    50161 ggaaatcatt tcccagtacc agctgaagcg atgaagggtg gaacaccagg tgtttacatc
    50221 ttgtcacaag ccactcaaga aatctttggc tcaacagctc aactcttcct tgcagctatg
    50281 gttaccgtaa cctgcttcac aacgactgtt ggtttgattg tgtcaacagc tgagttcttt
    50341 aatgagcgct tcccacaaat cagctacaag gtttatgcga cagcctttac cttgattgga
    50401 tttgctattg ccaatttggg tcttgatgcg attatcaagt actcaattcc agtactggtt
    50461 atcttgtacc caatcacgat tgctatcgtt atgattgtca ttgtcaacaa atttgttgcc
    50521 ctttcaaaac caggtatgca gttgacaatt gctgtggtta cagttattgc cattgcaagc
    50581 gtactaggaa gctcgtttaa ggttgagttt cttgcaaatc ttgttagcgt tcttcctttt
    50641 gccaaggcat ctctcccatg gttggtgcca gccattgttg gaatcttgct ctcattggtt
    50701 ctaccaaaca agcaagaaag cgatgttttt gaaatggaat aatcacttag atcacttttg
    50761 tagccaagtc tacaggagtg attttctttt tttatccgat gataaatgtg ttataatagg
    50821 tagcgaaaga ggtgaagaaa tgaatcaaac agtagaatat atcaaagaac tgacagccat
    50881 cgcatcgcca acgggcttca ctcgtgaaat ttcgaattat ttagtcaaga ctctagaagg
    50941 ttttggttac cagccagttc gcacagccaa gggtggtgtc aatgtgacca tcaaaggtca
    51001 aaatgatgag caacatcgct atgtgactgc ccatgtggac acgctgggtg ctattgttcg
    51061 tgctgtcaaa ccagatggtc gtcttaaatt ggaccgtatc ggtggttttc cttggaacat
    51121 gattgaaggt gaaaactgta ccgttcatgt ggctagcaca ggtcaaaagg tatcaggaac
    51181 catcctcatc caccaaactt cttgccatgt ctacaaggat gcaggaactg cagaacgcac
    51241 gcaggacaat atggaagtgc gtttggatgt aaaagtaagc aatgaaaaag aaactcgtgc
    51301 tcttgggatt gaggtcggtg attttatcag cttcgatcca cgaactgttg tgactgatac
    51361 aggttttatc aagtctcgtc atttggatga taaggtcagc gcagcgattt tgctcaacct
    51421 gcttcgtatt tataagaaag agaagattga attgccagta acaactcatt ttgctttttc
    51481 agtttttgaa gaagtaggac atggtgctaa ttctaacatt cctgctcagg tagtcgaata
    51541 tctggctgtt gatatgggag ctatgggcga tggccagcaa acagatgagt acacagtgtc
    51601 tatctgtgtc aaggatgcct caggccctta tcactatgac ttccgtcaac acttggtgac
    51661 cttggcgaaa gagcaaaata ttccttttaa gctggacatc tatccatttt atggttcgga
    51721 tgcttcagcg gccatgtccg caggggcaga ggtcaaacac gccctccttg gcgcgggtat
    51781 cgagtctagt cattcttatg agcgtactca tattgactcg gtggtcgcaa cagagcgtat
    51841 ggttgatgct tacattaaga gcgcgttggt agactaatat gtgtcttata tgccagagaa
    51901 ttgagctcat caagaaggga gaaaatccct attttgtcaa agagttggaa acaggctatc
    51961 ttgtgattgg agatcaccag tattttgcag gctatagtct ctttctagcc aaggaacacg
    52021 tcacggaatt gcaccattta gaaaaggaaa caagactacg ttttctcgaa gaaatgagtc
    52081 taatccaaga ggcagttgct aaggccttta ctgctgagaa aatgaatatt gaacttttag
    52141 gaaatggcga tgcccatctt cattggcatc tgtttccacg acggacaggt gatatgaatg
    52201 gtcacggtct caagggacgt ggtccagttt ggtgggttcc ttttgaagaa atgacagcag
    52261 aaacctgcca agcaaaaccg gatgagatca aaagattagt caaacgttta tcatcagaag
    52321 tagataaact attagaaata aaggagtaga aatgaagaaa agataccttg tcgtgacagc
    52381 cttgctagcc ttgagtctag cagcttgttc acaagaaaaa gcaaaaaatg aagatggcac
    52441 agctaagaca gaacagacag ccaaagctga tgggacagtc ggcagtaagt ctcaaggggc
    52501 tgcccagaaa aaagcagaag tggtcaataa aggtgattac tacagcatcc aaggaaaata
    52561 cgacgaaatc atcgtagcca ataaacatta tcctttgtcg aaagactata atcccgggga
    52621 aaatccaaca gccaaggctg agttggtcaa actcatcaaa gcgatgcaag aggcaggttt
    52681 ccctattagt gatcattaca gtggttttag aagttatgaa actcagacca agctctatca
    52741 agattatgtc aaccaagatg gaaaggcagc agctgaccgt tactctgccc gtcctggcta
    52801 tagcgaacac cagacaggct tggcctttga tgtgattggg actgatggtg atttggtgac
    52861 agaagaaaaa gcagcccaat ggctcttgga ccatgcagct gattatggct ttgttgtccg
    52921 ttatctcaaa ggcaaggaaa aggaaacagg ctatatggct gaggaatggc acctgcgtta
    52981 tgtaggaaaa gaagctaaag aaattgctgc aagcggtctc agtttggaag aatactatgg
    53041 ctttgaaggc ggagactacg tcgattaata ctcttcgaaa atctcttcag accacgtcag
    53101 cgtcgcctta cctactgact gcgtcggttc tattcacaac ctcaaaacag tgttttgagc
    53161 tgacttcgtc agttttatct gcaacctcaa agctgtattt tgagcagcct gcggctagct
    53221 tcctagtttg ctctttgatt ttcattgagt ataaaaaata aacttttctc ttgcaattcc
    53281 agataaatag tgtataatgg ataggtatgt gaaaaacata cttgtgggag gtaaaaatct
    53341 ctaattaccg ccaaaaccac aaaggaggat ttaaaaatgg ctaaaaaagt cgaaaaactt
    53401 gtaaaattgc aaatccctgc tggtaaagct acaccagctc caccggttgg acctgctctt
    53461 ggtcaagctg gtatcaacat catgggattc acaaaagagt tcaacgctcg tacagctgac
    53521 caagctggta tgatcattcc agttgttatc tcagtttacg aagataaatc atttactttc
    53581 gttacgaaaa caccaccagc tgctgttctt ttgaaaaaag ctgcaggtgt tgaaaaagga
    53641 tcaggtacac ctaataaaac taaagttgct acagttactc gtgcacaagt acaagaaatt
    53701 gcagaaacta agatgccaga tttgaacgca gcaaacgtag agtctgcaat gcgtatgatc
    53761 gaaggtactg ctcgttctat gggattcact gttgttgact aatcaataac acagtagaaa
    53821 atctcacagc agtctattag ttgcttttca tactaggcaa gtgactgagg cttgtacttg
    53881 ggtacagcaa gggagcttaa ggccgtagga agagaaaaat agtagactga aaacccgcaa
    53941 gacttcatca tttcgagaag tgacgtggga gatgaaaatc gattgaacca cttacaagga
    54001 gaatagaaaa tggctaaaaa aagcaaacaa cttcgtgctg ctcttgagaa aatcgacagc
    54061 acaaaagcat acagtgtaga agaagctgta gcacttgcaa aagaaactaa ctttgcaaaa
    54121 tttgatgcaa ctgtagaagt tgcttacaac ttgaacatcg acgttaaaaa agctgaccaa
    54181 caaatccgtg gagcaatggt attgccaaac ggtactggta aaacttcacg tgttcttgtt
    54241 ttcgcacgtg gtgcaaaagc tgaagaagca aaagctgctg gtgcagactt tgttggtgaa
    54301 gatgaccttg ttgctaaaat caacgacggt tggttggact tcgacgtagt tatcgctaca
    54361 cctgatatga tggctcttgt tggacgtctt ggacgtgtcc ttggaccacg taacttgatg
    54421 ccaaacccta aaactggtac tgtaacaatg gatgttgcta aagcagttga agagtctaaa
    54481 ggtggtaaaa tcacttaccg tgctgaccgt gcaggtaacg ttcaagcaat catcggtaaa
    54541 gtatcatttg aagctgaaaa attggttgaa aactttaaag ctttcaacga aacaatccaa
    54601 aaagcaaaac cagctacagc taaaggaact tacgtaacaa acttgactat cacaactact
    54661 caaggtgttg gtatcaaagt tgacgtaaac tcactttaat cagtagttaa agtaatgtaa
    54721 aaaagttgaa gacgctatgt ctcaactttt tttgatgtac gacgggcatg ttgtatagta
    54781 gattgaaact agaatagtac acatctactt ctaaaacatt gttagaaatt gatttgactg
    54841 tcctgatcga ttcgtcctat tcttatttca ttttattata tatttgaggt gtaagtcctc
    54901 ggtgggcacc tgctaccggt gaacccaata gcgattccca agtctgacta tcgtgaggta
    54961 gcggattaaa acggtctggg gatagaccgt tttaagtctg acgctggaaa taagaatcgt
    55021 cagaggaagg gatagcgaaa tcgtggctct acgaacagga acgtgataat aaggcctata
    55081 tagcggataa ggtatctggc tggggcgacc actatcaatt agtagctcag aagtcggtac
    55141 ttaaacgtgc tatatcaaaa ccagtccttg aaaaacgtgg actggtttcg tgtttggatt
    55201 attaccttga atgacatgcg ttaacagtta gttgaaccgc cgtatgccga acggcacgta
    55261 cggtggtgtg agaggggcta gagattatcc cctactcgat ttcgaaatct agtggaatga
    55321 atctggaata gtccatcgag ctttct
//
LOCUS       DBEROT010000008        55084 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.08, whole genome shotgun sequence.
ACCESSION   DBEROT010000008 DBEROT010000000
VERSION     DBEROT010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 55084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.08"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..228)
                     /gene="tnpB"
                     /locus_tag="ACL8CG_000582"
     CDS             complement(<1..228)
                     /gene="tnpB"
                     /locus_tag="ACL8CG_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS1343229.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGR"
     gene            complement(209..394)
                     /locus_tag="ACL8CG_000583"
     CDS             complement(209..394)
                     /locus_tag="ACL8CG_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343230.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(698..2260)
                     /gene="guaA"
                     /locus_tag="ACL8CG_000584"
     CDS             complement(698..2260)
                     /gene="guaA"
                     /locus_tag="ACL8CG_000584"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGS1343231.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2402..3100
                     /locus_tag="ACL8CG_000585"
     CDS             2402..3100
                     /locus_tag="ACL8CG_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1343232.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3143..4039)
                     /locus_tag="ACL8CG_000586"
     CDS             complement(3143..4039)
                     /locus_tag="ACL8CG_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1343233.1"
                     /translation="MSNSLKGTLLTVVAGIAWGVSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4048..4983)
                     /locus_tag="ACL8CG_000587"
     CDS             complement(4048..4983)
                     /locus_tag="ACL8CG_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGS1343234.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4980..5705)
                     /locus_tag="ACL8CG_000588"
     CDS             complement(4980..5705)
                     /locus_tag="ACL8CG_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGS1343235.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5789..6424)
                     /locus_tag="ACL8CG_000589"
     CDS             complement(5789..6424)
                     /locus_tag="ACL8CG_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGS1343236.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(6426..7253)
                     /locus_tag="ACL8CG_000590"
     CDS             complement(6426..7253)
                     /locus_tag="ACL8CG_000590"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1343237.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7275..7610)
                     /locus_tag="ACL8CG_000591"
     CDS             complement(7275..7610)
                     /locus_tag="ACL8CG_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGS1343238.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7611..8201)
                     /locus_tag="ACL8CG_000592"
     CDS             complement(7611..8201)
                     /locus_tag="ACL8CG_000592"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGS1343239.1"
                     /translation="MGDFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNH
                     ILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNG
                     IEQYISQEDYNRYLSYLNEDKIKVEIERAEKEADITIIMLQMGVEYRLEPTEEQKALY
                     HKMIDLGADIIFGGHPHVVEPSETVEKDGDKKLIIY"
     gene            complement(8217..8339)
                     /locus_tag="ACL8CG_000593"
     CDS             complement(8217..8339)
                     /locus_tag="ACL8CG_000593"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343240.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQGD"
     gene            8852..9463
                     /gene="def"
                     /locus_tag="ACL8CG_000594"
     CDS             8852..9463
                     /gene="def"
                     /locus_tag="ACL8CG_000594"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS1343241.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9508..10236
                     /gene="rlmB"
                     /locus_tag="ACL8CG_000595"
     CDS             9508..10236
                     /gene="rlmB"
                     /locus_tag="ACL8CG_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGS1343242.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10275..11186)
                     /gene="trxB"
                     /locus_tag="ACL8CG_000596"
     CDS             complement(10275..11186)
                     /gene="trxB"
                     /locus_tag="ACL8CG_000596"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGS1343243.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLIVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11252..11476)
                     /locus_tag="ACL8CG_000597"
     CDS             complement(11252..11476)
                     /locus_tag="ACL8CG_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGS1343244.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11554..12297)
                     /locus_tag="ACL8CG_000598"
     CDS             complement(11554..12297)
                     /locus_tag="ACL8CG_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1343245.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12297..13097)
                     /locus_tag="ACL8CG_000599"
     CDS             complement(12297..13097)
                     /locus_tag="ACL8CG_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1343246.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13255..13611)
                     /locus_tag="ACL8CG_000600"
     CDS             complement(13255..13611)
                     /locus_tag="ACL8CG_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS1343247.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13624..14136)
                     /locus_tag="ACL8CG_000601"
     CDS             complement(13624..14136)
                     /locus_tag="ACL8CG_000601"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGS1343248.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(14136..14630)
                     /locus_tag="ACL8CG_000602"
     CDS             complement(14136..14630)
                     /locus_tag="ACL8CG_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS1343249.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14765..15211
                     /locus_tag="ACL8CG_000603"
     CDS             14765..15211
                     /locus_tag="ACL8CG_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGS1343250.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15208..15855
                     /locus_tag="ACL8CG_000604"
     CDS             15208..15855
                     /locus_tag="ACL8CG_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGS1343251.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLVIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15876..16457)
                     /gene="pdxT"
                     /locus_tag="ACL8CG_000605"
     CDS             complement(15876..16457)
                     /gene="pdxT"
                     /locus_tag="ACL8CG_000605"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGS1343252.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16458..17333)
                     /gene="pdxS"
                     /locus_tag="ACL8CG_000606"
     CDS             complement(16458..17333)
                     /gene="pdxS"
                     /locus_tag="ACL8CG_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGS1343253.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17485..18864)
                     /gene="nox"
                     /locus_tag="ACL8CG_000607"
     CDS             complement(17485..18864)
                     /gene="nox"
                     /locus_tag="ACL8CG_000607"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGS1343254.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19158..20081
                     /locus_tag="ACL8CG_000608"
     CDS             19158..20081
                     /locus_tag="ACL8CG_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGS1343255.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20141..20746
                     /locus_tag="ACL8CG_000609"
     CDS             20141..20746
                     /locus_tag="ACL8CG_000609"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS1343256.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20764..22008
                     /locus_tag="ACL8CG_000610"
     CDS             20764..22008
                     /locus_tag="ACL8CG_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGS1343257.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22104..22361)
                     /locus_tag="ACL8CG_000611"
     CDS             complement(22104..22361)
                     /locus_tag="ACL8CG_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGS1343258.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22403..24439)
                     /gene="glyS"
                     /locus_tag="ACL8CG_000612"
     CDS             complement(22403..24439)
                     /gene="glyS"
                     /locus_tag="ACL8CG_000612"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGS1343259.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24651..25568)
                     /gene="glyQ"
                     /locus_tag="ACL8CG_000613"
     CDS             complement(24651..25568)
                     /gene="glyQ"
                     /locus_tag="ACL8CG_000613"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGS1343260.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(25936..26697)
                     /locus_tag="ACL8CG_000614"
     CDS             complement(25936..26697)
                     /locus_tag="ACL8CG_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS1343261.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26970..27812)
                     /locus_tag="ACL8CG_000615"
     CDS             complement(26970..27812)
                     /locus_tag="ACL8CG_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGS1343262.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(27926..29317)
                     /gene="pgdA"
                     /locus_tag="ACL8CG_000616"
     CDS             complement(27926..29317)
                     /gene="pgdA"
                     /locus_tag="ACL8CG_000616"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGS1343263.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDVSKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29555..29923)
                     /locus_tag="ACL8CG_000617"
                     /pseudo
     CDS             complement(29555..29923)
                     /locus_tag="ACL8CG_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            30180..31157
                     /locus_tag="ACL8CG_000618"
     CDS             30180..31157
                     /locus_tag="ACL8CG_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS1343264.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFADHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            31154..32236
                     /locus_tag="ACL8CG_000619"
     CDS             31154..32236
                     /locus_tag="ACL8CG_000619"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1343265.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(32300..33335)
                     /locus_tag="ACL8CG_000620"
                     /pseudo
     CDS             complement(32300..33335)
                     /locus_tag="ACL8CG_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(33719..34915)
                     /gene="tuf"
                     /locus_tag="ACL8CG_000621"
     CDS             complement(33719..34915)
                     /gene="tuf"
                     /locus_tag="ACL8CG_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS1343266.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(35837..36706)
                     /gene="gla"
                     /locus_tag="ACL8CG_000622"
     CDS             complement(35837..36706)
                     /gene="gla"
                     /locus_tag="ACL8CG_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGS1343267.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(36929..37450)
                     /locus_tag="ACL8CG_000623"
     CDS             complement(36929..37450)
                     /locus_tag="ACL8CG_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1343268.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKKDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(37408..38513)
                     /locus_tag="ACL8CG_000624"
                     /pseudo
     CDS             complement(37408..38513)
                     /locus_tag="ACL8CG_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(38624..38878)
                     /locus_tag="ACL8CG_000625"
     CDS             complement(38624..38878)
                     /locus_tag="ACL8CG_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343269.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(38872..39114)
                     /locus_tag="ACL8CG_000626"
     CDS             complement(38872..39114)
                     /locus_tag="ACL8CG_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343270.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(39236..40081)
                     /locus_tag="ACL8CG_000627"
                     /pseudo
     CDS             complement(39236..40081)
                     /locus_tag="ACL8CG_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            40315..42033
                     /locus_tag="ACL8CG_000628"
     CDS             40315..42033
                     /locus_tag="ACL8CG_000628"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGS1343271.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLTDGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            42144..42491
                     /locus_tag="ACL8CG_000629"
     CDS             42144..42491
                     /locus_tag="ACL8CG_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS1343272.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(42769..43605)
                     /locus_tag="ACL8CG_000630"
     CDS             complement(42769..43605)
                     /locus_tag="ACL8CG_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1343273.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(43618..44247)
                     /locus_tag="ACL8CG_000631"
     CDS             complement(43618..44247)
                     /locus_tag="ACL8CG_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1343274.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(44257..44898)
                     /locus_tag="ACL8CG_000632"
     CDS             complement(44257..44898)
                     /locus_tag="ACL8CG_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1343275.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(45044..46273)
                     /locus_tag="ACL8CG_000633"
     CDS             complement(45044..46273)
                     /locus_tag="ACL8CG_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGS1343276.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELANLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(46263..47429)
                     /locus_tag="ACL8CG_000634"
     CDS             complement(46263..47429)
                     /locus_tag="ACL8CG_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGS1343277.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            47573..48586
                     /locus_tag="ACL8CG_000635"
     CDS             47573..48586
                     /locus_tag="ACL8CG_000635"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGS1343278.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(48631..49050)
                     /locus_tag="ACL8CG_000636"
     CDS             complement(48631..49050)
                     /locus_tag="ACL8CG_000636"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGS1343279.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(49061..50467)
                     /gene="atpD"
                     /locus_tag="ACL8CG_000637"
     CDS             complement(49061..50467)
                     /gene="atpD"
                     /locus_tag="ACL8CG_000637"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGS1343280.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(50553..51431)
                     /locus_tag="ACL8CG_000638"
     CDS             complement(50553..51431)
                     /locus_tag="ACL8CG_000638"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGS1343281.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(51447..52952)
                     /gene="atpA"
                     /locus_tag="ACL8CG_000639"
     CDS             complement(51447..52952)
                     /gene="atpA"
                     /locus_tag="ACL8CG_000639"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGS1343282.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(52967..53503)
                     /locus_tag="ACL8CG_000640"
     CDS             complement(52967..53503)
                     /locus_tag="ACL8CG_000640"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGS1343283.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(53503..53997)
                     /gene="atpF"
                     /locus_tag="ACL8CG_000641"
     CDS             complement(53503..53997)
                     /gene="atpF"
                     /locus_tag="ACL8CG_000641"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGS1343284.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(54011..54727)
                     /gene="atpB"
                     /locus_tag="ACL8CG_000642"
     CDS             complement(54011..54727)
                     /gene="atpB"
                     /locus_tag="ACL8CG_000642"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGS1343285.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(54762..54962)
                     /locus_tag="ACL8CG_000643"
     CDS             complement(54762..54962)
                     /locus_tag="ACL8CG_000643"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGS1343286.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT        16348 a        12158 c         9963 g        16615 t
ORIGIN      
        1 tctgccgttc tcaaagcgtt tatatagtag ccaaaatcct tgaccatccc agtaaagggc
       61 tttaaagcgg tctttacgtc caccacaaaa gagaaaaact tgaccggaga aaggatccaa
      121 ttcaaagtgg gttttaacca gataagccag tgaatcgatt ccttgtctca tatcagtctt
      181 cccacacacg agatagacct gccctaggct agatagatga attgtcatag agcaacacct
      241 tatccaaaag ctgttctacc atttcgagat tgagagattg aaaaaaactt acttcaagct
      301 tgccaatacg aattttaagc agaatatcat ttctcttttt agaatcaaaa ggacgagatt
      361 gtggaatctc tacaggaaca ataggttgtg gcattaaaat atcctccaat agttttactt
      421 tactaatagt atacaggagg aactccatga atgatagata ccttgttatg acgcgcttac
      481 tatattagaa agttggctct ctaattaaat taattctcat tatatatatc aaaagaccgc
      541 agtttgaaaa ctacggtcta attttttgtc caaatgtaaa tcacttggaa ctattattca
      601 atttattctt tttagtaaat gttcccgttt taatcccagt tacagttttt aatcctctgt
      661 aaccgttgat tttacaaagc ttttaatttt tttgcgatta ctcccactca actgttgcag
      721 gtggtttact tgtaatatcg tagacgatac ggttaacatg atccacttca tttacgatac
      781 gcactgagat tttttgaagt acttcccatg gaattttggc aaaatcagca gtcataccat
      841 cgatagaagt gatagcacgg attgcaatcg tgtagtcata cgtacgaccg tcacccataa
      901 caccgactga acgaacgcct gtgttaacag tgaagtattg ccaaatatcg cggtcaagtc
      961 cagctttagc gatttcttca cgaagaatag cgtctgattc acgaacggtt tcaagtttct
     1021 cttcagtgat ttcacccatg acacggatag caagtcctgg tcctgggaat ggttggcgcc
     1081 atacgatatg gtctggcata ccaagctctg taccaagagc acgaacttca tccttgtaaa
     1141 gagtattgag tggttcaatc aattcaaact gcatatcttc tggaagacca cccacgttgt
     1201 ggtgtgactt gatagtttga gctgtatccg taccagactc gataacatct gtatataaag
     1261 taccttgagc aaggaatttc acatctttga gcttgcttgc ttcgtcatcg aatacataga
     1321 caaactcgtt accaatgatt ttacgttttt gttcaggatc agaaacgcca gcaagtttgt
     1381 caaggaaacg tttagcagcg tctgctttga cgatattcaa accaaactta ccaccgagca
     1441 tgtccataac ttgatcagct tcgcctttac gaagaagacc gtggtctacg aagatacaga
     1501 tcaattgatc gccaatcgct ttttggagaa gaaccccaac gacagatgag tcaacaccac
     1561 ctgatagacc aagaaggaca cgtttatcac cgacggtttc acgaattttt ttgatctgca
     1621 tgtcaatgaa attatccatt gaccagtcac ctttagcctt acaaatgtta agggcaaagt
     1681 tacgaaggat atcatttccg tatacagaat gacgaacttc tgggtggaat tggataccgt
     1741 aaatgtgttt atctgggttt tcgatggctg cgtatgggca gtcagctgat gtacctgtac
     1801 gaacaaagtc agcaggaatc tcagtaaccg catcaccatg gctcatcaaa acagtctgtt
     1861 catcaggtgt tgattcaaaa agcgctgatg gtgtgtgagt tagggttgat tgaccgtatt
     1921 cacgatttcc agcatcacct gcaggaacaa cttttcctcc aagtttatgg gtcaataact
     1981 gcataccata acagattccc aaaattggaa ttccgagttc gaagatttct gggtcaatat
     2041 caaatgaacc atcttcatat acagaatttg gaccacctga tagaataatt cctacaggat
     2101 tgacttcacg aacttcagca gctgaaattt tatggctttt tagttctgaa aaaacaccaa
     2161 tctcacggat acggcgtgaa atcagctggt tgtactggct accatagtcc aatacgatga
     2221 ttttttctac atcttgcaaa tcagttgaaa tgttgctcat ctttttcctt tctcaaaaga
     2281 aatatctttt ctcaatattc tatcacaaat aagggcgaat taccaactaa acaaggcgaa
     2341 gtttgacttt ttctagttta ttggggtaca atagagaaaa gatagaaatg aagtgaaaaa
     2401 tatgctacct gcttatatga aaatccatga tcagataaaa aaggatattg acgagcaccg
     2461 ttgggctatt ggtgagaggc ttcccagtga aagagattta gctgagcagt ttgcggtcag
     2521 tcgcatgacc ctccgccaag ccgtatctct attagtcgaa gaaggcgtct tagagcgccg
     2581 tgtaggaagc ggcacctttg tttccagtac tcgagtacaa gaaaagatgc gagggacaac
     2641 cagttttact gaaattgtca aatcccaagg taaagttccc tctagccagc tcatttccta
     2701 caaaaaaacc attcccaatg agcaagaagt tgccaagcta ggaatttttc caacggacaa
     2761 tattatccga atggagcggg tccgctatgc cgaccaagtt cccctagttt atgaagttgc
     2821 ttctattcct gaaaaattca ttaaggactt taaaaaagaa gaaatcacca gtcatttctt
     2881 ccaaaccttg caaaaacatg gctatcgtat cggtaaatcc caacagacca tctatgctcg
     2941 ccttgctaaa gaaaagattg cccactattt ggaagttgaa aaaggacatg ctattcttgg
     3001 attgacccag atttcctacc tagaagatgg tactgctttt gaatacgtaa aaagtcaata
     3061 tgtaggcgaa cgctttgaat tttatcttga aaataattag attaccacgc aaaaactctc
     3121 tgtcacggac aaagagtctt ttttattttt ctaagaataa atctttcaaa gaaatcaaag
     3181 ttacagcaaa caatatcatt gccataccaa gaaaatcaat gggataaaat tgttcattca
     3241 ttattaagaa ggcaaagaaa atcgccgata ttggctcaat tgaagccaac aagcttgact
     3301 tgaccggtcc tatcagactg gctcctttaa ggaaagctgt ataggcaaag acagtcccga
     3361 taaggataat gcctgcaaac gcaaggagaa aatcaagact agtcgggata tcggcctgta
     3421 gaacccctgt aaaaggaagg gcgaccaaac ctgctatgac cattcccaca ccaatgacca
     3481 agctgctccc ccacttttta atcaaggcta tgggtaaaat gatatacaga gcataagtca
     3541 aggcagaaaa gagaccccag aacagaccag caggtgtcat ggataactgg tccaactgcc
     3601 catgtgttgc gatcaggaag gttcctccga tggcgaatat gatggaaact atctctccca
     3661 gtgtcggtgc caccctatcc ttgatacagc tataaattaa aattccgaca ggacaaacat
     3721 actgaagcac cgtcgctgtt cccgcattgg tctcctgaat agcagacaga taggcgaatt
     3781 ggttgagaaa aagaccaatc agagcaaaaa taagaagaga cagcaaactc tttctatcct
     3841 ttaaaaagac cagtatttta tcctttgcag tagcataagc caagagcatg agaattccac
     3901 cagcgattaa aagacgcaag ttagtcaaga ccagagccga aattccgtgt gccattaggt
     3961 attggccact cgttcctgac accccccaag caataccagc cacaactgtt agtaaagtcc
     4021 cttttaaact atttgacatg tctctcctta ctcttctttg cgaatcaagt tcatcacttg
     4081 attgcggtct aatatccatt gagctctctc gtccttttca taggtacgat tcgataggaa
     4141 aatagtggct tcttgcttct gacgattcca catgataaag gtacctgtat agcccgtatg
     4201 gtctagccaa tctccttcca aattccatgc taaagaacgt tccttgtcat ccaaaggaga
     4261 aaaattttga tttaagtctc ttgcaaaatc atctgctaaa tagtgttcta aaaagatttg
     4321 taaatccttt atagtcgaaa ataaaccagc actcccagca tgtctaccca ggagacgagc
     4381 cttgggatca tgcactatgc ctgcctctac acctctaact gttggaacag caagctcaac
     4441 tggcccaaac ttggtttccg tcattcccca aggtttccag acttgatcct ttaaaatcac
     4501 atccaaatct tgattaaaaa ttctttccaa aataaagccc aacagcaaaa aatggacatc
     4561 cgaataaaga aaggctggct gacttcgtct gttgagatga aacatcgctt cctttaattc
     4621 aggggctgtt aaaagatcac gattaggaat aaaaggatca aggtctgttg catgagtcaa
     4681 gagctggcga atagtgatgt ctggataatc actctcaggt aaaaaatcta ttaccagtct
     4741 atcaatatct aattgaccta tttcccacaa gaaggtacaa actgtgccaa ccccaacaac
     4801 cttgctgaca ctagctaggt cataaactag tcctgcctca gtctgcaagc catgctctgg
     4861 gtcactctgg cctaaataga actctgtcca ttgattgtcc ttaaaatacg caaaagaggc
     4921 tccgggataa atccctgcct cgatttgttc ttctattttt ttaataatct tggtccactt
     4981 catacttctt caaaccacaa ttcaacatta tttctatctt taccaaggaa gaatttttca
     5041 gacttaggaa taaaatattc agtagactca aacttctggc gaagacttgc tatgtctaat
     5101 tcattgacca agaacttgag catagataag tcccaggtaa ccgtattgtc cacagtcaaa
     5161 tcctgcccct gagctggaat aaaatcaagg gatgccccaa tttcagatga ttccaagaaa
     5221 ctttcgatat cagttgggag atgtaattcc atagaaatct caaatttact taaagaaatt
     5281 gatgccaaat ctgtttgaaa ttcaggcttt tctcctactt ctactagact tgctatgtca
     5341 tcttccgcat gaatcaaaat caaatcatct tctggtgaga aaatttcaaa agcgtagcca
     5401 ttttgacctt tatataatcg atgaatcgaa tctgttttag ataagattcc ttcaatttct
     5461 aagggatttt ccaccttgac aatcaatcta gctagttttt ttcttccctc taccttacga
     5521 gtacgcatac tgggagcttc ttctaaaacc agcttttcaa gacccgtttg gtcacctagt
     5581 gacagaaagg ccgattcttc taacaaggcc ttcattccaa gggtttcaat ataaaatgtt
     5641 tcatttaatt ttctattatt agcttttaaa gtaggaataa tccgtacaat ctgatttaca
     5701 ttcataaatt cctccgtcac tttttatttt aaaggatttt agaatttttt acaagatatt
     5761 atgctcaaat ttaacattat ttagctattt agtaaagata gtctttcaag gattttgaca
     5821 aagcctgata accagcaata ctgaggtgca gtccatcagt tgtatattct tttttgagtt
     5881 ggcctgcttg gtctgtcaaa caatcaaata ctggcacaaa ttccacctgc atataggcag
     5941 atgcaagctc ttgataggct tgattccagt tctgaatttt ttcattcgag cggatataga
     6001 ctgcctgctg gtactcctct ctctcattga caggcaaaat ggaaagcaat ttaatctctg
     6061 tcaatggata atcgcgagca acggattgaa tgatagcttc gagattattg agagcctcat
     6121 tcacaggaac atcctttccg atatcatttg tcccaatcag aagaaaaatt ttatctactg
     6181 ctccaccata tagatgagca tcaaggttct ctagtaacag tcctgtctga tagccacgaa
     6241 ttcctcgatt gacaatcgtc tttgaagtcc caaatagctc ctgtagagga taatactcga
     6301 caatggaatc cccaataaaa agaatgtttg gttctacaac agaaatgtga tttaggtgac
     6361 gatacttagt ttgaattttt tcttgttcct ttaggagcca attttctaat aactgtactg
     6421 ccacttcatt ctcctttttc taaccagttt tccaagactt gataaactcc tccttggctg
     6481 ttggctggtg ctagagcagt cgccacagct ttggctttct catcagcatt ttccatcgca
     6541 taggcaattc cagccatttc aagcatttca acatcatttt cactatcacc aaaagccatg
     6601 atttcttggg atttcaagtc ccagcgcttg agtaattcct ccaagcccca tgctttatga
     6661 atcccagctt ggaggatatc aatgcaacca tagccactgg atacagctcg gacacggcca
     6721 tcaaagagag cattgatttc ttccaaaacc gaactcaaac gttcctcacc aacaaccatg
     6781 ctcatcttga gcacaccacc aaagaggtca gatgttaatt catccacaaa ttgcatccgt
     6841 tggtagaatt tttcaatcat ttctggagtc ataaaacttt caagatctgt aaaaatcgta
     6901 ccttccttga caaaatcacc cttcatcccc gttacaacaa actggtcctg acacgctcga
     6961 cccttgaaat gagtcaaagc cttgttgaca atggcgtcat cccatgtctg agcctgaatc
     7021 aattcattgt tttcaaaaat acgagcgcca ttagcaacaa ccagaaccac tcgatccacc
     7081 aagggactca gtagttgtct catgcggtga atttcattgc ccgtcgcaat gacaaaacga
     7141 atgccccttt gatccaactg atctaaaatc ttttccaatc gtgggagatc aagctgacct
     7201 ctagcatcca gcaaggtccc atccatatct gtcgcaatta ccttaatcat catttacttt
     7261 cctctggatt caagctaata ccacttcaat cccacatgtt cattcatttc tttataggct
     7321 gtatcaattc gttccttagt cgcttcatct aactggtcac gatgactgcc atcctctata
     7381 aaatcttcca aaatataagt ttggtaatga tacaagggat atccttctgg tgaaaaggtt
     7441 ccctttggtg ttcgattgac ccaagtagga tgagctttag ctgttccgat agttgttttt
     7501 ccatccttct tcttgatggt gacatccatg agaacaccac gttcagtcca cttagcattc
     7561 tcttcatctc ccatagattc aattcgttga ttggaaatga agttccccat ttaatagata
     7621 atgagtttct tatctccatc tttttcaacc gtttcagatg gttcaacaac gtgaggatgc
     7681 cctccaaaga taatatccgc tcccaaatcg atcatcttgt gataaagagc tttttgttct
     7741 tcagttggtt ccaatcgata ctcaacaccc atctgaagca tgataatggt gatatctgct
     7801 tccttctctg cccgttcaat ttcaaccttt atcttatctt cgtttaaata tgaaagataa
     7861 cgattatagt cttcctgaga aatatactgc tcaattccat tgaaaccata ggaataggct
     7921 aacaatgcaa ccttgatacc attcacttcc ttaatgacca gcggagcctg atcacgtggt
     7981 tcgtgcgtat aaactccgat tggagtgatt ccagctttct caataatatc ggccgttgaa
     8041 ataactccct caatttgcga atccaaaata tgattatgag ctaaatccag cacatgataa
     8101 cctgcctcct taatagcatc cataacttca acaggagcat taaagagaag ataacccgct
     8161 aaataatgat ccttattaat ggttccttca aaatcaccaa tagctaaatc tgctgcttag
     8221 tccccttgct tgagccaagg agtcacatac tcaaaatttt catgaaagtc ataggtaccg
     8281 tcttcttttt tagctgaaaa gaaaagtcca tcgtggtaga gcaaatcccc gtgggccata
     8341 attctggcag ttttttcctc ttcctactcc tgagactttt gcttagtccc ctcttgagaa
     8401 atagtatctc gtttttgact agtcaaggga ttccttggaa gctttcaaac aacaagacca
     8461 agcccattga taaaccaact gctagcaaga gtatcgccac aaatccctta ttgctccact
     8521 tgcgataact cctaaaaagt ttaccaagcc cttcataaaa cgaaaagcta aaccaccctg
     8581 atttcgattt tgtcttcttt gtatcttcgt tctccctact ttcttatgca agccttttct
     8641 ttttattata tcacagataa gtatttcttt cacaattgaa ttgaacttcc catctatttt
     8701 ctataaatcc taaatgccat aatgctttca attcttgtca ttttgtgata tcatgtagag
     8761 gaaatgaact aatccacagt ggcttattcc aagtatacca cttgggcttt ggcagtagct
     8821 aactgcacta aacataatat aaggagagaa aatgtctgca atagaacgta ttacaaaagc
     8881 tgctcactta attgatatga acgatattat ccgtgaaggg aatcctactc tacgcacggt
     8941 tgctgaggaa gtcactttcc ccctatctga ccaggaaatc atcctaggcg aaaagatgat
     9001 gcaattcctt aaacattccc aagatcctgt catggctgaa aaaatgggac tccgcggtgg
     9061 tgttggactg gctgctcccc agttagatat ctcaaaacgc attatcgctg ttttggtacc
     9121 taatattgtt gaagaaggcg aaactccaca ggaagcctac gatttggaag ccattatgta
     9181 caatccaaaa atcgtctctc actctgttca agatgctgct cttggcgaag gagaaggttg
     9241 cctgtctgtt gaccgtaacg tgcctggcta tgttgttcgc catgcccgcg ttactgttga
     9301 ctactttgac aaagatggag aaaaacaccg tatcaaactc aaaggctaca actccattgt
     9361 tgttcagcat gaaattgacc acattaacgg tatcatgttt tacgatcgca tcaatgaaaa
     9421 agacccattt gcagttaaag atggtttact gattcttgaa taaagaaaat cccgttgcaa
     9481 gacggggttt tgtgttataa tagaggcatg aaaacaaatg atattgtcta tggtgtccac
     9541 gccgttaccg aagctctcct tgcaaataca ggaaacaaac tctacctcca agaagatctc
     9601 cgaggtaaga atgttgagaa agtcaaggaa ctagctacag aaaagaaggt gtccatttct
     9661 tggacatcaa aaaaatctct ctctgagatg actgaaggtg ctgttcatca aggttttgtt
     9721 ctacgagtgt ctgaatttgc ctatagcgag ctagattaca tccttgcaaa aacacgccaa
     9781 gaagaaaatc cacttctatt gattctagat ggtctaaccg atccccataa tctgggttct
     9841 atcttgcgaa cagccgatgc gaccaatgtt tcaggtgtca tcattcccaa gcaccgtgct
     9901 gtcggagtaa ctcctgtcgt tgccaaaaca gccacaggtg ctattgaaca cgttccaatt
     9961 gcccgagtga caaacctcag tcaaacctta gataaactca aggatgaagg cttctggacc
    10021 tttggaacgg atatgaacgg tactccttgc cacaagtgga atacaaaagg gaaaatcgcc
    10081 ctcatcattg gaaatgaagg aaaaggtatc tctagcaaca tcaaaaaaca agtcgatgag
    10141 atgattacca ttccgatgaa tggacatgtt caaagcctta atgccagtgt tgctgcggcc
    10201 attctcatgt acgaagtttt ccgaaataga ctataaaaaa gtttccagtc atctgattgg
    10261 aaactttttt atgattaact atgttctgtg ataaacttgt aggcttcttg accagcgata
    10321 gctccatctc caactgctgt tgttacttgg cgaaggtctt tcaagcgaac atctccaact
    10381 gcaaagatac cgtcgactgc agtcttcatg tggctatctg tcacaatcca gcctgcctga
    10441 tcttggatat tcaattcttt aacaaaatcg ctaagagggt ccaaaccaac atagataaag
    10501 acaccaccga aggcttgttc tgtcacttga cctgttttca cattttcaaa tacgactgat
    10561 tctactcggt tttcaccctt gatttccctt actacagaat cccagataaa gctgattttt
    10621 tcattcgcaa aggcgcgatc ttgtaaaacc ttttgggcac gaagttggtc acgacggtga
    10681 acaatggtaa cagtcttagc aaaacgagtc aagaagaggg cttcttcaac agctgaatct
    10741 ccaccaccaa ctatcaataa atcttggtca cggaagaaag caccatcaca cacagcacag
    10801 taagaaacac cacgactgtt cagttcttct tctccaggca ctcccaaagg acggtgttta
    10861 gaaccagttg ctacgataac tgtacgtgtt tcatatgttt ggtcatcagt catcactttc
    10921 ttaaaatcac catggtcttc gacattttca acataaccat aaatgtgctc aacaccaaga
    10981 ttttcaagtg gttcaaacat cttttcagcc aattcaggtc cactaatatt agcgtatcct
    11041 gggtaatttt cgatatcaga tgtattattc atctgaccac ctggcagacc accttcaatc
    11101 aaagctactt ttagattgct tcgagcagca tacaaggccg cagtcatccc tgcaggtcca
    11161 gcaccgataa taatagtatc gtacatatag attccttctt tcttgttgta actatcttta
    11221 ttctaactct ttcttgtcaa tcacgcaagg attatgcctt gaaaacaaga attaaactca
    11281 taaccgcaaa ggataatact gggacaacca agactccaat cataatcata tcatagagat
    11341 gggcttggcg agccttggct gtcttatcaa ctcccgacat ggctctcaga ccaatccaaa
    11401 tccctaaaaa aatcagaaca aggatggtgg tcaatatcaa actctcgaaa tataaagaaa
    11461 atagttgcag tagcatgatt tctctcattt ctatcttttt taaagagtaa actcagctag
    11521 tccaactaac tgagttttcc tttatctatt atatcaaata taagtccgtt tgtaactagc
    11581 gaagaattct tttgtccgct cttctttagg ggtgtggata atctcatccg gagttccaga
    11641 ctcgatgatt ttccccttat ctaagaagag aatcttatcc gcaacttggg ctacaaagga
    11701 catgtcatga ctgaccaaaa tcatggtctg acctgactta gcagcatctg caatagactt
    11761 ttctacttca ccgaccaatt ctgggtcaag ggctgaagtt ggttcgtcta agagcaaaac
    11821 atctggtttc atagcaagcg cacgcgctag ggcaacccgt tgcttctgtc cacctgataa
    11881 atggcgagga taatggtttt cacggtccga aagcccaacc ttagccaact cttccttggc
    11941 aatcttagtc gcttcttggt cagataattt cttgacaaca accaagcctt ctttcacatt
    12001 atcaagtgct gttcggcgtt caaacaaatt aaactgttgg aaaaccatag acaacttacg
    12061 gcgtagggca aggatttctt cttgagtgat tttagaaaaa tcaactgaaa aaccatcaat
    12121 ctgaatagag ccactgtcag gtgtttcaag ataattgaga ctgcgaagaa aggttgattt
    12181 tccagctcct gaagaaccaa tcaaggctac aacttcccct ttttgaatat ccaagtccag
    12241 atgatccaag acagtctgtc ctgaaaagga tttgcttaaa ttcgaaatct taatcattaa
    12301 cgaaggtctc ctttcacatc tgtttgcact gtatcaggtg cagaaatagc catttttctc
    12361 tcgatgaaac gaccgaggct ttcaattccg atattgacta cccaataaac aagggcaacg
    12421 gagatgaagc gttcaaaata gcgataatca gctccaccta gaatctgagc ttgggcaaag
    12481 acttccacaa cacccgcact aaaagctaga gatgttccct tggtcaaacc gatgagggaa
    12541 ttaatcaagg ttggagtagc taccaccgct gcattaggaa taatcactcg tcgataaact
    12601 tgcgctcggg tcatacccag actgcgtgcc gcctcaatct caccaggatt aactgagaga
    12661 atggctgcac gaatggtttc actagcataa gctgcctcat taaaggcaaa agcgacaatc
    12721 gcaaaagctg cagctggaat cgcattgata ttgagaccag ttccccattg ctgattgagg
    12781 gctttcaaag ccaaagggat tccgtagtag gtcaacatga gttgcaccaa aatcggtgtc
    12841 ccttttaaga aactaacaaa gaaggcctgc aagggatata aaatcttgac acgattgatc
    12901 ttcacaatgg caaaaagaag cgccaaaacc aagccaaaaa gggcaccacc aattgtcaac
    12961 ataattgttg ttggaagttg ttggacaatt ctagggattc catcaaagac cgaacgtagg
    13021 ctaaacagct tgccatccgg aatcaattgc atcaagtttt ggtaccaatc tgatgctaaa
    13081 atcgttgtaa cattcataaa aacatcctct tctgataatg attcattcta ccatgcttct
    13141 gccgtcaatg aaattatttg ctacggtcag atacagactt tgtctaccta ctagtttatc
    13201 atactttgaa acagggaagt tatatatttt atctatcaaa gagatagata aaaactattt
    13261 cagtcccagt tcttcataag attttcgata accgatttgc ttaacagttc cattttctac
    13321 taaaatgggc cgttttaaca acataccgtc acttgctagc aactcagccg cttcttggtt
    13381 tgacaaactt cctaccttat cttttagccc taattcacgg tatttgatac cactggtgtt
    13441 gaaaaattgc ttcaattcaa atcctgaggt ttctagccaa ttcaaaatga cttcttggct
    13501 aggtgtttct tccacgatat ggacggcttt atagtccaca cctaattgat ttaattcttg
    13561 ttttgctttt ttacaagttg aacatttggg gtattcgata aattctaaca tgtgcttctc
    13621 cttctatttg tttatatctt taaaatctac gccttcatgc tccaagagcc aagctttctt
    13681 ttccactcct gcagcatagc ctgtcagacg cttgcctgct cccaacacac gatgacaagg
    13741 tactaggata gaccaaggat tgcgtcccac tgctccacca attgcttgag cagaagccac
    13801 ttgcaggtct tgagcaattt gtccataggt cactgtctga ccataaggaa tgccctgtaa
    13861 atagtcccaa actctctttt caaaattcgt tccgattggc gccaagagca agttggataa
    13921 atcctgaggc ttgcctttaa agtaatcatc taagcaagca ataactgggt ctaaaatagg
    13981 atgactaaca acttcttcta tcgtttcatc tcctagtccc ctctcaaaat gcttctgctc
    14041 ctgaacccaa attccataca aataatggtc atcagctaca agtgatagaa taccaattgg
    14101 tgaggagtag agtattttta catacttctt ttgcattatt tctttaattt ttgataggcc
    14161 aagcgttcgc catctactgg caccttacca acttgtttaa aaccaagttt ttcaaaaata
    14221 tgttgcataa ccttgttttc agcatgcgta tctgagcgaa aatcaagata atcaaaacct
    14281 tcaatcaagc cctctaagaa ggtttgagca actccttttc cctgcacatc tgctgccaca
    14341 gcaatacggt gaaagactag atactctgac tctccagctt gccagtttcc ctcataaata
    14401 gcttcatagg cctcctctgg actcttggtc acagcagcat aggctagcag ttctccctct
    14461 tccaaggcta cgtaggcttg ccctgagatg atatcatcga taataacatc tgcatttgga
    14521 tagccatttt gccactggtc actaccagca tctgctaaac attttttggc atcctccatc
    14581 acctgcatga tggcatctac ttcatttgga aaagctaaac gaatttccat cttttttcct
    14641 catttctgac tagtttctcc catcatagca taatttaagt atttctacaa gcagttaaaa
    14701 cttgactttg tgtttttgtt attttataat ctagttatca aaactatata aaaaggagtt
    14761 gaaaatgaaa actacctttt cctacccaaa atgggcagaa attccaaaca ttgacctcta
    14821 tctggaccag gttttgctct atgtcaatca ggtctgcgcc cctatctctc ctaataaaga
    14881 caagggccta acagcatcta tggtcaacaa ttatgtgaaa aatggttacc tgacaaagcc
    14941 tgacaaaaaa aaataccaac gccaacagat tgcccgtttg attgctatca caaccctcaa
    15001 gtctgtattt tctattcaag aaatagccca gacacttaac actctacaaa ctcaagcaag
    15061 ttcagaccaa ctctacgatg cttttgtgga ctatatgaac caaggaattg acccagctaa
    15121 ccctattatc caaaccagct gccaaaccgt taaactctat catcaaactc tagacttaat
    15181 cgatcatact caagaggagg taatccaatg aacactagtc ttaaactcag caaacaactc
    15241 agttttggag aggagattgc taatagcgtg acccatgctg tgggtgcagt catcatgctt
    15301 atcttgctgc ctatttcatc catctatagt tatgaagcac acggattttt atcctctatc
    15361 ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc tatcatccac catttatcac
    15421 tctatggcct atggttcgac ccacaaatat gttttgcgaa tcattgacca ttctatgatt
    15481 tacgttgcca ttgccggctc atacacgccc gttgtcttga ccttgatgaa taactggttt
    15541 ggctatctga ttattgtcat ccaatgggga acgaccatct ttggtattct ctataaaatc
    15601 tttgctaaaa aggtcaatga gaaatttagc cttgctcttt acctgattat gggctggttg
    15661 gttctggtta tcattcctgc cattatcagt caaacgacac ccgttttctg gagtctcatg
    15721 gtaactggcg gactctgtta tacagttgga gctggatttt atgccaagaa aaaaccttat
    15781 ttccacatga tttggcatct ctttatccta gctgcgtccg cacttcaata catcgctatt
    15841 gtttattaca tgtaaaaaag ttgagaaatt caatctcaac ttttttcttt acacatattg
    15901 ataaagtact ggtgcaagcg cacatcatca gtcaattctg gatgaaaaga acttaccaac
    15961 atattttttt cttgggctgc aacaatttga ttgttcactg ttgctaaaat ttctacaccc
    16021 tcaccaacac tactgataat cggaccacgg ataaaggtca ttggaatctt gccaactccc
    16081 ttacattctg cttccgtgta gaaacttcct aattggcgcc cataagcatt acgctcgacc
    16141 accatatcca tagttcctag atgactctct ttctgagaag tgatttcctt agccagcaaa
    16201 attaagcccg cacaggtccc aaacactggt aagccagata gaatggcttc tcggatggga
    16261 agtagcatgt tctggtcacg taagagcttg cccatggttg tagactcacc accaggcaaa
    16321 atcaaacccg acaagtcact ctgatcttgc tgaaaatcat ctagatttct gagttctaca
    16381 ctctcgacac ctaattgatc tagcactttt gcatgttctg caaaggcccc ttgcaaggcc
    16441 aatattccga ttttcatcta ttttcctcgt tcagccatga gaatttggat ttcattttca
    16501 ttaataccaa ccatggcttc tcctaaatct tcagagattt gagctaggat ttgaggatta
    16561 cggaagttag tcacagcctt aacaatggca ctcgctcgtt taacaggatc tcctgacttg
    16621 aaaatacctg aaccgacaaa gaccccctct gcccctaatt gcatcattaa cgcagcatct
    16681 gctggcgttg caacacctcc agcagcgaaa tttacaactg gcaattttcc atgttcatga
    16741 acatattgga ccaattctac agggacttgc aaatccttgg cagcaacata aagctcgtcc
    16801 tcacgtaagt tttgaatgcg gcgaatttcc tgattcatca tacgcatatg acgaacagct
    16861 tggacgatat cccctgtccc tggttctcct ttggtacgaa tcatggaagc accttcagcg
    16921 atacgacgca aggcttcacc caaatcctta gcaccacaga caaaaggaac ttggaattct
    16981 ttcttgtcca catggaaacg gtcatcagct ggagatagaa cttcactctc gtcgatataa
    17041 tcaatttcaa tagcctctaa aatctgagct tcaacaaaat gcccgattct gaccttagcc
    17101 attactggaa tactaaccgc ttcttggatt tccttaatca tctttgggtc gctcatgcgg
    17161 gaaactcctc cagctgcacg aatatcagcc ggaattcgtt ccaaggccat cacagctgcc
    17221 gcaccagcag cttctgcgat acgagcctgt tcaggattct gcacatccat aataacacca
    17281 cccttgagca tctgtgccaa gtttttattt agttcataac gattttcagt catttgtttt
    17341 atcctcatca tttgtattgg tagctacctt ttcattttaa gtcagaacag aatgaagcac
    17401 aagataaaaa aactataatt gtatggggac agattggcta aaaattatct gaccttaact
    17461 taaggccaga tagctcattc atttctattt ttcagccgta agggcagcca ttgtgatgta
    17521 gttgtatggt ttgttgaagt gtggcaagaa gaagaggtct gtcaatgcca atttatcaat
    17581 tgtcacatgc tcttggatag caagtgagaa catgtggatt cccatgctaa ttgcaatatc
    17641 atgtgaaacc atttgggcac caagaatttc acggctatct ttgtcaaaga caatcttaat
    17701 tgctacttca tggttgtcat gtttcatgaa ttctggtttt tgaagatcgt taaagcctgt
    17761 ttcagttgcg ttgtaaccag cagctttcgc tttttcaaga gtcaaaccag ttgaaaccat
    17821 gtgaagaccg tagattgaga taccatttga accttgaaca ccgattcctt ccaattcatg
    17881 tccacaagca ttgtaggcac caacgatacc agtgcgaaca gcatttgaag caagagcgat
    17941 atagcttgta tctttacgag cattgtcata aacagtcgca cagtcaccaa cagcgtaaac
    18001 gcctgggata gatgtttctt gtttcttgtc tacaaggaag gcaccgttgc ggaagagttc
    18061 gatcttacca tctgcaaggg ctgtgtttgg acggaaacca actgcaagga taaccatatc
    18121 cacgtcaaag ctttctttgt cagtaatcaa gcgttcaact ttaccgtcac cttcgattgc
    18181 tttaacagtt tgacctagag ccaagcggat gttgtgatct tccaagttct tcgccatcat
    18241 ttgtgtgaag tctttgtcat agtaaccgtt caagacagta tcaacgatat caacaaggac
    18301 aacttctttt ccaagacgtt caaaggcttc agcaagttca acaccgatgt aaccaccacc
    18361 aacaacggcg atacggtcga ggtgttggct cttgtcagaa agtttattga taacttcttc
    18421 agcattttgg tacaatttca cgaattgtac gttttcaaga gttgctttaa attcgcggtt
    18481 tcctttaaca atttcaacac cttcgattgg tggcaagatt ggtgtagaac ctgtagcgaa
    18541 aatcaatttt tcgtatgatt ctttgtgctc ttttccttca acttccgctg taactacttt
    18601 gttatcatag tcgattgaaa gaacaggtga gttcatgtaa actttagcac ctttagcttc
    18661 caatttttct ttatcagaat agaacaagcc ttcagcaccg tcaatttgtt caccaatcca
    18721 aagagccatt ccacatccta ggaaagagat gttagagttt tggtcaaata caacaatttc
    18781 gttctcattt ccaaaattat ccaacatggt attgatacat gctgtaccag cgtggttagc
    18841 accgactaca acgattttac tcataaaaat ttcctgcctt cattctaaat ttaccttact
    18901 agtataccat ttaccgttag cgtttacaag gggggtacta ttatttcagc attttttatc
    18961 aaaaataatt ccccatttat cctgttttca agcctgatga attttatgag catatttctt
    19021 gactttttcc aaattttgtt tgtgaaaatt ctaactttat ggtattataa taacatgaaa
    19081 atgaaatgta agggcttcaa tttagatgat tatttgatat tacaacttat tttctataag
    19141 agaaaggagt tggtagcttg actcttcgtt cacattctga acggctaatg gggactacta
    19201 tcactatttc attagtggat gagcaagccg atatctttct ccaaaaatcc tttgacttgc
    19261 tcaaagaact tgaataccgc ttcaacgcca atagtcaaga atctgagttg atggaaatca
    19321 attatcaagc aggaatagcc cccgtcacgg ttcatccaga cctgtttgag ctgatttcac
    19381 ttgggttaga gcatagccta gcgctctcta gccacctcaa tatcagcatt ggtcccttaa
    19441 ttcaaacctg gcgtatcggt ttttcagatg ccaaggtcgc gcagcctcaa gaaattgaat
    19501 cggtgctgcc tctaatcaat cctcatggta tcgagttaga ttcttctact tctactgtgt
    19561 ttttaaaaca gaaaggaatg aagatcgatc taggttgttt agccaaagga tacagtgcgg
    19621 ataaggttgc ccaatttctt aggaaagagg gggtgacttc tgccttgatc aatctgggag
    19681 ggaatatcct gaccattgga aaaaatcagg caagagggga taacccatgg caaatcggga
    19741 ttcaagaccc agccaatcct aggggaaatc atttaatgac catccctgtt gtcaataaat
    19801 ctgtcgtgac ttcaggcatt tatgaacgtc acctgaccgt cgatggacaa gattaccatc
    19861 acatttttga cagtcaaaca ggatatcctg ttgaaacgga actagcgagt ctaacaatca
    19921 tctctgataa atcagtcgat ggcgaaatct ggacgactcg actctttgga gaaagacctg
    19981 cttctatcct ctggcaagtc gaaagtttgg agggcatcga agtcatcctc atcgataaag
    20041 aaggccacct aagctgttct tcaggaattc ctactctata gagacaactg tttcaatgga
    20101 attttaaaat tgtattatgt aaaaagagaa aggaaatctc atgttaaaac ttattgctat
    20161 tgttggaaca aattcaaaac gttctacaaa ccgtcaattg cttcaataca tgcaaaaaca
    20221 ctttgctgac aaagctgaaa ttgaacttgt tgaaatcaag accattcctg tcttcaacaa
    20281 accagctgac aagcaagtac ctgctgaaat attggaaatt gctgctaaaa tcgaagaggc
    20341 agatggcgtt attatcggta ctcctgagta tgatcactct attccagctg ttttgatgag
    20401 cgctcttgct tggttgtctt atggtattta cccacttttg aacaaaccaa tcatgattac
    20461 aggtgcttct tacggtacgc ttggttcatc tcgtgcccaa ttgcaacttc gtcaaatctt
    20521 gaatgctcct gaaatcaagg caaatgttct tccagatgaa ttcttgctct cacactctct
    20581 tcaagcattt aacccaagtg gcgacttggt tgaccttgat gttatcaaga aattggatgc
    20641 catctttgat gacttccgta tcttcgtgaa gattactgag aaattgcgca atgcgcaaga
    20701 attgcttcgc aaagatgctg aagactttga ctgggaaaat ttgtaagata ggagaccgaa
    20761 agaatgaaat ttgttggact tgttggatca aactacgatc aatcatataa ccgcaaactc
    20821 ttggaattta tccgtcgcaa tttcaaattc aaatttgaat tagaagtact tgaaatcgac
    20881 gaagttccaa tgtttaacca agatgaaaaa tgggacgaaa gcttccaatt gcgtttcttg
    20941 tataacaaga ttacacgtgc tgatggtgtc attatcgcca ctcctgagca caaccacact
    21001 atctcagctt cactcaaatc tgtacttgaa tggctttcat acgaagttca tccatttgaa
    21061 aacaagcctg ttatgattgt gggtgcatca tactatgacc aaggaacatc acgtgctcaa
    21121 gttcaccttc gtaaaatcct tgatgctcca ggtgttaatg cctacacgct tccaggtaac
    21181 gaattccttc ttggtaaagc taaggaagct tttgataaca acggaaatat caccaacgaa
    21241 ggcactgtta aattccttga aacttgctta gataactttg ttaaatacgt aggagtcgtt
    21301 tcgaaattga aaaaaccaaa accaatcgaa tcagaagact tggattgtgg aaaaccaatc
    21361 gctacaacca tcacagaagt tgaccctgac gatccagaat gggtagaaaa agttgcagca
    21421 atcactggtg ctgtttctgg tgatacctat gtcaaattgg accacggtat cctaacagtt
    21481 aaccaaattg atatgttctt gaaagctatg ccatttgaat tgacatacgc tgacgacaac
    21541 aaccaattcc tctactacaa caacgctcac caagatccag acactatgtt cgctaaacgt
    21601 gtaccacctc aatcaggtag ccgtatgtcg actgttcatg gttctcttcc accagcacgt
    21661 atgaagaacg tagagtgggt tatcggaaca cttcgcaacg gaaaccaaga atacgtccgt
    21721 acgatcgttc caggttctcc tgcaggtgtt atcaacactc acaactacca agcaatgtac
    21781 tatcctgatg gatcatacgc tggtatcaat gaaatcgtct ttaacttcca accatggctt
    21841 gactggtacc taaaagagac tggtcaacgt ttggtgggtg gtagcggacc atttgctcct
    21901 gctgccggag gtcatggaga cgccgatgct acttctggcg cttctgattc aggggatgct
    21961 ggaggccacg gtggtgacgc agacgctaca gccggtgcaa gttactaatg atagttttta
    22021 ggaaccatta tggttccttt tttagcgaaa aaagactagc aaacacaaac tgctagtctc
    22081 tttgttaaaa gaaagagtat atattatgaa tttgggtcat caagactacg gccatgtaat
    22141 cctttttcac gttgtacttg gcgtagtttt tctggtgtaa catcgtttcc ttcttcgtcc
    22201 acaattttga ttccttcaat gtggtgacga acagcgcggc gataaccttc gatgtactcc
    22261 tcacgtagtt tggcttgttc cactttttct tctggtgtta agccttctgt ttttttcttt
    22321 ttagcaagct cattgatacg agcaattttt ttcggatcca tttcttctcc tttgtaataa
    22381 gataaagtcc gtttatcaaa ttttatttag tgttaatttg gttaaaacaa gcaaacttag
    22441 ctgctttctt ggttagttgt gacaagattg ccaaacgatt ttgacggaca gcctgatctt
    22501 cagccattac catagtattt tcaaagaaag catcaatgac tgggctaagc gcaaagagtt
    22561 gtttcaattg ctgacttgca ggtcctgata aaacgagtgt ttctactgct tctgccaaag
    22621 ctttttcttg gtcattctca aatagttctg aatcaactgt agcaacccct tctgccttct
    22681 cagccaggtt aaaggcacga gaaagtgatt caacagatgg tttaaaatct tcttccttgc
    22741 ttacttctac gagagcactt gctgcttcca acatatctgc cacaacaaag tttgaacctg
    22801 caagaactgc ttccttgata tcttttggag tagagcccat catcttatca acacgagcct
    22861 tgataaagtc cataacctct gctttatttt cataagtcaa actgtcaaat ttcaatgcat
    22921 aaaggctatc aatcagctca tccatagcaa tgtgccaacc aaaggcatcc aagatacgaa
    22981 ccacaccttg agttgcacga cgaagggcat aagggtcatt agaacctgat ggaatcaatc
    23041 ctactgagaa gaaactcaaa atcgtatcca atttgtctgc aatggctaga actgcgccga
    23101 ccttgctctc tggaagttct ccttcagctg atgtaggcat gtagtgttca cgaatagcag
    23161 ctgccaccgc tggagtttca ccagcaagaa gggtgtattt ttcacccata attccttgga
    23221 gttcgtcaaa ttcaccaacc atacctgtca acaagtcaaa cttgtaaatg gctgctgcac
    23281 gagcaaggtc aactgtttca tccactgaca aaccagcttt ttctgccaaa agtacagtga
    23341 tttgacccgt acgaatcatg tgttcacgaa gggaaccaat cttctcatgg aaggtgacat
    23401 tgtttaattt ttcaacaaga tctgaaatca ccaatttttg gtcttcacgc cagaagaatt
    23461 ctccgtcttc caagcgggct accaagactt tttcatttcc tttgatgaca tttttcaaac
    23521 gctctgcgtt tccgttacga acagaaatga agtttggcaa gagttttcca tcttgatcac
    23581 gaacaacaaa gtaacgctgg tgttccttca tagaagtcac caagacttct tctggaactt
    23641 caaggtattt agcatcaaaa cttcccatga aggcagttgg gtattcaacc aaattcaaga
    23701 cttcattcag caaatccgca tcaatttcga tacgtacacc atgttttgcc tcaatttcct
    23761 tgatttggtc aacaatcatt tgctcacgtt cacatggatc tgcgattaca aactgcttac
    23821 gaaggtcttc ttcatagctc aatgctgact gaattttggt ttctttcccc aagaaacgat
    23881 ggccacggct cacacgactt cccttgatat caaggaaatc caagtcaaac tcttgctcat
    23941 ccaagagaac agttaaagtg tggacaggac gaatgtattc aaagctattt ccagcccagt
    24001 gcatgctgac agggaaagtc aatgacttca agacatctac aacaccagga acaatggctt
    24061 caactgattg gccaacttct tccttagtga catagacata ttcttcaccc ttaatttcac
    24121 ggaattcgat atcttcaaca gtcaaacctt tcccacggac aaatccttga gctgctttgg
    24181 tgaagtttcc atcactatcc aaggcaattt tctttgctgg tcccttgaaa tcttctgtca
    24241 aatcagactg tttgtctgat aaaccagtca cacgaacagc caaacgacgt ggtgttgaga
    24301 aggtttgaat ggcttcaaaa gacaggcggt tttccttgag gaaggctgcc attttttcgc
    24361 ctagttgttt ttcacttggt gtgacaacat aggctggtaa ttcttcaaga ccgagttcta
    24421 ctaataagtt ttttgtcatg ttttttctcc gaaaagtatc tttttatttt ccagtttgcc
    24481 ttatgtgatt ggcacgcaag caaccaactt cgttgtttca ttgctaaaat tggagccaaa
    24541 agtctccaat tttgcctagt atccttagtt tcactaagga taccttcatc actgcggcaa
    24601 ctggctcagg gctcactctg ttcgcccatt ttcgtaattt gtcactctct ttattctgcg
    24661 tcttctgcta ggagtttagc tcttgtttct tcatccaaaa gtgggtagcc taggcgtttg
    24721 cgttctgcga caaaggtttt ggctacgaca cgggccaagt tacggatacg agcgatatag
    24781 cctgcacgct ctgttacaga tacggcacca cgcgcgtcaa gcagattaaa ggtatgtgaa
    24841 catttgagaa catagtcata ggcagggtgt accaagcctt cttctaatgc acgaccagct
    24901 tctttttcaa acttatcaaa gttttcaagc aacatttctt ggtccgaaat ttcaaatgaa
    24961 tattttgagt gctcatactc aggctggata aagatttctc cgtattttac accatcagcc
    25021 cactcgatat catagacaga gtctacttct tgaatgtaag aagccaagcg ctccaaacca
    25081 taggtaactt ccgcagtcac agggccagtt gccaatccac cgacttgttg gaaataagtg
    25141 aactgagtga tttccattcc gtcaagccaa acttcccaac caagaccagc tgaaccagtt
    25201 gatgggtttt cccagttgtc ctcaacaaaa cgaatatcgt gctccaaagg attgattccc
    25261 aatttttcca aagactcaag gtaaagttct tggatatttg atggagaagg cttcatgacc
    25321 acctggaatt ggtggtgttg gtagagacgg ttagggtttt ccccataacg accgtcagca
    25381 ggacgacgtg atggctctac ataagctgca ttccatggct caggtccgat agcacgaaga
    25441 aaagtgtaag gactcattgt tcccgcacct ttttcattat cataagcctg cataagcata
    25501 caaccttggt cattccaaaa ttgttgcaaa gtaaggatga tttcctggaa agtcaatttc
    25561 ttagacattg tttactcctt tttatataaa ttacttgcga catgaggctg cctcgtcgat
    25621 catacgaggc aagacgagtt agtactgcgt ctagctcagg cactctagtg ctgagcgtgg
    25681 ggcagtccga ctgtaaggag gtttctgcca ctgatgcagt gaaatgttaa tttctcagac
    25741 attgaatact ccttaataaa aaataatttc ttgcgacacg agtctgcctc gtcgattata
    25801 cgaggcaaga cgagttagta ctgcgtctag ctcagcaccc tagtgctgag cgtggagcag
    25861 tccgactgta aggaggtttc tgccactgac gcagtgaaat gtcaatttct tagacattgt
    25921 ttactccttt agtttttata tttctttttc aattaatttc tgctgaacaa accaatctaa
    25981 caagggaaaa gttttttctg tatttgccca taaatgataa gaatctaaga ccgcttgtac
    26041 actacctaaa ttttctacca acttatctac tgtcaaaaag ctgcgccagt attcataaaa
    26101 aatacttgca tagttcttat cataagtcga agaaccaaaa tcattcaatg aatgccaacc
    26161 atacttcttc tgaaaaagtt ctacgagaga ttgattacaa attttttccg cttgaaattc
    26221 ctcttctgtc aagaaatact tgcgactaat atattcaacc atcccctctt cgaaccagat
    26281 ataagagtca taaccatcaa aatcatctaa aaaatgctcc gaccaatgag ctaactcatg
    26341 tcctacaatc tgtaagagga aattttcaga taaagaatga tagtgacttt ctattgcttg
    26401 agtttgctga gaacactcgt agtccatcaa ttgatacaaa tacaactctt tccaaacagc
    26461 taaatcaggc gccataacca ttcgtctatt atttgtatag gctggaacag cgctttccct
    26521 aataatctgt gtagcagcat taaaatctga ccaaataacg gcttgcggta aatcacagac
    26581 tgcaagttca ttctttaaaa aagattgata atctttcaac ttttcagtat ttcttactac
    26641 aaaatcacga aatgtagcta gttgactatc gtcttttaca agataaaggt tgtccacggc
    26701 tctcctttct ttcacacaat agactgaata agcaaaagaa ccgcgtccga caatcctagg
    26761 ttgatttaac ctaggggcgt cagaaacgcg gttccaccct aatttattac ttcattgttt
    26821 ttgaaaatac tacagaaagc gccagctcat tattttgccc tacttggctc ccactatccc
    26881 aagctcgctt gaagaacgcc ataagacttt ctttcctgct gactattata tcaaaaatta
    26941 gaataatgta caattctttt tatgattttc tagaaatcca catcatcaac tcgtggagca
    27001 cccgattgaa cagcaatcgt ttttaaggtt tctctctcct catgactcag ttcaattcca
    27061 aagcaatcaa gattagcttg aatacgagag gttgtgacag attttggaag tggtaaaaat
    27121 ccttctgcca agctccaggc caaggctatc tgagcaatcg attttccgtg atttgctgcg
    27181 atttcttgca cttgcttgct atcaaatagt tctccctgac caaaaggccc ccaagcttcc
    27241 aataaaattc ccttttcacg acagtaagct acgacttgat cttgatacac acctggcgcc
    27301 aagcgaactt gattgaccgc aggaacgata gttgcagttt caagcaaggc atccaaatga
    27361 tggggaagaa aattgctaac gccgatagca cggattttcc cttcttgata gaggtcttcc
    27421 atcgctctcc aaacttccgc attgcgagtt ttccatgcgt cattttctct gagcggtttt
    27481 gggttcggcc aatgaatcaa atacaaatcc aaataatcca agcccagttt ttctatagat
    27541 ttttccaaag cttgacgagt ttgctcatag gtttgctgac tattccaaag cttggtagtt
    27601 acgaacattt cttcacgtgg aactccgcta tctttgattg cttgaccaac actttcttca
    27661 ttctgataaa tcgccgccgt atcaatatga cgataaccag ccttcaaggc ttctaacact
    27721 gcacgatagg cttcttctcc atccttagcc ttaaaagttc caaatcccaa tactggaatt
    27781 tctactccat tatttaattg ataggtattc atatgcttct ccttctattt tattcatcaa
    27841 ttatagcata aaacattttt taagtagtac tatcttctgt aaaaaataag tctgtcaaat
    27901 atctaacaga cctatttttt cttgcttatt catcacgact atagtacagc tcatgagctt
    27961 ttaggcgagt attgagcatc tctggtatgg tcacaaaggt ataaccttga tttttcaaat
    28021 actcaatgac ccttggcaag gcattgactg tcggactgtg aatatcatgc atcaaaacga
    28081 tagagccgtt agctacttga tgctgaattt ctgtcaaaat agatgcttca tttttactct
    28141 tccagtccag actatccaca tcccacatga taaagctcaa atccaagcta ttgcgaatat
    28201 catctgtaat agcaccataa ggtggacgca tgagtttaga actagaaccc agcactttag
    28261 ttagcacatc ctcagtatca gtaatctgct ttttagcttc atcaagagag agttgcgaga
    28321 gaatcggatg gctccaacta tggtttccaa caacatgacc ttcagatttt atcctcttca
    28381 ccaagtcctc attcccagaa acatttttcc caagcacaaa gaaagtcgct ttaatatcat
    28441 atttagctag ggtctctaat acctgcgggg tcgttgctgg atttggacca tcatcaaagg
    28501 ttagagcgac aactttttga tatttcttat caaagtaaga ttggtacaag gccgcatctt
    28561 tttcgagtaa gtacgaagat tggataacat caaagaaagc agatactggc aaggctatct
    28621 cttctaaatt ttcaaccaca ggacttggat aaaggataat ctgactatcc ttgtaatcaa
    28681 aattccatgc agacaagtct tggtcagaga agttttttac aatctgctca ctctggtctt
    28741 gctctatttt tttatcctct atgaaggagg tcaactcttt tatcagctgt tccttagcct
    28801 tactaacatc tgaaaacagt tggtcaagtg taaaaggttg cccatcttct gttaagtgaa
    28861 cctttcctag actggtcttt tcagtctctt caaccttaaa agcaactaaa tcatagattt
    28921 gtttggtcac attacgatta acgactccct ttaaacctga ctcttcttgc tctgtatagt
    28981 agaaaacaag attgtcctta ctttctagct tgtccttaac atcttgattt atcaactccc
    29041 taacagagga aatcactttc tccccttgga gaggataata ggcaatcact tcggcttgcc
    29101 cctgacgaaa atgctccttc tgatttccct cactcaattg atcatctttc tcttttttga
    29161 gcgattcaat cttttgctca aaactttttt gctggtagat cttaaaagca ataaatccgc
    29221 ctaataggca aatagaaatt gctaaaatac caatcaaagc caataataca tgtctcgttt
    29281 tcccgtgtct gccacgtcct agtctacttt tattcatatt tatatcataa caaatttgag
    29341 caataatttc aatgatacaa tttggcaatc cacaattcct ctagcaagcc aaagcatctt
    29401 acatcaactc caacatccgt atctgtagag attatgtagt tttctatcta tggaatttct
    29461 agtagattga agctagaata gtagacctat acttctaaaa cattgttaga aatcgatttg
    29521 attgtcctga tcgatttgtc ctgttcttat ttcattttac tataaaacta tgagaagcta
    29581 ggtcatctga gaagtaatta ctatcgacaa ttgcgatagc gtatactggt gcaatttgtt
    29641 tgtagctctg gtgggtatca ccttcacgtt ggcgaatttt ttctaggttt tgattaacct
    29701 gactgcacag ataagcccat aggcgattga tgaaaaaatt ctgatgatga acctgaattt
    29761 cgatgataac ttgggttcca ttatctaact ccgccaagac atctatacta gtatagaaat
    29821 cctgcgctga gtagggcatg gaaggcaaga cgtgaatgtt acttccctcc aaaatcgtca
    29881 cattttttgc tggcaagtcc agcatatcgc ggataaattg acaaagcatt agttgggctg
    29941 atacccggat gtctgagaat cctccttttc ctcctttttc tccttttcct ccttctatta
    30001 tagcacattt ttaaatctag gtttgctaga ttctatgctt ctatctattt attcggaaaa
    30061 gaaagctttt cttcagaaga aagctaatag cttatttgaa gttttctcct ctctgttgga
    30121 tagtcccgtc tatctatgtt ataatgaaag aaggatttaa aatcggaaaa ggagtattta
    30181 tgctaaaatt aggtgtcatc ggaactggcg ctatcagcca tcatttcata gaagcagccc
    30241 ataccagtgg agaataccaa ctggtcgcaa tctattctag aaaactagaa actgcagcaa
    30301 cctttgcttc tcgctatcag aatatccaac tattcgatca attagaagtc ttcttcaaat
    30361 cttcttttga tttagtctat atcgccagtc caaactcctt acattttgct caggcaaaag
    30421 ctgccttgtc tgctggtaaa catgttattc ttgaaaagcc agctgtcact caaccacaag
    30481 aatggtttga tttgattcaa acagctgaaa aaaataactg ttttatcttt gaagcagctc
    30541 gtaattacca cgagaaagcc tttactacta tcaaaaactt tttagcagat aagcaagtgt
    30601 taggagcaga tttcaactat gccaaatact cttccaagat gcctgacttg ttgactggac
    30661 aaacaccaaa tgtcttttca gaccgttttg ctggtggagc cctcatggat ttggggattt
    30721 atcccctcta tgctgctgtt cgtctttttg aaaaagctaa tgacgctact taccatgctc
    30781 aacagcttga caatagcatt gacctaaatg gagatggtat cctcttctac ccagactatc
    30841 aagttcacat caaggctgga aaaaacatca cttccaatct tccttgcgag atttatacaa
    30901 cagatggaac cttgactctc aacacgattg agcatattcg ctcagctatt tttgccgacc
    30961 accaaggaaa tcaagtccag cttcctatcc aacaggctcc tcatacgatg actgaggaag
    31021 tcgctgcatt tgcacacatg atccagcaac cagatctgaa tctctaccaa acttggctgt
    31081 atgatgcagg ctctgttcat gagctactat ataccatgcg ccagactgct ggcattagat
    31141 ttgaggcaga aaaatgaaaa ccaaactacc gactgaatgg caagaactga gtgaccaact
    31201 cggtttccaa gaattcaccc ccattcaaac tcaactattt gagctccttc ttgctggaga
    31261 aaacctccta ggagtgagcc aaaccggaac tggtaagacc ctagcgtatc tcctaccaag
    31321 tcttctcaga ctacaaaaga aaaaagccca acaactcttg attctagcac caaacacgga
    31381 acttgctgga cagatttttg atgtatgtaa aacgtgggca gaagctatcg gattgactgc
    31441 tcaactcttc ctttcaggtt caagtcagaa acgacaaatt gaacgtctta aaaaggggcc
    31501 agaaattctg attggaactc ctggccgtat ctttgaactc attaaactta aaaaaatcaa
    31561 gatgatgaat gtggaaacca tcatcctgga tgaatttgac caattactag atgattctca
    31621 gattcacttt gtagagaaaa tcactcacta cgcacctcgt gaccaccaac tggtctacat
    31681 gagtgccacg accaagtttg accaagaaaa gattgtgccg aatacacgca ctattgatct
    31741 ctctgatcaa aaattggaca atatccagca tttctacatg caggtagacc aacgtcatcg
    31801 agtggatatg ctacgaaaac tggctcatgt agaggatttc cgtggtctag tcttcttcaa
    31861 tagcctgtca gaccttggga atgccgagga aaaactacag tatcgtgata tattggctgt
    31921 ttccctcgct agtgatgtta atgttaaatt tagaaaaatc atcttagaaa agtttaaaga
    31981 taaccaacta accctgcttc ttgcaactga ccttttggct cgtgggattg atatcgatag
    32041 cctagaatgt gtcgtaaact ttgatattcc tagagatagc gaaacctaca cacaccgtgc
    32101 tggccgtact ggtcgtatgg gcaaggaagg ttatgttatc actctcgtca ctcatccaga
    32161 agaaatcaaa aaacttaaaa agtttgcaag tatccgagaa attgtcctaa aaaaccaaga
    32221 actctatatc aaataaagcc ccattgctct atacacatcc agtgtatgga gcttttttac
    32281 aagcaattca attttatact catctgtttt caaaaagcat tctagtccat ctccgattaa
    32341 cgatgggctt tatcacctcc ttctccagtc cttgtatgat atcttgaagt tgattcatga
    32401 catcttccaa agtttgaaag gctttattct taaatccacg tttacgaatc tctttcaaca
    32461 cttgttcaat ggggttcatc tctggtgtgt atggaggaat aaaggtaaaa ccaatattag
    32521 tcggaatctt taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaagga
    32581 taagcttgtg aaagctcttc taaaaaggcg ttcatccact cagtattaca tctaccagct
    32641 attaagaaaa atgattcgcc tgtatgggca tcaacagctc cataacaata gcgaaattct
    32701 cgtatatagt gactatggac atgtggacct actcctattg gagaccaaca agatcccagt
    32761 ttactgattc taccgaaacc agcctcatct tggtacatca agcgaacctt acgaaaacgt
    32821 ctactatatt taaatcgctt tcttgccttc ttgaattgag attttatttt tagacgcgac
    32881 aatggtttga gcgtctgttt tcctaggatg ttctggacgt ggcataatat ttcgccagcc
    32941 atggcgcttc aacagttgat agaaggcatc acgtgtgtag gaacgaccta actccttttt
    33001 ataagcctga aataaggcat caattgtaac aaattctcct gcctctgtag ccttcaaatg
    33061 acgggcaaga aaggctttct cttcctcaac tgtcatatat gcatggttac gaccaccacg
    33121 tgtttcttga aggagagagt cgagtccgaa ctcctcatat tttttacatt ttgctaaatc
    33181 gttgtttgat tacagtctaa aagctctata atctctttat aagatttgcc catcagacga
    33241 aatagaacga tttgaaggcg tttatgatat ttagctgtac gagagtcttt taaaagtgtt
    33301 ttgatggttt ggatttcttc tttagttgat ttcatattac tattgtataa tgctttttga
    33361 tttgagtcta gtattatact cttcgaaaat ctcttcaaac cgcgtcagct tcgccttgtc
    33421 gtatagatgt tactgacttc gtcagttcta tctacaacct aaaaacagtg ttttgagcag
    33481 tctgcagcta actttctata acaaaatgaa ataagaacaa gacaaatcaa tcaagacaat
    33541 caaatcgatt tctaacaatg ttttagaagt agatgtgtac tattctagtt tcaatatatt
    33601 atagtttgct ctttgatttt cattgagtat tagttcaata tctaaaaaaa gaaccttgcc
    33661 aagcaagatt cttttagtgt ctgacttaaa taattgttct tctgggaact aaatcgaatt
    33721 aagcttcgat ttctgtaacc atacctgaac caacagtacg tccaccctca cggatagaga
    33781 atgtagtacc ttgttctacg gcgattgggt gaatcaactc aacgtcgatt gtcacgttat
    33841 caccaggcat taccatttca gtacctgctg gaagttcgat tgaacctgta acgtcagtag
    33901 tacggaagta gaattgtgga cggtagttgt tgaagaatgg agtgtgacgt ccaccttctt
    33961 ctttagtaag gatgtagact tcacctttga atttagtgtg tgggttgatt gaacctggtt
    34021 tagcgataac ttgtccacgt tcgatttcat cacgttgaac accacgaaga aggacaccta
    34081 cgttatctcc agcaagacct tcgtcaagtt gtttacggaa catttcaaca ccagtaacaa
    34141 ctgctttttg agtttcttct ttgataccaa cgatttcgat ttcgtcgttg actttaacga
    34201 taccacggtc gatacgtcct gaagcaactg taccacgtcc agtgattgag aatacgtcct
    34261 cgactggaag aagcaatggt ttgtcagtgt cacgttctgg ttctggaata tactcatcaa
    34321 ctgtgttcat caattccata acgatgtctt cgtatttaga gtcaccttca agagctttaa
    34381 gtgctgaacc ttggataact ggaagatcgt cacctgggaa gtcgtattct gacaataggt
    34441 cacggatttc catttcaacc aattcaagca attcttcgtc gtcaaccaag tcaactttgt
    34501 tcatgaagac gataaggtgt ttaacaccaa cctgacgtga aagaaggatg tgctcacgag
    34561 tttgtggcat tggtccgtca gttgaagcta ctacaaggat agctccgtcc atttgagcag
    34621 caccagtgat catgttttta acgtagtccg cgtgtcctgg agcgtcgatg tgagcgtagt
    34681 gacgtttttc agtttcgtac tcaacgtgcg cagtgttgat agtgataccg cgttcgcgtt
    34741 cttctggagc agcatcgata gacgcatagt ctttaggttg gttaactgat gaaggcaagc
    34801 gacgtgccaa aacagttgtg atagctgcag ttagggtagt tttaccgtgg tcaacgtgtc
    34861 cgatagtacc aatgttaacg tgtggtttac tacgatcgta tttttctttt gccatttgag
    34921 taaaagcctc caataaaata tattttatag atagacagta ggcaatacag tctaactttc
    34981 cttactattt tatcaaattt cagctaaatt gcaagtgttt tacaacgttt ttgtgaatta
    35041 ttcttggtaa aaatttaact aactaataga aagtactaaa tagacttatc cttcaaggag
    35101 ttttcagcat tatccatcca ctcacttgct gaaaatgtaa acagtctctg gtttatatag
    35161 taaaatgaaa caagaatagg gcaaatcgat caggacagtc aaatcgattt ctaacaatgt
    35221 tttagaagta gatgtgtact attctagttt caatctacta tacaacctca aaactgtgtt
    35281 ttgaacaacc tgcggctagc ttcttagttt gccctttgat tttcattgag tataaaattg
    35341 cagataaaac gataacaatc ataggactca gcagagtcaa tgtaggtcga agaatagccc
    35401 ccctaatcgc ttattttata gcaaaatgaa atagaaactg aacattttgt tgaggaaggt
    35461 aaatcaattc ctcacaatgt ttgagaaaga agggaggact attccaactt caacccacta
    35521 taaagcaaac ttacaagata gggaacccat ctccgataat attccgataa tatatagtag
    35581 aatgaaaact gcacaatttg attggagaat tcaaaccaat ttctcacaat gttttagaaa
    35641 caagggtcta ttatttcaac tgcaacctac tatagcccat tgaagctgga atagcccact
    35701 aagacttcta aaccactgct ggagaggagt ttgtttagag tttctttcat ttccctaaaa
    35761 aatcaaaaag agagaaccag tctgatcctc tcttacttat agatggtgct cactcaaatg
    35821 ttaaaggagc tatttcttag agataaagga atttgaatac agctactgcc gcaattgctg
    35881 ctgcgatagg tgctactact ggtacccaag aataccacca ttttgaatcg cctttatgct
    35941 caccaagaac tgattttgga aggaaagcat gaaggagacg tggtcccaag tcacgggctg
    36001 ggttcaaggc aggtcctgta ggtcctccaa gtgatgttac caaagccata acgaggaatc
    36061 caagtgccaa gtgagccaca gaaagtcctg aagcagtgtg tggagccacc tgtgctttaa
    36121 tagccaagtc agaaaaatca actgtttgtc ctgcttctat tgccttttgt ttcatgaatt
    36181 gaagcacttc agcaccaaag aagtttttag tcaaaccaag agctgcaaag aacaaaacaa
    36241 atgaaccaac aaactcatta atcaaaccat tgacagttgc tgcatatcga ctttcttttg
    36301 taccatggtc aatacttgaa atagttgaga aagttcccaa gatgttattt ggtttttcag
    36361 ttttcaagta gaatggacgg tatgttgcca caactaaggc ttggccaaag atagccccca
    36421 agacttgcgc gataatgtaa ggtaccactt gtgcccaagg gaaaagaccg ctaactgcaa
    36481 gccctagagt gaaagcaggg ttgatgtgat tcccagatac gttaccaaac atcaaggctg
    36541 ggatcataac ccccatacca taaccaacag cgatgacgat ccagccactt tggtgacctt
    36601 tcgtaccttt aagttcaacg ttggcaactg caccattccc aagaatgatc aaaatggcag
    36661 ttcccaaaaa ttcagtggca tacttcagtg cccatgtgaa atccatttgc tagattctcc
    36721 ttaaaatttt ttagatattc cttattttat caatttttac cctatttagc aactgatttc
    36781 tggaaatatt tttaaaaaaa taggattcat agtttcccag ttcaacgtaa ttgtaagcgt
    36841 ttttattctt cacgaaagac ctcattctca aaaccaggaa aaagcccaca tctgtgatct
    36901 tttccttgtt cctagattct aaaatctatt atttttcatc ttcttttttc ttgaagaatc
    36961 ctaatcctag accagctaac aaggtcatga taccagcact agccaaggta gcattagctt
    37021 ctgtacctgt gtttggcaat tcctctctct tacctgtctc ataagtcgga acttctgggt
    37081 ctggattcac tggagtttca gtttttggag tacctggttc tggagttggt ttatctggtg
    37141 ttgataaacg gtcatacctt accgttattt ctttatcact agagtctgac gtaacttctt
    37201 gtgattcaac tgttggaata tctggatctt tgtacttgtc aatcttacca gatataacct
    37261 cgtcccagtt tcctgttgtc cattcaccgt aggttacaac tcccgtgacc ttgttctcag
    37321 tttttgtacg gcttaaggtt acaggttgaa caacatcttt ttttacattt tggttcgtaa
    37381 ctttatcaac gtaatgaatg atacgcgtta tagtcttcgt ctcagtagag gttgctgttt
    37441 tgggaaccac ttttcctcaa cattctcacg gtagtaatag tcaactgttg caccgtcttc
    37501 tggtacgcat ttgcaggagt tgctaccaag gtgtatgttg ttttccttgt gataactcgg
    37561 tcttctttgt cctcagttgt tgttttccct tcaatagttt ttgattctgt ggtatactca
    37621 gaacctatcg ctaaatcagc ttttataaca gactctgcca acttctcttg gctaccttct
    37681 ttatagtaat tggctgttac tgtagcagtg gttggcgctt cgctttctct ataaactaag
    37741 gtcactgttc tacctttgct tacaatattc ccagttaaac ttgcagaatt tgtatctact
    37801 tctttaaaag tataatattt tccgtcagta gtagtcatgc tactgagttt tttatctgtg
    37861 acattatagc tggtaccaat cagttgtttt ttattggtaa tgtaggttcc gtcactttct
    37921 ttttctccaa ttccagtatc atttttcaat gatagcaaac gcccttgttc atcaacatag
    37981 cgaactttca cattttctga gattagttct gccaattctg aggttttttt ctttttcttg
    38041 atttcttcgg ttattttccc tttctcttct tcgggaatat ttagttttgg aatgattttt
    38101 tcaacaacgg ttcgtgatgg ttccacagta tcttggatga ctgaaaagtc agctagaatt
    38161 gggagattat actgaacacg gtgactttga gtgtttactc ctactctttc attattctct
    38221 gaaaatactt gtacggtata agaaacaaca tcttttccta atagaacatc cccagtagag
    38281 aaatagccgc cttttcctag tttgctatct ccagagccca cttctttcct aatcttatca
    38341 gatagttttt taccagtcag tacattcgtt cgcacaatcc ctttgtctac ccctacaaag
    38401 tgggagaatt ttttgaactc ttcagaacca gatctagccc aaccattatt aagggcattt
    38461 gcttttgtat ttgtattctc tctcaaaggt ttggcgatta gaattatatt catcggcgct
    38521 tagagttgct gctatatctg actcttgaat accaacttcc ttactaccat ttctagcggc
    38581 agtatatgtg tatttatctg tttctacttc tagctgatta tccttaacat gataggtaat
    38641 tttctcctgg tataagagtc ttcagtagtt tatatgctct gtcatcatct ttagctttag
    38701 aagcagctga gtttagccaa gttggggtat taggagtatc tttatcagcc tgtttcaaga
    38761 cattattcaa gtcatttgct agcctattgg ttatcctcac tgtgaaagtt ttcttccagt
    38821 ctgaaccact tttattagac ttagatatgc tcatgaaatc ctggtcaaca ttcaacacaa
    38881 tatcgccttg ttttttagca tcttccgttg cttctgcttc aaattgatca tggagttttt
    38941 gttgctctgg tgtatagttt ttttatttac acgatttaat gtactatttt ttattttagt
    39001 attaagaact ccattaatac gatttttaaa ttctgcttca aaaaatccct taatttgttg
    39061 gtgcgcaagt tcaacattca aacctttctt atacaagtct tcattctgat acaagtcttc
    39121 attctgaacg atttcggcta cacggtgaat ggtttgattg tataccgtct tctcttaacc
    39181 agcagtatcc ttagttttaa tgactactcg ataggttcct ttagaaccgt tatagtcatc
    39241 tagttttaaa aaagcattcc aaacattcaa aaatagttgg aacttccctt aataaatccg
    39301 tcactttctt tttcaagata gcccaagctt gctcaatagg attcaaatcc ggtgaataag
    39361 gtggtagagg taagaaaaag tgtttatctt ggatgcagag ttcatccaaa atgttcttgg
    39421 gatgaaaact agcattgccc atgacaataa catgaggtgt cttcaaagca ggtaggagtt
    39481 gcgttttgaa ccactccaca aagaaatcgc ttgtcatgct tttcttgtaa atcatgggag
    39541 ctataaactc tccgtctact tgtcctgcaa caattgaagt tcgctcaaaa cgacgtccgc
    39601 taatcttttc atagactttc tcccctctag gagcccctgc ataaggacga tagaggtagc
    39661 ggtcgattcc tgtttcgtca atatatacga ttggtaaatc ttttaggtta tccaaaatat
    39721 caagaaactc agcgactttc tctggctctt gttccttaaa gctcgtcatc tttttttaaa
    39781 gtgaccttaa tctgctttaa agctgcccat actgaaggaa cagcacaatc aaaatgtgcc
    39841 gcaatttccc gtaaaaaagc atctggatga gcctctacaa aggttttcaa ttcctctaaa
    39901 ggaatctttc ggtttttgac gactcgcttt ttcctctcta tgtgttcttg ttcacatctt
    39961 tcttttccca cgtgaagaga gttctgacgc caacaccaaa aaacttggct gcctcgacat
    40021 ggctgtgccc ctctttgatg taatctaatg ctcgctgttt aaaatcagta ctatatgcca
    40081 tagctttatt ataatatgct tgtttaaaac taagcaacta tatcaatgtt ttgttatgag
    40141 aagacttact ttttttactg aaattgaatt tttcctagcc tcaacatcat ataaccccaa
    40201 aattcaatct gacctggttt gaagagatgt tcgaagcaga taaggtttta ctaaaactaa
    40261 aaaaaatgat ataatcaaac tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct
    40321 taccaagaaa attaccagaa atgggttgat tttgtggagc ttcctgacta ccttcgtcaa
    40381 gatttggaaa atatggacga aaaaactaag gaagatgcct tctatacaaa tcttgaattt
    40441 ggtactgcag gtatgcgtgg cttggttggt gctggtacaa accgtatcaa catctacgtt
    40501 gttcgccaag ctactgaagg attggctcgt ttgattgagt caaaaggtgg aaacgagaaa
    40561 gaacgcggtg tagcaattgc ctacgatagc cgtcacttct cacctgagtt tgcctttgaa
    40621 tctgcggcag ttcttgctaa acacggcatc aaatcttacg tatttgaaag ccttcgtccg
    40681 actccagaac tatcatttgc agttcgtcat ctcaactgtt tcgcaggtat catggtcaca
    40741 gccagccaca accctgctcc atttaacggt tacaaggttt acggtgaaga cggtggacaa
    40801 atgcctccac acgatgcgga cgctttgact acttatatcc gtgcaatcga aaacccattt
    40861 gcagttgaag ttgctgatgt ggaaactgaa aaagcttctg gcttgattga agttatcggc
    40921 gaagctgttg acatagaata ccttaaagag gttaaggaca taaacatcaa cccagccttg
    40981 attgaagaat ttggtaaaga catgaagatt gtctacacac cacttcatgg tactggtgaa
    41041 atgttggctc gtcgtgctct tgcccaagca ggatttgact ctgttcaagt tgttgaagcg
    41101 caagcaactg ctgacccaga cttctcaact gtaacatctc caaacccaga aagccaagca
    41161 gcctttgccc ttgctgaaga acttggtcgt caagttggtg cagatgttct tgtcgcaact
    41221 gacccagacg ctgaccgtgt tggtgttgaa gttcttcaaa aagatggtag ctacctcaac
    41281 ctttcaggta accaaatcgg tgctatcatg gctaaataca tcttggaagc tcacaaaaac
    41341 gctggaactc ttcctgaaaa tgccgctctc tgcaaatcta tcgtttcaac tgacttggta
    41401 acgaagattg ctgaaagcta cggcgcaact atgttcaacg tcttgacagg tttcaaattt
    41461 atcgctgaaa aaatccaaga attcgaagaa aaacacaacc acacttacat gatgggattt
    41521 gaagaaagct tcggttactt gattaaacca tttgtacgtg ataaagatgc catccaagcc
    41581 gttcttgtcg ttgctgaact tgctgcctac taccgttctc gtggtttgac acttgctgac
    41641 ggtatcgaag aaatctataa agaatatggc tactacgcag aaaaaacaat ctctgttact
    41701 ctttcaggtg tcgatggtgc tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat
    41761 gctccaacag aatggaacgc aacagctatc actgtcgtag aagacttcaa ggcacaaact
    41821 gctactgttg ctgacggtac tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa
    41881 tacacactta ctgacggttc atggattgcc gttcgccctt caggtacaga accaaaaatc
    41941 aagttctaca ttgcagttgt aggggaaacc aacgaagaat cacaagctaa gattactaac
    42001 atcgaagcag aaatcaatgc atttgtaaaa taaagaccta taaaagatga gaccaaccaa
    42061 cctcatcttt tttcgtatca aatctaagca attttagaaa ctttatggca tactagactt
    42121 atcaatgaaa gcgaggtaat ctcatggaac aatttttaga taacatcaaa gaccttgaag
    42181 tcactacagt tgtgcgtgcg caagaagctc ttgataaaaa agaaactgca accttcttta
    42241 tcggtcgcaa aacttgccct tactgccgta aatttgcagg tacattgtca ggtgtcgtag
    42301 ctgaaaccaa agctcacatt tacttcatca atagtgaaga accaagccaa ctcaatgatt
    42361 tgcaagcatt ccgctcacgc tatggaatcc caactgtacc aggttttgtt catattacag
    42421 atggacaaat caacgtccgt tgcgactctt caatgtcagc acaagaaatc aaagatttcg
    42481 caggattgta aaaaatcagc taacaagtct taaaatcaca aaaacgcata atgtaaggtg
    42541 caaaaacctt gatattatgc gttttattgt tcctaaaaca gttacatcag catttcatta
    42601 cagaacattt taattttgga agtcaaatca atttttaaca atgttttaga aatcacagtg
    42661 ggctattcca tattcaatta tccagattca atcgctatta tcgttttcct agattacaaa
    42721 aaaactacgt tttgctaatc aaaacgcagt ttcagccact attttatctt actgtccttc
    42781 ttttacttct ttggttgcta catcttctcc aaaccatttt tggctgattt cttggaactt
    42841 gccgtccttg taaagactag aaaaagcttc atttatcttc ttaaccaagt ttgtatcttc
    42901 cttacgggct ccaaccgcaa aagcttctgt ttctagtcca actgtaaaga cattataatc
    42961 gtttaaaaca ccttctgctt ctaaataata gtttgcatag acacggtcaa tcaatagacc
    43021 atcaattcga tcgtttttca aatcaatcaa ggcttcatta aaggtttggt attgattcgc
    43081 ttccttatta gcgacaatat tcttcaaaat ttctggattt gcttcaaagt ccgcataacc
    43141 agatgaacca gcttgagctc ctaatgtctt tccagtcata tcctttgcag tcgtgatacc
    43201 agatgatttc ttcgtaacca atacctgctc attcttcata tatgagttac tgaaagccac
    43261 cttttcacgg cgttcgtctg tagcggaata gccattccaa atcagatcaa tcgttccttt
    43321 tgtcaattca gcttctttca aatcccaatc aatcggttgc caatttaccg tgattccgta
    43381 tttttcaaaa acagctgtag ctaaatcaat atcaaatcct gcataagaac catctttctg
    43441 agcaaatccc attggaacaa aagtactatc aaatccaata gtaatagact tgttagactg
    43501 gtactttgac caattatctc cactagtttc gctagaattt ttcccacaag ctactaagaa
    43561 caaagcagtc atcagactga ctaatacaag catccatttt ttcatccatt tttcctccta
    43621 tttaggttct actttcaata atacatctgc gatattttca gcaaactgca aatcatgggt
    43681 aaccacaatc tgggtcatcc caagttccct attttgcaag attagcttct ccacttccaa
    43741 acgtaattct ggatccaggg cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat
    43801 catcatagca cgcgccaaag ccacccgctg cttttgccca ccagatagtg agaaaggata
    43861 ggcctctgcg tgtcctccta gtcctaactg ttccaagagt ccactcgcct tcttctcagc
    43921 ctcttcctgc ttcattccca tggtcttcac aggcgataaa gtcaaatttt ccagaactga
    43981 taaatgaggg aacagttgaa aatcttggaa tacaaatccc agtagattgc gcttctgcaa
    44041 ttcatccagc tctaaaggtt gtccattata aaagatttgc cctgaatcaa tggtttcaag
    44101 acctgcaagc atacgtaaaa gagttgtctt acctccacca gaaggtccaa cgatagccag
    44161 gatttgcttt tcaggaatac ttagactgaa attagacagg atttgtttgt ctccaaagac
    44221 tttattgata tttcgtaatt ctaacatggc agcctcctat ctataataac tatacttctt
    44281 ctcaactttt ttggaaataa ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc
    44341 caagaacata ggaactagac tagcatcgcg gttagcagct gttcgactag ccaagataag
    44401 gtctgaaatt ccgagagcat agaccaaaga agtatccttg accaaactca taacttcatt
    44461 aaagacacta ggaagaacga tcttggtcac ttggggcaag ataatatagc gcactctgtc
    44521 aaaagggcta aacttcaaga ccttggcggc ctcatactgt cctcttggaa tagtgtcaat
    44581 tcccccacgg aaaatttctg caaagtaagc tgcatagttg agaacaaagg caataatagc
    44641 tgcaggaagg cggtctaaac gaatcccaat acttgggagc acataataga taaaaatcag
    44701 ttgcaagagt aagggggttc ctcgcataac ccagatgtaa atgttaatca gataatggag
    44761 gggcttccaa tggacttgca aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag
    44821 caagaccagt gcaaagacct gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat
    44881 ctcaaataaa taagacatac tgcacctcct aaaagtaatt gttcctatta tagcatgaat
    44941 aaacaagatt accaagtatt tttgtaaaaa gattctacca tatacaaata aaaaccgtag
    45001 ctatcaaaag agataaacta cagttctata tgtttaaaca ttcttacaat ctctcaaaca
    45061 gttcttgcat ttgcacatca tctggaacca gttttaagta agtgtgagca tggacttttg
    45121 cttcttcaaa atgtcccaat tcacgcaaga gatagatata gtgttccaga aattctggat
    45181 tgtccttcaa atctcctgtc aactcttgat aatgctcata agcagtatcc aaatcgtcca
    45241 tttcttgata agaacgagca atcatccact tggtcaaaag attttctggc tcctcactct
    45301 gcaagtctag aatatcctca taacgctcct gctccagata aatagtggct aaacgaagca
    45361 agatttcttc tgtatcctca gcgtcttctt ttgcagcaag aagataattt tctgcaccac
    45421 tagcatcatg caattcataa gaaaattgtg aagcagctag caagaggcga gtttcaaagg
    45481 gatttttctc taatccttgc ttagcgatac gcagggcttc ttgaacttga tgttccttat
    45541 gtaaagcctg actgtaccca tactcatagc cttcaaagtc aggagaaatg gtatcaagct
    45601 gcttaaagta gagggtggct ttttgatatt cttcttgatc aaaataaaga tttgccaact
    45661 caaaagctgt taagtcatcg tattctaact ccagggcttt ttctaaaaac tcagtagccg
    45721 tttcaaattt ccctaactga gcataggcaa agccaattcg ttgataggtg gaaatgcccg
    45781 tttgctcata aatcgagcga ttatctaact gggcataggc ttgaatagcc gcttggtaat
    45841 tttccaactc actatccaac tctgccaaac ccaatatcaa gagagaatcc tctgagtagg
    45901 tcaaggcctc caataatttc tcacgtgcca catctgtcaa accttccagc tggtaaaggt
    45961 ctgccttcag agccaaagac gagacatacc agtcactgtc agcttggatt tcctcaagat
    46021 aggtaaaggc ttcttctatt tgaccatcct cgctagcaat tgcagctaga ttaagatgaa
    46081 cctctggaaa atcctctaca attttcaggt aaatttcctt ggcctgagga tagaaaccaa
    46141 tcccttcaag ataagttgcc aactcataca gaagatcact tgaatcattt tctaaagctt
    46201 tggcgaaata atgctcagcc ttagttaaat cttgctcctc caaagcctgt aacatctgtt
    46261 gactattgtt cactcttgac ttcctcaccc tctaattcat atagaccact gactacctta
    46321 taccattcga aaatggctga aatgacaacc ttagcagagg cataaaccgg aataccaagt
    46381 aaaactcccc agataccaaa catagatcct gaagttaaca aaacaaagag aacattaata
    46441 ggatggatgt ttaattgact tcccaaaatc aatggagaga caaaacggcc ttcaatagtt
    46501 tgttctacga taaagacaat cactactttc aaaagcatga ctggaccagc aatcaaaccc
    46561 aatactagag caggaagcat ggctagaaag ctaccaagat aagggaccag atttaaaata
    46621 ccagcagtaa cccccagcgt aaccgcatag cgtagaccaa taatcttgaa gaagatgata
    46681 aacattactg ctacaataat agccactgtc acttgccctc gaacatagtt ggacaactgt
    46741 tgattcacat ctgatagaac ttgtccaaca ggttccttca attttcttgg aatgaattgg
    46801 gtcaaatagt tacgcaagcc tttcccatca cgcaagagat aaaagagcat gaaaggaacg
    46861 ataatcaagg caacaatcac ttgagaagct ccgctaataa aggcactcac ccagttgact
    46921 gcctgagatg aaaccttact tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact
    46981 tgctctaatt gaggtctgaa atcatctggc aggtgctggg ctaccaatcc attaacaatc
    47041 ctatctatat cttctaagta aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc
    47101 agatttggaa tggcgactgc caagccccaa atgataaaga gagcgatgat aacaaagaca
    47161 atagtgatag ctataacacg attaacctta tgcttctcca tccaatcaac aataggattc
    47221 aacaaataat ataacaaacc agacaaaatg actggcaaca tcacaactgc caaaaagtct
    47281 aaaacaggtg aaaatagaaa actaatctta cttaaaataa aaagattcag tcccaataat
    47341 aaggttacta aaaataccgt aattgccttg ttatctaaaa accacttgaa aaaccaagat
    47401 aggctaaaat gtttctcttt ttgctccata aatacttcct ttctattgtt ctctcattat
    47461 accatttttg aaacaaaata actctttttt aaagtgctta catctaattg gatatcttta
    47521 atttacttgt ttttgtgata taatagtctt atctttacac agaggtatag taatgaaaga
    47581 aactgtttat tttggaactt atacacgtcg tacttctcaa gggatttaca aggcagactt
    47641 tgatacagaa actggtcagc tttcaaatct agaacttttt gcagctgagc cgagtccaac
    47701 ctaccttgcc tttgaccagc accaacattt atacactgtt ggtagccaag acgataaggg
    47761 gggaattgca gcctatcaaa ctgacgggac tgtgttaaat catgttgttg aagaaggagc
    47821 tccccactgt tatgttgctg tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca
    47881 caagggacaa gtccttgttt ataaacgcca ggaagatggt agtcttctac ttagtgatat
    47941 ggatcaacac agtggccaag gtccacatga aaatcaagct tccccccatg ttcactatac
    48001 agatttaaca cctgaccact atctagtgac ctgcgacttg ggaactgacc aagtcatcac
    48061 ctatgacctc gatcaagaag gaaaattatc taagctctat acctatcaca gcaagccagg
    48121 agcaggctca cgccatatca ttttccataa ccactataaa atcgcttatc tcatttgtga
    48181 actcaatagt actatcgaag ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca
    48241 ggttatttca actttaccag aagcttacga aggctttaat ggaaccgctg ctattcatct
    48301 ctctaaagac ggtaaatacc tctacgcttc taaccgtggc catgattcta tcgcagtata
    48361 taccatcctt gcggacggta gcttagagtt attagaaatc gttccaacgc atggtcagac
    48421 tccacgtgat tttgatttga cacccgacca aaaatttctc attgttgtcc atcaagactc
    48481 tgacaatgca actgtcttta aacgtaattg tgacaatggt cgtctagcag aactctccaa
    48541 cgacttccat gttcccgaag cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa
    48601 tgaacttggt attttcaagt tcattttttc ttatagtcta tttccgacat taatacggtt
    48661 aatggcacgt tgcaaagcaa tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg
    48721 tgcttcttca attgcacgtt ctgcacgaag tttggcacgt tctgcacggc taatatcgat
    48781 atcacgagca cgttctgcag agtcagcgac gattgtgatc atatcattgg caatttcaat
    48841 aacgccaccg tttactgcaa tccagttcac gtgatcttta tcatcgatac gttttacctt
    48901 tacttcatca actgctaaaa ccgcaatcat attttcatgt cgtggcaaga tccccatctc
    48961 accatccaga gttcgaaccg atacatagct ggcatggtga tcatagacga gaccatctgg
    49021 tgtcacgatc tggacagtta actgagccat aggtcacctc ttaaaatccc attttttcag
    49081 cttttgcaat cacatcttcg atagaaccta caccacggaa ggcatcttct ggcaagtggt
    49141 cgtatttacc atcaaggatt tccttaaagc cacgtacagt ttcagcaact ggaacataag
    49201 aacctggctg accagtaaat tgttccgcaa cgttgaagtt ttgtgacaag aagaactgga
    49261 tacgacgggc gcgagcaacc aaggtctttt cttcatcaga aagctcatcc ataccaagga
    49321 tagcaatgat atcttgcaat tcatggtaac gttgaaggac acgttttact tcagcagcaa
    49381 ctgcatagtg ctcttctcca acgatttcag gtgccaaggc acgtgagctt gaagcaagtg
    49441 ggtcaacggc tgggtagata cccaattgta ccaatttacg ttccaagttt gttgttgaat
    49501 ccaagtgagc gaaggctgtt gctggcgctg ggtcagtata gtcatccgct ggcacataga
    49561 tagcctggat agaggttaca gaacccttct tggttgatgt gatacgttct tgcaattgac
    49621 ccatttccgt agcaagtgtt ggttggtaac caacggctga tggcatacga cccaaaaggg
    49681 cagatacttc tgaaccagcc tgagtgaaac ggaagatatt atcgataaag agaagcacgt
    49741 cttggccttc cacatcacgg aagtattcag cgattgtcaa accagtaagg gcaacacgca
    49801 tacgtgctcc tggtggctca ttcatctgac caaagaccat ggctgttttc tcgataacgc
    49861 ctgattcttt catttcccag taaaggtcat tcccctcacg agtacgttcc ccaacaccag
    49921 taaatactga aataccaccg tgctcttggg caatgttgtg aatcaattct tggattaaga
    49981 cggttttacc aactccggca ccaccgaaaa gtccaacttt accaccttta aggtaagggg
    50041 caagaaggtc aataaccttg atccctgttt caaggatttc agaagaggta gacaactcat
    50101 caaaagttgg agctttttta tgaattggct gacgctctgc gtcttctgta aaaggagctt
    50161 ccaaatcaat ggtatctccc aaaacgttga agacacgtcc caaagtttct ttacctactg
    50221 gtacagagat tggacgacct gtgtccaata cttccattcc acgagtcaac ccatctgttg
    50281 attccatggc gatagtacga accataccat ctcctaactc caaggctact tcaaggacga
    50341 tttttgtttt tctttcgtca tttttgtaga cgacaagtgc attgttaatc tcaggaagtt
    50401 tttcccctgc tgcaaacaaa acgtctacaa cgggaccgat aacctgagca attttacctg
    50461 aactcatctc cttctcctat tctatataag atactgtcgg ttcctagctc aactaggtcc
    50521 taagttcatt ttcatacgag ctggactaga gcctattcta aggcactagc acctgctacg
    50581 atttctgtaa tttcttgtgt aatcgccgcc tgtctggcac ggttatactg aattgtcaaa
    50641 tcattgatga ctttcttagc attatctgtc gctgtttgca tggctgtcat acccgcagca
    50701 ttctcagctg tcttggcatc gataatggca ccgtaaatca tactttctgc aaactgaggc
    50761 aacaactgct ccagaatttc ttctcggctg gtttccaatt caaaagtcaa gctgtactct
    50821 tcatccgctt catttggatc caagtcaaca atcggaagca tttgttccac acgcatttga
    50881 ctggttagcg tattgacatg gtggttgtag caaacataaa gctcatcaaa gagttcattt
    50941 tggtacattt caacagtttt tgaaataatc ttacgaactt gatcaaagct aggttggtct
    51001 gccaagccac gtaattcata aagtggttga ataccgcgag ccttaaagaa atcagctccc
    51061 atcccaccga tacagatcat ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac
    51121 tccataacag ctttcaaaat agaggaatta taacctccaa ccaaaccgcg gtctgaagtg
    51181 ataacgatat agcctgtctt cttcacagaa cgactaatca acatcggatt agttgaagca
    51241 ccagctccat taccatgaag gatatctgtc aaaagtttac gcactttctg agcgtaaact
    51301 tggaagttgc gagcagcttc ttcagagcga cctagcttag cagccgatac catttgcatg
    51361 gcattagtga tttgactcgt attttttgtt gaggcgattt ttgttttaat atcatttaga
    51421 gacactgcca tctgacacct ctattcttat tggaagctag attgattgag aaactctgta
    51481 atcgcagcat ccaagactgc ttcttctggc aagtcttttg tatcacgaat ggtttccaaa
    51541 atctctggat gttgagcatc aaagaaggca tggaactctt cctcgaaacg aacaatatca
    51601 tctactggaa cagtatccaa gaaaccatgt gtcaaagcat aaagaatggt tacttgtttc
    51661 tcaacaggta atggtttgtg aacaggttgt ttcaagacct caacggtacg acgtccacgg
    51721 ttcaacttag cctgtgttgc tgcgtccaag tcagaaccaa acttagtaaa ggcttctaac
    51781 tcacggtatg aagcaaggtc gatacgaagt gtaccagcaa ccttcttcat ggctttgatt
    51841 tgtgcagaac cacctacacg agatacagat gaacccgcat cgatggctgg acgaatacct
    51901 gcattgaaga ggccatcgcc aaggaagatt tgtccatcag tgatagaaat cacgttggtt
    51961 gcgatatagg ctgagatatc tcctgcttgt gtctcgataa atggtagggc tgtaattgat
    52021 ccaccaccaa gttcatcaga aactttagct gagcgctcaa gcaaacggct gtggagatag
    52081 aaaacatccc ctgggaaggc ttcacgacct ggaggacgac gaagcaagag cgatagttca
    52141 cgataagcta ccgcttgttt tgatagatca tcgtatacaa tcaaaacatg cttaccttga
    52201 tacataaatt cttccgccat agcaacccca gtataaggag ctaggaagag caatggagat
    52261 ggttgtgaag cagaggctgt cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt
    52321 gtttctactt gcgtacgaac tgttgattct ttttgtccaa tcgcgacgta gatacagatc
    52381 atatcttgat ctttttggtt caagattgta tcaatcgcaa tggttgtttt ccctgtctga
    52441 cggtcaccga taatcaactc acgttgacca cgaccaatcg gtacaagggc gtcaatagct
    52501 ttcaaaccag tttgcaatgg ttctgaaaca gacttacgtt gcataacacc aggagctggt
    52561 gcttctactg gacgagtttt atcagtgtgg atttctccaa gaccgtcaac tggacgacca
    52621 agcggatcca caacacgacc aatcagactt tcacctacag ggacttccat gattttccct
    52681 gtacggcgga ttgtatcgcc ttcacggata tctgtaaagt cacctaggat gataatacca
    52741 acgtctgttg actccaagtt ttgagccata ccataagagc cgttttcaaa attcaacaac
    52801 tctccactca tgacattttc aaggccatga gcacgcgcga taccgtcccc gatataggtt
    52861 acaacacctg tttcagtcac atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt
    52921 aaagcgctga tttcttgtgc gttaattgcc aaaagaacac cactttctat ttcaaatttt
    52981 ctttaacaac tttaagttgt tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa
    53041 tgacaaaacc accaatgaga ctttcatcga tttgttcttt tacactcctt actttcagag
    53101 acattttttt ctcaatcaaa gggagcaaac gagtcttctg ttcatcagtt agaggatgag
    53161 cagacgtaat cgtcacttca aatcgatttg tttctttttc aagtcggttc aagcaatcta
    53221 caagcacatc ataaaaaaga tttgctctgt gattgtaggc cagaacctgg ataaagtttt
    53281 gtaataaagg cgacacagaa tcttggaaaa aagcaattgt tttttcctta tccgactcgt
    53341 ctactgccac ttgttttaaa aaagaaggca gacctgtttt ttcaacaact tgcttgattt
    53401 gagtcaagtc tgaaaagata cggtcttctt ctcctttttc aagtaccaat tggacaaaag
    53461 gcatgctgta tttttcaatt acctttactg ttttcttgtc cattaagctt ctcctagctg
    53521 atcgatatac tgatcaatga gtgctttatg ggcatgactg tcaaggtttt gtgagatgat
    53581 tttaccagct aagctgatgg tcaaatctgc gacctcaccc ttaacactct gtaaagcttc
    53641 tactttattt tgagcaattt cttgattggc tttttctttt aagtgtcctg cttctagttt
    53701 agcatctgct aagatattag ccttactttg ctcagctgtt tcctttgcat tttcaatgat
    53761 tgtcttagct tctttacggc taccagccaa ttcatcttcg cgtttttgag ccaatacttc
    53821 tgctttttga cgggcttctt cagctctgtc aatatctgaa gcaatttttt cagctctttc
    53881 ttcgaaaatg cctgtaatat tagaccatgc aaatttttta atcaagacta gcaaaagaat
    53941 aaaagagcca gtgattaaaa taaaattacc aattaattca cctactgtta cgtgcatcag
    54001 ttactccttt ctattcctct tcaatattaa tcttattccc taaatacaca gatgtcaaaa
    54061 gagtaaaaac ataagcttgg atgcaggaaa taaagacaga aaatgcagtc caagccaaat
    54121 tagctccaaa ggctactgga taccaataaa tagcttggtg ggaaagaaga agtaacaaac
    54181 tcgtcatgac ctctcctgca aagatattcc caaaaatccg caaagccaaa gataagaagt
    54241 ttgtaaattc ttccaagata ttcatcggta tgacaaaaac aggactcata aaagatttta
    54301 tacttttttt aaatccacga cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa
    54361 aagataaggt taagtcatac tgtaaattag cggttggcga actccaccag ttagtcccat
    54421 cgatcgtttg aatctttgtc attaagccaa ggttattggc aatcaccatg aaaaggaata
    54481 aacaaaggaa aaagagtgag taatctttca tgtagcgcga accaatgtta ggttctgtaa
    54541 atccaataac aaagtcatag acatactcaa gtacattttg ctttcctttg ggtttcaagg
    54601 tcatattgcg gcttgcccaa taaataaaga caaaaataac tcccacaatc aacaaagtca
    54661 tggctaacat agtcagattg aagataacag gaccaataga gatgattgga ttaatacttt
    54721 cttccatcta aaatcctccc ttttcttctc gttccatgta tttatttgat aataaatgag
    54781 aagacaagag ttacaaagaa agttccttca ataaaggcaa cacctaaaaa catcaaacta
    54841 cgaaactcag aaagcatatc tggttggcgt gctactgatt taaacagtcc attcatcaat
    54901 aaaccttcac cgacagatac gcccatacag gcaatacata agcctaaaaa tgttaaattc
    54961 ataacaaatt ctcctttaaa ataaaattta cttacttagt gtagtcctaa aatttaaatt
    55021 tgtcaacttt taaccgctat tggaagcgtt taataaaaat tatttccatt ttgctaaatt
    55081 tcaa
//
LOCUS       DBEROT010000009        49835 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.09, whole genome shotgun sequence.
ACCESSION   DBEROT010000009 DBEROT010000000
VERSION     DBEROT010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 49835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.09"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(12..308)
                     /locus_tag="ACL8CG_000644"
     CDS             complement(12..308)
                     /locus_tag="ACL8CG_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343287.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(292..2451)
                     /gene="pfbA"
                     /locus_tag="ACL8CG_000645"
     CDS             complement(292..2451)
                     /gene="pfbA"
                     /locus_tag="ACL8CG_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGS1343288.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYNIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3581..4807)
                     /locus_tag="ACL8CG_000646"
     CDS             complement(3581..4807)
                     /locus_tag="ACL8CG_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGS1343289.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4850..5542)
                     /locus_tag="ACL8CG_000647"
     CDS             complement(4850..5542)
                     /locus_tag="ACL8CG_000647"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS1343290.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNCRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5715..7466)
                     /locus_tag="ACL8CG_000648"
     CDS             complement(5715..7466)
                     /locus_tag="ACL8CG_000648"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343291.1"
                     /translation="MQNKQEQWAVLKRLMSYLKSYGLLIFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKVLILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(7456..9201)
                     /locus_tag="ACL8CG_000649"
     CDS             complement(7456..9201)
                     /locus_tag="ACL8CG_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HGS1343292.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9407..9784)
                     /locus_tag="ACL8CG_000650"
     CDS             complement(9407..9784)
                     /locus_tag="ACL8CG_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGS1343293.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9856..10312)
                     /locus_tag="ACL8CG_000651"
                     /pseudo
     CDS             complement(9856..10312)
                     /locus_tag="ACL8CG_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10446..11273
                     /locus_tag="ACL8CG_000652"
     CDS             10446..11273
                     /locus_tag="ACL8CG_000652"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGS1343294.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11285..11380
                     /locus_tag="ACL8CG_000653"
                     /pseudo
     CDS             11285..11380
                     /locus_tag="ACL8CG_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
     gene            11428..11667
                     /locus_tag="ACL8CG_000654"
     CDS             11428..11667
                     /locus_tag="ACL8CG_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGS1343295.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12050..12145
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12545..13126
                     /locus_tag="ACL8CG_000655"
     CDS             12545..13126
                     /locus_tag="ACL8CG_000655"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGS1343296.1"
                     /translation="MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVLFKEADL"
     gene            13126..14388
                     /locus_tag="ACL8CG_000656"
     CDS             13126..14388
                     /locus_tag="ACL8CG_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGS1343297.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIFVASLLAIVLNAVLNHKKK"
     gene            complement(14439..14900)
                     /locus_tag="ACL8CG_000657"
     CDS             complement(14439..14900)
                     /locus_tag="ACL8CG_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGS1343298.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14897..15661)
                     /locus_tag="ACL8CG_000658"
     CDS             complement(14897..15661)
                     /locus_tag="ACL8CG_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnI domain-containing protein"
                     /protein_id="HGS1343299.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQYG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15842..16246)
                     /locus_tag="ACL8CG_000659"
     CDS             complement(15842..16246)
                     /locus_tag="ACL8CG_000659"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGS1343300.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(16316..17797)
                     /locus_tag="ACL8CG_000660"
     CDS             complement(16316..17797)
                     /locus_tag="ACL8CG_000660"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS1343301.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKAQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            complement(17816..18994)
                     /locus_tag="ACL8CG_000661"
     CDS             complement(17816..18994)
                     /locus_tag="ACL8CG_000661"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGS1343302.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19158..20165
                     /gene="galR"
                     /locus_tag="ACL8CG_000662"
     CDS             19158..20165
                     /gene="galR"
                     /locus_tag="ACL8CG_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGS1343303.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20211..21248)
                     /locus_tag="ACL8CG_000663"
     CDS             complement(20211..21248)
                     /locus_tag="ACL8CG_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGS1343304.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21249..21602)
                     /gene="nmlR"
                     /locus_tag="ACL8CG_000664"
     CDS             complement(21249..21602)
                     /gene="nmlR"
                     /locus_tag="ACL8CG_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGS1343305.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21846..22736)
                     /gene="czcD"
                     /locus_tag="ACL8CG_000665"
     CDS             complement(21846..22736)
                     /gene="czcD"
                     /locus_tag="ACL8CG_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGS1343306.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22869..23405
                     /gene="sczA"
                     /locus_tag="ACL8CG_000666"
     CDS             22869..23405
                     /gene="sczA"
                     /locus_tag="ACL8CG_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGS1343307.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            complement(23571..24377)
                     /gene="pnuC"
                     /locus_tag="ACL8CG_000667"
     CDS             complement(23571..24377)
                     /gene="pnuC"
                     /locus_tag="ACL8CG_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGS1343308.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24722..26242)
                     /locus_tag="ACL8CG_000668"
     CDS             complement(24722..26242)
                     /locus_tag="ACL8CG_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGS1343309.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26235..26963)
                     /locus_tag="ACL8CG_000669"
     CDS             complement(26235..26963)
                     /locus_tag="ACL8CG_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1343310.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(26978..27742)
                     /locus_tag="ACL8CG_000670"
     CDS             complement(26978..27742)
                     /locus_tag="ACL8CG_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGS1343311.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27746..28189)
                     /locus_tag="ACL8CG_000671"
     CDS             complement(27746..28189)
                     /locus_tag="ACL8CG_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS1343312.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            complement(28871..29167)
                     /locus_tag="ACL8CG_000672"
     CDS             complement(28871..29167)
                     /locus_tag="ACL8CG_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS1343313.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            complement(29189..30253)
                     /gene="pepA"
                     /locus_tag="ACL8CG_000673"
     CDS             complement(29189..30253)
                     /gene="pepA"
                     /locus_tag="ACL8CG_000673"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGS1343314.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30654..31355
                     /gene="galE"
                     /locus_tag="ACL8CG_000674"
     CDS             30654..31355
                     /gene="galE"
                     /locus_tag="ACL8CG_000674"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS1343315.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31371..31481
                     /locus_tag="ACL8CG_000675"
     CDS             31371..31481
                     /locus_tag="ACL8CG_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGS1343316.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            31778..32737
                     /locus_tag="ACL8CG_000676"
     CDS             31778..32737
                     /locus_tag="ACL8CG_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1343317.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSILFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32727..33683
                     /locus_tag="ACL8CG_000677"
     CDS             32727..33683
                     /locus_tag="ACL8CG_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGS1343318.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            33680..34432
                     /locus_tag="ACL8CG_000678"
     CDS             33680..34432
                     /locus_tag="ACL8CG_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343319.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            34528..35493
                     /locus_tag="ACL8CG_000679"
     CDS             34528..35493
                     /locus_tag="ACL8CG_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1343320.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQKVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35718..35960)
                     /gene="yidD"
                     /locus_tag="ACL8CG_000680"
     CDS             complement(35718..35960)
                     /gene="yidD"
                     /locus_tag="ACL8CG_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGS1343321.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(35960..36682)
                     /locus_tag="ACL8CG_000681"
     CDS             complement(35960..36682)
                     /locus_tag="ACL8CG_000681"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS1343322.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36669..37238)
                     /gene="scpB"
                     /locus_tag="ACL8CG_000682"
     CDS             complement(36669..37238)
                     /gene="scpB"
                     /locus_tag="ACL8CG_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGS1343323.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37257..37985)
                     /locus_tag="ACL8CG_000683"
     CDS             complement(37257..37985)
                     /locus_tag="ACL8CG_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGS1343324.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37985..38719)
                     /gene="xerD"
                     /locus_tag="ACL8CG_000684"
     CDS             complement(37985..38719)
                     /gene="xerD"
                     /locus_tag="ACL8CG_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGS1343325.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38716..39177)
                     /gene="cbpB"
                     /locus_tag="ACL8CG_000685"
     CDS             complement(38716..39177)
                     /gene="cbpB"
                     /locus_tag="ACL8CG_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGS1343326.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39174..39695)
                     /locus_tag="ACL8CG_000686"
     CDS             complement(39174..39695)
                     /locus_tag="ACL8CG_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS1343327.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39671..40642)
                     /locus_tag="ACL8CG_000687"
     CDS             complement(39671..40642)
                     /locus_tag="ACL8CG_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGS1343328.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40639..41433)
                     /gene="racE"
                     /locus_tag="ACL8CG_000688"
     CDS             complement(40639..41433)
                     /gene="racE"
                     /locus_tag="ACL8CG_000688"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGS1343329.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41640..41888)
                     /locus_tag="ACL8CG_000689"
     CDS             complement(41640..41888)
                     /locus_tag="ACL8CG_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGS1343330.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42030..43655)
                     /gene="treC"
                     /locus_tag="ACL8CG_000690"
     CDS             complement(42030..43655)
                     /gene="treC"
                     /locus_tag="ACL8CG_000690"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGS1343331.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43833..45800)
                     /gene="treP"
                     /locus_tag="ACL8CG_000691"
     CDS             complement(43833..45800)
                     /gene="treP"
                     /locus_tag="ACL8CG_000691"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGS1343332.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QCVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            45985..46695
                     /gene="treR"
                     /locus_tag="ACL8CG_000692"
     CDS             45985..46695
                     /gene="treR"
                     /locus_tag="ACL8CG_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGS1343333.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(46728..47531)
                     /locus_tag="ACL8CG_000693"
     CDS             complement(46728..47531)
                     /locus_tag="ACL8CG_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343334.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGRN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(47544..48421)
                     /locus_tag="ACL8CG_000694"
                     /pseudo
     CDS             complement(47544..48421)
                     /locus_tag="ACL8CG_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(48433..49370)
                     /locus_tag="ACL8CG_000695"
                     /pseudo
     CDS             complement(48433..49370)
                     /locus_tag="ACL8CG_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        14563 a        11400 c         9256 g        14616 t
ORIGIN      
        1 ttgtcctatt attatttcat tttactatac tctgttaatt catatgagtt taaaccgatt
       61 tcatctttaa cctcgagtaa agcagtttca aatatttgtt taagagtttt tgattcttta
      121 caattaaccg acaaactttc tgataaaata tgtacaactt ctgagactga ataacctatc
      181 tcctctttag aattatataa atctgtagct ccaccaataa tccaaaaata ctgattttgt
      241 gaacctacaa tatcctcatt ttctacggaa cttccttgta tcgaacaaat tttatttatc
      301 tttaccataa tacttcaacc cttttagtgt caaaagtaaa ccaattcctg tcactgttaa
      361 gaatagttcc ataatcttgt tcgaaccagt ctttggtaat ttttgtttta catctactat
      421 ttctttagat ttattaatat gattttcagt ttctctgcca tctccaacta ttttatagtt
      481 tacttcttct gtcttattat cttgtttatt gtcgatcttg tcattcattt gtctattatc
      541 tttacttgag ttaaactctc cgttcttctg gttactatca attacattat ttgaattaga
      601 ttgtttttcc tctttgtttt tttctttttc gtttttatca cttaaattat ttgttacaat
      661 attgtaaagc ccattctccg ttacaatatt gaaattacca tcgctatcac gtataacagg
      721 ttctttccca tttgcattag atttgatgaa tgatatatac ttaccggata aattataaaa
      781 ttggttattt aaaacggtta ttttaccctt tgaatcctca ataacaattc cttctttacc
      841 cccgaatata ctattctctg agactactaa attatcacta actcgtaata attcaatatt
      901 tggttgttct gtttccttag aattattatt aattacattt tttgttacag taatatctga
      961 tacttttcct aaatattctg cactatcttt tgcaactcgt atcgcttttg ttttaggatc
     1021 ggcaatatta aatatatttt cggcgataac cacctgttta tttaaatcta ataggtcttt
     1081 agtgttttta tagctataag catttactaa agctgctccg ctttctcgat aatgtacact
     1141 ctctccttta actttcttat caaagcgatt tcctttgatt aatacatcag tgaatcctgt
     1201 aaaacgtaca cctgcataca tcatgttatc aaaatgatta tttaaaattt taatattaga
     1261 ggggttctgt gtcgacaatg tttgatagtg tgtgccaatt gctgttacta attccccaga
     1321 tttatcactt ttgccaaaat aggaattttg aatagtcaca ttttcagatt ttttcccatc
     1381 atcattcaag gcataaggaa aaccttttct agttaatggt tcaatctgaa tgctctcctt
     1441 acttatgatt tgcccatcct tcatcgtttt gggtaaggct tgcccaagaa aacgagaatt
     1501 atcaactaat acatttttcg aacctgcaat ttgaatagca tgcccttgat aactatcctt
     1561 gaatgttaca ttttttatag ttacgttatt tgaattccca atagcaaatg cacctgaaga
     1621 atttataagt ggtagatttt ttgctttagt tccttcttca ttcaaagcac cgttcatatc
     1681 aatcgtacca ccagaataac taatatcttc tgttgggccc cattctactt gcgcaccatc
     1741 atccgtaaat aaacctgtca taaaaacaat ggaagggtga ttcttaatat ttataccatt
     1801 tagaattgta gctttctcat tcaattctaa gtgtgtatga ctttttaaaa aaacaatttc
     1861 ttttactaaa taagttcctt caggaaaata tacatttcct ccacctagcc cttgagctgc
     1921 agcatctatt gcatcttgaa ttgcttgtcg atcatcatga atcccatcac ctaccgcacc
     1981 ataatctttt acacttaaag cagtatcttc aaattctttt ttgataattc tgtcacttat
     2041 aacatcttcc ttataactct tattttcatt agtagatgtt actgtagatt caactgttct
     2101 gttgtctaat tgtgaattgg aacgaatagt accattagag ctgatactat taacacttaa
     2161 cgaattatct aaaccattag tggttgaatt agaggcaatc atttcagcag aacgattctg
     2221 attaacagtt ggtgaattat ctaaatcatt agtaattgca ttagaagact cttttgtagc
     2281 catcggtgaa gaactagtaa caacttcatc cgataaaata ccttggcttc ccaaaattga
     2341 aattgccaat agtaccgagc aagtccccac ctttaattta cgaatactga atacctcatt
     2401 aggaacaaaa tatttcatca gaacctccaa tttttttact atttttaaca attgattatt
     2461 acttttctta aaatagatag aatgacaccg ctgtcattat ctttatcata tattttccaa
     2521 attgaattgt caaggaataa cacaagaaaa tattaaaatt tatactcttc ggaaatctct
     2581 tcaaactagg tcagtgccgc cttgccctaa gtctaggtta ctgacttggt cagttctata
     2641 gtagactgaa actaaaatag tacacctcta cttctaaaac attgttagaa atcgatttga
     2701 ctgtcccgat caatttgtcc tattcttatt tcattttact atatctacaa cctcaaagca
     2761 gggttttgag ctatctatgg ccaacttcct agtttgctct ttagccttcc attcaaaagt
     2821 gatgctatct ttcttagctt gaatataaaa tatcccattt actatattta aatttgttga
     2881 tatgttgtaa attataaatg aaagaacaaa taccttgtca tacaagcatt cgccagggat
     2941 atttacctga atatcgctca tatggcggat tgaaactaaa acactacaat atatttctta
     3001 aatagacctt ctataaaagc tagatttaac ctcgataaaa atagatgcag tgcttctaaa
     3061 atactggaat agggcatata ggtaatcgta gacaagtgtt ttatagattg tctcgcagga
     3121 gatctaatga tgtatagcaa gcatcactaa acatatagaa tatttgtatt attataatat
     3181 caacatgcta taaattctat catgcaaaag aatgactaga acatgaaaga caggcacaaa
     3241 attttgaaca atattctgaa aacaaaaaaa gacgcgagtt tccacaatct cactcatgga
     3301 aactcacgtc tttcaaaaaa tagggtgaat tgaaaactag aacaagacac tagattttct
     3361 aaatgatgtc tagtaaggat tctaaatgct acactaaatt gctcacatct tatttcaaac
     3421 cacgggactc ccacaagaaa ggaaaatcct ataaaaattc tctctctgag gagaaagagg
     3481 cctcaactac aggtgtaaac tattatcaat tgaaaacaac agtttttaca ctcaattaga
     3541 ctttttaggg acaggatcac tttcgcttga ctgtagtttg tcattttttt gataaagtta
     3601 gcactttttc agaaactgtt ttgaaagtct caatgatata gtctacttct tcatcgctta
     3661 atttagtatg aagagggagg gtaatttcat tctcaaagaa ggcataggcc ttaggatagt
     3721 tcgtcatatc aaatccaaga ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa
     3781 cattacttgc aattcctgct ttagccaatt cttggatgat gaggttgcgt tcttctaggc
     3841 ttgctccttc tacacgggtg atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt
     3901 gtgccaaagg atggatgcga gaacctgcaa aaccactatc atagcggtcc acaatgtcct
     3961 tacggcgttg caacaaactt ggatagcggt ccaattgtac caaaccaagt gaagccatga
     4021 tatcggtcat gttgcactta taggctggtg taacgatatc gtattcccat gaccccaatt
     4081 gcatcttggc aagagcatcc ttagtttgcc cgtgaaggga aaggatttgg aattccttgt
     4141 acatctcttc gtcatcaatc actggattgg ctttccaagt cgcacttcca ccttctgccg
     4201 ttgtaaagtt cttaacggca tggaatgaga aggaagtaaa gtcagcgata gaaccagaag
     4261 gttgtccttt ataagtagat cccaaagcgt gggcactatc agagacaatg acaatacggt
     4321 taaaggcctt ttgccacttg cttgaagcgg taaagaagtc acgttttttc tccacgactt
     4381 ggaacaaacg gtcataatcg caaacaatcc ctgcgagctc tactgggata atcaccttag
     4441 ttttctcagt gatagcttgc tcaagcaggt catagtccat ctcaaacgta tctgcttgga
     4501 tatccaccat gacaggggtt gctcccacgt gcgtaatgac actacatgaa gccgtatagg
     4561 tcatggctgg aacgatgact tcatcaccag gtcccacttc caaaacgcgt aaaatcaact
     4621 ccagagcggc tgtcgcagag ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca
     4681 agcggcgctc cagttctttt gttttaggac ctgttgtgat ccaaccagaa cgcagggtat
     4741 ccgctacttc agcaatttct gcttctgtga tatcaggcgg tgaaaatgga atattgtaat
     4801 ttggcattga tttgctcctt ttatctgtac tcattttctt atgactactt tattttagta
     4861 cctcaaacac ggtttgaaac atgattttga tgtccccaaa gaaactaaac tctcggagat
     4921 aggcgaggtt atagcgcatc ttttcaggaa gaacatgctc cacataggcc tgatcaactg
     4981 acagaccttt ctccgtcatt tgactgatga tggtgtcctc atccttgtag ttgatgctgg
     5041 ctggagaggt aattcctgct tgcaagagca aggttgccat catttcaggg ctatactgct
     5101 ctgtataacg tggcacttca ggtcgtgtac cgacaaagga catctcacct ttaaggacat
     5161 tgaccaactg aggcagttcg tccaaacgga cacgtcggat gaaatttcca accttggtaa
     5221 tacggctatc gttagcagaa gtcaccagac ttcctttttt atccgcatcc gtcaccatgg
     5281 tacggaactt ccaaatcttg aaccgacagt tgtactgggt cacacgctct tgcttgtaaa
     5341 tcactggccc cttgctatcc aacttgatcc aaatgctcaa gatgagaaag atgggagaag
     5401 ttagaaccag taagaccaag gccaaaaccc agtccaagca acgcttgaaa atcagcgaac
     5461 ccttcctttt agagacaagc tggtagtaag actcaacctc gcttgatttc atttccacag
     5521 gcaagtcttc ccatttcagc atgctgttct cctttgtttt tattatacta tttgtcaaca
     5581 tttttcatta taccacaaaa tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt
     5641 ccttctagta ctcaatgaaa atcaaagtac agctttgaga ttgcagataa agctgacatg
     5701 gtttaaagag attttcaaag agtatcggcc atggcccctg cctgcaaact atacatcttg
     5761 tgataagttc ctcccagagc caagagttcc tcatgggttc cactctcgat aatgcgtccc
     5821 ttatccaaga catagatgca gttggcgtct tgaatagtag aaaggcggtg agcgatagca
     5881 atagttgttc ggccctgtct catcttcgcc agagaagctt gaaccaagct ttctgtttca
     5941 gagtcaatat tggctgtcgc ttcatccaaa atcaggactt taggctggct ggcgactgtt
     6001 ctagcaaagg caagaagctg gcgctgccca gtagagaagc tcgaaccacg ctcggaaaca
     6061 ggggagtcgt acccctgagg aagttcttga ataaaggaat ctgcatccac aaaggctgcc
     6121 gcagcctgaa cctgctcatc actgatttct tggtacatgg caatattgga cttaatagtt
     6181 ccatgataga ggaagggttc ctgcaagacc aaaccgatgt tttttctcag ctcttcttga
     6241 ctgaaatccc tgatatccac atcatccaag agaactctcc ctgactggaa ttcataaaag
     6301 cgcatgagga cattgataat agacgatttc cctgaacctg tatgacctac aaaggcaatg
     6361 gtttcaccct tattaacaga gaaagaaatg tcatccagaa tcggatgttt accgtcatat
     6421 gagaaacaca catgttcaaa acggatattg ccttcttgga ctttggcttg cccattttct
     6481 tgaagaggtt cataggtcct ctcgtctatc agggcaaaga cacgacctgc agaaaccata
     6541 gccgtttgca gagttgaaaa gttttgcgtc acctcaatca aggggtcaaa aaggcggttg
     6601 atgtactgga taaaggcata catggtcccg accgttatcc cgatagaaaa accacggtag
     6661 ccaaagtagg ccatcaagac tgcatagcct agaagtttca gcaaactcat ggcaggtctc
     6721 aaaaagaggg catccaaggc tacagaacgg ttggcgtaga ccaagtgttc ttggttgatt
     6781 tcatcaaatt ctgcctgcag gcgcttctct tgattaaaag cctgaataat cctgattccc
     6841 tcgatattct ctgccagctt actattgata tctgacaaga gacttctggt tttctcgatg
     6901 attttcactg acttttttcg atagagattg accaaaagga aaatcaaagg aagaaagagc
     6961 aagactaaag ccgtcaaacg aaaatccagc accaacatgg tataaagggt tgtcagaaag
     7021 ataaaaactg ctgagataaa gctggataaa atcccagaaa acatatcact aatcgtctcg
     7081 gtatcgttgg tcaaacgaga aacgatagaa cctgctggcg tcttgtcaaa gtaagacatg
     7141 cccagtttct ccatattggc aaaggcatcc cgacgaatat ccctaacaat actgtaagac
     7201 acgcgcgcaa agagaagatt gcctacatac tgaactacag tttgtaggat gtagagacca
     7261 tagtagacca gcaaaacggt aacggctagt tggttaagat tgctgagata ctggtcgata
     7321 aagtgggaag ccacgagggg tatgacactt ttaatgaccg tcgtcgctag gagaaaactg
     7381 agtgccaaaa agatcaggag tccataagac ttgagataag acatcaagcg cttcaataca
     7441 gcccattgtt cttgtttatt ctgcatcttc ttctcctttc atttctaact gctgagactg
     7501 gtaggtttgg gcataccagc catccatcgc tagcaagtct tcgtgcctgc ctcgttcgat
     7561 aatttgacca ttttgtagaa ctaaaataaa atctgcatgg acaacagcac tgaggcgatg
     7621 ggcagtgata atggttgtct tgtcctttcg cgtctccttg aggttgtcga taatcgcata
     7681 ctctgtcttg gcatctacgg cggataagga atcatccaaa atcaagatat cagggtttaa
     7741 aatcatagcc cgactcatag ccaaccgttg cttttgacca ccagaaagac tgactccttt
     7801 ttcaccaatc agcgtatcaa atccttgagg catgtctaca atatcttggt aaactcgggc
     7861 tagcttagta gcttcctcga ccgctgaaag gggcaagtta ggattgccaa agcggatatt
     7921 gtctaggatt gaagttgcaa agagaaactg gtcctgagga acatagccca tgagactgcg
     7981 aaggtctgtc agacgatagt cccgaatatc gtgaccgttt agataaatgg cgcccttatc
     8041 cacatcgtat tcacgcaaga gaagcttgat taaggacgtt ttcccagagc ctgtctgccc
     8101 aaccaagccc agtgtttgcc cttttgccaa actaaagtga atatccgtca gtgtttcctc
     8161 attttcaaaa gcaaagctgt caatggcata ctccaaacgc ccattttcaa taccatccag
     8221 aggaaactca gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta
     8281 agaaaccttc cctcgctgag tagtattaaa gaggaagccg atggccataa gaggccagac
     8341 cagcatatcc aaatagctga taaaggtgac cagattccca actgtaatct gcccttcctg
     8401 aaccatcaag gagccaacca aaagcgttaa aacataggac gaaccaacaa acaagagaac
     8461 catagggtca aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc
     8521 attgactgcc tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt
     8581 gatacctgat acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc
     8641 gccaaaggcc ttatgagtct ttctccctag gcgactagtc gcataggcca tgaaaggtag
     8701 ggggagaatg gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt
     8761 caccagagcc gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt
     8821 caaggcattg atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata
     8881 aaaggctgac gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa
     8941 gcaataagag gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa
     9001 ggctgcaagt agcaagtaaa ataggctaag aaggaggtcc tgctgggtta attgccccga
     9061 tgtgatggca tcaatgaccc gccccataac cataggagga atgagattga ggacggaaac
     9121 caagatcagg gccacaattc cgactagata acggcgtttt tctaacttga aaaaccacca
     9181 aagtttttga ataatggaca taaaatccct ttctgattgc aaatggaaac ctgaggccaa
     9241 tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc
     9301 tttgaggttg tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga
     9361 cgcggtttga agagattttc gaagagtaca agaccccagg tttttcttat tcataagtta
     9421 cgactgtaac agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc
     9481 cttgtttact gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat
     9541 ctacttgaat cacaccgtca gtcacaactg gatacttagg attttcatct cccatttgca
     9601 caacgatgag ttgcccattt tgctcttgca cagctcgttt gacttgcttc atctggaaaa
     9661 tcccttggct acgaagtttg agggatacat ccgatgcaga caaaccaact gaacgacagg
     9721 cttctgggtc aatattccca tttttgataa ggagagttgg cttaccatca atcaaacgtt
     9781 tcacaaagtg aacattgttg ttgagctatt tgagagtcaa gatcagtttg attaaaattt
     9841 cgatataatt aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa
     9901 ttcgactttc tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg
     9961 atctcccacc ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga
    10021 cttgtctact cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt
    10081 attgttagaa acttgattgt tttgataagt cgtgatgctg accaaaagca tagctaaata
    10141 aggccagagc tgaaattatg accaactcac gaaatttggt tcctttttta tcatggtatg
    10201 ccttgaaagc aaaaaaaact gtcacagcta ataaaacaat cccaaagcca accatgatac
    10261 cattttgctg accgatttgg ctgagtacat agtcataaga gtagaatttc atgtattttc
    10321 actccctttc ataaaatcat tcttaattat aaacgaaaga gagtaatttt tcaaaccata
    10381 cgttggggaa atagatcttt ttttggtata ataaaatcta taatctgaat gaaaaaggta
    10441 actttatgaa acttatctca tggaatattg attccctaaa cgctgcccta actagtgact
    10501 cagctcgtgc caaattgtcc caagaagtcc tacaaacctt ggtcgctgaa aatgctgata
    10561 tcattgctat ccaagaaacc aagctttctg ccaaaggacc tacaaagaaa cacgtggaaa
    10621 ttttagaaga actcttccca ggctacgaaa acacatggcg ctcttcccaa gagcctgccc
    10681 gtaaaggcta tgctggaacc atgttccttt ataagaaaga acttacgcct acgatcagtt
    10741 ttccagaaat cggtgcccct tctaccatgg acttggaagg ccgtatcatc actctagaat
    10801 ttgatgcatt tttcgtaacc caagtttaca ctccaaacgc tggtgacggt ctcaaacgct
    10861 tggaagaacg ccaagtctgg gatgtcaaat atgcggagta tttggctgaa ctagacaaag
    10921 aaaaaccagt ccttgcgacc ggtgactaca acgtagccca caatgaaatc gaccttgcaa
    10981 atcctgctag caaccgccgt tcacctggat ttactgacga ggaacgtgct ggatttacca
    11041 accttttggc aactggattt acagacacct tccgccatgt tcatggcgat gttcctgaac
    11101 gctacacttg gtgggcacaa cgcagcaaaa cttctaaaat caacaataca ggctggagaa
    11161 tcgactactg gctcacaagt aaccgtatcg ctgacaaggt cactaaatct gatatgattg
    11221 actcaggtgc tcgccaagac catacaccga ttgtcttgga aattgacttg taaggatttt
    11281 ctatatggac tacaatgcgg tcattcccga gtttcttgta tcgaatatcg aacagtcccg
    11341 gtccttctac tgtggtttac tgggttttag gattgaatac taacgtccag aagaaaactt
    11401 tctctttctc ttgaagagtg tcaactaatg ttagaggagg gaacaaagga tcaactagct
    11461 gaactgacct acccctttgg tcgtggagtc aatctctcct ttggcataaa ggatgttcca
    11521 aaactctatc aaaaagtgat ggaggcaaac tatcctattt atcgtctctt gaccaaaaga
    11581 aagtttcgtg tcagtgatcc ctatatctat cctcataaat ttgcagtttt ggatccagat
    11641 ggctattttt taagatttag cgagtagaat aataaaaatt gggaaaagtc tttaaagtta
    11701 gaaaaaggca tattgtcagg tgtctaaaaa cttgatagta tgccttttat gatggaaaaa
    11761 tcttctaata ctcttcgaaa atctcttcaa gccacgtcaa cgtcgcctta ccgtaggtat
    11821 atgatactga ctctgtcaat tctatccaca acctcaaaac agtgttttga ggttgtggat
    11881 agcttcctag tttgctcttt gattttcatt tagtataaat gttagcttac aatggagttt
    11941 ttgttcaccc tctcttcttt ttgttcgctt tttaaaccaa aacactaaca aaatagttga
    12001 tttataaagt tatttagtgt aaaataaaaa cattggctca agcctattta aaattgaata
    12061 tcgttttact tgtttatgtc gtgaattggc acgacgtttc tacaaggtgc cggaacacct
    12121 aacaataagt aagtcagcag tgagatatgg ccgtttttgc catgtctatt taggggactt
    12181 acttagagat taagtaggtc ttttttgaat atttttaata tttcccttaa ttagtgcgga
    12241 cgggaggtga aattatcctg tgaataattt caggaatcca gggaatttca tccctaattt
    12301 ttgagcccct agctctttca tttctaggct taggctaaaa tagttccccg aactatttta
    12361 ctctcaaaaa tcccgtcata gacaataaca agattattgt ctatgatacc actacaacgg
    12421 gaaatatttg ataagactcg cttcgctcgt aatagtttta tcaaatatat agtattagca
    12481 aaagggatca ctatagaaat atttaaacaa caagtaaatt aacttttaga ctttaggagg
    12541 tcttatgaaa ttattagaag agcgcatcct caaggatggg catatcttgg atgataacat
    12601 cctcaaggta gattcctttt taacccacca agttgacttt agcttgatgc gagagattgg
    12661 taaggttttt gcggaaaaat ttgctgctgc cggcattacc aaggtcgtaa ccattgaagc
    12721 gtcgggtatt gccccagccg tttttacagc tgaagcctta aacgttccca tgattttcgc
    12781 caaaaaagct aagaacatca ccatgaacga aggcatctta actgctcaag tctactcctt
    12841 taccaagcag gtgaccagca ctgtttctat cgctggaaaa ttcctctcac cagaggacaa
    12901 ggttttgatt atcgacgatt tccttgctaa tggccaagct gctaaaggct tgattcaaat
    12961 catcgaacag gccggtgcca cagtccaagc tatcggtatc gtgattgaga aatccttcca
    13021 agatggtcgt gatttgcttg aaaaagcagg ctaccctgtc ctatcacttg ctcgcttgga
    13081 tcgttttgaa aatggtcagg tcttatttaa ggaggcagat ctctaatgca aactcaagaa
    13141 aaacactcgc aagcagccgt tctgggcttg cagcacttac tagccatgta ctcaggatct
    13201 atcctggttc ccatcatgat tgcgacagcc cttggctatt cagctgagca gttgacctac
    13261 ctgatttcta cagatatctt catgtgtggg gtggcaacct tcctccaact ccaactcaac
    13321 aaatactttg ggattggact cccagtcgtt cttggagttg cattccagtc ggtcgctccc
    13381 ttgattatga ttgggcaaag ccatggtagt ggcgctatgt ttggtgccct tatcgcatct
    13441 gggatttacg tggttcttgt ttcaggcatc ttctcaaaag tagccaatct tttcccatct
    13501 atcgtaacag gatctgttat taccacgatt ggtttaacct tgatccctgt cgctattgga
    13561 aatatgggaa ataacgttcc agagccaact ggtcaaagtc tcttgctttc agctattact
    13621 gttctgatta tcctcttgat caacatcttt accaaaggat ttatcaagtc tatctctatt
    13681 ttgattggtc tggttgttgg aactgccatt gctgctacta tgggcttggt ggacttctct
    13741 cctgttgcgg tagctccact tgtccatgtc ccaactccac tctactttgg gatgccaacc
    13801 tttgaaatct catctattgt catgatgtgt atcatcgcaa cggtgtctat ggttgagtca
    13861 actggtgttt atctagcctt gtctgatatc acaaaagatc caatcgacag cacgcgcctt
    13921 cgcaacggtt accgcgcaga aggtttggcc gtacttctcg gaggaatctt taacaccttc
    13981 ccttacaccg gattttcaca aaacgttggt ttggttaaat tgtcaggcat caaaaaacgc
    14041 ctgccaatct actacgcagc tggtttcctg gttctccttg gactgcttcc taagtttggt
    14101 gcccttgccc aaatcattcc aagctccgtc ctcggcggtg ccatgctggt gatgtttggt
    14161 tttgtatcta ttcaagggat gcaaatccta gcccgagttg actttgctaa caatgaacac
    14221 aacttcctta tcgcagctgt ttcaatcgct gcaggtgtcg gtctcaacaa cagtaatctc
    14281 tttgtcagca tgccgacagc cttccaaatg ttcttctcaa acggaatctt cgtagccagc
    14341 ctactcgcta ttgtcctcaa tgccgtatta aatcataaaa agaaataaga aaaagaggtg
    14401 cgagcctctt ttttgtgtga caaaataaaa acatctacct attcatatat gctagtgtca
    14461 tagtcctgaa aatcatctgc atcaagaaca atttcacaac tcttatactt ttctcttaca
    14521 agtcgttcgg cttcatctgg attttcagcc tctatactta ctaaacgtga taaagtttct
    14581 gtaatttcta ctgtatactt tttcagtttt agattgcttt ccaataattc acctattaac
    14641 aataatctat gataggagct atgtagccac tctggcaatt tatctcctac ttcccaccca
    14701 tatttttcct tcatcaaagc tagttgtttt tcgtcaccaa atttcatatt ttcagataac
    14761 catctcacac aatcgggatc tgataaggta cagacgatta aacttaggtt atcgtaacgg
    14821 ctttcagttt cataatcagg ccagatgact tttaagaaat catacacctc ttctgatgca
    14881 acaagttgtt tcgttttcat aatttccgat actttcctct acctttaaat tctattattt
    14941 ctttgtctct taatatttga agctgttgcc taatcttttc tttgatatga ttgttcttaa
    15001 caaagatatt ttttaggtca ctttcaaaac gatacatatc ttcaagggta aattctgaac
    15061 cctctatctt atctatacaa tttagaattt ctattgtcca acctcttgat gacagagagc
    15121 tcttccttaa aaataaacct tgcttaaatt cttttgtaac tttttctgga tctctaactt
    15181 gtccatattg cacaagaaat atccttcctt tagaaggtac ttgtgataaa tcaatgttac
    15241 aaccaatcca acctgctcgt ctagcagttg gtgcaagtgg ttttctttga ataattgatt
    15301 tcggtgtaac aaattgcttc ggaaggacaa gaaagttatt tacctcaaaa ttttttgtgt
    15361 aagttaaaaa aaagaaatta ggattattat ctgcctgcac acgcttcatc atcgttgcat
    15421 aagcaccatc attgattgtt gatgaaaaat ttcctttttt gctctttagt tcaaactcct
    15481 cactacaatg attacagtaa aaatctgcta caggccgatt attttcaaaa tgatttaagg
    15541 gattgttccc acaattaggg caataagact gacgataaac ccaatcctcc gttaagatac
    15601 gtgccttttg gctattactt ttataggttt ctactaattc taaattaaag tgtaattcca
    15661 tttaaaaatt cctcactaat atgagaactc actcgatata agcaattaaa atctactata
    15721 actagtatac cacatatatg tacctattac atttgtattt caccactctc ttttatattt
    15781 ccttctaaca tatctcataa attaaaaatg agtgagataa atttatccca ctcacctttc
    15841 tttatatcct tacccgtctt tcctcagacc tttggcctgt gacaaacatg gtaaaggttg
    15901 ctttacagac atttctgccc tcttgattgg tgatatccac atccatcaca caggttgtac
    15961 gaccttgatg gacacattct cctttaatgg tcaatacatc gtcgagtttt cctgccttaa
    16021 ggtagttgat agaggattgg agtgtcaccc catcaagtcc cagcgagata accaccaaac
    16081 cactgatttg gtcacatagc gtgaatagat agccaccatg ggcattgcca tagtagttga
    16141 gcgacgagtt cactactttg gtcgtcacca caacgtgacc atctctcatt ttttcaattt
    16201 cgtaattttc aaaggcagat atagcgtcaa aatgaaagtc tttcatcgtt tcctcctgat
    16261 atttcaaacg acactatgat actacttttt ataggactgt gcaaggagaa agctcctagt
    16321 ctagtgaaat tccgacctgt tccacaaagc gcataaaggc tgtctgccct tgttctgtct
    16381 gcttgtagac tcctgcatcc tcaagtacac gcacaaagat agcacccaca gagtccttga
    16441 cgattgcaag ggctttttct ttatccgtta ggtctggatg ttgggatttg agttggtctg
    16501 cccactcctg atgataatcg gcaactgtaa cagcttctcc tacaagatag ctagcgactt
    16561 gctccacttc ttctttcaga cgtggtggca agattgccaa gcccatgacc tcaatcaagc
    16621 cgatattttc cttcttgata tgttggacat ccttgtgggg atgatagatg ccatcaggat
    16681 gctctgctga agtctgattg tctcgcaaga ccaagtccaa ctcaaactgt ccatcacgct
    16741 tacgcgctat tggtgtgatg gtgtgatgcg gcgtcccgtc tgtctctgct aaaatctgca
    16801 cactagaatc tgaatactga cgccattcct ggaaaatctt atcagctaag ttaatcaaat
    16861 cctctttgga atccgaagtc aagcgtagga cagacattgg ccacttgata attccagcct
    16921 tgacctgctc aaaaccagca aatcggaagg tcttttgcaa gggagccaat tccataggaa
    16981 atacgtgacg gcctccctga taatgatcgt gagttagaat agagcccccc acaatcggca
    17041 ggtcggcatt agatccagca aaatatcctg gaaactgctc tacgatagcc aacagacgtt
    17101 caaaactctg acgactaatg gccatgggac gatgctggcc atctaaaaag atacaatgct
    17161 cattaaagta agcatagggc gaatactgga acccccattc ctgaccaacc atttcaaaac
    17221 ggataatccg gtggttgctg cgagctgggt ggttgacccg accatggtaa ccctcattct
    17281 ctaaacaaag ttgacactga ggataattac tagcttgcac caacttggct accgcaatct
    17341 ctttcggatc cttttcaggc ttagagagat tgatggtaat ttcaagttct ccataatcag
    17401 atggaacacg ataagcgata tttttagcaa tggccttgag tttgatgtag tcatttttct
    17461 gactgagttg ataaaaatcc tctatcgctt gctcaggaga gtaggcatag gcttcccaga
    17521 agtcacgatt gacctgactc ggacaaggag tcaccaagtc catcagttca gtaccaagga
    17581 tttcacgcgc agtctgacta tcctcaatcg tctctaatcg aacggcttcc tcaactagct
    17641 gggccttgag gtcaatcaat ttatccagat tggtctcaac ttccaaaaca ccttctccca
    17701 ctcgtgccaa aacacgattg gtcaggtaga ttcgatccat ttcctcaaat gaactttcag
    17761 aaatgacatg tgttacaaat ttatctacta aggtcactat agagcctcct tttgactagt
    17821 caaggacgcg agtgccacct gcaacttcag cgatatagaa gcttggagcg tatccaacta
    17881 cttcctcgta gtgtttgcct acagcttcct taaaggcctc aacagtatct ttttgaacca
    17941 aggcaatggc acagccacca aaaccagccc ctgtcatacg agcaccgaga actccttctt
    18001 gtgcccaagc tgtgtgaaca agggtatcta attccaaacc agttacttca taatcatgct
    18061 ccagagaaac gtgtgacgca ttcatcaaac gaccaaatgt ttccaaatca cctgcttgaa
    18121 gggctgcttg agctttaagg gtacgttggt tttcaagcac agcatggcga gcacgtttca
    18181 aacgattttc atctttaatt agatagctat attggtcaac ggcccactcg tccaattcac
    18241 ccagggtctg aatatccaag gcaacttgca attcttccac tgctttttca cactcagcac
    18301 gacgttcatt gtatttagag tccgccaatt cacggcgttt gttggtgttc atgataacaa
    18361 cgacattgtc cttcaaatca agtggcacca aatcatactc taaggtgttg gtatcaaggt
    18421 aaatagcacg ttgatcagcc cccataccaa tagcaaactg gtccatgata ccagagttga
    18481 ctccgataaa gttgttttct gtttgtttgc cgattttaac caaatcgaga cgctctaatt
    18541 ttaaatcaaa gagatgctct gccacgactc ctgtcaagag ctccaaggat gctgaagaag
    18601 acaagccagc accatttggg atattcccat aaacataaaa atcaaaacct ttgtcaatca
    18661 cgtgcccagc ttcttgcaag aaatgaagaa ccccttttgg ataattggtc cagttgtgct
    18721 ctttttcaaa cttgaggtca gcgagaggca cttcgataat gcccttgtcc tcaaagttag
    18781 ctgagtagaa acgcaagact tggtcgtcac gcttacgagc tgcaccgtaa gttcccaagg
    18841 aaatagcagc aggaaaaacg tgcccaccgt tgtagtctgt gtgttcacca atcaaattaa
    18901 tacgacctgg tgaaaagaag gtttggtctg cttcttgacc aaaaacagca agaaagtctt
    18961 tgcgaaggac ttcagtagta agatgttgtg ccatatgaat tctcctttga ctgtccgtta
    19021 agccatctta acgtgtaatc gttttcttct attgtatcca aggaatttcc caaggtcaat
    19081 cctttttact aaaattttag taaaacatca gtaaaaagaa gaaaaatatg atatactaac
    19141 ctaatcaagg aggatttatg gctaccttaa aagacattgc acagctagcc tctgtctcta
    19201 tcgcgaccgt atcccgtgtc ctcaaccgcg accagagcct atctgttaca gaagaaacca
    19261 gacaccgtat tttaaccgtt gctgaagagc tgggctacac caagcacctc aagacaggcg
    19321 agtcccataa acccaagcaa aagattgcca ttattcaatg ggtcagcgaa caaggggagc
    19381 tagacgacct ctactactac cagattcgcc taggaataga aaaaagagcc caagagttgg
    19441 actacgatat cttgcgctat tttaatgacc atccttttac cctaagcgag gaagtgattg
    19501 ggattctctg catcggaaaa tttagccgag ctcagatttc tgcctttgaa gaataccaaa
    19561 agcctcttgt atttctagac agcgatacac tttccctggg acatacctgt attatcacgg
    19621 atttttacac tgctatgaaa caggttgtcg attatttcct cagtcaaggg atggaccgca
    19681 tcgggattct aacagggctt gaggaaacaa cagaccaaga agaaatcatt caggacaagc
    19741 gtctagaaaa cttcaaaaac tacagtcaag cgaggggaat ctatcatgat gaactggtct
    19801 ttcaaggaag atttactgcc cagtctggct atgacttaat gaaggaggcc attcagagct
    19861 tgggagacca acttccgcca gcatttttcg cagccagcga tagtttagct atcggtgccc
    19921 tccgtgccct ccaagaagct ggaatcagcc tgccagatcg cgtcagcctc atttcattca
    19981 acgacaccag tctgaccaaa caggtctatc ctcccctctc tagtattaca gtttatactg
    20041 aagaaatggg gcgagcaggt atggatattc ttaacaagga agtcctccac ggtcgcaaaa
    20101 ttcctagcct gaccatgctg ggaaccagac tgacattaag agaaagtacc ctaaatcaag
    20161 aataggataa cataaaaaac gaatagagtt ctaaaactcc tattcgtttt ttattcgatt
    20221 acaatcatag acttaattgt cttacgttca tccatatctt tataggcttg gtcgatatct
    20281 tccagtttat aacttgaagt aaagacgcga cctggattga tatcaccatc aaggacggct
    20341 tttagtaaaa attgcttatc gtatgttgta gcagaagctg ccccacctgc tacagagatg
    20401 ttttgcataa atgtcgaacc aagagcacga ttattatagt gtgggactcc tacaaagccc
    20461 atacgccctc cattatgaag aacacctagc gcctgttcta tagcagcctc cgtaccaaca
    20521 cattcaagtg ctgcgtctgc tcctccgccg aggatttcac gcaccttggt aattccttct
    20581 tgaccacgtt ctgcaacaac agctgtcgca cctgactcca tagccatctt ttgacggtct
    20641 tcatgacggc tcataaggat aatttgtgat gctccacgca tcttagccgc gatgacagca
    20701 cattgaccaa cagccccatc accgataaca acaaccttgt cccctttttg aacatttgca
    20761 acacgcgctg catgatagcc tgtcggcatg acatctgcaa gagtcaaaag ggacttgagc
    20821 atcccttctg tataatcaga aggttgacca gggattttaa ccagcgccca gtttgcatag
    20881 tggaagcgaa tatattctgc ctgaaaatca ccccccaaat tattaccaat atgattgtcg
    20941 caagaaccgt caaatccagc aagacaggca tcacactcac cacatccatg tgtaaaaggg
    21001 acaatcacaa aatcacctgg tttcaccgtc gtaatggctt ccccagcttc ttcaacaatc
    21061 ccaatcgctt cgtgtccact atttttatgt ccagctttcg tttctggatt acggtacctc
    21121 cataaatctg aaccacaaac gcacgcacga accacacgaa taatcacatc atccgcttct
    21181 attatttgcg gacgttcaat gctagcaagt ccaacctgac ctgcctttgt atatactgct
    21241 gatttcattt aaaattttcc ttccttataa agtttaattt tgagatttaa acgatttaaa
    21301 gctgtctgta gctgagacaa gcgctcctct aatttttgct tttcctcttc taaaatacca
    21361 agcctctcct ctctcgtttc atctcccttt tggtagagcg acatatagtc aactaaacta
    21421 tctacagaga cacccgccga acgaaaacac ttaataaatt ccagcgcttc gatatcctga
    21481 tcttgaaaat cacgaatccc agtagcagta cgagtaatcg gtggcacaag accaacccgt
    21541 tcataatacc gaatcgtatc cgctgaaatt cccaacaaat cactggcaga tttaatattc
    21601 acacgctaac ctcctctcat ttcattcact gaattcacgc tattctaact cacttatctt
    21661 attatataac tttgagttga ctccaagtca agcattttgt atctaatcga aaaattttta
    21721 tcattaacaa tcatatatct ggagtttata caatgctctt ctcttaccaa tttttgaaat
    21781 atttaaataa taaagaaatt actctattcc aaataagata gtacccaagt atttttcact
    21841 tttttctaat gttgatgctc ataactccgt tccaagtcac acacctttcg cttatgggtt
    21901 tggtgagttt ctaggtcagc atcaatttca atggtaatat tttgaaaacc acaatctttt
    21961 aggaaaattc gaatagactc tttacaagtt tccatatgtt ccatttcttt tagacaaaca
    22021 tgtacaatgg catttttttc caaagcatcc atagtccaga gattaagctg attaaggctg
    22081 gccacattgt ccaatcgctc caggccactc tttacttgct tgatatcaag accttctggc
    22141 acagcatcca agaaaatctt gagtgtagac caaaaacgtg gaagggcttt tgaaagaata
    22201 aagaaagaaa tgacaaggga caaaagagga tctaggatat accagtccgt aaatcgaaga
    22261 acaatcgcca tcaggataac agctacccac cctagcgtat cttccagaaa atgcaaactc
    22321 agaatagact cattctttgt ctttccctta ccaaccacca gactcgctaa cagattgata
    22381 gtaatcgcaa taattcctaa ccagagaatc ccctcatcat tgactggttg cggatgcaaa
    22441 atcttcgtga cattttccaa aatgactaga acagagcccg ttacgagaat cacagctgtt
    22501 accaaggctc ctagcaggct aaaccgctta tagcccaagg tgtactgatt gtcttcttca
    22561 cgattggaga ttgtttctag aaaagctgat attccaattg caatcgcatc tcccaagtca
    22621 tgcacagagt cagcaagaac agcgctagaa ccaaatactc cacctgcaat aaactcaaca
    22681 atggcataag tcaaatttaa gaaaaaagcc acccaaacag catattttgc cttcatattt
    22741 ctcattcctt tgttataata gatttatgaa caccttgttc attatcatta tccactaaaa
    22801 ctcaaagaaa ggatagaagc aaaacgtcag ctttattcag ttctgaacaa tttgccttaa
    22861 gtgtccatat gactaacatt gaccgccgta tcagcaaaac caaaaaagcc atctatcaag
    22921 cttttataca acttttgaat gctaagggct acgaggccac tactgttcag gatatcattg
    22981 atctcgcaga tgtgggaaga tccacctttt actgtcacta tgaaagtaag gagcttcttc
    23041 tggaccagct ctgccgctac ctcttccatc atctttttga aagagagcaa gccatttcaa
    23101 ccgaggacta cctcgcccac ctctttctcc attttcataa aaaccaagac catatcacca
    23161 gtctgctatt ttccaaaaat gactacttcc tccgtcaact ccataaagag ctagaacacc
    23221 atgtctattc cgtgctagct gataatttaa aagaagccca ccctaatatg cctacttctt
    23281 acctccaaca cttggtcgtg tccaacttta tcgagacatt gacctggtgg ctcaaaaaag
    23341 gtcaagattt cacaggccag gaagttgtcc aattttatct agaccttctc attcctaaaa
    23401 attgaatata gagtaaagct cagttgtctt atttctaggt tactgagttt tttatctttt
    23461 caacaacaaa agaggacccg ccgatcctct ttttcatact ataaatcctt gattatcaac
    23521 tatatctgtt ttaatcgaaa tctcaaaaca gcactttcaa acatcttttc ctagttaagt
    23581 aaatcagtat tctgcttagc tgccttgctc cattgatacc aaccaactag actgttaatg
    23641 agataaatta gatatttccc ttgaatttgc aggctttctc cccaccagag atagattgaa
    23701 aaaacattgg tagccgccca gaatatccac tgttcacggt aaacagctgt catgaggatt
    23761 tgccctaccc cattggttgc atctgtgatt gaatcacgat agggacgatt ggcaccaata
    23821 gactgataaa tgaagccaaa ggccaaccac caaagcacac taatggaaag atactttgtc
    23881 cagcccttgc cgtccagttt acgcgcgaca aactcctgct tttccttctt aaactgtgcc
    23941 tgataaatcc aaactagaag tccaattggc tgcatgactg tgaagtaaag tgtcgtcagc
    24001 acctcaccat aaaagccttt ctgtagggcc aaaataaggt aaataacaga gttaatcaag
    24061 ccaaaaagat aattacttgc tcgaccttcc gatacaaaga ttacacagat aatccctgtc
    24121 aagctacaaa tcatcccaat ccagtcaaca atacgatgtt cgtaaaccaa ctccagccag
    24181 agaggaaaac ttcctaaaac cagcaaataa atccactggg caaaactacg atgggcaaag
    24241 aggtcatccc agatagcctt catagttcct gaaaatccta aatcagccat agccgcaacc
    24301 atacgacggt aaccacctga catttcacct agggttgttt tgatattttc aattttcttt
    24361 tgcaaataag tatgcatcat ttctcctttt gtttttaaag agccgtgtct ggatagactt
    24421 tcggacgcaa cgctctatta gataatgaac tgcctataca caagatttct aaccttagtc
    24481 gacatgagct aaaacctctt atttgttaag tagttcacaa aatattatac acctatttta
    24541 tgaatagtca actgtcttta cagtaaaatt ttagaaaatc atgaaaattt tctctttctt
    24601 tccattttaa gtgacattca gtcattctca catcaaaaaa gcccagacga aattgtctga
    24661 gcattctttt atctagtcgt ttaaggaagt tgagttcagt atgtttaaag tctctgtccc
    24721 atcatttctt caacaaacct tgttcttgga gaaactcctt ggctacttgc tttgctgact
    24781 tgccttcaac accgacttgg tagttgagct ggctcatctg gctttctgta atcttaccag
    24841 ccaatgtatt aagaactctt tccaactctg ggtgtttctt gagaagagct tctttcatga
    24901 gtggagcccc ttgataaggt gggaagagtt gcttgtcatc ttccaagacc tgtaaatcat
    24961 aacgctccaa ttccgcatca gtcgaatagg catccgtgat ttgaatatcc cctgactgaa
    25021 ttgcctgata acgaagagct ggctgcatag tcgccacatt gagattgaga ccatacattg
    25081 attgcaagcc cttatttcca tcttcacggt cgttaaactc aagcgtaaag cctgccttca
    25141 gctgcccttc cacttttttc aaatccgaaa tggtcttcaa gccatattct tgagcaatct
    25201 ttttcggaac agctacagca taggtatttt gataagacat aggtttgaga taggctagat
    25261 gatcctgctt ggcaatgcca tcacgcgcca cttgataaac ctgctctggc tcatgactca
    25321 ccttgggtga tggttgaagc aaactttcag tcaccgtacc ggtaaattca ggataaatgt
    25381 caatatcacc ttttttcaga gcttcataaa ggaaacttgt cgtcccaaaa ttcggtttaa
    25441 cagtcgcagt catgctggta ttttcttcaa tcagcaactt atacatatta gccaaaattt
    25501 ctggttctgg gcctattttc ccagcaataa tcaagttttc cttctctttt tgagccaaaa
    25561 gagctggact ataagacaga cccagtaata aagccaccaa ggcaaaacca gagaaaatcg
    25621 tccgcaattt cgctttttcc attactttta gtaggaagtt aaaggcaata gctagcactg
    25681 cagaagaaag ggccccaatc aaaatcaaac tggcattatt acggtcaatt cccaacagga
    25741 taaaggaacc cagtccccct gccccaatca aggtcgccaa ggtagccgta ccgataatca
    25801 agaccgctgc cgtccgaatt ccagacatga taacaggcat ggcaagtgga atttcaaact
    25861 tcttgagacg ctcccatctg gtcatcccaa aggcaatccc agcctcttga agactcggat
    25921 caattccctt cagcccagta atagtatttt gtaaaatcgg aaaaatcgca taaatcacta
    25981 gagctgtcaa agccggcaag gtcccaattc ccatcaaagg gataaagagc cccaacaagg
    26041 ccagagacgg gatggtctgg aaaatacctg caatctgcaa gacccagtcg gccagcttct
    26101 catgatagcg aagaaaaaca gccaagggaa tcgcaagcaa aatagctagt aacaaggtca
    26161 aaagtgacaa ctgcaaatgt tgagatagag ctgtcaacca atcactaaaa cgatcctgaa
    26221 aagttgcaat taaattagtc atgaacacta cctccaaaca agtctgctac aaagtctgtt
    26281 gcaggcactt ttaaaattgt ctcgggattc gctacctggc gaatttctcc atcctgcaag
    26341 acagcaatac ggtccgccaa cttcaaggct tcatccgtat catgggttac aaaaatcgtt
    26401 gtcatcccaa actctttatg caattctttt gtcagaacct gcaactgttt tctcgaaata
    26461 gcatccaagg ccgaaaaggg ttcatccatg aggaaaatct tgggctgacc aatcatagct
    26521 cggacaatac cgacccgttg ctgttctcca ccagataatt cactaggtaa gcgatgccca
    26581 tactcggcta ctggtaaacc aaccttagcc aaaagctctt ctgttttctt cgtaatttct
    26641 tccttgctcc accccttcat ttcaggaatg agagcaatat tttccgcaac tgttagattt
    26701 ggaaaaagag caatagcctg taaaacataa ccagtagaaa gacgaagttc acgctcatca
    26761 tagtctttga tgcgcttccc atccatataa atatttccat cagttggttc caaaagacgg
    26821 ttaatcatct tgagcatggt cgtcttacct gacccagaag gccctactaa aaccataaat
    26881 tccccatcct caatctgtaa gttgacatct ctcaagacat ccttttctgt gtagcgcagt
    26941 gctacatttt tgtattcaat cattctttgt cctcaattta aaacttccct cgattagtca
    27001 agtcttctac cttaggcatg acttccttat tatcccaatg ctccacaatt ttcccgttct
    27061 ctaaacggaa gatatcgtac tgggcataag caacgccatc aatctgagtc tgaccatagc
    27121 taaccacata gtttccttgt cctaagagtt ggaaaacaaa gtcaaaagtg acactatatt
    27181 cagccacata gtttttataa gcagcacttc cttgtccaat ctcatgatta tgctgaatca
    27241 aatcgtctgc cacataatca ctccactgct ctagctcccc attttggaaa gtttctgtca
    27301 agaaacggcg aaccagcttt ttattttctg ctttcttgtc caaatccttg atttcaaaat
    27361 ctccaaaaat ttgatctagt tggtcatttt caggtgttcg atagtagtca atgacatccc
    27421 aatgctcaac aatacgacca ttctcatccg cacggaaagt atccgtcgtc acccattgag
    27481 cttctccacc attcagatat tgatgaacat gaacaaagac cagattgcca tcctcaatgg
    27541 tgcggacaat cttaatctga cgctctggat gacgctcaaa gaaatctgca aagaaggctg
    27601 caaatccttc tttcccgtca ggaacacctg tcgaatgttg gatataggta tcccctacag
    27661 actgggcttg agcctcagca actcgtccgt cttgaatggc atggatgtat aggttgtgag
    27721 catttttcac ttgttgtgac atattctaaa cctcattttc cttctctttc agatttgcca
    27781 aaattctttc ttgaaaacct tcaaattggt gaatttcttc ctctgaaaat cctttgtaaa
    27841 agatagtatc caatttctga ctgacacgat gccccacttc tttctggaac ttgcctaact
    27901 ccgttaaaac taaatacttc ttacgcttgt cttttccaca cggactaaca attacaagct
    27961 tttgttcctc tagctttttt atcatagtcg tcagcgtatt attcgcaagc ccagtcgcaa
    28021 gcgcgatatc tgtcgcagtt gcgcagccag tttcactatt ccataaaacc gctaaaatct
    28081 tgccctgttc acccctataa agagcctcag gatcttgact cagtaacttt tgaaaaatcc
    28141 gcccattcaa caaacgaata tgatgggcta gcaaatgact atctttcata acacctccaa
    28201 tttatttcga tatcgaaatg aataaaataa ttgtaacact catcgttcta actgtcaact
    28261 atttcgattt ggaaataatt tttgataatt attcacacca ccatactccg gctcaactaa
    28321 cttttaacga gagtttctaa attccttcgt cctccagtct acaaaagcct tccatccgta
    28381 ctatcctatt ttttatgagg ggacacattt ttcctatcag atcatttatt ttaaagatag
    28441 aagtaaatca taattgcttc catctgttct tttatagtat attgaagttg gactagggca
    28501 ctgtatcttc taaaacattg atagaaagcg atttgaattt cccaatcaat ttgttcgtat
    28561 ttatagcatt ttgaaactag aataggacgc catgactgct aaaagatttc tataaattca
    28621 tttgatttcc ctaatcaatt tgttcatatc ttatttcatt ccgctataat ttcaccttac
    28681 cctatctttt tcgtagcacc cttcaaacag cctatcccct accgtttgat gattcctcac
    28741 ttcactccac ttccattaca gaagtttctt cactactatg gtctcggctg acttctcatg
    28801 attccttgtt actactattt gaacgctcac gagataggtc ttataaaaaa tgctttgatc
    28861 cacaatggaa tcaaagcatt ttaaaaagtt cctcatacat aagcgcagaa gtcgcagttc
    28921 ctctgtactt ggcttcttct cttttgacaa agcgagccaa gttgagcaac tcaggtgctg
    28981 gatgtttggg atttaggagc aattcacgat tgaccaggct tgagagacga actgcctgca
    29041 attgctcatt tgtagtaggc agttttttag tagtctctag gagagcagca actaaatctt
    29101 cactcaaatc atgtcgagca tgattgtaaa gatcttttat aaggctttct aggtttggtt
    29161 ctaccatccc taccacctcc cttatggttt aataatgttt aatcaaatca accgttgaac
    29221 gatccaattt cttcaccaag gcttgtaaga aagcttgcgc ttctaggaag tcatccattg
    29281 catagagggt ttggtgagaa tggatataac gagcgcagac accgatagtt gttgatggga
    29341 caccaccatt tttcagatga gctgcacctg catctgttcc gcctttacca cagtagtatt
    29401 ggtacttgat accagcttct tcagccgttg tcaaaaggaa atccttcatc cctgggagaa
    29461 gcaagtgacc tggatcatag aaacgaatca aggttccatc tccaatcttg ccttgaccac
    29521 cgtagacatc acctgctggt gagcaatcaa ctgcgaggaa gacttctggg tcaaacttgg
    29581 ttgtagaggt atgagcgcca cgcagaccaa cttcttcttg gacgttagaa cccagataga
    29641 gttcattgcc gagtttttga cctgataaag cttcagctag ctcgcttacc atgaggacac
    29701 cgtagcggtt atcccaagct tttgagatga tatttttttc attggctgtc aaaattgcag
    29761 aactatctgg tacgatggta tcaccaggac ggatgccaaa actttctgcc tcagccttgt
    29821 ccgcaaaacc accatcaaaa acgatatcgg caatggctgg catggttggt cccccctttc
    29881 cacgagtcaa atgcggagga acagaacctg aaatcacagg aatttcatga ccatcacgag
    29941 tcaagagttt gaaacgttgg ctgctaacca ccatggggtt ccagccaccg atttctacga
    30001 cacggaaggt accatctggc ttgatttcgc tgaccataaa accaacttcg tccatatgag
    30061 aagcgaccaa gacgcgcggt gcatccacag cttctgaatg tttgatacca aaaataccac
    30121 ccaagccatc tgtcaccact tcatccacat gcggtgtcaa cttttcacga agataagcac
    30181 ggacaggcgc ttcatgacct gagactgcag caagttctgt tacttcttta atttttgaaa
    30241 ataatgttgt catttcagtt ccttctttct ttcatccatt ttaccacttt ttataggaga
    30301 aggatagtgg gaaggtggat ttctaagtta gtatcttagt cctgctctat cttagaaaag
    30361 gatagtattc tcttgcatgt agtgcaaaat ctagtaaaca ttccaaaatt aactcgaata
    30421 tttatttcca aacaaaaaaa caatacacca tcaaagttgt ttggattttt catgaaattt
    30481 acagaaaata gttgacttcc ctttcttctt tctttaaata tatagttggt tgagtttgga
    30541 atagtacgct gtagctgctg aaacatttct agaaattaat ttgactttcc taatagagtt
    30601 gttcatatct tatttcaatt tactatagta caaaactaga aaaggaaaaa atcatgacca
    30661 aaacaattct tgttacaggt gggactagct acattggctc ccataccgtt aaagctcttt
    30721 taaatgctgg ctataaggtg catgtcctcg ataatctctc cacaggaaat cgagcggctg
    30781 tggatagtcg tgctagcttt aaagaactgg atgtttatga tgctagcgcc ttaaaggctt
    30841 acttagaaga aaatcagatt gatgctgtcc tccattgtgc aggtgaaatt gttgtgagcg
    30901 aaagtattga aaatccaagt aaatacttca ctgccaacgt tgctggtatg aaccaagttc
    30961 tcaaagtctt atctgaagtt ggcattcaaa aaatcatgtt ctcttcgact gcttctctct
    31021 atggaaataa ctgtattgac aagccggtga ctgaagatac cctgctcgac cctgtcaacc
    31081 cttatgcaga gacaaaactg atgggcgaac gaatgattta ctggatggcc aatcgctacg
    31141 actggaaata tgttattttc cgttacttta atgttgctgg ggctgaaatg gatgcttcaa
    31201 acggtctgcg tgtgaaaaat ccaactcaca tcattccaaa tatcaacaag accgcattgg
    31261 gacaaaatga tagcttaaaa atatttggag atgactacga tacacgtgac ggttcatgta
    31321 ttcgagatta catttatgtc ttggaccttg cataggctca tgttaaagga atgaactacc
    31381 tatttcaaga agacagttct tctcaaatct ttaacttagg aactaaaaaa ggctatacta
    31441 tcaaagaaat ctttaaaact gctgaagaat tactaaatta aaaaatccca cacgagattg
    31501 ttgctcgacg tgctagtgac ccagccagtg tcctagcaga tgcttcaaaa gctaaacaat
    31561 atcttgattg gacggctagc tactccctcg aagatattat tttatcagat taaggtaaaa
    31621 acattttaga ataggataac aaaggagaaa gtcttgttgc tctctccttg ttgtatttat
    31681 taaattgtca gaaattttat tgacagatta gaaaaataat gttacattta tatccgcagg
    31741 tatctttcga taccaaatct acatgaaagg acggggtatg aaactttctc attatttaat
    31801 tggcttactt ctactcctag tctttctctc tattagcatt gggaccagtg atttttcatg
    31861 gggaaagcta tttgatttcg accagcagac ctggctcctc tttcaagagt cccgtctccc
    31921 aagaactatc agtattctcc tgactgcctc tagtatgagt atggcaggcc ttctcatgca
    31981 gactattacc caaaatcagt ttgctgcacc gagtacagtt ggaacgactg aagccgccaa
    32041 actgggaatg gtgctgagcc tttttgtctt tccatcggct agtctgaccc aaaagatgct
    32101 cttcgctttt gtttcatcca tcctattcac cctcttcttc ctagccttta tgaccatttt
    32161 tactgtaaag gaaaggtgga tgttgcctct gattgggatc atctatagcg ggattatcgg
    32221 ctcagtcaca gaagttatcg cctatcgttt caatctggtt cagagtatga ctgcctggac
    32281 ccagggctcc ttctccatga ttcagaccca tcagtatgag tggctcttct taggcctcat
    32341 catcctgata accgtttgga aattatccca aaccttcacc atcatgaatc tagggaaaga
    32401 aaccagcgag agtttgggga tttcctactc cctacttgaa aaactggccc tctttctggt
    32461 ggcgctaacg acaagcgtca ccatgattac cgtgggtggc ttaccatttc tcggagttat
    32521 cgttcccaat cttgttcgca agcgctatgg agataatcta agtcaaacca aactcatggt
    32581 cgcactggtt ggtgccaatc tagttctggc ttgcgatatc ctatcccgag ttctgattag
    32641 gccctatgag ttgtctgtca gtctcttgct aggaatcatc ggtagtctcg tctttatcct
    32701 acttctctgg agagggggac gaaaagatgc agactaaaag caaacatacc aagctcttct
    32761 ggattctcat tattcttgcc atcggagctt gtcttctcta cttttggccc atcactcact
    32821 tgtcagcctt tgcttggaag ttgcgttccc aaaagatcat cgtttatctc ttggtagcca
    32881 tcgcgactgg gatttcgacc attagttttc aaaccctgac ggaaaatcgc ttcctgacgc
    32941 ctagtatttt gggaattgaa tccttctacg tcctactaca aaccctacta ctggtttttg
    33001 aaagcaagtt tcttcaactt ggcaaatccc ctatcttaga attcctagtc ttacttcttg
    33061 tccagtccct cttctttctc gccttacaag gttacttgaa gacactgatg aagcaagacc
    33121 tggtcttcat cctgctgatc tgtctagcgc tcagaagtct ctttcgaaat atcagcacct
    33181 tccttcaagt cctaatggat ccaaacgaat acgataaact gcaaaatagt ctttttgcct
    33241 cctttcaaca tcttaacact tccatcctag ccatcggttc tctgatcatc ctcgctttga
    33301 caatcttttt ctttcgaaaa gcagtcgttc tagatgtctt gcacctgcaa agagaaacgg
    33361 ctcagatatt gggactcgat gttgaaaaag aacagaaaga gctcctctgg ggaatcgtgc
    33421 ttttgacctc aacggccact gccttggtag gacctatggc cttcttcggc tttatgctgg
    33481 ccaacctcac ctacctgatt gtcaaagact atcagcacaa gttactcttt atagtggcca
    33541 ttctggttgg atttattagc ttaaccttgg ggcaagcctt gattgaacga gtctttgcac
    33601 tggaaattcg tatcagtatg atcattgaga gtgtgggtgg cttcttattc tttatcttac
    33661 tatataggag ggctcgtcag tgaaactgga aaacattgac aaatccattc aaaaacagga
    33721 tattttgcaa ggcatttcgc ttgaagtcag tcctcaaaaa ctgacagcct ttattggtcc
    33781 aaatggtgct ggaaaatcga ctctcctctc catcatgagc agactaacca agaaagatca
    33841 gggagttctc agtatcaaag gacgtgaaat cgagagctgg aattcgcaag aactggccca
    33901 agaactaacc atcctaaaac agaaaatcaa ttaccaagcc aaattgactg ttgaagaact
    33961 ggtcagtttt ggacgttttc cctacagccg aggtcgactt agatcagaag actgggaaaa
    34021 aatccgagaa actctgaact atttggaact gaccaactta aaagaccgct acatcaatag
    34081 cctgtcaggg gggcaactcc agcgcgtctt tatcgctatg gtactggccc aggatacgga
    34141 ctttatcttg ctggacgaac cactcaacaa tctcgatatc aagcaaagcg tcagcatgat
    34201 gcagattctt cgacgactgg tggaggaact cggcaagacc attatcatcg tcctccacga
    34261 tatcaacatg gccagtcagt atgcagatga aattgtcgcc ttcaaggacg gccaggtctt
    34321 tagcaaggga agaaccgatc aaatcatgca ggctgacctg ctcagtcaac tttatgagat
    34381 tcccatcacg ctagctgata tcaatgacaa aaagatctgt atctatagct agtaacataa
    34441 aagctcaagt tagagaacct tcagtctctt agtcaataag attaagagac tccctaaatc
    34501 gttatcacat tttaaaaagg agaaattatg aaaacatccc ttaaacttta tttcactgcc
    34561 ctagtggcca gcttcttgct cctacttggt gcatgtagta caaactcaag cactagtcag
    34621 acagagacca gtagctctgc tccaacagag gtaaccatta aaagttcact ggacgaggtc
    34681 aaactttcca aagttcctga aaagattgtg acctttgacc tcggcgctgc ggatactatt
    34741 cgcgctttag gatttgaaaa aaatatcgtc ggaatgccta caaaaactgt tccgacttat
    34801 ctaaaagacc tagtgggaac tgtcaaaaat gttggttcta tgaaagaacc tgatttagaa
    34861 gctatcgccg cccttgagcc tgatttgatt atcgcttcac cacgtacaca aaaattcgta
    34921 gacaaattca aagaaatcgc cccaaccgtt ctcttccaag caagcaagga cgactactgg
    34981 acttctacca aggctaatat cgaatcctta gcaagtgcct tcggcgaaac tggtacacag
    35041 aaagccaagg aagaattggc caagctagac aagagcatcc aaaaagtcgc tactaaaaat
    35101 gaaagctctg acaaaaaggc ccttgcgatc ctccttaatg aaggaaaaat ggcagccttt
    35161 ggtgccaaat ctcgtttctc tttcttgtac caaaccttga aattcaaacc aactgataca
    35221 acatttgaag actcacgcca cggacaagaa gtcagctttg aaagtgtcaa agaaatcaac
    35281 cctgacatcc tctttgtcat caaccgtacc cttgccatcg gtggggacaa ctctagcaac
    35341 gacggtgtcc tagaaaatgc ccttatcgct gaaacacctg ctgctaaaaa tggtaagatt
    35401 atccaactaa caccagacct ctggtatcta agcggaggcg gacttgaatc aacaaaactc
    35461 atgattgaag acatacaaaa agctttgaaa taagccactt caaactcaat ttaatactca
    35521 atgaaaatca aagagcaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgag
    35581 gttgcagatg aaagctgacg cggtttgaag ggattttcga agagtataaa attttgacat
    35641 tctaaaacgc atcctatcaa gttcactcaa acctgatagg atgcgttttt atcattttga
    35701 aatctattta ccccacctca ttccccttct tgatttcgtt taagggaaaa gtggtctgga
    35761 acggggtcct tacctgtttt cgaccaggga tgacaacgta aaatccgagc caagcccatc
    35821 aataccccct taaaaccatg tttttcaata gcctgaatca tgtagttgga acaagtcagc
    35881 tcaaagcgac aagagggtgg aaagactggt gagataaaac gttggtaaaa gcgcacaggc
    35941 gctattaaaa ttcgtttcat tatttcttag ttacagccat ggtgtgtagt tggctgattt
    36001 cttttttatt aagacgacgg gattctcctg gacggagtcc tgtcaagtct aggtgtccga
    36061 aacgagtccg agacaactta tctacttgga gaccaacagc ttcaaacatc tttttaacct
    36121 gatggttacg cccttcatgg atggtcaact gcaccacaga gcgatttttg actgggtcca
    36181 ctttgagaat ttcataaaca gctggcttgg ttttcttacc atcaatctca agaccacggg
    36241 tcaaggggcg gagattgtcc ttattggcca cacctttaac acgcgcgaca taaaccttgt
    36301 caatctcatt acgagggtga atcatctcgt ctgtaaagtc cccatcattg gtcaaaatca
    36361 agacacctga tgtatcccag tccaaacgac ccacagggta aatacgttct ttgacattgg
    36421 gcaagaggtc gacaaccgtc ttgcgaccct tatcatctgt cacactggaa atcacaccgc
    36481 gtggtttgtt aagcagatag tagacctttt cttcgttgta gataggttga ccttcaactt
    36541 cgaccttgtc gcctgacttg atagtggttg ctagttcacg caccacttgg ccgttaaccg
    36601 tcaccaagcc ttgcttaatc agctcttctg cttttctcct actggccaca cctgcgtggg
    36661 caatatactt attgattctc atcttcttct atcctttcac caaataattg gctttcttgg
    36721 gcttgaatct caagctcatc aatcactggt aattcttcta aatggtttat ccccatgtaa
    36781 tctaggaaat aatccgtagt cacatagagg ttggggcgcc ccaatacttc ctttttcccg
    36841 tcttccttta tcaggtcaaa agcctgcaac tttgccaagg ctccactcga gttaacccca
    36901 cggatggcat caatttctat ccgcgtaatc ggctgtttgt aggcaataat ggacaaggtc
    36961 tcaagggcag cccgagacaa gctctggttg ataggcgcct tagagtattc cttcaaaatc
    37021 tctgcaaatt gaggcttggt caccaatcta taagcaccac ttgtctcaat caaagccaaa
    37081 ctggaatctg ggtccttttc atacttctgg gctaattttc ctaaactttg ctggatgcct
    37141 gtcggtggca gagagaggag ttcagctaac tggcggaccc gaatcccatc ttcacccgct
    37201 acaaacaaga gcgcttctat ttttgctaaa gtactcatct ttcctctcta tcaagtctag
    37261 ctttgaggca cttgactttc ttccttcttt tccatgagat agatatctcc aaaactctcc
    37321 tcttgcacga ggatcagctc ctgggttttg attaactcta gggttgccaa aaagagggtg
    37381 atgacctctt ggacattctg ggcttccttg aacaaatcct gcaagcgcaa ttgatctcgt
    37441 ccaatcaagg actctttcac gataatcatc atgtcctcaa tcttatactc atcccgcaag
    37501 atcgtcgtat gattttgtgc aaactcctct tttttcttgg ctaggatatt tgaaaaagcc
    37561 aaaaagaggt caatggtcgt cttgtcatgc acaagctccg catcttcgta aatcaactct
    37621 gtcggcgctt tggaataata ctgggcccgt tcttggtgct tggcttccaa gtgctcaccc
    37681 aagagcttga acttgcgata ttcttcgatt tgagagagga ggtcctgctc caggtcatcc
    37741 cccaagtctg tcacttctgc taccttcgga aggagtttac gactcttaat cagcatgagc
    37801 tgactagcca tgaccatgta ctcacccgtc acttccagac gcatggcctg cagggttgag
    37861 acataggcta gatactgttc gatgacttcc gtaatgggca catcgtagat atccatctgg
    37921 tacttagaaa ccagatgcaa gagcaagtcc aggggtcctt caaaatcttt taatttaata
    37981 tccattatct atatttttct aaggtcagga ctgtttttaa tcctaatttt tttgcaattt
    38041 cgtacaaatc gaccttgttt tctatttgtc ttagaataaa ctgttcacgt aagacttgag
    38101 ctgataagga tggaaaacct ttctccttga caaaagattc taactgacga aaggcccact
    38161 gacgagaata gggtttctct cctctttcaa aaagataggt ctgccccatc aagggttcca
    38221 attctgaaag caaggccgtg ggaatagtga caatcctctg ttgggaagcc ttgctgattc
    38281 gcaacacctg aaaatccaga ttgatgtccg caaccttgat ggctaaaatc tcactgggca
    38341 aaagccccat ttctaggatt aagagcgcta gcaagcggcc ctctggatgg tcgctttcct
    38401 gccaaaaaga gtctaggtat agaatctctg gcttttccgt cttcttttca gcttgtttgg
    38461 ctaattccaa gcggtaaaag ctgtccacct ctcctttttg atagagaaag tatagaaatt
    38521 ggttacaggc cgaaatcttt cgcttctggg cgctgatttt tagattggct agctgggctt
    38581 ggtaaatctt gagactggtc tcagaaatcc gctcacctac catgtctaaa aattgctcca
    38641 aatcatactt ataggactgc ttggaattga cagacaagcc ctgcttttcc tctaaaaagg
    38701 ctgaaatcct gtctctcatt ggcatcgaat ctcatattcc ttactaaagt catgcaagag
    38761 ggcattaacg gccttgagga tggacttgcg cgtaataatc ccttggaaaa taccctctgc
    38821 atccacaacc ggtaagaagg actcatctac tagcttgtgc aagacctccg taatggtgaa
    38881 atcaggcgaa acaaccgcta cgtccgtttt tgtcatatga acgatatccg tatccgccat
    38941 gatttcttgg ctcaagtcat gctccatctg ataagccata atatctctga gtccaatcgt
    39001 cccaacaaac tgtttttcat ctgtcacaac gggaacacgg gtataggtca tctgactgag
    39061 caagagggtc gcatgatccg cattgtgggt atcaatcaac acagctagat ttttagcagg
    39121 ggtcaaaaaa gtttcctcct gccccaacaa gaaagtctca aactccttgg caatcatcgg
    39181 ctaaactcct tggacaaacc tggatacacc tcgtgatctc gtgtcaaaaa gtccactttg
    39241 aagtaactat catcaatctc cacacgagca tagagacatt ctctgatggt acctcgtggt
    39301 tgactgatag aacctggatt tagaaagagg atcttgcctt ccaaccaagc acttggcaca
    39361 tgcaagtgac catagaggca gatagcggcc tcttcctcct gagcccagta gtccaacttt
    39421 tgaaagttga aattgatgtc aaacaagtga ccatgagttt ggataatctt ggtcgaacca
    39481 agctcagtca ccagacgttc tgggtagccg gcgtagaagt ccatgttccc tttaacaacg
    39541 cggatgccct cccaaagtgg agaatccgga cgtagttcag aatcgccgtt atgaaaaacg
    39601 gcatcgactt tgcccacata gcgatcacgg acttcttcca caatcaagct atcgccatgg
    39661 gaatcgctca ttacaatgat ggtttgcttt gccatgatgg aaatacctcc aaaagtttct
    39721 taacggctaa ggcacggtga gattgactat ttttttcttc cagggttaat tcagctgatg
    39781 actcacctgt ctctcctaca aggaagaggg gatcatagcc aaagccattt tcacccttag
    39841 gttcaaagtt aatataacct gaccagtctg cttcaacaac taaactttcc ttatttgggc
    39901 tggctacgac tagggttgtg tggaactgag ccgagcggtc cttgagttca aagaccatgg
    39961 ccaattcgtg caagagtttg gcattatttt cacggtcagt tgctcccaca cctgcgaaac
    40021 gagctgacca gacgcctggt aagccaccaa ggacatcgac tttgagacca gaatcatctg
    40081 ccaaaaccat cttgcccgtt aattgagaaa tggtttctgc cttaaggcgg gcattttctt
    40141 caaaggtcat acctgtttct gctacttcag gcaggtcagg gtagtcatta agattttcca
    40201 catcgtagcc taacttatca aagatagctc ggaattcctt ggttttacct tcgttacgag
    40261 tcgcaatcaa caaggtttct ctgaccttgc ttgtctcaaa gaaatcatga acattgaccc
    40321 cttctttagg caattctaca tacaagagtt gcccattttc aaccaagagc agggccccat
    40381 gacgttgaat aacttccaag tttcgtccca tttcttgatt aagcatgtct accacaaagg
    40441 agaacaaacg gtaggtagaa ccatagcgta aaacagtaac tgaaagcggg aaaccatact
    40501 cttcatctcc aaatattttg gagaattcaa acagaggaaa atctgtctta tagtcgctca
    40561 aactgttaac gccaccaaaa atactataag acccaacata ccagtcctgg tcatccttat
    40621 attcataaat tttatttgtc ataattctac atgctccaca tgaatctctt tttccagcca
    40681 ttcttcacca atttgtgcaa aactttggct actggctgtt gtgtaaaaac ggtgatggag
    40741 tggtccagca tcgcgaccac gattgatttc aaaataattg agtaagactg agatatcccg
    40801 tacgcactct gccccactat cgatgagctg aacctttggc cccatcacat tttggataat
    40861 agggcgaagg agtggataat gagtacagcc caaaatcagg ctatccacct ttccaaccaa
    40921 gggacgcagg gtttcataga ccaccttctt ggtaacactg gttgacaggg cacctgactc
    40981 aaccaaggga gcaaacttgg gacaggccaa gctctccacc tgtaagtcgg gatccagatc
    41041 atggattttc tgacggtata tgtctgattg taccgtcatg ggcgttccaa tcactccgat
    41101 tttcccacct tgactggact tgatggctgc cgaagctcct ggcaaaatta cacccaagac
    41161 aggaatatct agttgagcct tgatttcttc ccagacgacc gcagtcgcag tgttacaagc
    41221 aatgacaatc attttgacat ccttggtcaa gagaaagttg accagctgcc aagtatattc
    41281 acgaatttgc tcagcaggac gggggccata gggcgcccgc gccgaatctc caatatagac
    41341 gatttcttca tggggaagct ggcgcatgag ctcgcgcaca acggtcaagc ccccgacacc
    41401 cgaatccaaa aaaccaattg gtcgattatc catacagtct tctttctagt cttttttctg
    41461 attgatcgtt cattatgatt ccttgtactg aacgaactga ccgacagctt gatagaatgt
    41521 caactacctc tctcttaatc ataatcaaat atcaatagaa tgcaaggaaa aagtctcatc
    41581 cctaaaccat aaccaacata gtgagaagtc tggaactttc atcccagact tttccttatt
    41641 tattttttct ttttattgtt agcaagggct gccttttgtt ggcggatgat ttggtggtaa
    41701 acttgttgta ccttagcttc gcttggtttt tgaccatttg cactcaaaag agtacgaact
    41761 gcttcagcat tcaaacgtgg gttgtcagca aattcttttt cgatttgctt acgaaccaag
    41821 tacattcctc caagagctcc tcctagaaaa gctagcacaa tcaatacaat tgctaaaagt
    41881 aaatccatca tttttctcct gtttcttttt gaatcccttt cattatacca caaactagcc
    41941 accctgacca gtttgttcta cactttcaag gatggaatag acagcaaaaa gaaccctgct
    42001 tttctgaaaa agaggtctcc ttgctaagtt taatttacat aaatagccag tgtttgatag
    42061 ggttttagta gaattttctc agacacttct gcatcttcat agtttgaaat caaaatctgt
    42121 ccattttggt agactgctgg caagtcgatt tccacttctt tagcataaaa gttattgagc
    42181 actagtaact tttgatcctc aaactggcgt tcaaaagcgt agacttgttt gctatcttca
    42241 aaggctggtt tgtaacttcc ttctgaaatg attggcattt ccttacgcag tcgaatcaag
    42301 tcttgataga aggtaaaaat cggaccctgg atttcatttt ctacattgat gtctttatag
    42361 gatttaccag ctttcaacca aggagtgcct gttgaaaatc ctgcattttc cgaagcatcc
    42421 cactgcatgg gaatgcgtga attatcacgc gacttagctt gaataatctg gaaggcttct
    42481 tgctgactct ttccttcttc taggagcatc tgataggcat taagcgattc gacatccacg
    42541 taatcagcca tagaatcata gtctgggtca atcatcccga tttcctcacc catgtagata
    42601 taaggtgtcc cacgtgacag gtgaatgctg gctgctagca tagtggctcc ttccttgcgg
    42661 aagttttgaa tatcgacaaa acggttcaag gcacgtggtt gatcgtgatt gttccaaaag
    42721 agggcactcc aaccgtcttt atcactcatt tccttacccc aactatggta aagactcttc
    42781 aactcttcaa aatcaaaggg agccaaggtc cacttttgtc catccttata gtccaccttg
    42841 aggtgatgaa aattaaaggt catggataat tcctgacgat caggcgacga atagaggaca
    42901 cagttttcca tggtggtaga agacatttcc ccaactgtca taaagctatc gtcagatcca
    42961 aaagtggctt ggttcatcat acgcaaatag ttatgaacga tgggtttgtc tgtataagct
    43021 ggcttccctt cattttcagg acagtccact gaaacctcgt ccttaccgat caaattgatc
    43081 acatcaaatc gaaaaccttt gacacccttg tcgcgccaga aattaacaac cttgaaaagc
    43141 tccttacgga cattggaatt gcgccagtta aggtcagcct gggtctcatc aaataggtga
    43201 agatagtatt tcccagtatc cccgaaaggc gcccatgcag aaccaccaaa cttagactgc
    43261 caatctgttg gttggtcttg gatgaagaaa aagtcttgat aatacttatc accagctagg
    43321 gctttctgaa accattcatg ctctgtcgaa caatgattaa gtaccatgtc cagcataaag
    43381 tcaatcttgt gctctttacc gacacacacc atttcctcaa aatcagccat atcaccaaaa
    43441 agaggatcca ctgccatata atctgaaata tcgtaaccat tatcccgttg agggcttgga
    43501 tagaatggat tgagccagac catatccaca cctaatttgg ctaaataggg aattttttcg
    43561 ataatcccac ggaaatcccc aataccgttt tcagtggtgt ctttgtaaga ttttggatag
    43621 atttgataga ctacttttcc tttatcaagt gtcatctgtt tctccttttc tgataaaagg
    43681 gaggaagcag tcttccgtcc ctatttgtgc tatttcaatt atactcaatg aaaatcaaag
    43741 aacaaactag gaagctagcc acaggttgct caaaacacta ttttgaggtt gcagatagag
    43801 ctgacgtggt ttgaagagat tttcgaagag tattagattc gtgtagcgac catgagagat
    43861 gctccagctt ggatcgttgt cggataagtt ccgggaatag tcgctgtata agcatcttgg
    43921 ttggtgatga taacaggagt ttctgtcacc agacctgcag ccttaatgac atccatatca
    43981 aaacgaatca gttgctgacc aactgtaacg tgatctcctt ggactacaag actttcaaaa
    44041 cctttgccat caagacctac tgtatccata ccgatgtgga tgagcaattc aactccctcg
    44101 tcagagacaa tgccgatggc atgcttggta gggaaaagaa ccgtcactgt cccattaact
    44161 ggagaggtca actcaccttg gcttggttca atgaccagac cttgccccat gacacctgat
    44221 gcaaaaatag gatccgtcgc ttgactcaat tctttcactt ggccagttag tgggctgata
    44281 atttctaccg aagtaagttc tactggttca tggttcacaa attctgcttc ttcttgagca
    44341 acgaattctg cctgcaagtt cgtatcgccc tctgtttttg taaagagacc agccttgcgg
    44401 aagaagaaag tcaagagcat tggaacaaca atcgcaacta gcatagttcc tgcaaatggc
    44461 agcatgtatt gaggttgaat agagagaata cctggcaaac caccgatacc aatagaagcc
    44521 gcagttacat taaaagtaac ggataacatg cctgcaaggg ctgaaccagt catcccagca
    44581 acaaatggat aaatatattt tacgttaacc ccaaaaagag ctggttctgt aacaccgaga
    44641 taggctgaaa tggttgcagg aagtgaaacc tgagcctcac gctcatcatg gcgatgcatg
    44701 aaataatagg caaacacggc tgagccttga gcaatattag aaagagcaat cattggccat
    44761 agggcagtgc caccagcatc cgcaatcaat tgtgtatcaa tggcattggt catatggtgc
    44821 agacctgtga tgacaaatgg agcgtagagg gcaccaaaaa ttgcaccgaa gagccattta
    44881 actggaccag ttaaacctgc caagacaact gatgaaagtc cttgtccaat tgtccaaccg
    44941 attggtccca aaacagtatg agccaaaatc aaggctggaa tcaatgacaa gaaaggtaca
    45001 aaaatcatag aaatgacttc tgggatatgc ttgcgccaga agatttcaag ataagacaga
    45061 ctcaaacctg caagcaaggc tgggataact tgggcttggt aaccgatacg attaacagta
    45121 aaatagccaa aattccaaac ccagtttgcc gcgatatcag ctgctggcgt tgaagcaacc
    45181 gcataggcat tgagcaactg aggcgatacc aaacagattc cgagaacaat tcccaaaatt
    45241 tggctggttc ccatcttacg agaaacagac caagtaatcc ctactggtaa gaactggaag
    45301 atagcttcac caggcaacca aaggaagtga ttaacccctg cccaaaactg agaggattct
    45361 gtgatggtct tgccatccaa catcgaccaa tggacacctt ccaagacatt acggaaaccg
    45421 aggatcaatc ctccgactat caaggctgga ataatcggag taaaaatctc cgccagagtg
    45481 gtcataacac attggaccac gttttgatta ctcttagctg cagacttggc tgcttctttg
    45541 gaaacaccct caatacctga aacggctgta aaatcattat aaaagatggg cacgtcattt
    45601 ccaatgatta cctgaaattg acctgcattt gtaaaagttc ctttaacagc tggaattgac
    45661 tcgatagctt taacattagc cttcttatca tctcctaaaa caaagcgcat ccgtgtcgca
    45721 cagtgagtta cggcagtcac attttctttg cctccaattg cctgaagcag atctttggct
    45781 tcttgttcaa attttcccat ttgattctcc ttatacttgt caaagcaagt ttgatttgat
    45841 aagtatattg taaacgatac caaacttgtc tgcaacttgt ttggtataaa aagggtgttt
    45901 ttttgtaaat tttctagcac ttgtatggta aaatagatac aggtgttcat taaactagac
    45961 tgaaaaccta tttaagcagg caaaatgaag aaataccaac aattatttaa gcaaatccaa
    46021 gaaaccattc aaaacgagac ttacgctgtc ggagatttcc ttcctagcga gcacgacctt
    46081 atggagcaat atcaagtgag tcgtgatacc gtccgaaagg ccctgtctct cctccaagag
    46141 gaaggattga tcaaaaagat aagagggcaa ggttctcaag tcgtcaaaga agaaaccgtc
    46201 aatttccctg tatccaacct aaccagctac caagaactag ttaaagaact tggactgcgc
    46261 tctaaaacca acgtggtcag tctggacaag attattattg ataaaaaatc ctcactgata
    46321 accggtttcc cagagtttcg gatggtttgg aaggtggtcc gccagcgtgt ggtggatgat
    46381 ctggtatccg ttctggatac agactatctg gatatggaac tcatcccaaa tctcactcgc
    46441 caaattgctg agcagtctat ctattcttat atagaaaatg gcctcaaact ccttattgat
    46501 tatgctcaga aggaaatcac cattgaccac tcaagcgacc gagacaagat tctcatggac
    46561 attggcaaag acccttatgt cgtttcgatt aaatcaaaag tctatctcca agacgggcgc
    46621 caatttcagt ttaccgaaag tcgccataag ttagaaaaat ttagatttgt agattttgca
    46681 aaacgcaaga aataaaagac tgagacacca gatctcagcc tttttcttta tcccaaaact
    46741 aattcatcac tgaccagact ttggccacta tttttctgga agagatgcat aaggtcttca
    46801 actgtcagat gctttttctc ttctcccttg acatccacca ctatcttgcc ttgatagagc
    46861 ataatgagac gattgccgta ctcaatcgca tgattcatat catgggtaat catcaaagtc
    46921 gtccactgat ggtactccac aatcttttgc gtcaagtcca tcaccatttg actggttttc
    46981 gggtcaagtg ccgcagtatg ttcatccaaa agcaaaagtt tgagtttcac cagagctgcc
    47041 atgactaggg tcaaagcctg tctttgtcct cctgagagat attgagtatc tacttttaag
    47101 cggttttcaa gaccaatatt caactccttc aaggcctctt ggaactggat tctatccttc
    47161 tccttcacgc cccaaccaag ccctctcttt tgcccacgtc tcaaggcaat agccatattc
    47221 tcctcaatcg tcaaacgaga agctgttccc atcttaggat cttgaaaaac acgggcaata
    47281 tccttggctc tctttctgac actcagatgt ttaatggatt tccctgccag tagaaggtcc
    47341 ccttcgtcca ccgatagatt accagccaag atattcatca aagtggattt tcctgctcca
    47401 tttctaccaa tcacagagat aaaatctccc tcttcaacct ctaaatctaa tcctttgagg
    47461 acatggttct cattgaccgt ccctgcttca aatgtcttgt gaatattttc aagtgttaac
    47521 aaacttgcca taactttctc ctcctattca tttctcaatt tcagaccacg aatctttaat
    47581 ctcttttgca attctggtgc aaataaaacc aaagcgagca agattgcatt aaagagacgt
    47641 accaagtttt gatctagatt tggaatttca tagatattta aaataatcaa acggtaaaca
    47701 atagcaccga ttccgatgga taataagtgg cctccaatgg tcaagtcgtg tatcaagact
    47761 tccgagctca aaccaacaac aatggttcct gtcccagaag tcacatctga aaatccatca
    47821 ttttgggcaa acaaggaacc acatagggca atcaaaccgt ttgaaatcat gtaaccaaca
    47881 atcttcatgg tgtttacatt gactccattg gcctcactca tcgggatatt gtccccagtc
    47941 gaacgcaaga ccaaaccaat ctctgttttc atcaaaaggg tcaagaccaa acaagtaaga
    48001 gacagactaa actaagtgag aaaacagctc cttcatttgt cagacccaag ctcgccaact
    48061 gtttaaagac ggttgcagaa tctcccaagg aaagattggg tacactgccc ataattttaa
    48121 tattgattga atagagccct gtcaaggtca caatccctgt caagagagct gggattttca
    48181 tattggtgtg gagcattcct gatacaagac ctgctaccat acctgccacc aaagcaagta
    48241 aagtcgcaag ccaaggattt gcccctgcct gtatctgtga tacaacgact gctgccccca
    48301 gaggaaaggc tccctcagca gtcatatccg caatattcaa aatacggaaa gtcaagtaga
    48361 ccccaattgc cataatcgac cacaacaaac cttctgataa actagataac acaaaattca
    48421 tcttaatcct ccttattcct tgccttctaa cttactaata tcaattccca atgcatctgc
    48481 catttcttga ttggtatgca attccagttt ttcaggcaac tcaactgcta tattttctgg
    48541 tttctcacct tttaaaacac gaatcagcat gcgagctgtc tgccgtccca attcttcata
    48601 attggttccg tagttataca agccaccaac agcaatcatt tctgttgaac caccgaatac
    48661 tggaaccttg tgtttaatag aaacctgctt aactgtttcc atggttgacg aaatgatatt
    48721 atcagttggg acaaaaacca tatccacctc tgccatcaaa ctctctgctg ccgccttgac
    48781 gttattactg tccaagattg ttttttcaac aacggtaaag cctttttctt tcagaagtcg
    48841 cttagcttca tccttttaaa caaccgaatt gggctcgctc tgagtataga ggattccaat
    48901 cgttttagcc tttggcaaca ctttctttat caaattgatt tgggttgaaa tggcatctga
    48961 tgactgatcg cttgtcccag ttacattgcc cccaggatgt tctcttgact caaccaactt
    49021 ggcactgact gggtctgtta cagctgaaaa gataactggt gtcgtttgcg tcgtattggc
    49081 caagctctga gcagaaggcc ttgcgatggc tagaacgaca tcgctggatt ctgctagttg
    49141 ctgggaaatc gtttttagat ttctttgttc tccctgtgca ttttgcaaat caatctcaat
    49201 attttccccc tcaacatagc cttgtttggc cagctcatcc acaaatcctt ctctagtagc
    49261 gtctaaggac tggtgggtaa taaactgcga aataccgata cgaaagacat ctttttctta
    49321 tctgccttca actgatgcaa actgatcaga gaagtcaaga ggagccccac taccaagagg
    49381 gggctagtga ttttcgaaca actttcataa tgaaactcct tctcagaaaa gataaaacaa
    49441 aaaaccgcct agatactatc taaacggata cttgaaataa cctaacaagt tacaacttag
    49501 ctagtccatt tagatattca tctatatgga ccacaatcaa aaatcttagc cacatagata
    49561 caaacaaatt gcttgaactg tttgcatcca tggtgacatg tctacaaaca ctatctaaag
    49621 tagctaaagt aaaagttttg attcatagtt acggcttgtc tcttattcat ttctttttct
    49681 gctttctttt ttgatgcttc ctatcctacc acctttttca tcacctgtca ataatatttc
    49741 agaatttttt aaaatttttc gaaaattctt tcaggaagct ttcaaagttt ttcaaatcag
    49801 tccaacaaaa aaagttttat aattcccata aaaat
//
LOCUS       DBEROT010000010        48274 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.10, whole genome shotgun sequence.
ACCESSION   DBEROT010000010 DBEROT010000000
VERSION     DBEROT010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.10"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            110..386
                     /locus_tag="ACL8CG_000696"
                     /pseudo
     CDS             110..386
                     /locus_tag="ACL8CG_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(511..759)
                     /locus_tag="ACL8CG_000697"
     CDS             complement(511..759)
                     /locus_tag="ACL8CG_000697"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343335.1"
                     /translation="MASTSLQAPAKICFILIKPYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(707..1789)
                     /locus_tag="ACL8CG_000698"
     CDS             complement(707..1789)
                     /locus_tag="ACL8CG_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS1343336.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1915..2697)
                     /gene="gatD"
                     /locus_tag="ACL8CG_000699"
     CDS             complement(1915..2697)
                     /gene="gatD"
                     /locus_tag="ACL8CG_000699"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGS1343337.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2697..4040)
                     /gene="murT"
                     /locus_tag="ACL8CG_000700"
     CDS             complement(2697..4040)
                     /gene="murT"
                     /locus_tag="ACL8CG_000700"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGS1343338.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4139..5455)
                     /locus_tag="ACL8CG_000701"
     CDS             complement(4139..5455)
                     /locus_tag="ACL8CG_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGS1343339.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVTAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5648..6874
                     /locus_tag="ACL8CG_000702"
     CDS             5648..6874
                     /locus_tag="ACL8CG_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGS1343340.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKALT"
     gene            7073..8647
                     /locus_tag="ACL8CG_000703"
     CDS             7073..8647
                     /locus_tag="ACL8CG_000703"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1343341.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8911..9699
                     /gene="codY"
                     /locus_tag="ACL8CG_000704"
     CDS             8911..9699
                     /gene="codY"
                     /locus_tag="ACL8CG_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGS1343342.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9699..10274
                     /locus_tag="ACL8CG_000705"
     CDS             9699..10274
                     /locus_tag="ACL8CG_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS1343343.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10356..10441
                     /locus_tag="ACL8CG_000706"
     tRNA            10356..10441
                     /locus_tag="ACL8CG_000706"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10390..10392,aa:Leu,seq:aag)
     gene            10724..11854
                     /locus_tag="ACL8CG_000707"
     CDS             10724..11854
                     /locus_tag="ACL8CG_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343344.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12355..13113
                     /locus_tag="ACL8CG_000708"
     CDS             12355..13113
                     /locus_tag="ACL8CG_000708"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1343345.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13200..13712
                     /locus_tag="ACL8CG_000709"
     CDS             13200..13712
                     /locus_tag="ACL8CG_000709"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGS1343346.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13894..14838
                     /gene="metA"
                     /locus_tag="ACL8CG_000710"
     CDS             13894..14838
                     /gene="metA"
                     /locus_tag="ACL8CG_000710"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGS1343347.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14847..15524
                     /locus_tag="ACL8CG_000711"
     CDS             14847..15524
                     /locus_tag="ACL8CG_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS1343348.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15622..16380
                     /gene="tpiA"
                     /locus_tag="ACL8CG_000712"
     CDS             15622..16380
                     /gene="tpiA"
                     /locus_tag="ACL8CG_000712"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGS1343349.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16418..17923
                     /gene="lytC"
                     /locus_tag="ACL8CG_000713"
     CDS             16418..17923
                     /gene="lytC"
                     /locus_tag="ACL8CG_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGS1343350.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGVRYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELKRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18421..18939
                     /locus_tag="ACL8CG_000714"
     CDS             18421..18939
                     /locus_tag="ACL8CG_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGS1343351.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            19069..19575
                     /locus_tag="ACL8CG_000715"
     CDS             19069..19575
                     /locus_tag="ACL8CG_000715"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGS1343352.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19575..19745
                     /locus_tag="ACL8CG_000716"
     CDS             19575..19745
                     /locus_tag="ACL8CG_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343353.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19777..21009
                     /gene="clpX"
                     /locus_tag="ACL8CG_000717"
     CDS             19777..21009
                     /gene="clpX"
                     /locus_tag="ACL8CG_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGS1343354.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRMGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21018..21605
                     /gene="yihA"
                     /locus_tag="ACL8CG_000718"
     CDS             21018..21605
                     /gene="yihA"
                     /locus_tag="ACL8CG_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGS1343355.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21616..21996
                     /locus_tag="ACL8CG_000719"
     CDS             21616..21996
                     /locus_tag="ACL8CG_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGS1343356.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22048..22938
                     /gene="rapZ"
                     /locus_tag="ACL8CG_000720"
     CDS             22048..22938
                     /gene="rapZ"
                     /locus_tag="ACL8CG_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGS1343357.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22935..23912
                     /locus_tag="ACL8CG_000721"
     CDS             22935..23912
                     /locus_tag="ACL8CG_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGS1343358.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23909..24820
                     /gene="whiA"
                     /locus_tag="ACL8CG_000722"
     CDS             23909..24820
                     /gene="whiA"
                     /locus_tag="ACL8CG_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGS1343359.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24908..26035)
                     /locus_tag="ACL8CG_000723"
     CDS             complement(24908..26035)
                     /locus_tag="ACL8CG_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1343360.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(26177..26557)
                     /locus_tag="ACL8CG_000724"
     CDS             complement(26177..26557)
                     /locus_tag="ACL8CG_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGS1343361.1"
                     /translation="MTIEELVDSHGVTLAYFDNELWQKPGVYIKEISIIFINRELSED
                     AKKRVIYHELGHLEHSTALYQNNHTRCENEANRHMIHKLLEEELALSDDHQSFNYIQF
                     MQKHKLRTVTDELMVIDEYYELIG"
     gene            complement(26780..27874)
                     /locus_tag="ACL8CG_000725"
     CDS             complement(26780..27874)
                     /locus_tag="ACL8CG_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343362.1"
                     /translation="MTITEQDALLFNTLFENIYHQLPSVDSSKDYWFVRAQKGQFYKS
                     FQTGGYIAIGWNYITLDDLKNLDEDAIKGKIKEFDSRIEKPGSAYNQMMKFAYSLKIG
                     DIVIVPSESPNDFLVGEITSRPYTESESNIESASNVCPFNKRMNVHWFGVIPNRDIDP
                     KLYKLVYSGHTITDANAYKKFINRGLYDAYIDHDHMSITFKVQEENNIDAFEYSTFLH
                     TVLQMVNVVKESDELKDEKVVLRTNVQSKGPIELLGHPEILIPVLVFIIILTGGIAFR
                     NLIKRNGANFEVDSKLGKFKAQLNSDGDEAIKKAQANKINAEAIALLIDKGMSPQFKG
                     ATSQLDIKAPEVATRILQDELLESPEKVEE"
     gene            complement(27876..28229)
                     /locus_tag="ACL8CG_000726"
     CDS             complement(27876..28229)
                     /locus_tag="ACL8CG_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1343363.1"
                     /translation="MFSTLEKIKELAKKRGIPLTKLEESLGYSTNYFYTLKTKTPNSE
                     RLQQIADYFNVSTDYLLGRTDNPAIAGDDTISGYTSDDLRKMAENAKTFDGKPLTEED
                     IDAIQNIIEIYLRGR"
     gene            complement(28627..28719)
                     /locus_tag="ACL8CG_000727"
     CDS             complement(28627..28719)
                     /locus_tag="ACL8CG_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGS1343364.1"
                     /translation="MMELILKTIIGPIVVGVVLRLADKWLNKDK"
     gene            complement(28942..29031)
                     /locus_tag="ACL8CG_000728"
     CDS             complement(28942..29031)
                     /locus_tag="ACL8CG_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I addiction module toxin, Fst family"
                     /protein_id="HGS1343365.1"
                     /translation="MVDYIFTNIILPLVVGIVLIVIEKWLNKK"
     gene            complement(29255..29494)
                     /locus_tag="ACL8CG_000729"
     CDS             complement(29255..29494)
                     /locus_tag="ACL8CG_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343366.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            29559..29750
                     /locus_tag="ACL8CG_000730"
     CDS             29559..29750
                     /locus_tag="ACL8CG_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGS1343367.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            complement(29933..30124)
                     /locus_tag="ACL8CG_000731"
     CDS             complement(29933..30124)
                     /locus_tag="ACL8CG_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343368.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTVELLEKYHEWLHS"
     gene            30243..30386
                     /locus_tag="ACL8CG_000732"
     CDS             30243..30386
                     /locus_tag="ACL8CG_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343369.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            30465..30737
                     /locus_tag="ACL8CG_000733"
     CDS             30465..30737
                     /locus_tag="ACL8CG_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343370.1"
                     /translation="MEVVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            30734..30928
                     /locus_tag="ACL8CG_000734"
     CDS             30734..30928
                     /locus_tag="ACL8CG_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343371.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            30925..31116
                     /locus_tag="ACL8CG_000735"
     CDS             30925..31116
                     /locus_tag="ACL8CG_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343372.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            31128..31469
                     /locus_tag="ACL8CG_000736"
     CDS             31128..31469
                     /locus_tag="ACL8CG_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343373.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYFNHTQALTELVDWKNDTRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            31470..31700
                     /locus_tag="ACL8CG_000737"
     CDS             31470..31700
                     /locus_tag="ACL8CG_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343374.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            31714..32436
                     /locus_tag="ACL8CG_000738"
     CDS             31714..32436
                     /locus_tag="ACL8CG_000738"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HGS1343375.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGVSLTEKQIKSYRRNNNLHSGLTG
                     RFEKDQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            32429..32911
                     /locus_tag="ACL8CG_000739"
     CDS             32429..32911
                     /locus_tag="ACL8CG_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HGS1343376.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQAAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNENDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELIRTEKLVIK
                     "
     gene            32920..33270
                     /locus_tag="ACL8CG_000740"
     CDS             32920..33270
                     /locus_tag="ACL8CG_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343377.1"
                     /translation="MNKTRVTDSLAVVIGLESIEVLVTEGFLFDVAIRFVKVDETNLD
                     QGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQNWFN
                     TALYPGVLTEKVGV"
     gene            33270..33755
                     /locus_tag="ACL8CG_000741"
     CDS             33270..33755
                     /locus_tag="ACL8CG_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343378.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNEKSKDNSVAETIAYIQLCYPEAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            33718..34911
                     /locus_tag="ACL8CG_000742"
     CDS             33718..34911
                     /locus_tag="ACL8CG_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS1343379.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            34930..35247
                     /locus_tag="ACL8CG_000743"
     CDS             34930..35247
                     /locus_tag="ACL8CG_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343380.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            35247..36023
                     /locus_tag="ACL8CG_000744"
     CDS             35247..36023
                     /locus_tag="ACL8CG_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1343381.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYVNH
                     VDDKAILKILATIRGAVEPAKTEKTKEAPKKEVASDDELF"
     gene            36043..36546
                     /locus_tag="ACL8CG_000745"
     CDS             36043..36546
                     /locus_tag="ACL8CG_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343382.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKDLNWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DDDDLPF"
     gene            36719..37540
                     /locus_tag="ACL8CG_000746"
     CDS             36719..37540
                     /locus_tag="ACL8CG_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HGS1343383.1"
                     /translation="MSSMKEYALQYQKLGFSVIPINPKNKMPLIDFADKPAMTPSEIE
                     NFWDGYPNANIALKITNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKDLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            37543..38886
                     /locus_tag="ACL8CG_000747"
     CDS             37543..38886
                     /locus_tag="ACL8CG_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HGS1343384.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQKEYLKDKTGER
                     RFLPIMADSKQQKKHPMEIDPDTIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKNTKGFVRVKNSEKTNR"
     gene            39179..39331
                     /locus_tag="ACL8CG_000748"
     CDS             39179..39331
                     /locus_tag="ACL8CG_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343385.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KMEEME"
     gene            39331..39669
                     /locus_tag="ACL8CG_000749"
     CDS             39331..39669
                     /locus_tag="ACL8CG_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343386.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNLGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            39820..40134
                     /locus_tag="ACL8CG_000750"
     CDS             39820..40134
                     /locus_tag="ACL8CG_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343387.1"
                     /translation="MEELKRKVNTVYNWTVEDGKPQPPKQDLPQVVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPSMAQVVIAVYLIYR
                     GN"
     gene            40136..40663
                     /locus_tag="ACL8CG_000751"
     CDS             40136..40663
                     /locus_tag="ACL8CG_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HGS1343388.1"
                     /translation="MNKQELIKKLEERRTITGNFQGYVVWWKDVKEIFEQLGEPQPVK
                     VPQFVADWIRKCKMFKHFAVSLSFALQPIVWEENGLSHECIEWLMDANNQELFALAWL
                     NGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELEDANF
                     GWVFDCEGIDIEEVE"
     gene            40725..41042
                     /locus_tag="ACL8CG_000752"
     CDS             40725..41042
                     /locus_tag="ACL8CG_000752"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGS1343389.1"
                     /translation="MRYFKILCIVLFASLLVACHQISSGTVVDKYIDEPHTTFIPVIN
                     GKSSVLVPTRTKRKYILVVSGYAGNKQVEERFEVTANEYKHYEIGNTFIQDAVLENKE
                     EDK"
     gene            41160..41582
                     /locus_tag="ACL8CG_000753"
     CDS             41160..41582
                     /locus_tag="ACL8CG_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HGS1343390.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWIDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRLINKLKNPKSRSILRVTYITK
                     MYVDDICDKMEISRTTFYTWRNMAISELNEVLERMELN"
     gene            41668..41750
                     /locus_tag="ACL8CG_000754"
     tRNA            41668..41750
                     /locus_tag="ACL8CG_000754"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41699..41701,aa:Tyr,seq:gta)
     gene            42852..43364
                     /locus_tag="ACL8CG_000755"
     CDS             42852..43364
                     /locus_tag="ACL8CG_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0051276 - chromosome organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HGS1343391.1"
                     /translation="MAFFDCLKGGDGKLNERQRRFADEYIISGNAYQSALRAGYSEKY
                     AKARSSELLDNVGISDYIKNRMEELQDEKILTQKQILVMLSEIASGQAKETIVVTTKV
                     AELMTDPVTGKSVKVYNEIPQLVEYPTKNSDRNKALELLGKRHKMWTDKVEADVSGTV
                     VFANESDISD"
     gene            43342..44640
                     /locus_tag="ACL8CG_000756"
     CDS             43342..44640
                     /locus_tag="ACL8CG_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HGS1343392.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETSRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIVADSAELRL
                     IEELRSEHGITRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            44652..46121
                     /locus_tag="ACL8CG_000757"
     CDS             44652..46121
                     /locus_tag="ACL8CG_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGS1343393.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSRLKNLKSYYM
                     GDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADSDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQNEQVTPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            46030..47667
                     /locus_tag="ACL8CG_000758"
     CDS             46030..47667
                     /locus_tag="ACL8CG_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HGS1343394.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLMSLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVAYDEDADYSKLKRRARNPVTGKTELVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKMK
                     QKLVAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            47669..47878
                     /locus_tag="ACL8CG_000759"
     CDS             47669..47878
                     /locus_tag="ACL8CG_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343395.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSIDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            47875..>48274
                     /locus_tag="ACL8CG_000760"
     CDS             47875..>48274
                     /locus_tag="ACL8CG_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HGS1343396.1"
                     /translation="MIDIALAIAKKAHAGQVDKADVDYIQHPLYVASQVKTEQEKAVA
                     LLHDVIEDSDITAADLLASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIY"
BASE COUNT        15285 a         8458 c        10640 g        13891 t
ORIGIN      
        1 tgttcaagaa ttaatgactg agttttcgtt agttcttctt ctaaaagcca ttaaactagc
       61 tcgttcgacc tactactatc acttgaaaca gctagacaaa acagataagg accaaggctg
      121 gcaatatcaa cacgattctt atcatcggtt tctagagagt aagggaattc aagcatccat
      181 gtcacgtaag ggcaacagcc cagacaacgg tatgatggag tccttctttg ggattctgaa
      241 atcggaaatg ttttaagtcg tttcagtcgc ttaagcaatt ggaacaagct attgtagact
      301 atattgatta ctacaacaac aaacgaatta aggtaaaact aaaaggactt agtcctgtgc
      361 agtacagaac taaatccttc ggataaatta attgtctaac tgtttggggt cagtacacaa
      421 tacctgatag tatgcgtttt attgtgggaa gattttcctc attttctagt gaaattgaac
      481 tttttctaac atcttttgat agatgacttc ttaatcaatt atcatttcca ttgttgtttc
      541 ttggggtttc atcccttgtc tttgataaaa gcggagagca ccctcgttat cattccagac
      601 acttagggtt agattattgc agccaatttc tttagcataa tagcagaaaa atgacaataa
      661 aatagcccct agatattttg aaaggaaagc ataggggcta tatggtttaa tcaaaataaa
      721 gcaaatcttt gctggtgctt gtaaagaggt cgaagccatc cttggtaaca acaccgcagt
      781 cttcaatacg aacaccgact ttaccaggga tatagatacc tggttcaaca gagaagcaca
      841 tgccttcttc gatgaccatg tcgtttcctt ccatgataga tgggaattca tggacatcca
      901 taccgatacc atgcccgaga cggtggttga agtactcacc ataaccagct ttttcgatga
      961 cctcacgggc agcgcggtcc acttcatgag cagtcacacc tggcttgata aagtcaagag
     1021 cagcttgttg ggcttcaaga gtcaagttgt aaatatcttt cttgaattgg tctggtttgc
     1081 cgacagcgac tgtacgagtc atatctgacg catagccatt gaccagaaca cccaggtcaa
     1141 agaggagaag agcatcattt tcaaccttat tagctgctgg aatgccgtgt ggattcgcag
     1201 cattatcacc agtcaagacc atggtatcaa agctcatttc gtaaccttca cgtttcatgg
     1261 caaagtcaat ttgtgcgatg atatctgtct cagtcttatc aagagaaata ttatcaaaac
     1321 caacatgaac agccttgtca gcataaagac ctgcaaccat cattttttgc acttcatcag
     1381 ctgatttgat gaggcgcatg cgttggatac gaggagtgag gttgtcaaac tcagcagtct
     1441 caaaaactgt tttcaaacca tggtatttgg tcaagatgag attgtcaaac tcaacagcga
     1501 cacgtttgaa gtcaagttgt ggaagagcat gtttgatttt ttgccatgga ttttcagaat
     1561 cgacatagcc cactactggg aaggaaacgg tgctacttgc acgttctact tcaagagctg
     1621 ggacaaagag gagaggttcc tgatccgcta ggacaaagag gaacatttgg cgttcatggg
     1681 gatcactgta aaaaccagtg aggtaattga ttgtgacggg gtcagatacg acagcgacgt
     1741 ctagtttttc tgattcaaga tatgttagga tttgttgtaa tttagacata tgctaccttc
     1801 tttctacccc tctattttgg caaaaaatga gagaaaatgc aagggagaag ggtaaaagaa
     1861 aagacaaaaa actccgacaa gataacggag ttctttgata tcattttcct ttgtttaaga
     1921 aaagtcagcc ttgcttttga cgtcactgta ctcttcagcg atttcttggc tgaggatatc
     1981 ctcataggca gggagttgga tatcctgacc atatttcttc ttgagggcag tagtaactag
     2041 gcgataagcc agattggcat tacgagagag gataggtccg tggaagtagg aaccaaagac
     2101 attcttataa tgaacccctt caccgacctt ttcttcgttg tttccatttc catagacaac
     2161 ctgtcccagc ggtttttggt catcagagag gaaggtacgg ccttggtgat tttcaaatcc
     2221 atagtaggtt tcatcgaaat cttcattgtg aatcttgatg tcaccgataa aacggttatt
     2281 ggtctggttg agcgtgtagt gtcccatgac ccctagccct tcgatacgtt ttcctgaagc
     2341 ttcaacataa tattgaccca atagttggaa accaccgcag atagccagaa ctacaccgtc
     2401 gttttggatg tagttgtcaa tgctctcttt tttagcaggt aggtcgtctg caatgatact
     2461 ttgttcaaag tcttgaccac caccgaaaaa ggcgatgtcg tagtgatttt catcaaagtc
     2521 atcatggaga gaaacgatgt caacggtcac atgggctccc agtttttcag ccacatactt
     2581 gagcatgagg atgtttccat tgtccccgta ggtattcatg agatttccgt agaggtgggc
     2641 aatgttgagc tgataggggt aattgccatc ttttgaggaa agtgaagtat aaaccattag
     2701 ttcatctcct ttctaacaat ctgacgacta gccagcagtt cacgaaattc cagcatggca
     2761 gtataagttg ccagaatata ggcatgcttg cagtcttgat tctcaatggt cttgagaact
     2821 tgctccagat tactcgtttc agtgattttc tcagctggat agccagtcac tcggaggcga
     2881 cgagcgattt cagaatgacg aacaccgcca gcgttgattt caggaatgtc catgtcagtg
     2941 atttgttcaa agtctgcatc ccagatccag ctagtgtcaa ttccatctgc atagttggca
     3001 ttaaggagga cagataggct aaatggataa ggtgctagtt tgatcatttc gatagcttgg
     3061 gttgcaccga ctggattttt aatcaagaca agggtacatt ccttgtcacc gatatgaaag
     3121 gtttcttggc gtccaaagac agcacggctc ttgtcaaatc cctgtttgat gagttgcgaa
     3181 tcggcaccta ggaaacgggc gatggccaca gcagctaggg cgttatagat attatagagc
     3241 ccgccgattt ggataccgta ttcttggccg tctatgacaa agcgagagcg attgttggtc
     3301 aactcaacca gttttgtcaa acgatagtcg agatcaggac gtttgcatcc acaaccttca
     3361 cagatatagg cacccaagtt tgcataggta ttatgctcat atttgaggat gccttggcag
     3421 tcaggacaga gaatcccttc ggtattgtag tgagccagtt gggctggtcc tttttccaag
     3481 tcaaaaccaa aatactctat agggtttgga atagttggct tgtagaaaag tggactgtct
     3541 ccgttaagga gaacagtagc agttggaact ttccgaatgg catccaatat catgttatag
     3601 gtagtataga tttcaccgaa acggtccatc tggtcacgga agatattagt aatgacaaaa
     3661 agactaggct ggatatagtc acagatacga gatagactgg cttcgtcaat ttcgaggacg
     3721 gcaatatttt tcccagtttt tgaagatttg gctgttagga aggttgttgc aatccctgta
     3781 atcatgttgg caccgcttgg gttggttaga acttgaccat aaacctcttt taaaatgccg
     3841 acagtgaggg cagttgtcag ggtttttcca tttgttccag tgacaacgac aatctcgtag
     3901 ttcttagcta ggttttgtaa aatatcttta tcaaattgaa gggcgacttt acctgggagc
     3961 gtacttccac ggccaagacg gcttaaaatg aagtgggaag aacgcccagc aagaaggccc
     4021 aaagtagttt ttaagttcat gtttctatta tatcataaaa gaggagaaag acagatttga
     4081 gattccgcag aagtaaaaac agcccaaaga gggctgttcg atacgattaa atctcaactt
     4141 aaatcgcaaa caagtcattc aagttctcag ccaaggttgg gtgagtgaag atttgttttg
     4201 tgaagtaagt gtaaggaatc ttgttgtcca tagcaacagt gatgatgttg atgatttctt
     4261 gagaaccttc tgagaagatg cttgctccaa gaatttcttt tgtttcagta ttgacaacag
     4321 ctttgaaggc accgcgaagg tctccattta cgtgaccacg aggcattgct gtaacgggga
     4381 tttccttaac agcgtatgga agtttcaaat cagctgcttg gctttcagtc aaaccaactt
     4441 gtgaaagtgc aggtgtgatg aacatagtat ttggcacatt gagacggtct tcaagtgtgt
     4501 agctgccatc tccagcaagg tagctgtaaa caacacggaa gtcatcaagt gaaatgtaag
     4561 taaattgaag gccaccgttg acatctccaa ctgcaaagac accaggaacg tttgtttgac
     4621 agtgtttgtc tactttaata gcaccacgtt cagttagttc aatatctgta ttttcaagtt
     4681 gaagtggttc tacatttggt ttgcgtccag ttgcgtagag aagggcgtcg aaacggtaag
     4741 tttcgtcttc agttacgaca agcacttggt caccatcgtt tttgatttca gtagtatgga
     4801 tattttgaag caattcaatg ccatcttctt ccatgtattg tttagcaaga gctgcgatgg
     4861 aaggttctgc acgaggtagg aatgtatcca aggcatctag gactgtgacc ttgcttccaa
     4921 gtttgttgta aaggccggca aattcaagac cgatatttcc gccaccaagg attccaagtt
     4981 tttcaggtaa tttgtccaag ctttggatac ctgttgagtc aaagatgttt ttgcttgtag
     5041 caagtccagg gattggcaag acgtttgaaa cagcaccagt gttgatgacg attgtttcag
     5101 cagtcagttc tttcttttca tcaccagctt ggatttcgat gactttattt gaaaggaagt
     5161 gagcttccgc atcaaagata tctacgcctg taccagcaac agtcgcatag tttttaccgt
     5221 tgaggcgacc agtgatcgtg tttttagtag caatgacttc ttcaaaagac aagtcctttt
     5281 cagcagcaac tagcaaggtt ttagttggga tacaaccaat gttgatacaa gttccaccgt
     5341 acatagcctt gctgcgttca acgagggcaa cttttttgcc agctgaagcc aatttacctg
     5401 ctagtgtttt accagcttta ccaaatccaa taacaattaa atcgtatgtt aacatttatc
     5461 ttcctcctat tcgaatttca ttctagcaca agaaaaaaac ttttgcacaa ttctgctacg
     5521 gaaaagacag aaaaagataa aaacgctttc cagacaaaaa actagtaatt ttttgacaag
     5581 cttgataaac taaaatccta tctattttta tataagatag aataaatgtt cgaaaatagg
     5641 aggttttatg aaatcgaatc gttatattat tgcctttgct ggggtcattt tacacttaat
     5701 gctgggttcg acttatgctt ggagtgttta tcgtaaccct attattgaaa aaacgggatg
     5761 ggatcaggct tctgttgcct tcgcctttag tctagcaatc ttttgtttgg gcttatcggc
     5821 tgcatttatg gggcgtttgg tagaaaaatt tggtccgaaa gtcatgggaa gtctatctgc
     5881 ttttctatac gcaggtggaa atatcttaac aggatttgca atagaccgtc aggagctgtg
     5941 gttgttgtat ctcgcttatg gcattttagg tgggcttggt ttgggagcag gctatattac
     6001 ccctgtgtcg acgattataa aatggtttcc tgataaacgt ggtctcgcaa caggtttagc
     6061 gattatgggg tttggttttg cttctttatt gactagtccc atagcgcaac acctcatcgc
     6121 aggggtaggg cttgtagaaa ctttttatat tttaggagca agttacttta ttatcatgct
     6181 cctagcttca caattcatta agcgtccaaa tgagcaagag cttgcaattt tatcttcttc
     6241 agggaaagaa aaaacagcct ctttgacgca aggaatggct gcaaatcagg ctctaaaaag
     6301 caatcggttt tatatgcttt ggattatttt ctttatcaac atagcttgtg gtttaggctt
     6361 aatttcagcg gcatcgccaa tggcacagga gatggctggc ttgtctacaa gtcatgcagc
     6421 agtaatggtg ggtgttttgg ggattttcaa tggatttggt cgcttgctct gggcgagttt
     6481 gtctgactat atcggtcgcc ctctaacctt tagtatatta ctgcttgtca atcttttctt
     6541 ttctctctca ctttggctct ttacagattc cgttttattt gtagttgcta tgtctatttt
     6601 gatgacttgc tatggagctg gtttttcttt gattccagct tatctcagtg atatttttgg
     6661 aaccaaggaa ttggccgctc tgcatggtta tattttaaca gcttgggcaa tggctggttt
     6721 agcgggacct attttattag cagagactta taaaatggct cattcgtaca cacaaacctt
     6781 gttcgttttt ctcattttat acagtatcgc cttggctttg tcttattatc taggtcgttc
     6841 aatcaaaaaa gaaagtcaaa aagcgcttac atgattttct gtagaaatgg ggctatcttt
     6901 tgctctggtt ttgtgttata ctagataggt tgcaaagaaa acagtacttt tcttttgtgg
     6961 aaaagaagca acacgatttt atatctagtt atatgaaaat acgtcataaa aagaaaagta
     7021 taaactaagc cctatagggt ggcttcgcac cacctttaga aagaagaata acgtgaaatt
     7081 taatgaatta aacttgtctg ctgatttgct agcagaaatt gaaaaagctg gttttgtaga
     7141 agctagtcct atccaagaac aaactattcc tttggccctt gaaggcaagg atgttatcgg
     7201 tcaagctcag actggtacag gaaaaactgc agcctttggc ttgcctaccc ttgaaaaaat
     7261 ccgtacagaa gaagcgacta tccaagcctt ggtcatcgct ccaactcgtg aactagctgt
     7321 ccaaagtcaa gaagaactct tccgctttgg tcgtagtaag ggagtcaaag tccgttcagt
     7381 atatggcgga tcaagcattg aaaaacaaat taaggctctt aaatctggtg cccatattgt
     7441 ggtgggaact ccaggtcgcc tcttggactt gattaaacgc aaggccttga aattacaaga
     7501 cattgaaacc cttatccttg acgaagcgga tgaaatgctt aacatgggct tccttgaaga
     7561 catcgaagcc attatttccc gtgtacctga gaaccgtcaa actttgcttt tctcagcaac
     7621 tatgccagat gccatcaaac gtatcggtgt tcagtttatg aaagcccctg aacatgtcaa
     7681 gattgcggct aaggaattga caacagaatt ggttgaccag tactatatcc gtgttaagga
     7741 acaagaaaaa tttgacacca tgactcgtct catggatgtg gcacaaccag aactcgctat
     7801 tgtatttggt cgtaccaaac gccgtgtgga tgaattgact cgtggtttga aaattcgtgg
     7861 cttccgtgca gaaggaattc atggcgacct agaccaaaac aaacgtcttc gtgtccttcg
     7921 tgactttaaa aatggcaatc ttgatgtttt ggttgcgaca gacgttgcag cgcgtggttt
     7981 ggatatttca ggtgtgaccc atgtctacaa ctacgatatt ccacaagatc ctgagagtta
     8041 tgttcaccgt atcggtcgta caggtcgtgc tggtaagtca ggtcaatcta ttacttttgt
     8101 tgctccaaac gaaatgggtt accttcaaat cattgaaaac ttgactaaga aacgcatgaa
     8161 aggtctcaaa cctgcaagtg tagaagaatc cttccaatca aaaaaacagg tagctctcaa
     8221 gaaaatcgaa cgtgattttg cagatgaaac cattcgtgcc aactttgaga aatttggtaa
     8281 ggatgctcgc aaattggctg ctgagtttac tccagaagaa ttggcaatgt atatcttgag
     8341 tctgacagtc caagacccag atagccttcc agaagtggag attgcacgtg aaaaaccact
     8401 accgtttaaa ccatcaggta atggtttcgg tggtaaagct aagggaggtc gtggaggccg
     8461 tcgtggggac gaccgtcgag agcgtgatcg ccgtggcaat ggtcgccgtg atgagttcaa
     8521 aaaaggaagt cgtggcaacg atcgttttga taaggaaaaa cgttaccgta aggataataa
     8581 aaaaccacgc aatactttaa gcgaaaagca aacaggcttt gttattcgta acaaaggcga
     8641 taaataagaa aaagcggttc aaaatgaatc gcttttttat ataaggagac cgaatgtgaa
     8701 aagacaaata aaattattat attatctttt ataatgttat aatacacaaa aataggcaac
     8761 ttgtcaatag aaaaggaaca atttaattaa aaatattctg gtttttaatt aaattgtaag
     8821 tcaatgcaag tcaataagga attttcagat aattattgaa aaagagacgt ttttatgtta
     8881 taatgatagc gattaaattc gaggtgaaaa atggcacatt tattagaaaa aactagaaaa
     8941 attacatcaa ttttgaaacg ctcagaggag cagttgcagg atgagcttcc ttacaacgct
     9001 attacgcgtc agttagcgga tattattcat tgcaatgcct gcattatcaa tagtaaggga
     9061 cgtctgcttg gctattttat gcgttataaa acaaatacag atcgcgtaga gcaattcttc
     9121 caaactaaga ttttcccaga tgactacgtt caaggggcta atatgattta cgaaacagaa
     9181 gcaaacttac ctgttgagca tgatatgagt attttccctg ttgagagtag agatgatttt
     9241 ccagatggct tgacgactat tgcaccgatt catgtatcgg ggattcgcct tggttctttg
     9301 attatttggc gtaatgataa aaaattcgaa gatgaggact tggttcttgt tgagattgcc
     9361 agtaccgttg ttgggattca gcttcttaac ttccaacgtg aagaagatga gaaaaatatt
     9421 cgtcgtcgta ctgctgtcac catggcggtc aatacccttt cttactccga actccgtgct
     9481 gtttcagcaa ttttagggga attaaatgga aatgaaggga agttgactgc gtcagtgatt
     9541 gcagatcgta tcggaatcac tcgctctgtg attgtcaatg ctcttcgtaa acttgagtct
     9601 gcggggatta ttgaaagtcg ctcacttgga atgaagggaa cctatcttaa ggtcttgatt
     9661 tcagatattt ttgaagaagt gaagaaaaga gattactaat gacaaaggct ttaatttcga
     9721 ttgattatac agaagatttt gttgctgata gtgggaaact aacagcaggt gctccagctc
     9781 aggcgatttc ggatgccatc agcaaggtaa ctcgattagc ttttgaacga ggagattata
     9841 tcttctttac tattgatgct catgaagaaa acgattgttt ccatccggaa agtaagttat
     9901 ttcctcctca taatctgatt gggacgagtg gacggaattt atatggagat ttggggatct
     9961 tttatcaaga gcatggttca gacagtcgtg tcttttggat ggataaacgc cattactcag
    10021 ctttttcagg gactgaccta gatattcgtt tgagagagcg tagagtgtct accgttatct
    10081 taacaggtgt cttgacggat atctgtgtcc tacatacagc tatagatgcc tataatctag
    10141 gatatgacat cgagattgtt aaaccagctg ttgcttccat ctggcctgaa aatcatcaat
    10201 ttgccctagg tcatttcaaa aatacactcg gagctaagtt agtagatgaa aatctaaatg
    10261 aactttctga gtaacctggt tggtgaaaat gaaaaaattt gaaaaaaagt gttgacaagc
    10321 atcccaaaag ttgatatact agtaaagtaa tcgacgcggg gatggcggaa ttggcagacg
    10381 cgcaggacta aggatcctgt gaccgcttta ggtcgtgagg gttcaagtcc ctctctccgc
    10441 ataggaaaag agctagctaa agctagctct tttgtatttc tctaaaaaat tagaatccag
    10501 tcaaatgtag tggagaatca gcgaaaatat gggaaaactg atccttgttt ctgcttttgt
    10561 catagaagaa taataaagat tatcttcttc aaattctccg atattctcta aagttttgtg
    10621 caagttgcac agaacttgtt tatttttttg gtcatcttgc catagaaata taaagcgttt
    10681 tcatatataa tataattatc aaaagacaaa aggagttcac ctcatggtag aattgaatct
    10741 taaaaatatt tacaaaaaat atccaaacag cgaacactat tcagttgaag atttcaactt
    10801 gaacatcaaa gataaagaat ttatcgtttt cgtaggacct tcaggatgtg gtaaatcaac
    10861 tacactccgt atgattgctg gtcttgaaga cattacagaa ggtactgcat ctatcgatgg
    10921 cgtagttgtc aacgacgtag ctccaaaaga ccgtgatatc gccatggtat tccaaaacta
    10981 cgctctttac ccacacatga ctgtttatga caacatggct ttcggtttga aattgcgtaa
    11041 atacagcaaa gaagacatta acaaacgtgt tcaagaagca gctgaaatac ttggattgaa
    11101 agaattcttg gaacgtaaac cagctgacct ttcaggtggt caacgtcaac gtgttgccat
    11161 ggggcgtgcg attgtccgtg atgcgaaagt attcttgatg gacgaacctt tgtcaaactt
    11221 ggatgccaaa cttcgtgtat caatgcgtgc tgaaatcgct aaaattcacc gtcgtatcgg
    11281 agctacaact atctatgtaa ctcacgacca aacagaagcg atgacacttg cagaccgtat
    11341 cgttattatg tcagctacta agaaccctgc tggtacaggt actatcggac gtgtagaaca
    11401 aatcggtact cctcaagaag tttacaaaaa tccagttaac aaattcgttg caggattcat
    11461 cggaagccca gctatgaact tcatcaccgt gaaattggtt ggtagcgaaa ttgtttctga
    11521 cggtttccgt ttgaaagtgc cagaaggagc attgaaagtt cttcgtgaaa aaggctacga
    11581 aggaaaagaa ttgatctttg gtatccgtcc agaagacgtg aatgcagaac ctgctttcct
    11641 tgaaacattc ccagactgtg ttgtaaaagc gactatctct gtatcagaac tgcttggttc
    11701 agaatctcac ctttactgcc aagttggtaa agacgagttt gttgcaaaag ttgatgctcg
    11761 tgactacttg caaacaggtg caacagttga gcttggattt gacttgaaca aagcacactt
    11821 cttcgatgta gaaactgaaa aaacaatcta ctaaaataaa taaaattcaa agcactacaa
    11881 gaaaagatat ctctttatca attgtagtgg agagatatca gttaatctag ggagagaaac
    11941 aaaatgcttc tctccttttt gctagagaag tcatattatg catctatatt gtgatgctct
    12001 ttaatactct tcgaaaatct cttcaaacca cgtcaacgtc gccttgccgt acgtatgatt
    12061 actgatttcg tcagttttat ctgcaacctc aaagatgtac tttgagcagc ttacggctag
    12121 tttcctagtt tgctctttga tttccattga gtattatttg tgggtaccat ctacaagtga
    12181 agctatatgc gtaaactacg tgagcaattg aattcgaact agagaggtaa taataaattt
    12241 atgctatagt tatggtgact tgtatgcttt tgattctagt ttatcaaata atagattaga
    12301 attgtcagat aatatcattt tgtgttataa tgaagaaaaa acagaggtgt tcaaatgtca
    12361 gaagcaggtc ataagttttt agcaaaattg gggaaaaaac gcttacgtcc aggtggaaag
    12421 cgtgccacag attggttaat tgcagaagga ggattttcaa aagaaaagag aatactagag
    12481 gttgcgtgta ataggggaac tacagcaatt gagttggcac agcgttttgg ttgcaagata
    12541 actgctgttg atatggatgc tcaagcttta gaagtggcta aaaaatctgc tggaacggca
    12601 ggtgttgctc atttaatcag ttttgaaaga gcaaatgcaa tgaaacttcc ttatcaagat
    12661 gctagttttg atattgttat aaatgaagct atgctgacta tgcaagccga tcaagctaag
    12721 aaaaaatgtg taatggaata tctaagggta ttaaaacctg gaggtcttct cttgacacat
    12781 gatgtgcttc ttaaggaagc taaagagtct atcagacagg aattatcaca agcaattcat
    12841 gtaaatgtag gtcctttaac tcaagatggt tgggaacagg tgatgataga atcaggttat
    12901 tgtgatgtga aagcattgac tggtgaaatg acattaatga aattatcggg tatgatttat
    12961 gacgaaggtt tgctaggaac tttgaaaatt tgtgtaaatg cttgtaaaaa ggagaataga
    13021 aagcagtttt taactatgta taaaatgttt gctaagaata aacagaaatt gggctttatt
    13081 gcgatggcta gttataaatc gtcaaaacgt tagataatta ttgaagttaa cttttccttt
    13141 tttctttctt aaaaaatatg ctataataga gagtaaaaaa ctttgaaaga aagaaaaaga
    13201 tgaatttaaa agattacatt gcaacaattg aaaattatcc aaaggaaggc attaccttcc
    13261 gtgatattag tcctttgatg gctgatggaa atgcttatag ctacgctgtt cgtgaaatcg
    13321 ttcagtatgc tactgacaag aaagtcgaca tgatcgtggg acctgaagct cgtggattta
    13381 tcgtgggttg tccagttgcc tttgagttgg gaattggttt tgcgcctgtt cgtaagccag
    13441 gtaaattgcc acgcgaagtt atttctgctg actatgaaaa agagtacggt gtcgatacct
    13501 tgactatgca cgcggatgcc attaagccag gtcaacgtgt tcttattgta gatgaccttt
    13561 tggcgacagg tggaactgtt aaggcaacta tcgagatgat tgaaaaactt ggtggtgtta
    13621 tggcaggttg tgccttcctt gttgaattgg atgaattgaa cggccgtgaa aaaattggtg
    13681 actacgacta caaagttctt atgcattatt aatgaaaaca gtccctaggg ctgttttctc
    13741 tacactagga tataaaaata gactataact agttagagaa aaactataat tgaaaactat
    13801 atcttcttac agtataataa aaggactaag tgtttgagat ttgtcttcaa acatatgcaa
    13861 ttattcctga aagagtacag ttaggagagg gttatgccga ttcgaattga taaaaaattg
    13921 ccagctgttg agattttacg gacagagaat atctttgtca tggatgatca acgtgctgcc
    13981 caccaagata tccgtccttt gaagatttta attttaaatc tcatgccaca gaaaatggtc
    14041 acagagaccc agttgttgcg ccacttggct aatacacccc tacaactgga tattgatttt
    14101 ctctatatgg agagccaccg ttctaaaaca actcgttcag agcacatgga gaccttctat
    14161 aaaacttttc ctgaagtcaa ggatgagtat tttgatggga tgatcatcac gggtgctcca
    14221 gttgagcatt taccatttga ggaagtggac tattgggagg aatttagaca gatgcttgag
    14281 tggtctaaga ctcatgtcta ttcgaccctt catatctgtt ggggggctca ggctgggctt
    14341 tatctgcgct atggtgtaga aaaataccag atggacagta agctatcagg tatttatcct
    14401 caggacaccc taaaagaggg tcaccttcta tttagaggct ttgatgatag ctatgtatcc
    14461 cctcattcac ggcacacgga gatttctaag gaagaggtct taaacaagac caatctcgag
    14521 attttatcag aaggacctca ggttggggtt tctattttgg ccagtcgtga tttacgagaa
    14581 atttatagtt ttggtcattt ggagtatgac cgtgatacct tggcaaaaga gtattttcga
    14641 gatcgtgatg caggtttcga cccacatatt ccagaaaatt actttaaaga tgatgatgtt
    14701 aatcaggtac cttgtctttg ttggtcttca tctgcagccc tctttttcag taattgggta
    14761 aaccatgcgg tctatcagga gacgcctttt gattggagaa agatagaaga tgatgcatct
    14821 gcatatgggt atttataaga ggaattatga catatttaga cgcttttaaa tcaggtacct
    14881 tggttttacc gagtgccctg ctcttgcatt ttaaggaact ctttccttct agcgacgatt
    14941 ttctggtttg gcaatttttc tatttgcaaa atacgacagg cttagaagaa atgtcgccaa
    15001 gccagattgc tgaaaggatt ggcaaggaaa tttcggatgt caaccagtcc atttctaatc
    15061 tgacggaaag gggactgctc cagtatcgta ctatcgaatt aaatggcgaa attgaattgc
    15121 tctttgatgc tagtttggcc ttggaacgtt tggatgacct gtttggagca gttcattcaa
    15181 gttcagacca gctaacacct caaaaccagc tcaaggattt ggtggaaacc ttccagcagg
    15241 agttgggacg attgttgacg ccttttgaga ttgaggattt gaccaagaca ctaaaggaag
    15301 atggaaccag tgctgacttg attaaggagg ctcttcgtga agctgttttg aatggaaaac
    15361 caaactggaa gtacattcag gcgattttga gaaactggcg ccatgaagga atcaagagtg
    15421 tggctcaaat tgaggccaag agagcagaaa gagaagcaag caatcctcag ttgacacagg
    15481 tatctgcaga tttcagaaat gccatggatc tctggaagga ttaatccatg caagtaggct
    15541 tgaaatccga gtaagatttg caagctgtgt ataattgtga tagaataaat agaaaataaa
    15601 ttgaaaaaag aggtatgtga aatgtcacgt aaaccattta tcgctggtaa ctggaaaatg
    15661 aacaaaaatc cagaagaagc taaagcattc gttgaagcag ttgcatcaaa acttccttca
    15721 tcagatcttg ttgaagcagg tatcgctgct ccagctcttg atttgacaac tgttcttgct
    15781 gttgcaaaag gctcaaacct taaagttgct gctcaaaact gctactttga aaatgcaggt
    15841 gctttcactg gtgaaactag cccacaagtt ttgaaagaaa tcggtactga ctacgttgtt
    15901 atcggtcact cagaacgccg tgactacttc catgaaactg acgaagatat caacaaaaaa
    15961 gcaaaagcaa tctttgcgaa cggtatgctt ccaatcatct gttgtggtga atcacttgaa
    16021 acttacgaag ctggtaaagc tgctgaattc gtaggtgctc aagtatctgc tgcattggct
    16081 ggattgactg ctgaacaagt tgctgcctca gttatcgctt atgagccaat ctgggctatc
    16141 ggtactggta aatcagcttc acaagacgat gcacaaaaaa tgtgtaaagt tgttcgtgac
    16201 gttgtagctg ctgactttgg tcaagaagtc gcagacaaag ttcgtgttca atacggtggt
    16261 tctgttaaac ctgaaaatgt tgcttcatac atggcttgcc cagacgttga cggtgccctt
    16321 gtaggtggtg cgtcacttga agctgaaagc ttcttggctt tgcttgactt tgtaaaataa
    16381 tcagtaagta gcaaaagcta ggtggaacag cattcagatg tctgttacat tttttatagg
    16441 agagcaaaga ttgaaaacaa aaattggatt agcaagtatc tgtttactag gcttggcaac
    16501 tagtcatgtc gctgcaaatg aaactgaagt agcaaaaact tcgcaggata caacgacagc
    16561 ttcaagtagt tcagagcaaa atcagtcttc taataaaacg caaacgagcg cagaagtaca
    16621 gactaatgct gctgcccact gggatgggga ttattatgta aaggatgatg gttctaaagc
    16681 tcaaagtgaa tggatttttg acaactacta taaggcttgg ttttatatta attcagatgg
    16741 tcgttactcg cagaatgaat ggcatggaaa ttactacctg aaatcaggtg gatatatggc
    16801 ccaaaacgag tggatctatg acagtaatta caagagttgg ttttatctca agtcagatgg
    16861 ggcttatgct catcaagaat ggcaattgat tggaaataag tggtactact tcaagaagtg
    16921 gggttacatg gctaaaagcc aatggcaagg aagttatttc ttgaatggtc aaggagctat
    16981 gatgcaaaat gaatggctct atgatccagc ctattctgct tatttttatc taaaatccga
    17041 tggaacttat gctaaccaag agtggcaaaa agtgggcggc aaatggtact atttcaagaa
    17101 gtggggctat atggctcgga atgagtggca aggcaactac tatttgactg gaagtggtgc
    17161 tatggcgact gacgaagtga ttatggatgg tgttcgctat atctttgcgg cctctggtga
    17221 gctcaaagaa aagaaagatt tgaatgtcgg ctgggttcac agagatggta aacgctattt
    17281 ctttaataat agagaagaac aagtgggaac cgaacatgct aagaaaatca ttgatattag
    17341 tgagcacaat ggtcgtatca atgattggaa aaaggttatt gatgagaacg aggtggatgg
    17401 tgtcattgtt cgtctaggtt atagcggtaa agaagacaag gaattggcgc ataacattaa
    17461 ggagttaaaa cgtctgggaa ttccttatgg tgtctatctc tatacctatg ctgaaaatga
    17521 gaccgatgct gagaatgacg ctaaacagac cattgaactt ataaagaaat acaatatgaa
    17581 cctgtcttac cctatctatt atgatgttga gaactgggaa tatgtaaata agagcaagag
    17641 agctccaagt gatacagaca cttgggttaa aatcatcaac aagtacatgg acacgatgaa
    17701 gcaggcgggt tatcaaaatg tgtatgtcta tagctatcgt agtttattac agacgcgttt
    17761 aaaacaccca gatattttaa aacatgtaaa ctgggtagcg gcctatacga atgctttaga
    17821 atgggaaaac ccttattatt caggagaaaa aggttggcaa tatacctctt ctgaatacat
    17881 gaaaggaatc caagggcgcg tagatgtcag cgtttggtat taagcgatga tttgaaagag
    17941 ggatgtgata gtagcaccct ctttttcttt gttttatgat agttcatcct cgagtaaatt
    18001 caagatcttg ctcggaaatg aagcttatat agtagattga atatagacaa ataccttgtg
    18061 attggtaaaa cattttagaa attcatttac ctttcctaat cgacttggtt tcatcttatt
    18121 tcaatctatt atagtattgg ggaatttctt caaaccacat cagcttggtc agttctacct
    18181 gcgacctcaa aacttgtgct ttggtcaagc tgggtttagt ttcctagttt gctgatggat
    18241 ttccattgac tataagcatc caaccctctt tttgtcttct aaagaattct taaattatca
    18301 gtctattgca acttttctca tgtgggtcat ttggcttgca attgtctttc cttagtagta
    18361 tactgaggta gtaatcatta agaagtggtt acataaaaat aatgaatgag gtaaaataaa
    18421 atggtagaat tgaaaaaaga agcagcaaaa gatgtcgcaa cattaacaaa agcagcgcca
    18481 gtagcattgg caaaaacaaa ggaagttttg aatcaagcag ttgctgattt gtatgtagct
    18541 cacgttgctt tgcaccaagt gcactggtat atgcatggtc gtggtttcct tgtatggcat
    18601 ccaaaaatgg atgagtacat ggaagctctt gatggtcatt tagatgaaat cagcgaacgc
    18661 ttgatcacac ttggtggaag cccattctct actttgacag agttccttca aaacagtgaa
    18721 atcgaagaag aagctggtga ataccgtaat gttgaagaaa gcttggaacg tgttctagct
    18781 atttatcgct acctcatcac tcttttccaa aaagcgttgg atgtgactga cgaagaaggc
    18841 gatgatgtta caaacgatat ttttgttggt gctaaggctg aacttgagaa aacagtttgg
    18901 atgcttgccg cagaacttgg acaagcacct ggtttgtaag aaacaagaca acatagataa
    18961 atctgtagga aatttcttac agattttttc tattttgtaa gctattccaa accagtcttt
    19021 ttttgagttt tttgataaaa tagtactatc agtgaaaagg atggaagcat gactaagaaa
    19081 atcgtagcta tttgggccca ggatgaagag ggtgtgattg gtaaggacaa tcgtctgcct
    19141 tggcatttgc cagcagaatt gcagcacttt aaagaaacaa ctctgaatca tgctatcttg
    19201 atggggcggg taacctttga tggaatgggg cgtcgcttgc ttccaaaacg ggagaccctg
    19261 attttgacgc gtaatccgga agaaaagata gatggggttg ctacttttca ggacgtccag
    19321 tctgttcttg actggtatca ggctcaagaa aagaatctct acattatcgg tgggaagcaa
    19381 atttttcagg cttttgaagc ttaccttgat gaagtgattg tcactcacat tcatgctcgg
    19441 gtggaaggag atacctattt ccctgaagag cttgacttgt ctctttttga gacagtttca
    19501 agcaaatttt acgccaaaga tgagaagaat ccttatgatt ttaccatcca ataccgcaag
    19561 agaaaggaag tataatggaa cggagtttat ttggtctatt cacggctttt ctgtgtttca
    19621 tctgctttct ggcaggagca caggcttttc gtaaaaagcg ttacgggctt tctatcctcc
    19681 tttggttaaa tgcctttacc aatctggtca atagtattca tgctttttac atgaccttat
    19741 tttagataga atgacagtat agaatggaag gaaatcatgt ctacaaatag aaaaaatgat
    19801 atgatggttt attgctcatt ttgtggcaaa aaccaagaag aagtacaaaa aataattgct
    19861 ggcaacaatg cttttatttg taatgaatgc gtggagttag ctcaggaaat cattcgagaa
    19921 gaattggttg aggaagtctt ggcagacttg tctgaggtgc caaaaccaat tgaactcctc
    19981 catatcttga accactatgt aattggtcaa gatcgtgcca agcgtgcctt ggcagtggcg
    20041 gtttataacc actacaaacg catcaatttc cacgatacac gcgaagagtc agaagatgtg
    20101 gatttgcaga agtcaaacat tttgatgatt ggcccaactg gttcagggaa aactttcctt
    20161 gcccagacct tggctaagag cttgaatgtg ccttttgcta ttgcggatgc gacagctctg
    20221 acggaggctg gttatgtggg tgaggacgtg gaaaatatcc tcctcaaact cttgcaggtt
    20281 gctgacttta acatcgaacg tgcagagcgt ggcattatct atgtggatga aattgacaag
    20341 attgccaaga agagtgagaa tgtgtctatc acacgtgatg tttctggtga aggggtgcaa
    20401 caagcccttc tcaagattat cgagggaact gttgctagcg tgccgcctca aggtggacgc
    20461 aaacatccac aacaagagat gattcaagtg gatacaaaaa atatcctctt catcgtgggt
    20521 ggtgcttttg atggtattga agaaattgtc aaacaacgta tgggtgaaaa agtcatcgga
    20581 tttggtcaaa acaataaggc gattgacgaa aacagctcat acatgcaaga aatcatcgct
    20641 gaagacattc aaaaatttgg tattatccct gagttgattg gacgcttgcc tgtttttgcg
    20701 gctcttgagc aattgaccgt tgatgacttg gttcgcatct tgaaagagcc aagaaatgcc
    20761 ttggtgaaac aataccaaac cttgctttct tatgatgatg ttgagttgga atttgacgac
    20821 gaagcccttc aagagattgc taataaagca atcgaacgga agacaggggc gcgtggactt
    20881 cgctccatca tcgaagaaac catgctagat gtcatgtttg aggtgccgag tcaggaaaat
    20941 gtgaaattgg ttcgcatcac taaagaaact gtcgatggaa cggataaacc gattctagaa
    21001 acagcctaga ggtgactatg gaacttaata cacacaatgc tgaaatcttg ctcagtgcag
    21061 ctaataagtc ccactatccg caggatgaac tgccagagat tgccctagca gggcgttcaa
    21121 atgttggtaa atccagcttt atcaacacta tgttgaaccg taagaatctc gcccgtacat
    21181 caggaaaacc tggtaaaacc cagctcctga acttttttaa cattgatgac aagatgcgct
    21241 ttgtggatgt gcctggttat ggctatgctc gtgtttctaa aaaggaacgt gaaaagtggg
    21301 ggtgcatgat tgaggagtac ttaacgactc gggaaaatct ccgtgcggtt gtcagtctag
    21361 ttgaccttcg tcatgacccg tcagcagatg atgtgcagat gtacgaattt ctcaagtatt
    21421 atgagattcc agtcatcatt gtggcgacca aggcggacaa gattcctcgt ggtaaatgga
    21481 acaagcatga atcagcaatc aaaaagaaat taaactttga cccaagtgac gatttcatcc
    21541 tcttttcatc tgtcagcaag gcagggatgg atgaggcttg ggatgcaatc ttagaaaaat
    21601 tgtgaggaaa agaaaatggc aaaaacaatt catacagata aggccccaaa ggctatcgga
    21661 ccctatgttc aaggaaaaat cgttggcaac cttttgtttg ctagcggtca agttccccta
    21721 tcccctgaaa ctggggaaat tgtaggagag aatatccaag aacagacaga gcaagtcttg
    21781 aaaaacatcg gtgctatttt ggcagaagca ggaacagact ttgaccatgt tgtcaaaaca
    21841 acttgcttct tgagcgatat gaacgacttt gttcctttta atgaggttta ccaaacggcc
    21901 ttcaaagagg aattcccagc tcgttcagct gtggaggtag ctcgtcttcc tcgtgatgta
    21961 aaagtcgaaa ttgaagtcat cgcagagatt ggataagcta gttgaagttt ggtgttgcca
    22021 aacttctttt gatataagga gaaaaagatg acaaagaaac aacttcactt ggtgattgtg
    22081 acagggatga gtggcgcagg gaaaactgta gccattcagt ccttcgagga tctaggttat
    22141 ttcaccattg ataatatgcc gccagctctc ttgcctaagt ttttgcagct ggttgaaatt
    22201 aaggaagaca atcctaagtt ggccttggta gtggatatgc gtagccgttc tttcttttca
    22261 gagattcaag ctgttttgga tgagttggaa aatcaagatg gtttggattt caaaatcctc
    22321 tttttggatg cggctgataa ggaattggtc gctcgttaca aggaaaccag acggagtcac
    22381 ccactagcag cagacggtcg tattttagat ggaatcaagt tggaacgtga actcttggca
    22441 cctttgaaaa atatgagcca aaatgtggtg gatacgactg aactcactcc acgtgagctg
    22501 cgcaaaaccc ttgcagagca gttttcagac caagaacaag cccagtcttt ccgtatcgaa
    22561 gtcatgtctt tcggatttaa gtatggaatc ccgattgatg cggacttggt ctttgatgtc
    22621 cgtttcttgc caaatcccta ttatttacca gaactgagaa accaaacggg tgtggatgaa
    22681 cctgtttatg attatgtcat gaaccatcct gagtcagaag acttttatca acatttattg
    22741 gccttgattg agccgattct gccaagttac caaaaggaag gtaagtccgt tttgaccatt
    22801 gccatgggat gtacgggtgg acaacaccgt agtgtggcat ttgctaaacg cttggtgcag
    22861 gacttatcca agaattggtc tgttaatgaa gggcatcgcg acaaagaccg cagaaaggaa
    22921 acggtaaacc gttcatgaga aaaccaaaga taacggtgat tggtggaggg actggaattc
    22981 ccgtcattct aaaaagtctg cgggaaaaag atgtggaaat cgcagctatc gtgacggtgg
    23041 cagatgatgg tggttcttca ggtgaactcc gaaaaaatat gcaacagttg acaccgccag
    23101 gtgatcttcg taatgtcctt gtggccatgt cggatatgcc taagttttat gagaaggtct
    23161 ttcagtatcg gttctctgag gatgccggag cctttgctgg ccatccattg ggaaatctca
    23221 tcattgctgg cttgtcagaa atgcagggtt caacctataa tgccatgcag ttattgagca
    23281 aatttttcca tacaacaggg aaaatttatc cttccagtga ccatcctttg acccttcatg
    23341 cagtctttca ggatgggaca gaagtggctg gagagagtca tattgtagac catcgaggca
    23401 taattgacaa tgtctatgtg accaatgccc taaacgatga tacgcctctg gccagccgtc
    23461 gagtagtgca gaccatcctt gaaagtgaca tgattgtcct agggccaggt tctctcttta
    23521 cctctatttt gcccaatatc gtgattaagg aaattgggcg ggctcttttg gaaaccaagg
    23581 cagaaattgc ctatgtctgc aatatcatga cccaacgtgg ggagacggaa cactttacag
    23641 atagcgacca cgtggaagtc ttgcatcgtc accttggtcg cccttttatc gacactgtct
    23701 tggtgaatat tgaaaaagtg cctcaggaat acatgaattc caaccgtttt gatgaatact
    23761 tggtgcaagt ggaacacgat tttgtaggtc tttgtaagca agtttcgcgc gtgatttcat
    23821 ctaacttcct tcgtctggaa aatggcggtg ccttccacga tggagatttg attgtggacg
    23881 agttgatgcg cattatacag gtgaaaaaat gagtttcaca gtagcagtaa aagaagaaat
    23941 cctgggccaa caccatctga gctggcatga attatctgcc attatcaaaa tgtctggtag
    24001 catcggtctc tcgacttcgg gcttgacttt gtcagttgtg acagaaaatg ccaaactggc
    24061 ccgtcacctc tatgagtcct ttctccattt ctatgaaatc aaatctgaaa ttcgtcacca
    24121 ccaacggagc aatcttcgca agaatcgcgt ctataccgtt tttacagatg aaaaggtgca
    24181 ggatttgtta agtgatttgc acttggcaga ctctttcttt ggcctggaaa caggtattga
    24241 tgaggcgatt ttatcggatg aggaagcagg tcgtgcctat ctctgtggcg ctttcttggc
    24301 aaatgggagc attcgtgacc ctgagtcagg caagtaccag ttggaaatca gttctgttta
    24361 tctggaccac gcgcaaggaa ttgcctccct tctccaacag tttttactgg atgccaaggt
    24421 gcttgagcgc aagaaggggg ctgtgaccta tctccagcga gcagaagaca ttatggactt
    24481 cttgatagta atcggagcca tgcaggcacg tgatgatttt gagcgggtta agattttgcg
    24541 agaaacccgt aacgacctca atcgggctaa taatgccgag acagctaata tcgctcggac
    24601 agtttctgcc agcatgaaga ccattaacaa tatcagtaaa ataaaagata tcatgggctt
    24661 agaaaatttg ccagtagatt tgcaggaagt ggcgcaactg aggattcagc acccagacta
    24721 ctctatccaa cagttggcag atagcctcag cacccctctg accaaaagtg gtgtcaatca
    24781 cagactcaga aaaatcaata agatagcgga tgaattataa cgatataaag caaccccttg
    24841 aattatcaat atcttcaagg ggttttgttg tgttatgaaa tcaaaaaggg gcaaccaagg
    24901 ggcagaatta aaaaatagta tctaatttat tgaccagttt atcctccata tcttcagtag
    24961 tatgagaata gatttccaaa gtcatttttg catttgagtg cccaactcga tccattattg
    25021 attttattgg gaggccagac tctgctaaaa acgaaatatg agaatgccta aaaatatggc
    25081 tagataaatt tttttctatt ttggcctgtt ttccatattt ttttaatatc tgtatgaagc
    25141 aagctattgt tgtaggttga ttccattttt caaaacagaa aatataatca tcgcttgaca
    25201 atggctggaa acgttcgcta agtcgtacta tttgtctttg aatagcttct atgacactct
    25261 ctgatacttt gattgtccgt attgaatttg tagtctttgg tagcgtcttg attttgttta
    25321 ctgaatcaaa attacctgtg atctcaattt tgttgttttc gaagtctata ttcttcagtt
    25381 gtaaggcagt taactcacca tatctcatac cagttaatgt cagcacaaga accatatcag
    25441 cgtacttttg gtgatattct cgacgattaa ggacatcgac aagtgctttt atttcttgca
    25501 tggtgagaaa gttgttacgc tttttttcca gttcttctaa agtctttggt ttttgaggaa
    25561 tcgtagtata atcgacctcg ttgttttcaa tgtaagagta ttgaacagcg taattaaaga
    25621 tacctctgag cctatgccgt acttttttag ctgtaatata tccgttgctt tcaataattt
    25681 tttcaatagc ctcttgaaga aaacgcctgt caagattagc aagtatggta tcggatggta
    25741 tgacttcttt catcttctta tcaactgatt tacaattatg ttttgttgat tcctttactg
    25801 tttgcgccca tgatttatag aaaaggttat agatttcttc aaatgtaatg ctttctactt
    25861 gttttgtgct gagtttttta tttatcttct cttgtaacaa gatagcagct tgatttcttg
    25921 cctggggagt tttcttctcc atggttactg aaactttttt taatttctca gtatatggat
    25981 ctttatatcg ctcaaaaaat ttatatttgc cgtttggcaa ttcttccatc cacattgcgt
    26041 ttacctcact tttttgttaa aatgggtata gtaaaaaggg ctttttaatg ccttttacta
    26101 tactggatat cctcacactc aaagtttggc gatggcgagt gtgaggattt tttgttttta
    26161 tagttattct gatgaactat cctatcaatt cataatattc gtcaattacc atcaattcgt
    26221 ctgtgactgt tctaagctta tgtttttgca tgaactggat atagttgaaa gattgatggt
    26281 cgtctgatag tgcaagttct tcttctagca acttatgaat catgtgccta ttagcctcat
    26341 tctcgcacct agtgtggttg ttttgatata gtgcagtaga atgttccaga tgtcctaatt
    26401 cgtggtatat gacccgtttt tttgcatctt cggacagttc acggtttata aagataatac
    26461 tgatttcttt gatataaact ccaggttttt gccaaagttc gttatcaaag taagcgagag
    26521 tgacaccgtg tgagtcaact agctcttcaa tagtcatagg ctatcatcct tcaaatattt
    26581 tttaaaatta gttgttttat ctcttgaact agagtaaaat agaattgaaa ggaagtgatt
    26641 aaaatgaagt tgaaactcta tgcacattta gctgtactgt ttcaagtttc agcatttgtt
    26701 tttttgattt gttacttttt tctaagacaa atcctaacac ttccaatcat cgttttactc
    26761 agtttcgtta tttctgaaat tattcttcga ctttttctgg agattcgagt agttcatctt
    26821 gaagaatcct agttgctact tctggagctt taatatctag ttgagatgta gcgcctttaa
    26881 actgcggact catcccttta tctattaaca atgcaatagc ctcggcattt attttatttg
    26941 cctgggcttt tttgattgct tcatccccat cgctatttaa ctgagcttta aatttcccaa
    27001 gcttagaatc aacttcaaag tttgcaccat tgcgtttaat taaattgcga aaagcaattc
    27061 ctccagttag aataatgata aatactagaa ccgggattag tatttcagga tgtccaagta
    27121 gttcaatcgg ccctttcgat tggacgttgg ttcttagaac gactttctca tcttttaatt
    27181 catcagattc ttttacaaca ttgaccattt gcaagacagt gtgcagaaat gttgagtatt
    27241 caaaagcatc aatattgttt tcctcttgta ctttgaaagt gatactcatg tggtcatgat
    27301 cgatgtaggc atcatataga cctcggttga tgaatttttt gtaggcattt gcatcagtga
    27361 tggtatggcc tgaatagact aatttgtaaa gtttcgggtc aatatctctg tttggtatga
    27421 ctccaaacca gtgcacattc attcgcttat taaatgggca aacgttagat gcggactcta
    27481 tgttgctttc actctctgta tagggtctgc tcgttatttc acctacaaga aaatcgttag
    27541 gagattctga cggaacaatg acaatgtctc cgattttaag actatacgca aacttcatca
    27601 tttgattgta ggcagaacca ggcttttcta tcctactgtc aaactccttg atttttcctt
    27661 tgattgcatc ttcgtcaaga tttttaaggt catctaatgt tatatagttc catccaatgg
    27721 cgatatagcc accagtttga aaacttttat agaattgccc tttttgagcc cttacaaacc
    27781 aataatcttt agaactatca acagacggga gttgatgata tatgttttca aaaagggtat
    27841 tgaaaagcaa ggcatcttgt tcggtaatcg tcatactatc tacctctcaa gtatatttct
    27901 atgatgtttt gaatcgcatc gatatcctct tctgtaagtg gcttaccatc gaaggttttg
    27961 gcattctctg ccatctttcg gaggtcgtca gacgtgtatc ctgagattgt atcatcacca
    28021 gcaatagcag gattatcagt acgaccaagt aagtagtctg tagatacgtt gaagtagtca
    28081 gcgatctgtt gcaatctttc agagtttggg gttttcgttt ttaaagtata gaaataattg
    28141 gtactatatc ctagactttc ttctagtttt gttagaggaa tccctctttt tttagctaat
    28201 tctttaattt tttctagcgt tgaaaacatt gttaaatcaa cctttctaag ggtatcacaa
    28261 aaaatatttc taaaattcta gaaaaaagta ttgatacaat ctagaaaaaa gtatagaata
    28321 gtttttgtaa gtaagttaca actaaaaaaa caactaagaa ataaattata aaaatgtttt
    28381 ggcgaacggt atttatagtt ttattagtgt ttttgttatg attttatttt agactttatt
    28441 atagactttg tcaataaaaa agtacaaaaa atagttacat ttttagttgt ttcttgttta
    28501 cttgttcctt gacaattgaa tagagcatgt gagataataa aggggaatta aggattagtt
    28561 ctatatcatg gactagaaaa gaccccaggc taacttccac attaagcttg gggtcttttt
    28621 ttgacactat ttgtccttgt tcagccattt atcagctaaa cgaagaacga caccgaccac
    28681 aatcggtccg atgatagttt taaggattag ttccatcatg ggctatctca cctcctttcg
    28741 taggcggtgt agaagtgccg taaaatatta taccacattt ctaattcagc ttgtcaaagg
    28801 tttcttttga caacttaaaa tagatgtgag ataatatagg ggaagtgaag atgtagtcta
    28861 ctacaactac aaaaaagccc ctgctgataa ccacaaaagc aagggctttt tctagtctac
    28921 gctagaaagg tgggttagtc gctatttctt gtttagccat ttttcgatga ctatcaggac
    28981 gataccgacc accaagggta gaataatatt tgtgaagatg taatctacca taggctccac
    29041 ctcccttcta aggcagatgt gccgtcacta ttataccaca tgctctatca gttagatagg
    29101 gcatttttta tttttgaaaa aaggaggaac gtgtcgatgg taagtattct taaaaattta
    29161 gaacaagaaa aagaccacct tgaaaaaatc attaaggtag tcagcgctgg tggtaaattt
    29221 ctgagattgc catatcaaaa aaagtcacgc tcgattagtg agaatctgaa attgatttct
    29281 caaaatcttg ataaattgag cgagcaagtt caacaaacca cgaatcagca ttcatgattt
    29341 caagatgacg aaagaaacct gttttggttt ccagttcaga atcgtgtgca taacgtaata
    29401 tttctctagc aaagatggtt tcaaaatcaa aatctttacc atcatcgtag atgtcgcgtt
    29461 tgcttgcttt gagtaaatat tctttaaaag tcataaggtt aactcctttc tgcttatatt
    29521 atagcagaaa aagaagaaag aaaaagaaag gagaaaatat gccagatatt gcaaacggtc
    29581 gcgaaagagt tattgctttc ttgaaagaga aaggcattaa aaaagcaact ctagcggttg
    29641 cttacggctt taaacgacag gaagtgacaa acattctaag tggaacgact aaaggtccac
    29701 gagcgaacag tttcattctt caggttattg aagattatgg gattgagtag gaaagatttg
    29761 aggagtagga aaatgagacc aagacgatat ccgtatagtg ggaaaaaaga gtccaccttt
    29821 gtaaaggccg accctgagtt agttgaaaaa cttttaagaa acactagttt tcttgagtgt
    29881 ttacaaaaaa agcctatcaa ttttcagata gacttagaag aatttaagcg tcttagctat
    29941 gaagccattc atgatacttc tcaagtaact caacagtagt tattacagaa gtcaaaccac
    30001 tgaccttccc cagttgcaat ccgtctgtat ggtcaatctg tttagtagct tcattagctt
    30061 tagcagagat agcttgcata tcttcagctg ttaaagattc tcgaaaatct ttaaaggatt
    30121 tcataaaaac tcctcctttc tattggaatt ttgactaaaa cggtgagagg tcctagtcga
    30181 gattattata gcaatttagg aggatattac atcggtcttg aggctgattt ttggaggcaa
    30241 tattggaaga taaaatcata gaacttgctg attacttcat cagcgaatct acaacgtaca
    30301 gagaagcaaa aatagcgtgt gagaagctat tgaaacaagt cagccatgag atagaactca
    30361 gggcgatgga aagtaggaca gtctagaaga caacaaaaag cacctgacgg aaatcaggcg
    30421 catacttaaa tattcaacat gattataaca cgaaaggagc aaaaatggaa gtagttgaaa
    30481 ttgtaagaat taaagatgtg attattgaaa aagtctctgc taatgatgaa gagttaaaac
    30541 gtatctttgg atgttcaaaa cgacaagcag gagagcgaag aagagaaatg caaaaactcc
    30601 ctagtcagca aaaacatctt ttggatagtg gacaacttgt aacgattaaa ggtttctatg
    30661 aatacttgca atatcgtgga actaaagctt ggaaaaaaga aatggaaaca agcaagaaaa
    30721 tgaggtcagc aggatgaacc tactatcaag aatcaaaaac tatttttcgg aagaggtcaa
    30781 agaaactaat ctcgactgga aagaggtcgc tttagacctc aatcaatcac taattgaaac
    30841 acaggaaaaa cttcaagaag cgaatcaaga aatcgcagac ttgaagaaaa tcgtagcaat
    30901 ctacaaagaa aaggagaaag aaaaatgatg gaatacattt acctggtaat aatcgtagga
    30961 attggactat ggtcgctagt aaataaacta gatgaccacg ctgaaatgaa acaaaaagag
    31021 cgccagctga tggcaaacaa tgtcgcacgg atgaatctga gaaattcaga taagcaattt
    31081 acttatgatg tagaaccgcc tgaagggttg aaataaggag gagaaacatg actcaagcgg
    31141 aacaaattag ggaatattat agagagcacc ctgctgcctc atgtgatgaa gtggctgagg
    31201 ttgtcggtac aacaaaaagc aacgtaagtg caaacctggc caaagacatc aaggcaggca
    31261 gatgcgttcg cttggaagac aagtcatacg actactcccc ttactttaat cacacacaag
    31321 cgctcactga gttggttgat tggaagaatg ataccagacg tgagtgggtg gatatgctga
    31381 caagagcagc agagaaagaa acggatagca acgttatgcg tttgttaatc aaagaagcaa
    31441 ataaattgat gaaagaggtg actaagtaga tggtacgaaa taaaataggt gatttaacta
    31501 acacgctctt cgctcaatta gagactctgg atgataggga tcttacagca gatgaattaa
    31561 aagtagaatt acagcgctcg aaacaaatgg tcgcaatctc aggtcaaatc ttacaagcag
    31621 gtcaattggc gctagatgct gaaaaattca aagacaaggt aggtgaagtc aatgccccga
    31681 tcgctttgct ggaaggatga gtacacggag tacatgcatg aaatatgccc tggtcgttta
    31741 actcctgaag taaccaggtt gctgaatgaa aaatttggta cgaattataa caagagtcaa
    31801 atcggtggcg tacgcaaacg tctagggtta gcagttggaa aagtctatca aggtcgattg
    31861 ctgacaaagg agcaacatga ttatcttgta ttgatccaaa aaaataagat ttctcgtaat
    31921 gtcgcaaatg aaatgaacca aaaatttggc gtatcgctaa ctgagaaaca gattaagagt
    31981 tatcggagaa ataataatct acatagtggg ttgacgggaa gattcgagaa agatcagact
    32041 cctcacaata aggggaagaa gtaccccaat atgccaaaaa acagcgggca gttcaaaaaa
    32101 ggtaatcgac ctccgaatta tgtacctgtc ggcactatca actacacaac agacggttat
    32161 ccaaaagaaa agattggaga acctaatcaa tgggttttga aacatcgtaa agtctgggag
    32221 gaccatcacg ggctgatacc aaaagggtac tcaatcgttt ttctggacgg tgataaaaca
    32281 aactatgata tttcaaatct ggcatgttta tctaagaacg aaattgctag aatgaatcaa
    32341 aatcatttat tcacgtccaa cgctgatttg actaaatcag gtattggact aacaaaactt
    32401 acaaataaaa tcagagaggt agaaaaaaat ggctagttta tacgaactaa caggtcagtt
    32461 cctgacaatt taccaattgg atatcgatga cgaaacaaaa gcagacacgc ttgaggccat
    32521 cgattggcaa gaacaatttg aacagaaagc agaaggatat gcccatgtta tcaagaatct
    32581 agaagccgac gtggccatgt acaaagctga ggaagagagc ttcaaagcca agaaacaagc
    32641 ggcacagaaa aagctggatt atgtcaagga taacattatg gcagctatga atgtcacagg
    32701 tcaaaccgaa gtcaagagtg gtgccctgat tataaaaatt gctaaaaatc cagaatcagt
    32761 caaggtcaac gaaaatgacc ttccgaaaaa atattttaca aaaaaagtga cgcttgcgcc
    32821 ggacaaaaaa acactcaaag agttgcttaa atctggcaag aaagtcaaag gagccgagct
    32881 cattagaacg gaaaagttgg tgattaagta atggaattga tgaataaaac acgagtaaca
    32941 gattcactag cagttgtgat tggactagaa tcgattgaag tacttgttac tgaaggtttt
    33001 ctatttgatg ttgcgattcg ttttgtaaaa gtagacgaaa caaatcttga tcaaggaaat
    33061 gaaaagccag tattcactcc ggaatacaag ctggtcacag ttgctaaata caaggaaaaa
    33121 cctatctttg aatcggagga agatattcga aaatttgaga agcaagcaaa agaagttaaa
    33181 tcgctatttg cctttgcaaa ggtaaataaa caaaattggt ttaacactgc cctttatcca
    33241 ggagtgctga ctgagaaagt tggtgtttga tgaaaatttt agctattgat ccaagcagta
    33301 ataaaattga aaccagcaca acaggagttg tcttgttgga taatgcaaga ttagttgata
    33361 gctgggttgt ctcttatggt atgagaggtt tcgctgattg gtttcacgaa atcggaacaa
    33421 atcttgaatt cgatgtagtt attgttgaag aatttaaggc gagggataac gaaaagtcaa
    33481 aagataatag cgtggcagaa accatcgctt atatccagct ttgttatcca gaggctattc
    33541 ttcaatttaa tgcaggttac aagtcggata ttccaaacga tcttttgaaa atcttagacc
    33601 tttggaaatt tgaaaaaagt catcatcaag atattagagc agcagcaaga cttggattat
    33661 tttgggcaat gagaaatgat attgaagaag tggttcatga tatcggaaag gtggtgagtg
    33721 agtatcacaa taacgctaag aaagtggcaa gctgaagcga ttaaaagaag tgaacattta
    33781 tctaatggaa tctttttaga ggctcttggg ggcagaggca aaactatctg tgcacttgct
    33841 attgcaaaac ataaaaaagc taaaaaaatc atcatcacaa acaatcgact agctattctg
    33901 aatggttgga tagatgcagt caagtttatg aattttgata aaggtgttga gattatcatt
    33961 cagacagata gatatcttca aaatcaagtc aaaaaggggc ataaattaga ttgtgatgtg
    34021 ctgatagtag acgaatggca gaatatgtct tctgacaaac aagtggcctt atatcgcaaa
    34081 ataaagcgaa aatacacgat aggtctttca gcgacaccaa ttcggaaaaa aggacaaaat
    34141 ttctatccgc ttgaaaaaac ggtatttggt tgggcaaccc caaataataa atttgactgg
    34201 caaaagactc atggaaaaat ggtctatgat ccatttagct attcaaaaga gaagtgggaa
    34261 gattttcaaa attatgaaag ttatatctcg agcttgccta atttcttccg ctgggaagag
    34321 attgaaggaa ttgagaatgc agttgagaat aacggttttg agattaagtt ttaccaaaag
    34381 agagtcgcct ctggcaatcc agaaaaactt gcagaattta gaaaactaaa tcttgtaaca
    34441 gtggacggca aaactgcaat ggccaagcaa tcgtttggaa gaaagacctt tgaacgctac
    34501 cttaatcaaa caggcgtagc agtcgatttt ccaaaattaa agccagtaaa tgcggatacg
    34561 ccattgatgt tacaacttga cggtttaatc gaacgagcac cacacgatat gttgattgtc
    34621 agtaaatcta agcagattgt caacgtcatt agcgagcgcc atcctgaaat tggaatctgg
    34681 acgggcgata ttcaagaagg actttataag aaattcgtgg ttgctactag tcaagtgtta
    34741 ggtgtcggag tagacggctt gcaacacaaa taccaaacta ttgtcgtatt ggatccagta
    34801 gaagaaggtt ctggagaata tgatgattat cgacaattgc tctggcgcat aacaggaagt
    34861 cgtcagcagc atgatgtaaa tgtaattgaa ttttattata aagaaagtta aaaaaaagag
    34921 gaaaacaaaa tgaataaaac aactgaaatg atcgtatttc gtagccgtaa aactggagaa
    34981 tttcttaatt cttacaagga cagaagttct ttagcatttg cagctgactt ttgcagcttg
    35041 gaatattgtt tgaagcttcc tcgtaaaaaa tacgaagaca acaaaaagac ttacaaggct
    35101 cttgctgcag cttttgactg tgaaattgtc gcagttgaag cggaatacaa attgacctat
    35161 ccgaatggat cagaagttga acctatcaag cgtgaccgtt catcaattga ggacatgatt
    35221 aaggatatta ttggaggggt tctctaatgg catttacact tccagcaaat aaaccacaag
    35281 ttcctaaaga taccccacga aattttttca tctacggtga aaccatgagc ggaaagtctt
    35341 atcttgcaaa tgaattccca aatccaatcg ttttgaacac agacgggaat gcagaagcta
    35401 acactgttcc aagcattcag ctgatcaatg aaaaagatga caagggacga attaccaatt
    35461 cagtaattaa gcagcttgga gatatcttgc ttgctctcca gacacagaag cactcttatg
    35521 aaacagtcgt tattgatgta attgacgatg ttattgaaat gattaagatt gcagtttgtg
    35581 atgaattaac cccagttggt aaacctcgct tgaaatcctt gtcggaaatt ccatacggca
    35641 aaggatacga cttctttaac caagctatca cagaattagt cattgacctc aaagcattgc
    35701 caatgaatgt tatttacatc agccgtcagg tatctgaata tgatgacaat ggcaatgcca
    35761 ccaaagacaa accaagcttg aaagataagt atgtcaatct tatcaatgga aactctgatt
    35821 tgatgatcca cactgaaaaa ctcggcaaca actacaaccg tgaggttgac cgcaagcgta
    35881 agacctacta tgtgaaccat gttgatgaca aggctatttt gaaaatctta gcaactatcc
    35941 gtggggctgt tgaacctgca aaaaccgaaa agacaaaaga ggcgcctaag aaagaagttg
    36001 cctctgatga tgaactattt taagaaataa aggagaatac acatgagctt actagatatc
    36061 gcaaaatcaa tcaaaaaaga gggctttgac ccacgcaaag acagcgccaa cggtcctgca
    36121 ccaatcccag ctggtactta tccagtagtc ctgaagaaag caactttcaa cgtatcggac
    36181 aaaggctggg aaagccttgg ttatcaattt gaaatccgtg gcggtgatta cagtggacgc
    36241 tctgaatttg caacatttgg cacactgact gaatggaacg gtaaggacct taactgggca
    36301 gttgaacgca ccatgaaatt ctttatcaaa gccttggtcc ttgctggcga cagtatgcaa
    36361 ggaaatgaag aagacggtaa agccttggaa gaggctctaa aacgtaaggc agttggctct
    36421 tactacaacc ttgttatctc tgtgactaag gggaaagatg gccgtgagtt ccgaaactat
    36481 gaccttgaag aagaagcaca accgctgact gaagctgata ttgatgacga tgacctccct
    36541 ttttaagaaa taacaagttc tgggtcattg atgaaactga tgaaagatta ggaccattca
    36601 atacatttga agaggcttat caatcgttgt tattttattt aaaaatgact gaagatgaat
    36661 atcaatcaaa ttatatggcc caagaacttg tttatattta caaaaaggag aagtaatcat
    36721 gtcgtcgatg aaagaatacg cattacagta ccaaaagtta gggttctcag tcattccaat
    36781 caatcctaaa aacaagatgc ctttgattga ttttgctgat aagccagcca tgactccatc
    36841 tgagattgaa aacttttggg acggctaccc taatgcaaac attgccctaa agattaccaa
    36901 cttctttgtc attgatattg acaaacacgg caaatcgaac ggttttgaat cgctaaaaaa
    36961 atggaaacat ctaaatttaa tcgaaccgac actgcaagct aagacggcta gtggcggtaa
    37021 acatctattc tacttcaaac gagaagatga gccgatcact cagatgattg gattcttgcc
    37081 tggtgttgat attaaggctc acgaaaataa ttatgtgtta gtcgcaccct ctgccacaga
    37141 taaagggcag tatgagtggg atctggaaaa gtctaaggaa ggtggcacga tggtcactcc
    37201 ttcaaaagat ttaatccagt ctataaaaaa acagtatggc gaaactcacg gttataagta
    37261 tgatggtaag gacggtctta gggatttagt tagacgttca catactagag accgaacaca
    37321 gactacagat ctctttgaaa ccatcgccct tggttttggt gatgaaggtg gacgaaatga
    37381 caaactagca aaattcgtag gtggtctctt atatcgtgcg gtcgacgatg gtgtagttgt
    37441 tcaacttgca agattagcaa atgcaaatag tccaaaccct ttgcctgaaa aggaaatgat
    37501 gcgtactatt gaaagtatga ttaaaaaaga taggaggtga ttgtgattgg taatgtagta
    37561 agtattgact cacaacctaa gatgataacg actgccaagg gagacatcaa ggccaacagt
    37621 ccaagtaatg tgttgatgtc tttcaaagct gatgatcagt tgagtattta cctaaagcac
    37681 aacgattttt cccaagagca tgaactcctt aaagatatca agatcggcaa cactcttttt
    37741 aaaaaaggtg agctcccttc taactttgat tcagtcgtaa aagtttactt tgaaagtgtg
    37801 ttaggtgttg ctttctcaaa ccaagcgatg cttgatggca tggagacttt cttttcagaa
    37861 agatcataca atccagttat tgagtatatg gagagagcaa ctgaaaagtg ggacggcaga
    37921 aaccggattg accgcatgct tcaagtatat ctcggcgctg aagatatccc tttagtttct
    37981 aaaatcgctc aaatgtggct agttggtgca gttgctaaag tttatgatcc atacgttaag
    38041 tttgactatg ttctggacct ggtcggtgga caaggagttg ggaaaacgtc cctccttcaa
    38101 aaattgggtg gcgaatggta tacggatgcc gtaacagatt tctctaataa agataattac
    38161 gacattatgt taaagagtct aatcgtcaac gatgatgaaa tggtggccag taatcggatg
    38221 agctttgcag aaactaaggc ctttatttct aaaactagcc tacgttatcg taaaccatac
    38281 atgaaacgaa cagaagaatt tgccaagaac ttcatcttag ccaggactac taatcaaaaa
    38341 gaatacctca aggacaaaac cggtgaacgt cgatttctcc cgattatggc agatagcaag
    38401 caacaaaaga aacatccaat ggaaatcgat cctgatacaa tcgaacaaat ttggggcgaa
    38461 gccgttacaa tctatcgtgc tggtgctgat ttgatgtttg atgaaaatac agaggatgaa
    38521 ctgaatatct accgtgaaca gttcatgtat cgtgatgaag ttgaattaca agtgcttgaa
    38581 tatcttgata tgcccgtccc tgaaaattgg caaaactggt ctattcagca acaacatcaa
    38641 tacacaagta aatatttcga taatagtagc gactttgatc ctggaagcaa aaaactagat
    38701 aaggtctcaa ctcgtgaaat gatgtacaac ttatttatga gaaattcgaa tgacaggaag
    38761 ctgtcaacga agattaacat gatcatggat aatcatcctg attggaaaaa aagtgttttc
    38821 cgggcaggag gtaaaaatac aaaagggttc gtaagagtga agaattcgga aaaaactaat
    38881 cggtagcaat taaaaaatta ttggtagtca tcggtagcag ttgaggggga gatcggtagc
    38941 attctaccga taaaatagga catcggtagc acatcggtag cagtctaacc ccttgatatt
    39001 actgactttt atttaatatt tatatataat gctactcttc tacctatatt tttaaaaaaa
    39061 gtatataaaa taatagtaat aataaagaaa gcctatagaa tagggattct tgaaaaaaac
    39121 tttttacttt ttagaattta tcggtagcac ggtagcagtt tagaaaaaag aggtaaaaat
    39181 gtcatacaca gtaacattat tttttgacaa catggtagac gaaactcact tttttaagaa
    39241 agagagtgat gctgccaaat gcaaggctca gttagaaagc aagtatcgag ggaatcgaat
    39301 gtataaagta aagatggagg agatggagta atgagttatg atttggaaat cttagcgaaa
    39361 atagagagtg gagattatat ttgtattgct gaacctagat atagttctcc gacctacaat
    39421 cttggaaaaa tgtttagggt ggctatggat tgggatttcg accaaggcac aatttacaat
    39481 gttgctgata tttttgaaaa tattaaacgt ggcataactg aattggaaag gcaacctgaa
    39541 aaatatgtac aatatgaacc tgcaaataaa tggggaacga tcaatgatgc gttatatgtt
    39601 ttgagatcgt taagggactg tattttagaa caagatattg atacgaaata tttatatgtg
    39661 aggtggtaaa ttgaaacgac caaacagata cccgtacact aaaaatcaat gggttgaaga
    39721 aaccgttgat cactatactt ataaaaacga tatttgctat acaagtcaca ttttagaaaa
    39781 tagacttact ggagaaatta aggacaagga gttgaagtga tggaagagtt aaagcgaaaa
    39841 gttaatacag tatacaactg gacggtagaa gacgggaagc cgcaacctcc caagcaagat
    39901 ttaccacaag tggtgaaaga ccgggcggac tatttttggg aaatggcaga agatggtatg
    39961 acgtttatgg gagcgatgga atgcatcttc gctgatgaaa agcctacaga ctatgatttg
    40021 ggagctacta aggattggtt gccaaaatct aaggagtttg atgattgggt tggttattcg
    40081 ccaagcatgg ctcaggtagt tattgcagtt tatttgattt atagaggaaa ctaagatgaa
    40141 taagcaggaa ttgattaaaa aattagagga acgaagaaca ataactggga attttcaagg
    40201 ttatgtagtt tggtggaagg atgtaaaaga aatctttgaa caactaggcg aaccgcaacc
    40261 agtcaaagta ccgcagtttg tggcggattg gattagaaaa tgtaaaatgt ttaagcattt
    40321 tgctgtaagt ctatcttttg cattacaacc cattgtatgg gaagaaaatg ggttatctca
    40381 cgagtgcatt gaatggttga tggatgcaaa caatcaagaa ctcttcgcac tagcttggct
    40441 taacggctac gaggtcgaaa aagagaagcg gtattttgtt aagattaaag ggaatattaa
    40501 agaaaatatg ttggtttatg gagaactttt gaaaaggtat ttctttacaa aaagctttag
    40561 tttagacgat gttatatatt cccacacccg taaagaacta gaagacgcaa acttcggctg
    40621 ggtgtttgat tgtgaaggaa ttgatataga ggaggtggag tgatggaaga tgaggaaatc
    40681 ataggcaaca tctacgcaaa cccagagctt ttggaggtca acgagtgaga tattttaaaa
    40741 tcctatgtat tgttttattc gcatccttac tcgtagcatg tcaccagatt tcgagtggga
    40801 cagtggtaga taagtacatt gatgaacctc acacaacgtt catacctgtt ataaatggta
    40861 aaagttcggt acttgtgcca accagaacca aaagaaaata cattctggtc gtttcaggat
    40921 atgcaggtaa taagcaagtt gaagaaaggt ttgaagtgac agcaaatgaa tacaagcact
    40981 atgaaattgg caatactttt atacaggatg ccgttttaga aaataaggag gaggataaat
    41041 aatgagacct aaaaaatacc cacaagatac tcaatagcta ctaaaacaaa aaaagccaag
    41101 acactctctg tctcagcaat aatctcaata atattattat atcacaaagg agacagagag
    41161 tgaacaaggc taaagaacta ttgaaagagt tgcagaatct ggacatggac attcaaagcc
    41221 gtatagatga aattaacgag cttgaggcag gtttgctttc aagccccaag tggattgacg
    41281 tcaaagtcca aggtggtcaa gctagaaaag ttgatgatgt ctatactcag cttgtcgtga
    41341 tgaaagaggc tatagaacag gatactaaag aggttatcaa cagaaagctt gagcttggta
    41401 ggttgattaa caagctgaaa aatccaaaga gcaggtctat tctcagggtg acttacatta
    41461 ctaagatgta tgttgatgat atttgtgaca aaatggaaat cagcagaaca actttctaca
    41521 cttggcggaa tatggctatc tctgaactga atgaggtttt ggagagaatg gaactaaatt
    41581 gaactttaca aaaccgtacg ggaaaaaatg atacttgtta gcacagtttt gtaattctga
    41641 taaaatggta gtatcaagaa ttgaaaagag aggtctcaga attggtagat ggttacctgt
    41701 aatgtcaggg ggctgtaatg gccttggagg ttcaagtcct cccctctcct ttgagtgttt
    41761 gtgtcccaga atgagttaaa tcttctgggt ggggattcac atatcactca ttaacttcta
    41821 tcactcatta acttaaaaat ggttgcagta gcgactgaac cttgcatgat tgcgtagcta
    41881 attatattcc ggataagtta taagctagag ggtttgattc cctcagaggt tgtaaagact
    41941 acaaaaaata aaaatgaagt caaaatttaa tacgcacgca aggtagtagt cgccttgcac
    42001 ttttagggct tagcctagat aatctgtggt aactaaggaa aaggatgttt ttaaatctat
    42061 caaacatcct gccagcaatg gtcaatctaa gcaatgtaat cttaactatt tcagttttgg
    42121 aataggtagg cgaagttaaa gcaggaagat tccaacggca aggtgctgag gaaatgcaaa
    42181 tgtggcagtt tggctgtgag acgagtctat aagaggaatg aggtattcgg tttgaggtgc
    42241 aacaagagct taataccata tcttacaaaa attgggcgcc tcccaaaagt atgtaaggtg
    42301 agtcgattgt ccgcaaaaca atcgataaca agcaggcgct gtgcattttg ttcttcaaaa
    42361 gagaatgaaa cacatggcga tgcgtgtctg tgatagatga aagatgattt ttatatttta
    42421 aggctattca agatagaaaa aactcaaaaa agcaaaagtc atcgcccgtc gtaaacgaaa
    42481 gtgcacttcg gcaattagat tgcctgctca agtctcgcaa ggatgagagt aaagtcaaag
    42541 agtaaagcag cttagacttt tagcggagtc ttcgttaatt gaaaaatggc ctagtagttt
    42601 gcgatgtgag gagtgattgg tctaaccaat cgtgcatgag tgatacaagt aggaatattt
    42661 gtggacaaga taataaacta taagttatca aaagtcactc gtttaaagca gtagtctcat
    42721 gctagttaat ggatacatgg tagacggatt aagtcctgtt tagggaattg aaacgtaggc
    42781 aggttcgaat cctgtcgttc caattgcgat tttaattcgc agagagaggt cttgaaaagg
    42841 tcgcacatcg tgtggctttt tttgattgtt tgaaaggtgg tgatggaaaa ttgaatgaaa
    42901 gacaaaggcg ttttgcagat gagtacatca tctcaggtaa tgcttatcaa tcagctttaa
    42961 gagcaggata tagtgagaaa tatgccaaag caagatcttc tgaattgttg gataatgtcg
    43021 gaatttctga ttacatcaaa aatcgaatgg aggagttgca agatgaaaaa atcttaactc
    43081 aaaaacaaat acttgtgatg ctatcagaaa ttgcgtcggg acaagcgaaa gaaacaatag
    43141 tagtcacaac aaaagtagct gagttgatga ctgatcccgt gactggtaag tctgtaaaag
    43201 tctacaatga aatccctcaa cttgtcgaat acccaacaaa gaacagcgat aggaataaag
    43261 ctcttgaatt gttaggtaaa cgacataaga tgtggacaga caaagtagag gcagacgttt
    43321 ctggaacggt ggtgtttgca aatgagtcag acatatcaga ttaaacagaa cgatattgtt
    43381 gttgacctac ctaagacagt aggagctgga tacggacagt tctggcgctc aagaagtctt
    43441 tatcgtgtag tcaaagggtc ccgtggttcg aagaagtcca agacaaccgc tttgaattat
    43501 gttatccgtc ttttgaagta tccctgggcc aacttgcttg ttattcgtag atactcgaat
    43561 accaacaagc aatcaactta tacggatttt aaatgggcgt gtaatgtgtt gggtgtgact
    43621 catttgttta aatttaacga gtctttgcct gaaataacca taaaagcgac tggtcaaaaa
    43681 atcctattcc gtggtttgga tgatgaactc aaaatcacat ctatcacggt cgatgtcggc
    43741 agtctttgtt gggcatggtt tgaggaagca tatcaaattg agactgaaga caagttcagt
    43801 acagtagttg agtcaatccg tggtagctta gatgtacctg atttctttaa acaaatcaca
    43861 gtcacattta acccgtggaa tgagaggcac tggctcaaac gtgtgttctt tgatgaagag
    43921 actagccgag ctgatacatt cgctactaca accacttaca aatgcaatga gtggcttgat
    43981 gaagtcgata ttaagcgcta tgaggacttg tatcacacaa atccaaggcg tgcgagaatc
    44041 gtttgtgatg gtgaatgggg agttgctgaa ggtttaatct atgagaacgt gaccgtcaag
    44101 gatttcgata aggatgaatt gctacgagat tcagctaata agttatgtat cggtcttgac
    44161 tttggtttta ctcacgatcc aaccgctttg tgttgttcgt tgataaatga cacgacgaaa
    44221 gagatttatg tctttgatga ggcgtataaa gttgggttga taacaaaaga agttgcgaag
    44281 atgataaaag acaaaggtta tcatcgttca caaatcgttg ccgatagtgc tgaattgcga
    44341 ctgattgagg aactaaggtc agagcatggt ataactcgaa ttaaagagag tcgtaaaggt
    44401 aaggatagta ttatggcagg cgtatccaaa ttgcaaggat acgctattta tgtgcatcca
    44461 gattgtaaaa acatcatgga tgaattttat agttactgct accagcgaga taaagaaggc
    44521 aactggttga ataaaccaga ggataaaaac aaccacttga tggacgcttt gcgttacagc
    44581 cttcaatgta tcgaaggtgg aaaagcaacc gtccgcagac gttctgatta tggtctatag
    44641 agaggaaaga catgtaccaa tatttaacct atccacggga tggatatgat gagggttctt
    44701 tgaagaaaga cctgatttac aaattgataa cgatacataa cactgaaagc tcacgcttga
    44761 agaatttaaa aagctactac atgggtgatc atgctatttt aaatcacaag agacgcaacg
    44821 tgaacgcacc gaattacaag acggtagcta atcatgccaa ggatatcgca gacacggcta
    44881 caggctattt tatgggcaat cctattaagt ataacaatac tgctgacagt gatatcgatg
    44941 aactacttac agcctttgat ggtgctgaga ttgaccaagt agatgctcag aatgctttga
    45001 acatggctat ctatggtcgt gcttacgagt acatctatgc taaagagggt atgactgagt
    45061 tggattcaac tagtattgat ccagaaaata ccttcatggt ctacgatgat agtattgagc
    45121 ggaagccttt gtttgcggtc tattactatg aagtaaaaga cgatacgaaa gacactacca
    45181 agtaccaggc tgaggtcttt accgaaaatc tgcactatca catggtgctg agaagtacag
    45241 attcaggaac aactcagaat gagcaggtaa cccctcacaa ccttgggcaa atcccaatta
    45301 tcgaatatcg caacaatcac tttgcgatcg gtgactatga gcaacaaatt agcttgatag
    45361 acgcttataa ttccttgatg gggaatcgtg tcaatgataa ggaacaggct gtagagtcta
    45421 tccttgtctt gtatggcacg cagttagcag acactccaga agacgctaag gtagcgatga
    45481 agattctttc tgaagaaggt cttttggaat taccgggcga tagtgcaaga gctgagttct
    45541 tgaagaacac gttggacgaa agtgctactg aaatcttgcg tacagctctt aaagaggaca
    45601 tctacacatt tagccatgtg cctaatttga ctgatgagaa tttcgcaggg aatacatcag
    45661 gcgtagccat ggaatttaag ctgatgggcc ttgagatgat tactaagacc aaggaagcga
    45721 actataagcg aggattgcgt cagcgtattg cgatttttgc tcattacttg ggtatgaaac
    45781 agattgcact agagtctcat tcaatcgttc cacaattcag tcgtggtttg cctaagaact
    45841 tgttagaaat ctctcagatc gtgaacaacc ttgaaggtaa agtgacgaat agacagctta
    45901 tttctctctt gccgtttgtg gaagaccctg acgctgaact ggaagccttg gaagaagaaa
    45961 aaaagaagaa catggaagac atgccgatgt tcaacaaaga caacacgaaa cccgaagacg
    46021 aggtagagga tgaagaatca ggagtattgg gcgaagagga aagccaatct gatttaccag
    46081 cagatggaca aggccgaaaa gcaggcagac cagttcgata aggtctatca ggaagccaag
    46141 acttacttgg ataaggaagt caataagatt tttgataagt tccaacgtga ttatggtcta
    46201 agtcaggtag aagctagaca agtcttgaag aacatgaaag acaagaaaaa tctgaatgaa
    46261 cttcgtaaag tgcttgaagc aagaccgaat gatccaaata ttcaaagact actggctgac
    46321 ttagatagtc cggcttattc tttccgtatg aagcgtctag aacgtttgag tgatgattta
    46381 gaccgtatgc gtgaatctat ctatcattca gaaaagacag gctcagacgc cttttatagc
    46441 gacctgatga aggatagtta ctacaaggct acctttgacc tgcagcagca gacaggacta
    46501 gcatacggct tttctgggct tcctgagagc gagattaaac atctacagtc tttcagttgg
    46561 gtaggtgacg gaagtaccta ctctacagac atctggaaga atacggggaa gcttacttct
    46621 agcataaaag atgaactact tatgagcctc atgacaggcc gagatacacg agaaactgca
    46681 caagcaattg ctgagaggtt caatgtaggt cagaatgatg caaggcgttt ggttcggacg
    46741 gaatcagcct tttttcataa ccaaatggaa ctactcagct atgaagaagc agacatagaa
    46801 aagtatatct ttgtggccgt cttagacaag cgcacatcac gcatttgtca agaacatgac
    46861 aatcaggtct atgataggga taaggctgtc cctggtgtca attgtccacc tatgcaccct
    46921 tggtgtaggt ctactactgt cgcatacgac gaggacgcag actacagcaa gttgaagcgc
    46981 agagcaagga atccagtgac aggtaagacc gagctggtgc ctgctgatat gacttataaa
    47041 gagtggtata gcaagtatgt tgcgaaagac ggggaaaagg tgtataatca agatacaaga
    47101 gaagccaagg cgaaatttta tagcgaacaa ctattgtcca aaatttcagg agttgagcca
    47161 aaaattacaa gtgatatgca acgtatcgca ggagaaaaca aattggcagg tcttgaattt
    47221 aggaagaaaa cagttgagtc gttatcacgt aaaattattg cagatagcct agttgaaaat
    47281 ataagtttgt caaaagccgt gagtaagatt aatgacgcct taaggtacac aactattttc
    47341 gattccgata cttttacaga agagtatttg aagatgaaac agaagcttgt cgcagaaggt
    47401 tataaaattg taaaagtaaa aaacacttgg ttagtagatg gaccatacaa aggtgtgaat
    47461 acagtcgttg aaaaagatgg tatcaacttt gaaatgcagt atcatactca ggaaagtttc
    47521 gacttaaaaa atggttcatt acatgaactc tatgagaagt atcgtgatac gaatacatct
    47581 gatctagaac gcatgaaatt atttaaggaa atgcttgatt taagcaatgg gcttgagatt
    47641 cctaaaaata tagagagggt gaagtgatgt gaaagatatt aaatactacc gcacaacgac
    47701 gaacaatgct caagtacttc gtttgattga tggtgtcatg caagtttttg acattgaaaa
    47761 aaagtgggtt aatagcatag attggtttaa taaaatcttt tttaatgact ttacggattt
    47821 tgaagaaatt tcagaaaatg atgcatttac ttatattgac aggatggtag cggcatgatt
    47881 gatattgctt tggctatcgc taaaaaagca catgcagggc aggtagataa agcggatgtt
    47941 gattacatac agcatcctct ctatgtggcc agtcaagtca aaactgaaca agaaaaagct
    48001 gtcgctcttt tacatgatgt gattgaggat agcgatataa ctgctgccga tttattggcg
    48061 tctggtttgt caaatgaagt tgttacagcg gtacaaattt tgacaaagaa aaaaggtcaa
    48121 agttatcaag aatatcttgg gaaagtaaaa tcaaataatt tagcaagagt tgtaaaactt
    48181 gcagatttga aacacaactc agatttatca cgtttgaaat ctgttaccaa tacagactac
    48241 gagcgtgtta aaaaatataa aaatgcaatt tatt
//
LOCUS       DBEROT010000011        48212 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.11, whole genome shotgun sequence.
ACCESSION   DBEROT010000011 DBEROT010000000
VERSION     DBEROT010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.11"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            9..89
                     /locus_tag="ACL8CG_000761"
     tRNA            9..89
                     /locus_tag="ACL8CG_000761"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="ACL8CG_000762"
     tRNA            94..164
                     /locus_tag="ACL8CG_000762"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="ACL8CG_000763"
     tRNA            179..251
                     /locus_tag="ACL8CG_000763"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            262..333
                     /locus_tag="ACL8CG_000764"
     tRNA            262..333
                     /locus_tag="ACL8CG_000764"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:294..296,aa:Gln,seq:ttg)
     gene            343..426
                     /locus_tag="ACL8CG_000765"
     tRNA            343..426
                     /locus_tag="ACL8CG_000765"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:377..379,aa:Leu,seq:caa)
     gene            533..1810
                     /locus_tag="ACL8CG_000766"
     CDS             533..1810
                     /locus_tag="ACL8CG_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGS1343397.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VEERFSIYMEAIQKKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1886..3370
                     /gene="thrC"
                     /locus_tag="ACL8CG_000767"
     CDS             1886..3370
                     /gene="thrC"
                     /locus_tag="ACL8CG_000767"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGS1343398.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3431..4711
                     /locus_tag="ACL8CG_000768"
     CDS             3431..4711
                     /locus_tag="ACL8CG_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS1343399.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4715..5335
                     /locus_tag="ACL8CG_000769"
     CDS             4715..5335
                     /locus_tag="ACL8CG_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1343400.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5501..6643
                     /locus_tag="ACL8CG_000770"
     CDS             5501..6643
                     /locus_tag="ACL8CG_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS1343401.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDVQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAKKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVAERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6966..7390
                     /locus_tag="ACL8CG_000771"
                     /pseudo
     CDS             6966..7390
                     /locus_tag="ACL8CG_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            7401..7769
                     /locus_tag="ACL8CG_000772"
     CDS             7401..7769
                     /locus_tag="ACL8CG_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGS1343402.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            7876..8493
                     /locus_tag="ACL8CG_000773"
                     /pseudo
     CDS             7876..8493
                     /locus_tag="ACL8CG_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(8520..9377)
                     /locus_tag="ACL8CG_000774"
     CDS             complement(8520..9377)
                     /locus_tag="ACL8CG_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGS1343403.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9507..10649
                     /gene="tgt"
                     /locus_tag="ACL8CG_000775"
     CDS             9507..10649
                     /gene="tgt"
                     /locus_tag="ACL8CG_000775"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGS1343404.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLSSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            10750..12567
                     /locus_tag="ACL8CG_000776"
     CDS             10750..12567
                     /locus_tag="ACL8CG_000776"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS1343405.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKIANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12720..13871
                     /gene="nagA"
                     /locus_tag="ACL8CG_000777"
     CDS             12720..13871
                     /gene="nagA"
                     /locus_tag="ACL8CG_000777"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGS1343406.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14034..15092
                     /locus_tag="ACL8CG_000778"
     CDS             14034..15092
                     /locus_tag="ACL8CG_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGS1343407.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15243..15608
                     /locus_tag="ACL8CG_000779"
     CDS             15243..15608
                     /locus_tag="ACL8CG_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGS1343408.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15684..16625
                     /gene="comGA"
                     /locus_tag="ACL8CG_000780"
     CDS             15684..16625
                     /gene="comGA"
                     /locus_tag="ACL8CG_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGS1343409.1"
                     /translation="MVQEIAQEIIRSAREKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYGNLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16573..17589
                     /gene="comGB"
                     /locus_tag="ACL8CG_000781"
     CDS             16573..17589
                     /gene="comGB"
                     /locus_tag="ACL8CG_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGS1343410.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMKSLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17591..17914
                     /gene="comGC"
                     /locus_tag="ACL8CG_000782"
     CDS             17591..17914
                     /gene="comGC"
                     /locus_tag="ACL8CG_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGS1343411.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQDDGRITEEQAKAYKEYHDKQNTS
                     QIVKD"
     gene            17877..18311
                     /gene="comGD"
                     /locus_tag="ACL8CG_000783"
     CDS             17877..18311
                     /gene="comGD"
                     /locus_tag="ACL8CG_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGS1343412.1"
                     /translation="MINKILVKSLKIKAFTMLESLLVLGLVSILALGLSGSVQSTFAA
                     VEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPVPKGIQAPSGQSI
                     TFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18274..18576
                     /gene="comGE"
                     /locus_tag="ACL8CG_000784"
     CDS             18274..18576
                     /gene="comGE"
                     /locus_tag="ACL8CG_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGS1343413.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18539..19000
                     /gene="comGF"
                     /locus_tag="ACL8CG_000785"
     CDS             18539..19000
                     /gene="comGF"
                     /locus_tag="ACL8CG_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGS1343414.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            18978..19424
                     /gene="comGG"
                     /locus_tag="ACL8CG_000786"
     CDS             18978..19424
                     /gene="comGG"
                     /locus_tag="ACL8CG_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGS1343415.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFSSVK
                     IKEEKTDKKEEVVTDSSEKAEKKNQKRSLKRKRIHSQFNYNALNPE"
     gene            19527..20119
                     /locus_tag="ACL8CG_000787"
                     /pseudo
     CDS             19527..20119
                     /locus_tag="ACL8CG_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20180..21133
                     /locus_tag="ACL8CG_000788"
     CDS             20180..21133
                     /locus_tag="ACL8CG_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1343416.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21184..22374
                     /locus_tag="ACL8CG_000789"
     CDS             21184..22374
                     /locus_tag="ACL8CG_000789"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGS1343417.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22375..22506
                     /locus_tag="ACL8CG_000790"
     CDS             22375..22506
                     /locus_tag="ACL8CG_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343418.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            22523..22894
                     /gene="rnpA"
                     /locus_tag="ACL8CG_000791"
     CDS             22523..22894
                     /gene="rnpA"
                     /locus_tag="ACL8CG_000791"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGS1343419.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22869..23693
                     /locus_tag="ACL8CG_000792"
     CDS             22869..23693
                     /locus_tag="ACL8CG_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS1343420.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23712..24698
                     /gene="jag"
                     /locus_tag="ACL8CG_000793"
     CDS             23712..24698
                     /gene="jag"
                     /locus_tag="ACL8CG_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGS1343421.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24749..25372
                     /locus_tag="ACL8CG_000794"
     CDS             24749..25372
                     /locus_tag="ACL8CG_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGS1343422.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKILDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25503..26960
                     /locus_tag="ACL8CG_000795"
     CDS             25503..26960
                     /locus_tag="ACL8CG_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1343423.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            26983..27261
                     /locus_tag="ACL8CG_000796"
     CDS             26983..27261
                     /locus_tag="ACL8CG_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1343424.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQAL"
     gene            27341..27826
                     /locus_tag="ACL8CG_000797"
     CDS             27341..27826
                     /locus_tag="ACL8CG_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1343425.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27843..28508
                     /locus_tag="ACL8CG_000798"
     CDS             27843..28508
                     /locus_tag="ACL8CG_000798"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGS1343426.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRRITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28512..29375
                     /locus_tag="ACL8CG_000799"
     CDS             28512..29375
                     /locus_tag="ACL8CG_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGS1343427.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            29377..30081
                     /locus_tag="ACL8CG_000800"
     CDS             29377..30081
                     /locus_tag="ACL8CG_000800"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGS1343428.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30260..31933
                     /locus_tag="ACL8CG_000801"
                     /pseudo
     CDS             30260..31933
                     /locus_tag="ACL8CG_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
     gene            32045..33136
                     /gene="ulaG"
                     /locus_tag="ACL8CG_000802"
     CDS             32045..33136
                     /gene="ulaG"
                     /locus_tag="ACL8CG_000802"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGS1343429.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33250..35226
                     /gene="tkt"
                     /locus_tag="ACL8CG_000803"
     CDS             33250..35226
                     /gene="tkt"
                     /locus_tag="ACL8CG_000803"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS1343430.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35343..35642
                     /gene="yajC"
                     /locus_tag="ACL8CG_000804"
     CDS             35343..35642
                     /gene="yajC"
                     /locus_tag="ACL8CG_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS1343431.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35689..36117
                     /locus_tag="ACL8CG_000805"
     CDS             35689..36117
                     /locus_tag="ACL8CG_000805"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGS1343432.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36119..36529
                     /locus_tag="ACL8CG_000806"
     CDS             36119..36529
                     /locus_tag="ACL8CG_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGS1343433.1"
                     /translation="MENLTNFYEKYRVYLTRPRLEILAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36829..39480
                     /gene="adhE"
                     /locus_tag="ACL8CG_000807"
                     /gene_synonym="adhC"
     CDS             36829..39480
                     /gene="adhE"
                     /locus_tag="ACL8CG_000807"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGS1343434.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40347..40655)
                     /locus_tag="ACL8CG_000808"
     CDS             complement(40347..40655)
                     /locus_tag="ACL8CG_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1343435.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(40652..40960)
                     /locus_tag="ACL8CG_000809"
     CDS             complement(40652..40960)
                     /locus_tag="ACL8CG_000809"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1343436.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALEWIGEIR
                     "
     gene            complement(40965..42260)
                     /locus_tag="ACL8CG_000810"
     CDS             complement(40965..42260)
                     /locus_tag="ACL8CG_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS1343437.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42278..43687)
                     /locus_tag="ACL8CG_000811"
     CDS             complement(42278..43687)
                     /locus_tag="ACL8CG_000811"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS1343438.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKKEYGNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKRS
                     GRWYRKVSDNNGFEVEIEE"
     gene            43845..44573
                     /locus_tag="ACL8CG_000812"
     CDS             43845..44573
                     /locus_tag="ACL8CG_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1343439.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45032..45226
                     /locus_tag="ACL8CG_000813"
     CDS             45032..45226
                     /locus_tag="ACL8CG_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS1343440.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRKLFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(45348..45514)
                     /locus_tag="ACL8CG_000814"
                     /pseudo
     CDS             complement(45348..45514)
                     /locus_tag="ACL8CG_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(45592..46902)
                     /locus_tag="ACL8CG_000815"
     CDS             complement(45592..46902)
                     /locus_tag="ACL8CG_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGS1343441.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47139..48011
                     /gene="nadC"
                     /locus_tag="ACL8CG_000816"
     CDS             47139..48011
                     /gene="nadC"
                     /locus_tag="ACL8CG_000816"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGS1343442.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            48142..>48212
                     /locus_tag="ACL8CG_000817"
     CDS             48142..>48212
                     /locus_tag="ACL8CG_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS1343443.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEA"
BASE COUNT        14737 a         8582 c        10528 g        14365 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttggggtata gccaagcggt aaggcaaggg actttgactc
      301 cctcatgcgt tggttcgaat ccagctaccc cagttactat ttgccggcgt ggcggaattg
      361 gcagacgcgc tggactcaaa atccagtgtc cgcaaggacg tgccggttcg accccggccg
      421 ccggtatagt atagtgttag gaacgttgtt attcttcgtt ccttttttat attatttttg
      481 gtataattat agttattcaa attttattta gattaagaaa gtgtagggta gtatgtcttg
      541 ttctatcgat ttattaaaac atcggtattt gaaaaatatt aaagaaaatc ctgaattgtt
      601 tgtcggaatt gagttggagt atcctgttgc aagtttagaa ggggatgcta cagatgttga
      661 agttataaag gatctatttc attatttagt ttctactttg gatctcaccg tagcaaaggt
      721 agatgatttt ggcaatttga tccagttagt agatccgata agtcaggatg ctattttatt
      781 tgaagtttcc tatacaacga ttgagtttgc atttggtaag gctgaaacga tacaagaagt
      841 tgaagaacgt tttagtattt atatggaagc aatccagaag aagttagctg aatcaaatca
      901 tgctattgtt ggctgtggta tccatcccaa ctgggataaa aatgagaatt gtccagtggc
      961 ttatccacgc tatcagatgt tgatggatta tttgaatttg agtagaaata ttattaaatc
     1021 agatttacat catttccctg aatatggtac ttttatctgt gggagccagg ttcagctgga
     1081 tatttcaaaa accaactact tacgggtgat taatgctttt actcaaattg aagcggctaa
     1141 ggcttattta tttgcaaact ctgagttttc gggtgcggat tgggatacga aaatttcaag
     1201 ggatattttc tgggaagaat ctatgcatgg tatctatcca gagaatgttg gggtcaatgc
     1261 tagactcctt aatgatgaag ctgatttttt tgactatcta aatcattctg cgatttttac
     1321 tgcggaacgt gatgggcaga cctattattt ttatcctatt caggctgggg actatttggc
     1381 tacgcctgaa atccaagcat ttgctctgaa tggggatgag gttattattt ccccccaaga
     1441 gaaggatttt gaaactcatc gtagttacca gtaccaagac ttaacgactc gaggaacagt
     1501 tgagtttcgt agtgtgtgta cacagccact tgataggact tttgcttctg cagcttttca
     1561 cttgggatta ttggttaatt tagacaagtt agaagcttac ttagaaacag cacctttctt
     1621 taaagtattt ggttatgatt acaagtcttt aaggagacaa ttttctaaga aaaatcttac
     1681 agatgaggaa gaaactacga ttattgaatt ttccaaagac ttactcctac tagctgagga
     1741 gggactagtg gtgagaaata aggaagaaat gacctattta cagcctttga gagaagaatt
     1801 gagcctataa tttctcttat aaagggagaa ttttctgaaa aatcatgata taatggacga
     1861 gactatagat aaaggataga gagtaatgac attagtttat caatcaacgc gtgatgccaa
     1921 caatacagta actgccagcc aagcaatttt gcaaggtttg gcgacggacg gcggtttgtt
     1981 tacaccggtt acttatccaa aggtagattt gaactttgac aaattgaaag atgcttctta
     2041 ccaggaagtt gctaagctag ttttgtcagc atttttagat gactttacag ctgaggagtt
     2101 ggactactgt atcaacaatg cctacgatag caaatttgat actccagcta ttgcaccatt
     2161 agtgaaatta gatgggcaat acaatttgga acttttccat ggttcaacga ttgcctttaa
     2221 ggatatggcc ttgtctattt tgccatactt tatgacgact gctgctaaga aacatggttt
     2281 ggagaacaag attgttatct tgacagcgac atctggtgac acggggaaag ctgctatggc
     2341 ggggtttgcg gatgtgcctg gtactgagat tatcgtcttt tatccaaagg gtggtgtcag
     2401 caaggtacaa gagttgcaaa tgaccactca gaatggtgac aatactcatg ttatcgctat
     2461 agatggtaac tttgacgatg cacaaaccaa cgtgaagcac atgtttaacg acgtggctct
     2521 tcgtgaaaga ttagcggcca acaagttgca attttcatct gctaactcta tgaatatcgg
     2581 tcgtttggtg ccacagattg tttattatgt ttatgcctat gctcagttgg tcaagactgg
     2641 tgagatcgtg gctggtgata agattaactt cacagtacca acaggaaact ttggaaatat
     2701 cttggctgcc ttttatgcca aacaaatcgg tctcccagtt ggtaaattaa tctgtgcttc
     2761 aaatgacaac aatgttttga cagacttctt taaaacacgt gtctatgaca aaaaacgtga
     2821 gtttaaggta acaaccagcc catctatgga tatcttggta tcttcaaact tggagcgctt
     2881 gattttccat cttttgggaa ataatgctga aaagacaact gaacttatga atgccttgaa
     2941 cacgcaagga caatataagt tgacagactt tgatgcagag attttggacc tctttgcagc
     3001 tgaatatgcg actgaggaag aaacggcagc agagatcaag cgtgtttgtg agttagattc
     3061 ttatatcgag gaccctcata cagctgttgc ttcagcagtt tataaaaaat accaatcggc
     3121 cactggagat gtaactaaga cagtgattgc ttcaacagct agtccataca agttcccagt
     3181 agttgcagta gaagctgtaa ctggaaaagc aggtttaaca gactttgaag ccttggctca
     3241 attacatgaa atctcaggcg ttgcagtgcc accagcagtt gatgggcttg aaatagctcc
     3301 aattcgtcac aagacaacag tggcagctgc tgacatgcaa gcagcggttg aggcttattt
     3361 aggactttaa gacagaggga gcaaactcgg ttgggaaacc aactgagttt cttttcatca
     3421 ggaggagaga ttgtttaaga aaaataaaga cattcttaat attgcattgc cagctatggg
     3481 tgaaaacttt ttgcagatgc taatgggaat ggtggacagt tatttggttg ctcatttagg
     3541 attgatagct atttcagggg tttcagtagc tggtaatatt atcaccattt atcaggcgat
     3601 tttcatcgct ctgggagctg ctatttccag tgttatttca aaaagcatag ggcagaaaga
     3661 ccagtcgaag ttggcctatc atgtgactga ggcgttgaag attaccttac tattaagttt
     3721 ccttttagga tttttgtcca tcttcgctgg gaaagagatg ataggacttt tggggacgga
     3781 gagggatgta gctgagagtg gtggactgta tctatctttg gtaggcggat cgattgttct
     3841 cttaggttta atgactagtc taggagcctt gattcgtgca acgcataatc cacgtctgcc
     3901 tctctatgtt agttttttat ccaatgcctt gaatattctt ttttcaagtc tagctatttt
     3961 tgttctggat atggggatag ctggtgttgc ttgggggaca attgtgtctc gtttggttgg
     4021 tcttgtgatt ttgtggtcac aattaaaact gccttatggg aagccaactt ttggtttaga
     4081 taaggaactg ttgaccttgg ctttaccagc agctggagag cgacttatga tgagggctgg
     4141 agatgtagtg atcattgcct tggtcgtttc ttttgggacg gaggcagttg ctgggaatgc
     4201 aatcggagaa gtcttgaccc agtttaacta tatgcctgcc tttggcgtcg ctacggcaac
     4261 ggtcatgctg ttggcccgag cagttggaga ggatgattgg aaaagagttg ctagtttgag
     4321 taaacaaacc ttttggcttt ctctgttcct catgttgccc ctgtccttta gtatatatgt
     4381 cttgggtgta ccattaactc atctctatac gactgattct ctagcggtgg aggctagtgt
     4441 tctagtgaca ctgttttcac tacttgggac ccctatgacg acaggaacag tcatctatac
     4501 ggcagtctgg cagggattag gaaatgcacg cctccctttt tatgcgacaa gtataggaat
     4561 gtggtgtatc cgcattggga caggatatct gatggggatt gtgcttggtt ggggcttgcc
     4621 tggtatttgg gcagggtctc tcttggataa tggttttcgc tggttatttc tacgctatcg
     4681 ttaccagcgc tatatgagct tgaaaggata ggaaatgcaa aaaacagctt ttatttggga
     4741 tttagacggg actttattgg actcttacga agcgatttta tcagggattg aggagacttt
     4801 tgctcagttt tctattcctt atgataagga gaaggtgaga gagtttatct tcaagtattc
     4861 ggtgcaagat ttgcttgtgc gggtggcaga agatagaaat ctggatgttg aggtgctaaa
     4921 tcaggtgcgt gcccagagtc tggctgagaa gaatgctcag gtagttttga tgccaggtgc
     4981 gcgtgaggtg ctagcttggg cagacgaatc aggaattcag cagtttatat atactcataa
     5041 ggggaacaac gcttttacca ttctcaagga cttgggggtg gaatcctatt ttacagagat
     5101 tttaaccagt cagagtggct ttgtgcggaa gccaagtcca gaagcggcta cctatctgct
     5161 agataagtat cagttgaatt ctgataatac ttattatata ggggatcgga ctctggatgt
     5221 ggaatttgcc cagaatagtg ggattcaaag tatcaacttt ttagagtcta cttatgaagg
     5281 gaatcacagg attcaagcgt tagcagatat ttcccgtatt tttgagacta agtgataaaa
     5341 agattgtgtc agttttgtga cagagaccta acaaactatt tcaagtaacc tagtttgtta
     5401 caaggaatag acagttctgt taaataggcc cgagagggct ttttttctac attttttgtg
     5461 ttatgataga caggtactca tttgaaagga atttgaaaga atgaagaaaa gaatgttatt
     5521 agcgtcaaca gtagccttgt catttgcccc agtattggca actcaagcag aagaagttct
     5581 ttggactgca cgtagtgttg agcaaatcca aaacgatttg actaaaacgg acaacaaaac
     5641 aagttatacc gtacagtatg gtgatacttt gagcaccatt gcagaagcct tgggtgtaga
     5701 tgtcacagtg cttgcgaatc tgaacaaaat cactaatatg gacttgattt tcccagaaac
     5761 tgttttgaca acgactgtca atgaagcaga agaagtaaca gaagttgaaa tccaaacacc
     5821 tcaagcagac tctagtgaag aagtgacaac tgcgacagca gatttgacca ctaatcaagt
     5881 gaccgttgat gttcaaactg ttcaggttgc agacctttct caaccgattg cagaagctcc
     5941 aaaagaagta gcatcaagtt cagaagttac aaagacagtg attgcttctg aagaagtggc
     6001 accatctacg ggcacttctg tcccagagga gcaaacggcc gaaacaactc gcccagttga
     6061 agaagcaact cctcaggaaa cgactccagc taagaagcag gaaacacaag caagccctca
     6121 agctgcatca gcagtggaag caactacaac aagttcagaa gcaaaagaag tagcatcatc
     6181 aaatggagct acagcagcag tttctactta tcaaccagaa gaaacgaaag taatttcaac
     6241 aacttacgag gcaccagctg cgcccgatta tgctggactt gcagtagcaa aatctgaaaa
     6301 tgcaggtctt caaccacaaa cagctgcctt taaagaagaa attgctaact tgtttggcat
     6361 tacatccttt agtggttatc gtccaggaga cagtggagat cacggaaaag gtttggctat
     6421 cgactttatg gtagcagaac gttcagaatt aggggataag attgcggaat atgctattca
     6481 aaacatggcc agccgtggca ttagttacat catctggaaa caacgtttct atgctccatt
     6541 cgatagcaaa tatgggccag ctaacacttg gaacccaatg ccagaccgtg gtagtgtgac
     6601 agaaaatcac tatgatcacg ttcacgtttc aatgaatgga taaacccgac ttgataacat
     6661 cattttgacg aatgagatct agctttcgtg atggaaagcg attctcgttc gttttttctt
     6721 tgtcatactc ttcgaaaatc tcttcaaacc acgtcagttt tatatgaaac ctcaaagctg
     6781 tgctttgagc aacctgcgac tagcttccta gtttgctctt tgattttcat tgagtatcaa
     6841 tttgaatgga aaatgggaag ttaccatatt gtaatgagtt aagtaacatt cttgcaatct
     6901 attttacttt gcattatacg tgattagtca aatattgata aatcaataaa aagagagggg
     6961 aagaaatgct agagattcaa gatttactgt atcaactccg cttgtctgag caagcgagta
     7021 cgcaattgtt tgaaaaaagg cttggattag tttgacacgg tatcagattt tactgttttt
     7081 gctggagcat tctccttgta accaaatggc ggttcaggag cgtttgaaaa ttgatcaggc
     7141 tgctttgaca cggcatttca agattttgga aacggaaggt ttggtggagc gtcatcgtaa
     7201 tcctgaaaat cagcgggaag tgttggtaga gactgcgaag tatgccaagg agcagttagt
     7261 ggtgaatccc cctctgcaac atatcaaggt taaggaagag atggaaagta tcttaacaga
     7321 gtttgagaga acagaactca gccgtttatt aaataaattg gttttgggta ttgaaaatat
     7381 agaaatttaa ggagaaatag atgtcaatta ttacaattat tttaacaacg atcgttgctt
     7441 tggagcattt ttacattttt tatttggaaa gtattgccac gcaatcagat gcgactagtc
     7501 gtgtatttaa tatggaaaag gaagaattgg ctcatccgtc agtaagttca ttgttcaaaa
     7561 atcaagggat ttataaggct ctgctaggag tctttctctt gtatgtcatt tatttctcac
     7621 agaatttaga aattgtgact atttttgtct tatttgtgat tggtgctgcg acttacggct
     7681 ctttaacagc ggataaaaaa attattttga aacaaggtgg atcagctatt ttggccttga
     7741 ttagtatttt actctttaaa tacacttgaa ggtcgattct aatctcgcta atccttttta
     7801 atccagaata agggaaatat gttatacttg tttttaagaa aaaagtttca ttgaattggt
     7861 tttgaggagt tagaaatgaa agtattagtg acaggttttg agcccttttg aggccattaa
     7921 aggtttacca gctgaaatcc atggtgctga ggtccgttgg ctagaggtgc cgacagtttt
     7981 tcacaaatct gctcaagtat tggaagaaga gatgaatcgt tatcaacctg actttgtcct
     8041 ttgtattggg caagctggtg gaagaactag tttgacacct gaacgagtgg ccattaatca
     8101 agacgatgca cgcatttctg ataacgaaga taatcaaccg attgaccgtc ccattcgccc
     8161 agatggtgct tcggcctact ttagtagttt gccgattaaa gcgatggttc aagctataaa
     8221 aaataaggat taccggcctc tgtttccaat acggcaggga cttttgtctg cagccatttg
     8281 atgtatcagg ctctctattt ggtagaaaag aaatttccat atgttaaggc aggttttatg
     8341 catattcctt atatgatgga acaggtggtg aacagaccga ctactccaac tatgagttta
     8401 gtggatattc ggcgagggat agaagcagca atcggcgcta tgatagaaca tggagatcag
     8461 gaactcaagt tggtaggcgg agaaattcat tgatagaaaa aagcttgagg ggaaaacctt
     8521 caagcttttg gacgttttcg agccaatact gctcggtaaa acataatttt agtgcattgg
     8581 atataaggta ggagtgaaaa actagcaatg ccaaaggtaa tccaattgag gaagtaccaa
     8641 ggaagaagct gtaaatctag gacaaagtgc tggaacttgt agcccttcat aaaggaacgg
     8701 ctagttttta ggattcgtct tggtgggacc tgtcctaggt ctaaactata acagagaaga
     8761 aattccacct gtgaataggc ataatactgt ggaatataga ggatatttcc tacaatgatc
     8821 aagatgagac ttgcaagaaa gtagagtcca aagaccatga ggaaacgctc ggtttcaact
     8881 gatgagagat ctagatttgg aaactcagga tgtagggtga cgaatttttt ggctaaaaag
     8941 ctactataaa agaggaggta aatcccaagt aaattaggga tactccataa aaagagatag
     9001 aaacgtttga gaagtagggt caaaaaggtt tgagaaaagc gctcctcatc aaagagagct
     9061 aggctgtttt ttacagatgg ctccgtttta gaatctttca tgagtgtcag tgttgcatag
     9121 acggaactgg tcaaaagaat agtcccgata aaggagacta gtagaggaaa gaggtaggtt
     9181 tgaagtattt ggccaagtat gctgaaaaat ggctgttcta aaacagtccc gtggatccga
     9241 gataagggat taagaaaacc agataagatg accagcatac tgggaaggat atagaggaga
     9301 aagagacggg gggtgtcagc ctgaaaatgt tttgactcct gacgaattgt ttttaaatca
     9361 atttttggat agttcattct cttattatac catagttctt atacatagtt cgtgacagtt
     9421 cctacttttt ttgataaaat catacagtgt gtccttgggc acactgtatg aactgggact
     9481 gtctttccca gcttcggagg taaaaaatgt cagattcacc aatcaaatat cgtttgatta
     9541 agaaagaaaa acacacagga gctcgtctag gagaaatcat cactccccac ggtacctttc
     9601 cgacacctat gtttatgcca gttgggacac aagccactgt caaaactcag tcacctgaag
     9661 aattgaagga gatgggttcg ggaattatcc tatcaaacac ctatcatctc tggcttcgcc
     9721 ctggagatga actcattgca cgcgctggtg gtctccacaa gttcatgaat tgggaccagc
     9781 ctatcttgac agatagtggt ggttttcagg tttattcttt agcagatagc cgtaatatca
     9841 cagaagaagg agtaaccttt aaaaatcatc taaatggttc taagatgctc ctatccccag
     9901 aaaaagccat ctctattcag aataatctga gttcagacat catgatgtcc tttgatgaat
     9961 gtcctcagtt ttatcaacct tatgactacg ttaagaaatc gatcgagcgt accagccgtt
    10021 gggctgagcg tggtttgaag gctcaccgtc gtccacatga ccaaggtttg tttggaattg
    10081 tgcaaggtgc aggatttgaa gaccttcgcc gccaatcagc tcacgatctt gtcagcatgg
    10141 atttctcagg ctactctatc ggtggtttgg cagtgggaga aacccatgaa gagatgaatg
    10201 cggtcttgga ctttacaact caactgctgc ctgaaaataa acctcgttat ctgatgggtg
    10261 tgggagcgcc agatagcttg atcgatgggg tcattcgtgg ggtggatatg tttgactgtg
    10321 tcttaccgac tcgaattgct cgtaacggga cttgtatgac cagtcaagga cgtttggttg
    10381 tgaaaaatgc ccagtttgct gaggacttta cgccactgga tcctgagtgt gattgctaca
    10441 catgtaataa ctatacacgc gcttaccttc gtcacctgct caaggctgat gaaacctttg
    10501 gtatccgctt gactagctac cacaatcttt acttcttgct taacctgatg aagcaagtgc
    10561 gacaagccat catggatgac aatctcttgg aattccgtaa gtattttgtg gaaaaatatg
    10621 gctataataa gtcaggacgt aatttctaaa atggaattga tataagctaa aaatcctaag
    10681 ttttctctta ggatttttct tctttttttg atagaataaa gtgtacaatg aaaggaagaa
    10741 taaactcgta tgcgcattaa atggttttcc ttgattagga ttataggttt acttttggta
    10801 ctcttgtatc acttctttca gacgatcttt cctggaggat ttttcggggt agatgtcttt
    10861 ttcacatttt caggtttcct gattacagct ctactcattg aagaattttc taagaacaat
    10921 gagattgatt tgataggatt ttttagaaga cgcttttatc ggattgtgcc acctgtggtt
    10981 ttgatggtct tggtgaccat gccttttact ttcttggttc gccaagacta tgttgctgga
    11041 attggtggcc agattgcggg cgtcttaggc tttatgacca acttctatga actcttaaca
    11101 ggtgggagtt atgaatctca gttcattcct catttgtttg ttcataattg gagtttggca
    11161 gttgaggttc actactatat tctttgggga ttggcagttt ggttcttatc caaacaagct
    11221 aaatcaaatg gtcagttgaa ggggatgatc tttctcttat ctgctactgc cttcttgatc
    11281 agtttcttct ccatgtttat tggtagtttt ctagtgacct cttattcctc tgtttatttc
    11341 tccagtttaa ctcatgtcta tccattcttt ttgggaagta tgttagcaac tattgtaggc
    11401 gttcgtcaga cgacttccct cgtcaagcag ttggataaaa tctgggattt acgaaagact
    11461 ttggtagttt ttggaggagg ctttggtttc ctagttcttt tgactttctt tgtcaaattc
    11521 acttatcttt ttgcctatct tatcggcttc ttgcttgcca gtcttgcagc tcttgccatg
    11581 attctggcgg cgcgtgtctt acatgaaaag acacatcata tacaggagcc gaagattatc
    11641 agctttttag cggatactag ctatgcggtt tatcttttcc attggccttt ctatatcatt
    11701 ttctcacagt tgacatcaaa tcttcttgct gtattactga ctctgatttg ttcttatggc
    11761 tttgccagtc tgtcatttta tgtattggaa ccttggattg caggcaagaa cacacctatt
    11821 gtccaaaccc ttcgtcccct gccttatatt cacgcaattc ttgcagcagg tacaggaatc
    11881 ttgaccttca ttgtctgcat ggtgaccttg ttggcaccac aagtgggagc gtttgagaca
    11941 gacttgactg tcaatggctt gaagcaagct gcaacaaata ttggccagac caaggtgatg
    12001 gcagaacggg cagatgcaaa cagtttggga attgctgatg gcactatgtt aattggtgac
    12061 tcagtggctt taagggcaaa tacagcacta cagacagctc ttcctggagc acagattaac
    12121 gcgcaggtca gcgtaacaac caagatcgca aatgaaatca tgctaaataa tagccagaat
    12181 aaatttttac ctaagacggt ggtcattgcg actggggtaa ataatcctga gaactacaag
    12241 gatgactggg acagtatcgt gaaaaatctt cctaagggac accatatgat tttggtgact
    12301 ccttatgagg gagataagac aaaagagacc tatgccatcg ttgagaaggc tgctgcctat
    12361 atgagagaat tggcagagaa gacaccttac attacgatag cagattggaa tcaagttgcg
    12421 aaagagcatc cagaaatttg ggctggaaca gatcaggttc atttcgggag tgagagtagc
    12481 actatcgaag caggagcaaa attgtatgca gatacgattg ccacagcttt gcagacagct
    12541 caagacaagc cggttaaatc aaaataactt gtattaaaaa agagaagagt tggagaaatc
    12601 cagctctttt aaaatatctc caaaaaatag gtatatacca tttacaaata aaaaagaaag
    12661 gtttataatg taattgatat aacaaattgt agaatcaatc ttttaaggag gttaacatta
    12721 tgcctaacta tattaaagcg gatcagtttt tctacccaca cggagttcgt cgaggtggtt
    12781 acttggaact tgtggacggc aagtttggaa aacatgtaga gcagattcct gaaggggctg
    12841 aggtgattga ctatacaggt tatagcattg ccccaggtct tgtggatact catattcatg
    12901 gatatgcagg tgtagatgtg atggacaaca acattgaagg tacattgcat actatgagtg
    12961 aaggacttct tagtaccggt gttaccagtt tcttacccac aactttaaca gccacttatg
    13021 agcaattgct tgcagtcact gaaaatcttg gaaaccatta taaagaagca acaggtgcta
    13081 agattcgtgg gatttattat gaaggtccat atttcacaga aacttttaag ggggcacaaa
    13141 atccaactta tatgagagac ccgggtgttg aggagtttca ttcttggcaa aaagcggcaa
    13201 atggcttgct taataaaatt gcccttgcac cagaacgtga tggggtggaa gactttgttc
    13261 gtacagttac gggcgaaggt gtgacggttg ctcttggaca ttcaaacgcg acttttgatg
    13321 aagccaaaaa agcagtcgat gctggagcga gtgtttgggt gcatgcctac aatggaatgc
    13381 gtgggttgac tcaccgtgaa ttgggtatgg ttggagccat gtaccaattg ccacatacct
    13441 atgcagagtt gatctgtgat ggtcaccacg tagatccaaa ggcttgcgaa attcttatca
    13501 aacaaaaagg aacagaaaac atcgctctta tcacagactg tatgacagct gggggattgg
    13561 aagacggaga ttatatgttg ggagaattcc cagttgtcgt tgcaaatgga actgcacgcc
    13621 tcaaatcgac aggtaacttg gcaggttcta tcctcaaact caaagatggt ttgaagaatg
    13681 tggtcgaatg gggaattgcg aatccgcatg aagcagtcat gatggccagc ttcaacccag
    13741 ctaaatccgt tcacatcgat gacgtctgtg gccaaatccg tgaaggctac gacgctgact
    13801 tcatcgtatt agataaagat ttggaattgg tagcaaccta cctagatggc gtgaaacgtt
    13861 atcaagcata agagagaaag cagaagttag agactaactt ctgctttttt atgcagggta
    13921 ctttactggt aaataaaaag ttaaaaaaat cacaaaaaaa gcttgaagaa acaaagaaaa
    13981 aggcttacaa ttgaactata aatagtacaa ataaaaaaac ggaggagtgc tttatgaaag
    14041 cttatactta tgttaaacca ggacttgctt cttttgttga tgtagacaaa ccagttattc
    14101 gcaagccaac agacgctatt gtgcgtattg taaaaaccac tatttgtgga acagacctcc
    14161 atattatcaa aggggatgtt cctacttgcc aaagtggtac cattcttggc cacgaaggga
    14221 ttgggattgt tgaagaagtt ggggaaggag tttccaactt caaaaaaggt gacaaggtct
    14281 tgatttcttg cgtctgtgcc tgtggtaaat gctactactg taaaaaagga atttatgccc
    14341 actgtgaaga cgaagggggc tggattttcg gtcacttgat tgatggtatg caggctgaat
    14401 atctacgtgt ccctcatgca gataatactc tttaccatac tccagaagac ttgtcagatg
    14461 aagctttggt tatgctgtca gacattctgc ctactggata tgaaattggt gtcttaaaag
    14521 ggaaagtaga acctggttgc agcgtagcca ttattggttc aggtccagtt ggattggctg
    14581 ctcttttaac agcccaattc tattcaccag ctaaattgat tatggtagac ctagacgata
    14641 accgcttgga aactgcccta tcattcggtg cgactcataa ggttaattct tcagaccctg
    14701 aaaaagccat taaagaaatt tatgatttga cagatggtcg tggtgtggat gtcgctatcg
    14761 aagctgttgg tattcctgca acatttgatt tctgtcaaaa gattatcggt gtagacggaa
    14821 cggttgccaa ctgtggtgtg catggtaaac cagttgaatt cgatttagat aaactttgga
    14881 ttcgcaacat caatgtaaca actggtttgg tatctacaaa tacgactcca caattgttga
    14941 aagcacttga aagtcataag attgaaccag aaaaattggt aactcactat ttcaaactca
    15001 gtgaaattga aaaagcctac gaagtcttca gtaaggcagc agaccaccat gccattaagg
    15061 tcattatcga aaacgatatc tcagaagcct aagtagtaaa aatatttttg tacataagta
    15121 aatagaaatt cagtcatcca tcagatggct ggatttttta tcaaaaaatt cagaaatgag
    15181 catatttctt tccttgtctg gcggaattgg ttataatata cggtacaaag gaatgaatga
    15241 atatgtatcg tgttatagaa atgtacggag attttgaacc gtggtggttc ttagaaggtt
    15301 gggaagaaga tattgtagca agtagaaaat ttgatcagta ttatgatgct ctcaaatact
    15361 acaaaacttg ctggtttaga ttggaacaag aatcccctct ttataaaagt agaagcgatt
    15421 tgatgaccat tttttgggac ccggaagacc aacgctggtg tgatgaatgt gatgagtatt
    15481 tacaacaata ccattctttg gctcttttgc aggatgagca ggttatccca gacgaaaaac
    15541 tacgctcagg ctatgaaaaa caaaccagtc aggaaaggaa tcgttcttgc cgtatgaaat
    15601 taaaatagag aaaagtaact tttttggagt tgcttttttt atttttctaa ctctttgcga
    15661 atagtatagg tgaggaggta agtatggttc aagaaattgc acaagaaatc attcgttcag
    15721 ctcgggaaaa agggacgcag gatatttatt ttgtccctaa gttagacgcc tatgagcttc
    15781 atatgagggt aggagacgag cgctgtaaaa ttggtagcta tgattttgaa aagtttgcag
    15841 ccgttatcag tcactttaag tttgtggcgg gtatgaatgt gggagaaaaa agacgtagtc
    15901 aactgggttc ctgtgattat gcctatgacc agaagatggc gtctctacgt ttatctactg
    15961 taggcgatta tcgggggcat gagagtttgg ttatccgttt gttgcacgat gaggaacagg
    16021 acttgcattt ttggtttcag gatattgaag aattaggcaa gcagtacagg caacggggac
    16081 tctatctttt tgctggtccg gttgggagtg gtaagacgac cttgatgcat gaattgtcca
    16141 agtcactctt taaaggacag caagttatgt ccatcgaaga tcctgtcgaa atcaagcagg
    16201 acgacatgct tcagttgcag ttgaacgaag caatcggcct aacctatgga aatctaatca
    16261 aactttcctt gcgtcatcga ccagatctct tgattatcgg agaaattcgt gacagcgaga
    16321 cggcgcgtgc agtggtcaga gctagtttga caggtgcgac agtcttttca accattcacg
    16381 ccaagagtat ccgaggtgtt tatgagcgtc tgctggagtt gggtgtgagt gaagaagaat
    16441 tggcagttgt tctgcaagga gtctgctacc agagattaat cgggggagga ggaatcgttg
    16501 actttgcaag cagagattat caagaacacc aagcagccaa gtggaatgag caaattgacc
    16561 agcttcttaa agatggacat atcacaagtc ttcaggctga gacggaaaaa attagctaca
    16621 gctaagcaaa aaaatatcat caccctattt aacaatctct tttctagcgg ttttcatctg
    16681 gtggagacta tctccttttt agataggagt gctttgttgg acaagcagtg tgtgacccag
    16741 atgcgtgtgg gcttgtctca ggggaaatca ttctcagaaa tgatgaaaag tttgggatgt
    16801 tcaagtgcta ttgtcactca gttatcccta gctgaagtcc atggtaatct ccacctgagt
    16861 ttgggaaaga tagaagagta tctagacaat ctggccaagg tcaagaaaaa attaattgaa
    16921 gtagcgacct atcctttgat tttgctgttt tttcttctct taattatgct ggggctacgg
    16981 aattacctgc tcccacaact ggatagtagc aatattgcca cccgaattat cggtaatctg
    17041 ccacaaattt ttctaggcat ggtagggctt gtttccgtgc ttgccctttt agcactaact
    17101 ttttataaaa gaagttctaa gatgagtgtc ttttctatct tagcacgcct tccctttatt
    17161 ggaatctttg tgcagaccta cttgacagcc tattatgcac gtgaatgggg gaatatgatt
    17221 tcacagggaa tggagctgac gcagattttt caaatgatgc aggaacaagg ttcccagctc
    17281 tttaaagaaa tcggtcaaga tctggctcaa accctgaaaa atggccgtga attttctcag
    17341 acgataggaa cctatccttt ctttaggaag gaattgagtc tcatcataga gtatggggaa
    17401 gttaagtcca agctgggtag tgagttggaa atctatgctg aaaaaacttg ggaagccttt
    17461 tttacccgag tcaaccgcac catgaatttg gtgcagccac tggtttttat ttttgtggca
    17521 ctgattatcg ttttacttta tgcggcaatg ctcatgccca tgtatcaaaa tatggaggta
    17581 aatttttaaa atgaaaaaaa tgatgacatt cttgaaaaaa gctaaggtta aagcttttac
    17641 attggtggaa atgttggtgg tcttgctgat tatcagcgtg cttttcttgc tctttgtacc
    17701 taatctgacc aagcaaaaag aagcagtcaa tgacaaagga aaagcagctg ttgttaaggt
    17761 ggtggaaagc caggcagaac tttatagctt ggaaaagaat gaagatgcta gcctaagaaa
    17821 gttacaagac gatggacgca tcacggaaga acaggctaaa gcctataaag aataccatga
    17881 taaacaaaat actagtcaaa tcgttaaaga ttaaggcctt taccatgctg gaaagtctct
    17941 tggttttggg acttgtgagt atccttgcct tgggcttgtc cggctctgtc cagtccactt
    18001 ttgcagcggt agaggaacag attttcttta tggagtttga agaactctat cgggaaaccc
    18061 aaaaacgcag tgtagctagt caacaaaaga ctagtctgaa cttggatggg cagatgatta
    18121 gcaatggcag tcaaaagttg ccagtcccta aaggaattca ggccccatca ggccaaagta
    18181 ttacatttga ccgtgctggg ggcaattcgt ccctggctaa ggttgaattt cagaccagta
    18241 aaggagcgat tcgctatcaa ttatatctag gaaatggaaa aattaaacgc attaaggaaa
    18301 caaaaaatta gggcagtgat tttactggaa gcagtagtcg ctctagctat ctttgccagc
    18361 attgcgaccc tccttttggg acaaattcaa aaaaataggc aagaggaagc aaaaatcttg
    18421 caaaaggaag aagtcttgag ggtagctaag atggccttgc agacggggca aaatcaggta
    18481 agcatcaacg gagttgagat tcaggtattt tctagtgaaa aaggattgga ggtctaccat
    18541 ggttcagaac agttgttggc aatcaaagag ccataaggtc aaggctttta ccttgttaga
    18601 atccctgctt gccctcattg tcatcagtgg gggattactc ctttttcaag ctatgagtca
    18661 gctcctcatt tcagaagttc gctaccagca acaaagcgag caaaaggagt ggctcttgtt
    18721 tgtggaccaa cttgaggtag aattagaccg ttcgcagttc gaaaaagtag aaggcaatcg
    18781 cctatacatg aagcaagatg gcaaggacat cgccatcggt aagtcaaagt cagacgattt
    18841 tcgtaaaacc gatgctagtg gacgggggta tcagcctatg gtttatggcc tcaaatcagc
    18901 tcagattaca gaggacaatc aactggttca ttttcgtttc cagtttcaaa aaggcttaga
    18961 aagggagttc atctatcgtg tggaaaaaga agaaagttaa ggcaggtgtt ctcctctatg
    19021 cagtcaccat ggcagctatc tttagtcttt tgttgcaatt ttacttgaac cgacaagtcg
    19081 cccactatca agactatgct ttgaataaag aaaaattggt tgcttttgct atggctaaac
    19141 gaaccaaaga taaggttgag caagaaagtg gggaacaggt ttttaatcta ggtcaggtaa
    19201 gctatcaaaa caagaaaact ggcttagtga cgagggttcg tacggataag agtcaatatg
    19261 agtttctgtt ttcttcagtc aaaatcaaag aagagaaaac ggataaaaag gaagaggtag
    19321 tgactgattc aagcgaaaaa gcggagaaaa aaaatcagaa gagaagcctg aaaagaaaga
    19381 gaattcatag tcaattcaac tataatgcgt tgaatccaga atagtccact gtagtttcta
    19441 gaaaattgct ggaaatggat gttaatctcc aattcatttg tttatatctt atttcagttt
    19501 actatacttt gtgctaaact aaagatatga aacatgattt taaccacaaa gcagaaactt
    19561 tcgattcccc taaaaatatc ttcctcgcaa acttggtatg tcaagcagcc gagaaacaga
    19621 ttgatcttct atcagacaaa gaaattttag atttcggtgg tggcgggtct attagccttg
    19681 cccctaaccc ctagccaagc aggctaagtc agtcactctt gtagacattt ctgagaaaat
    19741 gttggagcaa gctcgtttga aagtggagca gcaagcaatc aagaatatcc agtttttgga
    19801 gcaagattta ccgaaaaatc ccttggagaa agagtttgat tgccttgctg ttagtcgggt
    19861 tcttcatcat atgcctgatt tggatgcggc tctctcactg tttcatcaac atttgaagga
    19921 agatgggaaa ctcatcattg ctgattttac caagacagaa gctaatcatc atggatttga
    19981 tttagctgaa ctggaaaaca agctaattga gcatggtttt tcatctgtgc atagtcagat
    20041 tctctatagc gctgaagacc tgtttcaagg aaatcactca gaattctttt taatagtagc
    20101 ccaaaaatca ctcgcctagt cagggagtga tttttctata aggatggaaa aaagaaggga
    20161 aatttgataa gataggaata tggattttga aaaaattgaa caagcttata cctatttact
    20221 agagaatgtc caagtcatcc aaagtgattt ggcgaccaac ttttatgacg ccttggtgga
    20281 gcaaaacagc atctatctgg atggtgaaac tgagctaaac caggtcaaag acaacaatca
    20341 ggcccttaag cgtttagcac tacgcaaaga agaatggctc aagacctacc agtttctctt
    20401 gatgaaggct gggcaaacag aacccttgca ggccaatcac cagtttacac cggatgctat
    20461 tgctttgctt ttggtgttta ttgtggaaga gttgtttaaa gaggaggaaa ttactatcct
    20521 cgaaatgggt tctgggatgg gaattctagg cgctactttc ttgacctcgc ttgataaaaa
    20581 ggtggattac ttgggaatgg aagtggatga tttactgatt gatctggcag ctagcatggc
    20641 agatgtaatt ggtttgcagg ctggctttgt ccaaggagat gccgttcgtc cacaaatgct
    20701 caaagaaagc gatgtggtca tcagtgactt gcctgttggc tattatcctg atgatgccgt
    20761 tgcgtcgcgc catcaagttg cttctagcca agaacatact tacgcccatc acttgctcat
    20821 ggaacaaggg cttaagtacc tcaagtcaga cggatacgct atttttctag ctccgagtga
    20881 tttgttgacc agtcctcaaa gtgatttgtt aaaagaatgg ctgaaagaag aggcgagtct
    20941 ggttgctatg attagtctgc ctgaaaatct ctttgctaat gctaaacaat ctaagactat
    21001 ttttatccta cagaagaaaa atgaaatagc agtagagcct tttgtttatc cacttgctag
    21061 cttgcaagat gcaagtgttt taatgaaatt taaagaaaat tttcaaaaat ggactcaagg
    21121 tactgaaata taaaatagat tttgttataa tagttgaaaa cgcttaaaaa ggggtatcat
    21181 gttatgacaa aaacaattgc aatcaatgca ggaagttcaa gtttgaaatg gcaattatac
    21241 ttaatgccag aagaaaaagt attggcgaaa ggtttgattg aacgtatcgg tttgaaagat
    21301 tcaatttcaa ctgtaaaatt tgacggccgt tctgaacaac aaattttgga tattgaaaat
    21361 catacacaag ccgttaaaat tttattggat gacttgattc gtttcgatat tatcaaggct
    21421 tatgacgaga ttacaggtgt tggacatcgt gttgttgctg gtggagaata tttcaaagaa
    21481 tcaacagttg ttgagggaga tgttttagaa aaagttgaag agttgagttt gttggctcct
    21541 ctacacaacc cggccaatgc agcaggtgtt cgtgccttca aggaattgtt gccagacatt
    21601 accagtgtag ttgtttttga tacttccttc cacacaagta tgccagagaa agcttatcgc
    21661 taccctctac caacaaaata ttacacagaa aacaaggttc gtaaatacgg tgctcatggt
    21721 acaagtcacc agtttgtagc aggagaagct gcaaaactct tgggacgtcc attagaagac
    21781 ttgaagttaa ttacctgtca tattggtaac ggaggctcaa ttacagctgt gaaagccggc
    21841 aaatctgtag acacttctat ggggttcact cctcttggtg gtattatgat gggaacgcgt
    21901 acaggggata ttgatccagc tatcattcct tatttaatgc aatatacaga ggattttaac
    21961 acaccagaag atatcagtcg tgttcttaac cgtgaatcag gtcttttggg agtttctgct
    22021 aattctagcg atatgcgcga tatagaagca gctgtagcag aagggaatca cgaggctagc
    22081 ttggcttatg aaatgtatgt tgaccgtatc caaaaacata tcggtcagta ccttgcagtg
    22141 ctaaatggag cagatgccat tgttttcaca gcaggtgtcg gtgaaaatgc agagaatttc
    22201 cgtcgtgatg taatctcagg gatttcgtgg tttggttgtg atgttgatga tgaaaagaat
    22261 gtctttggcg ttacaggaga catctcaaca gaggcagcta aaatccgtgt cttggttatt
    22321 ccaacagatg aagaattagt cattgcccgt gacgttgaac gcttgaaaaa ataagtgaaa
    22381 ctaaaaaaat attcaataca aggagttggg aaagttattt ttccagcttc tttttctgat
    22441 gaaattgtcc aaaaccttgc tatgattggc ttttttgaaa aatatggtat aatagtagta
    22501 atttaataga tggagttgag ttttgaagaa aaactttcgt gtaaaaagag agaaagattt
    22561 taaggcgatt ttcaaggagg ggacaagttt tgctaatcgc aaatttgtgg tctaccaatt
    22621 agaaaaccag aaaaaccatt ttcgagtagg tctatcagtt agcaaaaaac tggggaatgc
    22681 cgtcactaga aatcaaatta agcgacggat tcggcatatt atccagaatg caaaagggag
    22741 tctggtagaa gatgtcgact ttgttgtcat tgctcgaaaa ggagtcgaaa ccttgggata
    22801 cgcagagatg gagaaaaatc tactccatgt attaaaatta tcaaagattt accgggaagg
    22861 aaatgggagt gaaaaagaaa ctaaagttga ctagtttgct aggactgtct ctgttaatca
    22921 tgacagcctg tgcgactaat ggggtaacta gcgatattac agccgaatcg gctgattttt
    22981 ggagtaaatt ggtttacttc tttgcggaaa tcattcgctt tttatcgttt gatattagta
    23041 tcggagtggg gattattctc tttacggtct tgattcgtac agtcctcttg ccagtctttc
    23101 aggtgcaaat ggtggcttct aggaaaatgc aggaagctca gccacgcatt aaggcgcttc
    23161 gagaacaata tccaggtcga gatatggaaa gcagaaccaa actagagcag gaaatgcgta
    23221 aagtatttaa agaaatgggt gtcagacagt cagactctct ttggccgatt ttgattcaga
    23281 tgccggttat tttggccctg ttccaagccc tatcaagagt tgacttttta aagacaggtc
    23341 atttcttatg gattaacctt ggtagtgtgg atacaaccct tgttcttccg attttagcag
    23401 cagtattcac ctttttaagt acttggttgt ccaacaaagc tttgtctgag cgaaatggcg
    23461 ctacgactgc gatgatgtat gggattccag tcttgatttt tatctttgca gtttatgcgc
    23521 caggtggagt cgccctatac tggacagtgt ctaatgctta tcaagtcttg caaacctatt
    23581 tcttgaataa tccattcaag attatcgcag agcgcgaggc cgtagtacag gcacaaaaag
    23641 atttggaaaa tagaaaaaga aaagccaaga aaaaggctca gaaaacgaaa taaataagga
    23701 ggaatctggt aatggtagta tttacaggtt caactgttga agaagcaatc cagaaaggat
    23761 tgaaagaatt agatattcca agaatgaagg ctcatatcaa agtcatttct agggagaaaa
    23821 aaggctttct tggtctattt ggtaaaaaac cagcccaagt ggatattgaa gcgattagtg
    23881 aaacgactgt tgtcaaagca aatcaacagg tagtaaaagg cgttccgaaa aaaatcaatg
    23941 atttgaacga gcctgtgaag actgttagtg aagaaaccgt tgaccttggt catgtggttg
    24001 atgctattaa aaaaatagag gaagaaggtc aaggtatttc tgatgaagtc aaggctgaaa
    24061 tcttaaaaca tgaaagacat gccagcacta tcttagaaga aactggtcac attgagattt
    24121 taaatgaact tcaaatcgag gaagcgatga gggaagaagc aggcgctgat gaccttgaaa
    24181 ctgagcaaga tcaaactgaa aatcaagact tgaaagagat gggcttgaag gtcgagcaaa
    24241 gttatgatat tgcccaggtg gctacggatg tgactgctta tgttcaaacg attattgatg
    24301 acatggatgt tgaggctaca ctttcaaatg attataaccg tcgtagcatc aatttgcaaa
    24361 ttgatactaa cgaaccaggt cgtattatcg gctaccatgg taaagtcttg aaggccttgc
    24421 aactgttggc tcaaaattat ctttacaact gctattcaag aaccttctat atcactatta
    24481 atgtcaatga ttatgttgaa caccgtgcag aagtcttgca gacctatgcg caaaaattgg
    24541 cgattcgtgt tttagaagaa ggacgtagtc atcaaacaga tccaatgtcg aatagtgaac
    24601 gcaagattat ccaccgtatt atttcacgta tggatggcgt gaccagttac tctgaaggtg
    24661 atgagccaaa tcgctatgtc gttgtagata cagaataagt aaaatcaggg ttgacctgat
    24721 tttttgctag ctagaggagg ttaaactgat gttgaataag ataagagact atctagactt
    24781 ttctggtttg cagtaccgta gtcctgataa agcgggagca gagcgagaga agatgctggc
    24841 gttccgccac aaaggacaag aggcccgaaa ggcttttaca gaactggcca aagcctttca
    24901 agcaagccat ccagaatggc aactccaaca gactagtcag tggatgaatc aggcccagcg
    24961 tttgagacca catttttggg tttatctaca gagagacgga caagtgacag aacctatgat
    25021 ggccttacgt ttgtatggga catctactga ctttggaatt tctttggaag tcagtttcat
    25081 cgaacgtaag aaggatgagc aaacactggg caagcaggcc aagattttag acattccaac
    25141 cgttaaaggg atttattatc taacctactc taatggtcaa agtcaacggt gggaggcgaa
    25201 tgaagaaaag cgtcgtactt tacgcgagaa ggtgagaagt caagaagttc gaaaagtttt
    25261 agtgaaggta gatgttccta tgacagaaaa ttcgtctgaa gaagaaatcg tagaaggctt
    25321 attgaagtct tattctaaaa ttcttcccta ttatctagct acgagaaaat aagataattt
    25381 gtaaaacatc ataaatcata cagtccaaga gtgaacagtc cgctgtgtaa ttcttggtct
    25441 ttttgtttgc gctttcgcat tatataataa acttacaaaa acaattcaaa aggagaacaa
    25501 ttatggaagt cgtttcaagt gttctaaatt ggttttctag caatattttg cagaatcccg
    25561 catttttcgt aggtttattg gtgttgatag gatatgcact tttgaaaaaa cctgcccatg
    25621 acgttttttc agggtttgtt aaagcaacag tagggtatat gttgcttaac gtgggtgctg
    25681 gtggtttggt tacaaccttt cgtccaatct tagcagctct taactacaaa ttccaaattg
    25741 gtgcagcggt tatcgaccct tactttggac ttgctgcagc aaacaacaaa attgcagcag
    25801 agtttccaga ttttgttgga actgcaacta cagctctatt gattggtttc ggaataaata
    25861 tcttgctcgt agctcttcga aagattacga aggtaagaac cctctttatt actggtcaca
    25921 tcatggtaca acaagctgca acagtatctc ttatggttct attcttagta ccacaattgc
    25981 gcaatgctta cggtacagca gcgattggta tcatctgtgg actttactgg gcagttagtt
    26041 caaatatgac tgttgaggca actcaacgct tgactggtgg tggcggattt gcgattggtc
    26101 accaacagca atttgcaatc tggtttgtag ataaagtagc aggacgcttt ggtaagaaag
    26161 aagaaagttt agacaatctt aaattaccta agttcctctc aatcttccac gatacagttg
    26221 ttgcatctgc taccttgatg ctcgtattct tcggggccat tcttttaatc ttgggtccag
    26281 acattatgtc taataaagaa gtcatcactt caggaactct attcaatcct gctaaacaag
    26341 atttctttat gtacattatc caaacagcct ttaccttctc agtttacttg ttcgttttga
    26401 tgcaaggtgt ccgaatgttc gtatctgagt taacaaacgc tttccaaggt atttcaaaca
    26461 aattgttgcc aggttcattc ccagcggttg acgttgcagc ttcttatgga tttggttctc
    26521 caaatgctgt cttgtcagga tttacctttg gtttgattgg tcaattgatt acaattgtct
    26581 tgctcatcgt ctttaaaaat ccgattctta ttattacagg atttgtacca gtgttctttg
    26641 acaatgcagc cattgcggtc tacgctgata aacgcggcgg atggaaagcg gctgttatcc
    26701 tttcctttat atcaggtgtc cttcaagttg ctctaggagc tctttgtgtg gcccttctcg
    26761 atttggcatc ttatggtggc taccatggaa atatcgactt tgaattccca tggcttggat
    26821 ttggatatat cttcaaatac cttggtattg ttggttatgt acttgtgtgt ctcttcttgc
    26881 ttgttattcc tcaacttcaa tttgccaaag caaaagataa agagaaatat tacaacggtg
    26941 aagttcaaga agaagcttag tatctagaaa aggagaaata aaatggttaa agtattagca
    27001 gcgtgcggaa atggaatggg ttcatcaatg gttatcaaga tgaaggttga aaatgctctc
    27061 cgtaagctta atcaaacaga ttttacagtc aattcatgca gtgtcggtga agctaaaggt
    27121 ttagcagtag gatatgacat cgtaatcgct tctcttcatt tgattcaaga attggaaggg
    27181 cgaactaatg ggaagttaat tggtcttgat aacttgatgg atgataaaga aatcaccgaa
    27241 aaactcagtc aagcactata gtaaaaggtt ggaggggact ggacagaaac tgagagttat
    27301 cgtttctgtc cttctccctc tttaaataaa ggaggcagat atgaatttaa aacaagcttt
    27361 aattgacaac gactcgatcc gactaggttt agaggctaac gattggaaag aagcagtcaa
    27421 ggtagcagta gatcccttga ttgaaagtgg ggcaattttg ccagagtatt acgatgctat
    27481 cattgaatcg actgaagagt atgggcctta ctatatcttg atgccaggta tggctatgcc
    27541 ccacgctaga cctgaagctg gtgtgcaaag tgatgccttt tcattgatta ccttacaaaa
    27601 tcctgttgta ttttcagatg ggaaagaggt atctgttttg ttggcactag cagcaacaag
    27661 ttcaaaaatt cacacaagtg tggccattcc acaaattatt gccctgtttg aattagaaga
    27721 ttctattgca cgtttacagg cttgccagac taaagaagat gtcttggcta tgattgaaga
    27781 atctaaggat agcccttatc tcgaaggatt ggatttggaa agttagaaag aggaataaag
    27841 aaatgacaaa aagaatacct aatttacaag ttgcattaga ccattcagac ttgcaaggag
    27901 cgattaaagc agctgtttct gttggtcagg aagtagatat tatcgaagct ggaactgttt
    27961 gcttgcttca agttggaagt gaactggctg aagtcttgcg tagccttttc ccagataaga
    28021 ttattgtggc agacacaaaa tgtgctgatg ctggtggaac agttgctaaa aataatgcgg
    28081 ttcgtggagc agactggatg acttgtatct gttgtgcaac catccctact atggaagcag
    28141 ctctaaaggc tatcaagact gaacgaggag aacgaggcga aatccagatc gagctttatg
    28201 gcgattggac ttttgaacaa gctcagcttt ggctagatgc aggtatctca caagctattt
    28261 atcaccaatc tcgtgatgct cttcttgctg gtgaaacttg gggtgaaaaa gaccttaata
    28321 aggttaaaaa actcattgac atgggcttcc gtgtatctgt aacaggtggt ctagatgtag
    28381 atactctcaa actctttgaa ggtgttgatg tctttacctt tatcgcaggt cgtagaatta
    28441 cagaggctgc ggatccagca ggagcagcgc gtgccttcaa ggatgaaatc aaacgaattt
    28501 gggggtaaat catggtacgt ccaattggaa tttatgaaaa ggcaacccca acacacttta
    28561 cttggctaga acgtttaaat tttgccaagg agttaggctt tgattttgtc gagatgtcta
    28621 ttgacgaacg tgacgagcgt ttagcaagac ttgactggag taaggaagaa cgcttggaag
    28681 ttgtcaaagc aatctatgaa actggtgttc gtattccttc tatctgtttt tcaggccatc
    28741 gtcgctaccc attgggttca aaagatccag ttctagagga aaaatctcta gaactcatga
    28801 aaaaatgtat cgaattagct caagacttgg gagttcgtac gattcaatta gctggttacg
    28861 atgtttacta tgaggaaaag tcaccccaga cacgccaacg ttttatcaaa aatttgagaa
    28921 aagcctgtga ctgggctgaa gaagctcagg tggtacttgc tattgaaatt atggatgatc
    28981 ctttcatcaa tagcatcgaa aaatatttgg ctatagaaaa agagattgac tctcccttcc
    29041 tctttgtata tccagatatt ggtaatgtgt ctgcatggca taatgatatc tatagtgagt
    29101 tttatcttgg tcatcatgcc atcgcagctc tccatctcaa ggatacttat gcagtgacag
    29161 aaagttcaaa gggccagttc cgagatgtac ctttcgggca aggttgtgtc aaatgggaag
    29221 aagctttcga tattttaaag gaaaccaatt ataatggacc tttcctaatc gaaatgtggt
    29281 ctgaaaattg tgaaacagta gaagaaacac gcgcagccgt tcaagaggcg caagcttttc
    29341 tctatccact cattaagaaa gcaggtttga tgtaagatga atcaagtaat caatgctatg
    29401 cgtaaacgag tctgtgatgc caatcaatca ttgccaaaac atggacttgt caaatttacc
    29461 tgggggaatg tatctgaagt taatcgcgaa ctcggtgtca ttgttatcaa accatcaggc
    29521 gtggattatg acgaattgac acctgaaaac atggtagtga ctgatctaga tggtaagatc
    29581 ctagaagggg atttaagacc atcttccgac ctcccaactc atgtgcaatt atataaggct
    29641 tggtcagaaa ttggtagtgt ggttcacacc cattcgacag aagctgttgc ttgggctcag
    29701 gcaggtcgtg atattccttt ctacggaaca acccatgcag attatttcta cggttcaatc
    29761 ccttgcgccc gtagtttgac caaggacgaa gtagaagtgg cctatgaaaa agatactggc
    29821 ctggttatcg tagaagagtt tgaacatcgc ggacttaacc cggttgaagt accaggaatt
    29881 gttgtacgca atcacggtcc attcacctgg ggcaaaaatc cagagaatgc tgtttatcac
    29941 tctgtcgtac tagaggaagt atcaaagatg aatcgcttta cagaacaaat caatccaaga
    30001 gttggacctg ctccccagta catactagaa aaacactacc aacgtaaaca tggaccaaat
    30061 gcttattatg gtcaaaagta agaacgatga aggaggagaa aaagataaat ttagctcctc
    30121 tttttacatt tgatttttat tgagagtaaa gttggaattg aagtaatttt aaaagatttt
    30181 ttagaaatag cgcttgatat atatatggta aaataaaaag aattgctgtg atatcaatag
    30241 atttggggga ttttttaata tggtactgga taaggcaagt tgtgatttgc ttcaatattt
    30301 gatggatcaa gaaacgtcca aaacgattat ggcgatttcg aaagatttga aagagtcaag
    30361 aaggaaaatt tattatcaca ttgacaaaat caatgctgct ctgggtgacg aggcgcttca
    30421 catcattagt attccacgaa ttggtattca cttaacggaa gagcagagag atgcttgttg
    30481 taaactatta tcggaagtag attcgtacga ttatatcatg agtgcgcatg aacgtatgat
    30541 gataatgtta ctatggatag gtatttctaa agaacgtatt acgattgaaa aattgataga
    30601 gttaacagag gtatctagga atactgttct caatgatttg aatagtattc gttatcaact
    30661 aactttggaa caatatcagg tgatcttgca agtgagcaag tcacagggat accaccttca
    30721 tgcccaccct cttaataaaa ttcagtatct tcaatcgctt ctatatcata tttttatgga
    30781 agaaaatgcc acttttgtat ctattttaga agataagatg aaagagaggt tagatgatga
    30841 gtgtttgctt tctgttgaaa tgaaccaatt ttttaaggaa caggttcctt tagttgaaca
    30901 agatttaggg aagaaaataa accatcatga aataactttt atgttgcagg ttctacctta
    30961 tttgctgtta agctgtcata atgttgaaca gtatcaagaa agacatcagg atatagagaa
    31021 agaattttct ttgataagaa aaagaataga gtatcaggtg tctaagaaat taggagaacg
    31081 gttgtttcaa aagtttgaaa tttctttgtc aggacttgaa gtttctcttg tagctgttct
    31141 cctcctctcc tatcgtaaag atttggatat tcatgcagaa agtgatgatt ttcggcaatt
    31201 aaaacttgct ttagaagaat ttatctggta ttttgaatca caaatccgaa tggagattga
    31261 gaacaaggat gatttgttac gaaatttgat gatccactgt aaatccttgt tatttagaaa
    31321 gacttacggt attttttcta aaaatcctct aacaaaacaa attcgatcca agtatggaga
    31381 attattttta gtcactagaa aatctgcgga aattttagaa ggagcatggt ttattcggct
    31441 aacagacgat gatattgcct atttgacgat tcatattgga ggatttttaa agtatacacc
    31501 atcgtctcaa aaaaatatga aaaaagttta tctcgtttgt gatgaaggtg ttgcggtttc
    31561 gagacttttg ctgaaacaat gcaaacttta ttttccaaat gagcaaattg acactgtatt
    31621 tacaacagaa caatttaaga gtgtggaaga tattgcacaa gttgatgtag tgattactac
    31681 taatgatgat ttggatagca gatttccgat tttaagggtt aatcctatcc ttgaagcaga
    31741 agatattttg aaaatgctag actatcttaa acacaatata tttcgtaata agagcaaaag
    31801 tttcagtgaa aatctttcta gtcttatttc gtcttatatt gtagacagca agttggctag
    31861 taagttctaa gaagaggttc aaacacttat aaatcaagaa atagtagttc aagctttttt
    31921 ggaagatatt tgaaggacag tccaatgatg aacacaaacc tgtgtttttc ttggtctttt
    31981 ttagtgtttt gaagggtggt atactaatct caaagataac aattatatcc aaaggaggca
    32041 acatatgcca aacgtcaaag aaattacaag agagtcatgg attttagcca ctttcccaga
    32101 gtggggaaca tggttgaacg aagaaatcga agaagaagtc gtacctgaag gcaactttgc
    32161 catgtggtgg ctaggcaact gtggtacttg gattaagaca ccagctggtg ctaacgttgt
    32221 catggacctt tggtcaaacc gtggaaaatc aaccaaaaaa gtgaaagata tggttcgtgg
    32281 gcaccaaatg gcaaatatgg caggtgttcg taaattgcaa ccaaacttgc gtgttcagcc
    32341 aatggttatc gatccatttg ctatcaacga actagactat tacttagttt cacacttcca
    32401 cagtgatcat atcgacccat acacagctgc agcaattctc aacaatccta agttagagca
    32461 tgttaagttt atcggtcctt accactgtgg acgaatctgg gaaggatggg gggttccaaa
    32521 agaacgtatc atcgttgtta aaccaggtga cactatcgaa ttaaaagata tgaagattca
    32581 tgcagtagaa tcatttgacc gtacttgctt ggtaactctc ccagtgaacg gtgctgatga
    32641 gacaggcggt gaacttgctg gcttggctgt tacagatgaa gaaatggctc aaaaggctgt
    32701 taactatatc tttgaaacac caggtggaac catctatcat ggtgcagatt ctcacttctc
    32761 aaactatttt gcaaaacatg gtaaagactt taaaattgat gttgctttga ataactatgg
    32821 tgaaaatccg gtaggtatcc aagacaaaat gacatctatc gaccttcttc gtatggcaga
    32881 aaatctgcgt accaaagtca ttatcccagt tcactatgat atctggtcta acttcatggc
    32941 ttctactaat gagattctag aactttggaa aatgcgaaaa gatcgcttgc aatacgattt
    33001 ccatccattt atctgggaag ttggcggtaa gtacacttat cctcaagatc aacacttagt
    33061 agaataccat catccacgtg gttttgatga ttgttttgaa caagactcta acattcaatt
    33121 taaagctttg ctataatata aaaatattct ttggaggtta tccgtatgtt gcatgatacg
    33181 gataattttc atataatagt aaaatagaat gtgtgattca ataatcacct caaatagaaa
    33241 ggaaattcta tgtcaaatct atctgttaat gcaattcgtt ttctaggtat tgacgccatt
    33301 aataaagcca actcaggtca tccaggtgtg gttatgggag cggctccgat ggcttacagc
    33361 ctctttacaa aacaacttca tatcaatcca gctcaaccaa actggattaa ccgcgaccgc
    33421 tttattcttt cagcaggtca tggttcaatg ctcctttatg ctcttcttca cctttctggt
    33481 tttgaagatg tcagcatgga tgagattaag agtttccgtc aatggggttc aaaaacacca
    33541 ggtcacccag aatttggtca tacggcaggg attgatgcta cgacaggtcc tctagggcaa
    33601 gggatttcaa ctgctactgg ttttgcccaa gcagaacgtt tcttggcagc caaatataac
    33661 cgtgaaggct acaatatctt tgaccactat acttacgtta tctgtggaga cggagacttg
    33721 atggaaggtg tctcaagcga ggcagcttca tacgcaggtt tgcaaaaact tgataagttg
    33781 gttgttcttt atgattcaaa tgatatcaac ttggatggtg agacaaagga ttcctttaca
    33841 gaaagtgttc gtgaccgtta caatgcctac ggttggcata ctgccttggt tgaaaatgga
    33901 acagacttgg aagccatcca tgctgctatc gaaacagcaa aagcttcagg caagccatct
    33961 ttgattgaag tgaagacggt tattggatac ggttctccaa acaaacaagg aactaatgct
    34021 gtacacggcg cccctcttgg agcagatgaa actgcatcaa ctcgtcaagc cctcggttgg
    34081 gactacgaac catttgaaat tccagaacaa gtatatgctg atttcaaaga acatgttgca
    34141 gaccgtggcg catcagctta tcaagcttgg actaaattag ttgcagatta taaagaagct
    34201 catccagaac tggctgcaga agtagaagcc atcatcgacg gacgtgatcc agtcgaagtg
    34261 actccagcag acttcccagc tttagaaaat ggtttttctc aagcaactcg taattcaagt
    34321 caagatgcct tgaatgttgt ggcagctaaa ttaccaacct tcctaggtgg atcagctgac
    34381 cttgctcact caaacatgac ttatatcaag acggatggac ttcaagacga taccaatcgc
    34441 ttgaatcgta acattcagtt tggtgttcgt gaatttgcaa tgggaacaat cttgaacggg
    34501 atggcccttc atggtggact tcgtgtatac ggtggaactt tcttcgtctt ctctgactat
    34561 gtgaaggcag ctgtccgctt gtcagcctta caaggacttc ctgtgactta tgtctttacc
    34621 catgattcaa tcgcagttgg ggaagatggt ccgactcacg aaccggttga gcatttagca
    34681 ggtcttcgtg ctatgccaaa tctaaatgtt ttccgtccag cagatgcgcg tgaaacgcaa
    34741 gcagcttggt accttgcagt gacaagtgag aaaacaccaa ctgcccttgt cttgacacgt
    34801 caaaacttga ctgttgaaga tggaacagac ttcgacaagg ttgctaaagg tgcttatgtt
    34861 gtatatgaaa atgcagccga ctttgatacc atcttgattg cgacaggttc agaggttaat
    34921 cttgctgtct cagctgctaa agaattggct agtcaaggcg aaaaaatccg cgtagtcagc
    34981 atgccatcta cagatgtctt tgataaacaa gatgcagctt acaaggaaga gattcttcca
    35041 aatgcagtcc gccgtcgtgt tgcagtcgaa atgggtgcaa gtcaaaactg gtacaaatat
    35101 gttggtctcg atggtgccgt tctaggtatt gataccttcg gagcctctgc cccagcacca
    35161 aaagtattgg cagaatatgg ctttactgta gaaaatcttg taaaaattgt tcgaaacttg
    35221 aaataatcct aaaaatcagg gcgtaagctc tggtttttct taccagaaaa gtaaggtaca
    35281 atcttgtaaa agtagctaaa atttgatata gtagtcctat gtaaaagaca aaggagaaaa
    35341 caatgaatcc aaatattact tttttaatca tgcttgtagg tatgatggcc ttgatgttct
    35401 ttatgcaacg ttctcaaaag aaacaagctc aaaagcgtat ggaaagctta aataaactac
    35461 aaaaaggcta tgaagtgatt acaatcggtg gactttatgg aacagtcgat gaagtagata
    35521 cggagaaggg aacaatagtt cttgacgtag atggagttta cttaactttt gaactagctg
    35581 ctatcaagac agtattaccg ctgaaagaaa cagcttcact agaaggcgca attgaaaaat
    35641 aagacgggat cacgaactcc cgtttttcta taaaagaaag gaaatgggat gaaaaaatta
    35701 gtctttgtct gtctgggaaa tatttgccgt agccctatgg ccgagtttgt tatgaaatca
    35761 atgacagata actacgaaat ccaaagtcga gcaacttcct cttgggaaca tggcaatccg
    35821 attcataagg ggactcaggg aatttttcaa cagtatgaga ttccttatga caagaacaag
    35881 acatcgcttc agattagtaa ggaagatttt gaagcctttg attatattat cggaatggac
    35941 gcttcaaata tttctgactt acgtcagatg tgtccagtag actgtcaaga taagatttac
    36001 tcattttcat ctgaaagtgt tccagaccct tggtatacag gagattttga agaaacctat
    36061 cgacgtgttc aagagggctg tcaagcttgg ttagaacgtt tagaaaagga gagttaaggt
    36121 ggaaaatctt acgaattttt acgaaaagta tcgtgtttat ctgactcgtc cacgtttaga
    36181 gattttggca gtagttacca ttgttttctg tgctgtactc gtcttttttc taaatattcc
    36241 aggaaaaggt gtcttaaaac tcgataatgg aacgattgtt tatgatggca gtcttgtccg
    36301 cggtaaaatg aatggccaag gtaccattac cttccaaaat ggagaccaat atacaggtgg
    36361 cttcaacaat ggagccttca acggaaaagg tacctttcaa tctaaagaag gctggaccta
    36421 cgaaggtgat tttgtaaatg gtcaggctga aggaaaaggg aaactaacaa cagaacaaga
    36481 agtcgtttat gaaggaactt ttaaacaagg cgtttttcaa caaaaataaa gcctccttat
    36541 caaaggaggt attattagaa ttacaaggta agcgcttacc tgtaaatccc tttctttcca
    36601 aatccctctt ccaagcaagt ttgtgaaata aaaaatattt gaaataaatt tcacaaactt
    36661 caaagataaa acctgataag aaaagaaaat gagaaaagtt tcacaagagt ttaaaaattc
    36721 tttgtgaaat gtttatgaaa ctgtttacaa agttgaaata atgcgttata ataaacttgt
    36781 gaaaaaatta acaaaggata tcgatccttg aaagctatgg aggaaaatat ggctgataaa
    36841 aaaactgtga caccagagga aaagaaactc gttgctgaaa aacacgtaga tgagttggtt
    36901 caaaaagctc tagttgccct tgaagaaatg cgtaaattgg atcaagagca agttgactac
    36961 atcgttgcca aagcatcagt agcagctttg gatgcccacg gagaattggc tttacatgcc
    37021 tttgaagaaa caggacgtgg tgtatttgaa gataaagcaa ctaagaactt gtttgcctgt
    37081 gaacacgtag taaacaacat gcgtcacact aagacagttg gcgttatcga agaagacgat
    37141 gtaacaggat tgactcttat tgctgaacca gttggtgttg tttgtggtat tactccaaca
    37201 acaaacccaa catcaacagc aatcttcaaa tcattgattt cattgaagac acgtaaccca
    37261 atcgtctttg ccttccatcc atcagcacaa gaatcatctg ctcatgcagc tcgtatcgtc
    37321 cgcgatgcag ctatcgcagc tggtgctcct gaaaactgtg tgcaatggat tactcaacca
    37381 tctatggaag caacaagtgc ccttatgaac cacgaaggtg ttgcgacaat ccttgcaaca
    37441 ggtggtaatg ccatggttaa ggcggcttat tcatgtggta aaccagctct tggggtaggt
    37501 gccggaaacg ttccagctta tgttgaaaaa tcagcaaaca ttcgtcaagc agcacacgat
    37561 atcgtcatgt ctaaatcatt tgataacggt atggtctgtg catctgaaca agcagttatc
    37621 attgataaag aaatttacga tgaatttgta gcagagttca aatcttacca cacttacttt
    37681 gtaaacaaaa aagaaaaagc tcttcttgaa gagttctgct tcggcgtcaa agcaaacagc
    37741 aaaaactgtg ctggtgcaaa attgaacgct gacatcgttg gtaaaccagc aacttggatt
    37801 gcagaacaag caggatttac agttccagaa ggaacaaaca ttcttgctgc agaatgtaaa
    37861 gaagttggcg aaaatgagcc attgactcgt gaaaaattgt caccagttat tgcagttttg
    37921 aaatctgaaa gccgtgaaga tggtattact aaggctcgtc aaatggttga atttaacggt
    37981 cttggacact cagcagctat ccacacagct gacgaagaat tgactaaaga atttggtaaa
    38041 gctgttaaag ctattcgtgt tatctgtaac tcaccttcta cttttggtgg tatcggggac
    38101 gtttacaatg ccttcttgcc atcattgaca cttggatgtg gttcttacgg acgcaactca
    38161 gttggggata acgttagtgc cattaacctc ttgaatatca aaaaagtcgg aagacggaga
    38221 aataacatgc aatggatgaa acttccttca aaaacatact ttgaacgtga ttcaattcaa
    38281 taccttcaaa aatgtcgtga cgttgaacgt gtcatgatcg ttactgacca tgccatggta
    38341 gagcttggtt tccttgatcg tatcatcgaa caactggacc ttcgtcgcaa taaggttgtt
    38401 taccaaatct ttgcggatgt agaaccggat ccagatatca caactgtaaa ccgtggtact
    38461 gagattatgc gtgccttcaa accagatacc atcatcgcac tcggtggtgg gtctccaatg
    38521 gatgctgcca aagtaatgtg gctcttctac gagcaaccag aagtggactt ccgtgacctt
    38581 gtccaaaaat tcatggatat ccgtaaacgt gccttcaagt tcccattgct tggtaagaag
    38641 actaaattca tcgcgattcc aactacatct ggtacaggat ctgaagtaac accatttgcc
    38701 gttatctctg ataaagcaaa caaccgtaaa tacccaatcg ctgactactc attgacacca
    38761 actgtggcaa tcgtagatcc tgctttggta ttgacagttc caggatttgt tgctgctgat
    38821 actggtatgg acgtattgac tcacgcaaca gaagcatatg tatcacaaat ggctagtgac
    38881 tacactgatg gtttagcact tcaagccatt aaattggtct ttgaaaatct cgaaagctca
    38941 gttaagaatg cagacttcca ctcacgtgag aaaatgcata acgcttcaac aatcgctggt
    39001 atggcctttg ccaatgcctt cttaggtatt tctcactcaa tggcccataa gattggtgcg
    39061 caattccaca caatccacgg tcgtacaaat gctatcttgc ttccgtacgt tatccgttac
    39121 aacggtacac gtccagctaa gacagcaaca tggcctaagt acaactacta ccgtgcagat
    39181 gaaaaatacc aagatatcgc acgcatgctt ggacttccag cttctactcc agaagaaggg
    39241 gttgaatctt acgcaaaagc tgtctacgaa ctcggtgaac gtattgggat ccaaatgaat
    39301 tttagagacc aaggaattga cgaaaaagaa tggaaagaac attctcgtga attagccttc
    39361 ctggcttatg aagaccaatg ttcaccagct aacccacgtc ttccaatggt agaccatatg
    39421 caagaaatca tcgaagatgc atactatggc tacaaagaaa gaccaggacg ccgtaaataa
    39481 ttgtttatca gtctagaagc aagacaaaaa ctcaatttga gggaaagatc cagtaatttt
    39541 tctatgataa aaggcatcct atcaaggttt ttgaatacct gataggatgc ctttttatga
    39601 tgttgaggcc tttttgccct ttttgaaaaa ctagaataga aacaaaatat atagcagatt
    39661 gaaactagaa tagtacacat ctgcttctaa aacatttata gaaattaatt ttactttcct
    39721 gatagagttg tttacatctt atttcaattc actatagttt aatttaagag tagtatttac
    39781 taaggcccaa ttaaaatcaa agagcaaact agaaaacgag tgccattcag ctcaaaacac
    39841 tgatttgaga ttgcagataa gactagcccc ctcattaaca gatttacgat aaaacgatga
    39901 caaggtgtgt tgctttttga tttctaaaga gtataatgat agatctctat aaaataagtg
    39961 cgaaggaaat gagcttttat agtcctttcg ttttaaaata ctatctcaga tattcttata
    40021 tcgacaagaa gtttttgagt cattccctca tcatacatat taaataaata gtggctcatt
    40081 caatttttca ctagaataat aagctagtat agtaaactga aataagatat aaacaaataa
    40141 attggagctt aacatctatt tccagcaatt ttttagaaac tgcagtggac tattctagat
    40201 tcaacatatt ataaaaacta gagtaaaaga aaaggattgg atcttgtgta atgcaggatc
    40261 caatcctttc aatcattttg tccaactttt ggaggttcct acaatgtagt cgtcattaat
    40321 aaagacagat gggaacgaca gtgttcctat ttattttgat agagatcgat gaattcttta
    40381 gatagcaact gaataatctc tgttgaagcc atttggtctt ctgcatgcat aaatagcaag
    40441 gagaatccta ttttttctcc agtagcttct ttttgtatga gattggagtg aatcttgtgc
    40501 gcttctacta aggagtcttc cgcttcttca actttaattt tcgcttcttt taaatttcct
    40561 gccttagcta gttggatggc ttcaataaag gatgatttgg ctgctccact attggcaatg
    40621 agctgaaaac agatatattc catttcttct gtcatcttat ttctcctatc cattcaagtg
    40681 cttgttccag aacttttgct ccattcatca ttccgtaatc ccgcatatca atggtatcta
    40741 cagggatatt tcctgcaatt tctttcacag caagtaactc ataacgaatt tgtggcccaa
    40801 ttagaatgac atctgcttca tggatatttt ttttagcttc tgtcattgat tttgcttgga
    40861 tagaaatttc aatcccacgt tcagtcgcac tttgttgcat ttttttaaca agcatacttg
    40921 tcgacattcc cgcattacat actaataaaa tttgtttcat aatattaacc ttccatttct
    40981 tgttcaacaa ctttgtcatt aactttgata aatggaatgt atagaagaac tccaagtgca
    41041 aagatgatga attgaactag aactgctctc acgtcccctg ctgttgctaa ccatgcattt
    41101 aagaatactg gtgtagtcca aggaacttgt ataaatgcag gactcatgaa tcctgtaact
    41161 gttgctaagt agctgattaa aataccaagt actggaactg tgataaatgg aatagctaat
    41221 gaaatgttat aaacgattgg gtaaccgaat aatactggtt cattgatatt gaagatacca
    41281 ggtccaaaag ataatttagc cacgttttta gaaacagcat tgcgacttac taagaatgtt
    41341 gctattaata aacataatgt agatccacta ccacccatta aagcgaatgt ttgtatttgt
    41401 gataagttga tgatgtgtgg aatggcttgt ccattatttg ctgcagtgat gttttcagta
    41461 atgttaatta atagtaatgg ttctaggatg gcactgtaaa taactgcttg gtgaatacca
    41521 aatagccata acatatttcc taaagagtaa ataataatga ccccgattaa gcttgtacca
    41581 atatgacgaa ttggttcttg aataaagatt gtaatgattg agattaagtt cattccagtt
    41641 atattgaata ataatgctga aacaacccca aataaggaga tgacggtcat gactggaagt
    41701 aatacgctaa atgatctact aacagctggt ggaatatttt caccaaggtt catttgtaaa
    41761 gctttaacgt ttgataattc aatgaataat tctgttgcaa taatcgctac gataaccccg
    41821 gcgaacattg cgcctgtacc tgtgttgttg aatgaaagaa cacctgaaat gtttaccgca
    41881 tcttttgctc cgtcaggaac tacagaaact gtatttggca tcatcacaat taaagaaact
    41941 aatgatagca ttgatgctgc taacgggttt tcgaaatctc tgtttttagc taagaaataa
    42001 ccaaccatta cagcaataat catacctgaa atacttaaag taccgtttgc aattgttatt
    42061 ccccaatatt ggaatcttgt taatgtatcc ccttggaaaa tccacttaaa taccgtgttg
    42121 ttcaaaagaa cgattaaacc tgccaaaata tataatggca ttactgttac gaatgcatct
    42181 cttagggttt ttaaatgaat ttggttccct agtttaccag caaaggtggc aaattgatct
    42241 ataaattttg agtttttcat ctgaatatct cctctcttta ctcctcaatt tctacttcaa
    42301 aaccgttatt gtcacttact ttgcgatacc atcttcctga tctcttgatg gttctctttt
    42361 gcgtttctaa atcaacggag ataaatccgt aacgattctt atatgcatta ttccaagacc
    42421 agcaatcaaa tgcggtccaa gcgtggtatc caaaacagtg acttccctct tcaatggctt
    42481 tatgtagcca tcttaaatgt tcttcataaa attcaatacg atacacgtca tcgataactc
    42541 cattttcacc gataaaccgt gcttcgtttt caacacccat tccgttttca ctgataaacc
    42601 atggaatatt accatattct ttcttcacaa tcatagcaat atcataaatg gctttcggaa
    42661 aaatttccca accacgatat ggattcatgc gacgctccgg ccattcatac tctttgaagt
    42721 attggtctgg catccagggc gtctgatatt cctcaggatt tgcttgtgct tgaacacgtt
    42781 ttggatggta gtagtttact ccaagaaaat caaccgtatt tgatttcatc agttgaagct
    42841 ctttttcggt atgactccat aacacgccat ctctctctag ctgttttacc aatctttctg
    42901 ggaaagttcc tttaacagct ggattcaaga agactttgtt aaagaagtca tctgtaaatc
    42961 gacttgcttc taagtcttct ggagaattac ttcttggata agcaggtgtc aagtttaaaa
    43021 taatcccaat ctttccatca agtcctaatg agcgatatag ttgaatcact tttgcactag
    43081 caaggtttag attatagatg acttgtacgg cctcttttcc ctttcctttt agatttggat
    43141 aatggaaagc atataagtat cctgcttctg gaatgaccat tggctcattg aaagttgtcc
    43201 agtaatgaac cttatctcca aagcatgtga aagcagtctt ggcaaacttc acgaataact
    43261 ccactacatg tttgctttcc caaccaccgt atttttgaag aagttccact ggtaaatcaa
    43321 aatgatgtaa attcatcaca agatccatct ggttcttttt agcttcttca atgatggcat
    43381 tgtagaaagc aatacctttt ggatcaggct cacctgtctc taaattcttg atgagtcgac
    43441 tccattggat ggaagtgcgg aaagaattaa ctccaatttc cttcatcaag tggaaatctt
    43501 cggtgtaagt atgaaaaaag ttactggcta caagaggtcc gacattatcg aaaaaatctt
    43561 ctggatgcgt tttgaaccag tagtccatca cattttcatg tacttttcca tattgacctt
    43621 ctgtctgagg tccgctagaa gcagctcccc accaaaacag attaggaaat actaactttt
    43681 ttttcatgct caacctcctt tctattattc tatacataaa gtatagcata attttaaaat
    43741 ttgtctagac atttttaaaa attgttgata catatcttgt gtttgcctca tttcttgaac
    43801 tttgttatac tactattaga atattataga gagaaccaga ttaaatgagt acaaaatatt
    43861 tatttattta caatgagatt cgtgaaaaga ttctttgtaa taaatatacc atgaacgaac
    43921 aattgcctga tgaaatgaca ttagctaaac agtttgcctg tagtcgaatg acgatcaaaa
    43981 aagctttaga cttgttagtt tctgagggct taatttttag aaaacgtggg cagggaacct
    44041 ttgttctctc tcgtggcagc tcaaaaagaa aattaatcgt tccagaaaga gatatccggg
    44101 gactgacaaa aatatctgaa gatgctcatt ctacaattga ctcgaggatt attcacttca
    44161 aattagaatt tgcaaatgaa tttttagcag aaaaactaca ggtcgctttg cagagtccag
    44221 tttataatat ttaccgcctg cgtattattg acggtaaacc ttatgttctg gaacaaactt
    44281 atatgagtac cgatgttatt ccaggtatta ctgaagatat tttacaaaaa tcgatttaca
    44341 attacattga aggaaagtta ggattgcata ttgccagtgc tacaaaaatc ttacgagctt
    44401 cttctagttc agaaaatgag caacattact tgcagctcct tccaacggaa ccggtatttg
    44461 aagtagaaca agtggcttat ttggataacg gaactccgtt tgagtactcg attagtcgtc
    44521 atcgctatga tttatttgaa tttaattctt ttgcattacg acattcctcc taggagaaaa
    44581 tgtgaaaatg aagccaatct tttacagact ctagtttaag aaaaatttaa aacagggcaa
    44641 gaaggtccca tctatgctta aatggtttct cttttctaaa taagatggct ttaaaagagt
    44701 gatcgttgta tccatcatgt tgaaaaatat cttcgtatag cttatagagt aggtactgaa
    44761 attgttcacc tgatctactt cttatagtta tttagtttta aatagtgttt caaacattct
    44821 tacactgacg agaagttttt gagtcttttc ttgtaacaca tatagtatac tgtggttaga
    44881 atagtagact gtgacttcta acaaattgct agaaatgaat ttcaatctcc caatttattt
    44941 gttcatatct tcttttaata tattaaataa attctaaatc ataatcattt aaaaaaattt
    45001 tattttttat ttttcattac gaataatata gatgaagggg aaagagtatg aaaacagaac
    45061 tgtttctttt gctattagtt caaaaggaga aaaaatgaaa gtagaaaata tttcgtatag
    45121 ggtggatcat cgtaaattgt ttgataatat ttcttttgat acttcgagtt cagacgtgac
    45181 attaattact ggtaaaaatg gtacaggaaa gtcaacttta ctatagtaga ttgaaactag
    45241 aatagtacac atctacttct aaaatattgt tagaaatcga tttgactatc ctgatctatt
    45301 tgtcctgttc ttatttcatt tcactatatc tcaaattgag tatgacgaag tgcgctccca
    45361 tgtcctggga acgcactttc ttcatatttt tcatattctt gaatccatcg ataaagacta
    45421 ttgggatgaa tttttaaagt tgaactaatc atttttacag gatgagattt acagcagaga
    45481 gtttgaaggc tttatcaaag gtttttcttg gcataatgac ttttcctcgt ttccacttaa
    45541 ttttgtgtct actttattat accaagtcca cccttaagtt agataataaa tctaacttaa
    45601 ggaagctaga aggatgagaa tccaggtggt caagagtccc aaacttaagc tgatggggac
    45661 acccagaata atttgctttt tgaaggcaag gccacgttcc tctatattgg gaagtgagag
    45721 ttgaatgaga gaaccagctg atgaaaaggg tgagatatta gtagatagag cgccaataac
    45781 ggtggctgtt gtgagtaagt gaatatcaat ctgaggattt tgagcactga tgatagcaat
    45841 gatgggaaag agggctggag ctacaacgga tagggtggaa ctaaagagtg acatcactcc
    45901 ggctatcaca caaaagaaca gaggtaacca gaaatgagga atggttgttg tcatgaggtg
    45961 ccctatcagt gtgactaaac ctgacttgac cgctagagac attagtaagc tcatgccgca
    46021 gagcatgata attgtagccc agggaacctt agctaaaatg gcttcttgct tccctaattt
    46081 gagccttaag gcgaggcaga ccatgagtat tgagacaaag ccaatatcaa atgttttttg
    46141 ataagtagct atccaggcga tgtttgggaa aatgagatgc aacaagggaa aaagccaaac
    46201 caaaaccatg ctgctgatca tgagcaaggt ggtttgtctt tgaaccttgc tgaggagtgg
    46261 tggttggtca atagtcaagg atgagtttgt tcttccctta ctatagtgac tgtaacagga
    46321 taataaaagc aagacgatga gtgggtagat aatgctgacg ataaagatat gattgccaag
    46381 tgaaaaagct tgctcttccc atcccatttg cttaaacagg ccttgaaaga caatgcctga
    46441 gctactggtt atcaaattag cccctcctga agctccccaa ttgacggctt gagctccaat
    46501 caaagggtgt ttgtccgctt tttgacagag ggtaatcgct agaggacagc aaacggccat
    46561 agtagtgaaa aatccagcac ctaaagcaga caaaagggtt gccatcaggt ataaaatcat
    46621 gtagagggcg ttagggtggg tgcgtgtgcg gtagagaatg tgttgagcca aaacatcaag
    46681 agtaccgtta gttgttgcaa cgttataaaa gagagagacg ctaaaaatgg taaaaaagag
    46741 tgaggttggc caaaaatgaa gaagttcttt ggggcttaat cccatgagag tggttgcgat
    46801 gaggtaagaa aaagcaatag ccagcaggcc aatattgatt ttggtgcggt aaccaattcc
    46861 aatggctaga gcaatggcgc taatcattat taaatgaatc attgaattgt cctttcagtt
    46921 agaatatgga aataggttgg caattttggc gctcaaaaga ccacctgttt cctattggta
    46981 cttgactatt atacacaaaa aaaatacaat tgtcttgaca attgtattga cacttgttag
    47041 aattaaaaat gaggtattca ggcttgtgat ttcctatgga agttaatagt gattgcctct
    47101 aatgcttaca agtgatatta aaaatagagg acctagtgat gtcaatcatt tcaactgatt
    47161 taaccccttt tcaaatagat gatacattga aagcagcctt gcgagaagat gttcattccg
    47221 aagattacag taccaatgcc atttttgatc atcatggcca agccaaggtg tcgctttttg
    47281 ccaaggaagc tggtgtttta gcggggctaa ccgtttttca aagggttttt accctatttg
    47341 atgccgaggt gaccttccag aatcctcatc aatttaagga tggggatcgt ttgactagtg
    47401 gcgatttggt tttagaaatc ataggctcgg tgagaagtct cttaacatgt gaacgcgttg
    47461 ccttgaattt tttacaacat ttatcaggga ttgcttcgat gacagctgct tatgtagaag
    47521 ccttaggcga tgattgcatt aaggtatttg atactcgaaa aactactcct aatttacgtc
    47581 tttttgagaa atatgccgtg agagttggcg gtggctataa tcatcgcttt aatttatcag
    47641 atgctatcct gctaaaagac aatcacattg cggcagtagg tagtgttcaa aaggcaattg
    47701 ctcaagcgcg tgcctatgcc ccttttgtga aaatggtcga ggtggaagtg gaaagccttg
    47761 ctgctgccga agaagctgcg gcggcgggtg ctgatattat catgttggat aatatgtcat
    47821 tggaacagat tgaacaggcc attaccctaa ttgcaggacg ttctcggatt gaatgttctg
    47881 gaaatattga tatgaccact attagccgtt ttcgtggttt agcgattgat tacgtctcca
    47941 gtggtagttt aacccatagt gctaagagtc ttgatttttc catgaagggg ttaacctacc
    48001 ttgatgtcta agttgtaaaa taaactaact ttttaaagga tgtctttcct ctagaacgag
    48061 ttttatgtca gatagtttaa acgcctcttc aaatatagta aaatgaacca aaaatagtac
    48121 acaatgtggt ataatctttt tatggcatat tcaatagatt ttcgtaaaaa agttctctct
    48181 tattgtgagc gaacaggtag tataacagaa gc
//
LOCUS       DBEROT010000012        47278 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.12, whole genome shotgun sequence.
ACCESSION   DBEROT010000012 DBEROT010000000
VERSION     DBEROT010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 47278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.12"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..457
                     /locus_tag="ACL8CG_000818"
                     /pseudo
     CDS             1..457
                     /locus_tag="ACL8CG_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(527..853)
                     /locus_tag="ACL8CG_000819"
     CDS             complement(527..853)
                     /locus_tag="ACL8CG_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343444.1"
                     /translation="MILWSFDFANDHAHAFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(1267..3147)
                     /locus_tag="ACL8CG_000820"
     CDS             complement(1267..3147)
                     /locus_tag="ACL8CG_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGS1343445.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3141..4010)
                     /locus_tag="ACL8CG_000821"
     CDS             complement(3141..4010)
                     /locus_tag="ACL8CG_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS1343446.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSIPTPKNLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHCFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAGKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNCNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(4093..6738)
                     /locus_tag="ACL8CG_000822"
     CDS             complement(4093..6738)
                     /locus_tag="ACL8CG_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGS1343447.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFELFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVQLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTSFTSLQLARQEGS
                     VVAIGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6829..8109)
                     /locus_tag="ACL8CG_000823"
     CDS             complement(6829..8109)
                     /locus_tag="ACL8CG_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGS1343448.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDSLLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            8280..10364
                     /locus_tag="ACL8CG_000824"
     CDS             8280..10364
                     /locus_tag="ACL8CG_000824"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGS1343449.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(10404..12083)
                     /locus_tag="ACL8CG_000825"
     CDS             complement(10404..12083)
                     /locus_tag="ACL8CG_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGS1343450.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12838..14067
                     /gene="arcA"
                     /locus_tag="ACL8CG_000826"
     CDS             12838..14067
                     /gene="arcA"
                     /locus_tag="ACL8CG_000826"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGS1343451.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDESKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14125..15141
                     /gene="argF"
                     /locus_tag="ACL8CG_000827"
     CDS             14125..15141
                     /gene="argF"
                     /locus_tag="ACL8CG_000827"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGS1343452.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            15306..16253
                     /gene="arcC"
                     /locus_tag="ACL8CG_000828"
     CDS             15306..16253
                     /gene="arcC"
                     /locus_tag="ACL8CG_000828"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGS1343453.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16462..17973
                     /locus_tag="ACL8CG_000829"
     CDS             16462..17973
                     /locus_tag="ACL8CG_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGS1343454.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17995..19326
                     /locus_tag="ACL8CG_000830"
     CDS             17995..19326
                     /locus_tag="ACL8CG_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGS1343455.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPGKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            19421..19504
                     /locus_tag="ACL8CG_000831"
                     /pseudo
     CDS             19421..19504
                     /locus_tag="ACL8CG_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19731..20018)
                     /locus_tag="ACL8CG_000832"
                     /pseudo
     CDS             complement(19731..20018)
                     /locus_tag="ACL8CG_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
     gene            complement(20006..20257)
                     /locus_tag="ACL8CG_000833"
     CDS             complement(20006..20257)
                     /locus_tag="ACL8CG_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGS1343456.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQATE
                     TSSALISSHYLDEQDLSEKLKSELQWLELENKLLNLWEH"
     gene            complement(20656..21540)
                     /locus_tag="ACL8CG_000834"
     CDS             complement(20656..21540)
                     /locus_tag="ACL8CG_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS1343457.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21685..22836)
                     /locus_tag="ACL8CG_000835"
     CDS             complement(21685..22836)
                     /locus_tag="ACL8CG_000835"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGS1343458.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22982..24748)
                     /locus_tag="ACL8CG_000836"
     CDS             complement(22982..24748)
                     /locus_tag="ACL8CG_000836"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGS1343459.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24805..27921)
                     /locus_tag="ACL8CG_000837"
     CDS             complement(24805..27921)
                     /locus_tag="ACL8CG_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGS1343460.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(27931..30225)
                     /locus_tag="ACL8CG_000838"
     CDS             complement(27931..30225)
                     /locus_tag="ACL8CG_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS1343461.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(30284..31084)
                     /locus_tag="ACL8CG_000839"
     CDS             complement(30284..31084)
                     /locus_tag="ACL8CG_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1343462.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(31081..31854)
                     /locus_tag="ACL8CG_000840"
     CDS             complement(31081..31854)
                     /locus_tag="ACL8CG_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1343463.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(31879..32349)
                     /locus_tag="ACL8CG_000841"
     CDS             complement(31879..32349)
                     /locus_tag="ACL8CG_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1343464.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(32340..32771)
                     /locus_tag="ACL8CG_000842"
     CDS             complement(32340..32771)
                     /locus_tag="ACL8CG_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1343465.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(32764..33204)
                     /locus_tag="ACL8CG_000843"
     CDS             complement(32764..33204)
                     /locus_tag="ACL8CG_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGS1343466.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(33216..33854)
                     /locus_tag="ACL8CG_000844"
     CDS             complement(33216..33854)
                     /locus_tag="ACL8CG_000844"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGS1343467.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(33969..35372)
                     /locus_tag="ACL8CG_000845"
     CDS             complement(33969..35372)
                     /locus_tag="ACL8CG_000845"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGS1343468.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            35548..36321
                     /locus_tag="ACL8CG_000846"
     CDS             35548..36321
                     /locus_tag="ACL8CG_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1343469.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(37143..38648)
                     /gene="adcA"
                     /locus_tag="ACL8CG_000847"
     CDS             complement(37143..38648)
                     /gene="adcA"
                     /locus_tag="ACL8CG_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGS1343470.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVPNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(38658..39464)
                     /locus_tag="ACL8CG_000848"
     CDS             complement(38658..39464)
                     /locus_tag="ACL8CG_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGS1343471.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(39457..40161)
                     /locus_tag="ACL8CG_000849"
     CDS             complement(39457..40161)
                     /locus_tag="ACL8CG_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS1343472.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(40161..40601)
                     /gene="adcR"
                     /locus_tag="ACL8CG_000850"
     CDS             complement(40161..40601)
                     /gene="adcR"
                     /locus_tag="ACL8CG_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGS1343473.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(40756..42024)
                     /gene="dltD"
                     /locus_tag="ACL8CG_000851"
     CDS             complement(40756..42024)
                     /gene="dltD"
                     /locus_tag="ACL8CG_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGS1343474.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(42017..42256)
                     /gene="dltC"
                     /locus_tag="ACL8CG_000852"
     CDS             complement(42017..42256)
                     /gene="dltC"
                     /locus_tag="ACL8CG_000852"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGS1343475.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(42270..43514)
                     /gene="dltB"
                     /locus_tag="ACL8CG_000853"
     CDS             complement(42270..43514)
                     /gene="dltB"
                     /locus_tag="ACL8CG_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGS1343476.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(43511..45061)
                     /gene="dltA"
                     /locus_tag="ACL8CG_000854"
     CDS             complement(43511..45061)
                     /gene="dltA"
                     /locus_tag="ACL8CG_000854"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGS1343477.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIAQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(45082..45213)
                     /locus_tag="ACL8CG_000855"
     CDS             complement(45082..45213)
                     /locus_tag="ACL8CG_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGS1343478.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(45527..46704)
                     /locus_tag="ACL8CG_000856"
                     /pseudo
     CDS             complement(45527..46704)
                     /locus_tag="ACL8CG_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
BASE COUNT        14104 a        10307 c         8546 g        14321 t
ORIGIN      
        1 gaagtaaaaa tcaatcgccc taaaaaaaca attagcgaat cattctggta aaaagaaatt
       61 tcacgctatg aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttggatat
      121 cactgtgaac tattgtcatg atatgaagtt gttcaaaatg agttgcagaa atatcggaca
      181 agctggtaaa atcttggctg acagtggtta tcaagggccc atgaagatat atcctcaagc
      241 acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gctgaagata aagcctgtaa
      301 ccatgcgcta tccaaggaga gaagcaaggt tgagaacatc tttgccaaag tagaaacatt
      361 taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc ttcggattac gaatgaattt
      421 gattgctggt attatcaatc atgaactagg attctagttt tgcaggaagt ctattgaaat
      481 actaagccta cacagactga ttccaattgt tttttagatt tcaattttac cattcttcat
      541 agtcaaaacc atcataatct ggatattgtt ctggcgacgt tccaaccgaa cgtacgagat
      601 aagcttcttc gtcctctgtc tcgatttctc tcagcacttg gcattcaaaa cgccattcat
      661 caccgaagtc gaaaataaac ttaaattttt gtttgacact taggctatcc agatagacat
      721 tttctgtgta acgttcttca acatcgtcac taacaaagct aagaaagtaa gaatctgcat
      781 gactccactc aacattatcc atgaaaaatg cgtgagcatg atcatttgca aaatcaaaac
      841 tccataaaat cacatctgct agttccgcta acgtttttgt ttttggaatc tatatatgtc
      901 ggtagcaacc ttttttaaat ttgacggaaa tgatccaagc ttctacagat gctggctttt
      961 cagcttctat ttcttgtttt actaatttta agtgtagcat aatacctcca attgctcatc
     1021 gatagaattg ctcttaggaa acattcactt tctgctattt tatcataagt ttgtctaact
     1081 gtagcatttg aaaccagata attcttctgt ttcacgcgaa acaccctgcg ccaagcaagg
     1141 tgttcttgtt tttatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1201 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1261 agagtattaa gtcgtataaa tcgtcgacgc tgtcgcaatg gtatgccact ggttggctgt
     1321 agttgctgcg aaatccttgt ctgcgtagaa gtcagtaaat ggtaggattt caacttccag
     1381 ctcgtcgatg cggtcaagct gaccagccag ataaacctcg atacggcttt ctgctcgttt
     1441 gatgcgttgc aagagtccgc ccatacggat gtcaactgta tccaaaccaa agaccttgtt
     1501 ttctttcagc cattggtgac taaagagggc atggaagtct tcaatttggc ttctaagttc
     1561 tggtaattct tgtctggcga tttgttgtaa actttcttta tcatccgctt ggtaggcctg
     1621 acgaatgcgt cgtcccacat ctactttgct acttaaaata gcattcaact gggcctgagt
     1681 ttcaaagaga taggcatagt ttccagcttt ttctttaatg ttagcaagcg tctcagcagc
     1741 ctgagcgaag tgcggtttgt cctgttcagg tgtcatgtgt tgatcaagaa tcggacaaag
     1801 aatatcctga taaaaaacat agcggttggg attgataccg ctgagattgc ctggtaggtc
     1861 tggtaagagg ttggcaaggt caatctgcat aaaatcctca accgttagac cagtattggt
     1921 cttgaagtgc gcagacaaac catctaggtc attgcgatag ctgagttctg cccagatttg
     1981 caagcttggt aggatagaga actgggcagt ttcaccacca ttgtctcccc aacccgttac
     2041 gatgacttct ttaatctgat tggcacggca ggctttatta gcctcgatag ccactagacg
     2101 gctaaaatgg ttgtgaggtg taaagccaat ccacttccaa gctccccctg caaatgcaag
     2161 gtcatggcta atcttgtgat gattgcggaa attacggttg tatttttcct cgctatcctg
     2221 ataataatcc cagtaaacca gagtcacacg gtctttgaga cggtctaggt agacacgagt
     2281 ttcctctgga atttccacat cacggtcgta ctggccatcc gctgacatga gtttgaagaa
     2341 catatcactc cacatctggc agtggaaacc atatttgtca gcaatatcca gcacgcgctc
     2401 caagtgttgg cacatgagga gactacgatc cacaacaccg ttcaaaatca ggtagcgtcc
     2461 caaaccaacc aagtgggctt cgtccatccc gatattgacc ttgcgagtct tcagtttaga
     2521 caacgtggca aacatgccat caatcaggtc ataaaccttt tcttcgccaa tgagaagaat
     2581 gtcctctaca tcacggagct cctgcacttc cttgacaccc catttgacaa aggccgacaa
     2641 gtgggccaag gtctggatgc atggtacaaa ggtcatgtca aactgttgag cataggcttc
     2701 tatttcctgc aactcctctg ctgaataagc tccacggaaa tagccaaagt aaggctgtcc
     2761 ttcaatctgg taagtgtctt ccatgtaaag ctcaaaggtt gagtagccca tgagagccaa
     2821 gacctcaatc atctgcttgg cagaagccac attcagcacc gcatttcgag aacagtcaac
     2881 catgtaagcc aaatcttcgt aagctgcttg ttcctcaatc tctactttat cagcttctgc
     2941 tagaactgtt accaacaagg ataaggcacg ataaagttgg tgaggtttgc ggtaggtcaa
     3001 ttgatagtga ccttcctcac cctggataga gatagaggct tggtcagact gagtgacagc
     3061 cacttccaca tctggtagag aaatgtgacc ttttaaaacc tcaatagctt gcgtttgttt
     3121 gggactaagt cctgtaaatc ttaccattgc ttttcctcct gtagccagtt gacaagagca
     3181 ccgtagagat tggcatctgc gtgataggtg caggcctgga taactggtgc gaccgtgtat
     3241 tcttcgtagg catctacaaa gtcttcaaca gccttcttaa caccttggat aaaatctgga
     3301 ttttgactga tagagccacc cagactgatg acatctggat cgatcagata ctggatattg
     3361 agcaagcctt gcgccagatt gcagttcatg cgctcaatgg cttcttgaca aagagcatta
     3421 ccagctgcgg cctcttggta aatcttgcga ccgtcccaat cagtatgacc agatttttca
     3481 attacgtatc gtaccatatt cccagttgat gctagttgcg accagttatt aagttttcca
     3541 gcaggggcaa gggttgtcat gtagccaaat tctccaccca gaccgtggcg acctcgatga
     3601 agtctaccat tgataatcat ggctccgcca atccctgtcc caatcacgac acaggctgca
     3661 ttttcaagct ctggatgagc tagtagttca ctgagtccaa cgcagttggc atcattttct
     3721 aaatggacag gtagctgata agagctaagc gcctcatacc aagaaaagca atggatgtag
     3781 ggcaccgcac tgaagccatc aatcacacct gtctcttgat tgaccgcacc tggaacgctc
     3841 atagcaatcc cactataatc ctgttctgac aaacgttgat ctagccaagc tagtaagtcc
     3901 tccaagtttt ttggtgttgg gatacttgtc ttatctagta ttttcccatc aggagtcaga
     3961 ctagcaaact taatcccagt ccctccgata tcaatcgttg caatggtcat ttttttacca
     4021 taaaaagggg caaatcagca gttagttctt accttttcgc ccctcctttc ttttgatgtt
     4081 tactttttga aattaaattt cttctttttt gatgaattct gtacgaatct cttgtggagc
     4141 caatagtcct gaatgaactg gatatggtcg ctcaagtaag tcaagaatgg tttgttgatg
     4201 ttctgatatg cgcacatttt cttgactcat attatagtaa cggaggacat agccttcttc
     4261 attttccgcc actttaaagg ctgttggaca aacttgcggt atgctgagaa cagaatggct
     4321 caagaggcta ccaatcgcaa ccacgcttcc ttcctgtcta gcaagctgaa ggctggtaaa
     4381 cgatgtctgc aaggctttgg cacgacgata ggctgagaag cgttcttggg cttggtggca
     4441 ttcaagtgca aactcgactt caaactcccg caagcattgt gcttctggcg ttgggaagta
     4501 gccccagtca cctagctcac ctgatgcacg caaaatggtc acggcaatgg tgttatcccc
     4561 aaggatttcg tattcattca atcccttatt ggatacagtc accccttttt catcgtcata
     4621 cagactgaca aaagcttgtt ggtgttgagg attttcagga ttttcccatg aagcagctgg
     4681 tttgtttggt cgtgtcacca cctcatagat actttcagaa tcattacttg gacgcgtgtt
     4741 atgagtcttg accaagagac ggatacggtg atccttggca gtgttggtaa agcgagtctt
     4801 gaagcggatt tgtggattgt caacgaagac agtcaactca gtttccagag gaatgtttgt
     4861 caattcttct gaccgtccag cctcacgctt cataaactcg atgatacctt gttgctcttc
     4921 ttctagcttt tcatccgcgc tgacaggcac ggtcaattca tgtttgagca agattttagc
     4981 atagcaagct gtgttttcca agacctcgtg gcccttaagc tctgcaaaga ttggctctgt
     5041 tccttttggt tggaaataga tatactcgtt tccgatgtcc ccacggtctt caaagcggat
     5101 aaagtcttca taggcttcgt gagttgtctt gtcatagact gtgatgttgt catccacact
     5161 caccgttacg aatggtgtat caatcactcc gttttggtaa ataccctcac ggtgttcttg
     5221 ttttccttcc agcaattgga aggttgtcca agaaagcggc gctagctgaa ctggaatggt
     5281 cacgcgcact tgtcgagcaa tacgagcttg gcggaacttg tcttttggta aatcgtattc
     5341 aaaattagct ccgaggtctt cgattgtagc ctctacagga cgaccatcca agtcctccac
     5401 acggtaactt ggcaagataa gagcggccat ctttttgtag ccttctgttg ggtgcaattc
     5461 cttgaaatca caagtcgcca catcaatcac tgtgctgaca gtatcgacct tatcatgcaa
     5521 gcctgtgtta atgacagtaa agagatagtc actttgagcc ttatccgtag caattttacc
     5581 cttccactcg ttgagcaaat tacttttaac aaagtttcct acttggttga ccttggcaaa
     5641 acgcgtttcc atctcgcggt gaacttcgtc cacgctacag ccacagatac tatcatgtgg
     5701 cgcattctgc aaaagtgttt tccaagcata ggtcaactgg tccttgtggt tgtgtccacc
     5761 agtgataata gtcaagggtt ctaccacttg ctctaggagg ttgctatttt cttggaaggc
     5821 ttgttttagg taaatgcggg atgaagaagt gttggcaagt gtgtaccagc catctgtttc
     5881 ctgactggtc aactcgcctg taacagttga taagtgttca ggaagcgcac cttctacagc
     5941 ttgaacatat tcatcaaaag aactatgaac aaagattaca tctgggaaga gttcatttgc
     6001 cacacgaatg gcttcgctca gatttttctg tacaggctgg tggtcacagc cgttcatcat
     6061 caaccattgg ttggtcgaag cgtaggcacg cacatctgac aatttttgtt tccagaaggt
     6121 caaggcctca tctttgtcaa ctgggatttc attcccatta ctgtaccagt tagcaaagag
     6181 aatacctaaa acacgactac catccacacc ctgccagtac atttctgaaa actgggatgt
     6241 aaactgctca tcttcaagga cttggttgtc aaatccaatc ggcttcacac cacgaccaaa
     6301 ggccgccacg tgaatgcctg atttttgaag aatttgaggc gcttgtccca tatttccaaa
     6361 ggtatctgga aagtagccaa tctgggttga tttaccccat ttggcagctt cttgttgacc
     6421 aatcaaggta ttgcggacat tggcttcact ggagatcaag tagtcatcct gcaagatgta
     6481 aaagggacca attttaagtt tgccctcgtc aatgtagcgt tggaccttgt cgcgattttc
     6541 agggcgaatt tgtaagtagt cgtcaaggac aatagtttgt ccatccaagt ggaaactctt
     6601 gaactcaggg tcattttcaa agagttcaaa gagattgtca aacaattcca ccaactgcat
     6661 acgatggctt tcaaaaggca agtaccactc acggtcccag tggctatgtg agataatatg
     6721 tacaacaaca ttttccatga agtaaaacct cattctaaat ttaaatttta acgttttaaa
     6781 tgtaaacttg tgattctgat aagaatcggt tgagctaaag cgagcccctt agcgaatatc
     6841 taaataatcc aagaccaact cacagaacat catgttagcc caggagaacc attcacgaga
     6901 gtagagggtc ggatcatcta cgtggaagct ttcgtgcatg acacctgtac caccatcgca
     6961 ggcaaccagc tgatccagca agaatttttt ctctgcctta tctcttgttg tcaatccttg
     7021 gatagaaagg gcgattggcc agatatagcg atagaaggta tgagaacttc cgagaccgct
     7081 agcgtattct ccttggtaga aatatggatt ttcagagctc aaaatggtac gacgagtagc
     7141 ttgatacact tcatcatcga ccgaacagta gcccagatag ggcgcagcta gtagacttgg
     7201 tacatttgga tcatccatga tgctggcatt tcctaggcca tccacttcaa aagcgtaaat
     7261 cttttcgccc ttgctgttgg tggtgtaagc gtagttttcg attccttctt ggatttcatc
     7321 ctgaagacgc ttggcatcag caataacact ctggctatca gctaggttta atgctgcgaa
     7381 gatttcttgc acataaccca agactactac agcaaacata tttgacggaa tcaagtaact
     7441 atactgacag cagtcatcgc tcggacgaaa ggctgaccaa gtcattcctg tcactgcaaa
     7501 atcaggtcca aagccatcat ttaccaaggt gtcttccttg cggtccgtat ctcggacaaa
     7561 acgataagga gagttcttat gatcttgttc taccgtccac agatggagaa tttccttagt
     7621 cgctgcgaca aaaatctcat caaactgact agtctcgcca gtctctttcc agaggagata
     7681 agccaactgc aaaggatagc aaagcgaatc cacctcatac ttgcgctccc agatccagcc
     7741 gttaaggtct gtgtggtcag tctcgtggtg ccctttccag ttctcctcaa tgttgaagga
     7801 gttagcatag ggatccttga gtaccaaggt catctgacgt ttgaccaaac ctgcaatggt
     7861 ctgacgcagg agggaatctc ttttagccac atgcaggtag ggtctgagtt gggctgtcga
     7921 atcccgaagc cacatagcag gaatatcccc agtcaagaca aaagttgaac catcttctaa
     7981 gatttcaacc gtattgtcca aggtatcggt gtagcaacgc tcgaaaacat ccacccactc
     8041 tggatggtcc ttggcccgct ctgctacttc atctagccat tctctaacaa tttctttcga
     8101 ataaatcatc gtgcaattcc ctctttcaaa caagtttcat gttcagtata tagcttttga
     8161 gacagaaaat acatacacaa atgatagtca tttttctaca aaatagttat ttttgaaact
     8221 ccttttctaa aggccctctt tttctgatat aatgtagaaa aacagctaaa ggaaagacta
     8281 tgaaaccact acttgaaacc atcgataccc gctttggtac tgctagcaag catgccttct
     8341 ctcggggaaa taccctgcca tacacaggcg tgccttttgg tatgaattac tttgtgcccc
     8401 agaccagtga ccaggatgga tcttggtttt ttgatccgca tctgcctatc tttcagggga
     8461 ttcgattaac tcaccagccc agtccttgga ttggggacta ctcttggctc cttctgacac
     8521 ctgtcaccag tcaactgggg ggagacagcc tctttcaccg ccagtcttct tatgatatag
     8581 ataaagcttg cttccagcct cactatttga agctcttttc tctgcgttat cagattgaaa
     8641 cccagctcac accgacttgc tatggtgctt ctattcgttt gaatcaaaag caaggcaaag
     8701 ccctctccct ctatcttcac gcagcagatg aactgacagt agagcaagta gataagcgga
     8761 ctcttgccct gcgacaagaa ggtaaaactg aaactaacaa aaattcgcta acgatgttca
     8821 ctgccctgca aatgaacacg gatattcttg ctatcagcca agaagctgga gactggcgaa
     8881 ttgacttagc aagtagtcaa accgagatgc aactagccac ttctttcatc tctccttctc
     8941 aagctctaat caatctacct caagaagatt ttgatagctg taaaacaagt gcccaagcgg
     9001 attgggaaaa tctcctccat cgttttgaca ttatagagac aggagaggct gaccgaacct
     9061 tctttgacca ctgtctctac agactcttcc tcttcccaca gactttttat gaggttgatg
     9121 agtcagggaa agccatccac atggatctgg ctactggtac tgtcaagcct ggtgtcctct
     9181 ttagcaacaa tggtttctgg gataccttcc gcaccacctt ccccctcttt gcccttatca
     9241 taccggagca ctatcaacgc tttttagaag gtttcctcaa tagctaccgc gatactggtt
     9301 tccttccaaa atggctggct ccagatgaac ggggtatgat gccaggtaca ctgctagatg
     9361 gcattatcgc agatagcgcc tgtaaggaca tggcccccga cctagaagga gaactcttcc
     9421 aagccatgct cgaaacagcc agcaaagccg accctctcgg catcaatggc cgccacggac
     9481 tagcccaata ccaagaacta ggttacctct ctaccgacca ccatgaaagt gttagccata
     9541 ctctagacta tgcctatagt gacttttgta tcgccagctg tgccaaaaaa ctagagaaca
     9601 tagaaatcgc tgaaacctac aaggctgctt cacaaaatta ccgccagcta tttgacgctg
     9661 agacaggtta catgcgagca cgagacaatc aaggaaactt tcaccctgac ttctctcctt
     9721 atagttgggg gcgagactac gctgaatgct ctgccattca agctacttta ggcgttctcc
     9781 acgacatccc tggcttaatc caactgatgg gtggaaaaga aacctttagc aactatcttt
     9841 tgaaagcctg tcaagatgct cccctctttg aaacaacagg ctatggttat gaaattcacg
     9901 aaatgagcga gatggctact gctccttttg gacaaatagc catttccaac cagcctagtt
     9961 tccacatccc ttatctcttc cgctacagcg attaccctga ctacactgcc cttcttatca
    10021 agacgctccg tcagaaagct tttcacccaa gttgggaagc ctatcctgga gatgaagaca
    10081 atggtagtct ctctgcttgg tacatctggt cagctctcgg attttatcca acctgtccag
    10141 gaaaaccaag ctatgacctc ggaatccctc tctttgacca tctacgagtc tacctagcta
    10201 aagaagataa atggctggat atccatacta aacaaaacca caaccatttt aactttgtca
    10261 aagaatgccg actgaacaaa acactcgtat caactattca acaccaagac ctcttaaaag
    10321 ctgaacaact aactttcacc ctcagctggc taccaagtca ctaataacca aaagaacctt
    10381 tgcatcgcgc aaaggttctt cttttatgaa acttggactt gaagttgatc cacaagctga
    10441 ccatccaccg ttaggttcag atagaaatcc aaggttttat ctcctgcgaa atacagggtt
    10501 ggtagatgca aatctttttt gctttcccct gcttggaatt gaaggacata aatctcgtcc
    10561 tgataggcga caccatggac acctgtcccc ggttgaatcg aaatcttagc ttctaaagga
    10621 ccactacatt ctctgcgctt aactgtaaaa taggcatttt ctccctttgc cacagctagg
    10681 cttttttctg caaatgctag ttcctgaaca acttcttttt ttgataatcc aggagtttta
    10741 taaagggaaa tcttggtcaa tacaggaata gattgtgcct cggtaatcat cacgcgcacc
    10801 ttttgtgcct ctactagcga acctcgcaag aggcgcttat gaccaactgt gaagcccctg
    10861 ccaaattcct gccagacacc atccacctct acttgcacat ggaaagcaga aatacgttgg
    10921 cctaacttca aatcttctct caactcaatt acatcaaaag ttttaggaga acctaagtcg
    10981 agttctaact ggatgggcaa gtctgcatcg tttgcccaag agctggtctc aaggccgtct
    11041 gtcaaatggc gacaagcaaa gtctgcggaa agagctggac cagatacctc agctcccaga
    11101 gccaaatctt ctttatagag ctcattgcga taggtcgcaa attcataaag tcgttcaata
    11161 tcctttgcat caaagagccc agcttgattc ggcggaatat taagcaagag tggagttcct
    11221 cgccctactg agtgaaagta gatttcgacc aactcctcga gagacttagg atcctgatcc
    11281 tcatggtaga accagcctgg acggatggaa acatctgcct ctccgattga aaaaatcgtg
    11341 cccgagggat ccccgtgctg aagatagttc agctctgctt ctgttcctag tttatcagga
    11401 ttcacctttt gccacagtgg atcacctgca taccctcgtt cattgccaat ccagcggata
    11461 ctggtgcctt ctgttgaaaa aatcaagcaa tcgccctgca ggtcacgaat ggtttcaaac
    11521 catttttcaa attcataatt aaccttttgc gcgccctctc ctctggcacc atccatccaa
    11581 acctcagcga acttaccagc attcccatag ttaggatttg ataagatttc cttcaactga
    11641 gccagataat aggcattgta gtccgcttct cggtccacat gatagagggg actatgggca
    11701 tcccacggtg acaggtagac ccccatatcc atatcaaact ctgtggcagc ttgggatact
    11761 tcaaggagca agtcgccctt tcctctcctc caaggactga ccttaaccga ataatctgtg
    11821 tgagctgtcg gataaaggac aaagccatcg tggtgcttga ccaccaaaat caactttttg
    11881 aagcccgttt ccttgagcac acgaacccac tcacgcgcat ccaactgact cgggttaaag
    11941 cgctcaggat cctcctgtcc agtcccccat tcttggtcat aaaaagtatt aggaccgaag
    12001 tggataaaag ctgctagttc atctcccaga taagctagct gagtctgact tggtaacggt
    12061 ccatgcggtt tgattttctt catcgttata tatctccttc tttagcaact tctcttgttc
    12121 acaaggttat ccacaggttg tggataataa accatgatct aacagccagc tctttccaac
    12181 tccaactggt aggctcagga ttttgctcct caatattccc tcttcaaaca gctctgtcat
    12241 atggttctgc taacacctct cagaatgcta ctctccataa ttattctcag gcttctttca
    12301 ggtcattgtg tgaagaccat tcactctcca gacttttcca cagattgtga ataagtgatt
    12361 attctaaact atcacctcgt cgactataac aaaaaataaa aagagggtca ataagataat
    12421 tatctcttcc taaatactca gaaaagattc tataatttgt acaattgaac aagaaatgct
    12481 tctccaaaat ctatcttcaa aagaatgttg catcttttta tcctttcaca caaacatttc
    12541 tctttataca gatccaagtg ataaccagat gataattgga cactttttgg tcatttgtat
    12601 attttttgaa aaatttttta aaaaaatttt atatcctttt tatagaagtt tatgcatttg
    12661 tatctatgta ttctatccta tgttatgtat aataacataa aattgtgcta aacatcataa
    12721 tttatattat tttccgagaa attatagcca ttgacattac ctaggaattg cgttataaca
    12781 tacatgtaag cggtacccaa aatggtgcca agtcaaaatt tttaaggagg aaaatacatg
    12841 tcttcacatc caattcaggt cttctcagaa attgggaaac tgaaaaaagt tatgttgcac
    12901 cgtccaggca aggagttaga aaacttgttg ccggactatc ttgaaaggct tctttttgat
    12961 gatattcctt tcttggaaga tgctcaaaaa gaacatgatg catttgccca agctcttcgc
    13021 gatgaaggaa ttgaggttct ctacctagaa caactcgctg ctgaatcatt gacctctcca
    13081 gaaatccgcg atcaatttat cgaggaatac ttagacgaag ccaacatccg tgatcgtcaa
    13141 accaaggttg ctattcgtga attgcttcac ggcatcaagg acaaccaaga attggttgaa
    13201 aaaacaatgg ctgggattca aaaagttgaa ttgccagaaa ttcctgacga atctaaagat
    13261 ctaactgact tagttgaatc agattatcca tttgcaattg acccgatgcc aaacctctat
    13321 ttcactcgcg acccatttgc aacaattgga aacgccgtat cgcttaacca catgtttgca
    13381 gacactcgta accgtgaaac actctacggt aagtatatct tcaaatacca cccaatctat
    13441 ggcggaaaag tggatttggt ctacaaccgt gaagaagata cgcgtatcga aggtggagac
    13501 gagctagttc tttctaaaga cgtccttgca gtaggtatct ctcaacgtac agacgcagct
    13561 tctatcgaaa aacttttggt caacatcttc aagaaaaatg ttggcttcaa gaaagttttg
    13621 gcctttgaat ttgctaacaa ccgtaaattc atgcacttgg atactgtctt cactatggta
    13681 gactatgaca agttcactat tcacccagaa atcgaaggcg accttcacgt ttactcagtt
    13741 acttacgaaa acgaaaaact taaaatcgtt gaagagaaag gtgacttagc tgaacttctt
    13801 gctcaaaacc ttggtgtaga aaaagttcat ttgattcgtt gcggtggtgg caatatcgta
    13861 gcagctgcgc gtgaacaatg gaacgacggt tctaacactt tgaccatcgc acctggtgtg
    13921 gtagttgttt atgaccgcaa taccgtgacc aataagattt tggaagaata cgggcttcgc
    13981 ttgattaaga ttcgcggaag tgaattggtt cggggccgtg gtggacctcg ttgtatgtct
    14041 atgccatttg aacgtgaaga agtgtaatcg ctgttcggta ttcgtcaata gaaaatgtaa
    14101 aaaatagaaa gaggaaataa taaaatgaca aattcagtat tccaaggacg cagcttctta
    14161 gcagaaaaag actttacccg tgcagagtta gaatacctta ttggtctttc agctcacttg
    14221 aaagatttga aaaaacgcaa tattcaacac cactaccttg ctggcaagaa tatcgctctc
    14281 ctatttgaaa aaacatctac tcgtactcgt gcagccttta caactgcggc tatcgacctt
    14341 ggtgctcacc cagaatacct cggagcaaat gatattcagt tgggtaaaaa agaatctact
    14401 gaagatactg ctaaagtatt gggacgtatg tttgacggga ttgaattccg cggattcagc
    14461 caacgtatgg ttgaagaatt ggcagaattc tcaggcgttc cagtatggaa cggtctaact
    14521 gacgaatggc acccaactca aatgctcgct gactacttga ctgttcaaga aaacttcggt
    14581 cgcttggaag gcttgacatt ggtatactgt ggtgatggac gtaacaacgt tgccaacagc
    14641 ttgctcgtaa caggtgctat ccttggcgtc aatgttcaca tcttctcacc aaaagaactc
    14701 ttcccagaaa aagaaatcgt tgaattggca gaaggatttg ctaaagaaag tggcgcacat
    14761 gttctcatca ctgaagatgc tgatgaagca gttaaagatg cagacgttct ttacacagac
    14821 gtttgggtat caatgggtga agaagacaaa ttcgcagaac gtgtagctct tcttaaacct
    14881 taccaagtca atatggactt agttaaaaaa gcaggcaatg aaaacttgat cttcctacac
    14941 tgcttgccag cattccacga tactcacact gtttatggta aagacgttgc tgaaaaattt
    15001 ggtgtagaag aaatggaagt aacagacgaa gtcttccgca gcaagtacgc tcgccacttc
    15061 gatcaagcag aaaaccgtat gcacactatc aaagctgtta tggctgctac acttggtaac
    15121 ctttatattc ctaaagtata attttagata ataaaccgtc taccaacagc tatgagggct
    15181 gcgactaata gctttagtcc ggtcctcttt tatataatgg taatctatta tttcttataa
    15241 aatatgtgaa aaatcattaa attgaaatct aaacgcattc tattgagtgt gataaaggag
    15301 aatttatggc aaatcgtaaa attgtagtag ctttgggagg aaatgcgatt ctttcttctg
    15361 acccatcagc aaaggctcaa caagaagctt tagttgaaac agctaagcat cttgtaaaat
    15421 tgattaaaaa tggagatgat ttgattatca ctcacggtaa tggacctcaa gttgggaatc
    15481 tcttgctcca acatttggca tcagactctg aaaagaaccc tgccttccca ctcgactcac
    15541 ttgtcgctat gacagaaggt agcatcggtt tctggttgaa aaatgctttg caaaatgctc
    15601 tcttggatga aggcatcgaa aaaaatgttg cctctgttgt aacgcaagtt gtcgtagata
    15661 aaaatgatcc agcttttgtt aacttgagta aaccaatcgg tcctttctat tcagaagaag
    15721 aagcaaaagc agaagccgaa aagagcggag cgactttcaa ggaagatgct ggccgtggct
    15781 ggcgtaaggt cgttgcctca ccaaaacctg ttgacatcaa agaaattgaa accatccgta
    15841 ctcttttaaa taatggtcaa gtcgtcgtag ctgcaggtgg tggcggtatt cccgtcgtca
    15901 aagaaaacaa tggacatttg actggtgtcg aagcggttat tgataaagac ttcgcttccc
    15961 aacgtttggc agaattggtt gatgcagacc tcttcatcgt tttgacaggt gtagattatg
    16021 tatttgttaa ctacaacaag ccaaaccagg aaaaattgga acatgtgaat gttgcccagc
    16081 tggaagaata tatcaaacaa gatcagtttg caccaggtag catgcttcca aaagtagaag
    16141 cagctatcgc ttttgtcaat ggtcgtccag aaggaaaagc agttattact tcccttgaaa
    16201 atctaggcgc cttgattgaa tctgaaagcg gaacaattat tgaaaaagga taagttgttt
    16261 tactaataag atgtattcta tttctagtat ctttatatca aattagaaat tattcttgaa
    16321 aacatgtaca atatttcaaa agatactagt tttagacttt aatatggtaa aacaaatata
    16381 aatagaaagc gttttcttga atgtttattt aagaaagtag ttggtttttt acactttgtt
    16441 agacatcagg aggaaaaaca aatgagtgaa aaagctaaaa aagggtttaa gatgccttca
    16501 tcttacaccg tattattgat aatcattgct attatggcag tgctaacttg gtttatccct
    16561 gcgggggcct ttatagaagg tatttacgag actcagcctc aaaatccaca agggatttgg
    16621 gatgtcctca tggcaccgat tcgggctatg ctaggtactc atccagagga aggttcgctc
    16681 attaaagaaa cgagcgcagc gattgatgta gccttcttca tccttatggt tggtggtttc
    16741 cttggcattg tcaacaaaac tggtgctctt gacgtaggga ttgcctctat cgtgaagaag
    16801 tataagggcc gcgaaaaaat gttaattttg gtactgatgc ctttgtttgc cctcggtggt
    16861 acaacttatg gtatgggtga agaaacaatg gccttctatc cactccttgt gccagttatg
    16921 atggccgttg gttttgatag cctgactggt gttgcaatta ttttgctcgg ttctcaaatc
    16981 ggctgtttgg catctactct gaatccattt gcgacaggta ttgcttcagc gactgcggga
    17041 gttggtacag gggacggtat cgtacttcgt ctgatcttct gggttacctt gactgctctt
    17101 agtacttggt ttgtttaccg ttatgcggat aagattcaaa aagatccgac taagtcactg
    17161 gtttatagta ctcgcaaaga agatttgaaa cactttaacg tagaagaatc ttcatctgta
    17221 gaatctacac ttagcagcaa acaaaaatca gttctcttct tatttgtgtt gacattcatc
    17281 ttgatggtat tgagcttcat tccatggaca gaccttggcg ttaccatttt tgatgacttt
    17341 aatgcttggt tgactggtct tccagttatt ggtaatattg tcggttcatc tacttctgca
    17401 ctaggtactt ggtacttccc agaaggcgca atgctctttg cctttatggg tatcctgatt
    17461 ggtgttattt atggtcttaa agaagataag attatctctt ccttcatgaa tggtgctgct
    17521 gacttgctca gtgttgcctt gatcgtagcg attgctcgtg gtattcaagt tatcatgaac
    17581 gacggtatga ttaccgatac aatcctcaac tggggtaaag aaggcttgag cggtctatct
    17641 tcacaagtct ttatcgttgt aacttatatc ttctatctac ctatgtcatt cttgatccca
    17701 tcttcatctg gtcttgccag cgcaactatg ggtatcatgg ctccacttgg agaatttgta
    17761 aatgtccgtc ctagcttgat tatcactgct taccaatctg cttcaggtgt cttgaacttg
    17821 attgcaccaa catctggtat tgtgatggga gctcttgcac ttggacgtat caacattggt
    17881 acttggtgga aattcatggg caaactcgta gtcgctatta ttgtagtgac catcgccctt
    17941 cttctccttg gaaccttcct tccattccta taaaatagtg agtgaggtga ttccatgaaa
    18001 atagatataa caaatcaagt taaagatgaa tttcttatat cattaaaaac cttgatttcc
    18061 tatccttcag tactcaatga aggagaaaat ggaacacctt ttggacaagc aatccaagat
    18121 gtcctagaaa aaactttaga gatttgtcga gacataggtt tcactaccta tcttgaccct
    18181 aaaggttatt acggatatgc agaaatcggt cagggagcag agcttctggc cattctctgt
    18241 catttggatg ttgttccatc aggtgatgaa gcagattggc agacaccgcc atttgaagca
    18301 actatcaaag acggctgggt attcggacgt ggtgtccaag atgataaagg cccttcgctc
    18361 gcagctctct atgcagtaaa aagcttgctg gaccaaggta ttcagttcaa aaagcgcgta
    18421 cgctttatct ttggtaccga tgaggaaacc ctctggcgct gcatggcacg ctacaatacc
    18481 atcgaagaac aggccagtat gggctttgca cctgactcat cttttcctct gacctatgct
    18541 gaaaaagggc ttctacaggt caaacttcat ggccctggat cggatcaact agagcttgaa
    18601 gtaggaggcg cctttaacgt tgtaccaggc aaggccaact accaaggtcc cctctatgaa
    18661 caggtttgta acgatctcaa agaagctggt tatgattacc aatccactga acaaaccgta
    18721 acggttctcg gagtgccaaa gcatgctaag gatgctagtc aaggtatcaa tgctgtcatc
    18781 cgactagcta ccattcttgc tcctctccaa gaacaccctg ctctcagctt tcttgcaaca
    18841 caagcaggtc aagacggcac aggaagacaa atctttggtg atatagcaga tgaaccttct
    18901 ggtcacctat cctttaatgt cgcaggtctc atgatcaatc atgaacgttc tgaaatccgt
    18961 attgacattc ggactcctgt cttagctgac aaggaagaac tagtagagtt gcttacaaga
    19021 tgtgcacaaa actaccaact ccgctacgaa gagtttgact atctagcgcc tctatacgtc
    19081 gcaaaagaca gtaaactcgt tagcacactg atgcaaatct accaagaaaa gactggcgat
    19141 aacagtcctg ctatttcatc cggtggtgcc acttttgctc gcaccatgcc aaattgtgta
    19201 gccttcggcg ccttattccc aggagcgaag cagacagaac atcaggcaaa tgaatgtgcc
    19261 gttctagaag atttgtaccg tgctatggat atttatgccg aagccgtcta tcgacttgca
    19321 acttaatcag gcaactgttt ctaccaaaaa aaatcgaccg attaatgaac tgcaccccaa
    19381 aagttagaca gaataaatct aacttttggg gtgttttatt atgaaattga gttatgaaga
    19441 taaagttcag atctatgaac taagaaagca aggacaaagc ttcaaacagc tttcaaaaag
    19501 atttgtgtgg atgtttctgg tctaaagtca tctgaatctt tgagatgagc tttataaatc
    19561 gcttttttca gtttttgcac tggtgtttcg ataaactcaa actttttagc cgtggtattg
    19621 cctgatttta tagtatattg aaactagaat agtacacctc tacttctaaa acatttttag
    19681 aaatcgattt gactgtcctg aacgatttgt cctgttctta tttcatttta ctatatttga
    19741 gccacttcgt ctttaacggc tttattcata agctcttgta atttttcttt actatcaatt
    19801 acttctgatt ttccgttgta atttattgta ataggtttta acttacctaa tttctcgaca
    19861 cgctcattaa tttgatcttt tttgaaggct gcatatgttt ttcctaagat tttttcgaaa
    19921 atatatttat cagatagcgg tttgtcttct tcagcttggt ttttgtatta atttgaaacg
    19981 taaggaacaa atccttcata gtaacctaat gctcccataa gttcaaaagc ttgttttcta
    20041 attcaagcca ttgcaactca gatttcagct tttcagataa atcctgctca tccaaataat
    20101 gacttgaaat tagtgctgaa ctcgtttctg tagcctgtac aggctgagca cccataccag
    20161 caaaaaataa actcgttcct agcaagaccg aacaagctcc tattgcatat ttcctcaaag
    20221 aaaaacgctg ctttctctca aattgaaatt ctttcatccc atctcccatc attcattatt
    20281 actgtatatt ttgtatatca gaaatagttt gtattcacaa atctttctag ttattccctt
    20341 atcattccta attaagggag ataacataca ataattttta gttaaatgta tatcgatgtt
    20401 ttttgttttt cttaataaac gcaatacaaa aagagcctgt tgccaagctc tttgtactca
    20461 atgaaaatca aatagcaaac taggaaacta gccacaggtt gctcaaaaca ccgttttgag
    20521 gtagtagata agactgacga agtcagctca aaacactgtt ttgaggttgc agatagaact
    20581 gacttcgtca gtaacatcta tacggcaagg cgacgctgac gtggtttgaa gagattttcg
    20641 aagagtatta gtctattatt tcttctcagc gcgaagggct gacaagattt gtgttcggat
    20701 atcatccaca ccatttggag tatttggtaa aaagatggtt tgatttcctt tagaggcaaa
    20761 ggtattcaag gtatccaaat actggttggt caagaggata gacatgattt gttcttctgt
    20821 catgccaaca ttggcttcct tgagttcggt gatagactct gccaatccat ccacaatcgc
    20881 cttacgttgt tgggcaatcc ccacaccatg aaggcggtct ttttctgctt ctgcttcagc
    20941 tgcagtgaca attttaatct tgtcagcttc cgccaattct tgtgctgcga cccgcttacg
    21001 ttgcgccgca ttgatttcat tcatggattg cttaacttct gcatccggtt cgactttggt
    21061 aatcaaggtt ttcacgataa tgtagccgta agtggtcatt tcttctgcta cttggtgttg
    21121 aacttcaagg gcaatctcat cttttttctc aaacaattca tccaaggtta attttggaac
    21181 agaagagcga agagcatctt cgatataaga tttaatctga gattctggac gtatgagttt
    21241 atagtaagca tctgtcacgc tctgctcgtt gacacggtac tgagtcgcta cattcatcat
    21301 aacgaacaca ttgtccttgg tcttagtctc aaccacaata tcactttgca acaagcgcaa
    21361 ctgaatccgt gctgcaatcg agtcaatccc aaaaggcaag cgaatatgaa taccgctatt
    21421 agcaaccttt tggtatttcc caaagcgttc aataatcgcc accgactgct gacgaaccac
    21481 ataaactgta ctcagtgtga ctatcaccaa taggagcaca caaacaatca gaaaaatcat
    21541 gaaaaatatt gccataatgg aacctccaca agtatttttc tagtattata gcacatttaa
    21601 agaaggctgt gccgttttta ctgcgatttt tcctgaaatg tcaataatta gaggtgaatt
    21661 gtcctattgt cgtccaatct cttgctaaaa taactcttta taaaaggcaa tcgtttcttc
    21721 taaggttggc ataaatggat ttcctggtgc gcaggcatca atcaaggcat tcttagaaag
    21781 gtattcaaag tcgaaatctt tttcttcaat accaagttca gtcagtttct taggaatacc
    21841 tactgtctca gaaagcttct caatctcaac aatcgcataa tcggcacatt cttgatctga
    21901 tttaccttct acatgaagtc ccaaggcttt ggcaacattg cggaaagctt ctggtacacg
    21961 tttagcattt tcacgttcta taactggtag caacatggca cagcaaacac catgtggcaa
    22021 attatatact gcaccgagtt ggtgagccat tgagtgaaca taaccaagac cagcattatt
    22081 aaagctcata ccaccaagga agatggcatt gaccatacct tcacgcgctt caatatcatg
    22141 tccattttct acagcacgag gaagatattc cttgataagc tcaatagcac caatagacag
    22201 tttcttggtt acatcataag caccaggtgt taccaaagct tcaacagcgt gagtcagagc
    22261 atccatacca gtagcagcag tcaggccttt aggtttggaa agcatgagtt ccgggtcatt
    22321 aacagagata agagcaaggc tattcttgtc aaccattacc atcttaacct tgcgttcttc
    22381 atcagtaatc acatagttaa tagtgatttc tgcagaagtt cctgccgttg tattgatagc
    22441 cacaactggc aagccttttt tagcagactt atgaagccct tcataatcct gtggttttcc
    22501 accatttgta gccatgatag aaatacaact agctgcatcc tgtggagaac ccccgccaag
    22561 actgatgata aagtcacagc catgttcttg caaagcagct accccatctg tgacattttt
    22621 acaagtaggg tttggctcta catcgctaaa gatgacatat tcgattcctt ctgtatccag
    22681 tggttttaaa accttaggta aaatgtcact gccttcgatg tacttatctg tcaccaaaag
    22741 tgccttttta tagccaagtt ccttgatata aggacccact tcatttacaa cacctttacc
    22801 aataaggttg actgccggaa cataaaatgt agccatataa ttttcctcct gcgcctccgc
    22861 gctatctatt taacatcatt atattagttt ttgtattcgt tttcaattat ttgtgaattg
    22921 tttaacaaat ctttttaaaa ggataggagg gacataagtt cacctcctat atacacaatt
    22981 tttatttatg tagcggtccc aacaactgac atgcacgata gtctgctgat tctagatctt
    23041 ctgttccaaa taaggaccaa tttttaggtc taaagatatc ttcctcgggt acattatgca
    23101 tattgacagg aattctcaac atagaagcca aggtaatcaa gtctgctcca atgtgtccat
    23161 atgttatggc tccgtgatta gctccccaat tattcatgac gtcatagaca gacttgaaag
    23221 caccttttcc tgtcaaacgt ggagcaaacc aagtagttgg ccatcctgga tctgtacgat
    23281 tatctaaagt atggtgaaca tcttcaggaa gttcaagtgt ataaccttct gcaatttgta
    23341 gcactggacc aacccctttt agaagattga gacgtaccat tgttactggc atatccccct
    23401 tcgtcaagaa acgagttgag aatcctcctc cacggaagta ttcgcggttt gctggtggga
    23461 agtctgtatt ttcaagcata gcctgcactt cactttcttc caactcccag aatggtttca
    23521 taacaggttt gccatctcga gtagcttgac ctgtaccatc caatgtacaa gaaccagagt
    23581 tgattagatg taagaagcca gctgcagcac gaccctctaa agtatgtccc gttacacgtt
    23641 taacagcctc tggactccaa taagtacgca catcagcaaa tatttgtgga gtatttgtta
    23701 atagataatt aaagagcata gacacaccat ttagtgaatc attctctgtc gcaaatacaa
    23761 atggttttcg aataccattc cagtcaaact gagtattgag gaaagtttcc ataaaatctc
    23821 catttggaaa atggtctgtc cactgacgtt gaccttggaa accagctact aaagcatggt
    23881 gaccaactgc ttcttcctca aaaccaagtt cagcaagtct tgggttacca accattaagt
    23941 cacgtccaat catgaacatc ttaataacaa attcccattg tctatctttt tcttcacggc
    24001 ttaaaacaag gtcttcacgg ttatggtcga atccttcttt tacgttttct ttcacccatt
    24061 tgagcgcacg ttcaaactct tctgggtcat aaataccacg gtccatacgg cgcgtgaact
    24121 ccgtcatatc taccgattca tttcgcattc ctaagtattc ttggaagaaa tctggattta
    24181 caatagaacc gccaatcccc atcgaaacac tacccattga taggtaagca gtgtctctca
    24241 tcaagccagt tgcaagagct gcacgcgcat aacgtaaaag tttttctttg acatcttctg
    24301 gaatatctgt atcattagct tcctgaacat ctctaccata aatcccaaag gctggaatcc
    24361 ctttttgagc atgtgaagct agtacagctg caagatagac agctcctggg cgttctgtcc
    24421 cattaaatcc ccaaatagca tgaggaatat ctggagacat atccatagtt tcactaccat
    24481 aacaccagca tggtgtaact gtaattgttg cgcaaacatt tgattttttg aacaactcat
    24541 gggaagctgc agcctctgga acacgaccaa tggtagatgg agaaatcaca cattccacag
    24601 gttccccatc tggatatttc aatgtgcttg aaatcaaatc tgccacactt ttagccatgt
    24661 tcattgtttg tacttcaagt gattcgcgta caccttgacg acgaccatca atagtcggac
    24721 gaatcccaat acgtggatgt tgaatcatac tattttcctc ttatttttct gtttctttca
    24781 tactaccgat gataattttt aaaattactt ataagtataa acctctacct ctgccaaact
    24841 taaaggaatt cctgcgtttc tcaaagaaat tctaaccttt tttcccttca gcccttttaa
    24901 gtctatggat agattattgc tttctaaact gtcaatatgt tgtttaaaaa cttcatgatt
    24961 atttgaatca tatataataa tatcaaaatt tgataatctc tgaatttcag catctgttct
    25021 attataaata attaactttt ctaattcttc ggtttgtgct aaatctatct cccaccatga
    25081 aggagaatct cctttggtat gagtcactga atgatgacca taatctccgt ttttatttcc
    25141 atcaactgct agacgagaaa aaccattgta atccgttgaa ctctgtcgag tttctttggt
    25201 taatgcaata ttagaaagtt tcttcggagt tctctttgaa ccatagactt caacttccgc
    25261 taaacttaac ggaatagctg ctgattttaa ttctattttg actagcttag cccctacaga
    25321 aggtactttt aaagataaca aaccatcaac tactttatca aaatgtcttc taaaaacttc
    25381 ttctcctgat gaagatagaa aaataacatc aaaattagat aaacgctgag gttcggcatc
    25441 tgttctatta taaatatcaa ctttagaaac cgtaaactct tctcccagat cgacctgcca
    25501 ccaagcgtta gaatctgcct tagtatgagt caccgaatga tgtccgtaat ctccatcttt
    25561 attaccatca actgctaaag cagctacacc ctcataattg gttgaacttt gagtagctac
    25621 cttatttgta gagactactt tatcttctgt tattttatct atatcctctt cagattgctt
    25681 accatctgat tctctaaaaa cctctacttc tgctaaactc aaaggcactc cactcgttag
    25741 taatttaact ttaatatacc ttgctccttt ttctttgaaa tctagactaa cagattcacc
    25801 cgacaaatta ttaacatgtt tcttagcaac ttcgtttcta ttattgtcat atagaatcac
    25861 atcaaaatta gatagacgtt gagtctcagc atctgtgcga ttataaattt taacaagccc
    25921 aactttatcc atttttttca aatcgacttc ccaccaagaa ggattatctg ccctagtgtg
    25981 tgttaccgaa ccagagttaa aattaccatt tctgttacca tccacagctc tattagggtc
    26041 tccattgtaa tctacagaac tttgtgttgt tggttttgca tatgctatat tcaaattacc
    26101 atcattaaat ttatctggtg ttgggaaagg gactgggcct gtcccttcag tatttataga
    26161 catctctacc attccattat gattaaccgt aatggtataa acatgggtat tctcatccca
    26221 attttctgta taagtataat gatttttatc gccacttata tttatctgag gtttatgacc
    26281 agtatgccct tttaatgtaa gtgttgttgt cctaaagtca ttatctacag gattgatgga
    26341 ataatttttg cttatccagt tcgctaactc taattcttct ttcttccaac tttttgatgc
    26401 atcaaaattt cctgataatg cccacatagc tgtcttatct gtcctgtaat tgttcaataa
    26461 aatatgtaaa ttatttggat tttctttaac aacagcgtaa gtatgtggcg tcaaatctaa
    26521 cgataacgac tttgtattat tagtatacat aggcaacatt acttgctgat ttttattgat
    26581 attagcatta ctattataaa tataccagga attacctaca cgctgagcat acccatctcc
    26641 ttcataaagt tttggataaa gcgagtttaa atagttgact ttactagaca attcctcact
    26701 atttttagtc aaaatttttg cattagggaa tatagatgaa atcttttcct tatcaatttt
    26761 ctcatgtatt acaggaagaa tatgatatct cccattatta tataaaggca ttgtttcatc
    26821 attcgaataa agtccttgat aaaatccgtt taatgaacta atcctacctt ctccattcca
    26881 aaatacagct tttgttctat ttacaacttc ttccttactt ggagctggat tttgtatagc
    26941 atgtctaaag aaaggaataa tacctttagt aaatgctgga gttggtacat catttgtcat
    27001 aaatgtatac gcggcacatt cgaaattata aactgtgcct cccccagtat atacattcat
    27061 catttccata gcaatcattg attctggttc cgatgcatag gatctcatat ccctagctct
    27121 tccagtttca aatgtgtttg tataatgttt ttcccaccat ttccatgtat ctgttgatga
    27181 gccccagtta tcacataagc cactcaacca aaatccacta acgatagaat ctgtacccgc
    27241 atcatctctt attggcgtat ttttagttgc caacaccaaa tttttatgat atttttgact
    27301 cgcttcaaag aatgtcggat cattcataat agtttcccag aaccattttt catgatcatg
    27361 ccagataaaa tgcgctccat atttggcaca aacttccaaa tatttagcac tatgcggagc
    27421 taactggtta ttgtaaatcc aataattctc aatatttaaa acacctttta acacactata
    27481 cttttggaat tgttcatcta accactctgg aggaactgta ttacgctctc cagccgacat
    27541 aataaccaag aaaactggaa tgtttagact ttgagcttcc tccaacatct tgacatacca
    27601 ttctctcaat tctttcgtat ctcgtggaat acaacttgtt ggtttacaga cttttgcagg
    27661 atgaagttca atcgctgcat atggttttac atcttcagga atagcttccc atgctccctt
    27721 caatgtgttc ccccaccata atccgttacc attatcattg ccatacaacg gagaaagcaa
    27781 caatggcgat tcattattaa tcgtcgttct catttgaaca cgattatcag ccttaactcc
    27841 tgctaacaat ccaaaacata acatcccaat acatacaaac agtattgtga ttaattttct
    27901 ttttattttt tctttattca tgacttatac ctaaaaattt aactcaataa ttttttctga
    27961 attaaatacc aattcaatat tttgtacatc agtatttttg ccatatattc ttactcttac
    28021 tttttgatct ttgtttcctc cttccaattt taggaatgtt atatccccat ttttccaagc
    28081 aaacgatacc ttatatcctc ctcttactct gaaacctttc acttctcctt ctgaccaagc
    28141 agaaggtaaa gctggaatta gtgataacca attatgatgg ctctgtacta ataattcaca
    28201 aattccactc accaaaccta aattaccatc aatttgaaat ggtggatggt caagaaataa
    28261 attgccaaga gtcgcattat ttaacaaacc attaatctgg ttataagcag gttcaccttg
    28321 atatagtctc gcaaaaaaat gaatcagcca tgcagcactc caacctgttt gtgtactagc
    28381 atgcaaacca cttactaacc aattattaat cgcttgctcc ctctcctgtg aagataaaaa
    28441 gttagcgttt gataatctcc tattgatagt gattttagct gcttctgcta attccggagt
    28501 tttatgaata tcaatctcat tataaggata aagcccaaat agaggtgaaa tgtgtctatg
    28561 cccaggctct acttcttcat aatcttctaa ccattcttgg atttgcccat tactacctat
    28621 ttttgtttta ggtagtttct tttttaactc cttcacacga ctaataaaat ccgaattgtc
    28681 tcctaattgt tttgcaatgc caatgcatga atcacaaaaa tatcttagaa tttgattatc
    28741 aattgtagat gatagacaag catttccttc aataccattt tttaagcgat atttattttc
    28801 cggtgagaca cttggacctg tcatcaagta gccatccacc tcaaataaat aatcttcaaa
    28861 gaaaagaaat gcttctttta tcatttcaaa atgttccgta agaatacgct catcttggaa
    28921 atataaatag tgttcccaaa tatgagtaca taaccatgga atagttaata cccaaattgc
    28981 agcccccatg gcatgagatt ggggagccgt atcgccaaaa ccatccgtat tatgatgtgc
    29041 tgtaaaacct ctagctccat acattttctt agcggttagt cttcccggtt ctctcattct
    29101 ttcgagcata tcaaataatg gatattctac ttctggtaaa tcacatggac ctaccatcca
    29161 ataattcatt tgagtattaa tattaatcgt atatttagaa ccccaaattg gatttaattc
    29221 atcacaccat attccttgaa gattggcagg taaaccattc ggttgactag acgatattaa
    29281 cagatatctt ccataatgaa ataacaagtt agtcaagtag ttactatact ttttagtgtt
    29341 ttcaagaagt agattcgttg gaatgctaag acaatcttta ctatagtcta gtttaaaatc
    29401 aactctatta aattgctcct gatatttttt tacatgttca tctttttctg taaagtaatc
    29461 aatactacta aattctccct gaagagaaga aatatctata tttccccaat aatccgtcat
    29521 tgatttgaga taaagaaata cctctgtagc attccgaata actattgtct ctcccaatac
    29581 acttacttca ccatccgtaa ccttagaatg acatactact ttaaactgaa caccttttct
    29641 acctccagca gaggccgaca ttaaaattgt acttgaatcc agtttagata cttcgtcatt
    29701 aaaccgttta tttctaccca aattaatgtt taaatttaat gtgttttgaa ctgatgacac
    29761 tatacggcaa cataaaatat tcttattaaa actcgtaaaa tattctcttt ttatttgtaa
    29821 attacaacta ttaggctcaa acacaacatt agaaatagct gtatctaaat ctagctctct
    29881 ttcatacaat gaaagagcac aagactgaat atctatatgc tcaatgtaaa gttccccaag
    29941 taattcatag tggctttgat ctcttggggt agcaaacatt gttaacttta tcaattcttc
    30001 ggctttctga atttctccat ctaaaagata ttcccgaatt tttttaagat gcaatagtga
    30061 gtctggatta tttctatctg actttcctct ataccaaata gtctcatcgt ttagttgaat
    30121 acattctttt gtagctgaac cataaatcat accacctaaa tgaccgttcc caatcggcaa
    30181 ggcttcattc caatttgagg cagctttctt ataccataat ttcactcttt acctctcttc
    30241 caaaatggag gtgatatccc aaataccacc tccacacttt ctactacttc aaaattccta
    30301 aaacaactag gataactcca atagccataa cactaaagat tagtacaacc ggattctttc
    30361 cttttctaat taatttacac attaataaag tcaaagccat agggataaat cctggaatta
    30421 attttgtaat catttcttga acagaaataa caagttcccc ctgcttaaat tctaatccaa
    30481 aattaatacc aaccattgat ggaatcaaac cacccactag tactagccct aatgctgtcg
    30541 ccatactcgt aacgcgattc aatgttcctt ttgtattatt ttcttggata agactagaac
    30601 ccttagtata cccatatttc aaaccgaaat atttaacagg aatattaata atattaaaca
    30661 atattaaggc gataaagata cctaaagcac cgccgtcttt agaataagac gcaccaatac
    30721 taaaacagat aggaactagt gtcagccaga acaaactatc tcctagacca gccagtggcc
    30781 ccatcaagcc aactttaata ccagtaattg aagctgcacc ttcatttcct tcttgttctt
    30841 ccatagcgga agtaactcca agaataaatg gtgccgctgt ttgatgagta ttgaaaaact
    30901 caaggtgacg tttcattgca ggagaagctg aatctttgtc tgggtatagt tttttcaata
    30961 ctggaagaat tgtatataga aaacctaggt tctgcattct ctcatagttc catgaagaac
    31021 catacataaa acttcgtttg aaaacttttt taagttcaac tttagttact ttattattca
    31081 tcatagatca agatcctcct caacatcact acttgaagtt gtttcttgtg gtttacttcc
    31141 aatcatatcg tagaagtatg ctaccgcaat accaactagt gagatcccaa tggttgacat
    31201 tcctccatac acagaacaaa tgaatccaat caacaagaat acccacatat ttttcttgag
    31261 catcatattt aaaagcatac caaaaccaat tgaaggtagt aaagcacctg cagagttaag
    31321 tccctgcata acgattggtg gaaccttagc aaacaagtct gccacatatt cccctccaag
    31381 cataatagct aggaaaattg gtacaatttt aaataacgtg attaaaacca aacttgaata
    31441 atgataaaaa ccgatctttg aataatctcc gtttttagca tcattatcag cttttttcac
    31501 aaaataaaca tctaaagttt ttgcaagaac atccaactgt tgggtagcaa ctgcaattgg
    31561 aactgctata gcgataccag cagtttctcc ttgaccagat aaaataccaa atgcagtacc
    31621 aataatcgca cctgaaatag tatctggtgg agtgtaacct ccaatacctg ttacaccgag
    31681 ccaagttaat tcaagagctg aaccaataag aacaccttgg gtgaaatctc ctaagactaa
    31741 gccaaccatt gcacttgtaa ctaacggacg gtgaatcata aataacggtc cattatagtc
    31801 aatagtggca ataatcccaa ctaatgtcac cagtaatgct tgtgtgaata gcatatactg
    31861 tacctcctta aattattttt ataaaaattt ttccaacatt gtaactttat cattaggaac
    31921 catttgaatt tcaactctcg ttcccttatc aactattttc ttaaaataat atttgtcttc
    31981 ttcacctaga gctacacctc ccgttacctt ttcattttcc tccgttttac tcatctgtcc
    32041 tacattgagg tactccaatt ttaaatttcc ttcaatagaa tcatacacat cttttggatt
    32101 tgtatatatc agcattgttc tcttttttat tggcacagag tttaaaactt ccacaaaccg
    32161 ttttacacta aagaaaacaa tttttaaacc tactggtgca gaaatcttta aaatagattg
    32221 tcgtgtttta tcttctgaga tgcgatcatt aacaatgata acttgctcaa tatcatactt
    32281 ttttagccac gtagtgacaa cttgaccatg taccagacgg tcatcaatac gaacaaactc
    32341 tatagacata aatcttcttc ctcctctacg ttaagttgtt gtttaacatt aaacaaacta
    32401 ttttgagcat tgtgaacaat ttcttctaaa ttgatttttg aatcataatt tgatattaat
    32461 tccactagga gaggaatatt aaaccctgtt acaatatcaa ctgaatccaa atttaaaaac
    32521 cgtgacaaag ccacattatt aggacttcct ccaatcaagt cagtcaaaac gataacctct
    32581 tgatttgagt ctaacagttc atccacttga tttttaaaat aatgctcaaa ctctacaata
    32641 ttctctccag gcatcaaacc taatgtccta actctatcat ttgttgtctc accaacaaac
    32701 atttctgcgg tcatgagagc tccgctagca aaatcaccat gactggcaac taaaattcct
    32761 ctattaaaca ttttctcttt caacaactac tcctttctta aggataatat tagcataaag
    32821 tgaagtttct cctgtagcaa caatagcata agctttctta ctacgttcat aaaaatcttc
    32881 tcttctaaga taagtaatcg ttttaagatc tgtaccatga ccttcaatca tctgtctata
    32941 ggtaccccat atcttaggaa tatcatcacc cgaaacaacg ttcataaact gaattgaact
    33001 atcgacgtaa ctatctaatg gcattaaata cagaatggaa tctaataatt ctggaatatt
    33061 tacgccatca caacgaatta gcttatttgc acatgaggca gaaggataat tcgcgtcagc
    33121 taatactatt tcatctccat gtcccatttc cattaaagtc ttcaataaat ctggagaaat
    33181 atttttcggt atatgtttta acattaatat cctccctatt ttctctgacc gtatgtttta
    33241 aatttttctg ccatcaattc catctcctca tcaggaagaa ctactggctc tccaaaattc
    33301 ttagctaaac aataaatttt tgcacaatat tcaacttctt caacaatatt aaatgcattc
    33361 aataaatttt gtgcacctgc taaaattcca tgattcgcta gtaaaactgc tctacgacct
    33421 tccattgctt tagctgcatt cacagccaat tctttcgtgc catatgttgc atactcagct
    33481 acccgaacat ctttccctgc cactgcaatc atataatgac tcgctggaag tggttctctg
    33541 agacaagcta atactgttgc ataagttgta tgagcatgga taattgcatc gatatcatca
    33601 cgagtttgat attgaatcaa atgcatatac cattcgctag atggcaagcg ttctccctct
    33661 acaacatttc cattaatatc catcactaca atatcggatt ctttgatttc aaagaaatca
    33721 atacccgacg gggtaattgc catcaattgt ttttcacgat cgaaaacgct gagattccca
    33781 cctgttcctt tcgtcaaatc tgtttctact agcttcttac catatttaat taattcttgt
    33841 tttacatctg acatccttgt cctcctcata tcaaaacact aaatattttt caattcacca
    33901 attatccccc cttcctgcac aaaagctaag aagggggagg gaggcaaatt tacaaactct
    33961 caatcttttt aattcttttg ggagtaataa ctctctaatt gtagaaactc ctcaataaca
    34021 tggtgagcct cttccatccc ttttaattgt cccatagcta tgagctgcac aacaatattc
    34081 cccacagctg tagcctcagt caaacctgta agaacctctt taccagttct atcagcaatc
    34141 atttggttaa agtaactggc tctagcacct cctccaatca catatatcct cttataaacc
    34201 ttatgagtta gttcttctag taactctatc gctttcctat acgtttcagc taggctttca
    34261 taaacaatct taaatagttg tccatctgtc cactctctag tttcatgatg ataagctaga
    34321 tattctgtca aagtcttgtg catatcagat tctgttgcaa attcagttga ttcagtatca
    34381 atcagaggaa gattttcttt ttctttctcc accattgtcc taatatcatc aaaagaatag
    34441 gctttccctc ttcgttcaaa tgaacgtctt agttcctcta tgatccacaa ccctgtacaa
    34501 ttcttcagaa atgtaatcac tccatcttta ccgacttcat ttgtaaatcc ataactgaag
    34561 gattcggtag taagaatcgg tgaagtaagt tccactccaa ccaaagacca agtacctgat
    34621 gaaataaata aactaccttc tgtcttaggt actgagacaa tcgcacttgc tgtatcatga
    34681 ctacaaacat tcacaacagg aatatcgcct aaaccatact ccttttttat ccttccaaga
    34741 acatttccct ctgaaacaat ttcaggaagt aaagatgaat ccaattcaaa tagttttaag
    34801 atattctgat tccaattttg actcctagga tcaaataatt gagttgttga agcaatgctt
    34861 ttttctgtag caaacttacc tgtcaagaga taattaaaca aatctggcat taaaagaatc
    34921 ttattggtct tatagaaaga gtcaggagat tcttgacgtg ccttaaagag ttgaaacaag
    34981 gtatttatct ccataatctg atttcctgtc tctgaataca gtttttctaa ttcagtcatt
    35041 tcagatattt cctttaacac tccctttgtt ctttcatcac gataatgaac aggttgtgat
    35101 aacagcttac cttcattatc aatcagtcca aaatcaactc cccatgtgtc aataccgata
    35161 gataaaatct tgtaactagt attagccaag cggatacttt caagaatttt agctagtaga
    35221 aagtcaatat cccaagataa atgccctttt actctaatag gtagattaga aaagcgattt
    35281 atttcttcca ttactagttt attttcagaa aggtaaccaa cgattgctct tccagaagtc
    35341 gcacctaaat ctattgctaa aaccgcttcc atttttcttc tctcttcgtc cttgattaac
    35401 tttattataa tccccacgtt ttattttttc aatatattaa cgcttacttg aataatgttc
    35461 aaatattaac ccaatattca taaaaataat tcaaattcct ccaatttgtg ctataatata
    35521 gttgaaatga taaattagga ggagcttatg ataaaagatg aacgtgtact tgaattgatt
    35581 gaaattatta aaaagaaaaa aagaattgcc gtaaaagagc tggcagaaat cactttctcc
    35641 agcacaagta ccttacgtcg tgatttaatt ttcttagaaa atcaaggtct tatcaaaaga
    35701 aagcacggat acgtgaccct gtcctctatg aacacaattg aactttctca tcaaatacgt
    35761 gaaggagaaa gtactaggca aaaaagacta atcgctagtc tcgctaaaga ctttattcgg
    35821 tctggtatgt gtatctatct ggattccagt acgactgtct acgaactttg tccctatctt
    35881 tctgaacttg ataatttgat tatttttaca aatggtttac atactgcaca aaccctatct
    35941 gaaactgtta aagatagctc caaaatcttt atcacatctg gcgaggtcaa acatcaatcc
    36001 tgttccgtgg tcaactatga taaggaaaat tctttattag atcattttaa tatcgattta
    36061 gcattttgtt cagcaagagg tattgatgac caatatgttt atgaagcttc tctcagccaa
    36121 gctatttcaa aaaagaatat tattgacaaa gcccatgaaa ccatcttact gattgatagt
    36181 tctaaatttt acaagactgg attttttaaa attaatcccc tctccaaata cacaaccttt
    36241 atttcagaca ccgtgccaga tcaaaaatta ttagacgcag tcgaattatt tgatggagaa
    36301 tgggtttctg atattcaatg aaaatcaaat aggaagctag tctcagcttg ctcaaagtac
    36361 agatttgaaa attgatcaag tcagctcgaa acactgtttt gaggttgtag atagaactga
    36421 tgaagtcaag tcccccatgg acacggcaag acgaagctga catgatgtga agagattttc
    36481 gaagagtatt cgttctgtct gctgactgat ttacaaatat tcaccacatg acattatttt
    36541 cttagcaacc ccaaaaacag aggctggaca aaaactcaat ttcaggagaa aatggagtaa
    36601 accttcccac aataaaacgc atagtatcaa gtttttgcac acctgatatt atgcgttttt
    36661 ctgattttaa agactttgtc gcctagaccc tatatttcaa gaattaagtg accttgatga
    36721 tctaaattta ttgtggtata ctatttttgt catcggttac cgattacgtt cctatgggtt
    36781 cgtgagagaa ggtgaaacta atgagcctta tcatagagct cgctcttact attatagcgg
    36841 atgttatagc tggaattatc ttgtatttcg tctgcagatg gctagatagt aaggagtaga
    36901 ccgactgact agcctataaa cacccgttaa atcgctaaga tacgtcaaaa aagcccttaa
    36961 ctatggcact agttaggggc tttggtgttc taatgaacct tatacactaa ctacattcta
    37021 gcatataagc ccagatattt caagagtttt atttattgtt taaagttctg aaaggtctat
    37081 aatgaagtta gccatctagt atcaaaaaac cgactagctc ttatgaacta gtcgatttct
    37141 catcaatgcg ccaacatttc ttgggcgatt tcttggccag ataggttatc tgggtagtag
    37201 gttggccagt tgtccatttc ttcaaagagg gcttcttggc ttgtgcctcc aaagaagata
    37261 tggaaatgtt ctgccttaac tggggcaaca ttgtggtcac taaactgaac atacttgaat
    37321 tgtccagcgt cagcatctgt ggcttcaaag aggaaacgca cgccacgatt gcctttcttg
    37381 taagtcaaaa ttttcttacc gacatacttg taagtgtatt tcttgctttg tccaccttga
    37441 acaaattcca tagtattatc agtaatgtta atcttagtca catctgtctg atagcctttt
    37501 gtatagtaag ccttgtactc agcctgggtc atcttaccag tcaacttagc cttgtagtca
    37561 aagacttggt caaacgtgcc gtcttcaagg aaaggataaa ctgattgcca gttacctgca
    37621 tagtcactca aggtgcggtc cttgacagct gcatcctcga agtaaccatt tgggactgtc
    37681 ttggtatcct ctgccttttc aggttcgatt gctgggcctt cttggtctgt tgtttgtttc
    37741 aaagccttga ggtttttctc catcacggaa atgtagtttt ctccagcctt ggtgtcctct
    37801 tctgtcagac tttctaaagg attgaggaca tcagttttga cacctgcttc ttttgaaagt
    37861 gtgttagcaa gggcttgtga ggcattttct tcaaaataga tataggcgat tttatttttc
    37921 ttgacatact ctgtcaattc tgccaagcga gcagctgatg gctctgcatc tggagaaagt
    37981 cctgagattg cgacttgttt gagtccatag tccaaggcaa gatagttaaa ggctgcgtgt
    38041 tgagtcacaa agctcttttg ttttgcttga gacaagcctt ctgcgtaagc cttatccaag
    38101 gcttgcaatt tttcgatata ggcagctgca ttcttctcaa aggtctcttt tttatcagga
    38161 taatctgctg acaagctgtc gcggatgtgc tctactagtt taatggcacg aactggtgat
    38221 aaccaaacat gggggtcaaa ctcatggtga tgaccttctt ctccatggtc atggtctccc
    38281 tcttcttcct cgccacctgg caagagcaac atatcgcctg tcgccttgat ggttttcact
    38341 tttttcttat ccaaggtatc tagcaattta ggtacccatg tttccatgtt ttcattttca
    38401 taaacgaagg tatctgcatc ttggattttg gcaactgcct tggcagatgg ttcgtattca
    38461 tgaggttctg tcccagcacc gattaggagt tctacattag ccgtatctcc tgcgacttgc
    38521 ttggtaaatt catagacagg gtaaaaggtt gtcacgatat tgagtttacc atctgcctgt
    38581 ttttgattgg aacaagccac taaaaacaag gcacatagac tggctagtaa taagctaatt
    38641 tttttcacgt tcgtctccta tttgataaaa cgtcttacta aactgattag tataaagaca
    38701 gttacaaaaa taatggtaat acttgcactt gcaggtgttt ctgcatagta ggaaatgtaa
    38761 agtcctgcta ccattcccaa aaagccaatc gcactggcaa gcagcataac cgatttaaag
    38821 tttttcccca gacgcagggc aatactagct ggcaagacca taatggtcga taccagaaga
    38881 gctcctgctg caggaatcat aagggcaata gccacccctg tcaccatgtt aaaaagaatg
    38941 gacatggtac gaactggcaa gccatccaca aaggccgtat cttcatcaaa agttaagata
    39001 tacataggac gaagaaagag aaaggtcaaa atcaaaacaa ccgccgcaat gacaaagagg
    39061 gaaatgacct gttcttcact gatagtcacg atcgaaccaa agagatattg gtccaaactc
    39121 attgaactcg agcttctacc cttgctcatg acaatcagag aaacagccaa acctgttgac
    39181 atgaggatag ctgtcccgat ttccataaag ctcttgtaaa ccgtacggag atactccaga
    39241 aagaccgccg caatcaagac aatggcaata gtagaaacag ttggagaaat ccccaaaacc
    39301 agaccaaagg ctacacctga aagtgagacg tggctaaggg tatcactcat caaactctga
    39361 cgacgcaaga tgaggaaggt tcccaatacc ggtgagaaaa gactcatagc aataaccgcc
    39421 aaaaaggcgc gttgtataaa gtcataagat aataaactaa gcatggccca cctcctggcc
    39481 attctcatga acgttgaaac aacgccatgg cgagtcttgg ttacggacta gatgaatatt
    39541 gcgatccgca taatccttaa cttcttcagg gtcatgggta atcatcaaaa cagccttgcc
    39601 atgatgatgg gcgctgtggt gcatgagttc gtaaaattca tttttacttc ctgcatccat
    39661 ccccgttgtc ggctcgtcta ggataaacac atcagggtca gaagcaaaca tacgcgcaat
    39721 caccgctcgc tgcttttgtc ccccagatag agaccccaag cgtttgtctc gatgttccca
    39781 catgccaact gagtccagac tagccttgat atgctcctca tcatgagcat tcaaacgacg
    39841 gaaccagcct tttctcggat agcgacccga cttgacaaat tcatagaccg tacttggaaa
    39901 accagcatta aaactggcaa tttgttgagg aagataggct attctcaatt tcttaccttg
    39961 cgtatttgtc tttgaaatag ccacctttcc aatgcgtggt tgcagaattc caagactagc
    40021 cttgatgagc gtcgtcttag ccgctccatt ttccccagtc aaggtaacaa attccccact
    40081 atcaacacta taattgatat gttcaagaac aggctcctta tcataataga aggacaaatc
    40141 ctctaccgta atatatctca ttatttgatt tctcctacta aagcagtcaa aaaccgctga
    40201 atcacttttt gttcatttgg agtaaactga gtcgccactt gttcataggt taaaagtgta
    40261 tgctcatggt gatggtggtg ctcctcagcg attggacgag ccaagtcagt caactgataa
    40321 aaaatcacac gcgcatcttt agaatcttta gatgtttcca acatcccttc cttgaccaaa
    40381 gacttaatgg ccttggtaac tgccgcctga ctgacattga gacgacgagc caattctgaa
    40441 tttgttaaag attcctctga caagagcata aggatatgct cctgagtatt ggtcagggcc
    40501 acctcgctag tgcaatgacc tattaggatt tcatgctgat tttccgcctg caaaatcacc
    40561 tcattcaaaa aagcattgat atcctttgct agctgtctca tatctgactc ctttcctttt
    40621 agacttctct tttttaagag aaaaatacta ttctttgaca ttttgtttac cagttaatta
    40681 tatcacaagc aaaaaaagag tcaagaaaaa acgtgaaaac tagtttcatt cttgaactct
    40741 tctatattat attatctatt gaaattcttt gacatctcca tcataagtcg cccaatcttt
    40801 gctgaaaaag cgctcattca gatggtaagt cggagctggt gtgggattgg ataggaaagg
    40861 atcaactgcc ttgtcaaaag ccaaccaacc caaccaacca aggtgaatgg tgtccttcat
    40921 aaagaaaggc tccccgccgt ccttagaaaa atctgctata ttggtaaaac cttgactttc
    40981 taactggtag cgaatcttct gcaccgtttg ttggtacata tcctctcgta gaccagcata
    41041 gtccatccat tttttattaa caggtggaat gataaaaatc gggtttacct tagatttaga
    41101 aaactgtgtt aaaaccaact gcaagtcatt atactctggc gacttgagat aggtaaagct
    41161 tttctgagaa tcctttaatt tcttcaaatc cttcttgatc tgctcattat agaaataatt
    41221 ttccattccc atctcattat tggaagtatt tttttcagca tctgctttga caacatcttc
    41281 tattgcctga taagaaaact ggtctggcaa gatttttaaa tacttagcta catgcttatc
    41341 gtagttaaca tagcctctaa ccgaaaactg accaaaaaag gaagcttggc gttcattaaa
    41401 acgagccaat aattcaatca tttcattgtc tgctgtcgac aattcttctt tacttgccaa
    41461 cttctgaacc aggtccttca tagctacgtt tgggaactgt tgcagtaagc gagtcgctgc
    41521 atattgacta gcctgatccc cagattgatg tttcagaaaa ctagtcaact ggtctccatt
    41581 aaaatactgc tggaaggctg ctggatcata gccattttta ctgaaccact gaggtgagat
    41641 aacatacaca acttgtttat tctccagctg tggtaacatc tgttgcattc caaaatattg
    41701 gttaagcgat gcagctcccc cctgtcctaa aagataagga cggtaggaac gattgtattt
    41761 ctcagctaat accgcaggat gagcaccgtc aaaacgaagc cattcactag agccaaagaa
    41821 gggaacaaaa cgcacatttg gatcagatag tgctctgact ttttgacttc gctccttaaa
    41881 actatcgata gtagtagcca ctgctgaacg cttttcagct cctagattat gatgcatctc
    41941 agtaggataa aagaaaatga gcagaaaaac caacaaacca gcgatcaaga ccggtccgaa
    42001 gatcatccat aagcgtttaa gcattttgta gctccacaat accagctatg attttattag
    42061 ctgtattcca gtcgtcacga ccaaactctg ttacagggac acgaatgtca aaacggttct
    42121 caatctccac aatcaactca accgttccca tactatccaa gacacctgca tcaaaaagat
    42181 cttcatccat catgtcagaa acatcttcca taaacaactc atcaataatt tcaataactt
    42241 ctgatttgat atccatattt tatttccttt tattttttaa accatagatt attcaagaat
    42301 ccagaaaaga ttaagaatga caacatgaca acatggaaag tgacaaccat gccaagcaac
    42361 tgaatccagc gattctcagg tagggcagcc ttccctgctt ttttccgttc cttattgagc
    42421 gtttttttct tgcgaaccca ggcatcattg atgaccaagc ctagtccatg aaagagtcca
    42481 taggcgatat agtaccaggt cacaccatgc caaaatccca taatcagcat atttacaatg
    42541 taggccatgc ttgaggttac attacgattt ttaaagactt tctttctggt taacaccatc
    42601 accattcgca taaagacaaa gtcacggaac cagaaggaca gactcatatg ccagcgattc
    42661 caaaactcct ttaaatccct tgataaaaag ggcttgttaa agttgatagg gctacggatt
    42721 cccatcaagt ttgagatggc caaagcaaac atagaataac ctgcaaagtc aaagaagagt
    42781 tccagaccaa aagtatacat aactgccaag gcatagagat taaagaagcc acctgactgc
    42841 aaggctaaat tcttcagagg aggtagtaag gtctctccta aaacatgagc taggataaac
    42901 ttatacaaaa agccccgcat gatatagcgg acagattcat ccagcatatc catcaactca
    42961 tctcgctcag gaatggcctg ataattttca ttaaatcgct taaagcgatc gattggacca
    43021 ctcgagaaag ttggcatgaa gagaaggaaa cggaggaatt cccagagggt aaaatcctta
    43081 atcactccat ctctcagctc gatgataatc ccaaccgaac gaaaggtcag gtaagaaatt
    43141 cccaagaacc caagcaaaga ctgcgttcca ttgatagctg gttgcacctt gacaaagata
    43201 atcggaagta gggacagaaa actaactaag tagaagaccc acttgccatc cttgcttttt
    43261 cgataatgct tgtagaaaag caggagcaat atttcccagc aaaggtaaat acccaaggca
    43321 gctagttgat tggtctttcc acccaccaac atggtgacaa taaagaagag acttaccaac
    43381 acttcatacc aggcaaagcg tttcttgaaa aagagaccta taaagatggg caaggttgca
    43441 gcaatcacat aaacaaaata ctgaggattg ccatatggct ctaaatgagg aagctgttga
    43501 aaaaactcca tcatctctta ttcacctcgt taatcaatcc tttgatgtca atctttccat
    43561 ttggagttag tggcaaactg tctcggtaaa ggaatttaga tggcatcata taggacatca
    43621 tgatgtctgt caggtcttcc ttgatggcct tggtaatatc gatatctcgc tcaaactgct
    43681 cacgaacacc gtcttttaag atgacataag ccaatagatt ttgtaccttg tggtccttgt
    43741 tatagcgcgg tactgcgaca gcagattcga taaagcgaga cttgttgagg ttttgagaga
    43801 catcttctaa ctcaatgcgg taaccgttaa acttaatctg gaagtccatg cgtccgccgt
    43861 agagaagcaa gccctcatct gtcatggttc ccacatcgcc tgtgtgatag gctggcagac
    43921 cttcaaactc aaagaaggct tctgctgttt tttcaggatt tttcatataa ccttttgaaa
    43981 cagctggccc agaaacaatg atttctccct gctcaccatt tggcagttta tttccttcct
    44041 cgtcaatgat aaaggttgga gaatcagcct tggtatagcc gattggtagg cgtttgagag
    44101 tcgctaacat ctcgtctgtc acggcaactg ctgacagagc tactgtcgct tctgttgggc
    44161 cgtaagcatt gatgatacgg gcatttggga aacgctcgcg cagtttttga gctgttttga
    44221 ccgtcaattc ttcaccatca aagtagaaat gcgtgattcc aggcattttc tcactgttga
    44281 agtattcaga caacatggcc atatctgcaa aggatggtgt tgatgtccag atagcgattg
    44341 gcaatgaaaa gatagccgca aagagttgct taaagtcctg agtgatgact gaaggaagag
    44401 tgaaaagcgt accaccaagt gccaaggtcg gtgcccaata catgacagac aagtcaaaag
    44461 aataaggtgg ctgtgccagc atttgcggac gactcggtgt cgcaaattcc ttatccgtaa
    44521 tcatccagtt tgtaaagctg aggagattat catgtgaaat ctgcactccc ttaggcttac
    44581 cagtcgtacc agaagtaaag ataatgtagt aattatcatc tcccttgact ggatgcgtga
    44641 tttcatagtt gttcccttgg gcaaaggctt cttgaacctg agctagattt atcattggtg
    44701 tagaaacctg ctccaaggga aaggctgaaa tggcaataat caagcttggc tctgctactt
    44761 ctaaaatagc tgaaactcgc tccaaggccg aatggctatc aattggaatg taggcatgac
    44821 ctgacttagt cagcgctaca aaggttgcca acatttcata ttcttggcca ccaaaaacaa
    44881 ccacaggaga cttctcaggc aagcctagtt gggcaatgac tgcagccaaa ctatccgaat
    44941 cagcctttaa atcgccataa gtgtgttcct gccccaaaac attatagaca ggatagctag
    45001 gctgtgtctg agcaaaatgc tcaatggttt caatcatatc tgctattggt ttatttgaca
    45061 caatagggat tctccttcaa gttaaaattc attatagata aagcttcctt gaccctgacc
    45121 aagatagcta aagaagtaaa gcagccctag aaagataaga aaatacaagg ctgtccgacc
    45181 aagaaagagg tacaattctt ttctctgttt catcaagaaa aaccattcat ttctgtaatt
    45241 tttcgctaaa ataagagtga ttcttactag cttatttttc taccattgta ccactttata
    45301 tagtatcttt tcaattgttt accgtatgtt tccaatagat ttcagcttat tttaaggatt
    45361 atacagtttt tctatgtata ttttcaaata gagtgatcct gcttcaaaac tccatttcag
    45421 gagacaatga agtaaatctt ctcataataa aacacacaat atcaagtttt ttcaacacct
    45481 gatactatgc gcttttctga tttttaaaga ctttttaacc actctctcat ttaaaataat
    45541 ctcgtctgat ataaattaaa atagcttcta tcatcagaca aatggctgat agccaaaaac
    45601 tgatgctaat accaaaactc tcagtaatat agctcattag caaaacaaat actgaaaatg
    45661 ctaatgtaga aatcacttca agaacggaat agacattaac taaatgattt tcctctactg
    45721 tttcctgaag aaatacactt tcaggaactt cttttagttg cgataacata ccaactaaag
    45781 ctgaaaataa taaaaacatc tgtgcgtttg gaaaatatag aatagtcagt gtcactattg
    45841 ccatagctac aagaggaaaa agaatacttt cccatttagc agcaaggaac ttttcagata
    45901 gcctaaaagc aattaagcca ctaattataa taccaataga gtatgctgta ttagaatatc
    45961 cccagtaact ttccgtttta tttaataact ccgttacaaa aacaagtata atggaagaaa
    46021 cccaaatcgt atttgaaaaa atttccaata aatttgctga tacaaaagtc ttaatctagg
    46081 atttctagca actaacttcc aacctttgag caaaatttca agattagttt ctgactctaa
    46141 cacctccact tcagcgttag gaagaaataa catcagaaag ctagaaatga tatacaagac
    46201 taaaatgata aacgtggtag gtaacagacc aattgttgca aacaagagtc cacctaatcc
    46261 ccaacctatc aattgaacag cttcaccagt cattgataag gctgaattag ccttacccaa
    46321 atcggtcgca tagcgtggca caatagcata ggaaacgggt gctgcaaaac catctagtat
    46381 ggaaattgca acaacaaata gataggtcac caaaggcgct acggattgca ttacggtaaa
    46441 cattcctacc agtatcgcca ataatatagt ctttccaaat tgagataaag ataaaaccct
    46501 atttagcgct aaccttttag taaccaacgg aactaaaaga ctcgcaacaa aagaggatat
    46561 tcctattaag ataggaacta gtgatgtggc aattactgat tttgaaataa tgtatatgtt
    46621 agcaatgatt gttactctaa agaaaatatc tgctaaattt gcaaataatt gagagactaa
    46681 caacttgaca aatgaattag acatgtagcg ctcccccttt agttacaaac tttggaatta
    46741 aatttgattt ttaatatttt agcataaaat agcagaaaac aaaagtgagg ttttttacat
    46801 gaaaaaacaa aaactattgc ctttattatt cctaatttta ggaggaatta tgattatcgt
    46861 tgttggctag tactaagaag ttagttagta gaataattac atcttcaatc gaaaaagaga
    46921 ctggaaaaag tcttaaaaat cagaaaaacg ctcaaatcct ttggcgctct aagcttttct
    46981 aatgatagat ttagatagtc aaaaaaatat ctgaaaagtt cccaggatcg tcgtctcagc
    47041 atcaaaaata cgtgaaattt gcataattaa aataaatttc aggggagtta atcgagtagg
    47101 ggataatctc tagcccctct cacaccaccg tacgtgccgt tcggcataca gcggttcaac
    47161 taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt ccacgttttt
    47221 ccaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact aattgata
//
LOCUS       DBEROT010000013        43097 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.13, whole genome shotgun sequence.
ACCESSION   DBEROT010000013 DBEROT010000000
VERSION     DBEROT010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.13"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..1141)
                     /locus_tag="ACL8CG_000857"
                     /pseudo
     CDS             complement(1..1141)
                     /locus_tag="ACL8CG_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1335..1832
                     /locus_tag="ACL8CG_000858"
     CDS             1335..1832
                     /locus_tag="ACL8CG_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGS1343479.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            1832..3487
                     /gene="dnaX"
                     /locus_tag="ACL8CG_000859"
     CDS             1832..3487
                     /gene="dnaX"
                     /locus_tag="ACL8CG_000859"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGS1343480.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYTPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKSEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQIEKEVEESLIPEGFEFLADKVKVEED"
     gene            3515..3709
                     /locus_tag="ACL8CG_000860"
     CDS             3515..3709
                     /locus_tag="ACL8CG_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGS1343481.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            3859..4629
                     /gene="sufC"
                     /locus_tag="ACL8CG_000861"
     CDS             3859..4629
                     /gene="sufC"
                     /locus_tag="ACL8CG_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGS1343482.1"
                     /translation="MSVLEIKDLYVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            4657..5919
                     /gene="sufD"
                     /locus_tag="ACL8CG_000862"
     CDS             4657..5919
                     /gene="sufD"
                     /locus_tag="ACL8CG_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGS1343483.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLLGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            5930..7156
                     /locus_tag="ACL8CG_000863"
     CDS             5930..7156
                     /locus_tag="ACL8CG_000863"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGS1343484.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINACSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            7143..7583
                     /gene="sufU"
                     /locus_tag="ACL8CG_000864"
     CDS             7143..7583
                     /gene="sufU"
                     /locus_tag="ACL8CG_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGS1343485.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDVVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            7637..9049
                     /gene="sufB"
                     /locus_tag="ACL8CG_000865"
     CDS             7637..9049
                     /gene="sufB"
                     /locus_tag="ACL8CG_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGS1343486.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(9280..10521)
                     /gene="pbp3"
                     /locus_tag="ACL8CG_000866"
     CDS             complement(9280..10521)
                     /gene="pbp3"
                     /locus_tag="ACL8CG_000866"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGS1343487.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            10624..11733
                     /gene="cozE"
                     /locus_tag="ACL8CG_000867"
     CDS             10624..11733
                     /gene="cozE"
                     /locus_tag="ACL8CG_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGS1343488.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLIWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            12379..12726
                     /gene="ssrA"
                     /locus_tag="ACL8CG_000868"
     tmRNA           12379..12726
                     /gene="ssrA"
                     /locus_tag="ACL8CG_000868"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(12899..12986)
                     /locus_tag="ACL8CG_000869"
     tRNA            complement(12899..12986)
                     /locus_tag="ACL8CG_000869"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12950..12952),aa:Ser,seq:gga)
     gene            13149..13889
                     /locus_tag="ACL8CG_000870"
     CDS             13149..13889
                     /locus_tag="ACL8CG_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1343489.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            13886..14797
                     /gene="pfkB"
                     /locus_tag="ACL8CG_000871"
     CDS             13886..14797
                     /gene="pfkB"
                     /locus_tag="ACL8CG_000871"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGS1343490.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            14794..16746
                     /locus_tag="ACL8CG_000872"
     CDS             14794..16746
                     /locus_tag="ACL8CG_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS1343491.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            16883..19135
                     /locus_tag="ACL8CG_000873"
     CDS             16883..19135
                     /locus_tag="ACL8CG_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGS1343492.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(19180..19608)
                     /locus_tag="ACL8CG_000874"
     CDS             complement(19180..19608)
                     /locus_tag="ACL8CG_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGS1343493.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            19746..20888
                     /locus_tag="ACL8CG_000875"
     CDS             19746..20888
                     /locus_tag="ACL8CG_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS1343494.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            20897..22111
                     /gene="thiI"
                     /locus_tag="ACL8CG_000876"
     CDS             20897..22111
                     /gene="thiI"
                     /locus_tag="ACL8CG_000876"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGS1343495.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            22246..23070
                     /locus_tag="ACL8CG_000877"
     CDS             22246..23070
                     /locus_tag="ACL8CG_000877"
                     /inference="COORDINATES: protein motif:HMM:NF012958.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="HGS1343496.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            23083..24249
                     /locus_tag="ACL8CG_000878"
     CDS             23083..24249
                     /locus_tag="ACL8CG_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS1343497.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            24509..24634
                     /locus_tag="ACL8CG_000879"
     CDS             24509..24634
                     /locus_tag="ACL8CG_000879"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343498.1"
                     /translation="MKIKEQTRKLAAGFSKHCFEVVDRTDRVSIIYLRQGEADVV"
     gene            24757..26250
                     /locus_tag="ACL8CG_000880"
     CDS             24757..26250
                     /locus_tag="ACL8CG_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS1343499.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            26263..26805
                     /locus_tag="ACL8CG_000881"
     CDS             26263..26805
                     /locus_tag="ACL8CG_000881"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1343500.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRYSEEVVA"
     gene            26802..27920
                     /locus_tag="ACL8CG_000882"
     CDS             26802..27920
                     /locus_tag="ACL8CG_000882"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1343501.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGREIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLAL
                     QNEFADFVAQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            27980..28216
                     /locus_tag="ACL8CG_000883"
     CDS             27980..28216
                     /locus_tag="ACL8CG_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGS1343502.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            28213..28626
                     /locus_tag="ACL8CG_000884"
     CDS             28213..28626
                     /locus_tag="ACL8CG_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGS1343503.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            28744..29709
                     /gene="xerA"
                     /locus_tag="ACL8CG_000885"
     CDS             28744..29709
                     /gene="xerA"
                     /locus_tag="ACL8CG_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGS1343504.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            29732..30250
                     /locus_tag="ACL8CG_000886"
     CDS             29732..30250
                     /locus_tag="ACL8CG_000886"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1343505.1"
                     /translation="MFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIYGS
                     GGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYLFY
                     FCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVVQVDKSQFACEIAI
                     KVWRNSLKFSII"
     gene            30280..33630
                     /locus_tag="ACL8CG_000887"
     CDS             30280..33630
                     /locus_tag="ACL8CG_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS1343506.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(34136..34606)
                     /locus_tag="ACL8CG_000888"
     CDS             complement(34136..34606)
                     /locus_tag="ACL8CG_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1343507.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(34623..36896)
                     /locus_tag="ACL8CG_000889"
     CDS             complement(34623..36896)
                     /locus_tag="ACL8CG_000889"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGS1343508.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            37243..40344
                     /locus_tag="ACL8CG_000890"
     CDS             37243..40344
                     /locus_tag="ACL8CG_000890"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGS1343509.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGQSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            40426..41433
                     /gene="pfkA"
                     /locus_tag="ACL8CG_000891"
     CDS             40426..41433
                     /gene="pfkA"
                     /locus_tag="ACL8CG_000891"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGS1343510.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            41492..42997
                     /gene="pyk"
                     /locus_tag="ACL8CG_000892"
     CDS             41492..42997
                     /gene="pyk"
                     /locus_tag="ACL8CG_000892"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGS1343511.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT        13241 a         7597 c         9366 g        12893 t
ORIGIN      
        1 aatcttttcc ttatctttga agaaggtttt aaagacagtc tgaaaaatag gatgaacctg
       61 cttcagattg tcctcaataa gtccgaaaag tttctctggt tccttattct ggaagtgaaa
      121 aagcaagagc tgatagtggt gtttcaagtt ttgtgaatag ctcaaaagct tgtctaaaat
      181 ctctttattg gttaagtgca tacgaaaagt aggacgataa aatcgcttat cactcagttt
      241 acggctatcc tgttgaatga gtttccagta gcgcttgata gccttgtatt catgggattt
      301 tcgatccaat tgattcatga tttggacacg cacacgactc atagcacggc taagatgttg
      361 tacaatgtga aagcgatcca acacgatttt agcattcggg agtgaaacag tctgggagac
      421 tgtttcagcc tgagcctaga aatttgaaag cgaagctgtt tagccaagtc atagtaaggg
      481 ctaaacatat ccatagtaat gattttgacg cgacatcgga cggctctatc atatttaaga
      541 aagtgatctc ggatgatagc ttgtgttcta ccctcaagaa cagtgatgat attgagattg
      601 ttaaaatctt gcgcaatgaa gctcatctcc atctcccgat tgaaacagtc actccccgga
      661 ctgtttcaac gtcccaggac ataatctcag gaggacaaga aaaatcatgt ttaaagtgaa
      721 aatcattgag cttacgaata acagttgaag ttgagatgga aagctgatgg gcaatatcag
      781 tcatagaaat cttttcaatt aacttttgag caatcttttg gttgatgata cgagggattt
      841 ggtgattctt cttgacgata gaagtttcag cgaccatcat ttttgaacag tgatagcact
      901 tgaatcgacg ctttctaagg agaattctag taggcatacc agtcgtttca agataaggaa
      961 ttttagaagg tttttgaaag tcatatttct tcaattggtt tccgcactca gggcaagatg
     1021 gggcgtcgta gtccagtttg gcgatgattt ccttgtgtgt atccttattg atgatgtcta
     1081 aaatctggat attagggtct ttaatatcga gcagttttgt gataaaatgt aattgttcca
     1141 tatgattctt tctaatgagt tgttttgtcg cttttcatta taggtcatat gggacttttt
     1201 ttctacaata aaataggttc cataatatct atagtggatt tacccactac aaatattata
     1261 gagcccaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg ctcctttttt
     1321 gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag
     1381 aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc aacgccagtg
     1441 ctctcataaa atcacgtttt cctaataccg tatttgcagg cttttatttg ttcgatggaa
     1501 aggaattggt tttaggtccc ttccaaggag gtgtttcctg catccgtatt gcactaggca
     1561 agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga gatgtgacga
     1621 cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga
     1681 tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt gaggattacg
     1741 atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa aagacaacat
     1801 gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc gaaaatatag
     1861 aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc ttaaacaagc
     1921 ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa
     1981 aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag tgggtggcga
     2041 accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag aagatgtcat
     2101 tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc gtgataaatc
     2161 tacctatacg cctagccttg ctcgttataa ggtttatatc atagatgagg ttcacatgct
     2221 gtctacaggg gcttttaatg ccctcctaaa gacgctggaa gaaccaacac agaatgtagt
     2281 ctttattttg gccactactg aattgcacaa gattcctgct actattctat cccgtgtgca
     2341 acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc actatatctt
     2401 agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca gacgggcgga
     2461 aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga cacagggaaa
     2521 tgagctgacg actgctatct ctgaagaaat tactggcacc attagcctat cagccttgga
     2581 tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt gcttgaatct
     2641 tctttttgac aatggtaaga gcatgactcg ttttgtgacc gatcttttgc actatttaag
     2701 agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag tctttgtaga
     2761 aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa cagtgagttt
     2821 agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga ccgtccgttt
     2881 ggcggaaatc aagtccgaac cagctttatc aggagcggtt gaaaatgaaa ttgctacgct
     2941 gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gtaggtgcgg ttcctaaaca
     3001 agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa
     3061 taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac gtcaaaattt
     3121 aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc cggacaaggc
     3181 tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc ttgcttttga
     3241 gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca tgtttggtaa
     3301 tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca tggaggaatg
     3361 gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaattg aaaaagaagt
     3421 agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga aggtagagga
     3481 agactaaaga aagatttcat gatacaataa gtttatgaat aaacaacaat ttattattat
     3541 ggcgctgttt acagctgctg agacctattt tttcaatgaa gcctggatga ctggtcgcta
     3601 tattatggca gccttttggg caattttact ctttagaaat ttccgagtca gttatgtgat
     3661 gggcaaaatc gttgatgtca tcgatcagca ttttaatagg aaagactagc cctcagcttc
     3721 cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta tatttataga
     3781 atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt aaaagttttg
     3841 aaaaagaaag gaactatcat gtcagtatta gagatcaaag atctttacgt tgagattgaa
     3901 ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat tgccgctatc
     3961 atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg aaatccaaac
     4021 tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga gttggaagtg
     4081 gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga aatccctgga
     4141 attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaaga tgatgagaag
     4201 atttcagttc gtgagtttat tactaagcta gatgaaaaaa tggaattgct caacatgaaa
     4261 gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat
     4321 gaaattcttc aacttttgat gttggagcca acatttgctc ttttggacga gattgactca
     4381 ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa
     4441 ggttttggtg ctatgatcat cactcactac caacgtcttt tgaactatat cacacctgat
     4501 gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga attggctgcg
     4561 cgtttggaac gtgaaggata cgcaaaacta gctgaagaac ttggctacga ctacaaggaa
     4621 gaattgtaat tccctcgtat cttttaggag aagtaaatga ctagagaaaa tattaaactt
     4681 ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa agcttttgac
     4741 aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg ttggaatctg
     4801 ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt cacagcttta
     4861 gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca aactccagtt
     4921 gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga agaaattcca
     4981 gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa gttggcggct
     5041 taccacacag cttactttaa cagtggtgct gtactctata ttccagataa cgtagaaatt
     5101 acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc gtttaacaag
     5161 catattatga ttatcgctgg taaaaattct aagattagtt atctggagcg tttagagtca
     5221 cgcggtgaag gaagtgacaa agcaactgcc aatatcacag tggaagtgat tgcacgttct
     5281 ggtgcgcaag tcaagtttgc tgctatcgac cgtctaggtg aaaacgtcac tgcctacatt
     5341 agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg tgtcatgaac
     5401 gaaggaaatg tcgttgctga ttttgatagt gacttgcttg gaaatggtag ccatgcggac
     5461 ctcaaggtag tagcactttc aagtggtcgt caggtgcaag ggattgatac tcgcgtgact
     5521 aactatggtt gcaactctat cggaaatatc ctacaacatg gggttatcct tgaaaaagca
     5581 actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc agatgcccaa
     5641 caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa cccaattctt
     5701 ttgattgatg aaaatgatgt cactgcagga cacgcagcgt ctatcggaca agttgatcca
     5761 gaagacatgt attacctcat gagtcgtgga ttggataagg caactgcaga gcgtttggtt
     5821 gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa
     5881 atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggaagccta tgttagatgt
     5941 agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg aacctctggt
     6001 ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag ctattaacag
     6061 ctactatgaa caggacaatg ccaatgttca ccgtggtgtc cataccttag cggaacgagc
     6121 gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg catgctctac
     6181 aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg cacgctttgc
     6241 tgaggaaatt ctcactgagg gagaccaggt cttgatttca gtaatggaac accattctaa
     6301 tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct atgtctatct
     6361 taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata aggttaaatt
     6421 tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatta aggaaatcac
     6481 tcaattagcc caccaagttg gggcaatcat ggtagtggat ggtgctcaat ctacacctca
     6541 tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg gtcacaagat
     6601 ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc
     6661 tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatccg ctagttggaa
     6721 ggaattgcct tggaaatttg aggctggaac gccaaatatg gcaggagcta ttggacttgc
     6781 gactgcagtt gattatctgg aaaagattgg tatggatgcc gttgaagctc atgaacagga
     6841 attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca tttacggttc
     6901 tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc tccatcctca
     6961 cgatcttgcg acggctctgg attatgaagg agtggctgtt cgtgctggtc accattgtgc
     7021 gcaacccttg cttcagtatt tggaagtccc agcatcagct cgtgcaagtt tttatatcta
     7081 caataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa aggagttttt
     7141 caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac cattcgaaaa
     7201 atccacatca ccaagggaag ttagaagatg ctgagcaaat cagtctcaac aatccgactt
     7261 gtggggatgt catcaacctc tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg
     7321 cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg acagatgtcg
     7381 ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct gaaatggttc
     7441 aagggcaaaa agatgagcgt caaggccaac ttggagacgc ggcattcttg tcaggtgttg
     7501 ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa
     7561 ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta ttagaaatga
     7621 agaaagaaag gatactatgg ctgaagaaag agtagaacca aaaccaattg accttggtga
     7681 atataaattt ggtttccatg acgatgtaga gcctgtctta tcgacaggaa aaggactcaa
     7741 cgaaggtgtt attcgtgaat tatctgctgc taagggtgag cctgagtgga tgttggagtt
     7801 ccgtttgaag tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg gagcagactt
     7861 gtcagagatt gactttgatg acttaatcta ctaccaaaaa ccatctgaca aaccagcccg
     7921 ttcttgggat gatgtacctg aaaagattaa agaaaccttt gaacgtatcg ggattccaga
     7981 agctgaacgt gcttatttag caggggcttc tgcccagtac gagtcagaag tggtttacca
     8041 caacatgaag gaagagttcc aaaaattagg tattatcttt acagatacag attccgcact
     8101 caaggaatac ccagacttat ttaaacaata ctttgcgaag ttggtaccgc cgacagataa
     8161 caagttggca gccctcaact cagcagtatg gtcgggtgga acttttatct acgtgccaaa
     8221 aggtgtcaag gtagatattc cacttcaaac ttatttccgt atcaataacg aaaatatagg
     8281 tcagttcgaa cgtaccttga ttatcgttga tgagggagca agcgtccact acgtagaagg
     8341 atgtacagca ccaacatatt caagcaatag cttacacgct gccattgtag aaatttttgc
     8401 tttggacgga gcttatatgc gttatacaac tatccaaaac tggtctgata acgtctataa
     8461 cttggtaaca aagcgtgcta aggctcaaaa ggatgccact gttgagtgga ttgatggaaa
     8521 cttgggtgcc aaaacgacta tgaaatatcc atctgtttac cttgatggag aaggagcgcg
     8581 tggtaccatg ctctctatcg cctttgctaa tgcagggcaa caccaagaca cgggtgctaa
     8641 gatgattcac aatgctccac ataccagctc gtctattgtg tctaaatcca tcgctaaagg
     8701 tggaggaaag gttgactacc gtggacaagt cacctttaac aagaactcta agaaatctgt
     8761 ttcccacatt gaatgtgata ccattatcat ggatgacttg tcagcatcag atactattcc
     8821 atttaatgaa attcacaact cgcaagtagc tttggaacac gaagccaaag tatctaagat
     8881 ttcagaagag caattgtatt atctcatgag ccgtggattg tcagaatctg aggcaactga
     8941 aatgattgtc atgggatttg tagaaccctt tacaaaagaa cttccaatgg aatacgcagt
     9001 tgagctgaac cgcttgatta gctatgaaat ggagggatca gttggataaa atttgatttt
     9061 atactcttcg aaaatctctt caaaccacgt cagcatcgcc ttaccgtatg tatggttact
     9121 gacttcgtca gtttcatcta caacctcaaa acagtgtttt gagcaacctg cggctagctt
     9181 cctagttagt tctttgattt tgagtattag atttactcaa aatcaaggat tttgaagatg
     9241 aacttgtatc aaaaaatcgc ggtttaaaat cgcgattttt tataatttct cgttaacaaa
     9301 gcggacaaac tgattccacc aaacttttaa gaagaaggct ttttcaattt tcttgtctgc
     9361 taccatttcg aaactagggc gctctgtggt gatgtaacct tgaccaatca agtccttgtc
     9421 ttcataagtc aaatggccaa ccactgttcc agcttcaagt ggtgctggga ttgctttgga
     9481 atcaggtgtg aattgaacag attgggaaga ttgattccca acacgttcga ttagatagat
     9541 atcctctgga gccactgcag ttactgtatc ttcttttcca tcttgtacag gggctttgct
     9601 atcttgatag gcatcgcctt gttgaacgat tttgcgaagt gtaaatgtag aagaaatata
     9661 atccattagg gaagatgtag ctgtaaatcg agcgtaagga ttattgtctt gatgatctgc
     9721 atttaaaaca actgtgatga ctctcatgcc tttttcgaca gtagtaccaa caaaagactc
     9781 tccagcctta tctgttgttc ctgtttttag cccatcaaaa ccaccacggt aagcaggcat
     9841 accttctaac atgtagttgg ttgaagtgat tgtcatccca gcaaaagtag aagaaggttt
     9901 tttggtgatt tctaagactt gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac
     9961 atcataagca ctaagcttat tttcctcatc ttttttagaa cctgggtaaa tgttatcccc
    10021 tagagtttca ttgttaagac ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc
    10081 caagagtttt gcccgcatca tatcgacgaa atctttttct gagccagcaa ttttctcagc
    10141 tagggcaata gcggcgctgt tggcactaga taccagagtt gcttcaagca actcttcgac
    10201 agtataatta cgggcctcca taggaatatt actggcttca gaatttgtcg tcaattgata
    10261 aggataatca gaaatatcta caggagtgga gagggtaata cttccgtttt ccaaagcttc
    10321 atagaccaga taaacagtaa tcaattttgt tatggaagca atttcgacag gttgcgttgc
    10381 atccttctca tagagaattt taccagtatt tgcctcaaca gcaatcgcat gtttagcggc
    10441 aatggtaaaa tcttgagcaa cagcagtaga agcaccccct aaaagagaga cagttaacaa
    10501 agttaaaaat atttttttca tagtagtctt attctatcat aaagaaaaaa aatattcttg
    10561 ctttaataat tcatctgtta agctttttga aaatatggta aaataaagtg agggaggtaa
    10621 ctcatgtttc gtagaaataa attatttttt tggaccacag aaattttact cttaaccatc
    10681 atcttttatc tatggagaca gatggggtct ttgattaacc cttttgttag cgtgcttaat
    10741 acaattatga ttccattttt attagggggc tttctttatt atttgacaaa ccctattgtt
    10801 actttcttaa ataaagtctg taaactcaat cgtttgcttg gtattttaat taccttgtgt
    10861 actttgatct ggggaatggt cataggtgtt gtctatctct tacctatttt gattaatcag
    10921 ttatctagtt tgattatatc tagtcaaact atttatagtc gagtacaaga cttaatcata
    10981 gacttatcta attatcctgc gctccagaat ttggatgtag aagctacaat tcagcagtta
    11041 aacttatcct atgttgatat tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg
    11101 agcgtcttgt cagctcttat cagtactgtt ttgattttga ttatgactcc agtttttttg
    11161 gtttatttct tattagatgg acataaattc ttgcccatgc ttgaaagaac gattctaaag
    11221 agggatcgct tgcatattgc aggcttatta aagaatttaa atgcgacgat tgctcgctat
    11281 attagtggag tttcgattga cgcaatcatt ataggttgtt tggcttatat tggctatagt
    11341 attattggtt taaaatatgc tttagttttt gccatttttt ctggtgtagc caatttaatt
    11401 ccttatgtgg ggccaagtat tggtttgatt cctatgatca tcgcaaatat attcactgat
    11461 ccccatagac tgctgattgc agtgatttat atgcttgttg ttcagcaggt agatggcaat
    11521 atcttatatc ctcgaatcgt aggaagtgtt atgaaggttc atccaatcac gattttagtt
    11581 ttacttttgt tgtcaagcaa tatctatggt gtagttggaa tgattgtcgc agtgccaacc
    11641 tattctatct tgaaagaaat ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata
    11701 atgaaagaac gagaaagaga attagctaag taaaagtcag gagaaccctg atttttcttt
    11761 actggaagtg gcctttagat tagaagactg aaaataagtt aaagtcttaa actaattttc
    11821 acagctaaga atagtagaag ttaatctgat aaaaatcgaa aaaaccagtg gaattccgtg
    11881 tcagggtaag ttccactggt tttcatagtc tattaaagtt cgaatgaaac ctatttatag
    11941 tatattgaaa ctagaatagt acacctctaa ttctaaaaca ttgttagaaa tcgatttgac
    12001 tgtcctgatc tattcgtcct attcttattt cattttacta tattttggtg caataagtga
    12061 aaagtagtcc gaataatata aggattgatt ttatagtttt taaactcaaa tgaattaaaa
    12121 taaagagagt acgaaaattc tcatctgaaa gtattttaga ataattctct tcgtgaattt
    12181 cttcaaaaca gatagcttca tcttaggtat gtgttaattg gatttcgtaa gctctattta
    12241 caatcgtaaa gttatgcact gaaaaagttg tagttagtct tccagtttgc taaatttctc
    12301 gaatagtatc ttttttaggt atgtgatttc tttttgcatt tttgagttag ataaggtata
    12361 atggttttat tgtcttttgg ggtcgttacg gattcgacag gcattatgag gcatattttg
    12421 cgactcgtgt ggcgacgtaa acgctcagtt aaatataact gcaaaaaata acacttctta
    12481 cgctctagct gcctaaaaac cagcaggcgt gacccgattt ggattgctcg tgttcaatga
    12541 caggtcttat tattagcgag atacgattaa gccttgtcta gcggtttgat aagagattga
    12601 tagactcgca gtttctagac ttgagttatg tgtcgagggg ctgttaaaat aatacataac
    12661 ctatggttgt agacaaatat gttggcaggt gtttggacgt gggttcgact cccaccggct
    12721 ccattattcc tttgcattcc ttggtaaaac gttgttaaat caacgttttt tatttttatc
    12781 tttggtattc ctttgcattc ttttgctaaa aagggagtca caaacagacc ctattttaaa
    12841 aaaaggatag aaaaaaggat acaacatttg tcgcatccta aaaataatct tttttcgacg
    12901 gaagacatgg gattcgaacc cacgcacgct attacacgcc taccgcgttt ccaacacggc
    12961 ctcttaagcc tcttgagtaa tcttccaata cttactcaaa tagtctacca taaaggctct
    13021 tatcttgcaa taaaaattct agaaataaga aaaaatgata gattttgaaa gaaaatgata
    13081 aaaaatgctt gacttcgaaa gaaagtatgg tagaatgaat agtgtaaacg ataacaggag
    13141 gtgattcagt gttaaaaaca gaacgtaaac aactgatttt agaggagtta aatcaacatc
    13201 atgtagtttc tctagaaaaa ttagttagtt tgctagaaac gtcagaatca acggttcgaa
    13261 gagacttgga tgagttggaa gcggaaaaca agcttcgtcg tgtgcatggt ggagcagaac
    13321 tcccccactc cttacaggaa gaagaaacca ttcaagaaaa atctgtcaaa aaccttcaag
    13381 aaaagaagtt gctggctcag aaagcagcct ctctcattaa agaaaaagat gtcatcttta
    13441 tcgatgctgg aacaacaact gcttttttga ttcatgaatt ggtcaataag aatgttacag
    13501 ttgtgaccaa ctccattcac catgccgctc agttggttga aaagcagatt ccaactgtca
    13561 tggttggagg aaacgtcaag acggcgacag atgctagtat cggtggcgtt gctcttaacc
    13621 agattaacca attgcacttt gaccgtgcct ttatcggaat gaatggtgtt gacgatggct
    13681 attatacgac tcctgatatg gaggagggag ctgtgaaaag agctattttg gagaatgcca
    13741 agcagaccta cgtcttggtg gattcgtcaa aaattggaca aacttgcttt gccaaggtag
    13801 caccactcaa acgcgctatc gttatcacta gtcaagggca tgagctcttg caggttatta
    13861 aggagaaaac ggaggtaata gaagtatgat ttatacagtc acactcaatc catccattga
    13921 ctatatcgtt cgtttggacc aagtcaaagt tggtagtgta aatcgtatgg acagtgatga
    13981 taagtttgct ggtgggaaag gaatcaatgt cagccgtgtc ttgaaacgtt tgaatatacc
    14041 aaatacagcg acgggattta tcggtggctt tactggtaaa tttatcacag atactttagc
    14101 agaggaagaa atcgagacac gttttgtcca ggtggcagaa gatactcgta tcaatgttaa
    14161 aatcaaagca gaccaagaaa cagaaatcaa cggaacgggt ccaactgttg aatcggttca
    14221 gctagaagaa ttgaaagcta ttttatctag tctgacagca gaagatacag ttgtctttgc
    14281 aggttcaagt gctaaaaatc taggcaatgt tatctataag gatttgattt ccttgacgcg
    14341 ccagactggt gcgcaagtgg tctgtgactt tgaaggacag accttaattg atagtttgga
    14401 ctaccagcct cttcttgtaa aaccaaacaa tcatgaactt ggagcgattt ttggggttaa
    14461 actcgaaagt ttagatgaaa ttgagaaata cgctcgtgag ttactggcta agggtgctca
    14521 aaatgttatt atctctatgg ctggtgatgg tgcccttctt gtcacatctg atggagctta
    14581 cttcgctaaa ccaatcaagg gaacagtcaa aaattcagtt ggagctggtg attctatggt
    14641 tgctggattc acaggtgaat ttgtcaaatc aaaagacgca gtagaagcct tcaaatgggg
    14701 agtggcttgc ggaacggcaa ctaccttctc agatgacttg gcaacggcgg aatttattaa
    14761 agaaacatat ggaaaagttg aggtagaaaa acgatgaaaa ttcaagacct attgagaaaa
    14821 gatgtcatgt tgctagattt gcaggcaact gaaaaaacag ctgtcatcga cgagatgatt
    14881 aaaaatttga cagaccacgg ttatgtaaca gattttgaaa catttaaaga aggaattttg
    14941 gcgcgtgaag ctttgacttc tactggtttg ggtgatggaa tcgcaatgcc tcacagcaaa
    15001 aacgctgctg tcaaagaagc gacagttcta tttgctaagt caaataaggg tgttgactac
    15061 gagagcttgg atggacaagc aactgacctc ttcttcatga ttgcagctcc agaaggtgcc
    15121 aatgatactc acttggcagc cttggcagaa ttgtctcaat acttgatgaa agacggtttt
    15181 gcagacaaac ttcgtcaagc aacatctgca gaccaagtta tcgaactttt tgaccaagct
    15241 tcagaaaaaa ctgaggaact tgttcaagca cctgctaatg actctggtga ctttatcgta
    15301 gctgttacag cttgtacaac aggtattgcc cacacttaca tggcccaaga agcccttcaa
    15361 aaagtagctg ctgaaatggg ggttggtatc aaggtcgaaa ccaacggtgc tagcggtgtt
    15421 ggaaatcaac taactgcaga agatatccgt aaggctaaag ctattatcat tgcagcagac
    15481 aaggccgttg aaatggatcg atttgatgga aaaccattga tcaatcgtcc agttgctgac
    15541 ggtatccgta agacagaaga gctaattaac ttggctcttt caggagatac tgaagtctac
    15601 cgtgccgcta atggtgccaa agctgcaaca gcctctaacg aaaaacaaag ccttggtggt
    15661 gccttgtaca aacacttgat gagtggtgta tctcaaatgt taccattcgt tatcggtggt
    15721 ggtatcatga ttgcccttgc cttcttgatt gacggtgctt tgggtgttcc aaatgaaaac
    15781 cttggcaatc ttggttctta ccatgagtta gcttctatgt tcatgaaaat tggtggagct
    15841 gcctttggtt tgatgcttcc agtctttgcg ggttatgttg cctactctat tgctgaaaaa
    15901 ccgggtttgg tagcaggttt cgtggctggt gctattgcca aagaaggttt tgcctttggt
    15961 aaaattcctt atgccgcagg tggtgaagca acttcaactc ttgcaggtgt ctcatctggt
    16021 ttcctaggtg cccttgttgg tggatttatc gcaggtgcct tggttcttgc catcaagaaa
    16081 tacgttaaag ttcctcgttc actcgaaggt gctaaatcaa tccttctatt gccacttctt
    16141 ggaacaatct tgacaggatt tgttatgcta gctgtgaata tcccaatggc tgcaatcaac
    16201 actgctatga atgacttcct aggcggtctt ggaggaggtt cagctgtcct tcttggtatc
    16261 gtccttggtg gaatgatggc tgttgacatg ggtggaccag ttaataaagc agcttatgtc
    16321 tttggtacag gtacgcttgc agcaactgtt tcttcaggtg gttctgtagc catggcagca
    16381 gttatggctg gaggaatggt gccaccactt gcaatctttg tcgcaactct tcttttcaaa
    16441 gataaattta ctaaggaaga acgtaactct ggtttgacaa acatcatcat gggcttgtca
    16501 tttatcactg agggagcgat tccatttggt gccgctgacc cagctcgtgc gattccaagc
    16561 ttcatccttg gttcagcagt agcaggtgga ctcgttggtc ttactggtat caaactcatg
    16621 gcgccacacg gaggaatctt cgttatcgcc cttacttcaa atgctctcct ttacctcgtt
    16681 tctgtcttgg taggagcaat cgtaagtggt gtggtttatg gttacctacg caaaccacaa
    16741 gcataaaaaa tagaaaaatg aaaagattgg accgtttggt gcagtctttt tctcttcccg
    16801 aaatgcctgt gaaatatggt ataatagaag aatggcaaac aagaatacaa gtacaacaag
    16861 acggagaccg tctaaagcag aactggaaag aaaagaagcg attcaacgaa tgttgatttc
    16921 gttaggaatt gcgattttat tgattttcgc agccttcaaa ttaggggctg caggtataac
    16981 cctttataat ttaattcgct tgctagtggg tagcctagct tatctggcga tattcggcct
    17041 attaatctat ctcttctttt tcaagtggat acgaaaacag gaaggactct tatctggctt
    17101 tttcaccata tttgctggct tactcttgat ttttgaggcc tacttggttt ggaaatatgg
    17161 tttggacaag tccgttctaa aagggaccat ggctcaggtt gtgacagatc tgactggttt
    17221 tcgaacgact agctttgctg gagggggctt gatcggggtc gctctttata ttccaacagc
    17281 ctttctcttt tcaaatatcg gaacttactt tattggttct atcttgattt tagtgggttc
    17341 tctcctagtc agcccttggt ctgtttacga tattgctgaa tttttcagta gaggctttgc
    17401 caaatggtgg gaagggcacg agcgtcgaaa agaggaacgc tttgtcaaac aagaagaaaa
    17461 agctcgccaa aaggctgaga aagaggctag attagaacaa gaagagactg aaaaagcctt
    17521 actcgatttg cctcctgttg atatggaaac gggtgaaatt ctgacagagg aagctgttca
    17581 aaatcttcca cctattccag aagaaaagtg ggtggaacca gaaatcatcc tgcctcaagc
    17641 tgaacttaaa ttccctgaac aggaagatga ctcagatgac gaagatgttc aggtcgattt
    17701 ttcagccaaa gaagcccttg aatacaaact tccaagctta caactctttg caccagataa
    17761 accaaaagat cagtctaaag agaagaaaat tgtcagagaa aatatcaaaa tcttagaagc
    17821 aacctttgct agctttggta ttaaggtaac agttgaacgg gccgaaattg ggccatcagt
    17881 gaccaagtat gaagtcaagc cggctgttgg tgtaagggtc aaccgcattt ccaatctatc
    17941 agatgacctc gctctagcct tggctgccaa agatgtccgg attgaagcac caatccctgg
    18001 gaaatcccta atcggaattg aagtgcccaa ctccgatatt gccactgtat ctttccgaga
    18061 actatgggaa caatcgcaaa cgaaagcaga aaatttcttg gaaattcctt tagggaaggc
    18121 tgttaatgga accgcaagag cttttgacct ttctaaaatg ccccacttgc tagttgcagg
    18181 ttcaacgggt tcagggaagt cagtagcagt taacggcatt attgctagca ttctcatgaa
    18241 ggcgagacca gatcaagtta aatttatgat ggtcgatccc aagatggttg agttatctgt
    18301 ttacaatgat attccccacc tcttgattcc agtcgtgacc aatccacgca aagccagcaa
    18361 ggctctgcaa aaggttgtgg atgaaatgga aaaccgttat gaactctttg ccaaggtggg
    18421 agttcggaat attgcaggtt ttaatgccaa ggtagaagag ttcaattccc agtctgagta
    18481 caagcaaatt ccgctaccat tcattgtcgt gattgtggat gagttggctg acctcatgat
    18541 ggtggccagc aaggaagtgg aagatgctat catccgtctt gggcagaagg cgcgtgctgc
    18601 aggtatccac atgattcttg caactcagcg tccatctgtt gatgtcatct ctggtttgat
    18661 taaggccaat gttccatctc gtgtagcatt tgcggtttca tcaggaacag actcccgtac
    18721 gattttggat gaaaatggag cagaaaaact tcttggtcga ggagacatgc tctttaaacc
    18781 gattgatgaa aatcatccag ttcgtctcca aggctccttt atctcggatg acgatgttga
    18841 gcgcattgtg aacttcatca aggctcaggc agatgcagac tacgatgaga gttttgatcc
    18901 aggtgaggtt tctgaaaatg aaggagaatt ttcggatgga gatgctggtg gtgatccgct
    18961 ttttgaagaa gctaagtctt tggttatcga aacacagaaa gccagtgcat ccatgattca
    19021 acgtcgtttg tcagttggat ttaaccgtgc gacccgtctc atggaagagc ttgagatggc
    19081 aggtgtcatt ggtccagctg aaggtaccaa accaagaaaa gttttacaac aataaaaaaa
    19141 tagcttcttt ccaagtttgg aaggaggcta ttttagtggt tattgattac ttttattttc
    19201 tgaagttgga gtattgggct gtttttcatt ttcagtggca ggtttacttg tagcaggtgt
    19261 agtagagtcc tgagttgctg ttttctgatc ttcttttttc tcttccttga cgctagattt
    19321 tggtgtttcc tcttgctgtg ttttttcttg actagtgtta gtctctttag ttggactggt
    19381 gttttcctta ggggattcct tttggatttc tttgacaatg gttgtcgtct ggcttgtcgt
    19441 aggttctttt ttaatatttt tgttattatc caaggcgttc atgatcgtga tactcgcggt
    19501 aatcaagcca aggatactag cgattgtagc aacggttttt tgaaagactg taaagccttt
    19561 tttgatgtgt tctgtttttg gttttgaagt tctacgatag ttagacatac attctctcct
    19621 ttgattatga tttattatac tctgtttctt taaaaaaatc ttaaaaaaag agaaattgcc
    19681 ctttcttgtc gcaagctccg tttcatgata caatagagga agtgatttta gaaagcgtga
    19741 gaaacatgat ttactttgat aattcagcga cgaccaagcc ttatcctgaa gcccttgaaa
    19801 cctatatgca ggtcgcttca aaaattttag gaaacccatc tagtctccat agtttgggag
    19861 accaagcaac acgaatctta gatgcttctc gccaacagat tgcagattta atcggtaaga
    19921 aaagcgatga aatcttcttt acctctggtg gaacagaagg ggataactgg gttatcaagg
    19981 gtgtggcctt tgaaaaagct cagtttggca agcacatcat tgtttcagcc attgaacatc
    20041 cagcagtcaa agagtcagcc ctctggttga aaagtcaagg atttgaagtg gattttgctc
    20101 cagttgataa caaaggattt gtggatgttg aggcgctaga agatttgata agacctgata
    20161 cgaccctcgt ttccatcatg gctgtgaaca atgaaatcgg ctctatccaa cctattgagg
    20221 ctatttcaga attcttggca gacaagccaa ctatttcctt ccacgttgat gcggttcagg
    20281 cgcttgccaa gattccgact gaaaagtatc tgacagaacg agtggatttc gcgactttct
    20341 ctggtcacaa gttccacgga atccgtggtg ttggttttat ctatatcaag tctggcaaga
    20401 agattacgcc tcttttaaca ggtggtggtc aggaacgtga ttaccgttcg acaactgaaa
    20461 atgtggcagg aattgcagcg accgctaagg ctctccgttt atctatggaa aagctagata
    20521 tctttaggag caagactggg cagatgaagg cagtgattcg tcaagcactt ctggactatc
    20581 cggatatatt tgtcttttca gatgaggaag acttcgcccc tcatattctg acttttggaa
    20641 tcaagggtgt tcgtggtgag gtcattgttc acgcctttga agactatgat attttcatct
    20701 caacgacctc ggcttgttcg tccaaggctg ggaaaccagc cggaaccctg attgctatgg
    20761 gagtggacaa ggataaggct cagtcagctg tgcgtcttag tctagacctt gaaaatgata
    20821 tgagtcaggt cgagcagttc ttgaccaagc taaaattaat ttacaatcaa actagaaaag
    20881 taagatagga gcattcatgc agtattcaga aattatgatt cgctacggtg agctgtcaac
    20941 caagggcaaa aatcgtatgc gtttcatcaa taaacttcgc aataatattt cagacgtttt
    21001 gtctatctat ccccaagtta aggtaacagc agatcgcgac cgtgcccacg cttacctcaa
    21061 tggagcagat tacacagcag tagcagaatc gctcaaacaa gtatttggaa ttcaaaactt
    21121 ttcccctgtt tataaggttg aaaaatctgt agaagttctg aagtctgctg tccaagagat
    21181 tatgcaggac atctacaagg aaggcatgac ctttaaaatc tctagcaagc gtagcgacca
    21241 cacctttgaa ttggacagtc gtgaactcaa ccaaacgctt ggaggggctg tattcgaagc
    21301 cattccaaac gtacaagctc aaatgaaaag tcctgacatc aatcttcagg tggagatacg
    21361 tgaagaagca gcctatcttt cttatgaaac cgttcgaggg gcaggtggat taccagtggg
    21421 aacttctggt aagggcatgc tcatgttgtc agggggaatc gattcccctg tagctggcta
    21481 tctagcgctt aaacgagggg tagatataga ggcagttcac tttgccagcc caccttacac
    21541 gagtcctggt gctcttaaaa aagcccaaga tttgacccgt aaattaacca aatttggggg
    21601 aaatatccag tttatcgaag ttccttttac agagattcaa gaggaaatca aagccaaagc
    21661 gccagaagcc taccttatga ccttgacgcg tcgttttatg atgcgtatta ctgaccgtat
    21721 tcgtgaggta cgaaatggtt tagttatcat caatggggaa agtctaggtc aagtagccag
    21781 ccaaaccctt gaaagtatga aggctatcaa tgctgttacc aacactccca tcattcgtcc
    21841 tgtggttacc atggacaagt tggaaatcat tgacatcgcc caggaaatcg atacctttga
    21901 catttcaatc caaccgtttg aagactgttg taccattttt gcaccagatc gtccaaaaac
    21961 aaatcctaaa attaagaatg cggagcagta cgaagcgcgt atggatgttg aaggcttggt
    22021 tgagcgagca gtggctggaa tcatgattac tgaaatcaca cctcaagccg aaaaagatga
    22081 agttgatgac ttgattgaca atctgctcta attcagaaaa tccaaaagaa tagcgaaaat
    22141 cagtaaaaaa agttagtttt ttctctaaaa acaggtaaaa aactaacttt ttttattttt
    22201 atgatataat gatataaaat tttgaatata gagagttttc tgacaatgaa tcaatcctac
    22261 ttttatctaa aaatgaaaga acacaaactc aaggttcctt atacaggtaa ggagcgccgt
    22321 gtacgtattc ttcttcctaa agattatgag aaagatacag accgttccta tcctgttgta
    22381 tactttcatg acgggcaaaa tgtttttaat agcaaagagt ctttcattgg acattcatgg
    22441 aagattatcc cagctatcaa acgaaatccg gatatcagtc gcatgattgt cgttgctatt
    22501 gacaatgatg gtatggggcg gatgaatgag tatgcggctt ggaagttcca agaatctcct
    22561 atcccagagc agcagtttgg tggtaagggt gtggagtatg ctgagtttgt catggaggtg
    22621 gtcaagcctt ttatcaagca caaaacaggt tggtttgatg gcatgatgac gacaggttgc
    22681 tctatgggag cctatcatgc actcaatttc ttcctccagc atccagatgt ctttaccaaa
    22741 gtgattgctc tcagtggtgt ttacgacgca cgtttctttg tcggtgatta ctacaacgat
    22801 gatgctattt accaaaactc gccagtagat tatatttgga accaaaacga tggctggttt
    22861 attgaccgtt accgtcaggc agagattgtg ctgtgtacgg ggcttggagc ctgggaacaa
    22921 gatggtttac catcctttta caagctcaaa gaagcctttg accagaaaca aattccagcc
    22981 tggtttgctg aatggggaca tgatgtcgcc cacgactggg aatggtggcg taaacaaatg
    23041 ccttatttcc tcggtaatct ctatttataa aaggagttac ctatgaatta ccttgttatt
    23101 tctccctact atccacaaaa ctttcaacag tttaccatcg aactagctaa taaaggcatc
    23161 acagtcttgg gaattggtca agagtcttac gagcaattgg atgagccctt gcgcaatagc
    23221 ttgaccgagt attttcgtgt tgataatctt gagaacatag atgaagtcaa acgtgcagtt
    23281 gcttttctct tttataaaca tggtccaatt gaccgcatcg agtctcacaa tgaatactgg
    23341 cttgagctag acgcaacact cagagaacaa ttcaatgttt ttggtgccaa accagaggat
    23401 ctcaaaaaga cgaaatataa gtctgaaatg aagaaacttt tcaaaaaagc aggtgttcct
    23461 gtggtacctg gagctgttat caagacggaa gcagatgttg atcaagcagt gaaagaaatc
    23521 ggtcttccaa tgattgccaa acctgataat ggagtgggag cagccgcaac ctttaaactt
    23581 gagacagaag acgatatcaa tcacttcaag caagaatggg accattcaac cctttatttc
    23641 tttgaaaaat ttgtcacttc cagcgaaatc tgtacctttg acgggctcgt ggacaaggat
    23701 ggaaagattg tcttctcaac aacctttgac tacgcctata caccgcttga cctcatgatt
    23761 tataagatgg acaattctta ttatgtgctc aaggatatgg atcctaaact gcgcaagtat
    23821 ggggaagcaa ttgtcaaaga atttggtatg aaagaacggt ttttccatat tgagttcttc
    23881 cgtgaggggg acgattatat taccatcgag tacaataacc gccctgcagg tggttttacc
    23941 attgatgttt ataactttgc tcattccttg gacctttatc gtggctatgc agctattgtc
    24001 gcaggagagg agttcccggc gtcagacttt gaaactcagt attgtttggc tacttctcgc
    24061 cgtgcaaatg ctcactatgt ttattcagaa gaggatttgc ttgccaaata tagccagcag
    24121 ttcaaggtta aaaaagtcat gccagctgcc ttcgcggaac ttcaaggaga ttacctgtat
    24181 atgctgacaa ctccgagtcg acaagaaatg gatcagatga ttgctgattt cggacaacgt
    24241 caagaataag aactatcgga ttaaggaaat tcactccctt aatccttttg ttttgtctgg
    24301 taaaaaataa gagcatccta acaaggtagc tatcataaaa cttgttcgat aactatttga
    24361 agcaggatta ggtggctaga aattgaattt taacatttca atttagtcat agtattgtgt
    24421 tttcgtatcc ttaaatcagc taaaaggatc catgacgaca cctatacgat atagttttca
    24481 agataccaaa caagtctatt aatattcaat gaaaatcaaa gagcaaacta ggaagctagc
    24541 cgcaggtttc tcaaaacact gttttgaggt tgtggataga actgacagag tcagtatcat
    24601 atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttcgaagag tataaaatat
    24661 tcaggtgacg catagatata gttaattgaa gctttgtttg aaatctgata aaataatgat
    24721 attactaagt tttaaaaact aaagaaaagg gaagatatga ttacaggcga attaaaaaat
    24781 aaaatcgatc agctgtggga aattctttgg acagaaggaa acgcaaatcc tttaacaaat
    24841 attgaacagt tgacttatct cttatttatg aaagatttgg atagtgtcga gcttggacgt
    24901 gaaagtgatg ctgaatttct agggattcct tatgagggag tttttccaaa agataaacct
    24961 gaataccgtt ggtcaacttt taaaaatata ggagatgctc aggaagttta tcgtttaatg
    25021 actcaggaga tttttccgtt tattaaaaat ctcaaggggg atacagatga tacagccttt
    25081 tcacgatata tgcgagaagc tatttttcaa ataaataaac ctgctacgct tcaaaaggca
    25141 atttctatct tagatgtttt tccaactagg ggattagatg tagattttga taatgacaaa
    25201 caaagtatta ctgatatcgg agatatctat gaatatctgt tatcaaaatt gtcgaccgca
    25261 ggtaaaaatg gacagttccg tacacctcgt cacatcatcg atatgatggt tgagttgatg
    25321 caaccgacta tcaaagatat catctcagat cccgctatgg gttctgctgg cttcttagta
    25381 tctgctagcc gttacttaaa gcgtaagaaa gatgaatggg aaaccaatac agataatatc
    25441 aatcattttc ataatcagat gtttcatgga aatgatacgg atacgactat gttgagactt
    25501 ggggcgatga acatgatgct acatggagta gaaaatccac aaatcagtta ccttgactcg
    25561 ctgtctcaag ataatgaaga agccgataaa tatactttgg ttttagcaaa tcctcctttt
    25621 aagggctcac ttgactacaa ttcaacctct aatgaccttc ttgcaaccgt aaaaaccaaa
    25681 aaaacagaat tactctttct ttctcttttc ttgcgaactt taaaaccagg tggacgagca
    25741 gcagttatcg tacctgatgg tgtccttttt ggttcgtcta aagctcataa aggaattcgt
    25801 caggaaattg tagagaatca taagcttgat gctgtaatct caatgcctag tggtgtgttc
    25861 aagccttatg ctggagtttc aactgccatt ctcatcttta caaaaactgg taatggtggt
    25921 actgacaaag tctggtttta cgatatgaaa gcggatggtt taagtttgga tgataagcga
    25981 caaccgatta gcgacaatga tattccagat attatcgaac gctttcatca tcttgaaaaa
    26041 gaagcagaac gtcagagaac ggatcaatct ttctttgttc cagttgctga gataaaggaa
    26101 aatgattatg atttgtctat caataaatat aaagagattg agtatgaaaa agttgagtat
    26161 gaaccaacag aggtcatctt aaagaaaatc aatgatttag aaaaagaaat tcaagctggc
    26221 ttggctgaat tagaaaaatt actcaagtag agaggtggct gtatgaaaaa agtgaagttg
    26281 ggggaagtct tatctctaaa aaaaggcaag aaagccactg tacttgctga acaaacaact
    26341 ctaagccaac gttatattca aatagatgat ttaagaaata ataataattt aaaattcact
    26401 gaaagtttaa atatgactga agcactccca gatgatattc tgatagcatg ggatggagct
    26461 aatgcaggaa cagttggtta tggattatcg ggagctgttg gtagtacaat tacggtctta
    26521 aaaaagaatg agcgatacaa agaaaaaatt atatcagatt acttgggagt ctttttggaa
    26581 agtaaatcgc agtatttacg agaacattca acaggtgcaa caattcctca tttaaacaag
    26641 aatatattac ttgatttaca attagaattg ctaggtatcg aagaacaaga gaacattatc
    26701 tgtattctta atacgattaa aaggcttatt actaaaagaa aattgcagtt agatgaacta
    26761 aacttgctcg tcaaatcccg atattccgag gaggtggttg catgaagaaa gtgaaattag
    26821 gggaagtggc tacttttatc aatggctatg cttttaaacc tcaagattgg tcatctgaag
    26881 ggagagagat tatcagaata cagaatctga ctaaaacttc aacagagata aattattatt
    26941 cgggtacgat tgataaaaaa tacattgttg aagctggtga tatccttatt tcgtggtcgg
    27001 gtacattagg ggtttttcag tggtgtggaa gatccgcagt attaaatcag cacattttta
    27061 aagtggtttt tgataagata gatatagata aatcgtattt taaatatgtt gttgaaaaag
    27121 gtttacaaga tgctgtaaaa catactcatg gttccacaat gaaacattta actaaaaaat
    27181 attttgataa tattatagtt ccatatacaa atttgggaga gcaacaaaga attgcaagtg
    27241 agctggattt gttaagcaag ctgattttaa ggagacaaga acaacttgaa gagcttaatc
    27301 tacttgtaaa atcccgattt aacgagatgt ttggggaaaa taaaatattt gaaagcattg
    27361 ataacttatt tgatattata gatggtgata ggggcaaaaa ttatcctaaa tcagatgagt
    27421 tgtttagtga ggagtactgt ttatttttaa atacaaagaa tgttactaaa aacggatttt
    27481 cattcgatac aaagcaattt atcactaaaa caaaggataa attacttcga aaaggcaaac
    27541 ttgagcgtta tgatatagtc ttgacaacaa gaggtactgt tggaaatgta gcgtactacg
    27601 atgaattaat aaaatataaa catttacgta taaattcagg tatggtaata ttacgtccca
    27661 agacaccaaa tctaaatcag aaatttatta tccatgtttt aaggaataat aattatagtc
    27721 gagtgatatc aggaagtgct cagcctcagt taccaattac aaaattaaaa aaaatacttc
    27781 tccccctccc cccactagcc ctccaaaatg agttcgcaga ctttgtagcc caggtcgaca
    27841 aatcacaatt ggcaatccaa aaatctctgg aagaacttga aactttgaag aaatctctga
    27901 tgcaggagta ttttggctga tattctgcca ttgtaattac ggtaatgatt tgttataata
    27961 cttcaaagga ggaaatcaga tggtagtaaa aacaagaaaa caaggaaatt caatcaccat
    28021 tacgattcca agtgaattta atattccaag tggtgttaaa tacgaagcga aattgttacc
    28081 aagtggtgag attatcttta ctcctgaaga attggggcag caggtttctt atgtatctga
    28141 tgatgccttt gacttaaatt tagataaaat atttgacgaa tacgacgatg ttttcaaagc
    28201 tttggtggaa aaatgacaat ctatctgaca gaaaagcaaa ttgaaaaaat aaatgcttta
    28261 gcaattcaac ggtattctcc aaatgagaaa attcaaacag ttagttcttc tgccttaaat
    28321 atgattgtga acttaccaga acaatttgtc tttgggaagt ctctttatcc aacaattttt
    28381 gataaagcaa cgatactatt tgtccaattg ataaagaagc atgtttttgc taatgctaat
    28441 aaaagaactg ctttcttcgt tttggtcaaa tttttacaat taaacggcta tcgtttttct
    28501 gtaacggtag aagaagcagt aaaaatgtgt gtaaccatcg cagtagaagc tttaactgat
    28561 gaaaaaatga caagctactc caaatgggtt tctgaacatt ctgttagaga aaaggtcaaa
    28621 aagtaaccta gtatgctgga tttgaatgag cacaagaaaa taaatgaaca gacaatatta
    28681 gaattctgta atgcagaaac tgatattgtc tctttttatt gatgaataag aaagtgagaa
    28741 attatggaat caaaagttac aattatcatg caagaaatgt tacctctttt aaataatgaa
    28801 caattactag cgttgagaga gagtttagaa catcatctag tagacggaaa aaagcagcag
    28861 aagtattcga ataataacct gttgcaacta tttattaccg ccaagcaggt agagggctgt
    28921 agctcaaaaa caattcgtta ttaccagagg acgattgaaa acttgtttaa tgctattaaa
    28981 gagtctgtga cacaactcac aacagatgat ttaaggagtt atttagcaaa ttaccagtct
    29041 gaaaaggatt gtagtaaggc aaatttagac aatattaggc gtatattgtc ttcttttttt
    29101 gcttggcttg agcaagagga atatatcatt aaaaatccca ttcgacggat aaagaaaatt
    29161 aagactgagc aaaatgtgaa ggaaacttat actgatgaac atttggaaat tatgcgtgat
    29221 aactgtgaaa atttgagaga tttggcaata atagacctac tagcatcgac aggtatgcgt
    29281 gtaggggagc ttgtacagtt gaatcgttca gatattgatt ttgaaaacag agagtgtgtt
    29341 gtctttggta aaggaaagaa ggagagacca gtatattttg acgctcggac gaaaattcat
    29401 ttaagaaatt atcttaacga cagaaaagat agtcaccctg ctctttttgt aacgttagtt
    29461 ggaaaagtcc agaggcttgg aattgctggt gtagagattc gcttaagaaa gttaggagac
    29521 aaactcggta tacaaaaggt tcacccacat aagttcagaa gaactttagc gactaaggca
    29581 attgataaag gtatgcctat cgaacaagtc caaaaactgc taggtcatag caagattgac
    29641 acaaccctgg cctatgccat ggtcaatcaa aataatgtca agcattcaca ccaaaaattc
    29701 atctcttaaa agcaaatccc gatttaacga gatgtttggg gatgttattc taaatgaaaa
    29761 agaatggaaa gttagcaaat ggaacgagat tctaacaata agaaatggta aaaatcaaaa
    29821 acaggttgaa gatgctgatg ggaaatttcc tatttatgga agtgggggaa ttatgggata
    29881 tgctaaagat tggatagtga agaaaaattc agttattatt ggacgtaaag gaaatataaa
    29941 taaacctatt ttagttagag aaaatttttg gaatgtagat acagcatttg gattagagcc
    30001 tgttttagaa aaaataaact cagaatattt attctatttt tgtcaattat acaattttga
    30061 gaagttaaat aaggctgtaa caatacctag tttaactaaa tcagatttat taaatatttc
    30121 catccccctc cccccactag ccctccaaaa tgagttcgca gactttgtag tccaggtcga
    30181 caaatcacaa tttgcttgtg agatagctat aaaagtgtgg agaaatagct tgaaatttag
    30241 tataatatag ctaaactatt tgtttaaagt gagaaaaaaa tgggaaattt tagctttctt
    30301 ttaaaaaatg acgaatatga atctttttca aaaccttgca ttgaagctga aaatatgatt
    30361 gctacatcaa ctgtggctac tgcctttatg gcgcgtcgtg ctttggagca ggctgtccat
    30421 tggatatata gtcacgattc atatttagaa gctccctatc gtgctactct atcttcttta
    30481 gtatgggatg atgattttag ggatatcgta gattctgaac tccacaagca gatagttctg
    30541 ttgattcggt ggggaaacca tgctgctcat ggtggtgaaa ttaaggaacg agaagcgatt
    30601 ttagctttac atcatttgta tcagtttgtt aattttatcg attattgtta cagcaatgaa
    30661 tttgtggagc gttattttga tgagaagtgc ttaccacttt cagcaaacat caaataccga
    30721 gaaactccac aatctatgat aaagttacaa gacagtttac cagaactgcc tgattttcat
    30781 gaacagatgg ctgctcagtc cgtagaagtt caagagactt atactgaaaa acgtgagact
    30841 gcagcgcaac ggcaagatgt gcctttccat attgaacaat tatctgaggc agagacaaga
    30901 aagctcttta ttgatatcga tctccgttta gcaggatgga tatttgaaga aaactgtcgt
    30961 gttgagatag ccgttgatgg tctcaagcac ggttcaggaa ttggttactg tgactacgta
    31021 ctttatggta aaaatgggaa aattttagcg attgtggagg ctaaaaaagc ctctgtcaat
    31081 ccagaagtag gggaagtaca ggtcaaagaa tatgctgaag ctttggagaa acatatcggc
    31141 tatcagccaa tttgctttat tacaaatggg ttgaagcact atatacttga tggtccgaac
    31201 cgccgccaga ttgcaggctt ttactctcaa gaagaattgc aattagtgat ggatagacgt
    31261 catcttcaaa aaccgcttga ggatatttct agtaaaatta gggacgatat ttccgggcgt
    31321 cactaccaaa aacatgccat tgcaagcgtt tgtgaagctt tctctaatca tcgtagacag
    31381 gcacttttgg ttatggcaac tggggcgggg aaaactcgta cagcagtttc tctagttgat
    31441 atcttatcac gtcataactg ggtaaaaaac gttctcttct tagccgatag aacttccttg
    31501 gttaagcaag cctatgattc gtttagaaaa ttactcccag atctttccgt ttgtaacttc
    31561 ttagaagata aagaaggagc tcaatcaagt cgtatggtct tttcaactta tccgaccatg
    31621 attggagcga ttagtggtca agaagaagta aatcaacgcc cttttactgt tgggcatttt
    31681 gaccttatca taattgacga atctcaccgt tctatttatc agaaatacaa gtccattttt
    31741 gattattttg atgcaagaat tgtaggctta acagctactc cgcgtcaaga tttagataaa
    31801 aacacctatg gattctttaa tttggagaat ggggttccaa catatgcata tgatttggaa
    31861 gaggctgtta aagacggata tttagtagcc tatcattcta tcgaaaccaa actgaaacta
    31921 cctacggatg gtctacatta tgatgatttg tccgaagaag aaaaggaaca ttttgatagc
    31981 aaatttgaag acgatagctg tgaaaaagat attgatggga gtgtgtttaa ttcctttatt
    32041 ttcaataaaa gtacagtaga aattgtttta aatgaactca tgacaagagg aattcagaca
    32101 gcctcgggtg atgaaattgg taaaactatt atttttgcta aaaatcatga ccatgcggaa
    32161 tatatcagag gtatttttaa caaccgctat cctgaaaaag ggagcgacta tgctcaggtg
    32221 attgattata gtattaagca ttatcagacc ttgattgatg attttaaaat taaggagaag
    32281 tatcctcaaa ttgcgatttc tgtcgatatg ttagatacag gtattgatgt accagaggtt
    32341 gttaatttag tcttcttcaa gaaagtacgc tctaaaacta agttttggca gatgattggt
    32401 cgaggaaccc gtctatgtaa agatttattt ggacctgagc aggataagga aaacttcttg
    32461 gtatttgatt atggggataa ttttgattat tttcgtgcag atccaagaga tggagagggt
    32521 cgtcacattg tttcgttgac tcagcgttta tttaatatca aagtggactt gattcgagaa
    32581 cttcagggac tccaatacca agaagatcag tttgcgagag cataccgtca gcagcttgtc
    32641 tcggaacttc aaggtcgtat agagagctta aatgagttgg acttcagggt tcgtatggtt
    32701 ttagatacag tttatagcta taggaaattg gaaagttggc agaatctaac tgctgttaca
    32761 agtgaaacca ttcaaaaaaa tctctctccg cttttatttg atgaagataa agaagatgag
    32821 atggcgagga gatttgattt gtggttgctt catattcagt tggggcaact gacagctaaa
    32881 tcttccactg ttcatatttc ccaagtgatg aagacggcta gagctctttc tgctattggc
    32941 aatatcccgc aggtttttga gcaggctgaa attatcagga aagtacagga gcctgaattt
    33001 tggaaagaag ttaacttgtc tgatttggaa aaaattcgtc ttgctattcg agatttatta
    33061 cagtttttgg ataaaacaga ccgtaaaccc tactatgtta actttgaaga tcgtatactc
    33121 tccactgttc acgagaccac agcatttttg caggtcaacg atcttcggtc ttacaatgaa
    33181 aaagttgagc attatttgaa aactcatctg gatgaggagt ccatttctaa gctataccat
    33241 aataaaaagt tgacatctga tgatatgctt gcacttgaaa aattgctctg ggaaaaatta
    33301 ggtagtaaag cagactacca aagtcattat gaaaataagg caattccgag attggttcgt
    33361 gagattattg gcttagatag agagtctgcc aatcgtattt tttctaaatt tttgtcggat
    33421 gagaatctta atgccaggca gatttcattt gtaaaattga ttgtagacta cattgtagaa
    33481 aatggttttt tagagacgaa agtgttaacg caagagccgt ttaaatctta tggttctgtt
    33541 caactactct tccaacacca actaccagta cttcgtaata ttgttcaaat cattgaactt
    33601 atcaataatc gagctggaga agcggcttaa attctaaagt gattgccatg ctgagactca
    33661 tttaaaatta aaaagagtag aaatttatgc tatatatgag aagttttatt aggaagaatg
    33721 tcatcgtttt cctagaatac agtatcagtt gttaagtggt tgataaattt caaagtagat
    33781 acttgtacca cgatgtttgt tgatcgagtt attaacaaaa gagctacttt gattttaaag
    33841 aaatagaaaa caaaaagccg agcaagaatt caattgcagg agaaaatgaa ataatactca
    33901 atgaaaatca aagagcaaac taggaaacta gctgcaggct gctcaaaaca ctgttttgag
    33961 gttgcagatg gaagctgacg cggattgaag agattttcga agagtataaa tcttcctagg
    34021 ataaagcaaa acgcatagta tcaagggttt tcaacacttg atactatgcg ttttctgatg
    34081 ttaaagactt tctaccaggt tttttaaaag cataattgtt agttgtagtc atttattatt
    34141 cttcaaagaa aaatggtggg gcgaattttt tcagttcttc aaagcacttt tgagcagtat
    34201 ctgcatcttc acagatgata agacagacat cattaccaca aagggtagcg atagcgtcag
    34261 ggaagctcaa agtatcaatg atagaaccaa aggattgagc cagtccagga agggttttta
    34321 gtaggacttg gtgttgaact gggcgcatcc agacaagggc gtcttccatg tagagttcga
    34381 gacgtttttc ccattttgag atggaaccat tgttaagaac ataataagcg ctatcttctt
    34441 cgcggacttt tgataggttc atatttttga tgtcgcgtga gagggttgcc tgggttactt
    34501 gaatgtcgtt ctcagcaaga agggcttgca actcagcctg tgtatgaatc ttgttttttg
    34561 tgataagagc gcgtataagt tggtggcggt gttctgattt attcataata atgtaactcc
    34621 ttttagcaag gtaaggtaag catggactga gcgaggtcga cagtcaagtg gtagtctgta
    34681 ttgtcacgga tggtgatttc aaagtcagta gtatagagga ctaaacggag agtgtctcct
    34741 tcttttagct tgtaaatagt tggctgcagt tcaaattgaa cgtccatcca ttcatctgca
    34801 gtaatatcct ctactaacag taaatcattt ctattttgta aattaaggta accttttgtc
    34861 acgactcgtt gtgcctctgg tctaaatggc aattcacaga gattttccaa catgtgatag
    34921 cgaccgttgt caatggttct agcacttaaa atagctggat aaggttgtag gtatttcttt
    34981 tgcccaaatt ctagcagttg ggcagataag agccccttgt ttgtactgga tttgatacga
    35041 agattgagct gagcgcgacc gtttaggtgg agatctttag tcacaggaag gttaatagta
    35101 atctgattgg ctttcccttg atagagctct gtattgaagg tttggtatgt cttaccatag
    35161 cgctcaaaat ccttatctgg gtactggttt tgaatagctt gctcttcttg accaagtgag
    35221 aaggtttcac agttttcttg cccaccgaag ttatcaagtg ataaccaagt ctgtggagct
    35281 gtattgtcct gccagataac agtaggaagt tgaaagtctg tttcctgtcc tagtaatttc
    35341 ttggtcaata aggcatttat ggactcacgg aagtcaattg attgccaatt gttcatgtaa
    35401 acatgggcac cattatggaa aaagagatgc ttgtgtatat gagtaggaag agcatggaac
    35461 atctggtaaa catgaagtgg tttgacattc caatcctgag aaccatgagt aaagacaacc
    35521 tctgccttta ctttatgggc attgagcaga taattgcggt catgccaaaa ctgattgtag
    35581 tccccagttt ttcggtctag ctgagctttc actttttcta agtcagcttg gtgagcttca
    35641 ttaccacgga tatagtcgcc agctaagaga ttacgagaat aggttaactc agcaagggag
    35701 tcaaagtcct cacctggata accacctggg ctagtcacca gaccgttttc acggtagtag
    35761 ttgtaccatg atgaaattcc tgcctcggca atgataactt ctaaaccatc gactcctgta
    35821 gtcgcaagac cattggacat ggtacctaga taggaaagtc ctgttgtagc aacttttccg
    35881 tttgaccaat cagccttgac ttgacgctgg cgcgtgtgat cagtaaaggc acggcaacgg
    35941 ccgttaagcc aatcgatgac atttttataa gcctcgattt gctggtagtc tccattagtc
    36001 atgaaacctg tcgagtcttt ggtaccaaca cctgagacat agagattggc aaagcctctc
    36061 ggaaggaagt agtcgtttag tgtatagcta gagttgatgt gagttagctt ttcctcagcc
    36121 tctgctataa gctcagcttt accttggggt tggacgagat ttagttgagg tttctctagc
    36181 tcaatcttgt gaggaagctt aacctcaagc tcgccctcca tcttgtagag agccttgtca
    36241 ctagccttgt cattggttcc ctgatgataa gggctggctg tcatgatggc agggattttt
    36301 ccatcaaaac gagggcgaat aatgctaacc tttactaggt ctgatagccc tttttggtca
    36361 gtatcgacac gagactcaac gtaaacgact tcacgaatga catcctggtt agaaaaagta
    36421 gccaaactct tgccgttaaa gtagtggtag tcattatcct ccggaataag accatcacta
    36481 acaagttggt cgataagagt atttcctttt ttggtgcgag tattgagtaa ctgatagaga
    36541 ttttcaatca agtcaccata tataatggga aatccagttt ctttacgaaa aacgtcacta
    36601 tcttcgaagt caaccaaata agaaaagcct aaaagttgaa aagcaacagt ataaaaaata
    36661 tctgctgtca gttcatcttc tgattgaaaa aatgtcagca ggtctgtttt tttatcagct
    36721 gctaggatag aaagtgggta gttggtgtct tgataagtga aaaagaaacg acgtaaaaag
    36781 gtttcaagtg agtctttgtg attggctgta ttttgtaaat caaagccaca tttttttagt
    36841 tcagataaga cattttcttt tggaaaattg atataactat attgattaaa acgcatagaa
    36901 cctccatata gaatgacagt taaggttatt atatcaaaaa aaaagcagaa agggaattgt
    36961 taacttcaaa aggaaataat ccaataaaaa tgaataaagt actaaattca atatagagaa
    37021 cagagtaaca ataagaataa atagataggg tataaaagtt ctaggagatt tatattatat
    37081 gctttctatt tttatataca atatagtata aatataaaaa tgatgacaaa aatacaaatg
    37141 aatagaaaat aaattagtaa gctgatgaaa tttttctcaa gagaagccat ttataggtga
    37201 aaatggtata atatagtgag aaggatagag gagaagtgta aattgatcgc acaactagat
    37261 acaaaaacag tctatagttt tatggaaagc gtcatttcga tcgaaaagta tgtgagagca
    37321 gctaaagaat acggctacac tcatttggct atgatggata ttgacaatct ttatggcgct
    37381 ttcgactttc tagagattac aaaaaaatac ggcattcatc ctttgctagg gcttgaaatg
    37441 acagtgtttg tagatgatca gggagtgaat ttgcgctttt tagctctatc tagtgtgggc
    37501 tatcagcagt tgatgaagct ttcgacagcc aagatgcagg gggagaaaac ttggtcagtc
    37561 ctgtcccagt acctggagga tatcgcggtc attgtgcctt attttgatag agttgagtcg
    37621 ttagaactag gctgtgatta ctatataggg gtttatccag aaacactagc aagcgaattt
    37681 catcatccta tcttacctct ttatcgggtc aacgcttttg aaagcaggga tagagaagtt
    37741 cttcaagttt taacagcgat taaagaaaat ctaccgctca gagaagttcc cttgcgttcg
    37801 agacaagatg tctttatatc agcaagttct ttagagaaac tattccaaga gcgttttccg
    37861 caagctttgg acaatttaga aaagcttatt tcaggcattt cttacgactt ggatactagt
    37921 ctgaaactgc ctcgttttaa tccagctaga ccagcagtag aggagttgag agagcgtgct
    37981 gaactggggc ttgttcagaa ggggttgact agtaaagaat atcaagatag actagaccaa
    38041 gaattgtctg ttattcatga tatgggcttt gatgattatt tcttggttgt ttgggatttg
    38101 ttgcgttttg gacaatcgaa tggctattat atgggaatgg gaaggggttc tgcagtaggc
    38161 agtttggttt cttatgcctt agacatcacg gggattgacc cagtagagaa aaatctgatt
    38221 tttgaacgct ttcttaatcg tgaacgctat accatgcctg atattgatat tgatatccca
    38281 gatatttatc gtccagattt tatcagatat gttggtaata aatatggtag taaacatgcg
    38341 gcacaaatcg ttactttttc aacctttgga gccaagcaag ctcttcgaga tgtcttgaaa
    38401 cgctttggtg tgccagagta tgaattatct gcaattacta agaaaatcag ttttcgtgac
    38461 aatcttaagt cggcctatga gggcaatctc cagtttcgtc agcaaatcaa tagtaagtta
    38521 gaataccaaa aagcttttga gattgcttgc aagatagagg gctatccaag gcaaacctct
    38581 gtccatgcgg ctggtgttgt aattagtgac caagatttaa ccaactacat tcctctaaag
    38641 tatggtgatg aaattccact gactcagtat gatgctcatg gagttgaggc tagcggactt
    38701 ttgaagatgg actttctggg actacgaaat ttgacctttg tccagaagat gcaagagttg
    38761 cttgctgaaa cagaaggtat tcatctgaaa attgaagaaa tcgatttaga agacaaagaa
    38821 acgttagctt tatttgcctc tggtaataca aaaggtatct ttcaatttga gcaaccaggt
    38881 gccattcgtc tgcttaagcg tgtgcaacca gtctgttttg aagatgtcgt cgcgactact
    38941 tctctaaatc gaccgggtgc tagtgactat atcaataatt ttgtggcaag aaagcatggg
    39001 caggaagaag tgactgttct ggatccagta ctggaggata ttttggctcc aacctacggc
    39061 ataatgctct atcaggagca ggttatgcag gttgcccagc gacttgccgg atttagtctt
    39121 gggaaagccg atattttgcg tcgggctatg gggaaaaagg atgcctctgc catgcatgag
    39181 atgagggctt cctttattca aggttcatta gaagctggtc atactgtgga aaaagcagag
    39241 caggtctttg atgttatgga gaagtttgca ggttatggtt ttaacaggtc acacgcctat
    39301 gcctactcag ccttggcctt ccagttggct tatttcaaaa cgcattatcc agccattttt
    39361 tatcaggtca tgttaaattc ttccaacagt gattacttaa tagatgcact tgaagcaggt
    39421 tttgaagtag cctctctatc catcaacacc attccctatc acgataaaat tgccaacaag
    39481 gccatctatc taggtttgaa atccattaaa ggagtcagta atgatttagc tctctggatt
    39541 attgaaaata gaccttattc taacattgaa gattttatag ctaaattacc tgagaattat
    39601 ctgaaacttc ctctgctaga acctttggta aaagttggtc ttttcgattc atttgaaaaa
    39661 aatcgtcaaa aagtatttaa taacttagct aatctatttg aatttgtgaa agagttggga
    39721 agtttgtttg gagatgctat ttatagttgg caggaatcgg aagattggac ggaacaagaa
    39781 aaattttata tggaacaaga gcttttaggg ataggtgtca gcaaacatcc actacaagct
    39841 attgcaagta aggctattta cccgattacc ccaatcggaa atttgtcaga aaatagctat
    39901 gctattatct tggttgaagt tcagaaaata aaagtgattc gtaccaaaaa gggtgaaaat
    39961 atggccttct tacaggcaga tgatagtaag aaaaaattgg atgtcactct cttttcagac
    40021 ttatatcgtc aggttggaca ggaaataaaa gagggagcct tctactatgt aaaaggaaaa
    40081 atacaatcac gtgatggccg tctgcaaatg attgcacaag aaataagaga agcagttgct
    40141 gaacgctttt ggatacaggt gaaaaatcat gaatcggatc aagaaatttc acgcatttta
    40201 gaacaattta aaggcccaat cccagtcatc atccggtatg aagaggaaca gaaaaccatc
    40261 gtttctcccc atcattttgt agctaaatcc aatgaattag aggagaaatt gaatgaaatc
    40321 gttatgaaaa cgatttatcg ctaaaaatac ggaaaataga agaattttca acgtaaatgt
    40381 ggtataatca gtaagaatgt taaaagaaaa aggagcataa ccaatatgaa acgtattgct
    40441 gttttgacta gtggtggaga cgcccctggt atgaacgctg ccatccgtgc agttgttcgt
    40501 caagcaattt cagaaggaat ggaagttttt ggtatctatg acggatatgc tggtatggtt
    40561 gccggtgaaa ttcatcccct agatgcagct tcagtagggg acatcatttc tcgtggtggt
    40621 actttccttc actcagctcg ttacccagag ttcgctcaac ttgaagggca acttaaaggg
    40681 attgagcaat tgaaaaaaca cggaattgaa ggtgtagttg ttatcggtgg tgacggatct
    40741 taccacggcg ctatgcgttt gactgaacat ggcttcccag ctattggtct tccaggtaca
    40801 atcgataacg atatcgttgg tactgacttt acaatcggtt ttgacacagc ggttactact
    40861 gccatggacg ctatcgataa gattcgtgat acatcatcaa gtcaccgtcg tacttttgta
    40921 atcgaagtta tgggacgtaa cgctggtgat atcgctcttt gggctggtat tgcaactggt
    40981 gctgatgaaa tcatcatccc tgaagcaggc ttcaagatgg aagatatcgt agcaagcatc
    41041 aaagctggtt atgaatgtgg taaaaaacac aatatcatcg tcttagctga aggtgtgatg
    41101 tcagcggctg aatttggtca aaaacttaaa gaagctggag atacaagcga ccttcgtgta
    41161 acagaacttg gacatattca acgtggtggt tctccaactg cgcgtgaccg tgttttggcg
    41221 tcacgtatgg gtgcacatgc tgttaaactt cttaaagaag gtatcggtgg tgttgcggtt
    41281 ggtattcgta acgaaaaaat ggttgaaaat ccaattcttg gtactgcaga agaaggggca
    41341 ttgtttagcc ttactgcaga aggtaagatt gtggttaaca acccacacaa agccgatatt
    41401 gagctatcta gcttgaataa gagcttgtca taatttacaa tttagttaat aagaccaaaa
    41461 aggtcatata tataaaggag tcacaaaaat catgaacaaa cgtgtaaaaa tcgttgcaac
    41521 tttgggtcct gcggtagaaa tccgtggtgg taaaaaattc ggtgaggacg gatactgggg
    41581 tgaaaaactt gatgttgaag cttcagctaa aaacattgct aaattgattg aagctggtgc
    41641 taacacattc cgattcaact tctcacacgg cgaccaccaa gaacaaggtg agcgtatggc
    41701 aactgttaaa cttgcggaaa aaattgcagg taaaaaagtt ggtttccttc ttgatacaaa
    41761 aggacctgaa atccgtacag aattgttcga aggtgaagct aaagaatatt catacaaaac
    41821 tggtgaaaaa attcgtgttg caactaaaca aggaatcaaa tcaactcgtg aagtgattgc
    41881 gttgaacgtt gctggtgctc ttgatatcta tgatgatgtt gaagttggtc gtcaagtttt
    41941 ggttgacgat ggtaaacttg gtcttcgtgt ggttgctaaa gatgatgcaa ctcgtgaatt
    42001 tgaagttgaa gttgaaaacg atggtatcat cgctaaacaa aaaggtgtga acatccctaa
    42061 cactaaaatt cctttcccag ctcttgctga acgcgataac gacgatatcc gtttcggtct
    42121 tgaacaaggt atcaacttca tcgcaatttc attcgtacgt actgcaaaag atgtgaacga
    42181 agttcgtgca atctgtgaag aaactggaaa cggacatgtt caattgttcg ctaaaatcga
    42241 aaaccaacaa ggtatcgata acttagacga aatcatcgaa gcagctgatg gtattatgat
    42301 tgctcgtggt gatatgggta tcgaagtacc gttcgaaatg gttccagttt atcaaaaaat
    42361 gattatcaag aaagtcaatg ctgcaggtaa agttgttatc actgcaacaa acatgcttga
    42421 aacaatgact gaaaaaccac gtgcaactcg ttcagaagta tcagacgtat tcaacgctgt
    42481 tatcgacgga actgacgcta caatgctgtc aggcgagtct gcaaacggta aatacccact
    42541 cgagtcagta actacaatgg ctacaatcga caagaacgct caagctcttc ttaatgaata
    42601 cggacgtctt gattcagatt catttgagcg taactctaag acagaagtaa tggcttctgc
    42661 tgttaaagat gctactagct caatggatat caaattggtt gtaactctta ctaagacagg
    42721 tcatactgca cgtttgattt ctaaataccg tccaaatgct gacatcttag cattgacatt
    42781 tgacgaattg acagaacgtg gcttgatgtt gaactggggt gttatcccaa tgttgacaga
    42841 tgctccatct tcaactgacg atatgttcga aatcgctgaa cgtaaagcgg tagaagcagg
    42901 tctcgttgag tcaggcgatg atatcgttat cgttgctggt gtgccagtag gagaagctgt
    42961 tcgcacaaac acaatgcgta tccgcacagt acgttaagaa aaatataaaa acctatcata
    43021 tccagctttc tagcctgtat gatgggctct ttttttgtcc agggggcaaa aagggggcaa
    43081 aactttcata atggatt
//
LOCUS       DBEROT010000014        41658 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.14, whole genome shotgun sequence.
ACCESSION   DBEROT010000014 DBEROT010000000
VERSION     DBEROT010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 41658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.14"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..490
                     /locus_tag="ACL8CG_000893"
                     /pseudo
     CDS             1..490
                     /locus_tag="ACL8CG_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1123..2079)
                     /gene="lytA"
                     /locus_tag="ACL8CG_000894"
     CDS             complement(1123..2079)
                     /gene="lytA"
                     /locus_tag="ACL8CG_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGS1343512.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(2455..3825)
                     /locus_tag="ACL8CG_000895"
     CDS             complement(2455..3825)
                     /locus_tag="ACL8CG_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS1343513.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKQPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(4132..5298)
                     /gene="recA"
                     /locus_tag="ACL8CG_000896"
     CDS             complement(4132..5298)
                     /gene="recA"
                     /locus_tag="ACL8CG_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGS1343514.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(5353..6609)
                     /locus_tag="ACL8CG_000897"
     CDS             complement(5353..6609)
                     /locus_tag="ACL8CG_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGS1343515.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(6694..7710)
                     /locus_tag="ACL8CG_000898"
     CDS             complement(6694..7710)
                     /locus_tag="ACL8CG_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGS1343516.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(7718..8236)
                     /locus_tag="ACL8CG_000899"
     CDS             complement(7718..8236)
                     /locus_tag="ACL8CG_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS1343517.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVCHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            complement(8226..8669)
                     /gene="tsaE"
                     /locus_tag="ACL8CG_000900"
     CDS             complement(8226..8669)
                     /gene="tsaE"
                     /locus_tag="ACL8CG_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGS1343518.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(8755..9375)
                     /locus_tag="ACL8CG_000901"
     CDS             complement(8755..9375)
                     /locus_tag="ACL8CG_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343519.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(9758..10621)
                     /locus_tag="ACL8CG_000902"
     CDS             complement(9758..10621)
                     /locus_tag="ACL8CG_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1343520.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            10813..10983
                     /locus_tag="ACL8CG_000903"
     CDS             10813..10983
                     /locus_tag="ACL8CG_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGS1343521.1"
                     /translation="MRKKRGIKKLVTFALLGVFMFSNTIPYQQFIQKNKQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            11086..11310
                     /gene="pneA1"
                     /locus_tag="ACL8CG_000904"
     CDS             11086..11310
                     /gene="pneA1"
                     /locus_tag="ACL8CG_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HGS1343522.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            11317..11505
                     /gene="pneA2"
                     /locus_tag="ACL8CG_000905"
     CDS             11317..11505
                     /gene="pneA2"
                     /locus_tag="ACL8CG_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HGS1343523.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            11621..14611
                     /gene="lanM"
                     /locus_tag="ACL8CG_000906"
     CDS             11621..14611
                     /gene="lanM"
                     /locus_tag="ACL8CG_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="HGS1343524.1"
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSII
                     SEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKH
                     PQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPW
                     IVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESC
                     LRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKI
                     VYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLP
                     EYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDT
                     LFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKI
                     DFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTR
                     VLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDI
                     PIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSF
                     DQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGS
                     KWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGL
                     TGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINT
                     LVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKV
                     TRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGS
                     MAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIA
                     YTFLRYIALNQNDKKIVIPSLLEI"
     gene            14961..15665
                     /locus_tag="ACL8CG_000907"
     CDS             14961..15665
                     /locus_tag="ACL8CG_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGS1343525.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            15646..16575
                     /locus_tag="ACL8CG_000908"
     CDS             15646..16575
                     /locus_tag="ACL8CG_000908"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HGS1343526.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            16572..18680
                     /locus_tag="ACL8CG_000909"
     CDS             16572..18680
                     /locus_tag="ACL8CG_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGS1343527.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            18704..20443
                     /locus_tag="ACL8CG_000910"
     CDS             18704..20443
                     /locus_tag="ACL8CG_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS1343528.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            20494..21261
                     /locus_tag="ACL8CG_000911"
     CDS             20494..21261
                     /locus_tag="ACL8CG_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGS1343529.1"
                     /translation="MSQKLNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQLTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     ILVAFLVSLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            21263..21895
                     /locus_tag="ACL8CG_000912"
     CDS             21263..21895
                     /locus_tag="ACL8CG_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343530.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLESYDGMIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKVILKNPPLILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            22036..22314
                     /locus_tag="ACL8CG_000913"
     CDS             22036..22314
                     /locus_tag="ACL8CG_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HGS1343531.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(22823..23236)
                     /gene="ndk"
                     /locus_tag="ACL8CG_000914"
     CDS             complement(22823..23236)
                     /gene="ndk"
                     /locus_tag="ACL8CG_000914"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGS1343532.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(23347..27024)
                     /gene="rpoC"
                     /locus_tag="ACL8CG_000915"
     CDS             complement(23347..27024)
                     /gene="rpoC"
                     /locus_tag="ACL8CG_000915"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGS1343533.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYIHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLLYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(27057..30668)
                     /gene="rpoB"
                     /locus_tag="ACL8CG_000916"
     CDS             complement(27057..30668)
                     /gene="rpoB"
                     /locus_tag="ACL8CG_000916"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS1343534.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            31084..31154
                     /locus_tag="ACL8CG_000917"
     tRNA            31084..31154
                     /locus_tag="ACL8CG_000917"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31116..31118,aa:Cys,seq:gca)
     gene            complement(31352..32683)
                     /locus_tag="ACL8CG_000918"
     CDS             complement(31352..32683)
                     /locus_tag="ACL8CG_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGS1343535.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(32974..33798)
                     /gene="endA"
                     /locus_tag="ACL8CG_000919"
     CDS             complement(32974..33798)
                     /gene="endA"
                     /locus_tag="ACL8CG_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGS1343536.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(33837..34025)
                     /locus_tag="ACL8CG_000920"
     CDS             complement(33837..34025)
                     /locus_tag="ACL8CG_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS1343537.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(34018..35301)
                     /gene="murA"
                     /locus_tag="ACL8CG_000921"
     CDS             complement(34018..35301)
                     /gene="murA"
                     /locus_tag="ACL8CG_000921"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS1343538.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKVSQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(35325..35555)
                     /locus_tag="ACL8CG_000922"
     CDS             complement(35325..35555)
                     /locus_tag="ACL8CG_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGS1343539.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(35613..36650)
                     /locus_tag="ACL8CG_000923"
     CDS             complement(35613..36650)
                     /locus_tag="ACL8CG_000923"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGS1343540.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(36634..37122)
                     /gene="coaD"
                     /locus_tag="ACL8CG_000924"
     CDS             complement(36634..37122)
                     /gene="coaD"
                     /locus_tag="ACL8CG_000924"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGS1343541.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(37112..37651)
                     /gene="rsmD"
                     /locus_tag="ACL8CG_000925"
     CDS             complement(37112..37651)
                     /gene="rsmD"
                     /locus_tag="ACL8CG_000925"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGS1343542.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(37716..38708)
                     /gene="asnA"
                     /locus_tag="ACL8CG_000926"
     CDS             complement(37716..38708)
                     /gene="asnA"
                     /locus_tag="ACL8CG_000926"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGS1343543.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(38820..39503)
                     /locus_tag="ACL8CG_000927"
     CDS             complement(38820..39503)
                     /locus_tag="ACL8CG_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGS1343544.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(39559..40299)
                     /locus_tag="ACL8CG_000928"
     CDS             complement(39559..40299)
                     /locus_tag="ACL8CG_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGS1343545.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFYLS"
     gene            40333..40611
                     /locus_tag="ACL8CG_000929"
     CDS             40333..40611
                     /locus_tag="ACL8CG_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGS1343546.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYYDFKIAN"
     gene            40689..41615
                     /gene="yidC"
                     /locus_tag="ACL8CG_000930"
     CDS             40689..41615
                     /gene="yidC"
                     /locus_tag="ACL8CG_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS1343547.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
BASE COUNT        12937 a         8300 c         7687 g        12734 t
ORIGIN      
        1 ctcagttctg aggacacggt aatgattgat gcgacggaag tacaaatcaa tcgccctaaa
       61 aaaacaatta gcgaatgatt ctggtaaaaa gaaatgctac gctatgaagg ctcaagcgat
      121 tgtcacaagt caaggaagaa ttatttcttt ggatatcact gtgaactatt gtcatgatat
      181 gaagttgttc aaaatgagtc gcggaaatat cggacaagct ggtaaaatct tggctgacag
      241 tggttatcaa gggctcatga agatatatcc tcaagcacaa actccacgta aatccagcaa
      301 actcaagcca ctaacagttg aagataaagc ctgtaaccat gcgctatcca aggagagaag
      361 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgatttcaa caacctatcg
      421 aaatcatcgt aaacgcttcg gattacgaat gaatttgagt gctggtatta tcaatcatga
      481 actaggattt tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt
      541 gagacagcag ttatgatata tttatccatt cacaacatct tctgtaccaa tactacaata
      601 ttggtacatt ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat
      661 agtaattccc ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta
      721 gcctcagcaa aggactatga gcagcatttc ctagccaata ggacgctcca aatcacctat
      781 tctaaatcca tcactagctt ggtcagtaag atacagactg caaggcaaga ctgacgtggt
      841 tgatgagatt ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt
      901 taactatagt agattgaaac tagaatagta cacttctgct tctaaaacat tgttagaaat
      961 cgatttgact gtcctgatca atttgtcctg ttctcgtttc attctactat actaaaaaac
     1021 cacctgaaac aaatcaagtg actagaggat aaaaacgcat actattaagc tttttcaaga
     1081 cctaataata tgcgctgttc tgatttgaaa gacattccat tattatttta ctgtaatcaa
     1141 gccatctggc tctactgtga attctggctt gtctgccagt gttccgtctg gtttgaggta
     1201 gtaccagcct gttccgtccg ctgactggat aaaggcattt gataccatgg cgccttcttt
     1261 agcgtctaag tagtaccaag tgtccttgta cttgacccag cctgtcttca tggcaccttc
     1321 ttcgttgaaa tagtaccact tatcagcgat tttcttccag cctgtagcca tttcgcctga
     1381 gttgtcgaac cagtaccagt tgccgtctgt gtgcttcctc cagcggtctg caagcatata
     1441 gcctgaactg tcaaagtagt accaagtgcc attgattttc tcaaacttgt cttttggata
     1501 agagccgtct gagtgtacgt accagtagcc agtgtcattc ttctgccagc ctgtttcaat
     1561 cgtcaagccg ttctcaatat catgcttaaa ctgctcacgg ctaatgcccc attttgccaa
     1621 gtaagggtat ggatccacat ggtctgagtg gttgtttggt tggttattcg tgcaatactc
     1681 gtgcgtttta attccagcta aactccctgt atcaagcgtt ttcggcaaac ctgcttcatc
     1741 tgctagattg cgtaagagtt cgatataaag gcggtagtcc gtcatgaact cttctttagt
     1801 tgaatggctt tcaatcagtt caaccgctgc ataggtctca gcattccaac cgcccccaac
     1861 gtcccaggca ccattatcaa caggtcctac ctgcatgatg caaccgttcc caacaatgtg
     1921 cgagaaaaaa cctaattctg ggtctttccg ccagtgataa tccgcttcat tctgtacggt
     1981 tgaatgcgga ttcccagttg agtgtgcgtg tacttgccta tatggttgca cgccgacttg
     2041 aggcaaatct gttcttaatt tactcacatt aatttccata ttctactcct tatcaattaa
     2101 aacaactcat tttttacaat ccagaaccag aaactccttt atttctacct tacaaagaag
     2161 acaattttag tcacgattag gcttgtagat agaacttcaa aacgcactat tttgacactg
     2221 taaataggac tgacaaggtc tgcattctat ctacaataac accccaaact aaaaagcttt
     2281 tcaaaagtat atttttacag tctctatatg tccttttcat aaatactata ctttattata
     2341 tcatataaaa gaagtcaaaa gtctgttaaa ctattttcaa caccaaacta aagaagagaa
     2401 cacaagtttt ttcgattttc actagaggaa atggatttta ttcagtaaat ccaactagga
     2461 ttgcactttg gttgccaaaa ttgcctttcc ttcttttatc aagggatgac ggaatagtga
     2521 gaagtacagt tgaactgtca tggcaaccca gataagaggt tcacaaagga taacaccctt
     2581 atatcctgcc caaggaataa tcaaaaccac aaaaacgatt tttccgatta gttcaataaa
     2641 gctagaaact agaggaagga tcttctgccc caagccctgc aagcaattgc gataaatcaa
     2701 caagaggctc aaaatgggat aaaaggctga actgatttgc agatagagac ttccattttc
     2761 tatcaagtaa ccatctgtcg aactagccaa gaaggaaacc aaggctggac tggcaaaaaa
     2821 gaggaaaata caaacaaaaa ctgcccagga tatacttaaa cgactgccga ttcgaagacc
     2881 ttgaacaatg cggtcaggtt gcttagctcc tagattctga gaagcaaagg tcgtcattga
     2941 tgcagaaata gcggtcatag gaagaagggc aaaggtcata atgcgtcgag ctgccgtctg
     3001 ggcactaata atcactgcac caaatgtatt aacagaagac tgtaaaatca cactgccgat
     3061 agatacaatt gaactcatca agcccatagc caaaccttgc tccaagagat ctgcgtacaa
     3121 gcttttgtcc catttgaaat gtttaaactg tggcaagagt tctggcacac ttttacgaat
     3181 ataataaaag cagagaaccg ctgataaacc ttgcgaaata atggtagcaa gtcctgcgga
     3241 ttgaactccc agatgcaatt gcgtaataaa atagagatcc agaaccacat taaccaaggc
     3301 agagaaaatc agaaatccca gggctgctag actgtcacca atagaccgca acaagcctgc
     3361 aaaaagatta taagcaaagc tgacacctac acaggtcaca atcatagaaa tatattgata
     3421 agattgagga agaatttctg caggagtatc taagtattgc aagagaggat acaagccaag
     3481 aaagcccagc aacataacta gaatgctcaa aagagcacct aaaatccaag tagctgctac
     3541 tgcttccttg attttagtga aattccgagc cccataataa cgagcaatga caatccccat
     3601 gccattgcca acaccaagtg taaaacctac aatcaggtca aaaatcgctg tcgtcgctcc
     3661 tactgcagcc aaggattctt gaccaagaaa tcgtccaaca atcaagacat cagcagtgtt
     3721 atagagctgt tgaaaaatat ttgatagcaa aattggaaag gtgaagctta agagcgaggg
     3781 aagaatcgga ccatgtatca ggtccactgt tcgtttttta ttcataaagc tattatatca
     3841 gctttccaga ggagcgacaa gaaacagcaa acttatatat agcggaatga aataaggaaa
     3901 gtcaaatcga tttttaacaa tgttttagaa gtagatatgt actattctag tttcgatcta
     3961 ttatagttgg ttgagtttgg aatagtacgc tgtagctgct aaaacatttc tagaaattaa
     4021 tttgactttc ctaatagagt tgttcatatc ttatttcaag ctactatata taatctaaaa
     4081 acttgaatca aaaatcgaaa aagtagcgga tttctccact gctttaacag cttattcttc
     4141 aatttcgatt tcaagttcat cgcctaagtc aagcgtaact tcttcattca ctgcttcttc
     4201 tttctttggc tcatcttttt tgttttcagt atcttgttct gaaacttctt ctccatcaat
     4261 caagccaaat ttagaacgga cttgcttatc aatttcatca aagatttctg ggtgctctgc
     4321 caagtatttc ttagcattct cagaaccttg cccaattttt tcatctttgt aagaatacca
     4381 agcccctgct tttttgataa tatccaaatc gcttgcaatc ttcaaaagct caccagtctt
     4441 agaaattcct tctccgtaca taatttcaac tacggcttcc ttaaacggtg gagctacctt
     4501 attttttaca accttaatct tagtttcttt accgacattg gtttcttttt ggtcaccagt
     4561 tcccttaatt tgtgtattac cacgaacatc caagcggact gaagcataga atttcaaagc
     4621 acgtccgccc ggtgttgttt ctggatttcc aaacatcact ccaacttttt cacgcaattg
     4681 gttgataaaa atggcaattg ttttggtttt attgatagag gcgccaagtt tacgcatggc
     4741 ctggctcatc atacgagcct gcaaaccaac atggctatct ccgatatctc catcaatttc
     4801 cgcacgagga acaagggcag caactgagtc gactacgaca agatcaactg cacctgagtc
     4861 aatcaatttt cccgcaatct caagaccttg ctctcctgag tctggttgag acaagagtaa
     4921 ttcgtcaata ttgacaccaa gggccgcagc ataagctgga tcaagggcat gttccgcatc
     4981 gataaaggca gcaatcccac cttctttttg cgcttgtgca actgcatgaa gggcaaccgt
     5041 tgtcttacca gatgactctg ggccatagat ttcgatgata cgtcccttag gataaccacc
     5101 tgagccaagg gcaatgtcaa gagctaaaga acctgagctc atcacttgca ccttttgctc
     5161 cgcacgttca cccaaacgca tgattgatcc tttaccaaag tctttctcaa tcaatttaag
     5221 agcatcattc aaggcctttt cacgttctgc cccaaatttt tttgaaattt cttctaattt
     5281 ttttggtttt ttcgccattc tattctccta cattctaatg atcctcagac ctatctacta
     5341 ttatatcaaa agttagtcac ttaataaagc cttgcgaact aggttaaagg catgcataac
     5401 cgcaatatga cgtacatctg ctcggcttct gcctccaata ttaaccttga taacctcagt
     5461 tccttgctct tgcgccaagc ctatgaagac tgtcccaact gggtgtcctt ctaggctatc
     5521 tggtcctgcc actccggtca aactaattcc aaaatcagac tgggtcttgc ttcgtgcctg
     5581 ctcagccatc ttctgagctg taaattcaga caccacacca tgttcttcca aattcttggc
     5641 aggaatatcc aacatccttg atttttcctc caagctatag gtcacaaaac cacccttaaa
     5701 tatacttgaa gctccagaaa aattcgccac ggtagcttgg aaaagacctg ccgttaaact
     5761 ctctgcagcc gcgatggttt tcccttgcct tttcagttct tctaccacaa tgctggctaa
     5821 actagtttct tccccataac catagcaaaa gtctcgtaaa gaaattcctt cgaaagtctg
     5881 gcagtccaag atttgatttt ccaagatatc cagcgcttga ttcgcctctt cttgactgct
     5941 agcctttgtt gacagacgta gagtgacttc tcctgtcttg gcataagggg ccaaggtagg
     6001 atcgatctga ttatcaatta aatcagccaa aatcgtaacc aactggctct cgccaatccc
     6061 aaagaaacga agaactcggg aatacagctt gctccctgtc atcaacttgg gtagaagttg
     6121 gtttaagacc atgggtttca attcacttgg cggacctgga aggacgacat aggtcactcc
     6181 gtctacttct aattttcctc caacagccag tcctgtttcg tttggcagtg gaatcgctcc
     6241 ttctacaatt tgagcttgtc tttcgttatt cggtgttcgg gcatagtctg gtcgcagggc
     6301 aaaaaagata tccaacttct cctgagcctg aggatcaaag actaatgctt tccctaaaaa
     6361 tttagctagg gtttgtttgg ttaggtcgtc ctcagttggc cccaaaccgc ctgtcaaaat
     6421 caccagactg ctacgttgac tggcaatctc aagcaaagac aagagacgaa cttcattgtc
     6481 tcctacagcc gtctgaaaat atacatctac cccaatctca gctagttttt ccgacaaaaa
     6541 ctgggcattg gtgttgacaa tctgtcctgt caaaatctct gttccaacag caatgatttc
     6601 tgctttcatg tttcctccta cctatctatt cgtatttttt tgaaaaaatc gcaggaattt
     6661 tcctacgatt gattttttta tttgtatcaa aagttaatta tcttcatcac caacaggtgc
     6721 tctgccaaat aaatcttcaa ataaaaccgc attggtttca agctgagtaa cttcttcttg
     6781 tcccaaagaa cgtcggagta tattttgcat ttccaacata tgtgctctcg aaacaatctg
     6841 gtaagaaaca ccttgaagta tctctccttc accctgcaac tgctgagttt caatggtttt
     6901 aaatgaatct ttatagccta gcaagttagg gatacttttt gcagacaaat caatattggt
     6961 ctgcatattg tcactcaaag cttttagaat ctcttgataa tgaccaacgc tatttaaact
     7021 gagagctttt tccatgactt tttgaataac ttcacgttga cgtttttgac gaccataatc
     7081 cccctcagga tcttggtaac gcattcgtgc atagactagg gcttcttctc ccccaatatg
     7141 ttgctcccca acaccgatag aaatagtatt aaattcttct tggtcactga tagaaattgg
     7201 gaaacctagg atattattga ctgtaatacc tcctactgca tccactagtt tttgcaaccc
     7261 tctcatattg accatcacat agcgatcaat atggatattc atcatttttt gaatggtttc
     7321 tatagcaagc tctgctccac catctgcata tgctgagttc agtttcgctt catgagcctg
     7381 accattccct gattcaatgc gcgtcagaat atcccgctct aaactcatca ttgttgtttt
     7441 tttcgtttta ggattcactg tcatcaagat catactatca cttctaccga cccaagtttc
     7501 agttcgttca gcatttccgg tgtccactcc cattaacaga atggttagag gttcagtcgc
     7561 ttcaataacc ttggtttctt cgccgatttt tttataggtt ttagctaagg tttctgtccc
     7621 ttgttgataa atagtataag caaaaacacc tactcctact acagttacag aaagtaaagc
     7681 tagcaccatt ccaataattt ttttaaccat atttctacta atctatcagt ttacccatca
     7741 agtaaacatc gataaatttc ccttcttcta tatatgcccc acgctcttgg ctaccttcaa
     7801 tgacaaagcc atgcttttga taaagatgga ctgctgcttg attacgagtt tggacagtca
     7861 gttggagacg acgcagaatg ccacttgctt gtgcccactc tatcgcttct tctagcaaca
     7921 aacttcccaa gccattattc caatatcttt ttccaatcac aatgaagaga tctccaatat
     7981 gacagactct cttacgctgg tcagctgtaa tatttacaat accagcaatt ttgccattta
     8041 agaatgcaag taaggttatc tgattgtccg aactagcttg cttgttgagg aatatttcca
     8101 tctcctcact agtcaagaga ataccatctc cgtctaggct ggtaaagtct gtctccaaac
     8161 tcacacgatt taaaaaggcc actaattcag ctgcatcttt gggctctgct tccctaatga
     8221 gcaattcata ctccatattg aagctcctct aacaatttct cagcacgcaa accctttgcc
     8281 tgaaaattta aacggcgtcc atctgcttct tttagaattt ccaattctaa ataagcatct
     8341 ggcaaggcat ctcctaagag atttccccac tcaataacag tcacgccgcc accaaagata
     8401 aactcatcca agtcgataga atcagcatct ccttcaatac gataaacatc taggtgataa
     8461 agtggaagtc gaccttcata ctctctcacg atagtatagg taggactttt aatcatttga
     8521 gaaatctgta atccttttgc aagtccttta gtaaaggtcg ttttacctgc acccagttct
     8581 ccagttaaga ttaaaacatc attctttgct aatagatggc ccaaacgctc ccctaaggct
     8641 tgcaactctt cttcattttt tgtgtacata ctcttattat accaaaaact tttcttttgt
     8701 gtctattttc ctactaaact tatcatcata acatccataa aaaacaggct ttctctaaaa
     8761 gaaaatgagc gtaacaatga ccaatacaag atctcggaaa atatgaccat aaaaggaaac
     8821 ttccttctta accgaatttg ggacaagata ggctgcaaaa aacaagccca atccaatata
     8881 aatcagaagt gagacaatgg tcattggatt tcttaagaaa agaagtgttg ctaaaatagt
     8941 caccaacact gtcttttttc tgtctagcat agcaagaaaa tcgcgcacgt attttttcaa
     9001 gggtaaaaaa atcagcaaat ctagcccaaa taggaaaaag aaggatggca ataaaaagtc
     9061 aactaattct tgctgcagcg tatttttgat gaacaagtta tctgacaaaa caagaacagc
     9121 tcctaacaaa ttaattaaga gtaacatact gtaaaaaagc ttcaccgact tcttactggc
     9181 taggacacta tggacttctt gcttacgggt ataaagataa tttactccag cacagattcc
     9241 tgaaacgaaa accatgcttc cgatgaaaaa agctgtactt tgtttaaagg acaagatgca
     9301 ttccttccat aggaaacagc tactcaaact gatttgaatt aaagctaaca aaaataagat
     9361 tctcattgat ttcatcttct ctctcccttc ctaccaatca ttatactagg agaaaagaga
     9421 gaactgtttc taatcttctc aaatgtctct ttaagacgct aaacaaacac tagagactaa
     9481 tactcaatga aaatcaaaga tcaaactagg tagctagcca caggttgctc aaaacactgt
     9541 tttgagattg cagatagagc tgacgtgatt tgaagagatt ttcgaagaat ataaatttga
     9601 aatcatgaaa atccgtcaaa cgggtggttg ttttgtctcg cacctcacgg agcgagacgg
     9661 actcagagtc acataattat aaggctgata gtattaatct aactatcagc cttacaggtt
     9721 atttaacgtt tcagaaaaac tataatgtca agattaacta aacagtatct aattccttca
     9781 aataattttc tatcttcatc aacattaaag gattgttata aatcttacat aactctcttg
     9841 cttctatata ataatttttg acttgttctc tgtctagaaa tttggctcca gcatttccta
     9901 caagaataag tagaggagcc aattggtagc ttgtctgtct ttgtttacag agttcaatcg
     9961 tttcaagagc ttcttggatg gcttcattat atttttcctt tgatactagg tagtgagcgt
    10021 agttgtaacg aactctgatg tagccaaata aaaactcttg atggtccaaa ttttttgtct
    10081 gatacaactc tattaaatga gagtagtttg cctcatattc ttgttcacga cccactaagg
    10141 aatagaaatt agatagagta ttcaacgcct ttaaataaat cagagtattt gaagagactt
    10201 ttaataatat attttccaat gaagaaattg cctcacactt actgtcatat tgatagaagt
    10261 caataatagc tttaatccat tcaaggtaag ttcggtcttc taatgttaga aaagtgcttc
    10321 gttctacctc tattttataa agatattcta aatcgtcata atttctgtca tctaataggc
    10381 gagcagatag atgtttgaaa ttagagaggt tagacttaac ttcgatttgt tcattgaaaa
    10441 agtaatccaa agggacttca agtcgttgag agagtttgaa taacaagtct gcggagggaa
    10501 taaaatgacc tctttcaatt ttactaatct ggctttgttc acaaattcct tctgcaagag
    10561 tttgttggga gagtctcaac tcttttcttt tcaatctgaa tttctctgcg agtgtattca
    10621 ttaaagataa taaaccttcc tatttgctta atttcattat aaagttttta gttcaaaata
    10681 gcaagttaaa ggaataaata attctttatg gtaataaaca aaaaaaaaag ttaaaaatta
    10741 cataaaaata cttgactaaa taaaatatat ctgttagaat aaaaacaagg aaaaagaaag
    10801 gggtttcatt gcatgagaaa aaaacgtgga attaaaaaat tagttacatt tgcattgcta
    10861 ggtgttttta tgtttagtaa tacaattcct taccaacagt ttattcagaa gaataaacaa
    10921 ttggagattc gagtgcaatc gcaaaagaag tccaatggtc ttgatgttgg gaaggcggat
    10981 taaaacccga tattttgcac gagaatgaga gaattataat ttatctgaaa aaacgaaaaa
    11041 tatagagcaa cttatttaac tttttataag gaggagttat tacttatgac caactttaat
    11101 tcaaacgaaa aattttgtgg aaaaagttta aaatcattgt ctgctgatga aatgagttta
    11161 atttatggtg catctgatgg tgcagagcca cgttggacgc ctactcctat tattttgaaa
    11221 tcagctgcag ctagctcgaa agtatgcatt agtgcagctg tttctggtat tggggggcta
    11281 gttagctaca ataatgattg tttggggtaa attaaaatga aaaatgattt tgtaatcgga
    11341 aagagtttga aagaattatc tcttgaagaa atgcaattgg tttatggtgg cacagatggt
    11401 gctgacccta gatcaacaat tatatgttct gctacattaa gttttattgc atcatatttg
    11461 gggtcagctc agactcgttg tggcaaagac aacaagaaaa aataaaatat tcaattttaa
    11521 aaataaaagt tgctctttat tttcctctct cgtaactaat aattttgaga gaggtttttt
    11581 tttaaaacaa tagtaagtcg tataggtttg aggtaagtaa atgaaatata aaattaaaaa
    11641 tgtgcataaa acattgttta ttaaggaaag atatcaaata ttatctgaac gaaatgataa
    11701 ttccttaaat aacttttcat taaataattg gcgttctaca atgtcaatta tttctgaaaa
    11761 aacttttgaa gaaatgttga aattaaataa ttacaataaa aaaatatttt ctaacactgt
    11821 gaactatgat tataccgagg aacagataag actatattca gaatatgcca aaaattcgga
    11881 atggtataaa tttgcggagg gttcatttga aatatttaga aaacatcccc aaagaattaa
    11941 ttttaagaaa gatttttcta gaattttgga accctttatt attaatttgc ttaaattaat
    12001 caataattat ctagagaata aagaatacga gtggattgac aagaatggaa atattttttc
    12061 ctctctagta ttttatttag aagatttaat ctatccttgg attgttaaac ctttggtttt
    12121 agagataaat tcattgcgtg aaaaaggttt acttgaaggg gaatcggagc agcaacggta
    12181 caaatatttt ataacattgt ttgacaagga agagaatata ttaaattttt ataacaaata
    12241 tcccgtttta ctgaggcaaa tatcggagtc ttgtcttcgg ttctatactt attttataga
    12301 aattttatca aatttagaaa atgattttag tgtgctagaa gaagaattag ggctaagggg
    12361 gaaattaaat gatataaaat ttggaaaggg tgatacacac agccaaggaa aaactgtttt
    12421 gatactcttc tttgatgacg cgaaaattgt ttacaagcct aaaaatttaa taatcaataa
    12481 ctcactaaat actattgctg agtatatccg aaaggttgat gaaaaaatta ggataagaat
    12541 acctcgaact attgcttatt cggatcacag ctatgaagaa tttattgatt atctacctct
    12601 agagcaaaag aaaaaattac ctgaatatta ttataatttt ggtgtgcttt tagcatttat
    12661 atatttattt aatgggagtg atatacattt tgaaaattta atttcctatg gagatatgcc
    12721 tgtaataata gactttgaaa caatgttaca gcaacctcta tttgatgata aaactggtca
    12781 gagtttgctg gataccctgt ttcacagggt gactcgaact ttgcttcttc caacagaggg
    12841 agtaaaaagg gaggatggtc ttgatgttga gatgagtgct cttacaggaa attttaagaa
    12901 ggatgctttt aatggtcaag ttttaattaa tttaaatact gataaggtaa agtttgatat
    12961 tgggaaaatt gattttgaag gtgggaaaaa cctgcctgtt cgggatggtg atatagaatt
    13021 tgataagtat ataaaagatt tcaaaaaagg ttttagggat ttttatctga tatttgaaga
    13081 gttaaataaa acagaagaat ttaaaatgct attaaaagca aacttgtatg gtttaaagac
    13141 aagggtactt tttagagaca caaatagcta tgcttcagta ctatcttttt tatatcatcc
    13201 tgatttttat gaagaaatgt tagatagaga aaaagcattg gaaaatctct ggagcaataa
    13261 gttttctaat caaggtattg tagcaagcga atgtgaacaa atgaggttat tagatattcc
    13321 gattttttat acagatacaa atatcaatga aatctacgat gattttggaa atcattttat
    13381 ttccctacat caattttctg gatatgacta ttttatgaaa tatttaccta ataataattt
    13441 ggaaaattta gaaaagcaac ttgatatcat tgaaatttat tttccaagct ttgatcagcg
    13501 aaaaaaagga tataaattaa acttatctaa tagaaaaaaa ctcccaaatg aaagtttagt
    13561 tactattctg cataatgaag tagaaaatat tgcagactct ttggttatta ataatattta
    13621 tgacgaatat ccaatttgga gtatacctgt taattttaaa ggttctaaat ggtgtcttga
    13681 acaaacgggt aatgatatgt ataggggtag agctggaata ttactgttta tgtactatgt
    13741 aaaattattg aaagataaat catcatatac tcaactgtac aataaaatgt tatctgcaat
    13801 tccgccatct gtttctttat ctaagaccac atttggttta actggggata taggatattt
    13861 cattgttcta tccattatag aggattacga tacaaatact ctcgcatgct taaattatat
    13921 aaagagtgtt ttaactgagc ttgaaaagac tgattttgca agtgtttcaa acaagtctga
    13981 ctatattaat ggtcttctac ctttaattaa tacactggta agatattata ggagaggaat
    14041 agagaaggaa cgtgttctaa ggctagtatt aagtttaggt gatacgctat ataatgatgt
    14101 aagcgagaga gataatagta attttggata tagttttggc catggactat caggtgtaat
    14161 ttttacatta aaaaatattt ataaagtgac aagacttaaa aaatataaag aattaatttt
    14221 acaactagtt cctagggaga aaatcaaaat tcattctttg aagtggtgta gtggagaatt
    14281 tgggacatta gttaatcatc cccaaagtgt tccagaggga attgtagcta gtttagataa
    14341 tgatacattt tgccatggaa gtatggccat aataaatttt tacatcgact acatgaaaga
    14401 aatggatact agtatggaat tggagtcttt attgtgtagt gttgtaatga ataaatcaaa
    14461 agaaggagag tatcgtatcg tccaaacaag caatttccca gatttttctt tgtatacagg
    14521 tgtgactggt attgcttata cttttttaag gtatatcgca ctgaatcaga atgacaaaaa
    14581 gatagttatc ccctcattac ttgaaatcta gcttaattta tagttttgtt tctaaaatag
    14641 aggtgtccac tcattaagca atataaaaat accaagattg actagtttaa tatgtaattc
    14701 tataaaatat ttttaatagt gtagcttttc gttgagataa taatataata aagaaaggtt
    14761 ctattctaat tgctaaacgg cttgaggtat atgctactgt tatagaaatg attttaaact
    14821 aaaatcaaaa ttactccaaa aatagtattg attttggttt aatacaaaac atatgtaata
    14881 atgtgagtca acaaaagtct gtttttgtac catactatct tgaaaaatct actaaattca
    14941 aattgagagg atgaattaaa atgaataaaa tatttatata tgcaggagtg cgaaatcata
    15001 actctaagac tttagagtat actaagagac tttcaagtat catttctagt agaaataatg
    15061 ttgatatatc tttcaggaca cctttcaatt cagagctaga aatatctaat tctgattcag
    15121 aagagttgtt taagaaagga attgataggc aaagtaatgc tgatgatgga ggtgttataa
    15181 aaaaagagtt attagagtct gatattataa ttatctcttc tcctgtatat ttacaaaacg
    15241 tatctgtgga cacaaaaaac tttattgaaa ggattggggg gtggagccat ctttttcgat
    15301 tagctggaaa gtttgttgta acattagatg ttgctgagag taacggctct gataatgtgt
    15361 cagaatatct tagagatata ttttcatata tgggaggaca gatattacac caagtttcaa
    15421 ttaccaattc actcaaagat attgcagagg ctcagttgat ggaggcaact tataaaattg
    15481 aagatgtact tgaagggaaa attaagtaca aaacaacgga ttatcaagaa agagcttacc
    15541 agacattaaa attaatttta gaaaattatg attccgaaca ttttgagaag atgtattggg
    15601 agaaaaaacg cctttttgaa gctaatagtt tagaggaatg gtattatgtt gaaaatatta
    15661 aataactctg tcatatattt atgtttgatt ccgttattgt tcctattatt gataattttt
    15721 ccaaatgatt cattaatcta ttattttcga ttgattttaa tttcgttaat atcaattaca
    15781 ttacatgaac taggtcattt tttagtggga agatgtttat cttataaact agagatgctt
    15841 gctactccct ttttcttcta tttcagaaaa aaaatatatt tcaaatttcc agtgttatta
    15901 gcattcggtt attgtcaaat gagtaataga aacattacta atgaaaaaaa tagtgatagg
    15961 aatttggtgt tctacttctt tgggggaggt ggagctaacc taattgtcgc aatattagca
    16021 cttttgggat ttgtgccgta cgcatcagaa ttttttattt tgaatataat tctttttcta
    16081 gttacggtat gtttaccaat tgatggaaca gatggcaatg ctattagaga gatagttttg
    16141 tattcaaaag attcaaaaac atatcagaga ttctttgcga acagtctcta taataatcct
    16201 tatataacaa tcgacgattt tgcaaaatta acctctaaag aaaaatcttt tttttcaaaa
    16261 tttgaaaaat gtttgataaa cctttacttt gaagtgaaag gtgaagggtc agcatttaca
    16321 attgctaatc atgaagtttt tgattcaaat attcaggaaa atattatcca tgagtactat
    16381 aaattactac ataaatcttc tgattggatt attccacaga acttatcttt agaagaagtt
    16441 gtttttacct tgtcaaacta tatttactcg aaaaataata aatatttaga aaagattaag
    16501 tatctaaaga aattagtaga ttttagacaa gaagaaatta tcgactttat tttgaacaag
    16561 gaggaagtat tgtgaaaatt ccaatgatat atcaaatgga aaattcagaa tgtggattag
    16621 catgctgtgc catgatattg aactatttta aatatgagat ttctttaaat gaactacgtg
    16681 aaatctaccc atcatccaga tctggatatt ctctcctatc tataagtaaa gttttaggag
    16741 attttaatat aagttctcat gcttttaaag cttcggtaag agatttaaaa ccgctcagtt
    16801 tcccactcat ttgcttctgg gagagttctc attttattat tcttgaaaaa attagtaaaa
    16861 acaagtttta tattttagat cctgcaaaag gcaggcagag aatgtcaata agtgaatttg
    16921 aaaggcatta ttcaaatatc attttaacat ttaaaaagtt agatagcttt atgtctcgta
    16981 aagataataa gaagtcgcct gttttaaagt atttttttaa gtataggaat aagctaggga
    17041 ttttattttt tgtaacagca ttattgtatg taatacaatc attagtacct atagctaata
    17101 gatacataat tgacacgaat ttcaaggacg attcgtattc gtctagaatg ttatttacta
    17161 tattatttat atttactgtt tcattctcac taatgtattt attaagacag atatatgttg
    17221 catccttaaa atatataatg gataaagaga ttagctatga ttttatgaaa catttgatat
    17281 atttacctta cagtttttat gaaaaacgta ctttagggga tatacttttt agagctaact
    17341 ctattgttta tataagagaa atactatcaa ataattttat agcagctata cttgatttgt
    17401 taatgattgt ggtttatgct gtggttttat ttagcttttc taagtacatg gtaatctttt
    17461 taatatcact aagtctagct ctatctattg taatgtatcc aatcataaaa atctcaaaaa
    17521 atttaattga taaaaatata aaagaaaagg ttaatgttca aaatattact tccgaagtaa
    17581 tttctaaaaa tagtgatatt aagctaactg gagaagagga attttggatt aacaaatggg
    17641 ataattttaa tacaaaacag ctcatcatag gtcgaaaact tgatatacat ttatcaattg
    17701 ttagtagtat aacgaatgtt ttacaaatta ttctccctgt tttgaccctt attgtaggtg
    17761 taaatataaa aacattcgaa caattgacgt taggacaaat tgtagcaata agtacagtct
    17821 caccatactt tatttctcct ataatttctt taagtgataa ctatatacaa ttaatgttat
    17881 taaagggata ttttttaaga atagaggatg tgtttaatac taaatccgaa ttaattccag
    17941 aaagagtcag tcaagatata aaatttgata aaaaaataga attaaaagat atttggtata
    18001 aatatggatt atttgatgat tatgttttga aaggaataaa tgttactatt aaaaaaggag
    18061 aaactgttgc tattgttgga gaatcaggtt caggtaagag tacattagct aaaattttat
    18121 taggtttatt agaacctaat attggttcaa tagaagttga tggagtagaa aaagaagaaa
    18181 ttggtcaaac attgtataga aagatttttg gagcagtgtt acaaaattca accctaagtt
    18241 atggtacctt aagagagaat ttgacatttg gacactttgt ttcagatgaa gaattaatga
    18301 caaatctaaa ttcaattggt cttagcaatg tagttaaatc tttacctctt ggattagaga
    18361 caatcatcgc tgaagaaggt aataactttt ctggagggca gcagcaaatg atacttttag
    18421 ctcgttgtct tttgtcgaaa ccttcggtag ttgttttgga cgaagcaaca agtagtttag
    18481 ataatttatc tcaacaaatt acaacttctt acttaagtga aatcggtacc actaagattt
    18541 taattgccca tcgactagat actatcaagt ctgcagataa gatcttagta atgcataatg
    18601 gtgaaattgt agagattggg acccatagag aacttcttga actaggaggc atttataagc
    18661 aattgtattc aaataattag tttttgatta aaagggtaaa tttatgaaga ttatgaaaaa
    18721 aaaatattgg actttagcga tattattctt ttgtttgttc aataattctg ttactgctca
    18781 agaaatacct aaaaatcttg atggcaatat aactcacact cagactagcg aaagtttttc
    18841 tgaatctgat gaaaaacagg ttgactattc taataaaaat caagaagaag tagaccaaaa
    18901 taaatttcgt attcaaatcg ataagacaga attatttgta acaacagata aacatttaga
    18961 aaaaaactgt tgtaaattgg aacttgaacc acaaataaat aacgatattg ttaactctga
    19021 aagtaataat ttactaggcg aagataattt agataataaa attaaggaaa atgtttctca
    19081 tctagataat agaggaggaa atatagagca tgacaaagat aacttagaat cgtcgattgt
    19141 aagaaaatat gaatgggata tagataaagt tactggtgga ggcgaaagtt ataaattata
    19201 ttctaaaagt aattctaaag tttcaattgc tattttagat tcaggagtcg atttacaaaa
    19261 tactggatta ctgaaaaatc tttcaaatca ctcaaaaaac tatgtcccca ataaaggata
    19321 tttaggaaaa gaggagggag aggaaggaat aatatcagat attcaagata gattaggtca
    19381 tggtacggct gttgtagctc aaattgtagg ggatgacaat attaatggag taaatcctca
    19441 cgttaatatt aacgtctata gaatatttgg taagtcgtca gctagtccag attggattgt
    19501 aaaagcaatt tttgatgctg tagatgatgg caatgatatt atcaatctta gtactggaca
    19561 atatttaatg attgatggag aatatgagga cggaacaaat gattttgaaa catttttgaa
    19621 gtataaaaag gctattgatt acgcgaatca aaaaggagta attatagtag ctgcattagg
    19681 gaatgactcc ctaaatgtat caaatcagtc agatttattg aaacttatta gttcacgcaa
    19741 aaaagtaaga aaaccaggat tagtagttga tgttccaagt tatttctcat ctacaatttc
    19801 ggtcggaggc atagatcgct taggtaattt atcagatttt agcaataaag gggattctga
    19861 tgcaatatat gcgcctgcag gctcaacatt atctctttca gaattaggac ttaataactt
    19921 tattaatgca gaaaaatata aagaagattg gattttttcg gcaacactag gaggatatac
    19981 gtatctttat ggaaactcat ttgctgctcc taaagtttct ggtgcgattg caatgattat
    20041 tgataaatac aaattaaaag atcagcccta taattatatg tttgtaaaaa aaattctgga
    20101 agaaacatta ccagtaaaaa atggtataaa agtgttaaat ataccaaacg tattgagata
    20161 tgatttgaat atgttacaat tagaatataa aaatgaacaa agttgggata gtttcataga
    20221 taatgttaat ttaattgagt tggaagagag aattcaaact actattggaa ttaaacaaat
    20281 aaacacacac aatattatta ctattgcccg agaagggtac tctcaaaatt atttacctaa
    20341 cacttcagaa aatacatata attcattaca agtcagttta gttggagtat tactactttt
    20401 tataagtatg gtaaatattt tatgggctaa aaaaagtaaa tgaaaataaa atttggagcc
    20461 ctctgaaaaa gtaagtccta cagttcaact aaaatgagtc aaaagttgaa tcaccttgat
    20521 gtaggggagt ttgtcttatt gctgcctgaa cacctccgtt cagaggaaga acattataaa
    20581 tctgtttttg aagacgactt aaccagtcgc atgtctagtc aagatgaacg acagcaaatg
    20641 actgctacgg taggttattt agaatcaggt caggatcgtt ttgtgtataa tacgacccct
    20701 atttcttacc agcagttttt gaaagatcca atcatcattg ttataacacc ccaattaact
    20761 ggtccacagt ccattttgtt ttggatagac gcagtacaga actacgttct ctttaatcaa
    20821 ttgtctgatg cccaggagct tatccagaga caaggcattg aaaattgggt ctcagaaatg
    20881 caaacaggtt accacaacta catcacatta ttggataata tccagaggga acgttgggta
    20941 atgctagcag gagctgtgct tgggattgca acttcaatct tgttgtttaa cactatgaat
    21001 aggctctact ttgaagaatt tagacgtgcc atttttatca aacgcattgc aggtctcagg
    21061 ttcttagaaa tccatcgcac ttatctcttt gctcaactgg gtgtgttttt actgggattt
    21121 gttgcgagtg tatttcttca ggtagagata ctagttgctt tcttagtctc gttactcttt
    21181 actggtctat ctcttttaca gttacatgtc caaatgcaga aagaaaacaa gatgtccatg
    21241 cttgttttga agggaggtta atatgattga acttaaacag gtgagtaaat cttttggaga
    21301 acgagagtta ttttcgaatc tttcaatgac atttgaggct ggaaaagtct atgccttaat
    21361 tggttcaagt ggtagcggaa aaacaacctt gatgaacatg attgggaaat tagaatctta
    21421 tgatgggatg attttttacc gaggtaaaga cttggccaat tataaatcga gtgatttttt
    21481 ccgtcacgaa ttgggctacc tcttccagaa ctttggctta attgaaaacc aaagtattga
    21541 agaaaacctt aagctaggtc tcattggtca aaagttgagt cggtcggaac agcggttgag
    21601 gcagaagcag gctttagaac aggtcggcct ggcttatctt gacctagata agcgcatctt
    21661 tgagttatcg ggcggagaat cgcaacgggt tgccttggca aaagttatct taaagaatcc
    21721 accccttatt ctggcagatg agccaacagc ttcaatagac ccagcaacct ctcagttgat
    21781 tatggagatt ttgctatctc ttcgagatga taataggcta atcattatcg caacacataa
    21841 tccggcaatt tgggagatgg ctgatgaagt gttcacgatg gatcatctga aataaaaatc
    21901 cttgttttta attgcacgat gagttactga aatattatca tgaatcaata attggagtta
    21961 atttagaatt gtactttatt aatattgagg taactttttc ttgataaagg aggaaatagt
    22021 ggagaggaag ttagaatgaa aaaattcgac aattatatta ttgagaagcc ttgcgattct
    22081 aattcagata aactgcaaaa aatcttaata attgaaaatt tggtagatga tattttgcaa
    22141 tttcctctca gaatcaataa tagtgtagga gagattttcc tcctacaacc gtttcaaaag
    22201 aaaactatct ttattccatg ttattttgag gaagatattg tgaaagtcaa agatgatgat
    22261 aaagttgagt ggaatttgtt agaatttcaa aaatttagag catttttggc ttagtaatct
    22321 gtgttgaagg ctcaaaacct atggtaaaaa agtcgctttg aaaacgtatt gcctccaaag
    22381 atttagttaa ataatgattt aacacaaaaa gaaattattg aagttctgga aagatgttgt
    22441 ttcagtattg agaaaaggtg ggaaaaactt gcgattttca cagagaaagg aagaaaaagt
    22501 atagaaatat agtcaattga aacaagaaca ggacaaaaga accttttgtg ccatattttt
    22561 ctcctttcgc tttacaattg gcttgaacac ctttattgta tcgcgtttgg agtttttttg
    22621 gtataacctt cgacgcgcac ccgcatagcg ggtgtttttt tgtctcgcac ctaacggagc
    22681 gagacgaact aatagtcact taatcaaaaa acgcaccata tcaaaaacta aaaagtttga
    22741 tatcatgcgt catgtcttaa actaattgac tatactttct attcaaatga gcttttaacc
    22801 aattgattga gccaatccac tcttaaaacc aaagagcaat ttctcgctta gctgactctt
    22861 ctgaatctga accatgtaca acattttgga taacctcatt ttctccagca gcttttgcaa
    22921 agtcacctcg aatagtgcct ggtaaagctt cttctggacg agttgcaccc atcatggtcc
    22981 gccaagtttc gattactttg ggaccagaaa tgacacccac aagaactgga cctgaagtca
    23041 tgaattcacg aatcggtagg taaaaactct gaccaaccaa gtcctgatag tgctggtcaa
    23101 tcaactcttc tgaaacctgt gaacgaaact ccaatttttc gattgtaaat ccacgttgtt
    23161 cgatgcgctt taacacttca cccactagcc ctctttttac accatctggt ttgatgataa
    23221 agaatgtttg ttccataccc gtctcctttg tcagcttctt tcttttattt taccacattt
    23281 cgtggaaaaa tggagaaagt tttcagaaga gagaatgaga gaaccctcgg gttctctcat
    23341 tctctcttat tctactgttt cttccacagt ttcaacggca gtatccacaa ctacttctgt
    23401 tgtttcttca tttccttctt cctctactgg aggattaagg tattcttctt cgttgacagc
    23461 atgtggttca aggttacggt aacgggccat accagtacca gctgggatga tcttaccgat
    23521 gataacattt tctttaagtc caaggagatg gtctttctta ccacggatag ctgcgtcagt
    23581 aaggacacga gttgtttctt ggaaggaagc tgctgacaag aaactgtttg tttcaagtga
    23641 ggctttggta attcccataa ggactgggcg acctgtcgct ggaactccac ctgcgataag
    23701 gacatctttg ttggcatctg taaagtcatt gatatccatg agggtaccca tgagaagatc
    23761 tgtatcacct ggatccatga cacggacttt acggatcatt tgacgaacca ttacctcgat
    23821 gtgtttgtca ccgatttcta ccccttggct acggtaaact ttttgtactt caccgagaag
    23881 gtacgtttca actgacaaga catcacgaac tgcaaggaga cgttttggtt ggatagaacc
    23941 ttctgtcaga gcagcaccac gcgctacttg gcccccaact tcgacacgca tacgagctgt
    24001 aaatggaacg acatattcac cttcgccagt ttcaccctta acaaagactt tcttggtacg
    24061 agttgatgca tcttcttcga tagcagtaac ttgtccttta acctctgtga taaccgcttc
    24121 ccctttagga ttacgggctt caaagatttc ttggacacga ggaagaccct gagtgatatc
    24181 ggtatttgag gcaaccccac ctgtgtggaa ggtacgcatt gtaagctgtg taccaggttc
    24241 cccgatagat tgggcagcaa ttgtaccaac tgcttcacca acttcaaccg catcaccagt
    24301 cgccaagttg ataccgtaac agtgacggca gacaccgtga cgagtgttac atgtaaatac
    24361 agaacggata gtcacttctt ccacaccagc attgacaatt tcacgcgcct tgtcttctgt
    24421 aatcaattca tttggaccaa taatcactgc accagtttct ggatgtttaa cagttttctt
    24481 agtgtaacga ccgttgagac gctcttcgag agactcgatc atctcttttc cttctgcgat
    24541 agaacggatc aagagaccac ggtcagttcc acagtcgtcc tcacggatga taacgtcttg
    24601 ggcaacgtcg accaaacgac gagtcaagta acctgagtcg gctgtcttaa gggccgtatc
    24661 ggtcatacct ttacgagcac cgtgagttga gaagaacatt tccaataccg acaaaccttc
    24721 gcggaagttt gaaaggattg gcaattccat gatacgtcca ttcggagcag ccatcagacc
    24781 acgcataccg gcaagctgtg agaagtttga gatgttacca cgggctccag agtccatcat
    24841 cataacgatt gggttcttag gatcttggtt agcaatcaag cgtttctcaa gtttttcacg
    24901 ggcagcacgc cattcagctg taacagcatt gtaacgctcg tcgtctgtga tcataccacg
    24961 acggaattgt ttggtgattt gttcgacacg tttgtgtgat tcttcaatga tttcagtctt
    25021 gtcatcaacg actgggatat cggcaatacc cactgtcaat cctgcaagag ttgagtggtg
    25081 gtaaccgagg ttcttcatgc ggtcaagtag ggcagaagtt tctgtcgtac ggaaacgttt
    25141 gaagatttca gcgatgatat ttccaaggtt tttcttcttg aatggagggt tgagctcaag
    25201 attgctgata gcttccttga tatctccacc aagtggcaag aagtatttag ctggaacacc
    25261 ttctgtcaag ttggcattgt ttggttcttg caagtatagt agcccctctg gcatgatatc
    25321 gttgaagaga attttaccaa ctgttgtaag caagacctta tgtctttgct cttctgtcca
    25381 aggcttgttg aggctgtctg ttgcgatacc aacacgtgag tggaggtgaa tataaccatt
    25441 gcggtaagcc ataaccgctt cgtcacggtc tttgaagacc attccttcac cttcgcgacc
    25501 agcttcttcc atggtcaagt agtagttacc caaaaccatg tcctgagatg gagtaactac
    25561 cggtttccca tctttcgggt tcaagatgtg ctcagcagct agcatgagga tacgagcttc
    25621 tgcttgtgct tcttctgaaa gtggtacgtg gatggccatt tggtccccgt caaagtcagc
    25681 attgtaggct tcacagacaa gtgggtgcaa gcgaagagcc ttaccatcaa tcaagactgg
    25741 ctcgaaggct tggataccca aacggtgaag ggtcggtgcg cggttcaaaa gcactgggtg
    25801 ttctttaatc acttcttcaa ggatatccca gatacgctca tctccgcgtt ccaccaagcg
    25861 tttagctgct ttgacgtttt gcacgatatc acgggcaacg atttcacgca tgacaaatgg
    25921 tttaaagagt tcaatcgcca tttcacgcgg cacaccacat tggtacatct taagagttgg
    25981 accaacggcg ataacggaac gtcctgagaa gtcaacacgt ttaccgagca agttttgacg
    26041 gaagcgtccc tgtttacctt taagcatgtg gctcaatgat ttcaatggac ggctacctgg
    26101 tcctgtgatt ggacgaccac gacgaccatt gtcaatcaaa gcgtcaactg cttcttgaag
    26161 catacgcttc tcattttgaa cgatgatacc tggggcattt aactcaagca aacgagccaa
    26221 acggttgtta cggttgataa cacggcggta aaggtcattc aagtcagatg aggcaaaacg
    26281 gccaccatcc aactgcaaca ttggacgaag atctggtggg ataaccggaa ggatgttaag
    26341 aatcatccat tcaggtttgt ttccagactt gtaaaaggca tccaaaacat ccaaacgacg
    26401 gatggctttg acacgttttt gtccagtagc tgttttcaat tcttctttga gttcagcaat
    26461 ttctttttca agatctactt gcttcaaaag gtcttggatg gcttccgcac ccatcttggc
    26521 aacaaatgaa ccataaccat attcacgcaa gcgctctcgg tattcgcgct ctgtcatgat
    26581 agacttgtgc tcaagtggtg tatccttagg atcaatcacc acataagccg caaagtagat
    26641 aacttcctcg agggcacgag ggctcatatc aagggtcaag cccatacggc ttggaatccc
    26701 cttgaagtac cagatgtgag atacaggagc tttcaactcg atatgtccca tacgctcacg
    26761 acgaactttc gtacgcgtta cttcaacccc acagcggtca caaacaattc ctctgtaacg
    26821 aatgcgtttg tacttaccac aagcacattc ccagtctttt gtaggaccaa agatcacttc
    26881 atcaaagagt ccttcacgtt ctggtttcaa ggtacggtaa ttgattgttt caggtttttt
    26941 gacttctcca taagaccatg aacggacttt acttggagaa gctagggtga tttgcatact
    27001 tttaaaacga tttacatcaa ccactatttc ttccctttct attctaagtg aactgcttat
    27061 tcctgttcag cagcttcttc tgttgcttcc gcttttgttg ctttctcagc ttcttcagct
    27121 tcaaaggctg ctttagcctc ttgggctgct ttttcgcggg ctttttcaag gtcatctacg
    27181 tggatgacat cttcgtccat tccttcatcc aagtcgcgaa gttccacttc ttggtcatct
    27241 tcgtctagaa cacgcatgtc aagaccaaga gattgcaatt ctttgacaag aactcggaag
    27301 gattctggaa cacctggttt tggaattggt ttgccttttg taatagcttc ataggctttc
    27361 aaacgtccgt tgatatcgtc cgacttgtaa gtcaagattt cttgaaggac atttgacgca
    27421 ccgtaggctt caagagccca aacctccatc tcaccgaaac gttgtccacc aaactgagct
    27481 ttacctccga gtggttgttg ggtaacagtt gagtaaggtc cgactgaacg cgcgtgcaat
    27541 ttatcatcaa ccatgtggtg gagtttgatc atgtacatga ctccaacaga aacacggtta
    27601 tcaaatggtt cacctgtacg tccatcgtaa aggattgtct tggcatcgct atccatacct
    27661 gcttctttaa cagttgacca aagatcttca gaacttgctc catcaaagac tggtgtcgca
    27721 atgtgaatac caagagtacg agctgccata ccaaggtgaa gctccataac ctgaccgata
    27781 ttcatacgtg atggcacccc aagtgggttc aacatgatgt cgactggagt tccgtctgga
    27841 aggtaaggca tgtcttctac aggaacgata cgagagacaa cccctttgtt tccgtgacgt
    27901 ccggccattt tatctccgac cttaatctta cgtttttgag cgatgtaaac acgaaccaac
    27961 atgttaacac ctgattgcaa ctcatctcca tttacacgtg taaagatctt aacatcacga
    28021 acgacaccat cggcaccgtg tggtacacga agagaagtat cacgcacttc acgagacttg
    28081 tctccaaaga tagcgtgcaa gagacgttct tcagctgaaa gatctttctc acccttaggt
    28141 gttactttac ctacaagaat atcaccttct ttaacctcag caccaatacg gataatcccc
    28201 atttcgtcaa ggtctttgag ggcatcttca ccaacgtttg gaatttcgcg agtgatttct
    28261 tcaggcccaa gctttgtatc gcgcgtttct gattcgtatt cttcaaggtg aacagatgtg
    28321 tagacatcgt ccttcaccaa gcgttcgctc atgataacgg catcctcgaa gttgtaacct
    28381 tcccaagtca tgtaggcaac gattgggttt tgtccaagcg ccatttctcc attttccata
    28441 gaaggtccgt cagcgatgaa atcgcctttt tcaacgacat caccaacttt tacgagagtg
    28501 cgttggttgt aagcagtacc tgagtttgaa cgacggaatt tttggatgtg gtaaacatcc
    28561 aatgaaccat cttcacgacg aacttctacc ttgtcagcat ctgcgtaagt aactttacca
    28621 tcatactgag caatcacagc cgcaccagaa tcgtgggctg cttggtattc cataccagta
    28681 ccaacgtaag gtgcctgagg attaatcaat ggcacagcct gacgttgcat attggctccc
    28741 atgagggcac ggttggagtc atcgttttcc aagaaaggaa tacatgctgt cgcaacggca
    28801 actacctgtt ttggtgaaac gtccatgtag tcaacaatat tagctggata ctcttggttg
    28861 accccttggt gacgtcccat gacaatcttc tcagcaaagg ttccatcttc attcagacga
    28921 gagttagcct gagctacagt atattcatct tcttcatcag ctgtcaacca aacaatttcg
    28981 ttcgtgacaa cacctgtttc acggtcaacc ttacggtatg gtgtttgaac aaaaccatat
    29041 ttgttcaagt gtccgtaaga tgacaagtta ttgatcaaac cgatgttagg tccttcaggt
    29101 gtctcgattg gacacatacg accatagtga gtgtagtgca cgtcacgcac ttcatatccg
    29161 gcacggtcac gagtcaaacc accaggtcct aaggctgaca aacggcgttt gtgagacaac
    29221 tcagaaagcg ggttgtgttg gtccatgaac tgtgacaact gtgatgaacc aaagaattct
    29281 ttaactgcag ctgttacagg acgaatattg ataatttgtt gtggtgtcaa gacttcattg
    29341 tcctgaacag acatacgttc acggacatta cgttccatac gagaaagtcc caaacgtact
    29401 tggttggcaa gcaattcacc aaccgcacgg atacgacgat ttccaaggtg gtcgatatca
    29461 tctacacggc caagtccttc agccaagttg aggaagtagc tcatctcagc aaggatatct
    29521 gcaggagtca ccgtacgaac cttgtcatct gggttagcat taccaatgat cgttacgacg
    29581 cgatctggat cagttggagc aataaccttg aatttttgaa gaacaacagg ctcagtcaca
    29641 acggctgcat cgtttgggat gtagacaatc ttgttcaagt cgccatccaa atggctttca
    29701 atgctttcaa tcacgctacg agtcataatc gtaccagctt ctaccaagat ttctccagtt
    29761 tcagggtcta ccaatggctc tgcaatggtt tggttgagca aacgtgtttt aacattgagt
    29821 tttttattga ttttgtaacg accaactgct gccaagtcat aacgacgtgg gtcaaagaag
    29881 cgagctacaa gcaagctacg tgagctttca gccgtcttag gctcacctgg acgaaggcgt
    29941 tcgtaaattt ctttcaaggc ttcgtctgta cgagagtcca ttggattctt gtggatatct
    30001 ttttcaacag tgttgcgaac caattcgctg tctccaaaga tatcaaagat ttcatcatca
    30061 cctgagaaac caagagcacg aaccaaggtt gtaaatggaa tcttacgagt acggtcgata
    30121 cgagtgtagg tgatatcttt tgagtcgctt tcaagttcca accaagctcc acggttaggg
    30181 ataacagttg aaccatagcc caccttacca tttttgtcta ctttgtcgtt aaagtaaaca
    30241 cctggtgagc ggaccaactg agaaacgata atacgttcac caccattgat gatgaaagta
    30301 cccatttctg tcatgattgg gaaatcacca aagaaaactt cttgggtctt gatttcgcct
    30361 gtttctttat tgatcaaacg gaaggttaca aaaattggtg ctgagtagct agcatcgtgg
    30421 atacgagctt cttctagcgt gtattttggt tccttgattt catatccaac aaattccaac
    30481 tccattgtgt ctgtgaagtt tgaaattggc aatacatctt caaacacttc cttaagaccg
    30541 tggtctagga aagctttgaa tgagtcagtt tgaatttcaa tcaaatttgg taagtcaaga
    30601 acttctttga ttcttgaaaa actacgacgg gtacgatgtt tcccgtattg aacgtcatgt
    30661 cctgccaaga tgattctcct ttgtaaataa gttccaagcc ttgtcaatca ggcttttcta
    30721 atcgtcatat ggttgtaaac cccttatcac cgtgtcctct tgacgaattt tcagaatctt
    30781 taagcctctg ttacaaatgc tcataatctt gaaaaaaagc acaaaaagag cagctaaatc
    30841 tgactttttc agaagattta actgctgtga gccttgtctg gacaatattt cagacaaaac
    30901 ctacgacaaa tgattaccca tattataccc tatttagcta gatttttcaa ggggtttcag
    30961 taggtttttg gtaaattttt tcccatagaa aacttggcat cacattcgaa tcacgctatg
    31021 gtacaaaaaa ctgaaaaaac tattgactga aaatcatttt caaggtataa taataaacgt
    31081 taaggcggta tagccaagtg gtaaggcacg gctctgcaaa agcttgatcg tcggttcaaa
    31141 tccgtctacc gccttctata acttgattta tcaggtttca aatgaacaga aagcccaatt
    31201 tgaagggctt tttttatttt ccctcgaata aatacgtata actttaaaaa cttttggagc
    31261 gagtttgtgg cagagttctt tccatggcat aattcccttt tgaaatcaat tgaaaaaagc
    31321 ttcgtcacgc ctggtgacaa aagcctctag tttattctgt ttcttcttct atttcgactt
    31381 ctgtgatttg gacttttacc ttggtaacac gtccattctt cactttatca ttggttaaga
    31441 taaactgttt gttttggctg accaattcat agctgagttt ctcagtcgtt ggaatggttc
    31501 ccactcctgt caaataataa ccagcgatgg tatcaacgtc atcactttcc agctcaacat
    31561 caaagtaatt attgaaatca ttgagggtca tagttccttg aacaatgtag gtatcctcgc
    31621 caatctgatg aacatctatt gctgctttgt ccgtttcatc atcaatttca ccaacaattt
    31681 cctctaagag gtcttccaaa gtcactaaac cagccatacc accgtattca tccagcaaga
    31741 ttgccatttg tctttgggta tttcgcagtt cttttagcaa gtcatccaca aaaatagttt
    31801 caggtacaaa aagtggatct tgtaaaattc tcttccaaac aatattgtca aaaccgtcca
    31861 caaagcctgc cttaaggaga ctcttggtgt gaatgattcc aattacattg tccttatccc
    31921 catcataaac cgggatacga gaataatttt gttttaaaat actttggata atggcttgac
    31981 tatcatcctg aatatccacc ataaaggcat ctgttcgagg aaccataacc tctcgtgcca
    32041 tcagttcatc gagcgaaaag acaccttgta gcatctcaat ctcatcagca tccaatgttt
    32101 cttcactatt tgtcagcata taggcaattt catcacgggt cattttttca tccgcatcat
    32161 cgaatgacat aggagtcaaa tggctcaaga aattggtcga agcagctaaa agccaaacaa
    32221 aaggactgac tagttttccg atcccaatga taaccggcgc tgtacgaatt gccaaggcat
    32281 cctttagatt aagagcgatt ctcttaggat ataattcccc aaaaacgatg gaaatatagg
    32341 tcaaaaatgc caaggataga aaagttgcca cggcttgtgc tgtttcgcca ttcccaagcc
    32401 aagaggcaat cacacgtcct agagtatcag ttaaactcgc ccctgataag attgtaatca
    32461 gggtgattcc tacctgaatg gttgataaaa agtggttagg attttctagt accttcagca
    32521 ggcggatgta gcgtctgtct ccttcttccg ccttttgttc aactcgggca cgattaagag
    32581 aaaccatggc catttctgtg gctgagaaaa aggcatttaa taccgtcaag ataaacaata
    32641 aaacaaattg tagcaacaaa ttctgactac ttgggtcttc catagttctt ctcctaaaat
    32701 agtatcttat cccttattat atcacaaaat ttaatccaat acatattatt tttttcttag
    32761 cgtaacttcc atctctctcc caaaactgga agttaggcta agacggattt ccactgattt
    32821 cacgcgtttt tctcatacta aaagctaggt tgtgggaaac tggaagttag ttttagaagt
    32881 tactattttt tcttagtacc tgttctaacc ctgcttaaac tagtaaaaag aactcctaca
    32941 tccataagtg acataggagt ttaggcttat cttttactga gttacagtta cttctccagt
    33001 tcggtaatcc agttgaagtc ccttttgaac attgggaact agaacattga attccaattc
    33061 tccatccgaa gacttggctt caatctgtga agctgaggga actaaatcct cgtttgaagc
    33121 gtagtaaagg gttacacggt aacggacacg cttgttttgg tccaaggctt tacgcacctt
    33181 gctttcatag tagttttgac cagtcgaata ctcggcttgt gcctgatttg cccaggctgt
    33241 ctgaacagca atgtttttag gattgcttgt tgaggcatca aaaccatcca aaccaccgat
    33301 taaggcatag cctaacaaat gacctctatc gactgcatgg gtataagagc cctttagatt
    33361 cttgacctga tgccaacctg gaggagtcca agaagttgaa ccattcccag tttctttacg
    33421 attcttgtac tgacgagtgg ccttagacaa gagggcatta gctacggttg gaacagtttc
    33481 cttgcccact gtctttgttt tattgtcagc gtagggctta cttgaaacct tggcatctag
    33541 atttgtttta ttaccattga cgataaaagc acctgagcca ttccactcca gactcccctt
    33601 tatttgactc ttgactgcgt ctgttaagac actctctgcc aatgcttgac taggagcttc
    33661 agacgcttgt tttttctgac taagcttggt tttaggacta ttagctgtcg actgcatctg
    33721 cttgatataa tagctccctg tagacaaaag caataacact agcagtccga ttagtgtctg
    33781 tcttgttttt ttgttcatat ttctccttat ctttagaaaa aggctggttc tccagcctaa
    33841 tttcctgtaa atttatgaat caattcctgc cattttgctg gagacaggat agcccatgga
    33901 tcttgaccct tgcccaagat tccataacct accattaaac cgattcctag agccagagta
    33961 cctaaaatca gtactatgat gactaaaagt aaacgcttga ctacgtagct tgatttctta
    34021 ttcatcttca tcacttgcct caatccgctg aatcttagca cctagctgcg ccaacttctc
    34081 atggaaaccg tagtaacctc tatccaagtg aaccaattta ccgaccacag tttctccctg
    34141 tgctaccaaa cctgtcaaaa tcaaggccgc actggcacga aggtcagttg aaagaacttc
    34201 tgctccctgc aaaggctgtc caccaacaat acgagctgta tcacggataa tctcagaatg
    34261 caagcccatg cggcgcatct cttctaggtg ttggaaacga ttttcaaaaa ctgtctccac
    34321 catggttgat tcgccttttg caactgtcat caaggctgta aattgagcct gcatatctgt
    34381 tggaaatcct gggtggggca aggttttcac atgaacagct tttagatttt ccagttgaga
    34441 acgaacacga attccttcgt cttcttcaat tacttcaaca cccatttcaa gtaacttggc
    34501 aatcaaggga cggttgtgct cccagacagc gtctcgaatc aagacatcac caccagtcat
    34561 ggcagcagct accataaagg ttcctgcttc gatacggtcc tggactacat tgtgagtcgt
    34621 accatgaagt ttctcaacac cagtaatggt tatagtctct gtaccagcac ctttgacctt
    34681 ggctcccatt tcattaagga gaatggctaa gtcaacaatc tcaggctcac gcgcagcatt
    34741 ctcaatcact gtcaccccat cagccagagt cgctgccatc atcaagttct gcgttgcacc
    34801 aacacttgga aagtccatat agatatgagc gccatgcaag cgttctgcct tggcttcgat
    34861 gtaaccagct gtctgactaa ccttaacccc catagcttcc agacctttca aatgaagatc
    34921 aataggacgg ctaccaatcg tacaaccacc tggcatggat accttggcat gacccacacg
    34981 ggcaaggatt ggccctaata caacgatgga ggcgcgcatc ttgctgacat acttgtaagg
    35041 ggcttcctca gtgatgtcgc cagtagcatc caccttgaca agatgagctt cctcatcaaa
    35101 gtcaaccttg gcattcaaac caccaactac ctgattcata ataaagacat ccgacaaaat
    35161 cggaacattc tgcaagacgg tctttccttc acttgctaga atagtcgctg ccaacaaggg
    35221 taagactgca ttttttgctc cctcgatcgt cacgcttcct accagacgat tatcgccacc
    35281 ttgaaccaca attttatcca tactcgtttc ctttactctt gattttataa taatcctcta
    35341 agcgcttctt gccacaaatg atacaggcta ataaagaaag aactcaggat gtagcctatg
    35401 acaatgctaa aaaaggctac taataaacga acttttcttg tattctcagc tgtcactttt
    35461 aaaacctttt cccatctaac aagatccttt aaaaggtaaa aactcacata aataaagagc
    35521 atatgactac ttagagtgaa taataattga accatttgac tattatacca tcttctctgt
    35581 ttgtgcgcta gtttggaaac ttcactcaaa aattagggat tgtttttcaa gtaatcaatc
    35641 gcatcttgta gggttttaac gggcacgatt ttcatatccg tcttgattgt tttagccgct
    35701 tctagggctg tttggtagtt gtttttcgcg tccggatgcg ccttttgttc ttcttcgcta
    35761 acagggttat caggagcaaa gaaaatagca gcacctgccc tagccgaagc tacaaccttc
    35821 ttatcaatac ctccaatgtc tcccacatta ccatcgcggt caatggtacc tgtaccggca
    35881 acaatacgac cattacgaag atctgggtga gctatttgag tatagatagc tagactaaac
    35941 atgagaccag cacttggacc gccaatacca gctgttgaaa agctaattgg gacattgctg
    36001 attacctctg tacggtcaat caagccgatt ccaattccat ttttgccatt ttccaaggtg
    36061 ataatctttc cttctgcaga cttggtttgc ccatcctctt cataggtgac cttgacggag
    36121 tcccctaatt tttgagaact gacgtaatca atcaagtctt tggaactatc aaaggtctga
    36181 tcattgactg ctgtgactgt atcagagata ttgagaatcc ctttaaaggt tgaattatcc
    36241 gtcacattca aaacataaac tccaaagtac ttgagttcga tttccttacc agctgttttt
    36301 agtccttgat acttggccat attttgcgat gtttgcatgt agaattgatt gattcgcata
    36361 aattcaacat cggaagaacc acctgtagtc tcctgagcac tacgaatatc tgtaaaaggt
    36421 gtcaaccaag cataaatcat atgagctaaa gtagcatgtt gaacaccaac cgtaacgaat
    36481 tgataggcac cagcttcctt atcttctgtg tcatttactt taaggacttg gcgaatatct
    36541 tccgaaccac ctggaacctc tatatagtag ggcaaaggca ccacaaatgc caagaaggtc
    36601 acaatcaagg ccgcaatgac atacaaaggc catctaatct tttttttcat ttcttatttc
    36661 ctccaaaata ctctcgggaa catggcaggc aatatcctga ccaaacttca aaagctctcg
    36721 aacacctgat gaactgatat agagatgttc aggccggcta tgtaaataaa tagtctctat
    36781 atcagaagac agctgatgat tgtagtaatc aaaactagct tcatattgca aatccgccgc
    36841 attcctcaac ccccgtacta gaaaagtagc ccccagtctt tttgcaacat cgaccaccaa
    36901 tttatcatga gaagccacga cttcaacatt ttccaaatgt cccaaagcct tttctagccc
    36961 ccgtttacga ttttcaagag ggagaaatcc ttgtttgtgg ggattaaaaa aaatacccac
    37021 ataaagctta tcaaaaagtc tgctcgcccg ttcaatgata tccagatgcc catttgtcat
    37081 cggatcaaat gagcctgtga ataagccaat cttatctgac atagactgtc accttactaa
    37141 ttccataaat cttttccttc cagataccca gacaggcaat ttcttctgga agttcaacgg
    37201 ctttatccgt ctcgcacaca accataacat cttcagaaaa aagctctctc tcagccattt
    37261 tttcaatatc tgctacgatt tgttccttgg catagggagg gtctaagaaa acgaggtcaa
    37321 attccccaga tacctgttcc aatgcccttt ctgcatccat ctttaggagt tgaaattttc
    37381 caacttcctt ggtcatctgg atattttcag ccacgatggt ctgagcctta cggtctcgct
    37441 ccaccaaaac agcactggac atgccacgcg atactgcttc gatagataaa ccaccactac
    37501 ctgcataaag gtccaagact cgtcccactt caaagtaggg accaatcatg ttaaaaatgg
    37561 ctcccctaac cttatccgaa gtaggtcttg tcgtcttgcc ttctagtgtc ttgaggggac
    37621 gtcccccata gattcctgat acgattttca tactgtttat tataccaaat tatagacaaa
    37681 aagagaaaga aaaccgaacc ttgcggttcg attctctaca aaatattttc gtaagtatcg
    37741 cggacttctt gaggccaaac acttgtttgc acttctccga tgtgtctctt gcgaagtagg
    37801 aacatggcca tacgagattg tccaattcct ccaccgattg tcaatgggaa tagaccattc
    37861 aacaaagact tgtgccattc caattccaag cggtcttcat cacctgtaat ttccacctga
    37921 cgtctaagag tttcttcatc tacacgaatt cccatagaag acaactcaaa ggctccacct
    37981 aaagactcat tccagacaag aatatcacca tttagaccct tgtagccatt ctcagactcg
    38041 cttgtccagt catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc tggcaactcg
    38101 ccaccgatac caatcaaaaa gacggctcca aattctttac aaatcgcatt ttcacgttct
    38161 ttcggtgtca agtctgggta gcgttctacc aattcttctg tatggataaa ggtgatttgt
    38221 tttggcaaga tagactcgat gtcatagcgg gcttcaacag ctagctcagt caggcgaata
    38281 gccttataaa tcttctcaac tgtttctttt agataaacga tgttacgctt accatttggg
    38341 ataaccttct cccagtccca ctggtcaaca taaacagagt gggttgcatc caaggaatcc
    38401 tcatctggac gaagggcttt catgtggaca aagagaccct ctccttcacc aaagccaaaa
    38461 cgagccaagg tgtggcgttt ccatttagca agtgagtgca ccacttcata agtagcatca
    38521 gggatttgga gaaccttgac cgatactgga ttttccacac cagacaggtt gtcctgcatt
    38581 ccgtcaccga ccttactcaa gataggacct tgaacttcga caacttctag cttatctttc
    38641 aaatactggg taaaagtgtt tttgacaaag gaaatttctt cttgttgatg gataaaactt
    38701 ttcttcatag acaactcctc aaaaatttaa taaacgtatt atacacctat ttccaagaaa
    38761 agaaaagaga aaatttaaaa aaaatcagtg tcactcaaaa cactgatttc atagaccttt
    38821 tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa atcaagatag
    38881 atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga ttgttcatag
    38941 gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa aaccatggct
    39001 acgctaatca tataatcaaa gaagccacta gccaagaaaa tattgactac catagcaatc
    39061 agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc tttcttggta
    39121 aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa ggcagataaa
    39181 actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt taaaacggag
    39241 taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct actggcaacg
    39301 aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc ctgcatcaaa
    39361 aagtaaacca actgagactg aaaaaccgtc aacataaggc ctgataccaa agcagatagt
    39421 ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag acctgcacgg
    39481 tcatgtataa tagtgtgatt catccatttc tccttttctg tgaacatctt tccttgatta
    39541 taacaaaaaa agttaaaatt agcttaaata gaagattaaa ataccggctg caaccgcaac
    39601 attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg cactttcagc
    39661 cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat tttctataga
    39721 aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca ctgggatagc
    39781 taccttttta gtttcgtcaa gaagcgcttg actagtcatc cggtaaatgg gcagatggaa
    39841 atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg acttatctga
    39901 aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc ctacattacc
    39961 aggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag cttgtcctac
    40021 ttcttctttt tgaaccacgg caacaattcc ctgtggagtc tgagaatccg ccaaatctag
    40081 caaaatatcc tctgaaatcc agacagtttg cggaaaagca gctaactgat ttcgataatt
    40141 ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt caaacaagtg
    40201 ccagccttca atcaaatagg cagacttgcg gtattttttt tggtgtaatt tcttggcatt
    40261 ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat aacacaatca
    40321 aaggggtttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca gggagtcggc
    40381 tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg tcgagtatgg
    40441 aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc tatcatggca
    40501 aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag ctacttagat
    40561 gtcaaactaa gcaactttcc tccctactat gactttaaaa tcgcaaatta ggtctccaga
    40621 actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt aaagaaggaa
    40681 taaaaacagt gaaatctatt aaacgttttg cactctcggc tatgggagtg gctatgttgc
    40741 ttgtcttgac tggctgtgtc aatgtcgata aaaccacagg tcagccaaca ggatttattt
    40801 ggaatacgat cggagcgcct atggctgaag ctatcaagta cttcgctact gataaaggtc
    40861 taggctttgg tgtcgctatc atcatcgtaa ccattatcgt gcgcttgatt atcttgccac
    40921 ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac gctctcaagc
    40981 atgtccttga gccacaccaa acacgtctca aagaagcaac tactcaagaa gaaaaactcg
    41041 aagcccaaca agccctcttt gccgctcaaa aagagcacgg catcagcatg tttggcggtg
    41101 taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac tttgctgccc
    41161 aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt tctccaagta
    41221 tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt tcacttcacg
    41281 gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg agcccactca
    41341 tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg gttgtcggtg
    41401 gtttcatgat gattctccaa cagtttatcg tcaactatat cgttcgtcca aaacttcgca
    41461 aaaaagtccg tgaagaacta gccaagaacc caccaaaagc aagtgctttc tctaaaccaa
    41521 gtggacgaaa agacgttacc cctgaacaac caactgctat cacaagcaag aaaaaacaca
    41581 aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta gctagtttgc
    41641 taagtctttt ttgcaagt
//
LOCUS       DBEROT010000015        41568 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.15, whole genome shotgun sequence.
ACCESSION   DBEROT010000015 DBEROT010000000
VERSION     DBEROT010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 41568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41568
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.15"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            93..338
                     /locus_tag="ACL8CG_000931"
     CDS             93..338
                     /locus_tag="ACL8CG_000931"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1343548.1"
                     /translation="MYMNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVC
                     LGYKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            complement(449..652)
                     /locus_tag="ACL8CG_000932"
     CDS             complement(449..652)
                     /locus_tag="ACL8CG_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS1343549.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(683..1291)
                     /locus_tag="ACL8CG_000933"
     CDS             complement(683..1291)
                     /locus_tag="ACL8CG_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1343550.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(1330..1500)
                     /locus_tag="ACL8CG_000934"
     CDS             complement(1330..1500)
                     /locus_tag="ACL8CG_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGS1343551.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(1512..2078)
                     /gene="amaP"
                     /locus_tag="ACL8CG_000935"
     CDS             complement(1512..2078)
                     /gene="amaP"
                     /locus_tag="ACL8CG_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGS1343552.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(2162..2326)
                     /locus_tag="ACL8CG_000936"
     CDS             complement(2162..2326)
                     /locus_tag="ACL8CG_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS1343553.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            2729..4210
                     /gene="mgaSpn"
                     /locus_tag="ACL8CG_000937"
                     /gene_synonym="mgrA"
     CDS             2729..4210
                     /gene="mgaSpn"
                     /locus_tag="ACL8CG_000937"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGS1343554.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            4572..5573
                     /locus_tag="ACL8CG_000938"
     CDS             4572..5573
                     /locus_tag="ACL8CG_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1343555.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            5723..6640
                     /locus_tag="ACL8CG_000939"
     CDS             5723..6640
                     /locus_tag="ACL8CG_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1343556.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            6651..7541
                     /locus_tag="ACL8CG_000940"
     CDS             6651..7541
                     /locus_tag="ACL8CG_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1343557.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            7570..9186
                     /locus_tag="ACL8CG_000941"
     CDS             7570..9186
                     /locus_tag="ACL8CG_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1343558.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            9196..10515
                     /locus_tag="ACL8CG_000942"
     CDS             9196..10515
                     /locus_tag="ACL8CG_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS1343559.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDNQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(10724..10796)
                     /locus_tag="ACL8CG_000943"
     tRNA            complement(10724..10796)
                     /locus_tag="ACL8CG_000943"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10761..10763),aa:Lys,seq:ctt)
     gene            complement(11061..12332)
                     /locus_tag="ACL8CG_000944"
     CDS             complement(11061..12332)
                     /locus_tag="ACL8CG_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGS1343560.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            12602..12841
                     /locus_tag="ACL8CG_000945"
     CDS             12602..12841
                     /locus_tag="ACL8CG_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343561.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            13005..13184
                     /locus_tag="ACL8CG_000946"
     CDS             13005..13184
                     /locus_tag="ACL8CG_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343562.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            13321..13500
                     /locus_tag="ACL8CG_000947"
     CDS             13321..13500
                     /locus_tag="ACL8CG_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGS1343563.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            13537..13989
                     /locus_tag="ACL8CG_000948"
     CDS             13537..13989
                     /locus_tag="ACL8CG_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGS1343564.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            14280..14750
                     /locus_tag="ACL8CG_000949"
     CDS             14280..14750
                     /locus_tag="ACL8CG_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGS1343565.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            14769..15857
                     /locus_tag="ACL8CG_000950"
     CDS             14769..15857
                     /locus_tag="ACL8CG_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGS1343566.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLVPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            15838..16266
                     /locus_tag="ACL8CG_000951"
     CDS             15838..16266
                     /locus_tag="ACL8CG_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1343567.1"
                     /translation="MELEISDFLGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKIYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            16404..17354
                     /gene="prmA"
                     /locus_tag="ACL8CG_000952"
     CDS             16404..17354
                     /gene="prmA"
                     /locus_tag="ACL8CG_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGS1343568.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            17356..18099
                     /locus_tag="ACL8CG_000953"
     CDS             17356..18099
                     /locus_tag="ACL8CG_000953"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGS1343569.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            18110..19906
                     /gene="pepF"
                     /locus_tag="ACL8CG_000954"
     CDS             18110..19906
                     /gene="pepF"
                     /locus_tag="ACL8CG_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS1343570.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQINLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(19966..20643)
                     /locus_tag="ACL8CG_000955"
     CDS             complement(19966..20643)
                     /locus_tag="ACL8CG_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGS1343571.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            20890..21660
                     /locus_tag="ACL8CG_000956"
     CDS             20890..21660
                     /locus_tag="ACL8CG_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343572.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            21653..22417
                     /locus_tag="ACL8CG_000957"
     CDS             21653..22417
                     /locus_tag="ACL8CG_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1343573.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            22841..23632
                     /locus_tag="ACL8CG_000958"
                     /pseudo
     CDS             22841..23632
                     /locus_tag="ACL8CG_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
     gene            23743..24411
                     /locus_tag="ACL8CG_000959"
     CDS             23743..24411
                     /locus_tag="ACL8CG_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS1343574.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEK"
     gene            complement(24436..24705)
                     /locus_tag="ACL8CG_000960"
     CDS             complement(24436..24705)
                     /locus_tag="ACL8CG_000960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343575.1"
                     /translation="MLKAVFEVIDKTDEVSSKHCFEVADRTDEVSLKHCFEVVDRTDE
                     VSLKHCFEVADRTDVVSNHTYGKVKLTWFEEIFEEYHTKKPCSSR"
     gene            complement(24755..25288)
                     /gene="queF"
                     /locus_tag="ACL8CG_000961"
     CDS             complement(24755..25288)
                     /gene="queF"
                     /locus_tag="ACL8CG_000961"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGS1343576.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(25593..25907)
                     /gene="trxA"
                     /locus_tag="ACL8CG_000962"
     CDS             complement(25593..25907)
                     /gene="trxA"
                     /locus_tag="ACL8CG_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS1343577.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(25924..26145)
                     /locus_tag="ACL8CG_000963"
     CDS             complement(25924..26145)
                     /locus_tag="ACL8CG_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS1343578.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(26245..26625)
                     /locus_tag="ACL8CG_000964"
     CDS             complement(26245..26625)
                     /locus_tag="ACL8CG_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS1343579.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(26768..27721)
                     /locus_tag="ACL8CG_000965"
     CDS             complement(26768..27721)
                     /locus_tag="ACL8CG_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS1343580.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(27789..28996)
                     /gene="sstT"
                     /locus_tag="ACL8CG_000966"
                     /pseudo
     CDS             complement(27789..28996)
                     /gene="sstT"
                     /locus_tag="ACL8CG_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            29135..29695
                     /locus_tag="ACL8CG_000967"
     CDS             29135..29695
                     /locus_tag="ACL8CG_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGS1343581.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            29752..30660
                     /locus_tag="ACL8CG_000968"
     CDS             29752..30660
                     /locus_tag="ACL8CG_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS1343582.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            30675..31202
                     /locus_tag="ACL8CG_000969"
     CDS             30675..31202
                     /locus_tag="ACL8CG_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGS1343583.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            31205..32311
                     /gene="yqeH"
                     /locus_tag="ACL8CG_000970"
     CDS             31205..32311
                     /gene="yqeH"
                     /locus_tag="ACL8CG_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGS1343584.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSNALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVALTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            32525..32836
                     /gene="yhbY"
                     /locus_tag="ACL8CG_000971"
     CDS             32525..32836
                     /gene="yhbY"
                     /locus_tag="ACL8CG_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGS1343585.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            32888..33517
                     /locus_tag="ACL8CG_000972"
     CDS             32888..33517
                     /locus_tag="ACL8CG_000972"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGS1343586.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            33517..34110
                     /gene="yqeK"
                     /locus_tag="ACL8CG_000973"
     CDS             33517..34110
                     /gene="yqeK"
                     /locus_tag="ACL8CG_000973"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGS1343587.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRSFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            34111..34611
                     /locus_tag="ACL8CG_000974"
     CDS             34111..34611
                     /locus_tag="ACL8CG_000974"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS1343588.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            34624..34977
                     /gene="rsfS"
                     /locus_tag="ACL8CG_000975"
     CDS             34624..34977
                     /gene="rsfS"
                     /locus_tag="ACL8CG_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGS1343589.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            35297..36037
                     /locus_tag="ACL8CG_000976"
     CDS             35297..36037
                     /locus_tag="ACL8CG_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1343590.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDETPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            36078..37889
                     /locus_tag="ACL8CG_000977"
     CDS             36078..37889
                     /locus_tag="ACL8CG_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NACHT domain-containing NTPase"
                     /protein_id="HGS1343591.1"
                     /translation="MNIPIPFGDILEKEVITNIPKIYQKLKQIYNDLQFKTEEELGVV
                     YQEYLQFTYKKYSTVKTLLYKNEGKFLYDFYEHVYLDDNNSDLIETSNTELIFEKTSN
                     VILTGTGGIGKSMLVKHIFINQVQQATSIPIFIELKSLNESDFSENELVDFIYQEVQN
                     HHLNLEKKYFKATLEAGRYTIIFDGLDEVNPSKRSWLDKEIKEFVTLYNSNRYVLSSR
                     PSEEFIGWNQFAEYEIKKLNREQALSLIDKLNYDEKVKRRFYRELKDHLYDTHESFAS
                     IPLLLTIMLMTYEAGASIPNNLTDFYNQAFYTLYQRHDASKSGYKRELKAKLTPEEFR
                     NILAYIGLKTFFEGKVDFDRTTLDEIITKYCFKNNLELKTNDIVYDATHSACMMLQEG
                     VSLKFSHRSFQEYFAAVGVNQLDDKLQKQILIKWSEADRNNIVAHKTFMNALFKIQKE
                     RTYKNLCIPIIERMDEKYSRMGDITEKIVTCFNYFICRKDSRENKLELHFLLTKEVHF
                     YFSLQFLIFANLGIDILSISDYENIEKLESDIVSNWKINERKYYNMLNDDEKTLINKW
                     INGWYFSRHNYLKEWSIKFIEETTTQKRSLQNIIDSI"
     gene            37913..39010
                     /locus_tag="ACL8CG_000978"
     CDS             37913..39010
                     /locus_tag="ACL8CG_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS1343592.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDSLAFGTEEVLD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
     gene            39248..39502
                     /locus_tag="ACL8CG_000979"
     CDS             39248..39502
                     /locus_tag="ACL8CG_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGS1343593.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            39506..39760
                     /locus_tag="ACL8CG_000980"
     CDS             39506..39760
                     /locus_tag="ACL8CG_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGS1343594.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            39951..41564
                     /locus_tag="ACL8CG_000981"
     CDS             39951..41564
                     /locus_tag="ACL8CG_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGS1343595.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSHEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
BASE COUNT        12796 a         7415 c         8897 g        12460 t
ORIGIN      
        1 tatacattat gaaaaagggg agatagaaag caaacagcct tgaaatcaat gttgactgcg
       61 attatgaacc tgaatcagcc cctcaaaagg gactgtatat gaatgaacgt taccagtgtt
      121 taaaaactaa agaatatcag gcacttttat cttccaaggg tagacaaatt ttcgctaaac
      181 gtaagattga tatgaaatct gtctttgggc agataaaggt ttgtttgggt tataagagat
      241 gtcatctgag aggtaagcgt caagtgagaa ttgacatggg attcatactc atggccaaca
      301 acctgctgaa atataataag agaaagaggc aaaattaaaa agctagagtt ccgcaattgg
      361 gaatctctag ctttttgttt tctgagaatc atcttgactc agactctttt gactaatgtt
      421 accaaaaaag ataaagtaac ttttaacctt atttatcgtc gccactcaac atgtttttaa
      481 caccttctac agcaccttct acagcgtctt tagcgtcttc ggcaacttct tttactttag
      541 aaacaacttt ttcagctgct ccttcttttt ccattttttc atcaccgatg gctttcccaa
      601 caccttcttt aatagaacct ttagcttgat ttaatttttc ttctactgac atgataattt
      661 ctcctgttat atttatttta tcttagttta cacgagtgtt ttcgtgagat actacaccat
      721 ttgctgcacc tttaacagct tctacacctt cgctaacttt ttcttgaaca gttgagaaac
      781 cagatccaag accagattta gctttttcga attgttctga agtgaattct cctgttgatt
      841 cagcaacgtc agatacgcga tcttgaaggc ttactgagtc tgcttcatgc tgttctttag
      901 ttttgatgtc gacaacgttt acgttgattt caacaatttc caagtcagtc attttagcaa
      961 cttctgaaga tacgatttct ctgatttctg aatataaagc tggaacattt ttttggtact
     1021 caacaataac gtttaagtca actgcaactt gtgttttacc aacttctacg ttaacaccac
     1081 ttgttacgtc atcgctgtta acgatttttt ctttaagatt tgagaagaaa ccaccatcga
     1141 ttcccaaaag acctgaaacg ttttctagtg aaagaccaat gattttttgg ataactttat
     1201 cttcgtaagt aagttcccct ttgatttcgt gagctacaac agtagcatct ttcttttcta
     1261 cgttagtgtt tgtgtttttt tcgtttgaca tatgaaactc ctttaattaa attagtaatt
     1321 tttatttttt tatttatcta tatagttttt ttcgatatat aatccagctg caactcccag
     1381 tgctcctaaa atcaatacaa atattgtttt gaagaagcca aaggagacaa tcaaacaagc
     1441 cagaaatacg cctatgagac cagcgataat tggatatcga tattgtttaa gccattccat
     1501 tttttacttc cttacttcac acgactaaca gtctttttgt tttgaggttt tggttggtaa
     1561 ttttttactg caacttcaag ttttacttga cgctcaatac caaaaaactg cttcaatcca
     1621 ttagttattt cattttgaat tatttggcat ctgtcagcga tgttgtctga aggaagaatt
     1681 ttaccttcta catgaacgaa acatttattt tttcgtaaat ttacatgaac agttgggttc
     1741 ttgatcaatc tatgatcact caccaaactt ctaacaaaac cttcgattgc cgaattcttt
     1801 aattttaatg tatcgttttt agtttcaagt tggatttcca agtaacgttt aggataaaac
     1861 atcacaacta aaatggataa taaaactaaa gttgatagaa ccactgtccc ccaaaagaca
     1921 tatctagcaa gatagaattc aactacggag ttctgtctcc agctaagtag atgaatacct
     1981 agatcactaa cttgatgata atctatcaaa acaggaagga aaattgtcaa gattaaaata
     2041 cagaaaataa tgaaacatat tttctttgct tttgacatat acaatccttt cgatttaaca
     2101 tttaaactat ttttcccgtc attgatttaa aaatagtttg ctaactttac tggcgaaaag
     2161 tttactttct acctgtaaag aatgacacta cagtaatcac aatcgctgca cctacaatag
     2221 atgggagcaa agccattcca gcgattgatg gaccccaact acctaaaaga gattgtcctg
     2281 catatgcccc gactaaacca gcgaatacat ttgcgatgat tcccatagaa ctactttttt
     2341 agtgatttta cctgccaaga gaccaataag acctccagca ataattgatc acaacactgc
     2401 ctaccctcct tttttatttt aatatcaaaa aatcaatttc tttgattaat actattatat
     2461 aactttaata tagaaaagtc aattatttcg attgttatta ttatataatt tttaaaatta
     2521 aaaatataat ctttagactt gaatttgatt ctgtattcac gccctcaata gacggtaaaa
     2581 taagaaaatt gtttatatat tgtctccgta gtgttattat acgaaataaa agattttagg
     2641 aaaagtcgtt atatcatgct atacctattc tttgtggtat aattgcaaga ggtttaatcc
     2701 gataatttat aaagagagaa agatattcat gagagattta ttatctaaaa aaagtcatag
     2761 gcaattagaa ttattagaat tattatttga acataaacgt tggtttcatc gttctgaact
     2821 agcagagtta ttaaattgta cagaacgtgc agtcaaagat gatctatccc atgttaaatc
     2881 tgcttttcct gacttgattt ttcattcttc tactaatggt atacgcatta ttaataccga
     2941 tgatagtgat attgaaatgg tttaccatca tttctttaaa cattcaactc atttttcgat
     3001 tttagaattc atcttcttta atgaaggttg tcaagctgag agtatttgta aagaatttta
     3061 tatcagttca tcttcgctct atcgtattat tagccaaatc aataaagtga ttaaaaggca
     3121 atttcaattt gaagtcagtc tgacccctgt tcaaatcatt ggaaatgaga gagacattcg
     3181 ttactttttt gcacaatatt tttcagaaaa atattatttc ctagaatggc catttgaaaa
     3241 tttttcatca gagccactat ctcaattgtt agaattggtt tataaggaaa caagctttcc
     3301 aatgaatttg tcaacgcata gaatgctaaa gttgctccta gttacgaacc tatatagaat
     3361 aaagtttggt cattttatgg aagtagataa agattctttt aacgaccaaa gtttggattt
     3421 tttaatgcag gcagaaggaa tagaaggtgt tgctcagagt tttgaatcag aatacaatat
     3481 ctctttagat gaagaagttg tttgccaatt atttgtgtct tactttcaaa aaatgttttt
     3541 catagatgaa agtctcttta tgaaatgcgt aaaaaaggat agttatgttg aaaaatctta
     3601 ccatctattg agtgatttta ttgatcagat ttcagtcaag tatcagattg aaatggagaa
     3661 taaggataat ctgatttggc atctgcataa taccgcacat ctgtatcgtc aagagttgtt
     3721 tactgagttt attttatttg atcaaaaagg gaatacaatc aggaactttc aaaatatttt
     3781 tccaaaattt gtttcagata taaaaaaaga gctttctcac tatttagaga ctcttgaggt
     3841 ttgttctagt tcaatgatgg taaatcatct atcttatacc ttcatcactc ataccaaaca
     3901 tttggtgatt aatttgctac aaaatcagcc taaactaaag gttttagtta tgagtaattt
     3961 tgatcagtat catgcaaaat tcgttgcaga gacactttct tattactgta gcaataattt
     4021 tgaactggaa gtttggactg aattagaatt atcaaaggaa tctttagaag attcacctta
     4081 tgatatcatt atttctaatt ttattattcc tcctattgaa aataagagac tcatctattc
     4141 aaataatata aacacggtct cactcatata cttgttaaat gccatgatgt ttattcgatt
     4201 agatgagtaa gcaaaaataa caaaaaaacg ctatttcgcg tttgaactgt acctcaaaag
     4261 ttagacagaa aaaatctaat ttttggggtg tttttgttaa gaaaagacct tcaatcattt
     4321 aagcaaaatg tacatctaga tttatagccc tctaaaactc ttgctttttt tgtagaagat
     4381 acgaaaaaag ccataaaacc aaggcttttc ctgttttatg tagatgttta cacatgaaaa
     4441 ttgaagtatt ttcaaaagct aattggagtg attttattca tgatgggata aatgatctgg
     4501 ccaaaaatga ttgagaaata gttgcttaaa aagcatttgc atgatactat atattgaaag
     4561 gaggtgataa tatggtagaa caaagaaaat caattaccat gaaagatgtt gctttagaag
     4621 caggagttag tgttggaact gtttcacgtg taattaataa agaaaaaggc attaaagaag
     4681 taactttgaa aaaagtggaa caagcgatta aaactttgaa ttacattcca gattactacg
     4741 ctagaggaat gaaaaaaaat cgaacagaaa cgattgcaat cattgtacca agtatctggc
     4801 atcccttctt ttcagaattt gctatgcatg tggaaaatga agtctataag agaaataaca
     4861 aattactctt atgttctatc aatggtacaa atagagagca agactatctg gagatgttgc
     4921 gtcataataa agttgatgga gtggttgcca ttacctatag tccaattgaa cattacttga
     4981 cgtcaggaat tccctttgtt agtattgacc gcacatactc agatattgcc attccttgtg
     5041 tttcatcaga taatgatgca ggtggaagag aagcagctaa acaattaatt agtaaaggat
     5101 gtcagcattt agcctttgtg ggcggacata atacaaccat taatgaaacc aaacgtcgta
     5161 gaatttcatt tgaaaagtat gtccaagagc ataaaatacc tcttagtatt tttgatttgg
     5221 atgagacagt tactgactat tatggaaagc tagagagttt cttggaagaa aattcttcta
     5281 tagatggaat ttttacaatc aacgatttta cagctttgga tgtgattgaa atactaaaaa
     5341 aaaatggcaa acgtattcct catgatgtcc aaattattgg atacgatgga attaaaatgg
     5401 ctggagatag agattatcta ctttcaacta ttgaacaacc attggaagaa atggcaaaag
     5461 aagcggttcg tattttgttt gatataattg atggaaagac tgttaatttg cagacaatcc
     5521 taccagtaaa atttgttgaa ggaaaaacaa caaaaaatga aaataagtct tgacagaaag
     5581 cgctatcaat gatagaatga attcagataa aaagatttat ttttaaaaca aaaatgaaac
     5641 gtttcaaaaa agaaataaaa agacagcgcc aagcgctatc ttttctagaa aaaaatgaaa
     5701 cgtttcaaaa aaggaggttg ctatgaatag caaagcgaag caagtttctc tttgggaaag
     5761 aatcaagaaa caaaaactct tgttattgat gactgtcccc ggtttagttt taacctttat
     5821 ctttaaatac atccctatgt atggggtttt aatcgcattt aaagattaca atcctttaaa
     5881 aggaatttta gggagtgatt ggattggttt ttctgagttt acaaaattca tatcctctcc
     5941 caactttggt atcttgttag ccaacacatt aaaattaagt atctatggtt tattgcttgg
     6001 ctttttacca ccaatcattc ttgcgattat gctcaatcaa ctcttgagtg aaaaagtcaa
     6061 aaaacgaatt cagctcattt tatacgcacc aaactttatc tcagtcgttg ttattgtcgg
     6121 tatgattttc ctcttctttt cagtgggagg accaatcaac aattttcttt ctatgtttgg
     6181 aatgaaggct gacttcttga caaatccaga cttctttaga cccttataca tctttagtgg
     6241 tatctggcaa ggaatgggct gggcttcaac gctctacacg gcaacattgg taaatgtaga
     6301 tccagcctta gtagaagcag ctcgactgga tggagccaat atcttccaac gaatctggca
     6361 cattgatatt ccagctctta agcctattat ggttatccaa tttgttttag ctgcaggtgg
     6421 aattatgaat gtcggatatg aaaaagcatt cttgatgcag acatcgttaa atttgccaac
     6481 ttctgaaatt atctcgacat atgtctataa agttggtctt gtatcaggag actattctta
     6541 ctcaacagcg gttggtttgt ttaatgcagt gattaacgta gtattgcttg ttgcagttaa
     6601 ccaaatcgtt aaacgcatga ataatggtga aggaatttaa ggaggaaagt atgaaaaatt
     6661 cgattatgga tacaaaattt gatagacgta tcttactctt aaataaaatc attattgtct
     6721 ttatcgtttt gatgactttg cttcctttac tttatatcgt cgtagcatcc tttatggatc
     6781 ctaaggttct ggttagtaga gggattagct ttaatccagc cgattggact gtagaaggtt
     6841 accagcgtgt attcagtgac caatctattc taagaggttt tatcaattct ctactatact
     6901 cttttggatt tgcagcttta acagtcttgc tatctgtgtt tacagcttat cctctttcca
     6961 aaaaagattt ggtagggcgc cgttggatta actacttctt gattgtgact atgttctttg
     7021 gtggtggttt agtcccaact tacttgctcg taaaagaatt gggaatgctc aatactccat
     7081 gggctatcat tgttccaggt gctgtcaacg tttggaatat tattcttgct agggcctatt
     7141 tccaaggatt gcctgaagaa ttagttgaag ctgctgtcat tgatggtgca aatgatttac
     7201 agattttctt caaaatcatg cttcctcttg caaaaccaat tatgtttgtt ctcttccttt
     7261 atgcttttgt aggacagtgg aactcatact ttgatgcaat gatttatatc aaggatccaa
     7321 acttggaacc attgcaactt gtacttcgta aaattctcat tcagagccaa ccaggtcaag
     7381 acatgattgg agcacaagcg gctatgaatg aaatgaaacg tttagctgaa ttgattaaat
     7441 acgcaactat tgtcatttcc agcttgccat tgattgttat gtatccattc ttccaaaaat
     7501 actttgataa aggaattatg gctggttcac ttaaaggata aaaaaagaaa aaataaaagg
     7561 agttttctca tgaaattcaa aacattctca aaatcagcag ttttgttgac agctagttta
     7621 gcagtacttg cagcctgtgg ctcaaaaaat acagcttcaa gtccagatta taagttggaa
     7681 ggtgtaacat tcccgcttca agaaaagaaa acattgaagt ttatgacagc cagttcaccg
     7741 ttatctccta aagacccaaa tgaaaagtta attttgcaac gtttggagaa ggaaactggc
     7801 gttcatattg actggaccaa ctaccaatcc gactttgcag aaaaacgtaa cttggatatt
     7861 tctagtggtg atttaccaga tgctatccac aacgacggag cttcagatgt ggacttgatg
     7921 aactgggcta aaaaaggtgt tattattcca gttgaagatt tgattgataa atacatgcca
     7981 aatcttaaga aaattttgga tgagaaacca gagtacaagg ccttgatgac agcacctgat
     8041 gggcacattt actcattccc atggattgaa gagcttggag atggtaaaga gtctattcac
     8101 agcgtcaacg atatggcttg gattaacaaa gattggctta agaaacttgg tcttgaaatg
     8161 ccaaaaacta ctgatgattt gattaaagtc ctagaagctt tcaaaaacgg ggatccaaat
     8221 ggaaatggag aggctgatga aattccattt tcatttatta gtggtaacgg aaacgaagat
     8281 tttaaattcc tatttgctgc atttggtata ggggataacg atgatcattt agtagtagga
     8341 aatgatggca aagttgactt cacagcagat aacgataact ataaagaagg tgtcaaattt
     8401 atccgtcaat tgcaagaaaa aggcttgatt gataaagaag ctttcgaaca tgattggaat
     8461 agttacattg ctaaaggtca tgatcagaaa tttggtgttt actttacatg ggataagaat
     8521 aatgttactg gaagtaacga aagttatgat gttttaccag tacttgctgg accaagtggt
     8581 caaaaacacg tagctcgtac aaacggtatg ggatttgcac gtgacaagat ggttattacc
     8641 agtgtaaaca aaaacctaga attgacagct aaatggattg atgcacaata cgctccactc
     8701 caatctgtgc aaaataactg gggaacttac ggagatgaca aacaacaaaa catctttgaa
     8761 ttggatcaag cgtcaaatag tctaaaacac ttaccactaa acggaactgc accagcagaa
     8821 cttcgtcaaa agactgaagt aggaggacca ctagctatcc tagattcata ctatggtaaa
     8881 gtaacaacca tgcctgatga tgccaaatgg cgtttggatc ttatcaaaga atattatgtt
     8941 ccttacatga gcaatgacaa taactatcca agagtcttta tgacacagga agatttggac
     9001 aaaattgccc atatcgaagc agatatgaat gactatatct accgtaaacg tgctgaatgg
     9061 attgtaaatg gcaatattga tactgagtgg gatgattaca agaaagaact tgaaaaatac
     9121 ggactttctg attacctcgc tattaaacaa aaatactacg accaatacca agcaaacaaa
     9181 aactagaggt tgattatggg agataagaaa tacacagtag aaaaagccaa tcgttttata
     9241 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     9301 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     9361 tatcaattct atccatatga tagtgtttgg ggacctatgc actggggaca tgctaaaagt
     9421 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     9481 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     9541 actgggcata tcgaagaaaa aaccggtgtc cgccaagtgc aaaatatggc attttcagac
     9601 gacgggattc actttgaaaa gattgaacaa aatccagttg caactggagc agacttgcca
     9661 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     9721 tactccgtag tagctgccaa acacaagaat aatgtgggct gtatcgttct actagggtcc
     9781 gataacctag tagaatggca gttcgaatcc atctttttaa aaggggtaga acaccaaggc
     9841 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     9901 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     9961 acgggtaagg tagattgggg agaaaaatgt tttatcccag aatcagttca agaaattgat
    10021 catggccaag acttctatgc gcctcaaaca ttgttggaca atcaaaatcg tcgtatcctg
    10081 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
    10141 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
    10201 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
    10261 aatgatatag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
    10321 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
    10381 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
    10441 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
    10501 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
    10561 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
    10621 tggtgttgga ttatgattta aactagtttt ctaaagaatt tgaaaaaaat tttatttaag
    10681 caaaaaaaac cttggttcca agacttttcc tgttgtattt agatgccccc tacagggatc
    10741 gaacctgtga cccacggatt aagagtccgc tgctctgcca gctgagctaa ggaggcaaag
    10801 aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt gaacccgcgc aattaagcag
    10861 gtgggcaact cgctctaact gaagctgttt ccgtgtgaga cggcctacat gctgttagaa
    10921 gacttttgtt tccctaataa tacaaaaaat agtcggtcaa cacttaagtg tgaagtcgta
    10981 caccacagcg tttctatact tatatgatac cactttttca aaaaaaatca agaggaaagt
    11041 gcaatttttt gaaaaggatt tcagattttt cgcaaacgat cgatagcttc ctttctttga
    11101 gccaaagccc gttcatattt accagtatct tctgcttgga aatagtgatg attacgaatt
    11161 ttttctggca gatagtcttg cttgatccaa tttccaggat agttgtgtgg atagagatag
    11221 tcttgggcat tccccagttc cttgcttcca ctgtagtgcc catcacgcag gtgtcgcgga
    11281 ataggcaagt gccctgatgt tttgaggtca gcaagtgcct tatccatagc tacataggct
    11341 gagttggatt ttggagaaag ggccaaatca atcacgacat tggcaatgag aatgcgggct
    11401 tctgggaacc caatcttctg ggcagcatcc agagcagtca cggtatgaat ctgggcctca
    11461 ggattggcta agccgatatc ttcataggcg ataacagtca agcgacgagc gagactaggc
    11521 agatccccag cctcaatcaa gcgggcagta tagtggagac tggcatccac atctgagcca
    11581 cgaatagact tttgcagggc agatagaaca tcatagtgac cgtctccatc cttgtccata
    11641 gtgatgtagc ttctctgaag actattttcc atgatgtcta aggtgatgtg gcgaatgccc
    11701 tcgtcattct caggggtaga gagaacagcc aagtccagtg agttaaaggc agagcgaagg
    11761 tctccgtttg tagaggttgc gatgaaatcc agcgcatcct catctagttc tattggaaaa
    11821 tcaaaaccac gttcagggtt acttagagct atctgcaggg cctctttgac gtcttggtta
    11881 gacagaggtt ccaactcgaa aatttgaaca cggctacgaa tggcaggagt gacagagaag
    11941 aaaggatttt cagtcgttgc tccaatcatg atgaccagtc cactttccaa gagaggcaag
    12001 aggaagtctt gcttggtctt atctagtcga tgaatttcgt ctagcaatag gacgagacca
    12061 ccagaaaatt tagcttcttc cgagatttct tgcagtcgct ttttactatc aactgtcgca
    12121 ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg cagaggcaat actggttttg
    12181 ccgattcccg gagggccata tagaatcatg gaggacaggc ggttggcttc caccatgcgg
    12241 cggatgattt ttccaggtcc gaccagatgc tcctgaccga tgacctggtc gatggtttta
    12301 gggcgcatgc gaagcgcgag attgtctggc atagcagtcc tttctaacgt ggatttgagt
    12361 agaatgactc atctactata tcttactatg tccattctag cctattagtt gtgatatttc
    12421 aatggttttg taataatcag ggagtgagat agaatctttt ttactattta atttaatgag
    12481 gagaggtatc agcatgagag atttgatttt ccttaaagct caaaatagga tagttgagcc
    12541 taaagaagtg gaagtgctga cttgagaaat aatattgctg aatgtcattg tatgaactat
    12601 aatgaaaaga gaggtgataa gcaatggaaa tgatggacca agtcaggaaa ttttgatttt
    12661 tacaaaacaa attcgtcatt ggattcttag tgatcaagtt atttcaggga aaagaaaact
    12721 tttcttccgg gaagatactc caaaagagat tttagatttg tacgaaaaca ttaaatctaa
    12781 acttgatttt gcttaccaag aagttcattc taataatggg ttgaaaaaat atgaaaaata
    12841 gaataattga tgttttgaag tagtaaatcg cctccttgta ctaactgttg aaaatcctga
    12901 tttcgaagac ttgagagtta atcatactca atgaaaatca aagagcaaac taggaaacta
    12961 gccgcaggct gtacttgagt acggtaaggc gacgttgacg tggtttgaat ttgattttcg
    13021 aagagtatca gtttgtaaaa attggagata aaaaatatag agtacgcagt gttcctatga
    13081 ttcattcaac tccgcctcaa tctgtcttag atcgagatac ttttacaatt gactatacag
    13141 atgatgaatt gctcgataaa gaagcagttt ttactactca ttagaaaaat aggtctgaat
    13201 aaattggctt cccttagaac cacatctagg ggcttttatg tataatagaa taataagtat
    13261 cactccttta caatacgtgt aacacgtgtt ataatggtgt tgtcaggagg taaaagcgct
    13321 atgcctatga cacaaaaaga gatggttaaa ctccttacgg cccatggttg gataaagact
    13381 agaggcggta aaggctccca tattaaaatg gagaagcaag gggaaagact tatcacaatc
    13441 cctcatggtg agctgaataa gtacactgaa agagggataa gaaagcaagc tgggttgtaa
    13501 aattcagccc ctgttttttg atatggaggt agtgaaatgt tagttacgta tccagcttta
    13561 ttttattatg acgacacaga cggaacagaa gcgacttatt ttgtccattt cccagatttt
    13621 gaatactcag ctacacaagg agaggggatt tctgaggctt tggctatggg gtcggagtgg
    13681 ctagggataa ctgttgcaga tttgatagag agtgatggag agttacctca gccatcagat
    13741 atcaatagct tgtctttaat tgataatgat ccttttaaag atgatgaaga tttcgtgtca
    13801 acctatgacc ttgataaatc ttttatttct atggtatctg ttgatgtatc agaataccta
    13861 ggaagtcagg aacccattaa aaagactttg accataccaa aatgggcaga taagttggga
    13921 cgagaaatgg gacttaactt ttctcagact ttgacagacg ctattgcaga taagaaagtt
    13981 caagcctaag attaagcgtg gtatcgtggt aatagtcaat aaaaaagcac gtccacttgt
    14041 gctagttact cgcctattga ttttatagat ttattagccc tttcgagggc tttttatatt
    14101 gatttttatg agaaatgaag aaatcagact tttaagaaaa tcactgatac caagggttta
    14161 aatgaggtaa tatggtataa ttaggacata aaataatttt gtggtaagat ggtagtatct
    14221 attttagcat atttccgagc aatcggggcg attaaagagt cgcatagaaa gaggacaaaa
    14281 tggcaacata cggattttta gatattttag aggaagagtt ggacaagaac tttccctttg
    14341 actttgagat tagttgggac aaacgcaacc atgcggtaga agtgagtttt ctattggaag
    14401 cgcaaaatgc tgcaggtgtg gagatggtgg atgaagacgg agaggtttca tcagatgaca
    14461 ttctttttga ggaagcggtc cttttctaca atcctgccaa gtcaacagtc aatgaggaag
    14521 actatttgac tgttattcct tacctgccta aaaaaggatt ttcccgtgaa tttttagctt
    14581 attttgcgct tttccttaaa gatactgctg aggttgggct agatgtcctc atggactttt
    14641 tggaagaccc agaagcagag gaatttgtca tggaatggaa ccaagaagtc tttgaagaag
    14701 gaaaagttgg cttggaagag ggagaatttt acccttatcc aagatactag gagttggttg
    14761 gaggtgttat gaagaaaatt gggacttatt tggtttatgt gctagctgtt gtctttatta
    14821 tgctagcttt tgcttgtgga acaatcgcat ttgcagagtt ggggtattcc gcagttttag
    14881 cctttacttt tggttatgcc ttcgctcttc taagcatgta tttaatcttt attcttcatg
    14941 agctgggtca tgctttttgt ggctacttga caggctatcg gctggtggct tttggattag
    15001 gacattttat tttgaccaaa aagtcaggca ggtttcatct tagtagaaca gccattctga
    15061 aaaatgttgg tgctcaatac attggtttaa aagaggatga aagcgatcaa agaatcatcc
    15121 tgatgctttc aggaggcttg atggttcatc tcggcttgat attattggcg atagtgtttg
    15181 gatttttgac aagaagctgg tattttgcag ggacttggat ttttcttaat ttatctttct
    15241 tcctaaataa cattttgcca gtcgacatca ccgatggagc aaaaatttgg gaattactac
    15301 aacaccctga aaataccaaa tacgcctacc tggtattgag acattctgct caaactttgc
    15361 tggttcctca agaatatgat ttgaaagact ttgttcaagc agttcctgag gatgcacgag
    15421 ggagttttgc ggatggtgta ttaggtatgc aaggtgaagt ttccattttg gaagggaagg
    15481 aagaagtagc taaacagcag tttcaagcat tacttgagag gacaactact ccgatgatgc
    15541 agacagttgc ccaactatcc ctgcttcata tcgccttgtt ggaaggagat tttgagcaag
    15601 cggagcaata tgctagtatt cgacaggtca aatcgtttct gtctctcaaa ctgtccaatc
    15661 ttcaagtgat acaagcctgg tatcaattaa aggtgaagaa agatgtagat cgaactcgta
    15721 aggctctcaa gattgctaga cagaaaatgg atagtagtcg aatgttgagg gacgagaaac
    15781 gctattatga aaacttgtta gcagagctgg aaaaggaaat gttagaagga actgaagatg
    15841 gaactagaaa tttctgattt cctaggctgt aagattgctt tgttttgtgg ggataagctt
    15901 ttgactatct tacgcgatga taaggcaagc attccctggg ccaatatgtg ggaactgcca
    15961 ggtggtggac gtgaaggtga tgaaagtcct tttgagtgtg tagcgcgtga agtttatgaa
    16021 gaactgggca ttcatctgac tgaagattgt ctgctttgga gtaagattta cccaagtatg
    16081 ctttttgcag acaaacagtc cgtttttcta gttggtcagt tgacacagaa ccagtttgac
    16141 agtatcgtat ttggagatga aggacagggc tatcagctga tgaatgttga ggaatttctt
    16201 agttccagtc aagttgtgcc tcagttgcaa gagagattaa aagattattt aaaagtaagt
    16261 gattagaaag gatggttcgg ttaaatttct aaactgaacc cgccctaaac acggtgccaa
    16321 aaagataaac ttctcttaga cacaaacgtc ttcagagaat ttcctatttt ggttttgtgt
    16381 tttacgggct tggtatctta ataatggaaa catggcaaga gttaaaagtt acagtgaagc
    16441 gtgagggaga ggagttggtt tccaatctct tgattgagct aggagcgcaa ggagtcgcaa
    16501 tcgaagacag tatggactat atgggaaatg tggatcgttt tggcgagatt ttcccagagg
    16561 tggagcagca agaagaaatc gtagtgacag cctactaccc tgacacggtg gatgtgacag
    16621 tggttgaggc ggacttgcag gctcgcttag cagaattgac ggattttatg gatttgggtg
    16681 aagtcaagat ggggacgact gccttggctg aggaagactg ggcagacaac tggaagaaat
    16741 actatgagcc agctcgtatc actcatgatt tgaccatcgt tccctcttgg acagactatg
    16801 aggcgactgc gggagaaaaa attatcaagc tagatcctgg gatggctttt ggtactggga
    16861 cccatccaac taccaagatg agcctctttg ccttggaaca ggttcttcgt ggtggcgaga
    16921 cagtgctaga tgtggggact ggttcagggg ttctctccat tgctagctcg ctacttggtg
    16981 ccaaggaaat cttcgcctat gacctagatg atgtagcagt tcgtgttgct caggaaaata
    17041 ttgaacttaa ccctggaatg gaaaatatcc acgttgctgc tggagacttg cttaagggtg
    17101 ttgagattga ggcagatgtg attgtagcta atatcttggc ggatattctc attcatctga
    17161 cagacgatgc ctatcgtttg gtcaaggatg aaggctacct gatcatgagt ggcattatca
    17221 aggacaagtg ggacatggtg cgcgagtcgg ctgagtcagc tggatttttc cttgaaaccc
    17281 acatggttca aggggaatgg aatgcctgtg tctttaagaa aaccaaggat atttctggtg
    17341 tgattggagg ctagcatgca gcagtatttt gtaaaaggca gtgctatctc tcctgtcact
    17401 atcgaggaca aggaaaccag taagcatatg tttcaggtta tgcgcttgaa agaagaggat
    17461 gaggttacct tagtctttga tgatggcatc aagcgcttgg cgcgcgtgct ggatatggaa
    17521 aatcgtcagt ttgagttggt ccaagaatta aatgacaatg tggaactacc agttcaagtg
    17581 accatcgcat ctggatttcc caagggagac aagctggagt tcatcgctca aaaagtaacc
    17641 gaactgggtg ctagccaaat ctgggccttt cctgcagact ggtcagttgc caagtgggat
    17701 ggcaagaaat tgggtaaaaa agttgaaaaa ctagaaaaaa ttgcccttgg agcagccgag
    17761 caaagcaagc gtaatattgt accaagtatt aaacttttcg agaaaaaagc agattttcta
    17821 actcagctgg accagtttga ctctatcata gtagcctatg aagaatcagc taaagaagga
    17881 gaagccgctg cgcttctgca agcagtcact ggtcttgaaa caggagccaa actgctcttt
    17941 atctttggtc cagaaggcgg tctctcacct gcagaaatcg aaagttttga agctaaggga
    18001 gccgttttgg taggcctagg tcctcgtatt ttgcgagcag aaacagcacc gctttacgcc
    18061 ttatcagccc ttagtgtttt agtagaatta gagaaataag aggaagaaaa tggaacaaaa
    18121 acaccgttca gaatttccag agaaggaact ttgggattta acagctctat accaagaccg
    18181 tgaggatttc ttgcgtgcaa tcgagaaagc tcgcgaagac atcaaccagt ttagccgtga
    18241 ttacaagggc aatcttcaca cttttgagga tttcgagaag gcctttgcgg aattggaaca
    18301 gatctacatt cagatgagcc atattggcaa ctatgctttt atgcctcaga cgacggacta
    18361 tagcaatgac gaatttgcaa atattgctca agctgggatg gaatttgaaa cagatgccag
    18421 cgtagccttg accttctttg acgatgcctt ggtggtagca gacgaggaag tcttggaccg
    18481 tttgggtgaa ttgcctcact tgacggcagc tattcgtcag gccaaaatca aaaaagccca
    18541 ctatctaggg gctgatgtgg agaaggcctt gaccaatctc ggtgaagttt tctatagtcc
    18601 gcaggacatt tatactaaga tgcgagctgg ggattttgaa atggctgact ttgaagccca
    18661 tggcaagacc tataaaaaca gctttgtcac ctatgagaat ttctaccaaa atcacgagga
    18721 tgctgaggtt cgtgagaaat ccttccgttc cttctcagag ggacttcgta agcaccaaaa
    18781 tacggctgca gcagcctatc tggctcaggt caagtctgaa aaactcttgg ctgatatgaa
    18841 gggatacgac tctgtctttg attatcttct agctgaacaa gaagtggacc gtgtcatgtt
    18901 tgaccgccag attaacctca tcatgaagga ctttgcacca gtcgctcaga gatacctcaa
    18961 gcatgttgcc aaggtaaatg gtcttgaaaa gatgaccttt gcagactgga aattggactt
    19021 ggacagcgcc ctcaatcctg aagtgactat tgacgatgcc tatgatttgg tcatgaagtc
    19081 ggtagaacct ttggggcaag aatattgtca ggaagttgct cgttaccaag aagagcgctg
    19141 ggtggacttt gctgctaaca gtggcaagga ttccggtggt tatgcggcgg acccatatcg
    19201 cgtacaccct tatgtactca tgagctggac aggccgtttg agcgatgtct ataccttgat
    19261 tcatgaaatc gggcattctg gtcaattcat cttttcagac aatcaccaaa gctatttcaa
    19321 cgcccacatg tcgacctatt atgttgaagc accgtcgacc ttcaatgaat tgctactcag
    19381 tgattactta gagaaccagt ctaatgaccc acgtcaaaaa cgcttcgctc tggctcatcg
    19441 cttgacagac acctacttcc ataatttcat cacccacctc ttggaagccg ccttccagcg
    19501 taaggtgtat acattgattg aagaaggaga aaccttcgga gcaagcaaac tcaacagcat
    19561 tatgaaggaa gttttgacag atttttgggg cgatgccatt gaaatcgacg acgatgcagc
    19621 tttgacttgg atgcgccaag ctcactacta tatgggcttg tatagttaca cttactctgc
    19681 tggtcttgtc atctcgacag ctggttacct tcatcttaaa aactcagaaa ctggagctga
    19741 agactggctc aatctcctca aatcaggtgg tagcaagaca ccacttgagt cagccatgat
    19801 tatcggtgct gatatttcaa cagacaaacc actccgtgat accatccaat tcttgtctga
    19861 cacagttgac cagattatcg cctacagtgc tgagttgggg gagtaagggg atagagaggt
    19921 tgttatagaa tgggtatgga cagttatttg cttaaaagtc catgtttaaa tcccccattc
    19981 cttttcgagg aattctttgc ccttctctgt aatggtaagt gaacgtggcg tttgtgcagg
    20041 gatgaccaat tgtttttcac tgaaaaattc taaaagagca ttgccgagag ctccgccgac
    20101 atgattttta cgttcgctcc aatccaaaca tttagggcaa aatttccgtt ttttcttttt
    20161 caattcatcc gtatcaatgt gtaattttct ttggaaataa gacttcccag cttcagtgag
    20221 ttggaagtct ttttctgatt cgctgaggag attttcttgc aagagataat tggtaatgga
    20281 aatgccaagc tcaccagcaa tatggtcata gcaggtgcga gcgaccttta attccttttt
    20341 gtgaatgtgt tgtttataac ttttgacatc acgctgagga gagtagaagc tgagaaattc
    20401 cagcatttct gcaatggcag cactttttaa agaataataa tgaaaacgtc cataggtttg
    20461 tagagtggtt acctgcgctt cggtaagtaa tttgaggtga tagctgacag tatgttgctt
    20521 gattttggta aagctggcaa tttcgttaac cgtgtgagct tttccatcca ttagaatatc
    20581 taaaatgtgc atccgagaag ggtctgataa gagttttgtg atgatgaaaa tatctggttc
    20641 cataaaaatt ttctccaaat ttcatatatc gatgattttc tatcttttat tatactataa
    20701 ttaaagcaca agaaaaatag attttaaaaa tgttttacta gagaatattt taaattttat
    20761 tgtctgagtt taaatggagg taaaattaca aaagtaattg cagcagtatc cacagttgaa
    20821 ggacgttaat cttaagatta cattctcaac attttttcaa aagtgagatg aattaacaaa
    20881 gtatccaaca tgctctattt gtgggggaaa gaaagagtga agaagttaag tgttaaaaat
    20941 ctaaaaaagc aatatggttc ttatgaagct gtcaagggaa ttagctttga attgggagac
    21001 ggagagtgtt tgggtatctt gggaatcaac ggtgctggca aaacatccac tttaaagatg
    21061 atttactcac tgacctcaat ttcctcagga gagattgata tcttggggca aaatattgaa
    21121 accaatcgtc gtaagagtaa atcttgtctg ggtattgtag ggcaggagga tatgctggac
    21181 atgaccttga atgtttatga taatcttttt gctcacggtc tatgttatgg tatctcatct
    21241 gtcgaactta ggaagagaat cgattctctc ttggattttg ttcaactgag caaacatgcg
    21301 caaaagatgg tgaatcagct gtcgggtggg atgcgacgac gtcttgtctt ggcaagagct
    21361 ctcatcaatc ggcctgatat tatcatttta gatgaaccga cagttggttt agacattcaa
    21421 tcccgcaata ttatttggga taaacttttg gaattgaagg aattaggtgt ttctatcatt
    21481 attacttccc actatatgaa tgagattgaa tatttgacag atagggtgct gatgctccac
    21541 caagggacta tcaaagaaga aggaactgta gaagacttgc tcatcaagta tgatgctgac
    21601 aaccttgaga cgcttttttg ggggttgact gggacagaga aggaggactt gcatgtttaa
    21661 gttatcattt cactccatcg gacacgttgt ggtacgcaac tacatgagtt ttagaaattt
    21721 atttaaaatt tcaattgtcc ccaaccttat cgaccccctc ttttatcttt tagcaatggg
    21781 atttggagtt ggtgcttatt tgacgcatgt taacggtatg ctctaccgtg attttgtcat
    21841 tacaggttta attgctgcga ctgccatgtc tgcggccacc gcagaaacaa cggtcaatgc
    21901 ctttatccag tataagattg aaaagactta tgatgctatg ttgatgacgc caatcaatac
    21961 gaatgatatt gtggtaggtc aggctatctg ggcaggtatt cgtgcagtga ttttcggtgg
    22021 gattttttgg ctgatttcca tgcttatcac agcgcatttt catgtcttga tgttattgat
    22081 tcctctgatt ttatttatag tgggttattt gtttggtgtt ttgggactaa tctttaccta
    22141 cttggcgccg tctagggaat ttctgaatta ctacaatgtt ttggtaatcc gtcctcttta
    22201 tatgttttca gataccttct ttcccattac ttccttgccc ccaatacttg gtgatttgac
    22261 ttggttttct cccttgtatc acgctacccg catgattcgt attatatggg gaggtgaggt
    22321 gacaggtttg tatcttcatc ttatctggtt gatagccttg gcgctcttga taacggtgct
    22381 tcctatgtat atgttacatc gtagatatta tagatagtct aattatttgt gatgttgtag
    22441 tcatattcta atttatacta aacgttattc gaatttggac aggtatggga actgtgccta
    22501 tcaatattgt aatttatgga agttgaaata gtacggttca gtttttaaat attgttagaa
    22561 attgttttaa attccctaat caatttgtat agtttttatt tcactttatt ataactagtt
    22621 tttcgcaatt tttgagacag gaatgtgatt tttgtgataa ggttctatca ttacaagttt
    22681 atttgttgta atatggaata aatcatttat atatcttttc agaaatatgc tgtttctctg
    22741 aatataaatg tctttttctt tttaacttaa ttttacaaat tggtaaggtc atttaagact
    22801 gcctttttga acagttgcta gaaatgtaga ggtattgacc atgtatcaag atttactaag
    22861 aaaaatagca gaagaaaaac caaattataa ccaggaggaa atccagtggt tgcttgatca
    22921 tttgggagat ccttctccag aaattcgtga tgaccttgtt tttacaagct ttgctagagg
    22981 gattcaggaa gagctattta cacaggaaca atttcatttc attgctgaag gggtttcatc
    23041 tgatggaggg ttagataaag agattgataa gataggcctg ccaacacttg aacgttcttt
    23101 tagggcgctt atttatgcaa ctctcttgtc tgacgatgcc aaccagcaat cggtttttta
    23161 tcaggaatta aatgcaggat ttcgtaatga cctttcaaat caaggcttgc actatctttc
    23221 aaaagaaaag gatacaacag gtttctcaag tcagtatggt tgggttcacg cttttgcaca
    23281 tggagccgat ttactgacag aggtggtttg tcatccagac tttcctaaaa acagagttca
    23341 tgaagtattt gatatacttg gccaactatt taaaaggatg tcgattcgct ttacagatga
    23401 tgaggattgg cgtttagcaa gagtgatcta tgaacctatt ttataaggga agttggagca
    23461 agaacaagta gcttcttgga taaaaactgt tgattttccg atagaagaaa gggaggattt
    23521 ttacaaattt tccaacttta gatcctgtct ggtggaagtc tatgtccaac ttgaccagag
    23581 aaatagttta caagatgagt tgaaagaagc tatccagtct tttcaatact agagattagc
    23641 taatagttct atgattttca aaaaatttcc aatcaatttt cttgaaaccc tttcctactt
    23701 ttgatagact agtatctagt ttttgaaaaa aggagaaaga aaatgaaaaa atttgttgct
    23761 gagttaatcg gtacgttcat gcttgtgttc gttgggacag gagctgttgt ttttggaaat
    23821 ggtcttgatg gccttggtca ccttggaatc gcctttgcct ttggtttggc aatcgtggtg
    23881 gcagcctact caatcggaac tgtttcaggt gctcacttga acccggctgt ttcgattgct
    23941 atgtttgtaa acaaacgttt gtcatcttca gaacttgtaa actacatcct tggtcaggtt
    24001 gttggagctt tcatcgcttc tggcgcagtc ttcttcctct tggctaattc aggtatgtca
    24061 actgctagtc ttggtgaaaa tgccttggca aacggtgtca ctgtctttgg tggtttcttg
    24121 tttgaagtca ttgcaacttt cttgtttgtc ttagttatta tgactgtgac ttcagaaagt
    24181 aagggcaatg gcgcgattgc tggtttggta atcggtttgt cattgatggc gatgattctt
    24241 gtcggattga agattactgg actttcagta aacccagctc gtagcttggc accagctgtc
    24301 ttggtaggcg gcgcagccct tcaacaagtt tggattttca tccttgcacc aatcgctggt
    24361 ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa cagaaaaata attgaaactc
    24421 aaaaagcctt gctcctcatc ttgaggaaca gggctttttc gtatgatact cttcgaaaat
    24481 ctcttcaaac cacgtcagct ttaccttgcc gtaggtatgg ttactgacta cgtcagttct
    24541 atctgcaacc tcaaaacagt gttttaagct gacttcgtca gttctatcta caacctcaaa
    24601 acagtgtttt aagctgactt cgtcagttct atctgcaacc tcaaaacagt gttttgagct
    24661 gacttcgtca gtcttatcta taacctcaaa cactgctttg agcaacctgc ggctaacttc
    24721 ctagtttgct ctttgatttt cattgagtat gactttagcg gttgtcaatt ttctctggat
    24781 aaaggtcgtg ttggaagagg cgttgttctg ccaagtcctc atacttagtt ccttgcttac
    24841 cgtagttgta gtaggggtcg attgaaatgc caccgcgcgg agtgaatttt ccccagactt
    24901 ctaaatagcg agggtctagc aagttgacca agtctttccc gatggtgttg atacagtttt
    24961 cgtggaaatc tccgtgattt cggtagctaa atagatatag tttgagggat tttgactcga
    25021 cacagagctt gtcaggaatg taggaaatat gaatcgtcgc aaagtctggc tgagcagtga
    25081 tttgtcccag cagagacata tcgaggatat ggtgacgaat gccctgttcc ttagcgattt
    25141 ctctagcaat ttgaatttcg aggtgatgac gttggccgta ggcaaaggtg acagcttcga
    25201 ctgtttcata gtgttgcata acccagaaaa ggcaggttgt tgaatcttga ccaccactaa
    25261 agacgaccaa ggctgattga cgtttcatag tactccttcc aaaatgggaa atgttcagag
    25321 catgcaaaaa gctcctatta gggagctaaa aaataccaaa tcgagttttt ttagcgatgg
    25381 catatcccaa acatcgtaat attctactta tatagtaaaa tgaaataaga acaggacaaa
    25441 tcgatcagga cagttaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    25501 agtttcaatc tactatagtc tagcatattt tttgaaaaat ggcaaagggc aagaaaaaag
    25561 agaccaaaga aagtacttgg tctctcgttt gattagctca attcagcaat gatggccttg
    25621 atttgttctg ctgtgtgaac acctgcaact tgtttgacaa cttggccgtc ttttttgaag
    25681 agaagagttg gaatagacat gattccaaaa gcacgagctg tgtttggatt ttcatcaacg
    25741 tccattttaa cgattttcaa gacatcttct gaaagttctt cagacaattt gtccaagatt
    25801 ggaccttgca tacgacatgg accacaccaa gttgcccaga agtctactaa gaccaaacca
    25861 tcttttgttt cttgttcgaa tgttgcatct gtaattgctt ttgccattgt atttctcctt
    25921 tttttagtta tattggctta aatcttgttt catgagatag aagaagatat ctccataagt
    25981 cccatggtag tccaaattat gacccttgta agttaatttt tggacagggt agtagtctgc
    26041 gacgccgata aggcaagctt gttgcgaacg ttcaaagtct tcataagact cgaaagtcac
    26101 agttctttcg ttcttgctgg catctatata ggtaatttca atcatattta aaactccttt
    26161 gtttaatgct aactttattt tactccttat aaaagagaat gtcaagaaaa atgattgcgc
    26221 acgcaacttt ttttaaaaat catcttaaat caagaaatcc aaacctgctt ccaagctttc
    26281 ttcgacagtc ttttgtagcg aggccagtgt cttttgccca tcatttgtca ggcagataaa
    26341 actagagcgt ctatcttgat ggcaacacat gcgactgagt agaccgcaat ttttagcttc
    26401 caagcgagcc accatcctag aaactgcgct cgggctcaga tgaagtttat ctggcaggtc
    26461 aatctggcgt agagattttt cttcagccaa gtccagatag tagagcaggt agaactcttt
    26521 caaggtcaga ctttgctcgc tctgttgggc aatggtctct tccaagagac tttcaatttc
    26581 tttctgacgc cgattgaagt caaaccattt ttccaaatag gtcatagtgt ctcctttctt
    26641 tttagagtca taaatagaag aaagtccatt aacgggcagt ctctgcgtca caagatgatt
    26701 gcgcatgcaa taattatact acttttcaag aatgctggca agctctgttt tttagtggtt
    26761 ttatttttta ctgtctatat ttttggtaaa aatcaacttt tacttggatg aaggttttgg
    26821 cttcacgtag gagttgaaga agggtggcgc gggtttcaaa ttcttctctt gtcttgggca
    26881 gactgcggtt ccggaagact tccagataac gttcaatttc atctagcaaa tcagaagcag
    26941 gattggtctg gctcagttga cctgcaattt ttgaaaagag ttgcgctaag atcaggcttt
    27001 cactggcggc aaggtgacaa gtgttaatct gttgggccat gtttctcagg atacgacttt
    27061 gtcgttgtct catctcaaag tagtggatat ggtagtcggt ctggtgaaag aggtggtcag
    27121 agtgatccaa atagaccagt ctgagggctt ctttcaaaag cgtgtctaat tctgctacca
    27181 gctgtgctcg gttgcgtccg tctcctctgg ataaatagta tttgaagcgc tggaggatat
    27241 cttttaactt ttcttccacc agcgtgtggt agtgctggat ttcctcttct cgtgaaggca
    27301 tatagagatt aacaagcaag gcaaatcctg taccaatagc aaagagaagg aattcattga
    27361 ctagaaggtc tggagaggtt gactcttgaa ccaagagatg gctaaccaaa acagtgcttg
    27421 gtgtgatgcc aatttcccag cccatcttgt aggctaaagg aacgtagaag gccagataga
    27481 ggccgagact ccagatatga aatccgctca agtgaaaagc tagaacaccg atagccagag
    27541 ctagaagcat agaaaaaaga cgattgcgag ccagttttaa agtacttcta cgcgtatcag
    27601 ataggctcaa gagagcgata attccagccg aaactgctga tgaaagattg agaaaataag
    27661 caagcaggca ggcaagacag gtagctaaga tgagcttggt cgtacgttgg ctaatagaca
    27721 taagaatttc ctaataagtt agaataaaag cgtaaaagac aagacatgag caggcttgcc
    27781 ttgatgagtt attttttacg ggttgctgcg tattcggcaa cggcggtaaa gaggacatct
    27841 gtagaagagt taagggctgt ttcacatgag tcttggatga caccaatcac aaaaccaacc
    27901 ccaacaactt gtatggcaat atcgttagaa ataccgaaaa ggctacaagc aactgggata
    27961 agaaggaggg aacctccggc aatacctgaa gcaccacagg ctgagatagc tgctaccaca
    28021 ctgaggacaa aggctgtggc aaagtcaaca ggaattccaa gagtgttaac tgcagcaagg
    28081 gtcaaaacgt taatggtaat cgctactcca gccatattga tagtagaacc gagtgggata
    28141 gaaacagaat aggtatctgg gttgagtcca aggtcatggc agagtttcat gttgacagga
    28201 atgttagccg cagaactacg agtgaaaaag gctgtcacac cgctgacacg gaggcagttc
    28261 caaactagag ggtaaggatt gcgtctcata aagaagaagg caatcaaagg gtgaccacaa
    28321 gggcaacaaa aagcatagtc gttactaata gaaccaataa aataccgtag ttggtaaggc
    28381 ttccgactcc cttgtcagaa atggttttaa aaacaagacc aaggcttcca aatggagcca
    28441 gattgatgat ccattcgaca attttagaag tcacgtcagc gatagttttt agcaattctt
    28501 tactattttt actggcttct ctcatagcga ttccaaaaat gactgcccaa gataagattc
    28561 taatatagtt agcagtaaac agggcgttga ctgggctgtc aaccagtttg agcaagaggt
    28621 tgctgagaac ctgcccaacc ccatctggtg gtgcaatttc agtattggca ctatttaggg
    28681 taatttcaat agggacgatg aaacttgcta gtacagctac aagagcagcg gcgaaagtcc
    28741 ctatcatagg atatacaaga aaacaacagt tttcatattg ctatcttgtc ccttttgatg
    28801 ttggaaaggg cattggcaac gagggcaaag actaggatag gagcaacagc ttttagacct
    28861 ccaacgaata aatccccgag tagcccaatc cctgagagat taggaagggt cagtcctagg
    28921 attccccaca aagcatacca atcaagatac gcttgacaag gcttgcctta ttccaagcat
    28981 gaatgattct tttcataata atctcctttt tgtgtagtga ttatgattat agtataaatg
    29041 atagacaaaa tcaagaattt tctgtctatt ttttgaatat ttatggagaa tgagactgat
    29101 gaaaatatgg tataatgaaa taaaggagtt ttatatgcaa aaatttattc aggcttatat
    29161 tgaaaagcta gatgtgacaa ccattatcga gaatattcta accaaggtca tttctctttt
    29221 actgcttttg attgtatttt atattgctaa aaaaatgctt cataccatgg tgcagagaat
    29281 tgtcaaacct tctctaaaaa tgtctcgtca tgatgtcgga cgccaaaaaa ccatctcacg
    29341 tttactagaa aatgtgttta attatacgct atatttcttt ttactctact gcattttgtc
    29401 gattttaggt ttgccagttt ctagtttgct ggctggagct ggtattgctg gggtagcgat
    29461 tggtatggga gcccaaggct ttctgtctga tgtcatcaat ggctttttca tcctctttga
    29521 acgtcaactg gatgtgggag atgaggtcgt tctgacaaat ggaccgatta ctgtatcggg
    29581 taaggttgtc agtgtgggaa ttcgtacgac acagcttcgt agcgaggagc aagcccttca
    29641 ctttgtccct aaccgaaata tcacagttgt tagcaatttc tcacgcacag actagacctg
    29701 ttattttaag taatttgtgg tacaatagag ggagtttaat aaggagaaaa gatggtttta
    29761 gaaaagcagt tgggcaatgg ttgtacctgg atagacctag acctaggaaa gttgaataaa
    29821 ctagaagacc tttctgaaat ttacggtttg gacaaggaaa ccattgaata cgcactggat
    29881 agaaacgagc gcgcccacat ggactaccac cgtgaaagtg ggacggttac ctttatctat
    29941 aatgtcctag acgtaaaaaa ggacaaggcc tactatgaga cttttcccat gacctttatt
    30001 gtcgagcatc gtcgcctgat taccattagt aataccaaga acgcctatgt cattgaacag
    30061 atgactcgtt atctggagag ccatgacacg ctttcgattt ataagtttct ctttgccagt
    30121 ctggaaatca tcagcaatgc ctactatcct gtcattgagc agatggacaa gagtagggat
    30181 gaggtcaatg acctcttgcg ccagcgaact accaagaaaa acctctttgc cctgtctgat
    30241 ttggagactg gtatggttta tctaacggca gctgccaaac aaaatcggat tttgttagag
    30301 catattcaag gtcatgcctt gtatcgtagt tttgatgaga ttgagagaga acagtttgat
    30361 gatgccatga ttgaggctca tcagctggta tccatgacag acctaatctc tcagatttta
    30421 cagcagcttt cagcctctta caacaatatt ctaaacaata atctgaatga caatttgaca
    30481 accttgacta tcatttcagt cttgctagct gttttggcag tcgtgacagg ctttttcgga
    30541 atgaatgttc ccttgccttt aacagatgag ccccatgctt ggctctatat cagtttggct
    30601 agtgcaggtt tgtggattgt tttatccttg ttactaagga aaattgcgaa aaaaagttaa
    30661 gaaaaggagc cagaatggcg attgaaaatt atataccaga ttttgctgtg gaagcagtct
    30721 atgatctgac agtcccaagc ctgcaggcgc agggaatcaa ggctgttttg gtcgatttgg
    30781 ataataccct cattgcttgg aacaaccctg atggaacgcc agagatgaag caatggctac
    30841 atgaccttcg ggacgcgggt attggcatta tcgtagtgtc aaataacacc aaaaaacgcg
    30901 ttcaacgagc agttgagaaa tttgggattg attacgttta ctgggccttg aagcccttca
    30961 catttggtat tgaccgtgct atgaaggaat tccactatga caaaaaggaa gtggtcatgg
    31021 ttggtgacca gctcatgaca gatatacgag cagcccaccg tgcagggatt cggtcaattt
    31081 tagtcaaacc cttggtccaa catgactcaa tcaaaacgca gattaaccga actcgtgagc
    31141 gtcgtgttat gagaaaaatc actgaaaagt acggaccgat tacatataaa aaaggaattt
    31201 aactatggaa gaaattctct gtattggttg tggagcaacc attcagacga cagataaagc
    31261 tggtcttggt tttacccccc agtcggcact tgaaaaaggt ttggagactg gcgaagtcta
    31321 ttgccaacgc tgtttccgtc tccgccacta caatgaaatc acagatgtcc agttgacgaa
    31381 cgatgatttc ctcaagctct tgcacgaggt gggagacagt aatgccttag tggtcaatgt
    31441 cattgatatc tttgatttta atggatctgt catcccaggt ttaccacgtt tcgtctcggg
    31501 caatgatgtc ctcttggtag gaaataaaaa agatatcctt cctaagtcag ttaagtctgg
    31561 taagattagc cagtggctca tgaaacgtgc ccatgaagaa ggtcttcgtc cagtcgatgt
    31621 ggccctaact tcagcacaaa ataaacatgc cattaaggaa gtcattgaca agattgaaca
    31681 ctaccgtaag ggccgcgatg tctatgtggt cggtgtgacc aacgttggaa aatcaactct
    31741 aatcaatgct attatccaag aaatcacggg tgatcagaat gtcatcacta cttcacgctt
    31801 cccagggaca accttggaca aaatagagat tccgcttgac gacggatctt atatttacga
    31861 tacgccggga attatccacc gccaccagat ggctcactac ttgacggcca aaaacctcaa
    31921 gtatgtcagt cctaaaaagg aaatcaagcc taagacctat cagcttaatc ctgagcaaac
    31981 cctattttta ggtggtttgg gacgctttga ctttatagca ggagaaaagc aaggatttac
    32041 tgctttcttt gataatgaac tcaaactcca tcgtagcaag cttgaaggag ctagtgcttt
    32101 ctacgataag cacctgggaa ctcttctgac accaccaaat agcaaggaaa aagaagattt
    32161 cccaaggcta gtccagcatg tctttaccat taaagataag acagacctag tcatctcagg
    32221 cctaggctgg attcgtgtaa caggcatagc aaaagtcgcc gtctgggcac cagaaggcgt
    32281 cgccgtcgtc acacgaaaag caattattta aaacaaaatc gctgagcgaa caaagtgagc
    32341 tcatatagcg atagttattg ccgtggtgtg attgccaatc tgtagattgg caaggggcac
    32401 aattgagacc aaggctcaat tgtgaggtca ggaaatccat ttttcaaaga tgaaatcttt
    32461 ggaaaattag ttccgaccgt ccctcaccac ctaaaataac tatccaaaaa caaggaagaa
    32521 aattatgtca ttaacatcaa aacaacgtgc cttcctcaac agccaggcac acaccctcaa
    32581 acctatcatc caaatcggga aaaatggact caacgaccaa atcaaaacca gcgtccgtca
    32641 agctcttgat gcgcgtgaat taatcaaggt tactctctta caaaacacag atgaaaacat
    32701 ccacgaagta gctgaaattt tggaagaaga aatcggtgtg gatacagtcc aaaaaatagg
    32761 acgcatcttg attttgttta aacaatctag caagaaagaa aatcgcaaga tttctaagaa
    32821 agtcaaagaa atctaagacc gaaactccaa ataactgttt ttatagagaa ataaagggga
    32881 ctagcctatg acaatcgaac tattgactcc ctttaccaag gtagagttgg agccagaaat
    32941 caaggagaaa aaacgcaaac aagttgggat tttagggggg aattttaacc ctgttcacaa
    33001 tgcccatctc attgttgcgg atcaagtacg gcaacagttg ggactggatc aagttcttct
    33061 catgcctgaa taccaacctc ctcacgttga taaaaaggaa accatccctg aacaccatcg
    33121 tctcaagatg cttgagttgg caattgaggg gattgacggc ctagtcattg aaaccattga
    33181 gttggagcgc aagggtattt cctacaccta cgacaccatg aaaatcttga cagagcaaca
    33241 tccagatacg gattattact ttatcatcgg tgccgacatg gttgactatc tgcctaagtg
    33301 gtaccgaatt gatgaactgg ttgacatggt tcagtttgtg ggggttcagc gtccacgcta
    33361 caaggcagga acttcctatc cagttatctg ggtggacgta ccgctcatgg atatctcgtc
    33421 cagcatggtg cgggacttca ttgcccaagg tcggaaaccc aactttctcc tacctcagcc
    33481 agtgctagac tacatcgaga aggaggggct ctactgatgt cctatcaaga ctatatcaac
    33541 tgctcccgtg aggccttgtt ggaaaaaatg gcagagcttc tacctgagaa acgtctaacc
    33601 cattgtctag gtgtggagcg tgccgctatg gagttagctc agcgctttgg tgtagatgtt
    33661 gagaaagcaa gtctagcagg tcttcttcat gactatgcta aaaagttgtc aaatcaggaa
    33721 tttctagcct tgattgaccg ttaccagcta gaccctgacc tcaaaaactg gggcaataat
    33781 gtctggcatg gtatggtcgg aatttacaaa attcaggaag atttggattt gcatgattct
    33841 gaaattctgc gagccattga aattcataca gtcggagctg gtcaaatgac agacctagat
    33901 aaggtcatct acgtcgcaga ctatatcgag cacaatcgat cctttcctgg agtagatgtg
    33961 gcgcgtgaga ttgcaagtct atcgctcaat aaggcggtgg cctacgaaac agctcgtacc
    34021 gtggagtatc tagctcatca gggattcccc atctatcccc aaacccttga aacctataac
    34081 gcctttgtgc actatttgaa agaggactaa atgaagacgg cttttataat cattgatgtt
    34141 cagaatgttt tagtagaaac tgggttccag acaaaaagtc tattggaaaa aatttcttat
    34201 ttacaaaacc aggctagaag caagaatatt gaaattatct atgttcaaca tattgagaac
    34261 tctgaagctc aaacatcaga agattggcag ttatctgcgc ttttaaatcg aaaacctgct
    34321 gaaaaggtct ttcagaagaa gtataacagt attttcaaag aaactggctt aaaagaatac
    34381 ttggataaac aggggattga aaaattagtt ttatgtggta tgcagacaga atattgtgtg
    34441 gatacctctg tcaaggttgc ctttgaatat ggctatcagc ttattgttcc agaaggtgct
    34501 gtcacaacct ttgatgggga tgacattcca gcagaaacga ttaatgaatt ttatgaggac
    34561 atttgggagg agcgctttgc agatgtccta gattacaaac atattttcta aaaagaggat
    34621 taaatgaacg aaaaagaatt actagaacta gtcgtgaaag cggctgatga gaaacgtgcg
    34681 gaggatatcc ttgcacttga tgtacaagat ttgactagtg tgacggacta ctttgtcatc
    34741 actagctcaa tgaatagccg tcagttggac gctatcgcag ctaatatccg tgaaaaagta
    34801 gctcaagcgg gctttaaagg tagccatgtc gaaggcgatg cagctggagg ctgggtctta
    34861 ctggacctcg gtgctgttgt cgtgcatatc ttttcagagg aaatgcgtgc ccattataat
    34921 ctagagaagc tatggcatga ggcgaattca gtagatattt cagaagctct tgcttagaag
    34981 atgaactcag ttgtagtcaa ctgggtttct ttgcttattt tagaaaaatt gatagaaagg
    35041 taaagggcct cgtgtttgtt tcatttcgaa actgaacacg agctaaaagc tgagataaaa
    35101 agtaactttc tttgtatctg acgataggga agaaagtttc ctatgtactc tttgctttta
    35161 aggctctttg tatcttagaa aggatttgaa cccgtcctgt aattatcgga aaatagatag
    35221 ccttccttgg agctcggctc catcgtaagg ctcctaattt tctatcgaat tacgggcgga
    35281 cttggtatca tgttttatgg cgacttatga aacctttgcg gctgtctatg atgcggtcat
    35341 ggacgatagt ttatacgaca aatggacgaa tttttctctg cgtcatttgc ctaagaccaa
    35401 ggagagaaag aaactcttgg aactggcttg tgggacagga attcaatcag tgcgcttctc
    35461 tcaggctggt tttgatgtga ctggacttga cttgagtgcg gatatgttga agattgcgga
    35521 gaagagagca acttcagcca agcaaaagat tgcttttata gaaggtaata tgctgaattt
    35581 gtccaaggca gggaaatacg attttgtcac gtgttattcg gactctatct gctatatgca
    35641 ggatgaggtg gaagtagggg acgtctttaa ggacgtgtac aatgcgctga atgaagaggg
    35701 agttttcatc tttgacgtgc actcgaccta ccagacagat gaagtattcc ctggctattc
    35761 ctaccatgaa aatgcggaag attttgccat gctttgggat acatatgagg acgaaactcc
    35821 tcactccatc gtgcatgagc tgactttctt tatcaaggag gctgacggtt cctttagtcg
    35881 ccacgatgaa gtacatgagg agaggaccta tgagatcttg acctatgata tcttgctgga
    35941 acaggctgga tttaagtcct tcaaactcta tgcagacttt gaggataagg agccaacaga
    36001 aactagcacc cgttggtttt ttgtggcgca gaagtaaatc aaatattgtt aatcttatgc
    36061 ttaggaggta agggaaaatg aatataccaa taccatttgg tgatattctt gaaaaagaag
    36121 taattaccaa tatacctaaa atttatcaaa agttaaagca aatttataac gacttacagt
    36181 ttaaaacaga agaagagtta ggtgttgttt atcaagaata tttacaattt acttataaaa
    36241 aatattccac tgtaaaaaca ttgttgtata aaaatgaagg gaaattttta tatgatttct
    36301 atgagcatgt ttatttagat gataataatt cagatttaat agaaacctct aacacagaat
    36361 tgatttttga aaaaacatct aacgttattt tgacaggaac gggtgggatt ggtaaatcaa
    36421 tgcttgtaaa gcatattttt atcaatcaag tacaacaagc tacatcaatt ccaattttta
    36481 ttgaattaaa atcacttaat gaatctgatt tctcagaaaa tgaattagtt gattttattt
    36541 accaagaggt tcaaaatcat catttaaatt tagaaaagaa atattttaaa gcgacattag
    36601 aggctggaag atatacaata atttttgatg gtttagatga ggttaatcct tcaaaacgtt
    36661 cttggttgga caaagaaatt aaagaatttg taacgttata caatagcaat agatatgttt
    36721 tgtcgtcaag accgtctgag gaatttattg gttggaatca gtttgctgag tatgagataa
    36781 aaaaattaaa tagagagcaa gcgttatcct taattgataa gttgaattat gatgagaaag
    36841 taaaaaggcg tttctacaga gaattaaagg atcatttata tgatactcat gaatcttttg
    36901 cttctatccc actcctatta acaattatgt taatgactta cgaagctggt gcttctattc
    36961 caaataattt aactgatttt tataatcagg ccttttatac attgtaccaa agacatgatg
    37021 catctaaatc aggatacaaa agagaactaa aagcaaaatt aactcctgaa gaatttcgaa
    37081 atatattagc ctacattggt ttaaaaacat tctttgaagg aaaagtagat ttcgatagaa
    37141 ctacacttga tgaaataatt actaaatatt gttttaaaaa taaccttgaa ttaaagacga
    37201 atgatatagt ttatgatgcg actcatagtg cttgtatgat gcttcaagaa ggcgttagtt
    37261 taaaattctc tcaccgttca ttccaagaat actttgctgc agtaggtgtt aatcagctag
    37321 atgataaact ccaaaaacag atactaatta agtggtctga agcagatagg aataatattg
    37381 tagcacataa aacttttatg aatgcacttt ttaaaataca gaaagaaagg acttacaaaa
    37441 atttatgtat tccaatcata gaaagaatgg atgaaaagta tagcagaatg ggggatatca
    37501 cagagaaaat tgttacgtgt ttcaattact ttatctgtag aaaagatagt agagaaaaca
    37561 aattagaatt gcacttttta ctaacaaagg aagttcactt ttattttagc ttgcaatttt
    37621 taatatttgc taatctaggt attgatatat tatcaataag tgattatgaa aatatagaaa
    37681 aattagagtc tgatatagta tcaaattgga agataaatga aagaaaatat tataacatgt
    37741 tgaacgatga tgaaaaaact ttaataaata agtggataaa tggctggtat tttagtagac
    37801 acaattactt aaaagaatgg tcaattaaat tcattgagga aacaactact caaaaacgga
    37861 gcctacagaa tataattgac tcaatttgat actaaagaag taggagatta ctatgaccat
    37921 cacgggtatt atcgcggagt tcaatccttt tcataatgga cacaaatacc tgctggatca
    37981 agcggagggg ctgaaaatcg tggctatgtc agggaatttc atgcagcgtg gagaacctgc
    38041 tatcgtggat aagtggacac gagcccagat ggcgctggaa aatggagcgg atctggtagt
    38101 ggaattgccc tttttagtca gcgttcaggc ggcagatttt ttcggtcaag gggccgtgga
    38161 tatcttagct cggttgggca tagatagcct cgcttttggg acagaagaag ttctagatta
    38221 tcaaaaaatc gctgacttat acacagagaa aggtgctgag atggagaaat ttgtggaaaa
    38281 tctgcctgat tccctttcct atccccagaa aacccaagct atgtggaagg aatttgctgg
    38341 tcttgatttt tcaggtaata cccccaatca tgttcttgct ctggcctatg ccaaggcagt
    38401 tgcaggacga aatatcaagc tgcatccgat tcagcgtcag ggggcaggtt accattctgt
    38461 gaataaagat gtggactttg cctcggcgac agccctccgt caacatcaga aggaccaaga
    38521 tttcttagaa cgctttatgc cttctgttgc cctatttgag caggccagta aggtgatctg
    38581 ggaagactat tttcccttgc tccgctatca aatcttgtca aatcccgacc taaccaccat
    38641 ctatcaggtc aatcaagaaa tggctgtgcg cattaaagaa gctattaaaa cagcccagtc
    38701 tgtagaagag ttggtcgagg cggttgcgac caaacgttac accaaggcgc gtgtcagacg
    38761 cctattgacc tatattttgg tgcaggctag agaaaatgtc ttgccagaag ccattcatgt
    38821 ccttggattt actgaaaaag gcaggcaaca tctcaagtct ctgaaaggac aggtcaatct
    38881 agtcagccga attggcaaag aaccttggga tgctatgacc caaaaagcag accagattta
    38941 ccaactagga aagccaagta tagcagagca aaattttgga agagtgccga ttagaataga
    39001 aacaagctaa gtctaccgaa aggtaggctt tttgagattt tttacgaata atactcttcg
    39061 aaaatcaaat tcaaatcgcg tcaacgtcgc cttgccgtac tcaagtacag cctgcggcta
    39121 gtttcctagt ttgctctttg attttcattg agtataaata gatagaaaag aaaatcttgt
    39181 acaagttcct gacaatttct ttcttttcgt gtataatagt ggaaaagagc taaaacgagg
    39241 tatggttatg gaagcagtcc tttactcaac attccgaaat catttaaagg actacatgaa
    39301 gaaggtaaat gatgaatttg agcctttgac ggtggtcaat aaaaatccag atgaggacat
    39361 tgtagttctt tcaaagagcg aatgggacag tattcaggaa accctgagaa tcgcccaaaa
    39421 taaggagtta tcagacaagg ttttgcgagg aatggctcaa gtccgtgctg gaagcactca
    39481 ggtccatgtg attgaggagt gatgaatgct actcaagttt acagaagatg cgtgggcaga
    39541 ttattgctac tggcaaaacc aagataaaaa aacactaaaa agaatcaata aattaatcaa
    39601 ggatattcaa cgcgatccat ttacaggaat aggaaaacca gagccactca aatatgatta
    39661 ccaaggagcc tggtcacggc gtattgatgc agaaaatcgc ttgatttata tgatggatgg
    39721 agatagcgtg gctttcttgt cctttaaaga tcattactaa gtctattgaa aggtaggctt
    39781 tttctcaagt ctctactaaa ctactatttc taaaaaacaa gtttattttg gcaaatgtgt
    39841 tccaaattcc ccaaaacata ttctatttta ggtttgtgaa aatcactttt ttatggtaga
    39901 atgtaaaaga atgtatgtca ttcggaataa caataaaatg aggtaaaaac atggagatca
    39961 tgtcgcttgc gattgctgtt tttgccgtca tcattggttt agtcattgga tatgtcagca
    40021 tctcagctaa gatgaaatca tctcatgaag ctgcagagtt gatgctttta aatgctgaac
    40081 aagaagcaac taatttacgt ggacaagctg agcgtgaagc ggatttactt gttaatgaag
    40141 ccaaacgtga aagcaagtct cttaaaaaag aagcactatt ggaggccaaa gaagaagcca
    40201 gaaaataccg tgaagaagtg gacgctgaat ttaaatcaga acgtcaagaa ctcaaacaaa
    40261 tcgaaagtcg tttgacagag agagctacta gccttgaccg taaggacgac aatttgacga
    40321 gtaaagaaca aacacttgaa caaaaagaac aaagtatttc tgatagagcg aaaaaccttg
    40381 atgcgcgtga agagcaatta gaggaagtcg aaagacaaaa agaagcagaa ctagagcgta
    40441 ttggtgctct gtctcaggca gaagcacgag atattatctt ggctcagaca gaggaaaact
    40501 tgaccaggga gattgccagt cgcattcgcg aagctgagca agaggtcaag gaacgttctg
    40561 acaaaatggc caaggacatc ttggttcaag ctatgcaacg tatcgctggt gaatatgtag
    40621 cggagtcaac aaactcaaca gttcatctgc cagacgatac tatgaaggga cgcattattg
    40681 gtcgtgaagg tcgtaacatt cgtacctttg aaagtttgac aggggtcgat gtgattatcg
    40741 acgatacacc agaagtggtg accttgtcag gatttgatcc gattcgtcgt gagattgccc
    40801 gtatgactat ggaaatgttg ctcaaagatg gtcgtataca tccagctcgt atcgaagagt
    40861 tggttgagaa aaaccgtcaa gagattgaca ataagattcg tgaatacggt gaggctgctg
    40921 cctatgaaat tggtgcgcca aaccttcatc cagacttgat gaagattatg ggacgtttgc
    40981 agttccgtac ttcatatgga caaaatgttt tgcgccattc gattgaggtt gctaagttgg
    41041 ctggtatcat ggcgagcgaa cttggtgaaa atgcggctct tgcccgtcgt gctggattcc
    41101 ttcacgatat cgggaaagcc attgaccatg aggttgaagg tagccacgtt gaaatcggta
    41161 tggaattggc ccgtaagtac aaggaacccc cagttgtggt gaatacgatt gctagtcacc
    41221 acggagatgt tgaagctgag agcgtgatag cagttatcgt cgctgcagca gatgccttga
    41281 gcgcagcccg tccaggtgct cgtagtgagt ctcttgaaag ctacatcaag cgtctccatg
    41341 atttggaaga aattgctaac ggctttgaag gagtgcaaac tagctttgcc cttcaagcag
    41401 gacgtgaaat tcgtatcatg gtcaatccag gaaaaatcaa ggacgacaaa gtcacaatct
    41461 tggctcacaa agttcgtaag aaaattgaaa acaatctcga ttatccagga aatatcaagg
    41521 taaccgtgat tcgcgagctt cgtgcagtag attatgctaa ataaataa
//
LOCUS       DBEROT010000016        40168 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.16, whole genome shotgun sequence.
ACCESSION   DBEROT010000016 DBEROT010000000
VERSION     DBEROT010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.16"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            552..1595
                     /locus_tag="ACL8CG_000982"
     CDS             552..1595
                     /locus_tag="ACL8CG_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGS1343596.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1763..3850
                     /gene="topA"
                     /locus_tag="ACL8CG_000983"
     CDS             1763..3850
                     /gene="topA"
                     /locus_tag="ACL8CG_000983"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGS1343597.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3956..4315
                     /locus_tag="ACL8CG_000984"
     CDS             3956..4315
                     /locus_tag="ACL8CG_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGS1343598.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4408..5040
                     /locus_tag="ACL8CG_000985"
     CDS             4408..5040
                     /locus_tag="ACL8CG_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGS1343599.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            5084..5740
                     /locus_tag="ACL8CG_000986"
     CDS             5084..5740
                     /locus_tag="ACL8CG_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGS1343600.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5810..6853
                     /locus_tag="ACL8CG_000987"
                     /pseudo
     CDS             5810..6853
                     /locus_tag="ACL8CG_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            6865..7901
                     /gene="leuB"
                     /locus_tag="ACL8CG_000988"
                     /pseudo
     CDS             6865..7901
                     /gene="leuB"
                     /locus_tag="ACL8CG_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            7898..8167
                     /locus_tag="ACL8CG_000989"
     CDS             7898..8167
                     /locus_tag="ACL8CG_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGS1343601.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8171..8530
                     /gene="leuD"
                     /locus_tag="ACL8CG_000990"
     CDS             8171..8530
                     /gene="leuD"
                     /locus_tag="ACL8CG_000990"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGS1343602.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8692..9260
                     /locus_tag="ACL8CG_000991"
                     /pseudo
     CDS             8692..9260
                     /locus_tag="ACL8CG_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004915491.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            9354..9419
                     /locus_tag="ACL8CG_000992"
                     /pseudo
     CDS             9354..9419
                     /locus_tag="ACL8CG_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9582..11513
                     /locus_tag="ACL8CG_000993"
     CDS             9582..11513
                     /locus_tag="ACL8CG_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGS1343603.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKV
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIGPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11500..12816
                     /locus_tag="ACL8CG_000994"
     CDS             11500..12816
                     /locus_tag="ACL8CG_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGS1343604.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKEWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12991..13977
                     /gene="guaC"
                     /locus_tag="ACL8CG_000995"
     CDS             12991..13977
                     /gene="guaC"
                     /locus_tag="ACL8CG_000995"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGS1343605.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPTKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            14041..14112
                     /locus_tag="ACL8CG_000996"
     tRNA            14041..14112
                     /locus_tag="ACL8CG_000996"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14074..14076,aa:Arg,seq:ccg)
     gene            14295..14993
                     /gene="rnc"
                     /locus_tag="ACL8CG_000997"
     CDS             14295..14993
                     /gene="rnc"
                     /locus_tag="ACL8CG_000997"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGS1343606.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14984..18523
                     /gene="smc"
                     /locus_tag="ACL8CG_000998"
     CDS             14984..18523
                     /gene="smc"
                     /locus_tag="ACL8CG_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGS1343607.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18520..19314
                     /locus_tag="ACL8CG_000999"
     CDS             18520..19314
                     /locus_tag="ACL8CG_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1343608.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYRGQDLYEATMSREFYLTTFEKLKTSPYV
                     DINKLLLTGKKGAYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGIIMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            19314..20132
                     /locus_tag="ACL8CG_001000"
     CDS             19314..20132
                     /locus_tag="ACL8CG_001000"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1343609.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            20136..21356
                     /gene="ftsY"
                     /locus_tag="ACL8CG_001001"
     CDS             20136..21356
                     /gene="ftsY"
                     /locus_tag="ACL8CG_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGS1343610.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQAEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(21400..22887)
                     /gene="zwf"
                     /locus_tag="ACL8CG_001002"
     CDS             complement(21400..22887)
                     /gene="zwf"
                     /locus_tag="ACL8CG_001002"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGS1343611.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(23036..23776)
                     /locus_tag="ACL8CG_001003"
     CDS             complement(23036..23776)
                     /locus_tag="ACL8CG_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1343612.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23776..25941)
                     /locus_tag="ACL8CG_001004"
     CDS             complement(23776..25941)
                     /locus_tag="ACL8CG_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS1343613.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQSTKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            26114..27067
                     /locus_tag="ACL8CG_001005"
     CDS             26114..27067
                     /locus_tag="ACL8CG_001005"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGS1343614.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            27144..29132
                     /gene="uvrB"
                     /locus_tag="ACL8CG_001006"
     CDS             27144..29132
                     /gene="uvrB"
                     /locus_tag="ACL8CG_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGS1343615.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMTYNEEHDIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKVLD"
     gene            29142..29705
                     /locus_tag="ACL8CG_001007"
     CDS             29142..29705
                     /locus_tag="ACL8CG_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1343616.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            29671..30159
                     /locus_tag="ACL8CG_001008"
     CDS             29671..30159
                     /locus_tag="ACL8CG_001008"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343617.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIDDLKVVGFISYGSFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LVKVALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            30232..30699
                     /locus_tag="ACL8CG_001009"
     CDS             30232..30699
                     /locus_tag="ACL8CG_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS1343618.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFTGTLQS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30696..31211)
                     /locus_tag="ACL8CG_001010"
     CDS             complement(30696..31211)
                     /locus_tag="ACL8CG_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGS1343619.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31223..31750)
                     /locus_tag="ACL8CG_001011"
     CDS             complement(31223..31750)
                     /locus_tag="ACL8CG_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1343620.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(32032..32595)
                     /locus_tag="ACL8CG_001012"
     CDS             complement(32032..32595)
                     /locus_tag="ACL8CG_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1343621.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(32579..33130)
                     /gene="coaC"
                     /locus_tag="ACL8CG_001013"
     CDS             complement(32579..33130)
                     /gene="coaC"
                     /locus_tag="ACL8CG_001013"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGS1343622.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(33142..33831)
                     /gene="coaB"
                     /locus_tag="ACL8CG_001014"
     CDS             complement(33142..33831)
                     /gene="coaB"
                     /locus_tag="ACL8CG_001014"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGS1343623.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            34061..35731
                     /locus_tag="ACL8CG_001015"
     CDS             34061..35731
                     /locus_tag="ACL8CG_001015"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGS1343624.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCALIDVPVELASVWADGVEGGVELAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQVVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            36059..37234
                     /gene="mutY"
                     /locus_tag="ACL8CG_001016"
     CDS             36059..37234
                     /gene="mutY"
                     /locus_tag="ACL8CG_001016"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGS1343625.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            37290..37994
                     /gene="yycF"
                     /locus_tag="ACL8CG_001017"
     CDS             37290..37994
                     /gene="yycF"
                     /locus_tag="ACL8CG_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGS1343626.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            37987..39336
                     /gene="vicK"
                     /locus_tag="ACL8CG_001018"
     CDS             37987..39336
                     /gene="vicK"
                     /locus_tag="ACL8CG_001018"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGS1343627.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     LLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            39338..40147
                     /locus_tag="ACL8CG_001019"
     CDS             39338..40147
                     /locus_tag="ACL8CG_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS1343628.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
BASE COUNT        12368 a         7110 c         8951 g        11739 t
ORIGIN      
        1 gaaataagat gtgaacaact ctatcaggaa agtcaaatta atttatagaa atattttagc
       61 agccaaggtg tactgttata gattcaatta cactataatt tagtgtaatt gagaaaggag
      121 aaatgattgt gattgatgtt ggctaggtta tgttcaatga ttcctaccgt ctcaaatctt
      181 gtcagtaagg aaaaataaat tcttcaaaag tagagattac aaggcttgtt taagaaagaa
      241 ttcaaagacc ttgacaaata aaaataaaat ggttattata agaaatggtc taaaatagat
      301 gatgatactt ttcgaaaatc tttttacgtc agctcagctt tgccttgctg tgttttgagc
      361 aagctacggt tagcttccga gtttgatttt catttactag aaatgaaact gatgagagat
      421 atcagtagac atttgagtca ggatattatg gaaaatgata aaaagagctc gtgagattgg
      481 catatcagac tactaaagta ttgagtttgt taggatttta gcgactagtt agctgggaaa
      541 ggaagatatt tgtgacaaat aataaactgt attcgttgat agaatttaga aataaaatat
      601 atgaagaatt agaactttcc agaagtgatt tagcgatttt actatgtgcc atgcttatcg
      661 cctctatcgg attaaatatg gattcgactc ccgtgattat tggagccatg ttaatctctc
      721 ctttgatgac acctattctg ggagtggggc tctctctagc tatatttgat tttaaattgt
      781 taagaaaatc ttttaaaata ttagctattc aaattcttgc cagtctaata gcttcaacac
      841 tttattttta tctttctccc atttcgtatg ctagttcgga gattgttgct agaacctctc
      901 cgactatttg ggatgttctc attgcttttg taggagggat agcaggtatt attggtgcta
      961 ggaaaaaaga gaccaataat attgttcctg gtgttgctat tgcaaccgcc ttgatgcctc
     1021 ctctttgtac agtaggttat gctattgctt ctgctaatct aaaatttatc ataggctcct
     1081 cttacctatt cctcatcaat tgtagcttta ttgtcattgc gacttatata ggtgttaggt
     1141 tgatgatggt taagaaacat tattttaaag ataatgaaga agactctaaa atgcgtagga
     1201 ttttgcttct agttgctgtt ttgctgatga ttccgagttt catctctgca acgactttag
     1261 tgagagaaac gttgaaaaaa gagtccctta agaaatttat atcagagcag tttcaggggt
     1321 ataatatttt gaaaaaaacc tattctaaaa agactcatac cctaaagcta accatttcag
     1381 gaaattattt gacagaagaa gaactcgata tgatttcaag taagagaggt gactatggtt
     1441 taagtgatgt ttctgttcaa gtttcacaat tgtctgattc agaacaactt agtaaggaag
     1501 agctggtgga gtatttcttc cagtatatca aggataagga agcaaaagaa aaggagaaag
     1561 ccaataaatt tgatacagag tctgaggagc aataatttct tgagaatagc tggtttctct
     1621 cgtgagtctt ctatgtatat caaaggaaga ctgaggtttt aagtataaaa cttttcttct
     1681 gtttatagta gctaagtctt gacagggttc aaaaaatggt ttacacttta taaagtttat
     1741 tactttgaaa aggtgtgata ctgtggctac ggcaacaaaa aagaaaaaat caacagttaa
     1801 aaaaaatcta gtcatcgtgg agtcgcctgc taaggccaag acgattgaaa aatatctagg
     1861 cagaaactac aaggtattag ccagtgtcgg gcatatccgt gatttgaaga aatccagtat
     1921 gtccgtcgat attgaaaata attatgaacc gcaatatatt aatatccgag gaaaaggccc
     1981 tcttatcaat gacttgaaaa aagaagctaa aaaagctaat aaagtttttc tcgcgagtga
     2041 cccggaccgt gaaggagaag cgatttcttg gcatttggcc catattctca acttggatga
     2101 aaatgatgcc aaccgtgtgg tcttcaatga aatcaccaag gatgcagtca aaaatgcttt
     2161 taaagaacct cgtaagatcg atatggactt ggtcgatgcc caacaagctc gtcggatctt
     2221 ggatcgcttg gtagggtatt cgatttcgcc tattttgtgg aagaaggtca agaagggctt
     2281 gtcagcaggt cgcgttcagt ccattgccct taaactcatc attgaccgtg aaaatgaaat
     2341 caatgccttc cagccagaag aatactggac agttgatgct gtctttaaaa agggaaccaa
     2401 acaatttcat gcttccttct atggagtaga tggtaaaaag atgaaactga ccagcaataa
     2461 cgaagtcaag gaagtcttgt ctcgtctgac gagtaaagac ttttcagtag atcaggtgga
     2521 taagaaagag cgtaagcgca atgctccttt accctatacc acttcatcta tgcagatgga
     2581 tgctgccaat aaaatcaatt tccgtactcg aaaaaccatg atggttgccc aacagctcta
     2641 tgaaggaatt aatatcggtt ctggtgttca aggtttgatt acctatatgc gtaccgattc
     2701 gactcgtatc agtcctgtag cgcaaaatga ggcggcaagc ttcattacgg atcgttttgg
     2761 tagcaagtat tctaagcacg gtagcaaggt caaaaacgca tcaggtgctc aggatgccca
     2821 tgaggctatt cgtccgtcga gtgtctttaa tacaccagaa agcatcgcta agtatctgga
     2881 caaggatcag ctcaagctat atacccttat ctggaatcgt tttgtggcta gccagatgac
     2941 agcggccgtt tttgatacca tggctgttaa attgtctcaa aatggagttc aatttgctgc
     3001 caatggtagt caggttaagt ttgatggtta tcttgccatt tataatgatt ctgacaagaa
     3061 taaaatgcta ccagatatgg ctgttggaga tgtggtcaaa caggttaata gcaaaccaga
     3121 gcaacatttc acccaaccgc ctgcccgtta ttctgaagca acactgatta aaaccttaga
     3181 ggaaaatggg gttggacgtc catcaaccta tgcgccaacc attgaaacca ttcagaaacg
     3241 ttattatgtt cgcctggcag ccaaacgttt tgaaccgaca gagttgggag aaattgtcaa
     3301 taagctcatc gttgaatatt tcccagatat cgtaaacgtg accttcacag ctgaaatgga
     3361 aggtaaactg gatgatgtcg aagttggaaa agagcagtgg cgacgggtca ttgatgcctt
     3421 ttacaaacca ttctctaaag aagttgccaa ggctgaagaa gaaatggaaa aaatccagat
     3481 taaggatgaa ccagctggat ttgactgtga agtgtgtggc agtccaatgg tcattaaact
     3541 tggtcgtttt ggtaaattct acgcttgtag caatttccca gattgccgtc atacccaagc
     3601 aatcgtgaaa gagattggtg ttgagtgtcc aagctgtcat cagggacaaa ttattgagcg
     3661 aaaaaccaag cgtaatcgcc tcttctatgg ttgcaatcgc tatccagaat gtgaatttac
     3721 ctcttgggac aagcctgttg gtcgtgactg tccaaaatgt ggcaacttcc tcatggagaa
     3781 aaaagtccgt ggtggtggca agcaggttgt ttgtagcaaa ggcgactacg aggaagaaaa
     3841 gattaaataa gaggaggggc ccgaaagtaa atttcaggct ccttttggtt agaacttgac
     3901 aaaatacatc attttatgcg aaactagaag aagattattt taactaggag aagttatgcg
     3961 tcttatctat ctgataattg gttttttatc actggccttg gctattgttg gggttgtttt
     4021 acccttgttg ccgacaacgc ctttcctttt gttgtctatt gcttgtttct ccagaagttc
     4081 caagcgtttc gaagactggc tttatcatac taagctctat caaacatatg tagctgattt
     4141 tcgcgagact aagtctatta cgcgtgaacg aaagaaaaaa atcatcgtct ctatctacgt
     4201 cttgatggga atttctattt attttgcacc tcttttacca gtcaaaatcg gtctgggtgc
     4261 tttgaccatc tttatcactt attatctttt caaggtcatt ccagacaaag aatagttaaa
     4321 acagtagtta tttgccttga taaaattgaa agcatattca taataatatg atataataaa
     4381 tttgaagtaa tattcaagga gaatcaaatg atttacgaat tttgtgctga aaatgtgact
     4441 ttacttgaaa aagcgatgca ggctggagct cgtcggattg aactctgtga taatctagca
     4501 gttggtggga caacacccag ctatggagtg actaaggcag cggttgaact ggcagctaac
     4561 tacgatacaa ccatcatgac catgattcgg ccacgtggtg gtgactttgt ctataatgac
     4621 ctagaaattg ctatcatgct agaagacatt cgtttgactg ctcaggctgg aagtcaaggg
     4681 gttgtatttg gaactttaac tgctgataaa aagttggata agcctaatct ggaaaagtta
     4741 attgctgcat caaaaggaat ggaaattgtc tttcacatgg cctttgatga actaagtgat
     4801 gaagatcaac cggaagctat tgactggctc agtcaagccg gtgtcactcg tatcctaact
     4861 cgtgctggtg tgtctggcga ctccttagaa aaacgttttg ttcactatca cagaattttg
     4921 gagtacgcta aaggtaaaat tgaaattcta ccaggtgggg ggattgacct tgaaaaccgt
     4981 caaaccttta tcgaccaggt gggggtaaca caattgcatg gtactaaggt tgttttttaa
     5041 aaaatagaaa ggaactgcta gctttgggta gcagttttca cttatgtttg aaatttttaa
     5101 atcctatcaa tttaatcaag aaaaggctca tgattatggt tttatagaaa atagcgaagt
     5161 ctggacatat agttgccaga ttttgcaagg tgactttgtc atgactgtgt ccatcactgc
     5221 tgataatgtg aactttcaag tctttgacca agagactggt gacctctatc ctcacgttca
     5281 tatggaaagc atgaggggaa gttttgtcgg aaatgtccgt gaggcttgtc tggagattct
     5341 ttaccagatt cggaaggctt gttttgatgt gcaagatttt atctgtcatc agactaagcg
     5401 tatcatgact caagttcagg aaaagtatgg aaaccagttg gagtatctgt gggaaaaatc
     5461 gcctgataca gctgtattgc gccatgaagg caatcaaaag tggtatgccg tcttgatgaa
     5521 aatctcttgg aataagctgg aaaagggcag agaaggacaa gtggaagcag tcaacctcaa
     5581 gcatgaccaa gtagctaatt tgctttcaca aaaggggatt tatccagcct tccatatgag
     5641 caagcgctac tggattagtg tgtcccttga tgatacttta tcagatgaag aagtactgga
     5701 attgatagaa aaaagttgga acttaacctc taaaaaatga aatattttaa taattttcat
     5761 gaactttcaa ttggctaaat attctttact gaagaaattt tcagaaaata taggatttac
     5821 cacaccagag gaatatggtg ccatcttcaa atacctgatt gagaatgtca agacggatcg
     5881 tcagatcatc tattcgcctc actgtcatga tgacctcgga atagcagtgg caaatagcct
     5941 tgctgctgtc aagaatggtg caggacgtgt tgaagagact atcaatggta ttagggagcg
     6001 agctggaaat gctgctttgg aagaaattgc agtggctctc aatattcgcc aagattacta
     6061 ccaagtagaa accagtattg tcctaactga gaccatcaat acgtcagaaa tggtttctcg
     6121 cttccctggt attccagttc ctaaaaacaa agccgtcgtt ggtggcaata ccttctccca
     6181 cgaatctggt attcaccaag atggagtcct taaaaatcct ctcacttatg agaacatcac
     6241 acctgaattg gttggtgtta agattccgct tggaaaatta tctggtcgcc atgcttttgt
     6301 tgagaaactg agagaattgg ccctagattt tacagaagag gatatcaaac cactctttgc
     6361 taagttcaag gcactggccg ataagaagca agaaatcaca gatgcagata ttcgagcttt
     6421 ggtagctgga accatggttg aaaatccaga aggcttccac tttgatgatt tacaacttca
     6481 aactcatgca gataatgaca ttgaagcgct cgttagccta gccaatatgg atggtgagaa
     6541 agtcgaattt aatgcgacag ggcaaggttc cgttgaagca atctttaacg ctatcgataa
     6601 gttctttaat caatctgttc gtttggtgtc ctacactatc gatgcgataa cagatggaat
     6661 cgatgcccag gatcgggttt tggtcactgt tgaaaacaga gatacagaaa ccatctttaa
     6721 tgcaacaggg cttgattttg atgtgttgaa ggcttctgct attgtctata taaacgctaa
     6781 tacctttgtt caaaaagaga atgcaggtga gatgggacgc agtgtttctt accacgatat
     6841 gcctagtgtg taaaggagaa ggctatggca aagaaaatag tagctctagt aggagacgga
     6901 attggcccag aaatcatgga ggctggttta gaagttctgg aggctctagc tgaaaaacag
     6961 gttttgacta tgagattgac agacgaccgt tcggaggtgc agatattgat gcagcaggac
     7021 ctcccttacc tgatgaaacc cttaaggcaa gtagggaagc agatgctatc ctactagcag
     7081 ctatcggtag tcctcagtat gatggagcag cggttcgccc tgaacaaggc ctgatggctc
     7141 tccgtaagga actcaatctt tacgctaata ttcgtcctgt aaaaatcttt gacagtctca
     7201 agtatttgtc accacttaaa ccggaacgaa tttctggtgt agactttgtc gtggtgcgtg
     7261 aattgacagg cgagatttac tttggagatc atattcttga agagcgcaaa gcgcgtgata
     7321 tcaacgacta tagctatgag gaagtggagc ggattattcg caaagccttt gaaattgcaa
     7381 gaaatcgcag aaaaatcgtt actagtatcg ataagcaaaa tgttctagcg acctcaaaac
     7441 tctggcggaa agtagctgag gaagtcgcac aggatttccc agatgtaacc ttggaacacc
     7501 agctggtaga ctcagctgct atgcttatga ttaccaatcc tgctaagttt gatgttattg
     7561 taacggagaa tctttttgga gatattttat ctgatgaatc aagcgtctta tctggtacac
     7621 ttggggttat gccatcagcc agtcattctg aaaatggacc aagtctctat gaacctattc
     7681 acggttcagc acctgatatt gcaggtcaag gaattgccaa tcctatttcc atgattttat
     7741 cagtttccat gatgttgaga gatagtttcg gacgttatga ggatgcagag cgtatcaaac
     7801 gtgctgttga gacaagtctg gcggcaggaa ttttaacgag agatatagga ggtcaggctt
     7861 caacaaagga aatgacggaa gctattattg caaggttatg aagttagacg aaaaaattac
     7921 tctagtcctt ttgatttgga atgtcatcat tttcttgatt tatggcattg acaaattcaa
     7981 ggcaagaaga agagcttggc gcatccaaga gaaaatctta ctcattttag cccttacttg
     8041 tggtggtttt ggggcctggt tagctggaat cacttttcac cacaagactc gaaaatggta
     8101 ctttaaaaca gtttggtttc ttgggatggt gaccacacta gtagccttat attttatttg
     8161 gaggtaatgg atggcagggt cttcgaggga acacgctgct tgggttctag cggactatgg
     8221 ctttaaggtc gtgattgcag gatctttcgg tgacattcat tacaataatg aactcaataa
     8281 tggcctgttg ccaatcgttc agcctaggga ggttagagaa aagctagccc aactcaaacc
     8341 gaccgaccaa gtaactgtag acttggaaca acagaaaatt atctcaccag ttgaagaatt
     8401 caccttcgag atagatagcg agtggaaaca taaactccta aatagtttgg atgatatcgg
     8461 tattaccttg cagtatgaag agttgattgc tgcttatgaa aaacaacgac cagcctactg
     8521 gcaggattag aaaaaataga aaaggaaata tagtaaactg aaataagatg taaacaaatg
     8581 aattagagct taacatccat ttccagcaat tttttagaaa ctacagtgga ctattctgga
     8641 ttcaacacat tataaaatta tgacaaaaca cattcacaag aaggctacga cattttaaaa
     8701 ggtgagggcg gatgtatcat ttgccctact aaagttggtt acattatcat gaccagtgac
     8761 aaggcaggac ttgagcgtaa gttcgcagcc aaagagcgta agcgtaacaa accaggtgtt
     8821 gttctctgcg gtagcatgga tgaactttgc gctttagcgc aactcaaccc agaaattgaa
     8881 gcattctact aaaaacattg ggatgaagat attcttcttg gttgtatcct tccttggaaa
     8941 ccagaagcct ttgaaaaact caaagcatac ggggatggcc gtgaagaact tatgactgat
     9001 gtacgtggta ctagctgttt tgttatcaag tttggaaaag caggtgaaca attggctgcc
     9061 aagctttggg aagaaggtaa aatggtctac gcgtcatctg cttcaatgac aaaacgattg
     9121 aaactcgcta tgagcaaggt gtaatggtgt ctatggtcga taaggacggc aaactcatcc
     9181 cagaacaagg aggagcacgt tcaacttcac cagctccagt tgtgatccgt aaagggcttg
     9241 acattgatat agtaaaatga agtaagagca ggacaaatta atcaggacag tcaaatcgat
     9301 ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatccac tataaaatca
     9361 tgatgcacct gtcagatact tttaactcat gggactaccg tcaggttgag tattattagg
     9421 atagagaaga agtctagtgt taaggacatt acagctcata atactaggct tttttataga
     9481 aattcttttc tttttctata ggatatggta ttctatgtag aaaatatatg ttaataagta
     9541 atgccaatat ttaaacatca ttagtaaaag gagttagatt gatgaataaa agaaaagtta
     9601 gtttagaaga tttttataaa tggtatagtc taaataaaga agagttatta aataaggcaa
     9661 ctgttggtga aaagtttaat gataaattaa aagaagagtt tctccaggaa tggcctttgg
     9721 ataggatttt aacaatgtca atcgatgaat atgtaatagg aaagggacag caaaataagt
     9781 ctttatgcta cgctcttgag aagggaaaat acaaaaatct atttcttgga atttctggtg
     9841 gctcagcttc aaaatttggt atttattgga ataaaaaaac aaacaaatat aaagatcaag
     9901 ctaataatga gatttcagag ttggatcagc gattttcaaa attaaaatca gatttgtatg
     9961 aaattatcaa agaaggtatt cgttttaact ttgaaaatcc tatttttgat atgaaaagat
    10021 caacaaatga atttattggt cgttctgcta tggtgacaaa attactttgt atctattctg
    10081 agggagatcc tttctttggt gtaaatatta atagtcagaa agaattttgg aaccactttg
    10141 tttctcagac aaatcaaggt ggaccttatc tgcaaaatca taaaataatt gaactggtgt
    10201 ccaaaactta tcctgagttg gagccatcga aagtaggaac tatgcttttt gagtattcta
    10261 agctttttat ggaaaataag gaagacaata gtacaatgga ttcatcaaac aattttcgtc
    10321 atcaattaac tcaatctcta ttaaagtctc caaaccttat ccttcgtggt gctcctggca
    10381 caggaaagac ttatcttgct aaagaaattg ccaaagaatt aacggatggc aacgaagacc
    10441 aaatcggatt tgtacaattt cacccatcat atgattatac ggattttgta gaaggtttaa
    10501 gaccagtatc aaatggggat ggagctattg agtttaggct acaggacggt atttttaaag
    10561 atttttgtca gaaagcaaaa gaaacccaat tgattggagg acaagataat tttgatgagg
    10621 cttgggattc ttacttagaa tatataaatg ttgctgaaga aaaagaatat ataacaaaaa
    10681 catcttactt atctgttaat agtagacaaa atttgtcagt aaattatgat agtggtgttc
    10741 caggatggtc actacctagc aaatatgttt acgagttgta taaagataaa aattataata
    10801 agcaagaata ctacaaaagt ggtggaaaaa ctgtcctaga aacattgaga aagagatttg
    10861 gtttgaaaga ctatgtttcc ccaacagaaa ttgatactga taagaaattc gtcttcatca
    10921 tcgatgaaat caatcgtggg gagatttcta agatttttgg cgaactcttt ttctctatcg
    10981 gccctggcta tcgtggtgaa aaaggaagtg tttctaccca atatgcaaat ctacacgaaa
    11041 ctgatgaaaa gttctatatc cccgaaaatg tttacatcat cggaactatg aatgatattg
    11101 atcgttcagt ggataccttt gattttgcta tgcgtcgtcg ttttcgtttt gttgaagtta
    11161 ctgccgaggg tcaagttggc atgttggata aagagctgaa tatccatgca gaagaagcaa
    11221 aaattcgtct aagaaacttg aacgctgcta tcgaaaatgt tcaggaatta aacagtcatt
    11281 atcatattgg accaagttat tttcttaagt tgaaggatgt agattttgac tatgaattac
    11341 tctggtctga ttatattaag cctctcctag aagactactt gcgaggttct tatgatgagg
    11401 ttgaaacttt ggaaactttg aaaaaagcat ttgaactgac aaataatgag caaaaagatc
    11461 aggcagtagc tgatgacaat gaaggtgatg aaaacgatga tgcggattac tgataatcaa
    11521 cacaagatta ttaaagaaaa atttgttgaa gaatatccta aactaagcaa tcttctttta
    11581 gacagaacct tggaaagttt atcccaagat gaacgtattt tcatttttcc aaatgatttg
    11641 actcatactc ctgatttgga taaggaccaa aagatttttg aaacagtcaa tcagaaaatc
    11701 aagacaggga acgtgattgg ttttcttgga tatggtcagg aaagattaac gatttcctca
    11761 cgattttctg atgagagtaa tgaccatttt ttgcattatc tcttaaacaa ggttcttcat
    11821 atcaatctca ctagtttaga tgttgctttg tctcgtgaag agaggcttta tcaacttttg
    11881 gtgtatctct ttcccaagta tctacaagct gctattcgaa aaggtcttta taaggaatat
    11941 catcgatttt ctcataacga cagtaatgtt aagggagtga ttgatgtaag aagccatctc
    12001 aagaaaaatc ttcctttcac gggaaatatt gcctacgcaa cgagagagtt cacctatgat
    12061 aatcccctca tgcagttggt ccgtcacact attgaataca ttaagaatca gaaaagcatt
    12121 ggtcaagggg tactagataa tctctcaact agtcgtgaaa acgtatctga aatcgtgcgt
    12181 gtaacgccct cttataaact agctgatcgt gctaagatta ttcggggaaa tcaatctaaa
    12241 cctatacgtc atgcatactt tcacgagtac agaaacttac aagaactttg tctgatgatc
    12301 ctaaaccaag aaaagcacgg tttagggtat caagatcaaa aaatctatgg tattctcttt
    12361 gatgttgcct ggctttggga agagtatgtt tacaccttgt tgccaaaagg ttttgtacat
    12421 cccagaaata aggataagac ggatggaatt tcagtatttt ctgttgggaa acgaaaagta
    12481 tatccagatt tttatgacag agaacgaaag attgttctag atgcaaaata taaaaaactg
    12541 gaattgactg aaaaaggaat caaccgtgag gacttattcc agctgatttc ctattcttat
    12601 attttaaaag ctgagaaggc tggactgatt tttcctagta tggagcagtc agtaaatagt
    12661 gaaataggaa aagtagctgg ctatggagct caattgaagg agtggtctat tcgaatccct
    12721 cagaatgcct cattctatag tacattttgt aaaatgatgg aaaattcaga agaaaatttt
    12781 aaagcgatta ttgatgaaga agtggggaga aaataatttc ccctctttct tttattttta
    12841 acacaagtaa aacccgaacg atatatttta attcataaaa taatttgaca aaaactgtac
    12901 tttggtttat aataaattaa ggaaacgtcg gaaaaggcgt agtgatgcaa gagcataggt
    12961 aggtcattac aaaagaaacg agacatcgat atgttaaatg aatttccaat ttttgattac
    13021 gaagatattc aattgattcc aaataaatgt gtcattaaaa gccgtgcaga agcggataca
    13081 agtgtcactt taggaaatca cacctttaaa ctacctgttg tgccagcgaa tatgcagacg
    13141 attttggatg aaaatgtagc agagcaactg gctaaaggtg gttacttcta cattatgcac
    13201 cgttttgatg aggcaggacg cattcctttt attaaacgaa tgcacaatca agggctcatt
    13261 gcttccatat ctgtcggtgt taaggactat gagtatgatt tcgttagaca gctcaagact
    13321 gatgctcctg agtatatcac tattgatatt gctcatggtc atgcggatag cgtgatttct
    13381 atgattcaac acatcaagaa agaattgcca gatacctttg tcattgctgg aaatgtggga
    13441 acaccagaag ctgtgcgtga attggaaaat gctggtgcgg atgctactaa ggtcggaatc
    13501 ggtcctggta aggtttgtat caccaaggtt aagactggtt ttggtacagg tggttggcag
    13561 ttggctgctc tacgctggtg tgccaaggct gcgcgtaaac cgattatcgc tgatggagga
    13621 attcgtactc acggtgatat tgccaagtct atccgcttcg gtgctagcat gatcatgatt
    13681 ggttccctct ttgcaggaca tattgaaagt ccagggaaaa cgattgaagt cgatggtgaa
    13741 cagttcaaag aatattatgg ttcagcctca caatatcaaa aaggtgctta caaaaatgtg
    13801 gaaggcaaac gtatcttgct tcctactaaa ggtcatctgc aagacacttt aactgagatg
    13861 gaacaagacc ttcaaagtgc tatttcttat gcaggtggac gtcaggttgc tgaccttaaa
    13921 cacgttgatt atgtgatcgt gaaaaactcc atctggaatg gggatgcttc ccactaagac
    13981 ggggtctttg actaaaaaac ttgttattag agcaaatttc tgttataata aaacaagttt
    14041 ccacccttag tgtaatggat atcacgtaag attccggttc ttgagatggg ggttcgattc
    14101 cctcagggtg gatgtaaaca ttctaaaaag cctttaatag ggcttttttc tttacactac
    14161 tctaaatttg ccactaaaac tgagaatctc tgtctaaaga attcccaaat gctttccagt
    14221 cccgttttag agtgactcag ggggcttttt ttgatataat aaaaaggact gttatcagtt
    14281 agaaagaggt tggtatgaaa gaattacaaa ctgtactaaa gaaccatttt gcaatcgaat
    14341 ttacagacaa aaagttactg gaaactgcct ttactcatac gagttatgcc aatgagcacc
    14401 gcctcttaaa aatttcacat aatgaacgct tggaattttt aggagacgct gttctacagt
    14461 tattgatttc agaatatctg tataaaaaat atcctaaaaa gcctgaaggt gacctatcaa
    14521 aactccgtgc tatgattgtc cgtgaggaga gtttagctgg ttttgcgcgt gattgccagt
    14581 ttgaccagtt tatcaagttg ggtaaagggg aagaaaaatc tggtggtcgc aatcgtgaca
    14641 ccattcttgg tgatgccttt gaagcctttc ttggtgccct tcttttggat aaggatgtgg
    14701 ccaaggtcaa ggaatttatc tatcaagtca tgattcctaa ggttgaagca ggcgaatttg
    14761 agatgattac agactataaa acccatctcc aagagttact tcaggtcaat ggtgatgtgg
    14821 ctattcgtta tcaggtgatt tctgaaacag ggcctgctca cgataaggtc tttgatgtag
    14881 aagttcttgt tgaaggtaag agcatcggtc aaggccaagg tcgttctaag aaattagcag
    14941 agcaggaagc tgccaaaaat gccgttgaga aggggctgga ttcatgtatt taaaggaaat
    15001 cgaaattcag gggttcaagt cttttgctga taagaccaag gtcgtttttg accaaggtgt
    15061 gacggcagtt gttggaccca atggatctgg aaagtccaat attacagaaa gtctgcgttg
    15121 ggctttgggg gagtctagtg tcaagagtct ccgtgggggc aagatgccgg atgtcatctt
    15181 tgctggaaca gaaagtcgca aaccgctcaa ttatgcttct gtagttgtga ctctggataa
    15241 tcatgacgga tttatcaagg atgcaggtca agaaatcagg gtggaacgcc atatctatcg
    15301 tagtggagat agcgaataca agattgacgg caagaaagtc cgtctgcgtg atattcatga
    15361 ccttttcttg gatacaggtt tgggacgaga ttccttctct attatttccc aagggaaggt
    15421 tgaggagatt tttaattcca agtctgagga acgacgagct atttttgaag aagctgctgg
    15481 agttttaaaa tacaagactc gcagaaaaga aaccgagagt aaactgcagc aaactcagga
    15541 taatctggac cgcttagagg acattatcta cgagttggat aatcaaatca agcctcttga
    15601 gaagcaagct gagaatgccc gtaaatttct agacttagaa ggtcaacgca aggctattta
    15661 cttggatgta ttggttgctc aaatcaagga aaataaggca gaactagagt cgacagaaga
    15721 agagttggct caggttcaag aactcttgat gagttattac caaaagcgtg aaaaattaga
    15781 agaagaaaat caaactctta aaaagcaacg ccaagattta caggctgaaa tggccaaaga
    15841 ccaaggcagt ttgatggact tgactagtct gattagtgat ttagaaagaa aattagccct
    15901 atcgaaactg gagtctgagc aagtggcctt gaatcaacag gaggcacaag ctcgtttggc
    15961 tgctttggag gataagagaa attcactcag caaagaaaag tctgataaag aaagctcttt
    16021 agctctgtta gagggaaatc tagtccaaaa taatcaaaaa ctcaatcgtt tagaagctga
    16081 attgctggct ttctcagacg atcctgatca gatgattgag ctcttacgtg aacgctttgt
    16141 agctctttta caagaagaag cggatgtctc aaaccagttg acccgtattg agaatgagtt
    16201 ggaaaatagt cgtcagcttt ctcaaaaaca agcagatcaa ctagaaaagc tgaaagagca
    16261 attagctata gctaaagaga aggctagtca gcaaaaggaa gagcttgaaa ctgccaagga
    16321 gcaggttcag aaattattgg ctgactacca agctattgcc aaggagcaag aggagcagaa
    16381 aacttcctat caagctcaac aaagccaact ctttgaccgt ctggataatc tcaaaaacaa
    16441 gcaggccaga gctcaaagtt tggaaaatat cctgagaaat catagtaact tttatgcagg
    16501 tgttaagagt gttctccaag aaaaagatcg cctaggtggg attattggtg cagtcagtga
    16561 gcatctgacc tttgatatgc attatcaaac tgccctagaa attgcgcttg gagcgagtag
    16621 ccaacatatc atcgtagaag atgaagagtc ggcaaccaag gctattgact tccttaaacg
    16681 gaacagagcc ggtcgtgcaa cctttcttcc tttgaccact atcaaggcgc gtacgatttc
    16741 tagtcagaac caagatgcta tcactgtaag tccaggtttc cttgggatgg cagatgagtt
    16801 ggtgactttt gatactagac tggaagccat tttcaagaac ttgctagcta cgacggctat
    16861 ctttgatgcc gtagaacatg cgcgtgcagc agctcgccaa gttcgttatc aggttcgtat
    16921 ggtgacattg gatgggacag aattacgcac gggtggttcc tatgcgggtg gtgccaatcg
    16981 ccaaaataac agtattttca tcaagccaga actggagcaa ttacaaaaag aaattgctgc
    17041 agatgaagca agcttgcgtt cagaagaagc ggctttgaag accttacaag accagatggc
    17101 tacattgaca gaaagattag aagtcatcaa atctcaagga gaacaggcac gtattcagga
    17161 gcaaggcttg tccctcgctt atcagcaaac tagtcagcaa gttgaagaac tggaaactct
    17221 ttggaaactc caagaagagg aaatagatcg tctttccgag ggagattggc aagcggataa
    17281 ggaaaaatgc caagatcgtc ttgctgcaat cgccagtgac aagcaaaatc tggaagctga
    17341 gattgaagag attaagtcta acaaaaatgc catccaagaa cgctatcaaa acttgcagga
    17401 agagctagcg caagctcgtt tgcttaagac agaactgcaa gggcaaaaac gttatgaagt
    17461 tgctgatatt gaacgcttag gcaaggaatt ggacaatctt gattttgaac aagaggaaat
    17521 ccagcgcctt cttcaagaaa aggttgataa tcttgagaag gttgatacag aattgctcag
    17581 tcaacaggcg gaagaagcca aaactcagaa aacaaatctc caacaaggtt tgattcgcaa
    17641 gcagtttgag ttggatgata ttgaaggtca actggatgat attgctagtc atttggatca
    17701 ggctcgccaa cagaatgaag agtggattcg caagcaaaca cgtgctgaag ccaagaaaga
    17761 aaaggttagc gagcgcttgc gctatttaca aagtcaatta acagaccaat atcagattag
    17821 ctatactgaa gctctagaaa aggcgcatga attggaaaac ctcaatctgg cagagcaaga
    17881 ggtgcaggat ttagagaaag ctattcgctc actggggcct gtcaatatag aagctattga
    17941 ccagtacgaa gaagttcaca atcgtctgga tttcctaaat agccaacgag atgatatttt
    18001 gtcagcgaaa aatctgctcc ttgagaccat tacagagatg aatgatgagg tcaaagatcg
    18061 ctttaaatca acctttgagg ccattcgtga atcctttaaa gtgaccttca aacagatgtt
    18121 tggaggaggt caggcagact taatcttgac tgagggagac ttgttgacag ctggggttga
    18181 gatttctgtt caacctccag gtaagaaaat ccagtcgctt aacctcatga gtggtggtga
    18241 aaaagcctta tcagctcttg ctttgctttt ttctatcatt cgagttaaga ctatcccatt
    18301 tgtcatcttg gatgaggtag aggccgcgct ggacgaagcc aatgttaaac gttttgggga
    18361 ttacctcaat cgatttgaca aggacagcca gtttatcgtc gtaacccacc gtaagggaac
    18421 catggcagcg gctgattcta tctatggagt gaccatgcaa gaatcggggg tctcaaaaat
    18481 tgtttcggtt aagttaaaag atttagaaag tattgaagga tgacaattaa actagtagca
    18541 acggatatgg acggaacctt cctagatggg aatggacgct ttgatatgga ccgcctcaag
    18601 tctctcttag cttcctacaa ggaaaaaggg atttactttg cggtggcttc ggggcgcgga
    18661 tttctgtctc tagaaaaatt atttgctgat gttcgtgatg acattatttt tatcgcagaa
    18721 aatggcagtt tggtagagta tcgaggtcaa gacttgtatg aagcgaccat gtctcgtgag
    18781 ttttatttga cgacttttga aaagctgaaa acttcacctt atgtagatat caataaattg
    18841 ctcttgacgg ggaaaaaggg agcttatgtt ctagatacgg ttgatgagac ctatttgaaa
    18901 gtgagtcagc actataatga aaatatccaa aaagtagcga gtctggaaga tattacagat
    18961 gacattttca aatttacgac caacttcaca gaagaaacgc ttgaagctgg ggaggcttgg
    19021 gtcaatgaaa atgtccctgg tgttaaggcc atgacaactg gctttgaatc cattgatatt
    19081 gttctggact atgtcgataa gggtgtggcc attgttgaat tggctaaaaa acttggcatc
    19141 ataatggatc aggttatggc ttttggagac aatctaaatg atttgcatat gatgcaggtt
    19201 gtgggacatc ctgtagctcc tgaaaatgca cgacctgaaa ttttagaatt agcaaagact
    19261 gtgattggtc accataagga ccagtcggtt atagcttata tggagggctt ataatggcag
    19321 atataaaatt aatcgcattg gacttggacg gtaccttgct gactactgat aaaaggctga
    19381 cggatcgcac caaggcaact ttgaaagctg cgagtgatcg tggtatcaag gtcgtattga
    19441 caactggtcg tcccttaaaa gccatggact tctttctcca tgagttaggg actgacggcc
    19501 atgaagatga gtataccatt acttttaatg gtggattagt tcagaaaaat acaggagaaa
    19561 tccttgataa aacagtcttt tcatatgatg atgtggcacg tttgtatgag gaaacagaga
    19621 aattatcact gcctcttgat gccatctcag aaggaacagt ttatcaaatc caatcggacc
    19681 aagaaagtct ttatgccaaa ttcaatccag ctttgacttt tgttccagtt gactttgaag
    19741 acctgtctag tcaaatgacc tacaacaaat gcgtgactgc ctttgctcaa gaacccttgg
    19801 atgcagccat tcagaagatt tctccagaat tgtttgacca atatgaaatc tttaaatcac
    19861 gtgaaatgtt gctagaatgg tcaccaaaga atgttcataa agcaacaggt ttggcaaaac
    19921 taattagcca tcttggaatt gatcaaagtc aagtgatggc ctgtggtgac gaggccaatg
    19981 acctctctat gattgaatgg gcagggctcg gtgttgccat gcaaaacgct gttcctgaag
    20041 taaaggcagc cgcaaatgta gtgacgccga tgaccaacga tgaggaagct gtcgcctggg
    20101 ctatcgaaga atatgtgcta aaggagaact aagatatggg attatttgac cgtctattcg
    20161 gaaaaaaaga agaacctaaa atcgaagaag ttgtaaaaga agctctggaa aatcttgatt
    20221 tgtctgaaga tgttgatcct accttcacag aagttgaaga agtttctcaa gaagaagctg
    20281 tgcttgaaga aagtcaggat tcagagccag ctgtaggggt ttctcaagaa gaaatagaag
    20341 aattaccaga ggaagagaag cttgagcacg aaggaactat agaagaaaat aattctgaag
    20401 ttcttgaagc agaaaggcct caagcagaag aaaccgttca ggaaaaatat gaccgcagtc
    20461 ttaagaaaac tcgtacaggt ttcggtgccc gcttgaatgc cttctttgct aacttccgct
    20521 ctgttgacga agaatttttt gaggaactgg aagaactgct gattatgagt gatgttggtg
    20581 tccaagtcgc ttctaactta acggaggaac tacgttacga agccaagctt gaaaatgcca
    20641 agaaacctga tgcacttcgt cgtgtcatca ttgagaaatt ggttgagctt tatgaaaagg
    20701 atggtagcta cgatgaaagc atccacttcc aagataactt gacagttatg ctctttgttg
    20761 gtgtgaatgg tgttgggaaa acaacttcta tcggaaaact agcccaccgc tacaaacgaa
    20821 ctggtaagaa ggtcatgctg gttgcagcag ataccttccg tgcgggtgca gtagctcagc
    20881 tagctgaatg gggccgacga gtagatgttc cagtagtaac tggacctgaa aaagctgatc
    20941 cagccagcgt ggtctttgat ggtatggaac gtgccgtggc tgaaggtatc gatattctca
    21001 tgattgatac tgctggtcgt ctgcaaaata aggataacct tatggctgag ttggaaaaga
    21061 ttggtcgtat tatcaaacgt gttgtgccag aagcaccaca tgaaaccttc ttggcacttg
    21121 atgcatcaac aggtcaaaat gccctagtac aggccaaaga attttcgaaa atcacacctt
    21181 taacgggaat tgttttgact aagattgatg gaactgctcg aggaggtgtg gttctagcca
    21241 ttcgtgaaga actcaatatt cctgtaaaat tgattggttt tggtgaaaaa atcgatgata
    21301 ttggagagtt taactcagaa aactttatga aaggtctctt ggaaggctta atctaatcag
    21361 aagcaaaaat cctgcaaggt acaaacttgc aggatttttt tattcgaaac gaccatcttg
    21421 acgataggcg atatctggtt gccaagtcca tttggcatcg aatttttcaa gtaggtcaaa
    21481 gctggcttga ggtcccatgc ttccagcttt atagtcatga agtggggcac cattttcggc
    21541 ccagagctct tcaatacggt caatcaactt ccatgacgca ccaacctcat cccagtggct
    21601 aaagttagtt gagttgttat ttaggacatc ataaatcaat ttctcgtatg gttctggaga
    21661 agcaccagtt gcagtcgcgt ctgtacgata atcaagtgag ttaggagcca agttaaattc
    21721 ttctcctact tgcttcccat ttaggctaag agagaagcct tctgttggtt gaatatagat
    21781 ggtcaaaata tttggagcaa gtggttctcc aaagatagaa tccatttgtt taaagacgat
    21841 gttgacatga gttccttttt cagtcagtcg tttacctgta cggaaaaaga aaggaacacc
    21901 acgaaatcga tcgctgtcta caaagaaggc accagatgta aaggtttcag ttgttgattc
    21961 tggattcaca tttggttcgc tacgataaga gatgtatttc atgccatcaa tcttaccaga
    22021 gcggtattgt ccacggataa agtgttcttt gagttcttca tcagttggat gatagaggtt
    22081 tttaaagacc ttaatctttt cagcacgaat ctcgtctttt gtgaagcttg ctggtttgtc
    22141 catggcgagg agcgaaagaa gttgtagagt gtggttttgg accatgtcac ggagggcacc
    22201 ggattggtca tagtagccac cacgttcttc tacacccaag cgctccgcaa aggtaatttg
    22261 aacattgtcg ataaaatcct tgttccaaac gttttcaaaa atcaagtttg caaagcgaac
    22321 tgcaaagatg ctttggatca tttccttacc aagataatgg tcaatacgga aaatttgttc
    22381 ttcgtcaaat gttgctagga gttcgtcatt caacttgctt gcagttgcgt aatctgtacc
    22441 aaatggtttt tcaacgatca agcgctcaaa acctttgcca tcgacaatgt tttcagattt
    22501 gaggtgtttg gcaatggttc caaagaactg aggtgccata gacaagaaga agagcttatt
    22561 gtgttcagct tggtattttt cattaagctc agcttgtaat tgacgcaaag caatataatg
    22621 ttccgaatca ttgacatcat ggctttgata gtagaagtgg ctagcaaatt cttgggcttg
    22681 ctcggtacta tctgccaaat caaggatgga ctcgacaact acagattcaa aatattcctt
    22741 actccaaggt ctacgggcag ttccaataac ggcaaagtgc ttggaaagat tgccggattg
    22801 atatagtcta aaaagggaag ggtagagctt gcgtttagcc aggtctccac tcgcaccgaa
    22861 aattgtaaca ataaccttag atgacatcta gctacctaat ttctattttt attcctagtc
    22921 ttgctaggta tgaggaaacc tcatttcata aacttaattc taacataatt ttccgaaaaa
    22981 tcaaaaattc caatacgagg tagaaaaact gcaaggaaat ccttacagtt tgagtttaga
    23041 cgtttaagac cttatctaag aactctttca gacgagggtg ttgtgggtta tcaaagattt
    23101 ggtcaggtgt tccgtcttca aggaactcgc catctgcagt aaagataacg cggttggcaa
    23161 cctgacgagc aaatcccatc tcatgggtta cgataatcat ggtcatgcct tgctcagcca
    23221 attccttcat aacgttaagt acgtctccaa ccatctcagg gtcaagggca gaagttggtt
    23281 catcgaagag catgatgtct ggattcattg ctaggccacg agcgatggcc acacgttgtt
    23341 tttgaccacc tgataggcta tctggattgg cattagcttt atctgctagt ccaacctttt
    23401 caagcaactc cattcccaat tcctcagctt cttccttagt catcaacttg tgctcaatag
    23461 gagcaaaggt gatgttgtcc aatacagaca tatgagggaa gaggttgaag tgttggaata
    23521 ccatgccgat attttcacgg acgtggtcaa cattggttgt tttttcagtt aaatcatagc
    23581 cgttcacagt gatgtgaccg ctagtgactt cttctaaaag attgaggcta cggaggaaag
    23641 ttgacttacc agaacctgaa ggaccgatga tacaaacaac atctccttca tagaacttag
    23701 tcgtaattcc ttttaggact tcattttttc catagtactt gtgtaaatca tttacatcaa
    23761 tttttaattt tgccattaac gaatcctctt ttctaagcgt ttcgctagtc tagtcaaaag
    23821 tgtgataatt acaagataga agatagcaag gattgcatac atcttgaaac tttggtagtt
    23881 acgagcaatg ataatcttac cagtttggaa gagttcaacc aaaccgatag cagatacgat
    23941 agttgtatct ttaagagcga taacgaattg gttgacaaag tttggcaaca tcaatttagt
    24001 tgattgtggc aagataatct tacgcatggt ttttccataa gagataccca agcttcggct
    24061 ggcttccatt tggccaactg gaacggcctg aataccacca cgaacgattt cagcgatata
    24121 agcagccgca ttgagtgaga gggcaattgt tccagctaca aagtcgttaa ttgggctttg
    24181 ttggcctgtg atagactcga tgaagtttgg aattccccag aagatgaagg ctgcaagaat
    24241 catcaatgga ataccacgaa taacgtcaac gaaaatctca gagatgacgc gaagagattt
    24301 gtatgggcta acgctaaaca taccgaagat aattccgatg acaatggcaa tagcaaatga
    24361 gataagagct agagcaagag tgataccaag accgctaagg agttgtttgt agttgttttg
    24421 aagcaagccc cagagcgttg tttcgtcaac agtacttgtt gaagcagttg aagattcgct
    24481 agctaggtat ttgtcaagaa tcttttggaa ttcaccgttt gctttaaggt ttgcaagtcc
    24541 gttgttgaac atttcaatca gttctggatt tgctcctttt ttaacggcaa aggctgtttc
    24601 accgattgga gttccagaga ttggagtttt caatttttga ccttggctga tagaatattt
    24661 gagaacaggt tcatcatcca taacggcatc aatggcacca gtgtttaaac tgtcatacat
    24721 tgaagaacca tcagcaaagg ttttgatttt gtaaccgtat ttgctttgat tttctgttag
    24781 gaaggtttga gaagcagttc cgtttttaac accgactgtc tttcctttta gatcttcata
    24841 agaagcaata ttgcttgatt ctttgacacc aagaatggta ttagcagtgt agtatgattc
    24901 tgagaagtca aaagttgcct tacgagcatc tgtgacagac ataccagcaa tgataccatc
    24961 ggcttgacca gcttggacag cactgatagc agcatcaaaa ccagggttgg tgatttcaat
    25021 ttcaaaacct tggtctttag cgattgcctt aatcaattcc atatcaatac cagtgtattg
    25081 gttgcttgaa ttttggaaaa caaaaggtgc aaaagaagaa tcgctggcaa tgatatattt
    25141 agccttaaca ggaatagctt ttaatcctgc gagagtagtt gtagttggca ctgctgaaga
    25201 tgatgaagca gtccatttct tgataatttt atcaagacta ccatcttttt tcatttcagc
    25261 caaggcttgg ttaaattcag taaccaggtg ctcgtattta cttccttttt tcacaccgaa
    25321 agcaaaactt cctacagctt caccatccat ttcaatatgg aggtcttgac cttggttaat
    25381 ggcatattcg ataacaggtt tgtcatccat catggcatcg atggcaccag cactcaagct
    25441 gttgttcatt aaatcaccag tgtcaaatgt tttaatagta aagccgtatt tatctttgat
    25501 tgtttcaagg aaacgttgag cggcagttcc gtttttaaca ccaacggttt tgccagttaa
    25561 ttggtcgtac ttgctaattt tgtgtgactt tgtagtagca atgacaactt ttgtatcata
    25621 gtaagtatca gacatggtga agactttttc acgttcttta gtctttgtca tccctgccat
    25681 gatagcgtcg gcttgcccag cttgaaccgc attgactgct gcgtcaaatc caggatagga
    25741 catctgaatg ttccagcctt taatctcagc gactttgtta ataatgtcaa catcaattcc
    25801 tttataagtt tgatctgaat ctttaaactc aaaaggtgca taggcggtat cagaaacaat
    25861 cttaatcgtt tctgctttgg caatacctaa tgagaaaatt gggaataaaa ttagcaaaaa
    25921 tgctagaaat tttttcttca tttttagtct ccttttccga atattctctc attatatcag
    25981 aaaaagtaaa aaaaggcaaa tttttatatt tttcgtgtca gaaaatataa cattgatttt
    26041 tccttttctt tcttgaattg ctattaaaaa gtgatataat aatagtatat atagaagaaa
    26101 agaggacggg gatatgaaga acaaaagaat atttaaagac ttccaagctt caaaaatgaa
    26161 tttaaacatt tacacaagcc ccttgttagc ctttgttttt gtcttcatag gagagtttgt
    26221 ggcttatact ttatatggta ttagtttgtt agctctcatc ggacttgcta gaaattttgg
    26281 agaggctggt caaaatcttg caagctactt gcagaccttg catcagagct tgacggataa
    26341 aacaagtgac tttcgtttaa ttttaggatt actggccttt ggttttattc ttaacactgt
    26401 gttcagatgg acaagaaaag ttgagaaaag acctattcga accttgggat tttatagaga
    26461 gaatttcctc agcaatcttc tgaaaggatt tagtctaggt ctggcacttt ttcttctgac
    26521 cttgttaggt ttggtggtct taggtcaata tcgtttggaa tccattcact tgaatcctta
    26581 ttctcttgcc tttgtcgtct ttactatccc attttggatt ttacagggga cagcagaaga
    26641 agtggtggcc cgtgcttggc tacttcctca attggcctca agaaccaatc taaaactagc
    26701 tattcttata tctagcctgt tctttaccct gcttcatatg ggcaattctg gtctcacccc
    26761 tctatctcta gtaaatctct ttttattcgg agttgccatg gctctttacc ttctcaaaac
    26821 tgatacagtt tggggtgttg caggtattca tggtgcttgg aattttgctc agggtaatct
    26881 ctttgggatt ttagttagtg gtcaaccgtc aggaacgtct ctgatgacct ttttaccaca
    26941 aggcaatcaa gattggctat caggtggttc ttttggcata gaaggttcca ttatgacaag
    27001 tctggtatta ctactgctga ttgtctatct tgctaataaa ttaaagaaag aaaatgaaag
    27061 gatgtgactt cggtccgtcc ttttcttcgt gaaaatacta taagtatgct aaaataggaa
    27121 tagcacatgg agagaggatt cttatgatca atcacattac agataatcaa tttaaactag
    27181 tatcaaaata tcaaccatca ggagatcaac cccaagctat cgagcagttg gtggataaca
    27241 ttgagggggg agaaaaagct cagattctga tgggggcgac tggaacaggg aagacctata
    27301 ctatgagtca ggtcatttct aaagtcaata aaccaactct ggttattgcc cacaataaaa
    27361 ctctggctgg tcagctctat ggggagttta aggaattttt ccctgaaaat gcagttgagt
    27421 atttcgtatc ctactatgat tattaccagc cagaggccta tgtcccttct agcgatacct
    27481 atattgagaa ggatagttct gtcaatgacg agattgacaa gcttcgccac tcagctacct
    27541 cagccctttt ggagcgtaat gatgttattg tcgtggcctc agtctcttgt atctatggtt
    27601 tgggttcgcc caaggaatac gctgatagtg tcgttagtct ccgtcctggt ctagagattt
    27661 ctcgtgataa actcttgaat gacttggtcg atattcagtt tgaacgtaat gatattgatt
    27721 tccaacgcgg aagatttcgc gttcgtgggg atgtggtaga gattttccca gcttcccgag
    27781 atgaacatgc ctttcgagta gaattttttg gagacgaaat tgaccgtatt cgtgaagttg
    27841 aggctctgac aggtcaggtg ttgggagaag tggatcattt agcgattttc ccagcgacac
    27901 actttgtgac caatgacgac cacatggaag ttgccattgc aaagattcag gccgagttgg
    27961 aagaacaatt agctgtcttt gaaaaggaag gtaaactgct tgaagcccag cgtttgaaac
    28021 agcggacaga gtatgatatc gaaatgttgc gtgagatggg ctataccaat ggggttgaga
    28081 actattcacg acacatggat ggacggagcg aaggagagcc tccttatacg ctcttagatt
    28141 tcttcccaga tgatttctta attatgattg acgagagtca catgaccatg gggcaaatca
    28201 agggcatgta caatggagac cgttcgcgta aagaaatgct ggttaattat ggcttccgat
    28261 tgccgtctgc tttggacaat cgtcctctcc gtcgggagga gtttgagagt cacgttcatc
    28321 agattgttta cgtttcagcg acacctggtg actatgaaaa tgaacagact gagacagtga
    28381 ttgagcaaat cattcgtcca acgggactct tggatcctga agtggaagtc cgtccgacta
    28441 tgggacagat tgatgacctc ttgggtgaaa tcaatgcccg cgttgaaaaa aatgagcgta
    28501 cctttatcac aactttgacc aagaaaatgg cagaggactt gaccgactac ttcaaggaaa
    28561 tgggtatcaa ggtcaagtac atgcactcgg atatcaagac cttggaacgg acggagatta
    28621 tccgtgacct gcgcttgggt gtctttgatg tcttggtcgg aattaacctg ctccgtgaag
    28681 gaattgacgt tcctgaagtg agcctcgtag ctattctcga tgctgataag gaaggtttcc
    28741 ttcgcaacga acgtggactc atccagacta ttggacgtgc tgctcgtaac agtgaaggcc
    28801 atgtcatcat gtatgcagac acggttaccc agtctatgca acgtgctatc gatgaaactg
    28861 cccgccgtcg gaaaattcag atgacctata atgaagagca tgatatcgta ccacagacaa
    28921 tcaagaaaga aatccgtgac ctgattgccg tgaccaaggc agttgctaag gaagaggaca
    28981 aggaagtcga catcaatagc ctcaacaaac aagagcgcaa ggaactcgtc aagaaactag
    29041 aaaaacaaat gcaagaagcc gtcgaagtgc ttgactttga actggcggct cagattcgtg
    29101 atatgatgtt ggaagtcaag gtcttggatt aggggaatag tatgatttat ttaagaaagt
    29161 taaagagaga agatttgatg tctttatggg aaatggctta ttcacaactt aatccagttt
    29221 ggaaacagta tgatgctccc tattatgatg attatcagta tttttcaaat tttaaagaat
    29281 tcgaactaca aaaatcagaa tccattttaa gcaactcaaa tcgccttggt atttttgttg
    29341 atgataaact agttgggact gtttcgcgtt attgggtatg taaacaaaca agatggatgg
    29401 aattgggaat tggtatttat gataaaaaat tctggaacac tggtattggg aaagttgcta
    29461 tgttgcagtg gatagatagg acgtttcagg attacttgga gttggagcat ctgggtttga
    29521 caacttggtc agggaatctt ggtatgatga aacttgctga aaaattaaga atgaaaaaag
    29581 aagctcatat tccaaaagtt cgttattatc aaggtaaata ttttgatagt attaaatatg
    29641 gtattttgag agaagactgg gagaaaataa atgacggtta ttatcaaatc aatggaaact
    29701 cctgaagaga tagaaggtaa atcccttgtt cactggcaaa cgtggagaga ggcttatgat
    29761 gaccttttgc ctgcagaatt tcaggaaaca atgacattag aaagatgtcg attctttagt
    29821 caaaagtatc cagaaaatac attgattgcg atagatgacc tgaaggtagt tggttttatc
    29881 agttatggca gctttcgtga tgagactatt caagctggtg aaattattgc tttatatgtt
    29941 ttaaaagact attatggaaa aggaatcgca caaaagttag tgaaagtagc tttgactgct
    30001 cttaatcatt tttctgaaat tttcttatgg gtattgaaag ataataagcg cgccattgct
    30061 ttctatcaaa aaatgggttt tacttttgat ggacaagaaa agatacttga acttggaaag
    30121 cctataaagg aaaaacggat ggtattctat tctaaataat tttaaaaagt aaaagctaat
    30181 atctctggta ccaagtctga aaatttaata aattagaaag cgagtaaatt tatgtcccgt
    30241 tcacaattaa cgattttaac aaacatttgt ctgattgaag acctcgaaac tcagcgcgtg
    30301 gtgatgcagt atcgcgctcc tgaaaacaat cgctggtctg gttatgcctt tccaggaggc
    30361 catgtagaaa atggcgagtc tttcgcagag tctgtcattc gtgaaatcta tgaagaaaca
    30421 gggttgacta tccaaaatcc tcaacttgtc ggcattaaaa attggccact ggatacaggt
    30481 gggcgctata ttgtcatttg ttataaggca actgagttta ctggaactct tcaatcttca
    30541 gaagagggag aagtttcttg ggtgcaaaaa gaccagattc caaacttgga tctggcctat
    30601 gatatgctac ccttgatgga gatgatggaa gctcctgata agtctgaatt tttctaccct
    30661 cgccgtacag aagacgattg ggaaaagaaa atcttctagt cttttactaa ataacctagc
    30721 tgatccaagg cctcctcgat atagtggagg tcttgttgtg tttcggcttc gactaggtgg
    30781 taatggatgc catctgtcaa ttcagataga ggtctaaagt cagaatgctc gacttgttct
    30841 agaaaatgtt gcacatctct gcgacaagac agtttaagca aggtttcaat ttctccataa
    30901 acgggatggt caatcaaggt attctggaca tgcccaccat tatcgacaat agcaaggagt
    30961 tcctgaccga tttcttcaac ttcatgtttc actttgaaaa gtttgtgaac ataaggattg
    31021 gtatcaattt gcttatagat gtagccacga ttggtggata ggataggagc gccatcggct
    31081 ctcaaaattg caatgtcctg cacaatgacc tgacgtgtga catgaaaatg ttccgccaaa
    31141 ctttggccat taagggcttt aggagcttct ttcaagagtt ggagcagggc ttgtttgcga
    31201 tcttttgtca tagcttttcc ttttaacggc gttttcgaag cactttatag acagctagtg
    31261 ctaatgtata gtctaccata ctatggataa ttgtgccaaa tccaactagc acaaatagaa
    31321 catagaacat gttttctaca ttggtacccg aagttgcgta aaaaaggaca caggctaata
    31381 cttcagcaag ggcatgaaca acagccaaaa caaagttgaa aacccaggaa gattttggtt
    31441 tatctagggt atcggggaat ttttgtaggt aaagagctcc taaagcacca aaagatatat
    31501 gggaaaaagc ccgaaaaacg ataaccatgg gatagccagc catcaaaaat ccaaaactag
    31561 aggctaggat gacaaaaact gccatcaagg gcgacaagaa catggctata aaaatagcga
    31621 tgtggctccc caaagtatag gaagcaggtg gaatgacaat cttgaaaggc ataacaattg
    31681 gaatcaaaat cgcaatagcc gttaaaaggg ctgtcattgt cataaattgt gtctttttcc
    31741 gtgtattcac aagaatctcc tttttaactg catatacact agtatggtac aataaaccag
    31801 acaataaagc aagaatttac ttgggtttat agataatttt ttagttaaaa gttatagtag
    31861 attgaaacta gaatagtcca cctctacttc taaaacattg ttagaaatcg atttggctgt
    31921 cctgatcgat ttatcctgtt cttatttcgt tttactatag taaagatttc attaaaaaga
    31981 aactgtatag agcaaaatct ccaccttcag gtttgaaagc ggagattgtt tttatttttt
    32041 caaggtttgt agtcgtggaa caatggctag ggttagaatt gcagaaatga ccaattcagc
    32101 aattgaattt gttgagataa cggttgccag aagaagttgg atatttccat tataaacatt
    32161 tccaaatagg aagaagattc ctccaaggac aaagatagta tttgtcaagg aaccaagggc
    32221 tccagctaaa atcagaccag tcttgttttt catcagttta tagactaagt aaggagttaa
    32281 accaatcaaa atacgtggga cgatggcaat gatagctgag tagatgtttc cgtttggtac
    32341 gaagggagag aagaggtagc ttgtcggtag aatcgtaatc gtgttaaccg tcaagctaag
    32401 taatcccatc aaaaatccaa gtgtaacccc aactcgtgga ccataaataa tgctggcaat
    32461 aatgacagga atatgaacaa tggtcggttt gattggaaat ggaaaaaggt taaagataag
    32521 tgagctcaga aagtgtatca cgagcatggt agcaaaaaag atagcaatgg gtgcaatatt
    32581 agagcgtttt ttcatcgata gtttccttta ttctttctaa aataattgtg aggtcagcta
    32641 aagctcctcg tccgtggtct ccacaagcta gtagggattc cttaggagca atcagctgat
    32701 agccgtaggt ttctaatgtt ttcagattat tctgagttac tggatggtca tacatttttg
    32761 tattcatagc aggagctatt agtttgggaa tatgacttgg tagggctaga gctgtactgg
    32821 ttaccatgtt gtccgcaaat ccgtgagcta gttttgcaat agtgttagca gttgcaggta
    32881 ccacgataaa taaatctgct ttttttccaa gttcgatatg attgacctga tcaggatagg
    32941 gttccttcat gacatccaag tggacaggat tctgtgagag tacctgtagt gtcaaaggtt
    33001 ggataaactc tgtagcagcc tgagtcatta agacagtgac ttgatggcct tgttttttta
    33061 gagaactgac taaatctgcc gacttataag aggcgattga acccgttaca gccaagagaa
    33121 tgtttgccat agttttcctt tctaagaatg ataggcttga attttttcaa ggaggagttc
    33181 tgcaatttct tctttagtct ggactgtttg aagctgattt ttctcaacaa atatagctcg
    33241 gtgctgatct gctgaaattt gagtcaggtc attcgcgatg attaaatctg cttgattctt
    33301 gataagactt tttcgtgcaa tgtcaaccag atgatcttcg gtaacatcaa ccagcagttt
    33361 gaaaccaatc agatgaatag taggattcca ttccttgact agggatatga ttttgggtgt
    33421 ctttttaagg aacaaaacct gaacctcatc agttgaagaa atcttggcct gatgattctg
    33481 cttgcttaaa aattctttta gattggagct agcctgaact tcctcaagcc ctgtcatata
    33541 aacaggagtg tagtcagaaa cagccattga gtggatcaag acctgataat cctgaacacg
    33601 ttcttgcatt tctattagaa ggtccttggt attggtaatt tctcgaatac ttaggttagg
    33661 atgaggctct ggcttcagag ctcgttttgt cgtaattaaa caaacttcat gccctgcaga
    33721 aagcaaagtc tctgtgataa ttttccccaa gtgacctgta gaatggttag tgatagagcg
    33781 gacgctatcg atagcttcac tggtaccgcc cgatgtaact aaaattttca tagcactatt
    33841 gtacacaaaa ataagcggta agtaaaatga aagtgataaa tttttggtaa aaacgaagat
    33901 ttattatagt ttcaaactat aaagccatat aaaatttaag aaaggactct aaaagcctta
    33961 aaaacagaga tatttacgaa cgtttagaga gttttaggat gttaaaaatc ttgttttgtg
    34021 atataatgaa ttatcatata agaggttaga ggaattttga atgaaaacag atattgaaat
    34081 cgcacagagt attgagttga agccaattgt tgatgttgta gagaaacttg gtatttctta
    34141 cgacgatttg gagttgtacg gaaagtacaa ggctaaactc agctttgata aaattcgggc
    34201 agttgagagc aatccagtcg gtaaattgat cttggttact gccatcaacc caacacctgc
    34261 aggtgaagga aagtctacgc ttaccattgg tcttgcggat gccttgaaca agattggcaa
    34321 gaaaaccatg attgctatcc gcgaaccgtc tcttggtcca gtcatgggga tcaagggtgg
    34381 tgctgctggt ggtgggtatg cacaagttct gccaatggaa gacatcaacc tccactttac
    34441 tggagatatg catgctatta caactgccaa caatgccctt tctgccttga ttgacaacca
    34501 cttgcaccaa gggaatgagc tgggaattga tcaacgtcgt atcctctgga aacgcgttgt
    34561 ggacttgaac gaccgtgcgc tccgccatgt gactgttggt cttggtggtc ctctaaacgg
    34621 tattccacgt gaggatggtt ttgatattac agttgcttca gaaatcatgg caattctttg
    34681 cttggcaacg gacatcgagg acttgaaacg tcgtttggcg aatatcgtta ttggttatcg
    34741 ctatgaccgt acgcctgttt ctgtaggtga tttgcaggtt gagggtgcct tggctttgat
    34801 tttgaaggat gctattaagc caaacttggt tcagacaatt tacggtacac ctgcctttgt
    34861 acacggtggt ccatttgcca atatcgctca tggctgtaac tctgttttgg cgacgacaac
    34921 agcccttcac ttggctgatt acactgttac tgaagctggt tttggtgcgg accttggtgc
    34981 tgagaaattc cttgatatca agacaccaaa cttgccaaca tctccagatg cagttgttat
    35041 tgtcgcaacc cttcgtgccc ttaagatgaa tggtggtgtg gctaaagatg ctctgactga
    35101 agaaaatgta gaggcagttc gtgcaggttt tgctaacttg aaacgccacg ttgaaaatat
    35161 ccgtaagttc ggtattccag cagttgtagc tattaacgaa tttgtatctg atacagaagc
    35221 tgaaattgca gccttaaaag aactctgtgc cttaatcgat gtaccagttg aattggctag
    35281 tgtctgggct gatggagtag aaggtggagt agaacttgcc gaaacagttg ttaagacaat
    35341 tgctgaaaat ccagctaact ataaacgttt gtatgataat gacctttctg tccaagaaaa
    35401 gattgaaaaa attgtcactg aaatctatcg tggtagcaaa gtgaactttg agaagaaagc
    35461 tcaaacacaa attgctcaag tcgttcaaaa cggttgggac aaattgccaa tctgtatggc
    35521 taaaactcaa tacagtttct cagacaatcc aaatgcgctt ggagcaccag aaaactttga
    35581 aattaccatt cgtgaattgg taccaaaatt aggtgcaggc ttcatcgttg ccttaactgg
    35641 tgatgttatg accatgccag gtcttccaaa acgtccagca gctctcaaca tggatgttga
    35701 aagcgatgga actgtactag gcttgttcta gtggattgaa attgacttta agtgagtttg
    35761 gaaataatat ccaagctcat tttttctcag actgcaagca gttcatcaat aagatttata
    35821 ctcttcgaaa atctcttcaa actacgtcag cttcaccttg ccgtaggtat atgatactga
    35881 ctctgtcagt tctatccaca acctcaaaac agtgttttga gcaacctgcg gctagcttcc
    35941 tagtttgctc tttgattttc attgagtata agtagataga aaagttatat actatctatt
    36001 gaaaatatta taaatcagat acaaagacag gtgaaacctt ctgtgttata ctagagatat
    36061 gttagatttg aaagaatacg gtatcgtcat gtggccggag gagaaagtca tttctttccg
    36121 tgagaaactt ctcgcttggt atgatgaaaa caaaagagat ttgccttgga ggagaagtaa
    36181 aaatccttat cacatctggg tatctgaaat catgcttcag cagaccaggg tggatacagt
    36241 tatcccttac tacgaaagat tcctggactg gtttccaact gtcgaaagtc tggcaactgc
    36301 gtctgaggag agtttactga aagcttggga gggcttgggc tattattctc gagttcgcaa
    36361 tatgcaggct gcagcccagc agattatgac tgactttggt ggccaatttc caaataccta
    36421 tgaaggaatt tccagcttga aagggattgg accttacaca gcaggagcca tttccagtat
    36481 tgcttttaac ttgcctgagc cagctgtaga tggtaatgtc atgcgggtct tggcgcgtct
    36541 gtttgaagtc aaccacgata ttgggattcc aagtaatcga aaaatttttc aggcaatgat
    36601 ggagatcttg attaatccgg atcgtccagg tgattttaat caagccttga tggacttagg
    36661 gtctgatatt gagtctcctg taaatcccag acctgaagaa agcccagtca aggactttag
    36721 tgcggcatat cagaatggaa ccatggaccg ttatccaatt aaatctccta agaaaaagcc
    36781 ggttcctatt tatcttaaag ccttagttgt gaaaaattct caaggacaat ttttacttga
    36841 aaaaaatgaa agcgaaaagc tcttggcagg tttttggcat ttccccttta tagaagttga
    36901 taacttttcg caagaagagc agtttgacct ctttcatcag gttgcggaag aaagtgtgaa
    36961 ctttggtccc agtccagaag agagtttcca gcaggactat gacctagatg ttgattggct
    37021 tgatgtttgt tttgatacag tccagcatgt ttttagtcat cgaaaatggc atgtgcagat
    37081 tgtagcaggt caggtgagtg acttccatga tttttcagat agggaagttc gctggctttc
    37141 accagaagaa ttcaagaatt acccacttgc caaaccccaa caaaaaatct ggcaggctta
    37201 tgcacaagcc aacttagaca gtagccaaga ctagctattg tgtcttctga ctattttttt
    37261 ggtataatag tggagaaaaa ggtgaacata tgaaaaaaat actaattgta gatgatgaga
    37321 aaccaatctc ggatattatc aagtttaata tgaccaagga aggttacgaa gttgtaactg
    37381 cttttaatgg tcgtgaagcg ctagagcaat ttgaagcaga gcaaccagat attattattc
    37441 tggatttgat gcttccagaa attgatggtt tagaagttgc taagaccatt cgtaagacaa
    37501 gcagtgtgcc cattcttatg ctttcagcca aagatagtga atttgataag gttatcggtt
    37561 tggaacttgg ggcagatgac tatgtaacga aacccttctc caatcgtgag ttgcaggcgc
    37621 gtgttaaagc tcttctgcgt cgttctcaac ctatgccagt agatggtcag gaagcagata
    37681 gtaaacctca acctatccaa attggggatt tagaaattgt tccagacgcc tacgtggcta
    37741 aaaaatatgg cgaagaacta gacttaaccc atcgtgaatt tgagcttttg tatcatttag
    37801 catcgcatac aggtcaagtc atcacgcgcg aacacttgct tgagactgtc tggggttatg
    37861 actattttgg tgatgtccgt acagttgatg tgactgtacg acgtctgcgt gagaagattg
    37921 aagatacgcc cagccgacca gagtatatct tgacgcgccg tggtgtaggg tattacatga
    37981 gaaataatgc ttgatttact gaaacaaacc atttttacca gagattttat ctttatcctg
    38041 attttgttag gtttcatcct tgttgtgacc ctcttattac tggaaaatag acgtgataat
    38101 attcagttga agcaaatcaa tcaaaaggtt aaagatttga ttgcaggaga ttattccaag
    38161 gttcttgata tgcaaggtgg gtctgaaatc accaatatta ccaataattt gaatgacttg
    38221 tcggaggtta ttcgtctcac tcaggaaaat ctagaacaag agagtaagag gctaaatagt
    38281 attctgtttt atatgacaga tggggttctt gcgaccaacc gtcggggtca gattatcatg
    38341 attaatgata cagccaagaa gcaactgggg ttggttaagg aagatgttct gaatagaagc
    38401 attttggaat tgctcaagat agaagaaaac tatgaattgc gtgatttgat tacccaaagt
    38461 ccagaattgt tgctagattc ccaagatatc aatggcgaat atttgaacct tcgagttcgc
    38521 tttgccttga tacgtcgaga gtctggcttt atttcaggtt tggtggctgt tttgcatgat
    38581 acgacggagc aggagaagga agaacgagaa cgaagactct ttgtttccaa tgttagccat
    38641 gagttacgga ctcctctgac tagcgtaaaa tcctatcttg aagccttgga tgagggggct
    38701 ttgtgtgaaa ctgtagcacc agactttatc aaggtttctc ttgatgagac caaccgtatg
    38761 atgcgcatgg tgacggatct cctccatctt tcacgtattg ataatgctac cagtctccta
    38821 gatgtggaac tgattaactt cactgctttt attaccttta tcctcaatcg ttttgacaag
    38881 atgaaaggac aggaaaagga gaaaaaatat gagttggtga gagattatcc catcaattct
    38941 atctggatgg aaattgatac agataagatg acgcaggttg tcgacaatat tttaaataat
    39001 gctattaagt attcgccaga tgggggtaaa atcactgtca gaatgaagac aactgaagac
    39061 cagatgattt tatccatttc tgaccacggt ttggggattc ctaagcagga tttaccacgt
    39121 atctttgacc gtttctatcg tgtggatcgt gctagaagtc gtgcacaagg tggtacaggt
    39181 ctaggactgt ctatcgctaa agaaattatc aaacaacata agggctttat ttgggccaag
    39241 agtgaatacg gcaagggttc aacctttacc attgtgctcc cttatgataa ggatgcagtg
    39301 aaagaagaag tatgggagga tgaagtagaa gactagaatg agtgaaatag gctttaaata
    39361 cagtatttta gcgtcgggtt ccagtggaaa ttctttttat ctggaaacct caaaaaagaa
    39421 gcttttagtg gatgcaggct tgtctggcaa gaaaattacc agtctgctag ctgaaattaa
    39481 ccgcaagcca gaagacctgg atgccatctt gattacccat gagcattcag atcatatcca
    39541 tggagtaggc gttttggctc gcaagtatgg tatggatctt tatgccaatg aaaagacctg
    39601 gcaagctatg gaaaatagta aatatcttgg caaggtggat tcttcgcaaa agcatatttt
    39661 tgaaatgggt aaaaccaaaa cttttggaga tatcgacatc gagagttttg gtgtaagcca
    39721 tgatgcagtc gcaccgcagt tctatcgctt tatgaaggat gacaagagtt ttgtcctttt
    39781 gacagataca ggttatgtca gtgaccgtat ggcgggcatt gtcgaaaatg cggatggcta
    39841 tcttatcgag gccaaccatg atgtagagat tttgcgatca ggttcttacg cttggcgact
    39901 caaacaacga atcctatctg accttggtca cctttctaac gaggacggtg ctgaagctat
    39961 gattcggacg ctaggaaatc gtactaagaa gatttacctt gggcatttat ctaaggaaaa
    40021 caatatcaag gaactggctc atatgaccat ggtcaatcag ctggctcaag ctgatctggg
    40081 agtcggagta gactttaagg tttatgatac ctcaccagat accgcaacac cattgacaga
    40141 gatatagaaa gaacgctgag aaggtgtt
//
LOCUS       DBEROT010000017        37439 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.17, whole genome shotgun sequence.
ACCESSION   DBEROT010000017 DBEROT010000000
VERSION     DBEROT010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 37439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.17"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..225
                     /locus_tag="ACL8CG_001020"
     CDS             <1..225
                     /locus_tag="ACL8CG_001020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343629.1"
                     /translation="GFTHYKYYRAFLISFGIPINIEITYLSIDGLVLVVTFQFINQKC
                     DGFIVYETASKIKKNLSSQFFYARLVKIKF"
     gene            239..808
                     /locus_tag="ACL8CG_001021"
     CDS             239..808
                     /locus_tag="ACL8CG_001021"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343630.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGKFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMYQHEKGRIVTRVHYVLTKEDYFANK"
     gene            876..1526
                     /locus_tag="ACL8CG_001022"
     CDS             876..1526
                     /locus_tag="ACL8CG_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS1343631.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVHK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            1510..3750
                     /locus_tag="ACL8CG_001023"
     CDS             1510..3750
                     /locus_tag="ACL8CG_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGS1343632.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GYLNTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESDR"
     gene            3929..4117
                     /locus_tag="ACL8CG_001024"
     CDS             3929..4117
                     /locus_tag="ACL8CG_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343633.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHGHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            4150..4737
                     /locus_tag="ACL8CG_001025"
     CDS             4150..4737
                     /locus_tag="ACL8CG_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1343634.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            4741..5925
                     /locus_tag="ACL8CG_001026"
     CDS             4741..5925
                     /locus_tag="ACL8CG_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1343635.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIIFLLVGILFIESWGSSRKKEVFN
                     RS"
     misc_feature    6086..6217
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            6233..6763
                     /gene="infC"
                     /locus_tag="ACL8CG_001027"
     CDS             6233..6763
                     /gene="infC"
                     /locus_tag="ACL8CG_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGS1343636.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            6796..6996
                     /gene="rpmI"
                     /locus_tag="ACL8CG_001028"
     CDS             6796..6996
                     /gene="rpmI"
                     /locus_tag="ACL8CG_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGS1343637.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            7048..7407
                     /gene="rplT"
                     /locus_tag="ACL8CG_001029"
     CDS             7048..7407
                     /gene="rplT"
                     /locus_tag="ACL8CG_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGS1343638.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            7465..7845
                     /locus_tag="ACL8CG_001030"
     CDS             7465..7845
                     /locus_tag="ACL8CG_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1343639.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            8095..8895
                     /locus_tag="ACL8CG_001031"
     CDS             8095..8895
                     /locus_tag="ACL8CG_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGS1343640.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            8858..9844
                     /locus_tag="ACL8CG_001032"
     CDS             8858..9844
                     /locus_tag="ACL8CG_001032"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGS1343641.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            9886..12051
                     /gene="lytB"
                     /locus_tag="ACL8CG_001033"
     CDS             9886..12051
                     /gene="lytB"
                     /locus_tag="ACL8CG_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGS1343642.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(12112..13767)
                     /gene="pavA"
                     /locus_tag="ACL8CG_001034"
     CDS             complement(12112..13767)
                     /gene="pavA"
                     /locus_tag="ACL8CG_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGS1343643.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            13872..14369
                     /gene="ybeY"
                     /locus_tag="ACL8CG_001035"
     CDS             13872..14369
                     /gene="ybeY"
                     /locus_tag="ACL8CG_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGS1343644.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGEL
                     FISSDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            14350..14745
                     /locus_tag="ACL8CG_001036"
     CDS             14350..14745
                     /locus_tag="ACL8CG_001036"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS1343645.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            14762..15661
                     /gene="era"
                     /locus_tag="ACL8CG_001037"
     CDS             14762..15661
                     /gene="era"
                     /locus_tag="ACL8CG_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGS1343646.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            15710..16534
                     /gene="mutM"
                     /locus_tag="ACL8CG_001038"
     CDS             15710..16534
                     /gene="mutM"
                     /locus_tag="ACL8CG_001038"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGS1343647.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLNQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            16534..17139
                     /gene="coaE"
                     /locus_tag="ACL8CG_001039"
     CDS             16534..17139
                     /gene="coaE"
                     /locus_tag="ACL8CG_001039"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGS1343648.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            17126..18325
                     /locus_tag="ACL8CG_001040"
     CDS             17126..18325
                     /locus_tag="ACL8CG_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGS1343649.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            18325..18474
                     /gene="rpmG"
                     /locus_tag="ACL8CG_001041"
     CDS             18325..18474
                     /gene="rpmG"
                     /locus_tag="ACL8CG_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1343650.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            18514..18747
                     /gene="secG"
                     /locus_tag="ACL8CG_001042"
     CDS             18514..18747
                     /gene="secG"
                     /locus_tag="ACL8CG_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGS1343651.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            18849..21203
                     /gene="rnr"
                     /locus_tag="ACL8CG_001043"
     CDS             18849..21203
                     /gene="rnr"
                     /locus_tag="ACL8CG_001043"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGS1343652.1"
                     /translation="MKDRIKEYLQDKGKMTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVLSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            21166..21633
                     /gene="smpB"
                     /locus_tag="ACL8CG_001044"
     CDS             21166..21633
                     /gene="smpB"
                     /locus_tag="ACL8CG_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGS1343653.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            21649..22509
                     /gene="tehB"
                     /locus_tag="ACL8CG_001045"
     CDS             21649..22509
                     /gene="tehB"
                     /locus_tag="ACL8CG_001045"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGS1343654.1"
                     /translation="MEKSVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            22582..23535
                     /gene="coiA"
                     /locus_tag="ACL8CG_001046"
     CDS             22582..23535
                     /gene="coiA"
                     /locus_tag="ACL8CG_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGS1343655.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHIANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            23554..25356
                     /gene="pepF"
                     /locus_tag="ACL8CG_001047"
     CDS             23554..25356
                     /gene="pepF"
                     /locus_tag="ACL8CG_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS1343656.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENRGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTIFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            25358..26071
                     /locus_tag="ACL8CG_001048"
     CDS             25358..26071
                     /locus_tag="ACL8CG_001048"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGS1343657.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFIMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            26138..27079
                     /gene="prsA"
                     /locus_tag="ACL8CG_001049"
     CDS             26138..27079
                     /gene="prsA"
                     /locus_tag="ACL8CG_001049"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGS1343658.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(27198..27539)
                     /locus_tag="ACL8CG_001050"
                     /pseudo
     CDS             complement(27198..27539)
                     /locus_tag="ACL8CG_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            27951..28046
                     /locus_tag="ACL8CG_001051"
                     /pseudo
     CDS             27951..28046
                     /locus_tag="ACL8CG_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(28299..28919)
                     /locus_tag="ACL8CG_001052"
     CDS             complement(28299..28919)
                     /locus_tag="ACL8CG_001052"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1343659.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(28919..29401)
                     /locus_tag="ACL8CG_001053"
     CDS             complement(28919..29401)
                     /locus_tag="ACL8CG_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGS1343660.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(29401..30243)
                     /locus_tag="ACL8CG_001054"
     CDS             complement(29401..30243)
                     /locus_tag="ACL8CG_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGS1343661.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(30338..31126)
                     /locus_tag="ACL8CG_001055"
     CDS             complement(30338..31126)
                     /locus_tag="ACL8CG_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGS1343662.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQHPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKAYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            31280..32659
                     /gene="glmU"
                     /locus_tag="ACL8CG_001056"
     CDS             31280..32659
                     /gene="glmU"
                     /locus_tag="ACL8CG_001056"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGS1343663.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            32669..33214
                     /locus_tag="ACL8CG_001057"
     CDS             32669..33214
                     /locus_tag="ACL8CG_001057"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1343664.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDENETLEVLEVSLEEAKELIQ
                     SGRICDAKTIMAVQYWELQKK"
     gene            33226..33540
                     /gene="macP"
                     /locus_tag="ACL8CG_001058"
     CDS             33226..33540
                     /gene="macP"
                     /locus_tag="ACL8CG_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGS1343665.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            33557..34249
                     /locus_tag="ACL8CG_001059"
     CDS             33557..34249
                     /locus_tag="ACL8CG_001059"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGS1343666.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            34326..34817
                     /gene="rocS"
                     /locus_tag="ACL8CG_001060"
     CDS             34326..34817
                     /gene="rocS"
                     /locus_tag="ACL8CG_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGS1343667.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            34915..35505
                     /locus_tag="ACL8CG_001061"
     CDS             34915..35505
                     /locus_tag="ACL8CG_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGS1343668.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQASAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            35514..37277
                     /locus_tag="ACL8CG_001062"
     CDS             35514..37277
                     /locus_tag="ACL8CG_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGS1343669.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT        11427 a         6752 c         8248 g        11012 t
ORIGIN      
        1 ggatttaccc actacaaata ttatagagcc tttttaattt cttttgggat tccgattaac
       61 attgagataa cctacctttc aattgacggt cttgttttgg ttgtcacatt ccagttcata
      121 aatcaaaaat gtgacggttt cattgtatat gaaaccgctt caaaaatcaa gaaaaacttg
      181 tcatcccaat ttttttatgc tagactagtg aaaatcaagt tctaatggag ggaaaagtat
      241 ggaatcaatt tttgtaaaac ttgcccagta tccgtctata gaaacggagc gtttattgct
      301 tagacctgta actttggatg atgcggaagc aatgtttgac tatgcctcgg acaagggtaa
      361 tacacgttac acttttccaa ccaatcaaag cttggaagaa accaagaata acattgctca
      421 gttctacttg gctaatccct tgggacgttg gggaatagaa ctaaaaagca atggcaaatt
      481 tatcggaaca attgatttgc acaagattga tcctgttctt aagaaggtag ctattggtta
      541 tattatcaac caaacgtatt ggaatcaagg attaacgaca gaaaccaatc gtgctgtgat
      601 tgagctagct tttgagaaga taggaatgaa taagttagtt gctttatacg ataaggctaa
      661 tcccgcatca ggaaaggtca tggagaaatc aggaatgcgt ttttcccatg cagaaccata
      721 tgcttgtatg taccagcatg aaaaaggccg aatcgtgaca agagttcatt atgtcttgac
      781 caaggaagac tattttgcaa ataaataagc agttgaaaag aaatttttcg actgtttttt
      841 cttcctctta cgaataatct aagagaggag aaaatatgga agcaattatc gagaaaatca
      901 aagagtataa aatcatcgtc atctgtactg gtctgggctt gcttgtagga ggatttttcc
      961 tgctaaaacc agctccacaa acacctgtca aagagacgaa tttgcaggct gaagtcgcag
     1021 ctgtttccaa ggatttggta tccgaaaagg aagtgaacaa ggaagaaaag gaagaacccc
     1081 ttgaacaaga tctaatcaca gtagatgtca aaggtgctgt caaatcgcca gggatttatg
     1141 acttgcctgt aggtagtcga gtcaatgatg ctgttcataa ggctggtggc ttgacagagc
     1201 aagcagacag caagtcgctc aatctagctc agaaagttag tgatgaggct ctggtttacg
     1261 ttcctactaa gggagaagaa tcagttagcc aacagactgg tttggggaca gcttcttcaa
     1321 taagcaagga aaagaaggtc aatctcaaca aggccagtct ggaagaactc aagcaggtca
     1381 agggactggg aggaaaacga gctcaggaca ttatcgacca tcgtgaggca aatggcaagt
     1441 tcaagtcagt agacgagctc aagaaggtct ctggcattgg tggcaaaaca atagaaaagc
     1501 ttaaagacta tgttacagtg gattaagaat ttctctattc ccctaattta cctgagtttt
     1561 ctattacttt ggctttatta cgctattttc tcagcatctt atcttgcttt gttgggcttt
     1621 gtttttctgc tagtctgtct ctttatccaa tttccgtgga aatctgctgg taaagttcta
     1681 ataatttgcg gaatctttgg attttggttt gtttttcaaa attggcaaca gagtcaagtg
     1741 agtcaaaatt tggtggattc tgttgaaagg gtacggattt taccagacac tattaaggtt
     1801 aacggtgata gtctatcctt tcgtggcaag tctaacggtc gtgctttcca agtctattat
     1861 aaactccagt ccgaggagga gaaagaagcc tttcaagctt taaccgacct gcatgagata
     1921 ggactagaag ggaagctttc ggagccagaa gggcagagaa attttggtgg ctttaattac
     1981 caagcctatc tgaagactca gggaatttac cagactctca atatcaaaaa aatccagtca
     2041 cttcaaaaga ttggcagttg ggatatagga gaaaacttgt ccagtttacg tcgaaaggct
     2101 gtggtttgga ttaagacgca ctttccagac cctatgcgca attacatgac aggactcttg
     2161 ctgggatatc tgaacaccga ctttgaggag atgaatgagc tttattccag tctaggaatt
     2221 atccacctct ttgccctatc tggcatgcag gtaggttttt tcatgaatgg atttaagaaa
     2281 cttctcttgc gattgggctt gacccaagaa aagttgaaat ggctgactta tcccttttcc
     2341 cttatctatg cgggactaac tggattttca gcatcggtta ttcgcagtct cttgcaaaag
     2401 ctactggctc aacatggggt taagggcttg gataattttg ccttgacggt gcttgtcctc
     2461 tttattgtca tgccaaactt tttcttgaca gcaggaggag tcttgtcctg cgcttatgct
     2521 tttatcctga ccatgaccag caaagaaggg gaggggctca aggctgttgc tagtgaaagt
     2581 ctagtcatct ccttgggcat attgcccatt ctatccttct attttgcgga atttcaacct
     2641 tggtctatcc ttttgacctt tgtcttttcc tttctatttg acttgacctt cttaccgctc
     2701 ttgtctattt tatttgtcct ttcctttctc tatccagtca ttcagctgaa ctttatcttt
     2761 gaatggttag agggcattat tcgcttggtc tcgcaggtgg caaggagacc gcttgtcttt
     2821 ggtcaaccca acgcatggct tttaatctta ttgttaattt ccttggcttt ggtctatgat
     2881 ttgaggaaaa acattaaagg attaacagta ttgagtttat tgattacagg tctctttttc
     2941 cttaccaagt atccactgga aaatgaaatc accatgctgg atgtggggca aggagaaagt
     3001 attttcctac gggatgtaac tgggaaaacc attctcatag atgtaggtgg taaggcagaa
     3061 tcttataaga aaatcgaaaa atggcaagaa aagatgacga ccagcaatgc acagagaagc
     3121 ttgataccct atcttaaaag tcgaggagta gctaagattg accagctgat tttgacaaat
     3181 acggacaagg aacatgtcgg agatttgtta gaggtgacca aggctttcca tgtaggggag
     3241 attttagtat caaaaggcag tttgaagcag aagcaatttg tggtagaact acaggcgact
     3301 caaacaaagg tgcgtagtat gacagtaggg gagaacttgc ccatttttgg aagtcagtta
     3361 gaagttctat ccccaaggaa aatgggagat ggaggacacg atgataccct agttctgtat
     3421 gggaaattct tggataagca atttctcttc acgggaaatt tggaggagaa aggagagaag
     3481 gacttgctga agcactatcc agacttgaaa gtaaatgttt tgaaagctag ccaacatggc
     3541 aataaaaaat catcaagtcc agcctttcta gaaaaactca aaccagagct tactcttatc
     3601 tcagttggaa agagcaatcg aatgaaactc ccccatcagg aaacattgac acgactggaa
     3661 ggtatcaata gcaaagttta ccgaactgac cagcaaggag ctatacgctt taaggggttg
     3721 gatagttgga aaatcgaaag tgatcgatag gaaagataaa tgttgtagat tagtgaaata
     3781 aactaaaaat ttgttgcata ataatgataa aaatggtata atgaaaacgt attcaatatt
     3841 gaggatataa aatcattaaa aattagcaaa aatcgtttaa ttagttagtt tataatctat
     3901 tggtcttctt cagtccagtg tatctgctgt gacagtcact aaaagttaca agtatgattg
     3961 gaatacggtt tgggaatata gtaccaacta tcacggccat cagtatgctt ggattccgtc
     4021 atggtctcgt tatgacagct attctgagta taaagttggc ggaggctgga actacggtcg
     4081 ttatgaggtc ataaactatt acagcggagg ctattaattc ttaaagagtg agaaaaagga
     4141 gggctagata tgttgcagct tactcatgtg accttaaaaa cgcgacaagt catcttgcaa
     4201 gatgcggatt ttacctttaa aaagggtagg atttatggcc ttcttgctat caatggctcg
     4261 ggaaagacga cactattccg agctatgagc aagttgcttc cccttagtag tggacacatc
     4321 gcagttcctc cttctttgtt ttattatgag agcgttgaat ggctggatgg aaacttaagt
     4381 gggatggact accttcgtct cataaaaaac atctggaagt cagacctaaa cttgagagat
     4441 gaaatcgcct actgggaaat ggctgactat atcagtcttc ccatccgcaa gtattcctta
     4501 ggcatgaagc aacgcttggt gattgctatg tattttctca gtcaggccaa atgctggctc
     4561 atggatgaga ttacaaatgg cttagacgag tattatcgac agaagttttt tgataggcta
     4621 gcacaaatcg atagacaaga acagctggtt cttttaagtt cccactataa ggaagagttg
     4681 gttgatatct gcgatagagt agtaaccatt catcaggggc agatagaaga ggtttagttt
     4741 atgaaagatg ttagtctatt tttattgaaa aaagttttca aaagtcgttt aaactggatt
     4801 atcttacttt tatttgcatc tgtactcggt gttacctttt atttaaatag tcagactgca
     4861 aactcacaca gcttggagag caggttggaa agtcgcattg cagccaacga gagggctatc
     4921 aatgaaaatg aagagaaact ctcccaaatg tctgatacca gctcggagga ataccagttt
     4981 gctaaaaata atttagacgt gcaaaaaaat cttttgacgc gaaagacaga aattctaact
     5041 ttactaaaag aagggcgctg gaaagaagcc tactatctgc agtggcaaga tgaagagaag
     5101 aattatgaat ttgtatcaaa tgacccgact gctagctctg gcttaaaaat gggggttgac
     5161 cgcgaacgga agatttacca agccctgtat cccttgaaca taaaagcaca tactttggag
     5221 tttccgaccc acgggattga tcagattgtc tggattttag aggttatcat cccaagcttg
     5281 tttgtggttg cgattatttt tatgctaaca caactatttg cagaaagata tcaaaatcat
     5341 ctggacacag ctcacttata tcctgtttca aaagtgacat ttgcaatatc ctctcttgga
     5401 gttggagtgg gatatgtaac tgtgctgttt atcggaatct gtggcttttc ttttctagtg
     5461 ggaagtctga taagtggttt tggacagtta gattatccct acccaattta tagcttagtg
     5521 aatcaagaag taactattgg gaaaatacaa gatgtattat ttcctggctt gctcttagct
     5581 ttcttagcct ttatcgtcat tgtggaagtt gtgtacttga ttgcttactt tttcaagcaa
     5641 aaaatgcctg tcctctttct ttcactcatt gggattgttg gcttattgtt tggcatccaa
     5701 accattcagc ctcttcaaag gattgcacat ctgattccct ttacttactt gcgttcagtg
     5761 gagattttat ctggaagatt acctaagcaa attgataatg tcaatctaaa ttggagcatg
     5821 ggaatggtct tacttccttg cctgattatc tttttgctag tggggattct atttattgaa
     5881 agctggggaa gttcacgtaa aaaggaagtt tttaataggt cttagcattc ttataaggaa
     5941 gttaaggaaa aactaacata gagagggaat caacttgatt ctctcttttt gattcgaaaa
     6001 ccaaaccaaa atacaaacac aaacttttca aaaaaataac tttttatctt gacaagagct
     6061 agaaaacttg gtatcattta aaagttgaga aaagcagaag tgagagcttc tcgccttgtg
     6121 acattaagtt gcctggccct acggatgaaa agtttcgaag aaacgctatc ataacgtgcg
     6181 ggcttgtata tttacgagtc cgctattgtt tttctctaat aaaacaaaag aggtgaaaac
     6241 catagcaaag caagacttat tcatcaatga tgagattcgt gtacgtgaag ttcgcttgat
     6301 tggtcttgag ggagaacagc taggcatcaa gccactcagt gaagcgcaag ctttggctga
     6361 taacgctaat gttgacctag tattgattca accccaagcc aaaccgcctg ttgcaaaaat
     6421 tatggactac ggtaagttca aatttgagta ccagaagaag caaaaagaac aacgtaaaaa
     6481 acaaagcgtt gttactgtga aagaagttcg tctaagtcca acaattgaca agggtgactt
     6541 tgatacaaaa cttcgtaatg cacgtaagtt ccttgaaaaa ggaaataaag ttaaggtatc
     6601 tattcgcttt aagggtcgta tgattaccca taaagagatt ggtgcaaaag ttttagccga
     6661 gtttgctgaa gcaactcaag atattgccat catcgaacaa cgtgctaaaa tggatggacg
     6721 tcaaatgttc atgcaattgg cgccagcgac tgacaaaaaa taattgtcag aaagttaaat
     6781 aaaggagaaa aaatcatgcc aaaacaaaaa acacaccgcg catcagctaa acgtttcaaa
     6841 cgtacaggtt ctggtggact taaacgtttc cgtgcttaca cttctcaccg tttccacgga
     6901 aaaactaaga aacaacgtcg tcatcttcgt aaagcatcta tggtgcattc aggagattac
     6961 aaacgtatca aagcaatgct tactcgcttg aaataatagc ttgactgtaa gtaaacaatt
     7021 ctaggaaata tttggaggaa ataaaacatg gcacgtgtta aaggtggcgt tgtatcacgc
     7081 aaacgtcgta aacgtattct taaattagca aaaggttact atggagctaa acacatcttg
     7141 ttccgtactg caaaagaaca agtaatgaac tcttactact atgcataccg tgaccgtcgt
     7201 cagaaaaaac gtgacttccg caaattgtgg attactcgta tcaatgcggc agctcgtatg
     7261 aacggacttt catactcaca attgatgcat ggtttgaaat tggctgagat cgaagttaac
     7321 cgtaaaatgc ttgctgactt ggctgttaac gatgcagtag ctttcacagc tcttgcagat
     7381 gcagctaaag caaaacttgg taaataacaa ctgatgagac tggaacagga ttgtccagtc
     7441 tttttaaaaa taaaggagaa agatatggct tcaaaaatgc tacacacttg cttacgagta
     7501 gaaaatcttg aaaaatcaat cgcattttat caagatgctt ttggttttaa agaattgcgt
     7561 cgcagagatt ttccagacca tgccttcacg attgtctatc taggtcttga gggtgatgat
     7621 tatgagttgg agttgactta taactacgat cacggtccgt atgtggttgg tgatgggttt
     7681 gcccatatcg ccctcagtac acctgatctt gaggcacttc atcaagaaca cagtgcaaaa
     7741 ggctatgaag tgactgagcc aaatggtcta ccaggaacta caccaaacta ttactttgtc
     7801 aaagaccctg atggatataa ggtcgaagtc attcgtgaaa aataatttcg tgcaagttaa
     7861 gtagaatatt cgttttctac ttgacttttt ttagctgaaa gagtatacta ataaaaattc
     7921 aacctttaag gggagtccag agagactcac aaggtgtcag ataaaagaat agtgcaattt
     7981 tctagaggag actttttgag tgtgctctct tgtgttgtac gattttaact gaggccttgc
     8041 actagcaagg tcttttcttt atctggtccc cttaaaattt aaggaggaaa agttatgaat
     8101 cccacatgta agaagcgttt gggtgtcatt cggttggaaa ccatgaaggt ggttgcacaa
     8161 gaggaaatcg cgccagcaat ctttgaatta gtcctagaag gagaaatggt tgaagccatg
     8221 cgagcaggcc aatttcttca tctgcgtgta ccagacgatg cccatctttt acgtcgtcct
     8281 atttcaattt cgtctattga caaggcaaac aagcagtgtc acctcattta tcggattgag
     8341 ggagctggga ctgcaatttt ttcaacctta agtcagggag acactcttga tgtgatgggg
     8401 cctcagggaa atggttttga cttgtctgac cttgatgagc agaatcaggt tctccttgtt
     8461 ggtggtggga ttggtgttcc acccttgctt gaggtggcca aggaattgca tgaacgtgga
     8521 gtgaaagtag tgacagtcct cggttttgct aataaggatg ctgttatttt gaaaacggaa
     8581 ttggctcagt atggtcaggt ctttgtaacg acagatgatg gttcttatgg catcaaggga
     8641 aatgtttccg ttgttatcaa tgatttagat agtcagtttg atgctgttta ctcgtgtggg
     8701 gctccaggaa tgatgaagta tatcaatcaa acctttgatg atcacccaag agcctattta
     8761 tctctggaat ctcgtatggc ttgtgggatg ggagcttgct atgcctgtgt tctaaaagta
     8821 ccagaaagcg agacggtcag ccaacgcgtc tgtgaagatg gtcctgtttt ccgcacagga
     8881 acagttgtat tataaggaga aaattatgac tacaaatcga ttacaagtgt ctctacctgg
     8941 tttggatttg aaaaatccga ttattccagc atcaggttgt tttggttttg gacaagagta
     9001 tgccaagtac tatgatttaa accttttagg ttctattatg atcaaggcga caacccttga
     9061 accacgtttt ggaaatccaa ctccaagagt ggcagagacg cctgctggta tgctcaatgc
     9121 aattggcttg caaaatcctg gtttagaggt tgttttggct gaaaagctac cttggctgga
     9181 aagagaatat ccaaatcttc ctattattgc caatgtagct ggtttttcaa aacaagagta
     9241 tgcagctgtt tctcatggga tttccaaggc aactaatgta aaagctatcg agctcaatat
     9301 ttcttgtccc aatgttgacc actgtaatca tggacttttg attggtcaag atccagattt
     9361 ggcttatgat gtggtgaaag cagctgtgga agcctcagaa gtgccagttt atgtcaaatt
     9421 aaccccgagt gtgaccgata tcgttactgt cgcaaaagct gcagaagatg cgggagcaag
     9481 tggcttgacc atgatcaata ctctggttgg aatgcgcttt gacctcaaaa ccagaaaacc
     9541 aatcttggcc aatggaacag gtggaatgtc aggtccagca gtctttccag tagccctcaa
     9601 actcatccgc caagtagccc aaacaacaga cctgcctatc attggaatgg ggggagtgga
     9661 ttcggctgaa gctgccctag aaatgtatct ggctggggca tctgctatcg gagttggaac
     9721 agctaacttt accaatcctt atgcctgccc tgacatcatc gaaaatttac caaaagtcat
     9781 ggataaatac ggtattagca gtctggaaga actccgtcag gaagtaaaag agtctctgag
     9841 gtaaactaca atcaatctgt tcttgatttt ttattagttt gtaatatgaa tttaggagaa
     9901 ttttggtaca ataaaataaa taagaacaga ggaagaaggt taatgaagaa agtaagattt
     9961 atttttttag ctctgctatt tttcttagct agtccagagg gtgcaatggc tagtgatggt
    10021 acttggcaag gaaaacagta tctgaaagaa gatggcagtc aagcagcgaa tgagtgggtt
    10081 tttgatactc attatcaatc ttggttctat ataaaagcag atgctaacta tgctgaaaat
    10141 gaatggctaa agcaaggtga cgactatttt tacctcaaat ctggtggcta tatggccaaa
    10201 tcagaatggg tagaagacaa gggagccttt tattatcttg accaagatgg aaagatgaaa
    10261 agaaatgctt gggtaggaac ttcctatgtt ggtgcaacag gtgccaaagt aatagaagac
    10321 tgggtctatg attctcaata cgatgcttgg ttttatatca aagcagatgg acagcacgca
    10381 gagaaagaat ggctccaaat taaagggaag gactattatt tcaaatccgg tggttatcta
    10441 ctgacaagtc agtggattaa tcaagcttat gtgaatgcta gtggtgccaa agtacagcaa
    10501 ggttggcttt ttgacaaaca ataccaatct tggttttaca tcaaagaaaa tggaaactat
    10561 gctgataaag aatggatttt cgagaatggt cactattatt atctaaaatc cggtggctac
    10621 atggcagcca atgaatggat ttgggataag gaatcttggt tttatctcaa atttgatggg
    10681 aaaatagctg aaaaagaatg ggtctacgat tctcatagtc aagcttggta ctacttcaaa
    10741 tccggtggct acatggcagc caatgaatgg atttgggata aggaatcttg gttttacctc
    10801 aagtttgatg gcaaaatggc tgaaaaagaa tgggtctacg attctcatag tcaagcctgg
    10861 tactacttca aatccggtgg ttacatgaca gccaatgaat ggatttggga taaggaatct
    10921 tggttttatc tcaaatctga tgggaaaata gctgaaaaag aatgggtcta cgattctcat
    10981 agtcaagctt ggtactactt caaatccggt ggttacatga cagccaatga atggatttgg
    11041 gataaggaat cttggtttta cctcaagtct gatggcaaaa tggctgaaaa agaatgggtc
    11101 tacgattctc atagtcaagc ctggtactac ttcaaatctg gtggctacat ggcgaaaaat
    11161 gagacagtag atggttatca gcttggaagc gatggtaaat ggcttggagg aaaagctaca
    11221 aatgaaaatg ctgcttacta tcaagtagtg cctgttacag ccaatgttta tgattcagat
    11281 ggtgaaaagc tttcctatat atcgcaaggc agtgtcgtat ggctagataa ggatagaaaa
    11341 agtgatgaca agcgcttggc tattactatt tctggtttgt caggctatat gaaaacagaa
    11401 gatttacaag cgctagatgc tagtaaggac tttatccctt attatgagag tgatggccac
    11461 cgtttttatc actatgtggc tcagaatgct agtatcccag tagcttctca tctttctgat
    11521 atggaagtag gcaagaaata ttattcggca gatggcctgc attttgatgg ttttaagctt
    11581 gagaatccct tccttttcaa agatttaaca gaggctacaa actacagtgc tgaagaattg
    11641 gataaggtat ttagtttgct aaacattaac aatagccttt tggagaacaa gggcgctact
    11701 tttaaggaag ccgaagaaca ttaccatatc aatgctcttt atctccttgc ccatagtgcc
    11761 ctagaaagta actggggaag aagtaaaatt gccaaagata agaataattt ctttggcatt
    11821 acagcctatg atacgacccc ttacctttct gctaagacat ttgatgatgt ggataaggga
    11881 attttaggtg caaccaagtg gattaaggaa aattatatcg ataggggaag aactttcctt
    11941 ggaaacaagg cttctggtat gaatgtggaa tatgcttcag acccttattg gggcgaaaaa
    12001 attgctagtg tgatgatgaa aatcaatgag aagctaggtg gcaaagatta gtactataag
    12061 tgaatatgat ttgagtgaat agtaagttaa aaatcctgat ttcaagtaaa atcaggattt
    12121 tttcatggat gcaatttttt tggagtctgg tgtgacgcgg agggtctttt gtcctgtgta
    12181 agtgacaaag ccgggttttc caccagttgg tttattgagt tttttgactt caatcatatc
    12241 tacctgcacc agattcgaca ggcgcccttg agagaagtag gcagctaact ctgctgcgtc
    12301 tgtcttgact gcatcagatg ggtcaagatt tcctgagatg acaacatggc ttccaggaat
    12361 gtccttagca tggaaccaaa gttcctcctt gcgggccatt ttaaaggtca attcctcatt
    12421 ttgaagattg tttcgtccga catagatgat ggttttgcca tcgcttgcta gatattgttc
    12481 tagttttttg cgtttctgga ttttctcccg ttgtcttctg cggataaaac ctgtttgaat
    12541 caattcttca cggatttcag cgatttcttc cagtccagct tggttgagga cggtttctac
    12601 actttccaga tagagaatag tggctttggt ttcttcaatc aaatcagtca agtatttgac
    12661 agcttctttg agtttctgat accgtttaaa atagcgttgg gcattctggt tgggagtcag
    12721 agccttatca agcgcaatca tgataggttg gttggtatag tagttgtcta ggataacctg
    12781 gtcttggtcg ttaggcactt ggtgtaggaa ggttgtcagc aattctcctt tttgacgaaa
    12841 ttcttcagcg ttgtctgtcg ccagtaactc tttttcctgt tttttgagtt tgtgtcggtt
    12901 tttctgaagt tcattttcaa cacgacgaat cagttcactg gcctgctgtt tgacgcggtc
    12961 gcgctcagcc ttatccttat agtaggtgtc caacaaatca gaaagatttg caaaaggctc
    13021 tcccacctga tttgcaaaag gaactggact gaaggaagtc tcagtcaagc atggcttggt
    13081 ttcttgattg aaaaaatttc ggaaagcgga aagtttttca ctaaccagta tcctttccaa
    13141 ttcatttgcc gtatcgcgtc ccagaccttg aaagaggctt tgaagatttt ttgctgttag
    13201 ttcttgggtt tgcaggattt caaagagctt ttcatccttg atagtaaaag gattgagaga
    13261 ttctgtactt ggcggagcga tataggtcga tcctggaagt aaggtgcggt agctattttg
    13321 tgaaaaaccg acgtgtttga taacttcgag gattttatga ctgcttttat cgaccagtag
    13381 aatattactg tgtttcccca taatttcgat aatcaaggta gcctggatat ggtctccaat
    13441 ctcgttttta ttggaaactg taatttccac aatacggtca ttttccactt gctcaatcga
    13501 ctcaatcagg gccccctgca aatactttct caaaaccatg ataaaggtag aaggttgagc
    13561 tggattttca aaagtcgttt gggtcagctg aatgcgtcca aaaactggat gggcagaaag
    13621 gagcaggcga tggctttggc gattgctgcg gatttgcaag accaactctt gttcaaaagg
    13681 ctgattgatt ttctggatgc gaccattcac taattcgctt cgcaattcct caactatgtg
    13741 gtgtaaaaaa aatccgtcaa atgacatcgt tctctccttg tgattgtatt ccatagtatt
    13801 atatcaaaaa ggtagaataa aatcatggaa atgtggtata ataaagccaa gtaaagagaa
    13861 acgagaagca catgtatatt gaaatggtag atgaaactgg tcaagtttca aaagaaatgt
    13921 tgcaacaaac ccaagaaatt ttggaatttg cagcccaaaa attaggaaaa gaagacaagg
    13981 agatggcagt cacttttgtg accaatgagc gtagtcatga acttaatctg gagtaccgta
    14041 acaccgaccg tccgacagat gtcatcagcc ttgagtataa accagaattg gaaattgcct
    14101 ttgacgaaga ggatttgctt gaaaattcag aattggcaga gatgatgtct gagtttgatg
    14161 cctatattgg ggaattgttc atctctagcg ataaggctca tgagcaggcc gaagaatatg
    14221 gtcacagctt tgagcgtgag atgggcttct tggcagtaca cggcttttta catattaacg
    14281 gctatgatca ctacactccg gaagaagaag cggagatgtt cggtttacaa gaagaaattt
    14341 tgacagccta tggactcaca agacaataaa cgaaaatgga aaaatcgtga cctgatatcc
    14401 agtttagaat ttgccatcac agggattttt actgctatca aggaagaacg aaatatgcga
    14461 aaacatgcag tgacggctct agtggtcatc cttgcaggtt ttgtttttca ggtgtcacga
    14521 atcgaatggc tctttctcct attgagcatt ttcttggtag tagcctttga gattatcaac
    14581 tctgctattg aaaatatggt ggatttggcc agtcactatc acttttccat gctggctaaa
    14641 aatgccaagg atatggcggc tggcgcggta ttagtggttt ctcttttcgc agccttaaca
    14701 ggtgcattga tttttctccc acgaatctgg gatttattat tttaaacagt aagaggaaat
    14761 tatgactttt aaatcaggct ttgtagccat tttaggacgt cccaatgttg ggaagtcaac
    14821 ctttttaaat cacgttatgg ggcaaaagat tgccatcatg agtgacaagg cgcagacaac
    14881 gcgcaataaa atcatgggaa tttacacgac tgataaggag caaattgtct ttatcgacac
    14941 accagggatt cacaaaccta aaacagctct cggagatttc atggttgagt ctgcctacag
    15001 tacccttcgc gaagtggaca ccgttctttt catggtgcct gctgatgaag cgcgtggtaa
    15061 gggggacgat atgattatcg agcgtctcaa ggctgccaag gttcctgtga ttttggtggt
    15121 gaataaaatc gataaggtcc atccagacca gctcttgtct cagattgatg acttccgtaa
    15181 tcaaatggac tttaaggaaa ttgttccaat ctcagccctt cagggaaata acgtgtctcg
    15241 tctagtggat attttgagtg aaaatctgga tgaaggtttc caatatttcc cgtctgatca
    15301 aatcacagat catccagaac gtttcttagt ttcagaaatg gttcgcgaga aagtcttgca
    15361 cctaactcgt gaagagattc cgcattctgt agcagtagtt gttgactcta tgaaacgaga
    15421 cgaagagaca gacaaggttc acatccgtgc aaccatcatg gtcgagcgcg atagccaaaa
    15481 agggattatc atcggtaaag gtggcgctat gcttaagaaa atcggtagta tggcccgtcg
    15541 tgatatcgaa ctcatgctag gagacaaggt cttcctagaa acctgggtca aggtcaagaa
    15601 aaactggcgc gataaaaagc tagatttggc tgactttggc tataatgaaa gagaatacta
    15661 agtagaggta ggctcatgcc tgcttcttgt ttttacagaa ggaggactta tgcctgaatt
    15721 acctgaggtt gaaaccgttt gtcgtggctt agaaaaattg attataggaa agaagatttc
    15781 gagtatagaa attcgctacc ccaagatgat taagacggat ttggaagagt ttcaaaggga
    15841 attgcctagt cagattatcg agtcaatggg acgtcgtgga aaatatttgc ttttttatct
    15901 gacagacaag gtcttgattt cccatttgcg gatggagggc aagtattttt actatccaga
    15961 ccaaggacct gaacgcaagc atgcccatgt tttctttcat tttgaagatg gtggcacgct
    16021 tgtttatgag gatgttcgca agtttggaac catggaactc ttggtgcctg accttttaga
    16081 cgcctacttt atttctaaaa aattaggtcc tgaaccaagc gaacaagact ttgatttaca
    16141 ggtctttcaa tctgcccttg ccaagtccaa aaagcctatc aaatcccatc tcctagacca
    16201 gaccttggta gctggacttg gcaatatcta tgtggatgag gttctctggc gagctcaggt
    16261 tcatccagct agatcttccc agactttgac agcagaagaa gcgacagcta ttcatgacca
    16321 aaccattgct gttttgaacc aggctgttga aaaaggcggt tccaccattc ggacctatac
    16381 caatgccttt ggggaagatg gaagcatgca ggattttcat caggtctatg ataagactgg
    16441 tcaagaatgt gtacgctgtg gtaccatcat tgagaaaatt caactaggcg gacgaggcac
    16501 ccacttttgt ccaaactgtc aaaggaggga ctgatgagaa aaatcatcgg aatcactggg
    16561 ggaattgcct ctggtaagtc aactgtgaca aattttctaa gacagcaagg ctttcaagca
    16621 gtggatgccg acgcagtcgt ccaccaacta cagaaacctg gtggtcgtct gtttgaggct
    16681 ctagtacagc actttgggca agaaatcatt cttgaaaacg gagaactcaa tcgccctctc
    16741 ctagctagtc tcatcttttc aaatcctgaa gagcaaaaat ggtctaagca aattcaaggg
    16801 gagattatcc gtgaggaact ggctactttg agagaacagt tggctcagac agaagagatt
    16861 ttcttcatgg atattcccct actttttgag caggactaca gcgattggtt tgctgagact
    16921 tggttggtct atgtggaccg agatacccaa gtagaacgct taatgaaaag ggaccagttg
    16981 tccaaggatg aagctgagtc tcgtctggca gcccagtggc ctttagaaaa aaagaaagat
    17041 ttggccagcc aggttcttga taataatggc aatcagaacc agcttcttaa tcaagtgcat
    17101 atccttcttg agggaggtag gcaagatgac agagattaac tggaaggata atctgcgcat
    17161 tgcctggttt ggtaattttc tgacaggagc cagtatttct ttggttgtac cttttatgcc
    17221 catcttcgtg gaaaatctag gtgtagggag tgagcaagtc gctttttatg caggcttagc
    17281 aatttctgtc tctgctattt ccgcggcgct cttttctcct atttggggta ttcttgctga
    17341 caaatacggc cgaaaaccca tgatgattcg ggcaggtctt gctatgacta tcactatggg
    17401 aggcttggcc tttgtcccaa atatctattg gttaatcttt cttcgtttac taaacggtgt
    17461 atttgcaggt tttgttccta atgcaacggc actgatagcc agtcaggttc caaaggagaa
    17521 atcaggctct gccttaggta ctttgtctac aggcgtagtt gcaggtactc taactggtcc
    17581 ctttattggt ggctttatcg cagaattatt tggcattcgt acagttttct tactggttgg
    17641 tagttttcta tttttagctg ctattttgac tatttgcttt atcaaggaag attttcaacc
    17701 agtagccaag gaaaaggcta ttccaacaaa ggaattattt acctcggtta aatatcccta
    17761 tcttttgctc aatctctttt taaccagttt tgtcatccaa ttttcagctc aatcgattgg
    17821 ccctattttg gctctttatg tacgcgactt agggcagaca gagaatcttc tttttgtctc
    17881 tggtttgatt gtgtccagta tgggcttttc cagcatgatg agtgcaggag tcatgggcaa
    17941 gctaggtgac aaggtgggca atcatcgtct cttggttgtc gcccagtttt attcagtcat
    18001 catctatctc ctctgtgcca atgcctctag cccccttcaa ctaggactct atcgtttcct
    18061 ctttggattg ggaaccggtg ccttgattcc cggggttaat gccctactca gcaaaatgac
    18121 tcccaaagcc ggcatttcga gggtctttgc cttcaatcag gtattctttt atctgggagg
    18181 tgttgttggt cccatggcag gttctgcagt agcaggtcaa tttggctacc atgctgtctt
    18241 ttatgcgacg agcctttgtg ttgcctttag ttgtctcttt aacctgattc aatttcgaac
    18301 attattaaaa gtaaaggaaa tctagtgcga gtaaaaatta atctcaaatg ctcctcttgt
    18361 gacagtatca attacctaac cagtaaaaat tcaaaaaccc atccagacaa gattgaggtt
    18421 ttaaagtatt gtcccaagga aagaaaagta accctacatc ttgaatctaa gtagatttta
    18481 tggtaaaata atagggattt taaggagttt gatatgtata acctattatt aaccatttta
    18541 ttagtattat ctgttgtgat tgtgattgca attttcatgc aaccaaccaa aaaccaatcc
    18601 agcaatgtat ttgatgccag ttcaggtgat ttgtttgaac gcagtaaagc tcgcggtttt
    18661 gaagctgtaa tgcagcgttt gacagggatt ttagtctttt tctggctagc cattgcctta
    18721 gcattgacgg tattatcaag tagataagaa aataatgggc aggactaggt ctttgcctct
    18781 ttttattttt aaaggatgtt tgagaaggtt ttacagtaaa agaaaattaa aaaatctaga
    18841 aagaaaatat gaaagataga ataaaagaat atttacaaga caagggaaag atgactgtta
    18901 atgatttggc tcaggctttg ggaaaagaca gttccaagga ttttcgtgag ttgattaaaa
    18961 ccttgtcctt aatggaaaga aagcaccaaa ttcgttttga agaagatggt agtctgacat
    19021 tagaaattaa gaaaaaacat gagattaccc tcaaggggat ttttcatgcc cataaaaatg
    19081 gctttggctt tgttagtctg gaaggcgagg aggacgacct ttttgtaggg aaaaatgatg
    19141 tcaactatgc tattgatggt gataccgtcg aggtagtgat taagaaagtc gctgaccgca
    19201 ataagggaac agcagcagaa gccaaaatta ttgatatcct agaacacagt ttgacaacag
    19261 ttgtcgggca aatcgttctg gatcaggaaa agcctaagta tgctggctat attcgttcaa
    19321 aaaatcagaa aatcagtcaa ccgatttatg ttaagaaacc agccctaaag ttagaaggaa
    19381 cagaagttct caaggtcttt atcgataaat acccaagcaa gaaacatgat ttctttgtcg
    19441 cgagtgttct cgatgtagtg ggacactcaa cggatgtcgg aattgatgtt cttgaggtct
    19501 tggaatcaat ggacattgta tccgagtttc cagaagctgt tgttaaggaa gcagaaagtg
    19561 tgcctgatgc tccgtctcaa aaggatatgg aaggtcgtct ggatctaaga gatgaaatta
    19621 cctttaccat tgacggtgcg gatgccaagg acttggacga tgcagtgcat atcaaggctc
    19681 tgaaaaatgg caatctggag cttggggttc acatcgcaga tgtttcttat tatgtgaccg
    19741 aggggtctgc ccttgacaag gaagccctta accgtgcgac ttctgtttac gtgacagacc
    19801 gagtggtgcc aatgcttcca gaacgactat caaatggcat ctgctctctc aatccccaag
    19861 ttgaccgcct gacccagtct gctattatgg agattgataa acatggtcgt gtggtcaact
    19921 ataccattac acaaacagtt atcaagacca gttttcgtat gacctatagc gatgtcaatg
    19981 atatcctagc tggcgatgaa gaaaagagaa aagaatatca taaaattgta ttaagtatcg
    20041 aactcatggc caagcttcat gaaactttag aaaacatgcg tgtgaaacgt ggagctctca
    20101 attttgatac caatgaagcg aagattttag tggataaaca aggtaagcct gttgatatcg
    20161 ttcttcggca gcgtggtatt gccgagcgga tgattgagtc ttttatgttg atggctaatg
    20221 aaacagttgc cgaacatttc agcaagttgg atttgccttt tatctatcga attcacgagg
    20281 agcctaaggc tgaaaaggtt cagaagttta ttgattatgc ttcgagtttt ggcttgcgca
    20341 tttatggaac tgccagtgag attagtcagg aggcacttca agacatcatg cgtgctgttg
    20401 agggagaacc ttatgcagat gtattgtcca tgatgcttct tcgctctatg cagcaggctc
    20461 gttattcgga gcacaatcac ggccactatg gactagctgc tgactattat actcacttta
    20521 ccagtccaat tcgtcgttat ccagaccttc ttgttcaccg tatgattcga gattacggct
    20581 gttctaagga aatagcagag cattttgaac aagtgattcc agagattgcg acccagtctt
    20641 ccaaccgtga acgtcgtgcc atagaagctg agcgtgaagt cgaagccatg aaaaaggctg
    20701 agtatatgga agaatacgtg ggtgaagagt atgatgcagt tgtatcaagt attgtcaaat
    20761 tcggtctctt tgtcgaattg ccaaacacag ttgaaggctt gattcacatc actaatctac
    20821 ctgaatttta tcatttcaat gagcgtgatt tgactcttcg tggagaaaaa tcaggtatca
    20881 ctttccgagt gggtcagcag atccgtatcc gtgttgaaag agcggataaa atgactggag
    20941 agattgattt ttcattcgta cctagtgagt ttgatgtgat tgaaaaaggc ttgaaacagt
    21001 ctagtcgtag tggcagaggt cgtggttcaa atcgtcgttc ggataagaag gaagacaaga
    21061 gaaaattagg acgctcaaat gataagcgta agcattcaca aaaagacaag aagaaaaaag
    21121 gaaagaaacc tttttacaag gaagtagcta agaaaggagc caagcatggc aaagggcgag
    21181 ggaaaggtcg tcgcacaaaa taaaaaggca cgccacgact atacaatcgt agatacgcta
    21241 gaggcaggga tggtcctgac tggaactgaa atcaagagtg tacgagctgc tcgaattaat
    21301 ctcaaggatg gctttgctca agtgaaaaat ggagaagttt ggctgagcaa tgttcatatc
    21361 gcgccttacg aagagggcaa tatctggaac caggaaccag aacgtcgtcg taaactcctg
    21421 cttcataaaa agcaaattca aaaattggaa caagagacca aagggacagg aatgacctta
    21481 gttcccctta aggtctatat aaaagatggc tacgctaagc ttcttttagg acttgccaaa
    21541 gggaagcatg actatgacaa acgggagtct atcaaacgtc gtgagcaaaa tcgagatatc
    21601 gcgcgtgtga tgaaagctgt taatcagcga taaaaagagg aattgaaaat ggaaaaatca
    21661 gttgcctata aacgcatgcc tttgtggaat aaacaaacaa tgcctgaagc tgttcagcaa
    21721 aagcacaata caaaagttgg gacttggggg aaaattactg tcttgaaggg agctctcaag
    21781 tttattgaat tgacagaaga aggggaagtt ctagctgaac acctctttga agcaggggca
    21841 gacaatccaa tggcccaacc tcaagcctgg caccgagtgg aagctgccac agatgatgtg
    21901 gaatggtact tggaatttta ttgtaaacct gaggattatt ttgctaaaaa atacaatacc
    21961 aatcctgttc attcagaggt cctagaggcc atgcagacag tgaaacaagg gaaagctttg
    22021 gatttgggtt gtggtcaggg gcgtaattct ctttttctag cccagcaaga ttttgatgtg
    22081 acggctgtag atcaaaatgg actagctctt gaaatcttgc aaagcattgt ggagcaggaa
    22141 gatttggaca tgcctgttgg cctttacgat atcaattcag ctagcattga acaagaatat
    22201 gattttatcg tttcaacagt tgttctcatg tttctacaag cggaccgcat tccagctatt
    22261 attcaaaata tgcaggagaa aaccagtgtt ggtggttaca accttatcgt ttgtgccatg
    22321 gacacggagg attatccttg ctcggttaac ttcccattca cctttaaaga aggagaactg
    22381 gcagactatt acaaggattg ggaattggtt aagtacaatg aaaatccagg ccatttgcac
    22441 cgtcgcgatg agaatggcaa tcgtattcaa ctacgctttg cgaccttact agctaagaaa
    22501 atcaagtaaa cacacatgaa gattaggaat tttcctgatc ttttttcttt tttacgaatg
    22561 atatagaaaa ggagggaatt catgtttgtt gcgagagatg ctaggggaga attggtaaat
    22621 gtgttagagg ataaacttga gaagcaagca tacacctgcc cagcttgtgg aggccagatc
    22681 catttgcgtc aaggaccaag tgtacggacg cattttgccc ataaatcctt aaaagactgt
    22741 gattttttct ttgaaaatga aagtccagaa cacatagcca ataaggaatc cctctatcac
    22801 tggttgaaaa aagagacaaa ggttcaatta gagtacccgc tttcagaact taaacagatt
    22861 gcggatgtat ttgtaaatgg caatctagct ctagaagttc agtgtagtcc cttgcctcag
    22921 aaagtcctta aagagcgaag tgagggctat cgtagtcagg gttaccaagt actgtggttg
    22981 ctgggtcaaa aactgtggct caaggagcgt ttgactcgtc tacagcaagg ttttctttat
    23041 ttcagtcaaa acatgggctt ttatgtttgg gaattagaca aggaaaaaca agttttaaga
    23101 ctcaaatacc tgatttacca ggatctccgc ggtaaactcc attatcaaat caaggaattt
    23161 tcctatggtc aaggtagttt attggaaata ttgcgtcttc cctataagag acaaaaaata
    23221 tctcatttta cagtttctga ggacaaggac atctgtcgct atatccggca acaactttat
    23281 tatcaaaatc tcttttggat gaaagaacaa gcagaagcct atcaaaaggg agaaaatatc
    23341 ctgacttatg gactgaaaga atggtatcca caaattcgac caatagtggg caaatttttc
    23401 cagattgaac aagacttgac tagctattat cagcactttt atacctatta ccaaaaaaat
    23461 cctcaaaatg attggcaaaa gctttatcca ccagcctttt atcagcaata tttcttgaaa
    23521 aatatggtag aatagaaagg atggaggaat ctaatggtat tacaaagaaa tgaaataaat
    23581 gaaaaagata catgggatct atcaacgatc tacccaactg accaggcttg ggaagaagcc
    23641 ttaaaagatt taacagaaca attggagaca gtagcccagt atgaaggcca tctcttggat
    23701 agtgcggata acctactaga aatcactgaa ttttctcttg aaatggaacg ccagatagag
    23761 aagctttacg tttatgctca tatgaagaat gaccaggata cacgtgaagc taagtatcaa
    23821 gagtactatg ccaaggccat gacactctac agccagttag accaagcctt ttcattctat
    23881 gagcctgaat ttatggagat tagcgaaaag cagtatgctg actttttaga agctcaacca
    23941 aagctgcagg tttatcaaca ctattttgac aagctcttgc aaggcaagga tcacgttctt
    24001 tcacaacgtg aagaagaatt attggctgga gctggagaaa tctttggttc agcaagtgaa
    24061 accttcgcta tcttggacaa tgcggatatt gtgttccctt atgtcctaga cgatgatggt
    24121 aaagaagttc agctatctca tgggacttac acacgtttga tggagtctaa aaaacgtgag
    24181 gttcgccgtg gtgcctatca agctctttat gcgacttacg aacaattcca acacacctat
    24241 gccaaaacct tgcaaaccaa tgttaaggtg caaaattacc gtgctaaagt tcgtaactac
    24301 aagagtgctc gtcatgcagc cctcgcagcg aattttgttc cagaaagtgt ttatgacaat
    24361 ttggtagcag cagttcgcaa gcatttgcca ctcttacatc gctatcttga gcttcgttca
    24421 aaaatcttgg ggatttcaga tctcaagatg tacgatgtct acacaccgct ttcatctgtt
    24481 gaatacagtt ttacctacca agaagccttg aaaaaagcag aagatgcttt ggcagtcttg
    24541 ggtgaggatt acttgagccg tgttaaacgt gccttcagcg agcgttggat tgatgtttac
    24601 gaaaatcgag gcaagcgttc aggtgcctac tctggtggtt cttacgatac caatgccttt
    24661 atgcttctca actggcagga caatctggac aatctcttta ctcttgttca tgaaacaggt
    24721 cacagtatgc attcaagcta tactcgtgaa actcagcctt atgtttacgg agattactct
    24781 atctttttgg ctgagattgc ctcaactacc aatgaaaata tcttgacgga gaaattattg
    24841 gaagaagtgg aagacgacgc aacacgcttt gctattctca ataacttcct agatggtttc
    24901 cgtggaacaa ttttccgcca aactcaattt gctgagtttg aacacgccat tcaccaagca
    24961 gatcaaaatg gggaggtctt gacaagcgat ttcctaaata aactctacgc agacttgaac
    25021 caagagtatt atggtttgag taaggaagac aatcctgaaa tccaatacga gtgggctcgc
    25081 attccacact tctactataa ctactatgta tatcaatatt caactggctt tgcggccgcc
    25141 tcagccttgg ctgaaaaaat tgtccatggt agtcaagaag accgtgaccg ctatatcgac
    25201 tacctcaagg caggtaagtc ggactatcca cttaatgtca tgagaaaagc tggtgttgat
    25261 atggagaagg aagactacct caacgatgcc tttgcagtct ttgaacgccg tttaaatgag
    25321 tttgaagccc ttgttgaaaa attaggattg gcataaaatg gttgaatcgt atagtaagaa
    25381 tgctaaccat aacatgcgtc gtcctgtcgt caaagaagaa attgtagact tgatgcgtca
    25441 gcgtcaaaag caggtcacag gtttcttgaa agaattggaa gactttgccc gcaaggaaaa
    25501 tattcctatt attccccatg aaacggttgc ttatttccgt tttattatgg aaaccatgca
    25561 gcctaaaaat attctggaaa ttgggacggc tatcggtttt tcagctctct tgatggctga
    25621 acatgcgcca aatgctaaga ttacaactat tgatcgtaat ccagaaatga ttggttttgc
    25681 caaggaaaat tttgcccagt ttgacagtcg caagcaaatc actctcctag agggagatgc
    25741 ggtggatgtc ttatctacac tgacagagtc ttatgatttc gtatttatgg attctgccaa
    25801 gtctaaatac atcgtctttc tgccagaaat cctcaaacat ttggaagttg gtggtgtggt
    25861 tgtcttggat gatatttttc aaggtggtga tgttgccaag gatattatgg aagtccgtcg
    25921 tggtcagcga accatttatc gaggccttca aaaattattt gatgcaacct tagacaatcc
    25981 agaactcacc gcaacattag tgcctttagg agatggtatt ctcatgcttc gtaaaaatgt
    26041 agcagatgtt caactgtctg aaagcgaatg attttcagaa aaatttaaga aaaaatagta
    26101 aaatagatag agtaacactt atctcaaagg agtagacatg aagaaaaaat tattggcagg
    26161 tgccatcaca ctattatcag tagcaacttt agcagcttgt tcgaaagggt cagaaggagc
    26221 agaccttatc agcatgaaag gggatgtcat cacagaacat caattttatg agcaagtgaa
    26281 aaacaaccct tcagcccaac aagtcttgtt aaatatgacc atccaaaaag tttttgaaaa
    26341 acaatatggc tcagagcttg atgataaaga ggttgatgat actattgccg aagaaaaaaa
    26401 acaatatggc gaaaactacc aacgtgtctt gtcacaagca ggtatgactc ttgaaacacg
    26461 taaagctcaa attcgtacaa gtaaattagt tgagttggca gttaagaagg tagcagaagc
    26521 tgaattgaca gatgaagcct ataagaaagc ctttgatgag tacactccag atgtaacggc
    26581 tcaaatcatc cgtcttaata atgaagataa ggccaaagaa gttctcgaaa aagccaaggc
    26641 agaaggtgct gattttgctc aattagccaa agataattca actgatgaaa aaacaaaaga
    26701 aaatggtgga gaaattacct ttgattctgc ttcaacagaa gtacctgagc aagtcaaaaa
    26761 agccgctttc gctttagatg tggatggtgt ttctgatgtg attacagcaa ctggcacaca
    26821 agcctacagt agccaatatt acattgtaaa actcactaag aaaacagaaa aatcatctaa
    26881 tattgatgac tacaaagaaa aattaaaaac tgttatcttg actcaaaaac aaaatgattc
    26941 aacatttgtt caaagcatta tcggaaaaga attgcaagca gccaatatca aggttaagga
    27001 ccaagccttc caaaatatct ttacccaata tatcggtggt ggagattcaa gctcaagcag
    27061 tagtacatca aacgaatagt ccaaatcaat gagtcaggga aaaaactcga cttcaggaaa
    27121 aaatgaagca aacattccca caataaaacg catagtacaa ggtttgtact gccccccaaa
    27181 aaagttagac aattaattta tccgaaggat ttagttctgt attgcacaga gctaagtcct
    27241 tttagtttta tcttaattct cttattgttg taataatcaa tatagtctat aatggcttgt
    27301 tccaattgat taagtgattt aaatgtttgc tcatagccat aaaacatttc ggattttaaa
    27361 atgccaaaga aagattccat cctaccgttg tcttggctgt ttcctttgcg tgacatagat
    27421 gcttgaattc ccttactctc taggaagcga tgataagaat cgtgttggta ttgccagcct
    27481 tggtcactat ggagaatcgt attctcgtag tgcttctctt tgaatgcctg ttccaacatt
    27541 aacgatcaat caatttaatc atatacctaa gattagaatt gtttatccca aatttatttg
    27601 aaagcttctc taagctatat ccttgttttc taagttcata gatctgaact ttatcatcat
    27661 aattcaattt cataataaaa acaccccaaa agttagattt tttctgtcta acttttgggg
    27721 tgtagttcat gtacacctga tatgatgcgt tttataattt taaagacttt ttgaccagcc
    27781 tcatttttta acttgatact cagtgaaaag caaagattaa actaggaagc tagctgtagg
    27841 ctgctcaaag aacagctttg aggttgcaga taaaacttgt gaggtaacca acatatataa
    27901 tgtgaagctg acgtggtttg aatagatttt aggagggtat gagtctggaa gttttaatgg
    27961 ataatgcaag attccataga atgggtaagc tagagttctt atgtgaagag tttgggcata
    28021 aacttttacc ttttcctccc tactcatctt agtatagaaa agtgaatctg aaatagtaca
    28081 taactgcttc taaaacattc ttataaattg atttaaattc tcaaatcata ttattcagtt
    28141 cttatttcat tttgctctac aatcctgttg agaagacacg tgttcatatc aaaaaggtat
    28201 tggcaagttg caataccttt ttacaaggtt cttttgtctt atttttgttt caactgacta
    28261 tatctcctat ggttctagtt cagaaggcta ggctataatt atgattgata agaagtatca
    28321 ttccaagtat tgagagtgaa tgtttcaaaa tcatgggttt ctataatggt caggctggca
    28381 tttgctagac cgccatcttt acgaagaagt ggttctttat agcctaggag agtacgaaga
    28441 ctggcagtaa gattggcgcc gtgtccgaca attagaatac gctcagctgg actatctttt
    28501 aatgatttga taaattggat ggtccgctga gttgtactat agagggattc ggctccgaac
    28561 attcgagtgt caaattgagc aagatttgaa cgaaaagcct ggatttgttg cgggtaaata
    28621 gcttccaggg ttgcaatttt caaaccttct aacttcccaa gttgccattc acggagatta
    28681 ggaacgattt ctaaagaaca gggggtatgg agttgacttt ggataatctc agcagatttg
    28741 accgctcgag gtaaatcact tgaataaatc tgatcaaaag gaatttcctt gagatactgg
    28801 ccaagtcgtt ttagggtttc aatggattca ggaagaagag gagaatcacc actagcacct
    28861 tgaaaacgac cttcttggtt ccagagggta cgaccgtggc ggacaaagta gagtttcatt
    28921 acttgatgtc ctccaaaata tctacaaagt ctgcctttac aaagctagcc aagtcttgtg
    28981 gcgcgacgat aatgctgtgt ccgacttcgc ctgcagagac aatcatttga tccaaatcta
    29041 gagcaatttt atcgataaaa atgggataat tgtgtttctg acgaattccg acaggattat
    29101 tggctccatg aatgtaacca gttgtttttt ctaagtcctt ttgtggaatc atgctcactt
    29161 ttttattgcc agaaatttta gctagtttct tttcagacaa gtgctgagtg atagggacaa
    29221 ttccgataat cggtccggtc ttgtctccca aaagcgccaa ggttttgaaa atctgatctc
    29281 gttcataacc ttgaggaagc tctccttcta gggcattgat ttgaatcccc tgatgaggga
    29341 tagctgcttt agataggatt tgttccacca atgttttttt gattttaact ttttttgcca
    29401 ttatttatat ttatcctcca attgactcat ccaaatacca agccagattc ccagcgcaaa
    29461 gaagaaggcg atgatgacat aaccgacaag tgaaagtcct gtgtattgga tactttcagc
    29521 gtttcctgca tttggaatta agatcaaaag ggtacttgat aggacgatac cgatgatgaa
    29581 atgatagacg cgtgagtggt agttgtttaa ggcataatcc atcaattttg aaaaaacgat
    29641 gagagttgca cctgcaccaa ttccaatcgg aaagaaggtt cccaagagat caaaagtttt
    29701 aaaaccagtc aacataggag catagagtcc caaaatcaaa agtaaatttg atggactgag
    29761 gccaggaacc aagacgccaa gggccaatag tgcgcctgct aggacgaagt taagaaagct
    29821 ggcgcttaag gttccaacga caaaatttaa ggcatagagt cctaatccag aaatgataaa
    29881 ggttgtccat aaccaagcta aatcaatctt gtctcggtca gattctcgag ttgattcttt
    29941 gaggaggcta ggaactgtac cgataatagc tcccgcaaag ctccataata caaaaacctg
    30001 ataattttca agcaggtatt caatcgggta ggaaaataag ccgattccca gaagcatacc
    30061 gatggcaact ggaataaagt acaaaacatt ttctttaaag tctttaaagg gatgggccag
    30121 aaagccaatc attcgttcat agattcctaa gattgctgct agaacccctc cggaaattcc
    30181 cggtaggata aatccaagag caattacaat ccctttaata acgcgtgcta accatgagag
    30241 catatatttc ctccaactat ttctatttca aaaaatcctt actatattgt atcacaatca
    30301 gacacaaaaa gaaaaagcaa atgataaaca aatgctttta aggttttaaa aaaagttttc
    30361 gaaaggtttc ttctttattt tttaagggag agataacgtt gatatctaaa tcgtggtcaa
    30421 agccggcaat ttttccttta gatgtgtatt ggtgaatatc ataatctaaa tcagttttag
    30481 gactgctctc caaaaatcct gagtctgagc cgtaggacgg aatccaaaca gaggtaaact
    30541 tgcctgtatc aatactgtgt tcttccatga agtagacacc aacgtagatg ccgatgtttt
    30601 tagcacctag tgatgctagt tttgctcgaa agttttcgac accttcgttc atattagaca
    30661 tggttttgtc ttccacgtca agccaatagt aactagggct gtaaggagag gcagcattgt
    30721 agaaaacttc ggcagccttt tccatttctt ggacactttt tccagctaca taagcgtaga
    30781 cagcaactgg gacattccgc ttttgaagtt cagtgatatg actcttatag gccttgtcta
    30841 ttccattgat aaatgaagca tcattttctt ttgttgtttg agcaccactg tgaacacgaa
    30901 caatagcacc tgaaatattt tgtgagaggg catcgtagtt gatttcctca ggatgctgcc
    30961 agccagagag gtcaataatc ggtttgtcta agtgtttcaa agcctgtgct atattggatt
    31021 ttgttttaaa cgattggctg tcattaagtg ggcgattgat gattaaaatg aacatcataa
    31081 tcccaaaaaa actaaataaa ataagtggat gaatttgttt tctcatatct tataagtcta
    31141 ccctaaaaat caaaaaaaat caaaaaaaat caaaaaaatg ggttaaggaa gagactttag
    31201 agcatttttt cattcaagag tgcggaatga tttgaaatat ggtataataa aagggaattt
    31261 ctacagaaaa gagaagatta tgtcaaattt tgccattatt ttagcagcgg gtaaagggac
    31321 tcgcatgaaa tctgatttgc caaaagtttt gcacaaggtt gcgggtattt ctatgttgga
    31381 acatgttttc cgtagtgtgg gagctatcca acctgaaaag acagtaacag ttgtaggaca
    31441 caaggcagaa ttggttgagg aggtcttggc tggacagaca gaatttgtga ctcaatctga
    31501 acagttggga actggtcatg cagttatgat gacagaacct atcttagaag gtttgtcagg
    31561 acacaccttg gtcattgcag gagatactcc tttaatcact ggtgaaagct tgaaaaactt
    31621 gattgatttc catatcaatc ataaaaatgt ggccactatc ttgactgctg aaacggataa
    31681 tccttttggc tatggacgaa ttgttcgtaa tgacaatgct gaggttcttc gtattgttga
    31741 gcagaaggat gctacagatt ttgaaaagca aatcaaggaa atcaacactg gaacatacgt
    31801 ctttgacaac gagcgtttgt ttgaggcttt gaaaaatatc aataccaata acgctcaagg
    31861 cgaatactat attacagacg tcattggtat tttccgtgaa actggtgaaa aagttggcgc
    31921 ttatactttg aaagattttg atgaaagtct tggggtaaat gaccgtgtgg cgcttgcgac
    31981 agctgagtca gttatgcgtc gtcgcatcaa tcataaacac atggtcaacg gtgttagctt
    32041 tgtcaatcca gaagcaactt atatcgatat tgatgttgag attgctccgg aagttcaaat
    32101 cgaagccaat gttaccttga aagggcaaac gaaaattggt gctgagactg ttttgacaaa
    32161 tggtacttat gtagtggaca gcactatcgg agcaggagcg gtcattacca attctatgat
    32221 tgaggaaagt agtgttgcag acggtgtgac agtcggtcct tatgctcaca ttcgtccaaa
    32281 ttcaagtctg ggtgcccaag ttcatattgg taactttgtt gaggtgaaag gatcttcaat
    32341 cggtgagaat accaaggctg gtcatttgac ttatatcgga aactgtgaag tgggaagcaa
    32401 cgttaatttc ggtgctggaa ctattacagt caactatgac ggcaaaaaca aatacaagac
    32461 agtcattgga gacaatgtct ttgttggttc aaattcaacc attattgcac cagtagaact
    32521 tggtgacaat tccctcgttg gtgctggttc aactattact aaagacgtgc cagcagatgc
    32581 tattgctatt ggtcgcggtc gtcagatcaa taaagacgaa tatgcaacac gtcttcctca
    32641 tcatcctaag aaccagtagg agcctatcat ggagtttgaa gaaaaaacgc ttagccgaaa
    32701 agaaatctat caaggaccaa tatttaaact ggtccaagat caggttgaat taccagaagg
    32761 caagggaact gcccaacggg atttgatttt ccacaatggg gctgtctgtg ttttagcagt
    32821 aacggatgaa caaaaactta tcttggtcaa gcagtaccgc aaagctatcg aggctgtctc
    32881 ttacgaaatt ccagccggaa aattggaagt aggagaaaac acagcccctg tggcagctgc
    32941 ccttcgtgaa ttagaggaag aaacagccta tacagggaaa ttagaactct tgtacgattt
    33001 ttattcagct attggctttt gtaatgagaa gttaaaacta tatttagcaa gcgatttaac
    33061 aaaagtggaa aatccgcgtc cgcaggatga gaatgaaacc ttggaagtcc ttgaagtgag
    33121 cttagaagaa gcgaaagaat taatccaatc aggtcgtatt tgtgatgcca agacaattat
    33181 ggctgttcag tattgggagt tgcagaaaaa atagaggagg tcagtatggg taaatcttta
    33241 ttaacggatg aaatgattga aagagctaat agaggcgaaa aaatttcagg tcctcctttg
    33301 ctagatgata atgaggaaac taagatttta ccaacctctt cttcccgttt tggttatgcc
    33361 aatcctaagg atcatggttt tagccaggaa accttgaaga ttcaggtcga accatctatt
    33421 cataaaagcc gtcgtattga aaataccaag agaaatgtct tcaattctaa gttgaataaa
    33481 atcttatttg cggtcatctt tctcttgatt ttgcttgttt tagcaatgaa acttttgtaa
    33541 tagaaaagga attgaaatga aaataggaat tattgctgct atgccggaag aactggctta
    33601 tctggtccag catttagata atgcccagga gcaagttgtt ttggggaata cctatcatac
    33661 aggaaccatt gcttctcatg aagtcgttct tgtagaaagt ggaattggta aggtcatgtc
    33721 tgctatgagt gtggcgattt tggctgatca tttccaggtg gatgccctta ttaatacggg
    33781 ttcagctggg gcagtagcag aaggtatcgc tgttggggat gtcgtgattg ctgacaaatt
    33841 agcctatcat gacgtggatg tcacagcttt tggctatgct tatggacaaa tggcgcaaca
    33901 accgctttat ttcgaatcag acaaaacctt tgttgctcaa atccaagaga gtttatctca
    33961 attggaccaa aactggcatc ttggtttgat tgctacagga gatagttttg ttgcaggaaa
    34021 tgacaagata gaagcgatta agtcccattt cccagaagtt ttagccgtgg agatggaggg
    34081 ggcagctatt gctcaagcag cgcatgccct caatctccca gtcttagtca tccgagctat
    34141 gagtgacaat gccaaccatg aagcaaacat cttttttgat gagtttatta tcgaagctgg
    34201 acgtcgctct gcccaagtct tgttggcctt tttgaaggct ttagattaag cggaaatttg
    34261 acagtttttc tagcttatga taagatttaa gtaaagaaaa gctagaaaac gtttcagagg
    34321 atattatgag tattgaaatg accgtcagtg agattgcaga ggtcttagga ttatctcgcc
    34381 aagcaatcaa taaccgtgtc aaagaattac cagaagaaga cacagataaa aatgacaaag
    34441 gggtaacagt tgttaccaga agtggcttga ttaagctaga agaaatctat aaaaaaacga
    34501 tttttgaaga tgagcctgtc agtgaagatg tcaaacaacg tgaactgatg gagattctag
    34561 tggatgagaa gaatgcagaa attcttcgtc tttatgaaca attaaaagcc aaggatcgtc
    34621 agttatcaga aaaagacgag cagatgcgta tcaaagaccg tcagattgct gagaaagaca
    34681 aacaattaga tcagcaacaa caattgaccc ttcaagccat gaaggatcaa gaaaatctta
    34741 agctagagct ggaccaagca aaagaagaag tccaatccac taaaaaaggc ttttttgctc
    34801 gtttatttgg aggataatca aggagctgtt taggttaaat gctaacctga tggcttcttt
    34861 tgtttgtgaa tagtatagtt gattagaaca gagacagtag aggagaggta cagaatggaa
    34921 cgattagaag attacattgc ttttgattta gaatttaatc agcacgaagg acaaacacac
    34981 ttgattcaag catcggcagt gcgttttaga gatggtcggg aaatcgatgc ctatgattcc
    35041 tatgttcata ccagcgtccc tctaaaaagc tttatcaatg gtttgaccgg gattacagct
    35101 gagaccttaa aagatgctcc tccagttgag aaagtcttag aagaattcca agagtttgtg
    35161 ggttctttgc tgatgatagg ctacaatgct gctaaaagtg atttacctat tttagcagag
    35221 catggtttag actatagcca acagtacaag gtggatttgt atgatgaagc ttttgaacgt
    35281 cggagttcag atttacatgg tattgccaat ctcaaattgc aaactgttgc ctcatttctt
    35341 ggatttcaag gtcagtctca taatagttta gaggatgctc ggatgacggc gcgtgtttac
    35401 gaatccttct tagagtcgga tcaagctagg gaattgttag agacagaaag tagcttatca
    35461 aacaatcctt ttggtggctt ggacttgtct caattatttg actaggagtg cctatgaaac
    35521 ctgaaaaacc taaaaaattg ggtcttaaac agatttacct caatcttgat aaaatcctct
    35581 ttctattttt cttgattttt atgatagtgg agtatttgtg ggtaccattc aattcatggt
    35641 tggctagctt cttattagat cagacaggtt atctttttat ttcctataac aatgtcttag
    35701 ccatccttac tcattctcca ttgattagtc tagctttttt agccttgatt gtaattaacc
    35761 ttctggttgc ttattttcaa ataggactcc tctttattgg tgctcgtcat ctcctctata
    35821 atgaaaagcg aaggctaatt gagtatatcc gcaaggtttt ccatgaaagt tttggattta
    35881 tgaaaaagct aacttgtgct aaagccttgt ttatcttttt ctatatagct atgctttttc
    35941 cttttatacg gaaaatgctg aagatttatt atcttaataa aatcgtcatt ccagagttta
    36001 tccaagctta tttagaagat aaatattgga tgtggtggct gagcatccta cttctatctc
    36061 ttatctttct ctatgtctct gtcagattga tgtttgccct tccgaagatt gtatatgatc
    36121 agctgactgt tcgagaagca gtgatgttta gcttggagaa aaccaagaag agagttactt
    36181 tttatgcttg gaatttattt tacatcttgc tcaaagcaca tttattattt tatcttcctt
    36241 tgattccttt attattggct caaactttgg tagatgatat cactcagaga gagtctctga
    36301 ttcttggtat tttgaatttt gtcgtgatta aaaatctcta ttatatggct ctgacttatt
    36361 ttttggttaa atttgtttca tttttgacag gaaaggagct ggatatgctt cctaggagag
    36421 aaaaagatca catcgtgcga tggggtgtca tgacttgtgc cagtcttttc tttgccttag
    36481 aaggttatat ttatctggag gctcccatgg ttcatctacc tcaacttatt tctcaccgag
    36541 gggtttccaa tgcaaatggg attcaaaata cagtagagtc cttggaaact acagcacaac
    36601 tcaaaccaga cttggtggag acggacgtgc aggaaacaaa agatgggcag tttgtcatga
    36661 tgcatgatgc taacttgaaa aatctagcag gtatcaataa aagtcctcaa gacttaaact
    36721 tggaggagct taaagggatt gatatttttg aaaatggcta ccagactaaa atttcaagct
    36781 ttgaagatta tctcagtcga gccaacgaac ttggtcaaaa attactaatt gaaattaaaa
    36841 ccagtaaaaa agatagtcca gacatgatga accgcttttt agcccgttat gctgcaaagc
    36901 tcaagattta tggacatcaa atccagtctt tagactacca tgttgtcgaa aaagtaagac
    36961 agtatgatgc cgaactgcca gtttatttca tcatgcccta caattctgta tttcctaaaa
    37021 caagagcgac aggatatact atggagtact caaccttgga tgaatatttt gtaagcaaac
    37081 tatggacaac ggatcagaaa ctttatgtct ggactgtcaa tgattcagaa gctatcagca
    37141 aatctcttca cttaggagta gatggagtga ttacagatga tttggaaaaa gttcagcggg
    37201 aaatagaagt agcccaagaa gatccagaat atacggattt gctcttgaaa aaagcattgg
    37261 aattctttga attttagtaa taaaaaagag gaactgttgt tcctcccatg ataggtaagt
    37321 attcttgtga atgcttgctt ttttgtggtt gcaatccgtt tacgagaatt gtttgtattg
    37381 ttcttgtttc aatttacttt atagtgcttt gaagttggaa tgctacacta taacttcta
//
LOCUS       DBEROT010000018        36212 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.18, whole genome shotgun sequence.
ACCESSION   DBEROT010000018 DBEROT010000000
VERSION     DBEROT010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.18"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..650
                     /locus_tag="ACL8CG_001063"
     CDS             <1..650
                     /locus_tag="ACL8CG_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGS1343670.1"
                     /translation="NPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGN
                     KTKGWYRRIMIVPFNADFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPK
                     AVKGLLEEYQEDNDYLLSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNV
                     YGAGKETIKHLQQLTPNRYSLRKKRVPSEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            991..1158
                     /locus_tag="ACL8CG_001064"
     CDS             991..1158
                     /locus_tag="ACL8CG_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343671.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEINDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            1241..1771
                     /locus_tag="ACL8CG_001065"
                     /pseudo
     CDS             1241..1771
                     /locus_tag="ACL8CG_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1842..2099
                     /locus_tag="ACL8CG_001066"
     CDS             1842..2099
                     /locus_tag="ACL8CG_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343672.1"
                     /translation="MKRLAIETITKPMKLRGISKGIAELDGQRLEIDLDNLMIDFGGE
                     SFELDRIAGTKGGNRYFFALIVGDGAGCFINGIYILVAVLV"
     gene            3028..3438
                     /locus_tag="ACL8CG_001067"
     CDS             3028..3438
                     /locus_tag="ACL8CG_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HGS1343673.1"
                     /translation="MTPEQVKEKLEGVKWINKEIEGLYLELAALESGIIKKQELSNTR
                     VQTSRVNTTENNPISVLKLKEDTLQRIERLNEERMEISRLIDKLANPLERSVLRLFYL
                     NVLDAWQVAEEIDKSKTAVYIIRQKAIEHLANVG"
     gene            3594..3986
                     /locus_tag="ACL8CG_001068"
     CDS             3594..3986
                     /locus_tag="ACL8CG_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGS1343674.1"
                     /translation="MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLP
                     YRWDLSGEHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATS
                     STSYHRYKQIAVLNFARIHQNGELEVYK"
     gene            4040..4198
                     /locus_tag="ACL8CG_001069"
     CDS             4040..4198
                     /locus_tag="ACL8CG_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343675.1"
                     /translation="MIEDFLIDLENIQLEDMEIDFNMDIDIDLNIDFEIDVDLDDLDL
                     TLLQELEA"
     gene            complement(4627..4821)
                     /locus_tag="ACL8CG_001070"
     CDS             complement(4627..4821)
                     /locus_tag="ACL8CG_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGS1343676.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANCWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(4886..6022)
                     /gene="dnaN"
                     /locus_tag="ACL8CG_001071"
     CDS             complement(4886..6022)
                     /gene="dnaN"
                     /locus_tag="ACL8CG_001071"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGS1343677.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(6181..7542)
                     /gene="dnaA"
                     /locus_tag="ACL8CG_001072"
     CDS             complement(6181..7542)
                     /gene="dnaA"
                     /locus_tag="ACL8CG_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGS1343678.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(7755..8513)
                     /locus_tag="ACL8CG_001073"
     CDS             complement(7755..8513)
                     /locus_tag="ACL8CG_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGS1343679.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(8571..9752)
                     /locus_tag="ACL8CG_001074"
     CDS             complement(8571..9752)
                     /locus_tag="ACL8CG_001074"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGS1343680.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            9935..10414
                     /gene="rlmH"
                     /locus_tag="ACL8CG_001075"
     CDS             9935..10414
                     /gene="rlmH"
                     /locus_tag="ACL8CG_001075"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGS1343681.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            10458..10531
                     /locus_tag="ACL8CG_001076"
     tRNA            10458..10531
                     /locus_tag="ACL8CG_001076"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10492..10494,aa:Arg,seq:tct)
     gene            10696..10821
                     /gene="comC"
                     /locus_tag="ACL8CG_001077"
     CDS             10696..10821
                     /gene="comC"
                     /locus_tag="ACL8CG_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGS1343682.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            10842..12167
                     /gene="comD"
                     /locus_tag="ACL8CG_001078"
     CDS             10842..12167
                     /gene="comD"
                     /locus_tag="ACL8CG_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGS1343683.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVLGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            12164..12916
                     /gene="comE"
                     /locus_tag="ACL8CG_001079"
     CDS             12164..12916
                     /gene="comE"
                     /locus_tag="ACL8CG_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGS1343684.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            12968..13039
                     /locus_tag="ACL8CG_001080"
     tRNA            12968..13039
                     /locus_tag="ACL8CG_001080"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13001..13003,aa:Glu,seq:ttc)
     gene            13045..13118
                     /locus_tag="ACL8CG_001081"
     tRNA            13045..13118
                     /locus_tag="ACL8CG_001081"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13079..13081,aa:Asn,seq:gtt)
     gene            complement(13159..13701)
                     /locus_tag="ACL8CG_001082"
     CDS             complement(13159..13701)
                     /locus_tag="ACL8CG_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS1343685.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            13880..15483
                     /locus_tag="ACL8CG_001083"
                     /pseudo
     CDS             13880..15483
                     /locus_tag="ACL8CG_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(15513..18065)
                     /locus_tag="ACL8CG_001084"
     CDS             complement(15513..18065)
                     /locus_tag="ACL8CG_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGS1343686.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMGFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIRFHVKLIYIIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(18127..19749)
                     /locus_tag="ACL8CG_001085"
     CDS             complement(18127..19749)
                     /locus_tag="ACL8CG_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1343687.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            19955..20980
                     /gene="trpS"
                     /locus_tag="ACL8CG_001086"
     CDS             19955..20980
                     /gene="trpS"
                     /locus_tag="ACL8CG_001086"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGS1343688.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFTKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            21132..22610
                     /gene="guaB"
                     /locus_tag="ACL8CG_001087"
     CDS             21132..22610
                     /gene="guaB"
                     /locus_tag="ACL8CG_001087"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGS1343689.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(22661..23758)
                     /gene="recF"
                     /locus_tag="ACL8CG_001088"
     CDS             complement(22661..23758)
                     /gene="recF"
                     /locus_tag="ACL8CG_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGS1343690.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNRN"
     gene            complement(23761..24129)
                     /locus_tag="ACL8CG_001089"
     CDS             complement(23761..24129)
                     /locus_tag="ACL8CG_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGS1343691.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SCRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            24288..25538
                     /locus_tag="ACL8CG_001090"
     CDS             24288..25538
                     /locus_tag="ACL8CG_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS1343692.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNELT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSEFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGISSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            25535..26818
                     /locus_tag="ACL8CG_001091"
     CDS             25535..26818
                     /locus_tag="ACL8CG_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS1343693.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            26860..27681
                     /gene="rodZ"
                     /locus_tag="ACL8CG_001092"
     CDS             26860..27681
                     /gene="rodZ"
                     /locus_tag="ACL8CG_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGS1343694.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            27692..28237
                     /gene="pgsA"
                     /locus_tag="ACL8CG_001093"
     CDS             27692..28237
                     /gene="pgsA"
                     /locus_tag="ACL8CG_001093"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGS1343695.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            28234..29061
                     /locus_tag="ACL8CG_001094"
     CDS             28234..29061
                     /locus_tag="ACL8CG_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGS1343696.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPGELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            29046..29885
                     /locus_tag="ACL8CG_001095"
     CDS             29046..29885
                     /locus_tag="ACL8CG_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGS1343697.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            29878..30672
                     /locus_tag="ACL8CG_001096"
     CDS             29878..30672
                     /locus_tag="ACL8CG_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1343698.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            30731..31549
                     /gene="mreC"
                     /locus_tag="ACL8CG_001097"
     CDS             30731..31549
                     /gene="mreC"
                     /locus_tag="ACL8CG_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGS1343699.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            31549..32043
                     /gene="mreD"
                     /locus_tag="ACL8CG_001098"
     CDS             31549..32043
                     /gene="mreD"
                     /locus_tag="ACL8CG_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGS1343700.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            32137..33315
                     /gene="pcsB"
                     /locus_tag="ACL8CG_001099"
     CDS             32137..33315
                     /gene="pcsB"
                     /locus_tag="ACL8CG_001099"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGS1343701.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            33539..34318
                     /gene="rpsB"
                     /locus_tag="ACL8CG_001100"
     CDS             33539..34318
                     /gene="rpsB"
                     /locus_tag="ACL8CG_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGS1343702.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            34397..35437
                     /gene="tsf"
                     /locus_tag="ACL8CG_001101"
     CDS             34397..35437
                     /gene="tsf"
                     /locus_tag="ACL8CG_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGS1343703.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            35792..36007
                     /gene="tnpB"
                     /locus_tag="ACL8CG_001102"
     CDS             35792..36007
                     /gene="tnpB"
                     /locus_tag="ACL8CG_001102"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS1343704.1"
                     /translation="MDSFSGQVFLFCGERKDRFKALYWDGQGFWLLYKRFENGKLTWL
                     STEKDVKALAPEQVDWLMKGFSITPQI"
BASE COUNT        11625 a         5818 c         7254 g        11515 t
ORIGIN      
        1 aaaatccgtc tgatttaatg agtatcacta gtggcgacac tgttctagtc aatccaaaag
       61 gacgcccagc ctttgaagct actttcaagc tattcaatat cttttcaggg aattatattc
      121 ccaatggtgg caacaagaca aaaggctggt atcgtagaat tatgatcgtc ccttttaatg
      181 ctgactttaa cggggagaag gaaaaacctt ggattaaaaa tgagttttta gcaaacaagg
      241 aagtcctaga gtatgccctc tacaaagcta tcaatcaaga gccatttact cactttatcg
      301 aacctaaagc agttaaagga ctcctagaag aataccagga ggataatgac tacttacttt
      361 catgggttaa gcatgaatac atggaaaaag gttggcatga gctggacgta gtacctgttt
      421 ttatcgttac aagatcacta aagcactatg ccgaagatat gggaataccc aaacccaatg
      481 tttacggggc tggtaaagaa actatcaagc acttacaaca gttgacacct aatcggtatt
      541 ctctaagaaa gaaaagagtt ccttcagaag attttgaaaa actagaggca tgggacgttg
      601 acaagataaa aatgcggaca cctcaacact ctatcactaa acaagaataa gtgtgacgtt
      661 ctttttttgc ttaaaccctt gataatactg attttcttaa aaaaagtgtg acgttctcaa
      721 aaaagaaggt tacacccctt gaagccttga tatatctagc tttaggggaa taggtgtgac
      781 gttgtgacat tctttccaac tcttatatat agagaaaaat gcagtattta tatataggaa
      841 cgataaaaca aaagaacgtc acagggtcac aggggtggtg aaacacctag agcctcaagg
      901 gtttgaacgt gtgacgttct ttgtcacaga aggtcacaga acacgaaaaa tattacataa
      961 tttaccttaa aataaagaaa tgacaacaac atgaaagtta aactatttga atatactaga
     1021 cgatgggaaa aagaagactt tgagaaagag atcaatgact tcatggcaac tgttgaagtg
     1081 ctggacgtta aattttctgg tacaccatct agtgaatcct ttaattcggt ggctatcgta
     1141 ttggtattat acagataaca aaatggggta gatagtaccg acccccttgt aatggtgtaa
     1201 ctactagtga cacctttaaa acagaaagag gaaaaacaac atgacattaa aaacattttc
     1261 ggataaagcc aaaacattta ctttcactta cgaatttaaa gacctagata ctgctatggt
     1321 agcaggtcac gcgctactgg gatatatgac tgggacttat gaagtaccat ctatttcaat
     1381 aactcacaag gataaaggga cgcttgtcgc tgagtatgtg gaagatcaca agctaaacaa
     1441 gactttcaag cgtatttgtg acagtttcaa agactattac aaccaaccag tggacgatga
     1501 agcatttgaa gaacgttata aacgggagcg cgtgctccaa ctcaaagagt aagaggactt
     1561 tgagaacttg ctggaaaaag taacagacta cgagctggaa ctattagact atgctgatcg
     1621 cttgctttct gataagccta tccctatgga ctctatgacc gcttttggta cgttggaaat
     1681 gctgggcgat gaaagtatta gcctactcca aaagttggac gtagagggcg aatataaagg
     1741 ccttgctggt tatacagagc atttgaagta gaacacaggg gagcaatccc ctttttgtta
     1801 tcaagtcaat agttttgggt ttttccatat agggggaaat aatgaagcgg ttagcaatag
     1861 aaacaatcac taaaccaatg aagctgagag gaatatctaa gggtatagct gagttggacg
     1921 gtcaacgttt agagattgat ttggataatt taatgattga ttttggtgga gagtcatttg
     1981 aattagacag aatagcagga actaagggag gtaatagata tttctttgcc ctgattgtgg
     2041 gagacggtgc aggttgcttt ataaacggta tttatatttt agttgcggta cttgtctaga
     2101 tatccacaag aacaccctga accgtagtaa aacggattgc caatactact gggagcttgc
     2161 actaaaagaa gccagaaagg tagaaccagg gtggagtcct agacgtggtg gatatatgtt
     2221 tgatagtttc cctgaaagac caaagtatat gaagcgtgac aggtatcata agcactataa
     2281 gaagtttttg aagtatattg aaaaaggaga tagattttgg ctgaatggtt tgagattgta
     2341 ggacaatatg aagtagtgtg caatttacaa aacaaacaaa tactacatat ttgacggttt
     2401 gaatgttaaa aaagctagat atatcaagga tttaagtaag tagagtgttc caaaagaggg
     2461 tgaggtaagg gtgaggttac atataaaaag tacaaggtta gtacaaggtc acatacttca
     2521 aaatagcaag gttttagcaa ggtacagggc ttttttctag tgatagaacc ctaatattac
     2581 cctaaggtat agctactttt ttagaaccat agaacggtaa ggttacggta aggtatcgaa
     2641 gttttccaat ggtgaggtaa gggtgaggta agagcaaaaa atgtaaaggt tttgtcaagg
     2701 ttgcgtattt aaaagcccca aggttaccac aaggtagaga ggtttaccga gggttagaaa
     2761 aggtgagatt ttgcttaggt agtggcagta aatatgcctg gaaaatggca gggttatgtg
     2821 tgttgaactc cgagcgaacg ccgagaaagt ggctatatct ccctccccac gcacttctat
     2881 gagcttcaca ccgtcattgt acattttttc tcacggggaa gcatttgaag ctagagcgaa
     2941 catagagaaa acgaaaaaag ccaagacact ctctgtctca gctaatagtt ctcacaaaga
     3001 ctattatatc atagaggagg ccgaggcatg acaccagagc aggtaaaaga aaaactagag
     3061 ggcgttaagt ggataaacaa agagatagaa ggcttatatt tagagcttgc agctttagaa
     3121 agtggtatta tcaaaaagca agaactaagc aataccagag tacaaacaag cagggtaaat
     3181 acgaccgaga ataaccctat aagtgttcta aaactaaaag aggatacact tcagagaatt
     3241 gagcgactta atgaagagag aatggaaata tctaggctaa tcgataagct agccaatccg
     3301 cttgaacgtt ctgttctcag gctgttctac ttgaatgttc ttgacgcttg gcaagttgct
     3361 gaggaaatag ataaatcaaa gactgcagta tacattataa ggcaaaaagc catagaacac
     3421 ttagcaaatg tggggtaata ggtgagcaca aaaaaacgcc tagaacaatc taagcgctaa
     3481 agagtagtgg acggtgtgcc tgtcccgtca tctcatacta tgaagttgcg tagcgacact
     3541 atcatctcta cctcacttct ctttagacta ttataccaca aaggagcgaa ctaatggagc
     3601 tggataagtt taaaacgatg atgaacgtca gagagcggat gacctacttt ctacgtttcc
     3661 agaggatggc aggaagtgaa aaccaagtta cgatagatga agaggcttgg aaacttgtct
     3721 taccttatcg gtgggatttg agcggtgagc atgaaaaagc aatccgtgag gggttggaaa
     3781 tattcgccca agacatcaac agtatagaaa acaaacgagc tagaaaatac tttattatcc
     3841 attactgtta catgagaaag aaaacaatga gcgaatgcgt agaaatggca gctactagct
     3901 ccactagcta ccaccgatat aaacaaatag ccgtcttaaa ttttgcgaga atccaccaga
     3961 acggagagct agaagtgtat aagtaggcgt ttgtggtgtt ttgttgagaa atgttgagat
     4021 ttaagtgagg ggggatgaca tgattgaaga ttttttgatt gatttggaga atatccaatt
     4081 agaggatatg gagatagatt ttaacatgga tatagacatc gatttaaaca tagattttga
     4141 aatagatgtt gaccttgatg atttagattt aaccttacta caagaattag aagcgtaaat
     4201 gttggcaaat gtaggctgag gcttcatatt cgtcccctat tttgctttgg tttggactgg
     4261 acaattaaaa caccatggat aaactagaag ccctcagaaa cgagtctagg ggcttttgtg
     4321 aggtcataat cttataaacc acgcgcttca tggtataata tacctatcag caaccagcaa
     4381 taaaaaaagc acgtttaacc gtgctagttt cttgcctgct gaactcgtca tttattgccc
     4441 ttttgtgggg ctttttttgt ggactttttg agaattttta agaactttta atgatttcta
     4501 atcaaatgag atttttcaaa aagtcagtaa tatcaagggt ttaggcgctt taaacaagtt
     4561 taaaagcgta tagattacaa tctaacacaa aaagggataa agtgctaacc ctctaactaa
     4621 gggttctcag tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac
     4681 aacatgctca caattactgc attttatttt gatatctgct cctacacgtg taatttccca
     4741 acaattagcc tttttaccag tcgacttgat tgtacaagcg tgtgattttt tcatctcaac
     4801 aaaatttcca acttgataca tactactctc cttttctttt tcgattatat cataaaagag
     4861 gcgagccagg ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga
     4921 agtcttcgtc agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa
     4981 tggtcacctt ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac
     5041 taatggtcaa atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa
     5101 cttctggaga gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac
     5161 cattttgagt cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca
     5221 cattaaaagt aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt
     5281 ttccttctag gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat
     5341 tggcaaagaa aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta
     5401 gagaacggct aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt
     5461 tctggcttag gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata
     5521 cgaagtggac acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt
     5581 cattaataat tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt
     5641 cttggattcg tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac
     5701 tggttaaaac aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac
     5761 tagatactac attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatta
     5821 acaaaccagc atcttcattt ttttgagaaa taaaattttc aattgaaatt tgaccatttg
     5881 aaccaattaa agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa
     5941 tggcattttt agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt
     6001 tattaattga aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa
     6061 tagtaataat agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt catatcaagt
     6121 tttttagctt gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa
     6181 ttatttgatt ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat
     6241 caaagatttt attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc
     6301 cttcccaatt tttggaagac tattatctgt tagttctcta gataaataca tggctacttg
     6361 acgggccaaa acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc
     6421 ataaaagtta ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac
     6481 atcttgtttg cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt
     6541 ttttactctg gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga
     6601 atcaaattgc ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc
     6661 cgttttactt tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt
     6721 caatccccaa ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact
     6781 acgatcactc gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa
     6841 aaattcttcc tgagttgcga ctttttttcc gctgagtgac tggatatcat cgattaacaa
     6901 aagatcaaga ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc
     6961 aagaaagtca ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt
     7021 ttttagaatt tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc
     7081 atagataaaa agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga
     7141 cacagcccaa acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa
     7201 tcccgtatct gaataaggaa tagatactaa ctttggacta tagttataaa gagttaaatt
     7261 tgtagcttct tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg
     7321 agttatttca gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt
     7381 ttcccagacc atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac
     7441 cttgatgagt tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg
     7501 tgcaaattct aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac
     7561 tatttaaaag tttaatacta gagatatttt accatagata gcaagaattt tccacaagct
     7621 gtgaaaaata atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa
     7681 ttattgattt attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa
     7741 ataaaagaac agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa
     7801 aaagaaataa tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg
     7861 agtagttttc ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc
     7921 ttttgttttt tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata
     7981 atccgttgaa agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg
     8041 gcttgtgata gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa
     8101 cgaatggagt tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg
     8161 gtgaatcctt tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt
     8221 tctctctgta aattttcaat aatggactgg accatcatct cttggtctga aatctgttta
     8281 acaacagctg ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct
     8341 gcaaggattt cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca
     8401 ttttctttga tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt
     8461 tgatagggat ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta
     8521 cactaacaca tcttttctct tatgtaaagc tttctttaca tagatgtcaa ttaagattct
     8581 aaatcacctg aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag
     8641 taggttatct taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt
     8701 gatgaagcaa tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca
     8761 ttggcaggca tattactttg taccgaacga acaactacac cagatgtaac attacttgga
     8821 atattgagtc ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc
     8881 aaagctggac gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca
     8941 tttgcaggaa ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta
     9001 cttgaggtaa ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct
     9061 gggttaatag cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat
     9121 tttaaggata catttctatt gagactggat acgatacctt gagtgacagt atttgcatat
     9181 tcagaaccta acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa
     9241 tcaccaaact cagctactgt tgtcactttt tctgaagaga tttttacgac agcaatatca
     9301 gagaaagtgt cagctccgac aatttctcca ggtactttag tcccatctga caatcgaata
     9361 tctactttgc tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca
     9421 ttctttttat aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta
     9481 tcatcattgc caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca
     9541 gcatctttta ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt
     9601 gtaatagtac tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt
     9661 gaaaaactac ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac
     9721 cattttttgt aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga
     9781 aagtataaac tgactagctt aattataact taaacacaaa agttttacac aaactgtgga
     9841 taactctttt gaaactgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga
     9901 tgtgaaaaaa tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg
     9961 gaaactgaaa gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag
    10021 atttgctaag tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga
    10081 atcagaaaat caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga
    10141 ccgtgatttc gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag
    10201 taagcagtta gaagaaactt ctataaaagg attttctact cttactttta ttattggggg
    10261 aagtttagga ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg
    10321 cctaacctta ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt
    10381 tacgattcag cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg
    10441 gtagaataat tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga
    10501 acggtcgcag gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg
    10561 gcttttttct taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc
    10621 taaaacgaaa ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt
    10681 ttaggagatt ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa
    10741 aaagacttac aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt
    10801 attttacaaa gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg
    10861 ggacggttat tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc
    10921 aaataaatag aaaagaatta ttcgttcttg gtgcttatac attactaaca gaaatagtat
    10981 ttgattttcc cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc
    11041 ctttgggatt atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat
    11101 tcctaagttt actactatct cttttatatg agagcactca taactttctg tccgtaactt
    11161 tctcctctat aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg
    11221 tgacggtgtt aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag
    11281 cctattttga cgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat
    11341 tgctacatat tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt
    11401 ttggaagtat tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga
    11461 attctcataa agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga
    11521 aacatttaca gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc
    11581 gacatgatta tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac
    11641 aggaaattga cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag
    11701 ataagtacac ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg
    11761 ctcagtcaat tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata
    11821 cgattaccaa gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga
    11881 ataatgctgt cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta
    11941 agatggaaac tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt
    12001 caggagatct atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa
    12061 ataatgtgaa agaactacta gataagtaca acaatattat tttagaaaca gagatggaag
    12121 gcagtacatt tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt
    12181 agaagatgtt attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga
    12241 atcgaatatt ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat
    12301 tgaaaatgat gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa
    12361 aaagggattt gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt
    12421 tatcactagt cgatcagagt ttgcgactct aacctataaa taccaggtat cagccctaga
    12481 ttttgttgat aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt
    12541 ctacacgaag agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta
    12601 caaaggaaat gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt
    12661 ctctcataaa ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac
    12721 agatattcag gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt
    12781 ggtaaatata ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga
    12841 agaccatcgt tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa
    12901 aaaatctcaa aagtgattga caattagcaa gaaattgata taatggttat atctgctaca
    12961 gatagaaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt
    13021 tcgaatcccg tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt
    13081 taatcatgat gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc
    13141 tgtgttcctc tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat
    13201 ttcttgagaa ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc
    13261 atgagttaga tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa
    13321 tcgcttttgt aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat
    13381 ttctttagtc ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc
    13441 aaaaacttct aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa
    13501 tgtatggaat agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt
    13561 atagaagctg gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc
    13621 aaatggctgt tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa
    13681 gcgtttgtta ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa
    13741 atagattttt tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt
    13801 agacaatatg tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa
    13861 accaaccttt attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat
    13921 atttttgtca tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt
    13981 aaataatgat aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt
    14041 gtccaattta aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa
    14101 gaagggattg gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga
    14161 aaaaacaact acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga
    14221 gcaacaaact gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc
    14281 tcagtcaatt gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca
    14341 atcttctaat ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac
    14401 ttctttgata ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt
    14461 agttcctgcc agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa
    14521 agtttctcag ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgaa
    14581 taaactagtt tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt
    14641 tggttaatta caatcaggat ctgggtaatt agcagacaaa tccagtcagt tactttcagg
    14701 tgcttctcca ttagagaata gagctaataa attggcagat ggatctggga aactagcaga
    14761 aggtggaaca aagttaactt ctggattgga agatttacag acaggacttg cttctttagg
    14821 acaaggacta ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc
    14881 agagattttg tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcttgtaaa
    14941 tggaatcgca atagctcctt atatgatatc agttgctctt tttgttgcag caatatcaac
    15001 aaatatgata tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt
    15061 gaaatctcga gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg
    15121 aggagttcag cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat
    15181 cctaacaagt ttagtattca tgtctatggt gaccacttta acaacgtgga atagccgtat
    15241 aggagctttt ttctcactta ttttgctttt actacagtta gcatcaagtg caggtactta
    15301 tccacttgct ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta
    15361 ttcagtttcg ggattacgac aaacaatctc catcaacaag tcattttcct agctgtcata
    15421 ctagctctat ttactggttt aggtatgcta gcctatcaac ataagaaaat agaagaagat
    15481 taaaaaaatc gaccgattaa ctggtcgatt ttttatgcct tagatgactt tcgtctgtga
    15541 ttatagattc caaatagtaa gagagaagta aaggaacaga ttgctccagt aataaaacca
    15601 ttgggaatga aggaaagtgt aatagttcct ttccccttgg gaatgtcaac tttcataaat
    15661 ccagtttgag cttgtttaat ttctattttc ttaccatctt ggtaggcaga ccaacctttg
    15721 tcataaggaa tggtgaagaa aatagatgta tcttgttgga catcatatgt agcaaaaacc
    15781 ttgtttttag aagttgatac tgtgacaggt tgttctttaa ttttttgaat tgcctcggtg
    15841 aaagttttgg tatctaaacg atagaaggta ggagattcaa atgatacttg tgaatttcca
    15901 gggaaactaa cattgatatt gaaagttttt ttctctttag tatatcctag attaaagaag
    15961 gagaagacat tatcagttgt aaaagtcttt ttttcaccat ttacaaggat gtcaaccttc
    16021 ttttgtttat cgttagaaaa gtgaaggttt atgaaagaga gataaacttg gctgttttct
    16081 ggaacttcaa tttgatactg gattgctgca tcttcatttg aagaacttgt gacactaatc
    16141 aaatcattag tattttctat tttttctgtt ttttcataag gtattggaga aaaataatca
    16201 aaattgacgt tagcaagttg atttaaaaat gaggcctgat tatccaaggt atgttcattg
    16261 aacttgacat cattgtaaac agattgacta gcaactgcaa tcggaagaga gtattgattt
    16321 tcatataggg taagattatc tttttgatag atatctttaa agccatactt atcaatagga
    16381 ctgtctgaga tattgtactg gataccaaat aaactatcag ccaaaatact attatttgca
    16441 tatcggagat tgagattagt cccagaggat ttaaaaccaa gtttatctaa agtagagctt
    16501 gatgaacgat ttcgaacaga tgaaaattga gagattccat tgtagttgaa tttcatactg
    16561 tcatttcctg tctgagtttg tagtttttca gtacgagtaa attgatttcc aatatatgtt
    16621 gagaaagatt ccatagctgg gatatctcga ctataagcac ttcgagaagc aaatccccat
    16681 tccttagcaa ttccgtccat ttgagatgaa gcatttaaac tcatttcaac cagtataaat
    16741 aaagagatta gaatggcaaa tagattcaca gatataaact ttttgataac tgcaaggagt
    16801 aaaagagaat agacaaccaa aaattcaaga gtaagcagaa tattcaaatc tgttaaaaaa
    16861 gaataatgcg attttagata gatggtagct aaaaatcctg ttactacaag aaaaagcgaa
    16921 actaaaaaat tccagacttt aagttctttc agacgcttta agacttctgc tgctgtgtaa
    16981 attaacaagg tagagaaaat ccaagcatag cgatgtaaaa acatgtttgg agtatgcatg
    17041 ccttgccaaa ataagtcaag agcttctatg taaaagcttg caattagaaa tgcaaagaat
    17101 attatatata tgagtttcac gtgaaaccta atagatttca gcgtaaaaaa taaaatggtc
    17161 aaaataaagg gaagtagtcc aacaaaaatc attgggatgg ccccatactt tgttgtgtca
    17221 aaggaaccaa tgaattgctt agcaaagaga tcaagatacc agctactttc agtttgaaac
    17281 tttgtaactt cagtcaattt ttccccatgt gtctgtaaat caaacagagt gggaagagtc
    17341 ataatcaaac tagccatacc agctaaaaag gagataacta tgaaatcaag aacagatgat
    17401 tttcgagtct taaagtccca cgaaatttga cagagatacc agaaaataag aaacaatact
    17461 gtcatatatc caaaataata attttgaata aataagattg acagacttgt aaagtacaat
    17521 aggagtttct tttcagttat cagtagatgt aaaccagtta taattaaagg aatcaagata
    17581 aaaacatcta gccaggtttt tatctctaat tgactgacag tgaaacccat cagagcatag
    17641 gaagtagata aggctagttt taaagtctga gggatagatt gaaacaattt attcaaacta
    17701 aaaaaggttg acagaccaat caatccaaat tttaagagag tggtcagata gacagcatct
    17761 ggcatattcg ttagatcaaa aaagtaaact agaggcgcga gaaaactacc caagtaataa
    17821 ctagataggg catagaagtt tagccctaga ccacttgtaa aggtgtaaaa cagactacta
    17881 tttccatgta ggatatttcg taaggctaca tcaaaaataa cgtattgatg aaagccatct
    17941 cctaatagag gagagttgtc gctattccag tagatacctt gagatagata tactccagac
    18001 ataatcacta caggaatgat gaaagaaata aaataggttc gatatgtttt taaaaatgat
    18061 ttcatgttac ctcgtagaat gatagaaaac tcagttggtt aacccaactg agttttgaag
    18121 ttttatttag tctttccaaa gttctttaac ttttgcttgt acttctgcat tttctaggaa
    18181 ttcatcgtag gtttcatcga tacggtcaat gacgccattt ttagataaga caatgatatg
    18241 gttagccaaa gtttgaataa attcgtggtc atgactagca aagatgattg attctttaaa
    18301 gtttttcaat ccatcattca agcttgagat agattccaag tccaagtgat ttgttggatc
    18361 atcaagtaca aggacatttg attttaagag catgagtttt gaaagcatga cacgaacttt
    18421 ttctccccct gacaagacat ttacaggttt gttaacttca tctccagaga agagcatacg
    18481 gccgaggaaa ccacgtagga aagtattgtc atcttcttct ttacttgcga attgacgcaa
    18541 ccagtcaaga attgattctc ctcctgcaaa atcagctgag ttatcttttg gtaggtaaga
    18601 ttgactagtt gtaactcccc acttgacagt tccttcatag tcaatatctc ccatgattgc
    18661 acgaattaat gcagtcgttt gaatatcatt ttgtccaata agtgctgtct tatcatctgg
    18721 acgcaagatg aaactaatat tatccaagat agtttcacca tcaatcttta cagttagatt
    18781 ttctactgtc aagagatcat taccaatctc acgttccgct ttaaagttga taaatggata
    18841 tttacgacta gatggtacaa tctcttctag ctcaatctta tcaagcattt tcttacgtga
    18901 tgttgcctgc cttgacttag aagcattggc agagaaacga gcaacgaatt cttgcaattg
    18961 tttaattttt tcttctgctt tagcattacg gtctgctagc aatttagcag caagctcaga
    19021 agattccttc cagaagtcgt agtttccgac atagagtttg atttttccaa agtcaaggtc
    19081 ggccatgtga gtacaaactt tgtttaagaa gtgacggtcg tgggatacta cgataactgt
    19141 gttatcaaag tcaattaaga agtcttctaa ccaagtaatc gattggatat ccaaaccgtt
    19201 agtaggctcg tccaagagaa gaacatctgg tttaccaaaa agtgctttgg cgaggagaac
    19261 ctttactttt tcaccgttgg ccaattcgct catgttttgg tagtgtaatt cttctggaat
    19321 gtttaggttt tgaagtagtt gagaggcttc actctctgct tcccaacctc caagttcggc
    19381 aaactctcct tcgagttcgg cagcacgaac cccgtcctcg tctgagaaat cttccttcat
    19441 gtagatagca tctttctctt tcatgatgct ataaagtttt tcatttccca tgataacgac
    19501 atcaatggca cgttcatctt cgtagtcaaa gtgattttga cgaagaacag agagacgttc
    19561 atctggacca agagagatgt gaccagtagt aggttcgata tctccagcta aaatttttaa
    19621 aaaggttgat tttccggcac cattagcacc gattaatccg taagtatttc cttctgtaaa
    19681 tttgatattg acatcatcaa aaagtttgcg atcactaaaa cgtagtgaaa catcagatac
    19741 tgtaagcaat atttttctcc tatatgtgta atatatttat tctactagaa aatacagaaa
    19801 tattcaaatt tttatttatc aattttgtgt aaattatatt tacagtatcc tttacacaaa
    19861 tctgtaaaaa gcaaggctga tttattttga taaattacgg ttatttcatt aaaaaaatgc
    19921 tataattgaa aggactatat cgaaggagaa caaaatgact aaacccatta ttttaacagg
    19981 agaccgtcca acaggaaaat tgcatattgg acattatgtt ggaagtctca aaaatcgagt
    20041 attattacag gaagaggata agtatgatat gtttgtgttc ttggctgacc aacaagcctt
    20101 gacagatcat gccaaagatc ctcaaaccat tgtagagtct atcggaaatg tggctttgga
    20161 ttatcttgca gttggattgg atccaaataa gtcaactatt tttattcaaa gccagattcc
    20221 agagttggct gagttgtcta tgtattatat gaatctagtt tcgttagcac gtttggagcg
    20281 aaatccaaca gtcaagacag agatttctca gaaaggattt ggagaaagca ttccgacagg
    20341 attcttggtc tatccaatcg ctcaagcagc tgatatcaca gctttcaagg ctaattatgt
    20401 tcctgttggg acagatcaga aaccaatgat tgagcaaact cgtgaaattg ttcgttcttt
    20461 taacaatgca tataactgtg atgtcttggt agagccggaa ggtatttatc cagaaaatga
    20521 gagagcaggg cgtttgcctg gtttagatgg aaatgctaaa atgtctaaat cactaaataa
    20581 tggtatttat ttagctgatg atgcggatac tttgcgtaaa aaagtaatga gtatgtatac
    20641 agatccagat catatccgcg ttgaggatcc aggtaagatt gagggaaata tggttttcca
    20701 ttatctagat gtttttggtc gtccagaaga tgctcaagaa attgctgata tgaaagaacg
    20761 ttatcaacga ggtggtcttg gtgatgtgaa gaccaagcgt tatctacttg aaatattaga
    20821 acgtgaactg ggtcctattc gtgagcgccg tattgaattt actaaggata tgggagaagt
    20881 ttataatatg attcaaaaag gtagtgaaag agcgcgtgaa gttgcgggtc aaaccctatc
    20941 tgaggtaaaa ggggcaatgg gacttcatta ctttaactaa gtttatttta caagaaacta
    21001 tcttttctat ctcgaagaaa agatagtttt ttatttaccc ctgtaacatt tgacaaattt
    21061 ttatagaatg gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga
    21121 ggaaacttcg aatgtctaat tgggacacta aatttttgaa aaaaggtttt acctttgatg
    21181 atgtattgct tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta
    21241 aattggcaga taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta
    21301 cagagagtca aatggccatt gctattgctc gtgcaggcgg tctcggagtt atccataaaa
    21361 acatgtcaat tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag
    21421 ttattattga tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta
    21481 tgggtcgtta ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg
    21541 ttggtatttt gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa
    21601 accatatgac tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg
    21661 agagtattct tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc
    21721 tttctggttt gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta
    21781 aagatgagtt tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg
    21841 aacgtgcaga ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg
    21901 gtcattctgc aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga
    21961 ctttgattgc tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg
    22021 tagacgttgt taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg
    22081 gtgttggtgt tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg
    22141 gtaaaacgat tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg
    22201 ctgcaggtgg aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag
    22261 gcgaaactga aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg
    22321 ctgctatgaa gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca
    22381 agcttgttcc agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg
    22441 ttttccaaat gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta
    22501 aagaactaca cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc
    22561 atcctcatga tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga
    22621 aaagaactcc agtgaaaaca ggagttcttt tacaatgttg tcaatttcta tttacagcag
    22681 ctttaccatc ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta
    22741 agcttgttgt tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact
    22801 gtctagtgtt gtcaagttca ctcatcacat cgtcaagcag taatatcgga gattctgtgg
    22861 taatgctttc cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt
    22921 gaccttggct tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat
    22981 gaggaccgac accagtattc tttttaaata aatctctgga tctacttttt tctaaagcaa
    23041 ttttgaaaga ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata
    23101 ttgacaactc ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta
    23161 gtttttttat gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat
    23221 catctaacac agaaaggaat gtttcatcta ttttttgagc tgattttagg taagtgtttc
    23281 tttgctttag gatgtggtta taattggtta agtcagataa atagattggc ttaatttgcc
    23341 caagttccat atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat
    23401 cttcaggagc aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt
    23461 ttaagtgatt aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg
    23521 atccagtttt tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga
    23581 gatttttatc tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta
    23641 acatgtttgt ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt
    23701 ctattttcgt ttctttgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga
    23761 ttatctacca gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt
    23821 gtctttttta actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac
    23881 tttatcagct tggtattcat cttgttcttc agaagtaggt tgtgtcaaca agatgtcaat
    23941 gttcatgtca gggatgtcaa ctttatcgcc aatacgaagt ttttttccac gacaactctc
    24001 taattcccta ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct
    24061 atgtgtaatt ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt
    24121 gtattccata attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga
    24181 gagacagcga gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa caagaaaatt
    24241 tcaggttttc gtgatataat agaagtctgt atataaggag gtaaatcatg gagttagtgc
    24301 atggaatttc aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc
    24361 gttttaccgc tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc
    24421 tagagactgc taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc
    24481 tatacggtac agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat
    24541 tgacatttac ctatgttcgt gatgagtttt taagtaggaa aaacgagcta acctctcaga
    24601 ttttggaact tgtaaaagaa actctttttt cacccgtagt agttgataat gggtttgatc
    24661 cggccttatt tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg
    24721 attcttttta ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc
    24781 aattggaata tagtgattta cgaaatcgta ttttagctga aactccacaa agttcttatt
    24841 cttgtttcca agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta
    24901 atgaggttga aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg
    24961 tgaaggttca gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa
    25021 atgtgggaca atccattttg gaattaggtt atcattaccg ttctaaatat ggtgatgagc
    25081 aacatttacc catgattgta atgaatggtt tacttggtgg atttgctcac tctaagctct
    25141 ttacaaatgt ccgtgaaaat gctggattag cttataccat ttcaagtgag cttgatttat
    25201 ttagtgaatt cttgaggatg tatgctggta tcaatcgaga aaatcgtaac caggctcgta
    25261 aaatgatgaa taatcaactg cttgatttaa aaaaaggtta ttttacagag tttgagttaa
    25321 atcagaccaa ggaaatgatt cgttggtcgt tgttactttc tcaagataat caatcttcat
    25381 tgattgaacg tgcttatcaa aatgccttat ttggaatatc ttcagcagac tttaaaggtt
    25441 ggattgcaaa actcgagcaa gttgacaaag atgctatttg tagagcagct aataatgtga
    25501 aactacaagc gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa
    25561 atactatcca gctgtaaaag aaaaggttta tcgaactcgt ttggccaatg gattgacagt
    25621 tgctcttttg cctaaaaagg aatttaaaga ggtttacggg agtgtcactg tacagtttgg
    25681 ttcggtagat acgtttgtca cagaagttga cggagatgta aaacaatatc ctggaggaat
    25741 tgctcatttt cttgaacata aattatttga gagagaagat tctagtgatt tgatgtcggc
    25801 ttttacgagt ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct
    25861 tttttcagca acggattatt ttttagaaaa tttagattta cttgatgaat tggtaacatc
    25921 agcacacttt actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga
    25981 aatgtaccaa gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc
    26041 tggtacacct ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct
    26101 aactaatttg caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt
    26161 agttggtaat tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga
    26221 ttcagatttt caggaagtag caagagaaaa gttgttttta cagcctgtaa agccaacaga
    26281 tagtatgaga atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga
    26341 agtttctgaa gcggattgct atcgacatca tattttatta aaattattgt ttgcaatgat
    26401 gtttggttgg acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcatc
    26461 cttatctctg gaagttgaag taacaagtcg ctttcatttt gtcatgttga caatggatac
    26521 gaaagagcca gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga
    26581 tttagatatt acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt
    26641 cagtagcatg aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga
    26701 gacaattttt gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc
    26761 tggacatcat ttaatagatg atggtgacat agttgatttt acaatattcc catcgtagta
    26821 acctattata atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga
    26881 gaggttttac gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag
    26941 acagaaatcc agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca
    27001 agtccttttt acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac
    27061 caaattgttt tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt
    27121 gatgaagatg agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaacatca
    27181 tttttacctt tattttattt tatccttttt gctttatcga ttttaatttt tgtgacttat
    27241 tatgtttgga actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg
    27301 gttcaatcaa caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt
    27361 atagaatcag ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca
    27421 agtaaggaaa cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt
    27481 tcagaaagcg aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca
    27541 acagttgcaa ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg
    27601 acagtagata atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact
    27661 gtaaccttta ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt
    27721 aacaataggt cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc
    27781 gatagagagt catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt
    27841 agatggatat ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc
    27901 tatggcggat aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc
    27961 tccggcttgg attgttgcag tgattatctg tcgtgagtta gctgtgacag gtttaaggct
    28021 tttattggtt gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac
    28081 ttttagtcag atgtttgcta ttattttctt gctattacat tggactttgc ttggtcaagt
    28141 tctactttat gtagccttat ttttcactat ctactctggc tatgactatt tcaagggtag
    28201 tgcctatgta tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat
    28261 ctttcttttc gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac
    28321 gtgaaacgtg gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg
    28381 gttcgattaa ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa
    28441 cgtttgactg aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat
    28501 ccagacaatc aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat
    28561 cagggacttt ctcgtcaaga aatgaaaaag agagtggaag aagctctggc tttagttggc
    28621 atgttggact ttaaaaagag agagccagcg cgtctatcag gtggccaaaa gcaacgtgtg
    28681 gccattgcag gtgttgtagc cctaagacca gctattttaa tcttagatga agcaacgagt
    28741 atgttggatc ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac
    28801 tatgatatga cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc
    28861 gtattggtca tgaaaaaagg ggaaattgaa tcaactagta gtccagggga gcttttctct
    28921 cgaaatgatt tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct
    28981 ttgagccaga atggctatga tttacctgaa aattatttga cagaaagtga gctagaggat
    29041 aagctatggg aattgctcta gaaaatgtga attttacata tcaagaaggt actcccttag
    29101 cttcagcagc tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa
    29161 ttgggcacac aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc
    29221 caagtcaagg gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag
    29281 atattcgtca aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt
    29341 ttgaagaaac ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag
    29401 aagatgctgt gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt
    29461 ttgatcgtag tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca
    29521 tacttgccat ggagccagct atattagtct tagatgagcc aacagctggt ctagatcctc
    29581 tagggagaaa agagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg
    29641 tcttggtaac gcatttgatg gatgatgttg ctgaatatgc aaatcaagtc tatgtaatgg
    29701 aaaagggacg tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta
    29761 tggaagaagt tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata
    29821 gaggcgtgtc atttaaacga ttaccgatta agatagagga gtttaaggag tcgctaaatg
    29881 gatagtatga ttttggggcg ttatatccca ggggattcga ttgttcaccg attggatcca
    29941 cgtagcaaat tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc
    30001 ttgacgaatc tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct
    30061 ctttcatttt ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt
    30121 tttcaactat ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc
    30181 acggattatg ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc
    30241 ttttcaactt tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct
    30301 ttattagcac ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct
    30361 atgagtttgc gttttgtccc aaccttgatg gatgatacga cgcggattat gaatgcacag
    30421 aaagctcgtg gagtggattt tggagaagga agtatcgttc aaaaagtaaa ggcgatgatt
    30481 cccattttga ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct
    30541 atggaagcgc gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg
    30601 actctaaagg atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc
    30661 ttaaaatctt agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa
    30721 aggtagggat atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt
    30781 tctgcttgtg tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg
    30841 agatggaatc tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt
    30901 caaatcagat ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca
    30961 gctttaccaa ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca
    31021 actgcgccaa ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga
    31081 tgttattatg cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc
    31141 aaaaggtgct tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc
    31201 aaaagtagag gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa
    31261 gatttctgtt aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga
    31321 caaggaaaat gacgttctta aaattagcca attaaatagt aatagcgata ttagtgcggg
    31381 agataaggtg actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga
    31441 agtggttgcc acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag
    31501 tgcagatact cataatgtag atgtgataga attagtgggg aattcataat gagacagttg
    31561 aagcgagttg gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc
    31621 cagcttctgg gctcattttt cccccatgta catttggcta gtcattttct ttttctattt
    31681 ctcttatttg agacgataga agtatcagag tatctctacc tagtctattg ttttgttata
    31741 ggcttggttt atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc
    31801 ttattgggag ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga
    31861 atgctagcta tgattgtgct gacattcctg tttgaaatgg gtagttatct tttggctttt
    31921 atggtagggt tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg
    31981 atgattttaa attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta
    32041 taagaacgac atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac
    32101 tagtattgtc tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca
    32161 cttttattaa gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa
    32221 acgactgatg acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa
    32281 caagaagccc aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag
    32341 cagtctaact tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt
    32401 gagattacag aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct
    32461 cgtagtgctc aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa
    32521 tcaattacag aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac
    32581 aaaatgttag aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat
    32641 aatgatgcta tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca
    32701 ttgactacga aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg
    32761 acagctgaag gggaaaaagc aagtctatta gagcaaaaag cagcagctga ggcagaggct
    32821 cgtgcagctg cggtagcaga agcagcttat aaagaaaaac gagctagcca acaacaatca
    32881 gtacttgctt cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca
    32941 gcagcacctg tccgtgcaaa agttcgtcca acatacagta caaatgcttc aagttatcca
    33001 attggagaat gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt
    33061 aatggagcac agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct
    33121 caagttggag caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca
    33181 gctgttgaat caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca
    33241 attggaaatc accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat
    33301 atttatgcag attaatttac agagggactc gaatagagcc ctcttttcag gttttaccgt
    33361 gacaatctct attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaga
    33421 atgaaaattg tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct
    33481 tgggtcgttt tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat
    33541 ggcagtaatt tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg
    33601 tcgctggaat cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccacgttat
    33661 cgacttgcaa caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc
    33721 agctaacgat gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc
    33781 tgaagaagca gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct
    33841 tacaaactgg ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga
    33901 agaagatgga actttcgaag ttcttcctaa gaaagaagtt gcacttctta ataaacaacg
    33961 tgcgcgtctt gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat
    34021 gtacgtagtt gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat
    34081 cccagttgta gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc
    34141 agctaacgat gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat
    34201 tatcgaagga cgtcaaggtg aggatgcagt agcagttgag gcagaatttg cagcttcaga
    34261 aactcaagca gattcaattg aagaaatcgt tgaagttgta gaaggtgaca acgcttaatt
    34321 tatacaaata gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa
    34381 atataggaga attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa
    34441 atctggtgcc ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga
    34501 aaaagcgatt gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aagctgaccg
    34561 tgttgctgca gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga
    34621 agtaaacgct gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac
    34681 tacagctaaa gtcattgctg aaggaaaacc tgctaacaac gaagaagctc ttgctttgat
    34741 aatgccttca ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctataggaga
    34801 gaaaatctca ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc
    34861 ataccaacat aacggtggac gtatcggtgt tatttcagtt gttgaagatg gagacgaagc
    34921 acttgctaaa caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa
    34981 agaattggat gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca
    35041 agacaacgaa agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc
    35101 aaaagctcaa ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt
    35161 ggctgcagaa ggcaaaccag aaaaaatctg ggacaaaatt attccaggta aaatggatcg
    35221 cttcatgctt gataacacta aagttgacca agcttacaca cttcttgcac aagtttacat
    35281 catggatgac agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga
    35341 gtttgctcgc tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga
    35401 agttgcagct acaatggcag cagccttgaa taactaataa tagaaaggaa gcaaattgct
    35461 tccttttttg tatagggctt agatttttcc tgaaattgtt ttttccccag tctcactcga
    35521 ttagaataat taaaacaaaa agccctataa taagggctaa gtgcatttag gagactatac
    35581 ttaaaattca tagtaagcgc gttcataaca aggtatctat cctaattccc caacttccag
    35641 tatactagat aaaaaataat tatcggagta aaggtattgt actatgataa ttcaactaag
    35701 tgatttaggt caagttcacc ttgtttgtgg caagacagat atgaggtagg gaatagactc
    35761 attagcctat gtagttaaaa cccactttga attggattct ttctccggtc aagtctttct
    35821 cttttgtggt gaacgtaaag accgctttaa agccctttac tgggatggtc aaggattttg
    35881 gctactatat aaacgctttg agaacggaaa actgacttgg ctaagtacag aaaaggatgt
    35941 caaagctctc gcacctgaac aagtagattg gcttatgaag ggcttttcta tcactcccca
    36001 aatatagtgg atttaaacta gaatagtaca cctctgcttc taaaacattg ttagaaatcg
    36061 atttgactat cctgttctta tttcatttta ctataaattc atcagaaagt cgtgatttct
    36121 attgaaatga ggactttctt tttatactca tctgttttca aaaagcattc tagtccatct
    36181 ccgattaacg atggacttta tcacctcctt ct
//
LOCUS       DBEROT010000019        35228 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.19, whole genome shotgun sequence.
ACCESSION   DBEROT010000019 DBEROT010000000
VERSION     DBEROT010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35228
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.19"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..338
                     /locus_tag="ACL8CG_001103"
     CDS             <1..338
                     /locus_tag="ACL8CG_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1343705.1"
                     /translation="KINVKETSDTANGSLSPSNSGSSVTPMNHNHAPGTTDSVPADTM
                     TSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGL
                     GLKNKKEEN"
     gene            505..1203
                     /locus_tag="ACL8CG_001104"
     CDS             505..1203
                     /locus_tag="ACL8CG_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1343706.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1200..2252
                     /locus_tag="ACL8CG_001105"
     CDS             1200..2252
                     /locus_tag="ACL8CG_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS1343707.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2447..3058
                     /gene="rpsD"
                     /locus_tag="ACL8CG_001106"
     CDS             2447..3058
                     /gene="rpsD"
                     /locus_tag="ACL8CG_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGS1343708.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3236..3391
                     /locus_tag="ACL8CG_001107"
                     /pseudo
     CDS             3236..3391
                     /locus_tag="ACL8CG_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            3817..4077
                     /locus_tag="ACL8CG_001108"
     CDS             3817..4077
                     /locus_tag="ACL8CG_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343709.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            4031..4252
                     /locus_tag="ACL8CG_001109"
     CDS             4031..4252
                     /locus_tag="ACL8CG_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343710.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            4571..5500
                     /locus_tag="ACL8CG_001110"
     CDS             4571..5500
                     /locus_tag="ACL8CG_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1343711.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5514..6437
                     /locus_tag="ACL8CG_001111"
     CDS             5514..6437
                     /locus_tag="ACL8CG_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1343712.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6695..8170
                     /locus_tag="ACL8CG_001112"
     CDS             6695..8170
                     /locus_tag="ACL8CG_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1343713.1"
                     /translation="MKNWKKYAFTSASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8442..9428
                     /locus_tag="ACL8CG_001113"
     CDS             8442..9428
                     /locus_tag="ACL8CG_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGS1343714.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9550..10410
                     /locus_tag="ACL8CG_001114"
     CDS             9550..10410
                     /locus_tag="ACL8CG_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGS1343715.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(10588..11652)
                     /locus_tag="ACL8CG_001115"
     CDS             complement(10588..11652)
                     /locus_tag="ACL8CG_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGS1343716.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11714..12625)
                     /locus_tag="ACL8CG_001116"
     CDS             complement(11714..12625)
                     /locus_tag="ACL8CG_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGS1343717.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12618..13211)
                     /locus_tag="ACL8CG_001117"
     CDS             complement(12618..13211)
                     /locus_tag="ACL8CG_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGS1343718.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            complement(13198..13524)
                     /locus_tag="ACL8CG_001118"
     CDS             complement(13198..13524)
                     /locus_tag="ACL8CG_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS1343719.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13663..14829)
                     /locus_tag="ACL8CG_001119"
     CDS             complement(13663..14829)
                     /locus_tag="ACL8CG_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGS1343720.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            14887..16044
                     /locus_tag="ACL8CG_001120"
     CDS             14887..16044
                     /locus_tag="ACL8CG_001120"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1343721.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIIEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            16086..17936
                     /locus_tag="ACL8CG_001121"
     CDS             16086..17936
                     /locus_tag="ACL8CG_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGS1343722.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQEIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(18022..18192)
                     /locus_tag="ACL8CG_001122"
     CDS             complement(18022..18192)
                     /locus_tag="ACL8CG_001122"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343723.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NIYIRQGDVDVV"
     gene            complement(18242..18874)
                     /locus_tag="ACL8CG_001123"
     CDS             complement(18242..18874)
                     /locus_tag="ACL8CG_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1343724.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18896..19768)
                     /gene="sdaAA"
                     /locus_tag="ACL8CG_001124"
     CDS             complement(18896..19768)
                     /gene="sdaAA"
                     /locus_tag="ACL8CG_001124"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGS1343725.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19777..20448)
                     /gene="sdaAB"
                     /locus_tag="ACL8CG_001125"
     CDS             complement(19777..20448)
                     /gene="sdaAB"
                     /locus_tag="ACL8CG_001125"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGS1343726.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20690..21262
                     /locus_tag="ACL8CG_001126"
     CDS             20690..21262
                     /locus_tag="ACL8CG_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS1343727.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21315..21641)
                     /locus_tag="ACL8CG_001127"
                     /pseudo
     CDS             complement(21315..21641)
                     /locus_tag="ACL8CG_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            22060..22347
                     /locus_tag="ACL8CG_001128"
     CDS             22060..22347
                     /locus_tag="ACL8CG_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS1343728.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            22399..24507
                     /locus_tag="ACL8CG_001129"
     CDS             22399..24507
                     /locus_tag="ACL8CG_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS1343729.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            24504..25145
                     /locus_tag="ACL8CG_001130"
     CDS             24504..25145
                     /locus_tag="ACL8CG_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343730.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            25352..26158
                     /locus_tag="ACL8CG_001131"
     CDS             25352..26158
                     /locus_tag="ACL8CG_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1343731.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            26175..27371
                     /locus_tag="ACL8CG_001132"
     CDS             26175..27371
                     /locus_tag="ACL8CG_001132"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HGS1343732.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQTGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKEN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPNSLYDENLATYTSADTVDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            27377..28219
                     /gene="argH"
                     /locus_tag="ACL8CG_001133"
     CDS             27377..28219
                     /gene="argH"
                     /locus_tag="ACL8CG_001133"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS1343733.1"
                     /translation="MDREVDVIWLRIQNYGVVALAGTTFPIDRQLSSDLLEFKQPYTN
                     SLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTFTTGSSIMPQ
                     KKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDTVETILNSLD
                     VLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVGRLVLDSIKS
                     AKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEYQIAVAKKAN
                     EAKK"
     gene            complement(28508..29371)
                     /locus_tag="ACL8CG_001134"
     CDS             complement(28508..29371)
                     /locus_tag="ACL8CG_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1343734.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            29837..32056
                     /locus_tag="ACL8CG_001135"
     CDS             29837..32056
                     /locus_tag="ACL8CG_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGS1343735.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDIILSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIIDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDIEEVTYG"
     gene            32049..32516
                     /locus_tag="ACL8CG_001136"
     CDS             32049..32516
                     /locus_tag="ACL8CG_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS1343736.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            32513..33865
                     /locus_tag="ACL8CG_001137"
     CDS             32513..33865
                     /locus_tag="ACL8CG_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HGS1343737.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADDKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNNPTSQAYNIYAQLISEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            34013..34318
                     /locus_tag="ACL8CG_001138"
     CDS             34013..34318
                     /locus_tag="ACL8CG_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPAR17_0115 family bacteriocin-like peptide"
                     /protein_id="HGS1343738.1"
                     /translation="MELILPNNYVDLEQEEMMYLDGGEPMSISAIVALAITIGGASYS
                     TGYVLGERVYYSGYKNSDYQKNKWGIRGAMLAAFGAIGAVVMLGFENRYYALVTGRG"
     gene            34652..35005
                     /locus_tag="ACL8CG_001139"
     CDS             34652..35005
                     /locus_tag="ACL8CG_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS1343739.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            35002..>35228
                     /locus_tag="ACL8CG_001140"
     CDS             35002..>35228
                     /locus_tag="ACL8CG_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343740.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILI"
BASE COUNT        10882 a         6119 c         7553 g        10674 t
ORIGIN      
        1 ttaagataaa tgttaaagaa acatcagaca cagcaaatgg ttcattatca ccttctaact
       61 ctggttctag cgtgactccg atgaatcaca atcatgctcc aggtactaca gatagcgtgc
      121 ctgctgacac catgacaagt tctaccaaca cgatggcagg tgaaaacatg gctgcttctg
      181 ctaacaagat gtctgatacg atgatgtcag aggataaagc tatgctacca aatactggtg
      241 agactcaaac atcaatggca agtattggtt tccttgggct tgcgcttgca ggtttactcg
      301 gtggtctagg tttgaaaaac aaaaaagaag aaaactaatc agctaaggaa ataaatgatg
      361 gatagtgggc tgactaagat tagtttaaca actcaatcag caatcaggac tttctttcaa
      421 tagcagatta aaatcatcgt aaaacaataa aaatagtgtt atacttaaag cagtatagca
      481 ctgtttttat caaaggagag acagatggga aagacaattt tactcgttga cgacgaggta
      541 gaaatcacag atattcatca gagatactta attcaggcag gttatcaggt cttggtagcc
      601 catgatggac tggaagcgct agagctgttc aagaaaaaac cgattgattt gattatcaca
      661 gatgtcatga tgcctcggat ggatggttat gatttaatca gtgaggttca atacttatca
      721 ccagagcagc ctttcctatt tattactgct aagaccagtg aacaggacaa gatttacggc
      781 ctgagcttgg gagcagatga ttttattgct aagcctttta gcccacgtga gctggttttg
      841 cgtgtccaca atattttgcg ccgccttcat cgtgggggcg aaacagagct gatttccctt
      901 ggcaatctaa aaatgaatca tagtagtcat gaagttcaaa taggagaaga aatgctggat
      961 ttaactgtta aatcatttga attgctgtgg attttagcta gcaatccaga gcgagttttc
     1021 tccaagacag acctctatga aaagatctgg aaagaagact acgtggatga caccaatacc
     1081 ttgaatgtgc atatccatgc tcttcgacag gagctggcaa aatatagtag tgaccaaact
     1141 cccactatta agacagtttg ggggttggga tataagatag agaaaccgag aggacaaaca
     1201 tgaaactaaa aagttatatt ttggttggat atattatttc aaccctctta accattttgg
     1261 ttgttttttg ggctgttcaa aaaatgctga ttgcgaaagg cgagatttac tttttgcttg
     1321 ggatgaccat cgttgccagc cttgtcggtg ctgggattag tctctttctc ctattgccag
     1381 tctttacgtc gttgggcaaa ctcaaggagc atgccaagcg ggtagcggcc aaggattttc
     1441 cttcaaattt ggaggttcaa ggtcctgtag aatttcagca attagggcaa acttttaatg
     1501 agatgtccca tgatttgcag gtaagctttg attccttgga agaaagcgaa cgagaaaagg
     1561 gcttgatgat tgctcagttg tcgcatgata ttaagacccc tatcacttcg atccaagcga
     1621 cggtagaagg gattttggat gggattatca aggagtcgga gcaagctcat tatctagcaa
     1681 ccattggacg ccagacggag aggctcaata aactggttga ggagttgaat tttttgaccc
     1741 taaacacagc tagaaatcag gtggaaacta ccagtaaaga cagtattttt ctggacaagc
     1801 tcttaattga gtgcatgagt gaatttcagt ttttgattga gcaggagaga agagatgtcc
     1861 acttgcaggt aatcccagag tctgcccgga ttgagggaga ttatgctaag ctttctcgta
     1921 tcttggtgaa tctggtcgat aacgctttta aatattctgc tccaggaacc aagctggaag
     1981 tggtgactaa gctggagaag ggccagcttt caatcagtgt gaccgatgaa gggcagggca
     2041 ttgccccaga ggatttggaa aatattttca aacgccttta tcgtgtcgaa acttcgcgta
     2101 acatgaagac aggtggtcat ggattaggac ttgcgattgc gcgtgaattg gcccatcaat
     2161 tgggtgggga aatcacagtc agcagccagt acggtctagg aagtaccttt accctcgttc
     2221 tcaatctctc tggtagtgaa aataaagcct aaaacccctt tacaaatcca gctattcatg
     2281 gtaaaatgga ttttgtgtga aatatcagca ggaaagcatg aagctcgtca acaggtgtct
     2341 tatgacaagt aaccttggct gtttaggcga agggcatctg cacgaatcag ggctttctaa
     2401 gtgactattt ccaccgaaat attatttata tcaggaggac attcatatgt cacgttatac
     2461 aggaccatct tggaaacaag ctcgtcgcct tggcctttca cttacaggta caggtaaaga
     2521 attggcacgt cgtaactacg taccaggaca acacggacca aacaaccgtt ctaaattgtc
     2581 agaatatggt ttgcaattgg ctgaaaaaca aaaacttcgt ttcacttacg gtgtaggtga
     2641 aaaacaattc cgtaacttgt tcgtacaagc tacaaaaatc aaaggcggaa tcctaggttt
     2701 caactttatg cttcttttgg aacgtcgttt ggataacgtt gtttaccgtc ttggtctcgc
     2761 gactactcgt cgtcaagctc gtcaattcgt aaaccacggt cacatccttg ttgacgggaa
     2821 acgcgttgat atcccatcat accgcgtaac tccaggtcaa gtaatctcag ttcgtgaaaa
     2881 atcattgaaa gttccagcaa tccttgaagc agtagaagct actcttggac gtccagcatt
     2941 cgtatcattc gacgctgaaa agttggaagg ttcattgact cgcttgccag aacgcgacga
     3001 aatcaaccca gaaatcaacg aagcacttgt cgttgaattc tacaacaaaa tgttgtaata
     3061 ttttattgaa taagataggc tttgatatta agcactttgg gacgttctcc cttagtgctt
     3121 ttttgatttc tcttagtatc cagctataat cgttgagaca taactagacc gatatagtcc
     3181 aaagtgatat agtaaaatga accaaaaata gtacacaatg tggtataatc cttttatggc
     3241 atattcaata gattttcgta aaaaagttct ctcttattgt gagcgaacag gtagtataac
     3301 agaagcatca cacgttttcc aaatctcacg taataccatt tatggctggt taaagctaaa
     3361 agagaaaaca ggagagctaa accaccaagt atagtgtatt gaatctataa cagtacacct
     3421 tggctgctaa aatatttcta taaattaatt tgactttcct gatagagttg ttcacatctt
     3481 atttcaaatc actataaaag ctctataatc tctttataag atttgcccat cagacgaaat
     3541 ataatggatt gaaactagaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     3601 tgactttcct gatcgatttg tcctgttctt gtttcatttt actatagaac gatttgaagg
     3661 cgtttatgat atttagctgt acgagagtct tttaaaagtg ttttgatggt ttggatttct
     3721 tctttagttg atttcatatc actgttatat aatgcttttt gattttagtc tagtattagt
     3781 aagcagactc aaaccttaga aaatcttttg agatcattga caggtgtatc gaatcctacc
     3841 acagattcag cacgtctggt tttggcagag gctaagaaag cttttgcaga tgatagtttg
     3901 acagagcaag gtttacgtga tatcttgcaa acagtcaaag atgccattgc ttccctagag
     3961 tccattaagg aaagccagtc agcaactaag gatggaggac aaacagcggg caaagaaaca
     4021 gcaggagaag atgagtctgc aaatcaaact caagaaatta gccaaggaat taagtaaact
     4081 tcttaaagac tcaaaccttg aaacagtaga taaggatgtc cttgaaaact ctcaaaaaga
     4141 acttcaaaaa gcagttttgt tcttggcaga tgaaaaaggc tctgagcata ctgaagcaga
     4201 ggtgattgat aatcttaaag aggttattgc taagttgaaa gcaaacgcct aataacatat
     4261 taaaaatctc cagattagga actatcgctg agttccctag tctggagatt tttcagtata
     4321 ccccgttgtt ggatgcttat aacagagtga cgccatcact gggctaatag agataaaata
     4381 aacaattgat ttaggacatt tgtttgatag tggtgataaa gttttaaatc tgctacataa
     4441 tttgtggagt tttttctata attaggagtt taacctaacc tgcaaatagg agtatactaa
     4501 taatgtaatc gttatcaaaa gtctaaaaaa gaatttttag atggatatca aaataaaaag
     4561 ggaggaaatt atgaaaaagt tttcaaaaac attgagagac aactggatct ttctcttgat
     4621 ggttttgcca ggggcactct ggttgattct attcttttac attccagtat ttgggaacgt
     4681 ggttgccttc aaagactacc acatgaccag taatggtttc atagatagta tcataaatag
     4741 taaatgggtc ggactcgata atttcagatt cttatttagt tcaagagacg cctttattat
     4801 cacacgaaat accgtcctct acaatcttgg ctttatcttt ctaggtttag ttgtatctgt
     4861 agggattgcc attatcctca gcgagctccg ttctaagaga atggtgaaga ttttccaaac
     4921 ttctatgttg ttcccttact tcttgtcttg ggttatcatc agtttcttta cagatgcctt
     4981 cctaaatatt gataaagggg tgttcaatca tctattggaa agtcttggtc tcaaagaagt
     5041 caatttctac gctgacctgg gcatctggcc ctatctccta cttttcctag gtatttggaa
     5101 aggttttgga tatagcagtg tcatgtacta tgcgacgatc atgggaattg atccaaccta
     5161 ctacgaagca gcgacagtgg acggagctag caagtggcaa cgtattcgca acgtaaccat
     5221 tcctcagttg actccgcttg taactgtatt gaccatcctt gcagtcggaa atatcttccg
     5281 cgcagacttc ggtctcttct atcaaatccc acacaatgct ggtcagcttt acaatgtaac
     5341 caacgttttg gacgtatatg tttttaatgg tttgactcag acagcagata tcggtatggc
     5401 tgcagcagcc ggtctttacc aatccgttgt tggtttgatt ctggttatcc tatcaaactt
     5461 gcttgcaaga cgagtcgatc caaactcagc tttgttctag aaaggaggag aatatggcaa
     5521 aaaagaaaat taaaaaagaa aaaattgata atgtcggcat tcactccttc agtaagaaag
     5581 cagatatctt cttcagtatc atttcgggtt tgattgccct ctcttgtatc ctaccttttg
     5641 tattcgttat cattatttca gtgacagacg agaaaagcct cctccaatac ggctatagct
     5701 tcttcccatc ccaatttggc ttagacggtt ttgagttttt ggcacagttt aaggataaaa
     5761 tcctacaagc cctcttcatc tctgtctttg taaccgtagt tgggacattg acaaatgtct
     5821 ttatcacaac aacctatgcc tacgctattt cacggacaac ctttaagtat cgcagattct
     5881 ttaccatctt cgttctgctc agtatgttgt tcaacgctgg tttggtacca ggttatatca
     5941 tggtgactcg tgtgcttcag cttggggata ctgtttgggc cttgattgtt ccaatgcttc
     6001 tctcaccatt taacatcatc ttgatgcgtt ccttcttcaa gaagaccatt ccagaagcca
     6061 ttctagaatc ggctcgtatc gatggtgcca gtgaagcccg gattttcttc caaatctgtt
     6121 tgccattgtc actaccaggt atcgcaacca tcacgctctt aacagctctt ggtttctgga
     6181 atgactggtt caacgccctt ctttacatca agagtgacaa cttgtatcca ttgcaatatt
     6241 tgctcatgca aatccaacaa aatatggact acattgccaa agcggtcggc ttgactggtc
     6301 aactgggagt tgctctaccg aaagaaacag gtcgtatggc catggttgtg gttgcaaccc
     6361 ttccaatcgc gattttgtat ccatttttcc aacgctactt tgtaaaaggt ttgactatcg
     6421 gtggtgtgaa agaatagtgc ttattgagaa ataacatttc tcagttccca acttcccttg
     6481 tgtgaagtta atactcttcg aaaatcaaat tcaaaccgtg tcaacgtcgc cttgccgtag
     6541 atatatgtaa ctgacttcgt cagtcttatc tacaacctca aagcagtgct ttgagcagcc
     6601 tgcggctagt tttctagttt gctctttgat tttcattgag tataagatca ttacattgtt
     6661 tataagttta aaaataaaaa aaggagtttt tatcatgaaa aactggaaaa aatatgcttt
     6721 tacatctgct agtgtagtcg ctctggctgc aggtcttgct gcttgtggaa atttgacagg
     6781 taacagcaaa aaagctgctg attcaggtga caaacctgtt atcaaaatgt accaaatcgg
     6841 tgacaaacca gacaacttgg atgaattgtt agcaaatgcc aacaaaatca ttgaagaaaa
     6901 agttggtgcc aaattggata tccaatacct tggctggggt gactatggta agaaaatgtc
     6961 agttatcaca tcatctggtg aaaactatga tattgccttt gcagataact atattgtaaa
     7021 tgctcaaaaa ggtgcttacg ctgacttgac agaattgtac aaaaaagaag gtaaagacct
     7081 ttacaaagca cttgacccag cttacatcaa gggtaatact gtaaatggta agatttacgc
     7141 tgttccagtt gcagccaacg ttgcatcatc tcaaaacttt gccttcaacg gaactctcct
     7201 tgctaaatat ggtatcgata tttcaggtgt tacttcttac gaaactcttg agccagtctt
     7261 gaaacaaatt aaagaaaaag ctccagacgt agtaccattt gctattggta aagttttcat
     7321 cccatctgat aactttgact acccagtagc aaacggtctt ccattcgtta tcgaccttga
     7381 aggcgatact actaaagttg taaaccgtta cgaagtgcct cgtttcaaag aacacttgaa
     7441 gactcttcac aaattctatg aagctggcta cattccaaaa gacgtcgcaa caagcgatac
     7501 ttcctttgac cttcaacaag atacttggtt cgttcgtgaa gaaacagtag gaccagctga
     7561 ctacggtaac agcttgcttt cacgtgttgc caacaaagat atccaaatca aaccaattac
     7621 taacttcatc aagaaaaacc aaacaacaca agttgctaac tttgtcatct caaacaactc
     7681 taagaacaaa gaaaaatcaa tggaaatctt gaacctcttg aatacgaatc cagaactctt
     7741 gaacggtctt gtttacggtc cagaaggcaa gaactgggaa aaaattgaag gtaaagaaaa
     7801 ccgtgttcgc gttcttgatg gctacaaagg aaacactcac atgggtggat ggaacactgg
     7861 taacaactgg atcctttaca tcaacgaaaa cgttacagac caacaaatcg aaaattctaa
     7921 gaaagaattg gcagaagcta aagaatctcc agcgcttgga tttatcttca atactgacaa
     7981 tgtgaaatct gaaatctcag ctattgctaa cacaatgcaa caatttgata cagctatcaa
     8041 cactggtact gtagacccag ataaagctat tccagaattg atggaaaaat tgaaatctga
     8101 aggtgcctac gaaaaagtat tgaacgaaat gcaaaaacaa tacgatgaat tcttgaaaaa
     8161 caaaaaataa tcagctaaat tgatttcgtg tattcattcc taactcctaa aataagaatc
     8221 actgctttcc tcaggttggt ctggggaggg cagtggtttt tttggcacaa ggatatagat
     8281 atccatgttt tctcttgtcc ttattttaac cattcaggaa atttcgagaa ccctctacaa
     8341 tttccagtca aataaattgc attcgttttc tcaagcaggt atactagtat ggataaataa
     8401 aaaatttaga aaatttaaga atagaaaaga gaacaaatct tatggcaaaa gatattcgtg
     8461 tcttacttta ctacctttat actccaattg aaaatgcaga gcaatttgct gcagaccact
     8521 tggctttctg taaatcaatc ggccttaaag gccgtatcct agtcgctgac gagggaatta
     8581 acggaacagt ttcaggtgac tatgaaacaa ctcaaaaata catggactac gttcacagcc
     8641 ttccaggaat ggaagaactc tggttcaaga ttgacgaaga aagtgaacaa gccttcaaga
     8701 agatgtttgt tcgctacaag aaagaaattg tccaccttgg tttggaagac aacgactttg
     8761 acaatgacat caacccactt gaaacaacag gtgcttactt gtctccaaaa gagttcaaag
     8821 aagcgcttct tgataaagat accgttgtcc ttgacacacg taatgattat gagtatgacc
     8881 taggacattt ccgtggggct attcgcccag atattcgcaa cttccgtgag ttaccacaat
     8941 gggtccgtga taacaaggaa aaattcatgg acaagcgtgt cgtggtttac tgtacaggtg
     9001 gcgttcgctg tgagaaattc tcaggctgga tggtccgtga aggctacaaa gatgtcggcc
     9061 aattgcacgg aggaatcgca acttacggta aagacccaga agttcaaggt gagctttggg
     9121 atggaaaaat gtacgtattt gacgagcgta tcgccgttga tgtcaaccat gtcaacccaa
     9181 ccatcgtagg gaaagactgg tttgatggaa caccatgtga acgttatgtc aactgtggaa
     9241 atcccttctg taaccgtcgt atcttgacat cagaagaaaa tgaagacaag taccttcgtg
     9301 gatgctcaca cgagtgccgt gttcacccac gtaaccgcta tgtttcaaaa aatgaattga
     9361 cacaagctga agtgattgag cgcctagccg ctatcggtga aagcttggat caagcagcta
     9421 ctgtataaga tcaaacagtc ctcaggggct gtttttctat gctttgtact caaaaatcta
     9481 aagtttgttt ctgtatcttt cagaaaaata aggtatactg tatgtaaacg atttcaaagg
     9541 agtccagtta tggcaaaaac attttttatt ccaaataaac agagcatttt aggagaacaa
     9601 gagattttga atgccaagtc gatcttggcc ttgctagacg gtttggagtc acatagctat
     9661 gatgtagtct atctccgtca gcctcttaat cgtctcgaat atatcgagtg tgcgatagtg
     9721 gggcaatcac aatttctctt taaggtcagt tatgctgatg gtcaaaaggc ttaccgtgtc
     9781 gatcttcctg acctactaac aaagacagac tggcagatta tcaagtcatt tttagatgct
     9841 ttgcttgctt atacagggac tgatattgaa gggctagatg gttttgattt tgaagcttat
     9901 ttccaagcaa gtattcaagc ctatctagca gaccctgtag ctcgttttac gatttgccaa
     9961 ggaattttta atcctatttt ctttagtcgt gagaacttga aaagcttttt agaggcagat
    10021 ggcttggctc agtttgaagc gcgtgtgcgt gcggttcaag agacagatgc ctactttgcg
    10081 agagtttcct tctatcagga tggagaagga aaagtgcatg gcgtttacca tctagctcaa
    10141 ggagtcaaga cagttttacc gagagaaccg tttgttcctg cagcctatat tgagcaattg
    10201 gtggataagg aagtgcagtg ggagattgac ttggttcaaa tcacaggaga tggctctaaa
    10261 ccagaagact atgaagccat tgcccgcttg gactatgcaa aattcttaga ggtattaccc
    10321 ctatcttttt accaccaact agacgccaat caaatagaag tgcaacccat attagacaaa
    10381 gattttaaag cattagcaca agaagagtaa agcagaagca ggtcaatcga cttgcttttt
    10441 tgacatagaa aaaatcctgc caaggatgac aggattgcta ctcaatgaaa atcaaagagc
    10501 aaactaggaa gctagccgca ggctgtactt gagtacggta aggcgaagct gacgtggttt
    10561 gaatttgatt ttcgaagagt atgaagttta aagaaaggcc aagatacgaa gataatctcc
    10621 aatcagtgcc acttcagcta caaagaagag gaggataata actccgttca caaggacaga
    10681 caagaataat tgatagaagg agtcggtttc acttgcttga cttggtcttg taatgatatg
    10741 gagactggca agcagaatga ttccaatgct aatcacacac aagagagctg taaatcgtag
    10801 gctatcaaag aaagcaaaga aactagcaat agcagtgagg aagattggaa ttgccaagag
    10861 ttgactatat tgttggagaa ccttgtctag cgtccagtcc ttttcctggt ggataaatcg
    10921 tctcacaacg aaactaccca agaggaatga aaagaagaag agtgttgtcg ctactaggat
    10981 agagacgata gaaaaaagag ttaaaggagc tagctgctca gggaagcgac tgttaatgct
    11041 tgctatatgt ccatagtaag catgtttgat gtgatagata ctaaagaaaa aggaagatgc
    11101 agaaaacaga atgagcaaga gaaaggctgt gtaactgtgt gtgatacttg tttccaactt
    11161 acttgtagga gatttgatcg cttccactag ccaagaccaa aaatcaagca cttgctcttt
    11221 ccatttatcc ctagattttg gagcttggtc ggggatataa ggactttcta aagatttact
    11281 gataagaagt ggctctttcg tggttgcttt ttgctgagga agagcttctt ggctctcttc
    11341 agctatagtg actttttctg tttctttaga aaggtctgac tcttcttcag tagaattaga
    11401 tgccttcttt tcttctattt ctgttctcgc ttcaccgact tcaggagttt caattttctc
    11461 ttcttgctgg ctttccagtt cgacttcagc ttgagagact tcctcctcta cttgagtatt
    11521 ttttccaatt ggtgtatcga aatcggctat cgtttcttca gccttgtctg caacctcttg
    11581 agcttgctct tcaggcttgt tcttgcttgt tgtttttaca aaatcattac tttcaaacca
    11641 ttcttgtttc atggtagaac ctccttttgg ttagataaat atgcttccat agtagcagat
    11701 gtaagcgttt ttgtcaacgt ctgcttggtg tggatattag atcaatatta tcatcagatc
    11761 tcgcaatgag ttgatccttg acatcggttt tttcagtttt gtaagggttg cttaattccg
    11821 tacctcttga ttcaggcttt tctcttgtga attggaagat agaaccgtag ttacttgaga
    11881 tgtcccagtt aattcgttgg ctttctttct ggtctaggat gattctgaga taatctttgg
    11941 cagtcagttc aaccttacca tggacttgga tattttcagc gtggaagtga ttatctgttg
    12001 actctagctg actatctgta agaactgtat caaagatatt aacgatattg ggcgttgtga
    12061 gtttactgtt tttgatacga cttccttcaa ttcggaggat atagctgttt gtattgaggg
    12121 tcgcattttc aaggctagca tttatgatgg tggtttgtcc gcgattggct gagatgttga
    12181 tcccttttag agttctccct tttggtagtc ggagaataac ttcttcaaaa cgactagagt
    12241 agctacttgc gatatgaaga atcccaccaa ttccagaaga gagaaacgga gtttcagaca
    12301 gtttcttatc agtgagactc agagttctat cgttctgatt ggtgataaaa tcatggtgag
    12361 cagaaagaga tggatggtaa gaaatgtgga tttgatcatc gaaagagtct gtgatggtga
    12421 gcgtgtgttg gtggagagta atttctaggt tttcgacttc cttgccaaag gttagctttt
    12481 ccgtacggct atcatagaca ggttctttgg acatggaaag taggctctta atcccgtcag
    12541 attggatacc tacaaaaagc aggataaagc cgataacggt agtcaccaca ccaaagatga
    12601 gaaatccttt tgtccattta cgcatgctga ttacctctct ttcctttttt aagaacaaat
    12661 tgtaccagac gaacaatgag tagaccgaag aagcgagcta cataggaaat gccaagtaaa
    12721 actagcgaag aagcaccgat agccagtaaa ccagaaccaa aaatcaagat aaaggctgat
    12781 ttggcttggg cgaggatagt gaaactttca actaaaaata ggaatccgcc gatgataccc
    12841 agtatggaaa ctgcaaagaa agccagaatg acagtcaaag cggctacaag gattgcgaac
    12901 agggtcacga ggatggcgat tcccagagga atgccgatag gtgctgcaag gagggctaac
    12961 aaggcgatat gtaaaatttg tcggttattt ttttgagcgg gtgcttcatt gattttttta
    13021 tcgagaagat tggatagaac ttcgtgggcc gcttctttgg gagttcccaa actagcgatg
    13081 agttcttctt ctccttcgac tccagcatcg tcaaagagct ctctgaaata gtccatggct
    13141 tcgatacggt cagcttcagg tagtttcttg agatagagtt ctagctgagt caggtattca
    13201 gttcttgtca tggcggatac tcccttctat gatgccattg atggtgtctg tatagagtgt
    13261 ccattcatct tttagggtca agagctgctc tataccaccg tttgtcaagg agtagtattt
    13321 gcgcatgcga ccttggaact ctctagaata ggttgtcaga aagctattgc cttccaattt
    13381 tttgagaatg ggatagagtg tggattcttt gatattagcg atcagcttaa tggtttggct
    13441 aatctcataa ccataagaat caccctgctc cagtacagcc aagatgagaa attcaatcaa
    13501 ggcagaggat gttggaaagt acatgggaaa cctccttttc taatgtgtaa gatttttata
    13561 tataattttt ctacacatac attgtacatc taaaagaaag ccctgtcaag agaaatgtgt
    13621 aaaattttta tatataaaaa acttctagct aaaactagaa gtttaaagga tcttatccgc
    13681 tctgtccact gtaaagaggg ccacagtcat caggatatag atgagcaaga gggcagctac
    13741 agctggtacc caagagtgga acaggtcaaa actgtaacca aagagggttg gcccaaaggc
    13801 tgctaggata tagcctcctg tttgagatag gccggacaat tgggctgtct tttcaggggc
    13861 gcttgtcttg agtgaaaagt tgaccatgag ataagggaag agggcgctgg ttgcggttcc
    13921 gatgaggaga tggatggtaa gccagtaaat gaaattattg attgggaaaa agagcatgga
    13981 aatgccgacc acaccagcta gtgaaaccag agtgagcatg agctgacggt tgcgagtaga
    14041 taaactggtt gtcaggcttg ggatggtcat tgaaaaagga atgctaatca gagataagat
    14101 agaagtcagc aagccagctt cgtgactgga tagacctgca tggatagaca tggtaggtaa
    14161 ccaggtcatg acggtgtaaa agatcaagga ttgaaaacct gaaaagataa taattgccca
    14221 aacctgttta ttacgcatga cctttatttg acttttttgt ttggtttgtg gagctagtct
    14281 atgattatag cggtgatttg ggagccagac caaaaaagtt gctagacaga gtaacgtgag
    14341 gaggaggata agtcctttcc aagaactggc ttgtgtaatg ggcacagcta gataggaagc
    14401 cagagccgtt gcaatcccca tagacgttac atataaggtg gtcagaaaac caattttctt
    14461 tggttgattg gcttggataa gactaggaag caggacattg atgactgcga cacttgcccc
    14521 aaccatcaag gttcctagat agagcagggg cagattgatt agtcgaatga gtgagccgat
    14581 ggtcaagaag aagaggctgt aggtgaagag atgctccaag ccgattttct gagccagtcg
    14641 ggtagaaaat ggtgaaaaga gggtaaacat aaggagaggc aggctggtca agacaccaag
    14701 cgaactaact tctacctcca gaccttgcga aatatttccc aaaataatgg gtaaaacagt
    14761 aaaaggagtt cgcaaggaaa caccaatcag gataatacct ggaacaaaaa agagtgattg
    14821 ctttttcata taatacctct tctagctgat tttaataaca gcttatttta aggctttttc
    14881 actataatgt caagtaaggt ttctggcttt caagataaaa atgggaaagt cttgaaaatt
    14941 atgatagaat ggtggaagga aaaattcagg agagtagtag tgactcaaaa tgttgaaagt
    15001 cttctcgtat ccattgtaat cagtgcatac aatgaagaaa aatatctgcc tggtctaatt
    15061 gaagacttaa aaaatcaaac ttatcctaaa gagaatattg aaattctatt tataaatgct
    15121 atgtccacag atgggaccac agctatcatt cagcaattta taaaggaaga tacagagttt
    15181 aactcaatta gattgtataa caatcctaag aaaaatcaag ctagtggttt taacctggga
    15241 gttaaacatt ctgtagggga ccttatttta aaaattgatg ctcattcaaa agttactgag
    15301 agttttgtaa tgaacaatgt ggctattatt caacaaggtg aatttgtctg tggggggcct
    15361 agaccgacga ttatcgaagg aaaaggaaaa tgggcagaga ccttgcatct tgttgaggaa
    15421 aatatgtttg gcagtagcat tgccaattat cgaaatagtt ctgaggatag atatgtttct
    15481 tctatttttc atggaatgta taaacgagag gttttccaga aggttggttt agtaaatgag
    15541 caacttggcc gaactgaaga taatgatatt cattatagaa ttcgagaata tggttataaa
    15601 atccgctata gcccaagtat tctatcttat cagtatattc gaccaacatt caagaaaatg
    15661 ctgcatcaaa agtatttaaa tggtttgtgg attggcttga caagtcatgt tcagtttaag
    15721 tgtttatcat tatttcacta tgttccttgt ttatttgttt tgagtcttgt gtttagtcta
    15781 gcattgttac cgatcacatt cgtattcata actttactat taggtgccta ttttctactt
    15841 ttgtcactac tcactttgct gactttatta aaacataaaa atggatttct aattgtgatg
    15901 ccctttcttt tattttccat tcactttgct tatggctttg ggacgattgt aggtttaatt
    15961 agaggattta aatggaagaa ggagtacaag agaacaataa tttatttgga taaaataagc
    16021 caaataaata aaaatatgct ataataacaa tatagtaaaa ctcttttaag gaggagtaga
    16081 tttctatgaa taaaaaacta acagattatg tgattgatct ggtggaaatt ttaaataaac
    16141 aacaaaagca ggttttctgg ggaatatttg atattttcag tatggtggtt tccatcattg
    16201 tatcttatat tttattttat gggctgatta atccagcacc tgttgactac attatctata
    16261 cgagtttggc cttcctgttc tatcaattga tgattggttt ttgggggttg aacgcgagca
    16321 ttagtcgtta cagcaagatt acggatttca tgaaaatctt ttttggtgtg actgctagca
    16381 gtgtcttgtc atatagtatc tgttatgcct tcttgccact cttctccatc cgtttcatca
    16441 ttctctttat cttgttgagt accttcttga ttttattgcc acggattact tggcagttaa
    16501 tctactccag acgcaaaaaa ggtagtggtg atggagaaca ccgtcggacc ttcttgattg
    16561 gtgccggtga tggtggggct ctttttatgg atagttacca acatccaacc agtgaattag
    16621 aactggtcgg tattttggat aaggattcta agaaaaaggg tcaaaaactt ggtggtattc
    16681 ctgttttggg ctcttatgac aatctgcctg aattagccaa acgccatcaa atcgagcgtg
    16741 tcatcgttgc gattccgtcg ctggatccgt cagaatatga gcgtatcttg cagatgtgta
    16801 ataagctggg tgtcaaatgt tacaagatgc ctaaggttga aactgttgtt cagggccttc
    16861 accaagcagg tactggcttc caaaaaattg atattacgga ccttttgggt cgtcaggaaa
    16921 tccgtcttga cgaatcgcgt ctgggtgcag aactgacagg taagaccatc ttagtcacag
    16981 gagctggagg ttcaatcggt tctgaaatct gtcgtcaagt tagtcgcttc aatcctgaac
    17041 gcattgtctt gctcggtcat ggggaaaact caatctacct tgtttatcat gaattgattc
    17101 gtaagttcca agagattgat tatgtacctg tgattgcgga cattcaagac tatgatcgtt
    17161 tgttgcaagt ctttgagcag tacaaacctg ctattgttta tcatgcggca gcccacaagc
    17221 atgttcctat gatggagcgc aatccaaaag aagccttcaa aaacaatatc cgtggaactt
    17281 acaatgttgc taaggctgtt gatgaagcta aagtgtctaa gatggttatg atttcgacag
    17341 ataaggcagt caatccacca aatgttatgg gagcaaccaa gcgcgtggcg gagttgattg
    17401 ttactggctt taaccaacgt agccaatcaa cctactgtgc agttcgtttt gggaatgttc
    17461 ttggtagccg tggtagtgtc attccagtct ttgaacgtca gattgctgaa ggtgggcctg
    17521 taacggtgac agacttccgc atgacccgtt actttatgac cattccagaa gctagccgtc
    17581 tggttatcca tgctggtgct tatgccaaag atggggaagt ctttatcctt gatatgggca
    17641 aaccagtcaa gatttatgac ttggccaaga agatggtgct tctaagtggc cacactgaaa
    17701 gtgaaattcc aatcgttgaa gttggaatcc gcccaggtga aaaactctac gaagaactct
    17761 tggtatcaac cgaactcgtt gataatcaag ttatggataa gattttcgtt ggtaaggtta
    17821 atgtcatgcc tttagaatcc atcaatcaaa agattggaga gttccgcact ctcagtggag
    17881 atgagttgaa gcaagctatt atcgcctttg ctaatcaaac aacccacatt gaataaaaaa
    17941 gaaaaacgca tagtatcaag ttacacaacc ttggtaatat gcgttttatt atgtagagac
    18001 ttatactctt cgaaaatctc ttcaaaccac gtcaacgtcg ccttgccgta tgtatatgtt
    18061 actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga cttcgtcagt
    18121 tccatctaca accttaaaac agtgttttga gcagcccgca gctagtttcc tagtttgctc
    18181 tttgattttc attgagtatt acttcatttt cttctgaaat agagttgtcg cccagtctat
    18241 gctattgaaa atacgccaaa acttctaagg gtttgtgagc gatataatca ggttgatagt
    18301 ttagtagatc tgcttgctct ccaaatcccc aagtgacggc caatttctga atacctgttt
    18361 ctcgagctcc cagcatatca aacttggtat ctccgatgat gatggcttgt tctggtgcta
    18421 gttgatgtgt ctgtaaggct tggtgaatga catctgcctt atggggtgct tcagggctag
    18481 aaccataaat accatcaaag aaatgatgga tttccaagtt tttggccatg tcttgagcag
    18541 tagatgtatt ctttgtcgtg gtgatgtaga gtggataact gctcgataac tcctcaagca
    18601 agtctataat ctgaggaaag agttgagctt catagatgcc ttttgcctta tagtaagaac
    18661 gatatatctg catggcttca gaaatttggt ctttggacag gcaggtcgca aaactacttt
    18721 cgagaggtgg tcccataaaa ccacgaatag ttttggcatc agggctaggc acccccagct
    18781 ctttaaaggt ataggtaaag gcattgtgaa tcccgataga actatcaacg agggttccat
    18841 ccaaatcgaa aaaaatcgct gtgatagagg tcatggtttc tcctatttga taagcttatt
    18901 ctccgaaaat ctctttttgg aggcgacgac cagtaggggt ggtagcgagt ccaccttcag
    18961 ctgtttcacg aaaggcagtt ggcatgcttg ctcctacttg gtacatggca tcgatcactt
    19021 catccacagg gattttagat tcgatacctg ccaaggccat gtctgctgcg atgaaagcaa
    19081 agctagctcc catggcatta cgtttgacac agggaacttc gaccaaacct gcaacagggt
    19141 cacagatgag gcctagcata tttttaatga caaaggcaat agcttgactg gcctgataag
    19201 gtgttccacc tgcagccaga gtcaaggcgg cagcactcat agcagaggct gaaccaactt
    19261 cagcttgaca tccaccctca gcacctgaga tggaggcatt gtttgcgatg actagtccaa
    19321 aggcaccagc agcaaagagg aaatccaatt gttgctcgtg gctgaggtct aatttttcaa
    19381 tagcagcagt gagaacggaa gggagacaac cggcacttcc tgcggtagga gtagcgcaga
    19441 ccaagcccat tttagcattg tgttcattga ctgcgatagc atttcgggca gcagagagaa
    19501 tcgtgtaatc tgataaagtt ttttcgtttt tgatgtagtg atccaatttg gcagcatctc
    19561 cacctgtcag gccactacga gatttatttt cattgaggcc aagttggaca gaggctttca
    19621 taacttccag attgcgttcc atgagaagga agacttcttc acgttcgcga ccggtcaatt
    19681 caaactctgt tgtaatcatg agttctgcga catttccttg aaagtccaga tctgcttgct
    19741 cgaccaattc tttgatagaa taaaacatgc ttcctcctat ttaaagaaat tgacattgtg
    19801 gagatgaggg atttttcgaa tttcttcgat agcctcatca cagttgcgac tgtcaacttc
    19861 gataatcata atggcttttt caccagcttt ttcacgagtg acattcatct gggcgatatt
    19921 gataccatag cgggaaagcg cctctgtaac aagggcaatc atacctggaa tatcttgatg
    19981 aacgatgatg atagtcggtg tattcatatt gagagagacg gcaaaaccat tgagttcggt
    20041 tacctgaata tttcctccac cgatagaaat accagtcacg ctgatggtct tgtgggcatt
    20101 tttaacagta attttagtgg tgttagggtg aggggcattg ctgtctttct gaatggtcca
    20161 gacaatcttg ataccacgct tgtgggcaat ttccagacta tttggaattt caggatcatc
    20221 tgtatccatt cctaaaatac ctgcaacaag ggctaggtct gttccgtgac cacgataggt
    20281 cttggcaaat gagttaaaaa gttggaattc aacttctgtc ggagtatcat caaaaatgga
    20341 agagacaatc ttcccaatac gaacagcacc agcggtatgg ctactagatg ggccaatcat
    20401 aactggtccg atgatatcaa agacagattg aaaacgaagt gatttcatca gtttcccctt
    20461 ataaaaattc ttatctctat tatatcaaag aatgaggggc ttggctttaa ttgtggatga
    20521 aaacctttct aatacctcaa atagcataaa aatagtatct tttatgacaa aaaacacctt
    20581 atttagggaa ataaaaaata attttgtaat atttctacat aaaagtgtca agaaacggta
    20641 atatttaaag ggtatgatag aactatagaa agaaggagaa ttttcgaata tgaaatcaat
    20701 aactaaaaag attaaagcaa ctcttgcagg agtagctgcc ttgtttgcag tatttgctcc
    20761 atcatttgta tctgctcaag aatcatcaac ttacactgtt aaagaaggtg atacactttc
    20821 agaaatcgct gaaactcaca acacaacagt tgaaaaattg gcagaaaaca accacattga
    20881 taacattcat ttgatttatg ttgatcaaga gttggttatc gatggccctg tagcgcctgt
    20941 tgcaacacca gcgccagcta cttatgcggc accagccgct caagatgaaa ctgtttcagc
    21001 tccagtagta agtgaaacag ttgtttcaac tgtaagcgga tctgaagcag aagccaaaga
    21061 atggatcgct caaaaagaat caggtggtag ctatacagct acaaatggac gttatatcgg
    21121 acgttaccaa ttaacagatt catacctgaa cggtgactac tcagctgaaa accaagaacg
    21181 tgtagcagat gcctacgttg caggacgtta cggttcatgg actgctgcta aaaacttctg
    21241 gcttaacaat ggctggtatt aagaactaac gaacaaataa tatgtaaaag gtcgaggagc
    21301 tccctcgact ttttttataa tttctttggt tgataatggg tctctacttc ttttttgaga
    21361 tgagacagca tagaagtttc ctcggtcagc tccagaagtg agaaaccttt ttggataagt
    21421 ttagcattat ctgtacaaat cccaatacgg acatagcaga tagcaagcct atcgtagctt
    21481 ttcttattct tggcgtcctc cagtaaagtg tagcagattt gcttacacat gtttttatct
    21541 tgattgtata gatagagtgt ggaaaggttt agcaggattg ctattcgcaa gtcatataaa
    21601 tgttgatagt ttttatagac ttctaagcgt tgcaagattt tctcggatta ttgacaaata
    21661 aacggacatt ctgatagacg attgccctag cggcttagtg taaactttac aaatttggct
    21721 tgtaattttt ttataaaatt cacttcagtt acttgacagt tattatattt tcgcttatta
    21781 tatagataaa aggatgggat aggattttaa aaatttgaaa gcgctatcca tattgtttat
    21841 tggactgatt cttgagtaat agttagagtg tgcttaatac tactctggtt gttcaaggac
    21901 ctgatacaga agcgcaccat tctcccggtt aagagtaagt tcgttgttaa aaaatgaaat
    21961 gagatagaag gaaggtgagt ccaatggact acgatacttg ttgataaatt actatagctg
    22021 tttttacgga acagctctcg ataataggag aaataaatca tgagaaaatt agttaaaatt
    22081 ggtgttgcat ctttaatggt atgtggtata cttgctacta caaatgcttt agcagtatgg
    22141 gttgagggtg gtcaatggaa ctatggagta ggttggacag gaacttttgg atattctgat
    22201 tacttacatt ctactcgata tcatacagca actgttagac atgggggtag aacctctaag
    22261 gattatgcaa aacctgaggc atgggctaga gcttccctca ccaagattcc gccaacagga
    22321 atggaatatt tctatggatt tgagtaaaat tcttccctct cctatttgga gagggaaaac
    22381 tgtagtggag gcacttttat gaaaaaaatc agtaatttct gtatgttact cctgcttctg
    22441 tgtaccactt tttttgtttt taatgtaaac tatacacgag aagtggttcg gattcaagaa
    22501 atgggaaaga ctgtagattc tttggatttg tatttgaaag atattaacga acctgcagcg
    22561 tctgttcttc gattttttga ggatgtatca aaggagtata aagtctccat catcaaaaca
    22621 gacagtggtg atgaggtggt caagtctggt gtttttgata aagatacctt cccctaccaa
    22681 gagtttggga tttcttctct tgattttacc acagatggtg aaggagtcta tagtaataaa
    22741 gaaatttcca ataaacttgg tacgattccg acctttctaa aagccaaacc tattcagctt
    22801 atgacttttc aaacctatat caaggataca tctcgtagtt taaatggtcg ctatacgata
    22861 acttctacac aagagatgga caaggatagg attgtacaga aatggagcga ttttttcaag
    22921 atagaccagg ctaccttgct agagccgacc tacaaaagtg cagtggaagt cataaatcga
    22981 gatttgcttt tatctgccat tgtttttgtc ttggctattt tgcttcttgt gttagtgaca
    23041 gtgtatcaac cgatgatgga gatgaaaaga gttggggtac aaaaattact tggttttcaa
    23101 gatagggctg ttttagctga tgttgtaaaa ggcaaccttt acctcctcct aggtggggct
    23161 cttgtgatca atctaggcgt gtttttcttg cttgattata agccaaaaga tttgtttcct
    23221 atgctgtggt tgtctcattt tttgctgttg cagctttatc tctttatcag ttggttgact
    23281 tacctcttaa tccaaaaaat gacaatcagc tctctgctga aaggtttttc atctttcaaa
    23341 tttggtctta tcttcaatta tgtgatgaaa atagggacaa ctattttact gacggcctta
    23401 ctgattgggg tgggcagaag tttagaacaa gaaaacaaag aacttgctta tcagcaacag
    23461 tgggtaagtc aaggtaatta cctgacctta gaaaccttca aactcaatga taatctgtgg
    23521 caagaagagc tagcagggtc agggaaatct acagattatt tctatcgatt ttatcaggat
    23581 ttggtagaaa aaacgcaggc gggctatgtg cagagtagca gtcttcctgt aaaaaatttt
    23641 gtccaatcag aacagattca gcaatatcag ttaacagata cggtggatgt ttactatgcc
    23701 aatcgcaatt ttctaaagag caagggattc aagctaccag ataccggtat taaaaaagtt
    23761 attttgatgc cagcaagtac gaaaggtgaa gaagataaaa atcagctctt ggggaagtta
    23821 attgcctttc attcgatgaa gtatgaagag cagcaaaaac gaacgataga ggagatggat
    23881 gtcgagattg cctattatga aggagattgg tcatttttcc catatagtga taagcgaaag
    23941 gaaaatctct ccaatccaat tattagcttg gtcaatgatt ctgatatgat gtgggatgag
    24001 aaagcctccc tgtcaacaac tggcttaaat aatccgatta aaattgaaaa tacggttcaa
    24061 catcaaaaag agattacaga gttagttgag aaattgtcag atggaaatta tttaaaattt
    24121 tcatctattc aagccattca acaagagaaa gtggattctt atcgagatgc tgttcggaat
    24181 tttaacctac tctttgcttt gtttggtctc cttagcatga tgatttccta cttcttacta
    24241 gtaacaactt tcttattgaa gcgcagggat atcattacca agaagtttat ggggtggaaa
    24301 ctggtcgatc gctaccgtcc tctcctcgtt ctgctcttgc tgggctatag tttccctctt
    24361 ctagtcttga ttttctttgc ccatgcgttc ttaccacttc tactgtttgc aggttttaca
    24421 tgtctggata tactatttgt gctaggctta gcttctagga tggagaaaag aagtctagta
    24481 gagttattga aagggggcat cttatgattg agttgaaaaa tattaccaaa accattgggg
    24541 gaaaagtgat tttggataac ttatctctca ggattgatca gggggatttg gtagctattg
    24601 ttggtaagag tggtagtggg aagtcgacct tgttaaattt attgggtttg atagatggtg
    24661 attatagcgg acggtatgag atttttggtc agacaaatct agcggttaat tctgctaagt
    24721 cgcaaacaat aatccgtgaa catatctctt atctgtttca aaattttgcc ctgattgatg
    24781 atgaaacggt cgagtacaat ctcatgctgg cgctgaaata tgtgaaattg cctaagaaag
    24841 acaagctcaa aaaggtggaa gagattttag agagagtagg tttgtcagct actttgcatc
    24901 aaagggtctc cgagttgtct gggggcgaac aacaacgaat tgcagttgct agagccatct
    24961 taaaacccag ccagctgatt ttagccgatg aacctacagg ttcgctggat cctgaaaata
    25021 gagatttggt cttgaagttt ctcttagaga tgaatcgaga ggggaaaaca gtcattatcg
    25081 tgacccacga tgcttatgta gcccaacaat gtcatcgaat cattgaatta ggcgagggaa
    25141 aatgagttcg ttcagcttca tttgaccgac tgaatactca tatttttcag agagaaatag
    25201 cataaatagg cctaggaatg atatttttat gtcattttcc tgggtttttc tgttttaaat
    25261 tgaaaaaaaa tacaatttag gcttgacaaa ggatgagtat aggagtatta tttatacaat
    25321 aaaaaagaat aaacataaag gaggctttgt tatgaataag atgaagaagg tgttgatgac
    25381 gatgtttggt ttagtgatgc tccccctact atttgcttgt agtaacaatc aatcggctgg
    25441 aattgaagcc atcaagtcca aaggaaaatt ggttgtagcc ctcaatccag attttgctcc
    25501 atttgaatat caaaaagtgg ttgatgggaa aaatcagatt gtgggttcag atatcgaatt
    25561 agccaaggct atcgcaacag aactaggtgt cgaattggaa ctatctccta tgagttttga
    25621 caatgtactg gctagcgttc aatcaggaaa agctgacctt gccatatcag gtgtttctaa
    25681 gacagatgaa cggagcaagg tgtttgattt ttcaactccc tactatactg caaaaaataa
    25741 actcattgtc aaaaaatctg atttagccac ttatcagtct gtcaacgatt tggcgcagaa
    25801 aaaggtcgga gcgcagaaag gttcgattca agagacgatg gcgaaagatt tgctacaaaa
    25861 ttcttccctc gtatctctgc ctaaaaatgg gaatttaatc acagatttaa aatcagggca
    25921 agtggatgcc gttatttttg aagaacccgt tgccaaggga tttgtggaaa ataatcctga
    25981 tttagcaatc gcagacctca attttgaaaa agagcaagat gattcctatg cggtagccat
    26041 gaaaaaagat agcaaggaat tgaaagaggc agtcgataaa accattcaaa agttgaagga
    26101 gtctggggaa ttagacaaac tcattgagga tgcctttaaa gcgtccattg aaaaatagaa
    26161 agaaggaaaa gaacatgagt aaagaaaaag taattttggc ctattctggc ggtttagaca
    26221 catcagttgc tattacctgg ctgaagaaag actatgatgt tgttgcagtt tgtatggatg
    26281 tgggtgaagg gaaagactta gatttcatcc atgataaggc tcttaaggtt ggggcagtcg
    26341 aatcttatgt cattgatgtt aaggacgaat ttgctacaga ttatgtgcta gtagctctcc
    26401 agtcacatgc ctactatgaa caaaagtacc ccttggtatc tgccttgagc cgccctctta
    26461 tttctaaaaa attggttgaa atagcgcatc agacaggagc gactacaatt gctcatggtt
    26521 gtacaggtaa ggggaatgac caagtacgtt ttgaagtatc gattgcagcc ttggatctca
    26581 atttaaaagt gattgctcca gttcgtgaat ggaaatggtc tcgggaggaa gaaatttatt
    26641 atgccaagga aaatggggtg cctgttcctg ctgaccttga caatccctac tctgtcgacc
    26701 aaaatctttg gggacgtgcc aatgagtgtg gtattttgga aaatccatgg aatcaggctc
    26761 cagaagaagc ctttggcatc acaacttctc cagagcaagc tccagatatg ccagaataca
    26821 ttgagattga gtttagtgaa ggtgttccag tttccctcaa tggagaagtg ttaaaattgg
    26881 cagatttgat tcaaaaactc aatgaaatag ctggaaaaca tggggttgga cggattgacc
    26941 acgtggaaaa tcgcttggtt gggattaaat caagagaaat ctatgagtgt ccaggtgcag
    27001 tgaccctgct gacagctcat aaggaaattg aggacttgac gcttgtgaga gaagtggctc
    27061 attttaaacc aatcatagaa aatgaattat caaatctcat ttataatgct ttgtggttta
    27121 gttcggctac acaagccttg attgcttata ttaaagagac tcaaaaagtt gtcaatggga
    27181 ctgcaaaagt caaactgtat aaggggagcg ctcaggtcgt ggctcggaaa tcaccaaatt
    27241 ctctttacga tgaaaatttg gcgacgtata ctagtgcaga taccgttgac caagatgcgg
    27301 ctgttggctt tattaagtta tggggacttc caaccaaggt tcattctgag gttcaaaaaa
    27361 gcgccaaata ggacgattgg atagagaggt ggatgtgata tggctaagaa tacaaaatta
    27421 tggggtggtc gctttggcag gaacgacttt ccccattgat cgccaattgt ctagcgattt
    27481 gctggagttt aagcaacctt atacaaattc tttggatgct gttagtgacc gcgattttat
    27541 cttagaattt ctatcaaatg ccagcatact catgatgcat atgagtcgtt tttgcgaaga
    27601 aatgatcaat tggtgtagtt ttgagtacca attcattacc ttgtcagata cgtttacaac
    27661 aggttcctct attatgcccc aaaagaaaaa tccagatatg gctgagttga ttcgaggaaa
    27721 gactggcaga gtttatgggc atttgtttgg actgttgaca gtcatgaagt ccttgccttt
    27781 agcttataat aaggatttgc aagaagataa ggaaggaatg tttgatacgg tcgaaacgat
    27841 tttaaattcc ctcgatgtgt tggcaggtat gttatctagt ttgcaggtaa acaaggaaaa
    27901 aatgcaagaa tcaacagaga aggacttttc aaatgcaact gagttggcag attatttggc
    27961 agggaaaggc ttgccattta gagaagctca tgaggttgtg ggaagattag tgctagactc
    28021 tatcaagtct gctaaaaatc ttcaagattg gactttggag gaattacaaa cctatcattc
    28081 tctcattacc gaggatatct atgtctactt gcaacctaaa actgctgttc aaagacgaaa
    28141 ttccttggga ggcacagggt ttgaccaagt cgaataccag attgcagtcg ctaagaaagc
    28201 gaatgaagct aaaaagtgat ggagtgatgg gttcagaata agaggttggt cgattggcag
    28261 cctctttctt gtcgttgaaa aagtgagata tattgacttt tgaaaaaaat gtcataattg
    28321 agttgggata aacgtaaaag tcatactttc tcgttaaatc gttcggcgat tcatggtgac
    28381 atggacacat agtagtaaac acactatgtg gcttggcaga gctaaaaact tctggcttaa
    28441 caatggctgg tattaagaac taacgaacaa ataatatgta aagagtcgag gaaatccctc
    28501 ggctttttta tctttccttc gcttggtaat agatctctac ttcttttttg agatgagaca
    28561 gtatagaagt ttcctcggtt agctccagaa gggagaaccc tttttggata agtttcgcat
    28621 catccctaca aatcccaata cggacatagc agatagccag cctatcgtag cttttcttat
    28681 tcttggcgtc ctccagtaaa gtgtagcaga tttgcttaca catgttttta tcttgattgt
    28741 atagatagag tgtggaaagg tttaatagaa ttgtcattcg caagtcatat aaatgttgat
    28801 agtttttata gacttctagg cgttgcaata tttttccagt gatgagatgg aggtattcaa
    28861 tgggaaaact gaaaagaatg gtattgagga tttttagatc actctcatac catgtatctt
    28921 gtttttcaat ttttttccaa agttttttga caacctgttc tgcgtgtttt gatagttccc
    28981 ctgccccgtg ttgacggaga taaataacaa cttcaagcat atctctgatt tcttctatag
    29041 ggagatcgtg gtgggtcttg aggtagtctt ggcatttttg aaataaattg acaagatcgc
    29101 tggtcccgat aatggaacgc atattgagat aggtttgcat aatctctgtg cgttgacttg
    29161 gttgataaag ttgacagata tattcaaact cttcaaaact catattgatt tgacggagaa
    29221 gaaattccat attttcatat tttggggttg tcttgccact ttcgattttt gataagctgg
    29281 ttcttgagag aacaccccca cagacctctt cttgggtcag cccctttgac tcacgtattt
    29341 ctttatagac ctttccgaaa tcataacgca tgattttctc cttttcgtga aaaaagttaa
    29401 caaacaataa aattttgtta aaaatattgt atcatagcaa tgtaaaaagt aaaaaagaaa
    29461 gtcgaaataa atttgtgaaa aaagttaacg taattttaaa atgagcttaa taagaggtac
    29521 tatgtaggta gaaaataaag ataggagaaa aagtatgaat aaaaaaatat tttgtattct
    29581 agtatgtatt atatcattga ttagtctggc tataatcttt ccatggggct ggccgatata
    29641 atgtaaggga gtttgagttg ttaaaggagg ctcagtcctt gggcaaaaat ctgctgtact
    29701 acaatgcttg gaaagatatc aagaacaaag aatgatacgg ttgaaaataa attaattcaa
    29761 gaactactgg gcagtgattg aggtttgggt gacatcaaag aaaagttaga tgaattctaa
    29821 agaattgagt atttctatgt taaaaaaata tccttgtacg atgcaacatg accagtcaga
    29881 ttgtgctgcg gcagttgttt caacagttct tttatcttac aaaaaggaac tatcaatcat
    29941 gaagattagg gaaattattg gtacagacat gtatggaacg actgtcagtg gtattgtttc
    30001 aggtctgaat aagttgaatt ttacagtaaa agctgttcga gtagcactgg aagatttgac
    30061 tccaaaatta acatttcctg cgattcttca agttaagaat gatttaggtc aaaatcattt
    30121 tgtggtatta catagtatca aaaggaatag taaattttac gtagcagacc ctgctagtgg
    30181 catacgcaag atgtcaagtg atgaactggg agaaatttat caaggtatta ctctttttat
    30241 ggttccaaat tcggattttg aaagagggaa actaaaggga aaaggacttc ttgatttatt
    30301 tggaaggtta atttttaatc aaaaaggatt gattagtaca gtcatattag cttcctttgt
    30361 tttaagtatc attggtattt tatcgagtct cttttcaaaa gttatcatgg acgaggtgat
    30421 tccatatgct ttaaaaaata gtctgtatat gtttttgata gtatttggaa tagtgtcgtt
    30481 cttacagact cttctatctg catttcgtca gcacgttctt ttgtttctat ctcgaaaaat
    30541 tgatataccg gttttaatgg gatattatga ccatattatt catcttcctt atagtttttt
    30601 tggaagtcgt agagttggtg atgttttaac aagatttcaa gatgcgatga cgataaagaa
    30661 tgtgtttacg tcagtctcta tttcattagt catggatatc atcttgtcag ttattagtgc
    30721 ggttgtcctt tggactatta atcaatcttt atttctgata ttagttttta tggttattgt
    30781 taacatcatt cttatatact gttttaaaaa gccttataaa aaaattaatc atgaacaaat
    30841 ggaagcaaat ggacttctta attcacagtt aattgaatct attcgtaaca ttgataccat
    30901 taagtctcag catgatgagg aacaacgttt aaacaaaatt gaagaaaaat ttgttcatac
    30961 tttagaaatt ggttataaag agggcgtttt gcagaatatt caatctacaa tatcttcaat
    31021 gacctcaacc atgggtgggt tattatttat gggagtgggc gccttattta tcattgatgg
    31081 aaaaatgact attggggacc tcttggtttt tcagacatta agtcaatatt ttacagaacc
    31141 tattcagaat ttagttggct tgcagttaac ctttcaagag gtacaggttg cggttagtcg
    31201 gcttcaagaa ttgatggaag tagatcgtga agacattgcc ttggattata gtattagaga
    31261 cttcacctta tgtgatgaca ttgaatttaa agatgtaaca tttgcctatg gttcacgccc
    31321 tcctgttatc aaggacttta atttgcgaat taaacaagga gaaaaaatag cttttgttgg
    31381 agaaagcgga gcaggaaaaa gtacgctagt tcgtttgtta ttaagattta taaatccgag
    31441 tgaggggaaa attcgtatag gagaaaatga cttatcagat cttgactatg gtaaactacg
    31501 taagaaaatt tcctacattc ctcagaccat agaactcttt acagggacaa ttattgataa
    31561 tctaaaaatt ggtaatcctt ctgttacata tgaggatatg gtgagagttt gtcgtattgt
    31621 tggtattcat gatacgattc aacgtcttca aaatcgttat ggctcctttg tagaagaagg
    31681 cggtcaaaat ttctcgggtg gagagaaaca acgattggct attgcaagag cactactgag
    31741 taaagctgat ttgtatatat ttgatgaggc aacctctaac ttagattcat ttagtgaaca
    31801 gattattcag gatttaatct ttaataaaat aatagataag acaacaattg tagtagccca
    31861 caggctgtct acaattcttc gatgtgataa gatatgcttt ttagaaaatg ggactattgt
    31921 ggaatatggg actcatgaag aactaatggc gaaaaatgga aagtatgcta gaatggttgg
    31981 tttgcagagc gttcaagtga atcaacaaat tcagtcacag gctgtgttag atatagagga
    32041 ggttacttat ggctaagtta gaggtaaaag ataataaaaa actggtacta aagtcagtta
    32101 tctgtaaaaa gttacatgat acaaaagtag aagatgtaga tcaggaaatt aataaatttc
    32161 atcaacattt gcagttgtta aaagcacaaa tttttggtcc attaattgta aaaagttgtg
    32221 gtactactat tcatgatgat ggattaataa cgactgattt tgagttttat attcaagctc
    32281 ataatgctca acagtacagt aacatttatg atgtacagga ttctatctct gttccatatt
    32341 gtttatatgt tcgttttgaa gacagtccag agtatctaca gtatgcgtat tctaaattgg
    32401 atctatatgt ctatgaaaat gatattcaaa cggatgggat tgtctataca gtttatgtta
    32461 attcttctcc tgaaaaaatg gtagtagata tttttagacc aattgtaagc ctatgaaatt
    32521 atataataaa tcagaattac gttattctcg tattttcttt gataagagac caccagcttt
    32581 tgcgtttatt ctcattattt caactgctat tatcttaagc ggtgcattgg ttggcgcagc
    32641 ttatataccc aaaaactata ttgtaaaagc gaatggaaat tcagttataa caggtacaga
    32701 gttcctatca gcaattggtt cagggaaggt agttacttta cataagtcag aaggagatat
    32761 ggtaaatgct ggagatgtca ttatttcgtt atcaagtgga caagaaggtt tacaagcgag
    32821 ctctttaaat aaacaattgg agaagttacg tgcaaaagaa gctatctttc aaaaatttga
    32881 acaatcatta aatgagaaat acaatcattt atctaattct ggtgaagaac aggaatatta
    32941 tgggaaagtt gaatactatc tgtctcagtt aaactcggaa aattataata atggtaccca
    33001 gtattcaaag attcaggatg aatatacgaa gttgaataaa ataacagctg aaagaaatca
    33061 gttagatgcc gacttgcaag ctctacaaaa tgaattgctt caacttcaac agcaaggaga
    33121 ctcaccttct ttatcagata cgacatcagc tgatgataaa gctaagttag aaactaagat
    33181 atcagaaata acaacaaaaa tcgaagcatt aaaaacaaat attacttcta agaatagcga
    33241 gattgatagt caacaaagca atattaagga tatgaaccgt acctataata atccaacttc
    33301 tcaggcttat aatatttatg ctcaattaat tagtgagtta ggtactgctc gttcaaacaa
    33361 caataaaagt attacagagc ttgaggctaa tcttggagtg gcaacaggtc aagataaagc
    33421 acatagtata ttagcgccaa atgaaggtac tctgcattat ctggtacctt tgaaacaagg
    33481 aatgtctatt cagcaggggc aaacgatagc agaagtttca gggaaagaaa aaggttacta
    33541 tgtagaagct tttgtacttg cgagtgatat ttctcgtgtt tcgaaaggag caaaagctga
    33601 tgttgctatt actggtgtaa atagtcaaaa atatggaaca ctaaagggac aagtcagaca
    33661 gattgattca ggaacaattt cccaagaaac gaaagagggg aatattagcc tctataaagt
    33721 catgatagaa ttagaaacct taactctaaa acatggaagt gagacagtcg tcctccaaaa
    33781 ggatatgcca gttgaagtgc ggattgtcta tgataaagaa acctatcttg attggatttt
    33841 agaaatgtta agtttcaagc aataattggt tttaaacccc ttaggtaacc tataaaaata
    33901 aataaggtag agaaaggata tcttatctag gtagctaagt gatagaaaca cagtcgacga
    33961 ttacttgtta ggaaactatc ctaaccatgc ttaataaaaa aggagaaaat aaatggaact
    34021 catattgcca aataattatg ttgatcttga acaagaagag atgatgtatc ttgatggcgg
    34081 agaaccaatg tcaatttcgg ccattgttgc cttggctatc acaattggtg gcgcatcgta
    34141 tagcacagga tatgtgttag gagaaagagt ctactattca ggatataaaa actctgatta
    34201 tcaaaaaaat aagtggggta ttaggggagc aatgctggct gcatttggag caataggtgc
    34261 agtagttatg ctcggttttg aaaatagata ctatgctttg gttactggta gaggataaaa
    34321 tgttaagagt aatagtagtt attcaatctt tagtaataat actgcttgct gttgctttat
    34381 tattatctcg gaaaaacttt gattcgttaa atgttgttct tataatgatg atcgtatcac
    34441 aattgttgtt attagtatat ttgataaaat tagggaatca gtgattagct gttatttgaa
    34501 ttaagtaaac tgttaagctt caagcagtaa ctggttttaa atatttaaaa taagataaag
    34561 gaaggaagtc taatttaggt aactaaacaa agcctgcgat cacttgttag gaaactatcc
    34621 taaccatgct taataaaaaa ggagaaaata aatggaactc gtattaccaa ataattatgt
    34681 tgctcttgag caagaagaga tgatgtatct tgatggggga gcttatttaa gcaagcgtgc
    34741 ttgtcaagga atttgcgcag ctttagctat gagtccagga acttttatag cattagctgg
    34801 agctgcagtt ttaaccaaaa aactaataaa ctatattaaa gttggaggcc ttggaggttg
    34861 gcttattggt gcagcagcag gtgtattggc tggggcggca ggaagaatag cttactgtat
    34921 tggatatggt gctcttaata gaggttgtga tattagcggg aacccttatc cttgggatgg
    34981 attcatatct gcgacagtaa gatgagtaat gtagataaga ttcgaaaaat acacattatc
    35041 gtatgttgga tgtatatatt tttatcattc agggcgatta taaatgacac ggagtatttt
    35101 ttgcttattt ttttagcttt tatctactca atagtatcac tacctctata ttctgtgaaa
    35161 aataaaatag tatctatctg tctagccata aattcgattc tgttaatgag tttccccatt
    35221 ttaatcaa
//
LOCUS       DBEROT010000020        35128 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.20, whole genome shotgun sequence.
ACCESSION   DBEROT010000020 DBEROT010000000
VERSION     DBEROT010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35128
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.20"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            145..6846
                     /gene="bgaA"
                     /locus_tag="ACL8CG_001141"
     CDS             145..6846
                     /gene="bgaA"
                     /locus_tag="ACL8CG_001141"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGS1343741.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDTKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKTLRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGQTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7094..7540)
                     /locus_tag="ACL8CG_001142"
     CDS             complement(7094..7540)
                     /locus_tag="ACL8CG_001142"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1343742.1"
                     /translation="MFDKEQKRGYKQSAKNLANWHYNDKEDSYIHPDGWCYRFHHIKY
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQDRQIFAQRKI
                     DVEPVFGQIKACLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(7705..7950)
                     /locus_tag="ACL8CG_001143"
     CDS             complement(7705..7950)
                     /locus_tag="ACL8CG_001143"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1343743.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEERHFYTS
                     YHAFGRPSYHPKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(8161..8520)
                     /locus_tag="ACL8CG_001144"
     CDS             complement(8161..8520)
                     /locus_tag="ACL8CG_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGS1343744.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            8612..9568
                     /locus_tag="ACL8CG_001145"
                     /pseudo
     CDS             8612..9568
                     /locus_tag="ACL8CG_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9552..10109
                     /locus_tag="ACL8CG_001146"
     CDS             9552..10109
                     /locus_tag="ACL8CG_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1343745.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALKKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSI
                     ITRPQTTIEALGKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10102..10356
                     /locus_tag="ACL8CG_001147"
     CDS             10102..10356
                     /locus_tag="ACL8CG_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343746.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKDQKEIFESCCKKD"
     gene            10368..12422
                     /locus_tag="ACL8CG_001148"
     CDS             10368..12422
                     /locus_tag="ACL8CG_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGS1343747.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12601..13461
                     /locus_tag="ACL8CG_001149"
     CDS             12601..13461
                     /locus_tag="ACL8CG_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGS1343748.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSINFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQFLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13672..14382
                     /gene="ccdA2"
                     /locus_tag="ACL8CG_001150"
     CDS             13672..14382
                     /gene="ccdA2"
                     /locus_tag="ACL8CG_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS1343749.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14402..14968
                     /locus_tag="ACL8CG_001151"
     CDS             14402..14968
                     /locus_tag="ACL8CG_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGS1343750.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14979..16091
                     /gene="msrB"
                     /locus_tag="ACL8CG_001152"
     CDS             14979..16091
                     /gene="msrB"
                     /locus_tag="ACL8CG_001152"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS1343751.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            16314..17051
                     /locus_tag="ACL8CG_001153"
     CDS             16314..17051
                     /locus_tag="ACL8CG_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1343752.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            17048..18739
                     /locus_tag="ACL8CG_001154"
     CDS             17048..18739
                     /locus_tag="ACL8CG_001154"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1343753.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDARGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VTFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPPKGTKVEIYINRIETS"
     gene            18855..19418
                     /locus_tag="ACL8CG_001155"
     CDS             18855..19418
                     /locus_tag="ACL8CG_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGS1343754.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            19440..25109
                     /gene="zmpB"
                     /locus_tag="ACL8CG_001156"
     CDS             19440..25109
                     /gene="zmpB"
                     /locus_tag="ACL8CG_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease B"
                     /protein_id="HGS1343755.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQLSDKSAEES
                     KVEQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDK
                     SELNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAI
                     DALNVDKSELQEQLRVAEQKQQADYSAKTWREFKIAELQAKEINNPTTPLPKQSEIDA
                     ATKALQDALQALAVDKTVLQNAINTANSKREEEYTAQTWKALKDALTAVNPVNEDETA
                     TQSKVDEATRNLEEAINNLVLLTEKPVLTFIETDKKALEREVVAKYSLENQNKTKIKS
                     ITATLKKGETVVSTVELIGDDVTNETITSAFKNLEYYKEYTLSTTMVYDRGDGDVTEI
                     LDNQPIQLDLKKVELKNIKRTDLIKYENGKETNESLITTVPDDKRNYYLKITSKNQKT
                     TLLAVKNIEETTVNGTPVYKVTAIADNLVSRTADNKFEEEYVHYIEKPKVHEDNVYYN
                     FKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKEFTGKLLSSEGKQFAITELEH
                     PLFNVITNATINNVNFENVEIERSGQDNIASLANTMKGSSVITNVKITGTLSGRNNVA
                     GFVNNMNDGTRIENVAFFGKLHSTSGNGSHTGGIAGTNYRGIVRKAYVDATITGNKTR
                     ASLLVPKVDYGLTLDHLIGTKALLTESVVKGKIDVSNPVEVGAIASKTWPVGTVSNSV
                     SYAKIIRGEELFGSNDVDDSDYASAHIKDLYAVEGYSSGNRSFRKSKTFTKLTKEQAD
                     AKVTTFNITADKLESDLSPLAKLNEEKAYSSIQDYNAEYNQAYKNLEKLIPFYNKDYI
                     VYQGNKLNKEHHLNTKEVLSVTAMNNNEFITNLDEANKIIVHYADGTKDYFNLSSSSE
                     GLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILESVELQSQTMYQHLNRLGDYR
                     VNAIKDLYLEESFTDVKENLTNLITKLVQNEEHQLNDSPAARQMIRDKVEKNKAALLL
                     GLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGSKENNIKGSRTFDAF
                     GQVLAKYTKSGNLDAFLNYNRQLFTNIDNMNDWFIDATEDHVYIAERASEVEEIKNSK
                     HRAFDNLKRSHLRNTILPLLNIDKAHLYLISNYNAIAFGSAERLGKKSLEDIKDIVNK
                     AADGYRNYYDFWYRLASDNVKQRLLRDAVIPIWEGYNAPGGWVEKYGRYNTDKVYTPL
                     REFFGPMDKYYNYNGTGAYAAIYPNSDDIRTDVKYVHLEMVGEYGISVYTHETTHVND
                     RAIYLGGFGHREGTDAEAYAQGMLQTPVTGSGFDEFGSLGINMVFKRKNDGNQWYITD
                     PKTLKTREDINRYMKGYNDTLTLLDEIEAESVISQQNKDLNSAWFKKIDREYRDNNKL
                     NQWDKIRNLSQEEKNELNIQSVNDLVDQQLMTNRNPGNGIYKPEAISYNDQSPYVGVR
                     MMTGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYENGFLGYASNKYKQQSKTDGESVLS
                     DEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSSVSSYDDLLTLFKEA
                     VKKDAETLKQEANGNKTVSMNNTVKLKEAVYKKLLQQTDSFKTSIFK"
     gene            25170..26891
                     /gene="pabB"
                     /locus_tag="ACL8CG_001157"
     CDS             25170..26891
                     /gene="pabB"
                     /locus_tag="ACL8CG_001157"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGS1343756.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADFLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELILEEN"
     gene            26892..27509
                     /locus_tag="ACL8CG_001158"
     CDS             26892..27509
                     /locus_tag="ACL8CG_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1343757.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            27559..28317
                     /locus_tag="ACL8CG_001159"
     CDS             27559..28317
                     /locus_tag="ACL8CG_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGS1343758.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAYSTWQGN
                     YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNS
                     LFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            28444..29403
                     /locus_tag="ACL8CG_001160"
     CDS             28444..29403
                     /locus_tag="ACL8CG_001160"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGS1343759.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGNNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            29500..30339
                     /locus_tag="ACL8CG_001161"
     CDS             29500..30339
                     /locus_tag="ACL8CG_001161"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGS1343760.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(30387..30557)
                     /locus_tag="ACL8CG_001162"
     CDS             complement(30387..30557)
                     /locus_tag="ACL8CG_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGS1343761.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            30678..31562
                     /gene="miaA"
                     /locus_tag="ACL8CG_001163"
     CDS             30678..31562
                     /gene="miaA"
                     /locus_tag="ACL8CG_001163"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGS1343762.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            31555..32793
                     /gene="hflX"
                     /locus_tag="ACL8CG_001164"
     CDS             31555..32793
                     /gene="hflX"
                     /locus_tag="ACL8CG_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGS1343763.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     NYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            32786..33409
                     /locus_tag="ACL8CG_001165"
     CDS             32786..33409
                     /locus_tag="ACL8CG_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGS1343764.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            33424..34353
                     /gene="rnz"
                     /locus_tag="ACL8CG_001166"
     CDS             33424..34353
                     /gene="rnz"
                     /locus_tag="ACL8CG_001166"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGS1343765.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            34374..>35128
                     /locus_tag="ACL8CG_001167"
     CDS             34374..>35128
                     /locus_tag="ACL8CG_001167"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1343766.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLVGETFNYK"
BASE COUNT        10936 a         6513 c         7724 g         9955 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgctgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caagcttcaa gtcaagaaaa accgctcaag
      541 gaagatacta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ctttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgcagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatacgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cttttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttt tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaaaccctt
     2041 agagctaagc atcccaaatg gttgatttat ggatcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt cagattatgg aaatgatcgt gttggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagtcaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt gttcttgaat ggaaaatctc ttggtcttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcagacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattccttga agaagcgcca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgat aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagtgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtcca
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaagg tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag actcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgtcc tattcggaga ttcaggtatt
     4741 ttgagcaaac gttcagttga taacttaagc gttggcttcc atgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtga gagcagacaa caaactagga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa gcaaggacaa
     5101 acaagaatcc aagttgacgg taaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttacg gcagtcacag caagtgttag caacaatggc
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccgg ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaaaac
     5461 ctgacagttg aatgggaaga agttccagcg gaaaatctga taaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgct
     5821 caagccaaac ttcacttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaaccttta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagcagat aagagcggtg ttgcgatgat tgagatgacc
     6121 ttcctggcac cgagtgaatt gcctcaagaa agcacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgaga agacagttgc tgctgtacaa
     6421 gaagatcttc caaaactcga atttgttgaa aaagatttgg cctacaagac agttgagaaa
     6481 aaagattcaa cactgtatct aggtgaaact cgtgtagaac aagaaggaaa aactggtaaa
     6541 gaacgtatct ttacagcgat taatcctgat ggaagtaagg aagaaaaact ccgtgaagtg
     6601 gtagaagctc cgacagaccg catcgtcttg gttggaacca aaccagtagc tcaagaagct
     6661 aaaaaaccac aagtgtcaga aaaagcagat acaaaaccaa ttgattcaag tgaagctagt
     6721 caaactaata aagcccagtt accaaataca ggtagtgcgg caagccaagc agcagtagca
     6781 gcaggtttag ctcttctagg tttgagtgca ggattagtag ttactaaagg taaaaaagaa
     6841 gactagaaat tttgatacct tctttatcat taaagaccaa agaaaaactc ttgtcctaaa
     6901 tagaagataa agagtctgga acaaaatagt tctcaaccac aaaaaagcta gatatttcca
     6961 attgcggaac tctagctttt taattttgag tcgttctctt attgtatagt agattgaaac
     7021 tagagtagta cacttctact tctaaaacat tgttagaaat cgatttgact gtccttatcg
     7081 atttgtcctg ttcttatttc atttcactat gttttaggag gttattggcc ataagtacca
     7141 atcccatgtc aattctcact tgacgcttgc ctctcagatt acatctcttg taacccaaac
     7201 aagcctttat ctgcccaaag acaggttcta catcaatctt gcgttgagcg aaaatctgtc
     7261 tatcttgggg agataaaagc gcctgacatt ctttagcttt caagttttga tagcgttcgt
     7321 tcatatacaa tcccttttga ggggctgatt caggttcatc agcgtagtaa accttgattt
     7381 cctgttgaaa gtctgtctgt gttttctggt acttgatatg gtgaaaacga tagcaccagc
     7441 catcaggatg tatgtagcta tcctccttgt cattatagtg ccaattcgct aagtttttag
     7501 ctgactgttt ataccctctc ttttgttcct tatcaaacat ggcatattta atcagaaggg
     7561 gagtgatttc ttcttgaaaa tagacttgta tctgttcttg aagtttggcg gagaatttct
     7621 ctgtcgtttt cttccacaca aaactatact tgttggcatt ggattcaatc ttagttccgt
     7681 caataaacaa acaatctaag gtcactaact cttccatttt tcaatttttc gaccagagaa
     7741 aatcccttgt gaataggcaa atagaagagt agatacaagc attttagggt gataagacgg
     7801 gcgaccaaag gcatgatagg aggtgtagaa gtgacgttcc tccaaggtat tcaccacttt
     7861 ttcaatagta aagacgagat ggtcttgtgg taagaaggaa ctgatttcta gtggtaaagt
     7921 tgtttgattt gtgttatagt gaatatgcat gggatagcct ttctaaatgg tttattaagc
     7981 aattctattt taccaagact atcgtaacca tgcaaaaaag caacggcaaa tccgttgcct
     8041 tttttggata taagagacta ttgtcccaga ctcttttctt tgtataaaat tgtatagtgt
     8101 tattgtctat actattttgt agagaaagca aaaatcccta gaaaatgctt agggattcga
     8161 ctatttcatt aagaacaatt caacaatcat ctctatatac atgataaggg ttaataaaaa
     8221 tcctgtacgc cagaagaatt tgatgaattt aggatagtaa aagctgcgtt tttttaaaag
     8281 gaagaaaaag acgagaataa tggctaggaa cgagagggct agccccagtc tagggaggaa
     8341 attatgggta aaggttttag ctgtaatcaa gtaatactca aataccaaga ctggaaaagc
     8401 caaatccgca aagtttcgtc ctagtttttt taatctaaaa agtttggtta ggataatgca
     8461 gacgactaag gtcagtatca ataataaaat agatgctaat ttcattaaaa tcatacccat
     8521 attgtatcat aaaaaaaggc taatggaaac gagaaacaga ggaatttata ggaaagtcag
     8581 gcttttgaga ttgtgggtga tttttgttat aatgaaagtt ataaaatctt atgatacctt
     8641 gaatgattat tatcgaaaac tctttggaga aaagactttt aaagtcccta ttgatgcggg
     8701 atttgactgt cccaatcgtg atggaactgt ggctcatgga ggctgtactt tttgtacggt
     8761 ttccggttct ggagatgcca ttgtagcccc agatccgcct atccgtgagc aattttataa
     8821 ggaaattgac tttattcatc gtaagtggcc agatgttcag aagtatctgg tttattttca
     8881 aaattttacc aacacccatg aaaaggtgga agttattcga gagcgttatg aacaggctat
     8941 caatgagcca ggtgtggtag gaatcaatat tggaacgcgc ccagactgtt taccagacga
     9001 aaccatcgaa tatttggctg agttatcgga gtgcatgcat gtgacggttg aattgggctt
     9061 gcagactact tatgaagcaa cctctgacct gattaaccgt gcgcattctt atgaattgta
     9121 ggtggaaacg gtcaagcgtt tgagaaagta tccaaaaatt gagattgttt cccatttgat
     9181 caatggtttg cctggtgaaa cccatgagat gatggttgaa aatgtccgcc gttgtgtcac
     9241 ggataacgat attcaaggga ttaaactgca tttgctccat cttatgacaa atactcgtat
     9301 gcaacgagat taccatgagg gacgtttaca attgatgagt caggacgaat atgtcagggt
     9361 catctgtgac caactggaaa ttattcccaa acatatcgtc atccatcgaa tcacaggaga
     9421 tgcacctagg gatatgctga ttgggcttat gtggagcctc aataaatggg aagctctcaa
     9481 cagcattgag atggagatgc gacgtcgtgg aagtgttcaa ggatgcaagg ctgtaaaaca
     9541 ggagtttgaa aatgaaaaga ccacttgaga tggcacatga ttttttggct gaggtcgtga
     9601 caaaagagga tgtcgtagtg gatgcgacta tgggaaatgg tcatgacacg ctttttttag
     9661 ccaagctagc caagcaagtc tatgcctttg atattcagaa gcaagccttg aaaaagaccc
     9721 aagagcgttt gcatcaggct ggcttgacaa atgcccagtt aatcttgcaa ggccatgaga
     9781 cactggacca gtttgtgaca aaagctaagg cagggatttt taatctgggc tatttgccgt
     9841 cagctgataa gtctatcatc acccgaccgc agacaacgat tgaggcatta ggaaagctat
     9901 gtggcttact tgtcaaaggt ggacgaattg ctattatgat ttactatggt catgaaggag
     9961 gcgacctcga gagagatgct gtcttggatt ttgtaatcca gttgaaccaa caagagtaca
    10021 cagctgccat ttaccgaact ttaaaccaag tcaacaaccc gccgttttta gtgatgattg
    10081 aaaaattaga gagatacaga catggataaa caatacctac acgaaaagct ggatgccatg
    10141 cgccagaatt ttgttgaatc aacccaccac gaacgatcgg tgggcgtgct agaccaagca
    10201 catatgagca aaaaaatgct taaaatcaag aaaaaattag ttgctcttga aatggaacgg
    10261 tgccagagaa aaattgagca caaagactgt tccaagattg accaaaaaat caaagatcag
    10321 aaggagatat ttgaatcctg ttgtaaaaaa gattaaggag gacgtgcgtg gaattactga
    10381 tttacctcat cctattttta ctggttttga ttgtctcaag tacaaccaat aagctcctgc
    10441 cctttttgcc tctccctttg gtgcagattc ttttgggaat tgtgattggt ctctttttac
    10501 ccaatactga ctttcacctt aatacggagt tgtttttggc actggttatc ggacccttgc
    10561 ttttccgaga ggctgaagaa gcagatgtta cggctatttt aaaacactgg cgaatcattg
    10621 tttatctcat atttccagtg atttttatct cgaccctgag tttgggtggc ttggcccatc
    10681 ttctttggtt cagccttccc ttggcagctt gcttggctgt tggggcagcc cttggtccta
    10741 cggacttggt ggcctttgcc tctctttcgg agcgttttag ctttcctaag cgcgtgtcca
    10801 atattcttaa gggcgaagga ctcttgaatg atgcttctgg tttggtggct tttcaggtag
    10861 ctttgacagc ttggacaact ggagcttttt ctctggggca agctagcagt tcgctcatct
    10921 tttcaatcct aggcggtttt ttaattggat ttttaacagc catgaccaac cgcttcctcc
    10981 ataccttctt gctaagtgtg cgcgcaacgg atattgccag tgaactttta ttagaattga
    11041 gtttgcctct agtgaccttc tttctggcag aagaagttca tgtttcaggt attattgccg
    11101 tcgtagttgc tggaatttta aaggcaagtc gcttcaagaa aatcacgctc ctcgaagccc
    11161 aagtggatac ggtgaccgag acggtctggc atacagtgac ctttatgctc aacggttctg
    11221 tctttgtgat tttagggatg gagctggaaa tgatagcaga acctatcttg accaatccaa
    11281 tctataatcc tctactttta ttgctatctc ttatcgccct tacctttgtc ctctttgtca
    11341 ttcgttttat tatgatctat ggctattatg cctatagaac ccgacgcctc aagaaaaagc
    11401 taaataagta tatgaaggac atgtttctct tgaccttttc aggtgttaag ggaacggtgt
    11461 cgattgctac gattctcttg ataccaagta atctagaaca ggagtatcct ctcttgcttt
    11521 tccttgttgc aggtgtgacg cttgttagct ttttaacagg tctcttggtc ttgcctcatc
    11581 tttctgatga agaggaagaa agcaaggatt atctcatgca tatcgccatt ttgaatgaag
    11641 taacgctaga gttggaaaaa gagttggaag acaccagaaa taaactttcc ctttatgcgg
    11701 ctattgacaa ttatcatgga cgtattgaaa atcttatttt aagccaagaa aaccaggatg
    11761 atcaagaaga ctgggctgct ttgaaactct tgattcttag tattgaaagt gatggtttgg
    11821 aacaggccta tgaagagggg aacattagca atcgtgctta ccgagtttac caacgttatc
    11881 tgaaaaatat agaacaagga atcaatcgta aacttgcctc aagactgacc tattattttc
    11941 ttgtttcctt gaggatttta cgttttctcc ttcatgaagt ttttactctc ggaaagacct
    12001 tccgtagctg gaagaacaag gagcaaagcc gtctccgtgc tcttgattat gaccaaattg
    12061 cagagctcta tcttgccaat acagagatga ttattgaaag tttggaaaac ctgaagggag
    12121 tctacagacg ctctttgatt agttttatgc aggagtctcg tcttcgagaa acagctatta
    12181 tcagcagtgg tgcctttgtc gaacgggtta tcaatcgtgt caaacccaac aatatcgatg
    12241 aaatgctaag aggctattat ctggagcgca agttgatttt cgaatacgaa gaaaaacgat
    12301 tgattacaac taagtatgcc aagaaattac gacaaaatgt aaataactta gagaactatt
    12361 ccttgaagga agctgccaat accctgccgt atgatatggt ggaattggta agaagaaatt
    12421 agttaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtatgt
    12481 gactgacttc gtcagtctta tctacaacct caaaacagtg ttttgagcag cttgcggcta
    12541 gctttctagt ttgctctttg attttcattg agtataagat tataaatgaa ggagtatgac
    12601 atgaaaaagt ggtggaaaga gctgatagac aagcctttat taaaagcttt tttgcattat
    12661 tatcaagcat cagatagtga gttgaccagt gtcgcagtag cctactattg gttgatttcg
    12721 attttccccc tgcttttggt ggtggtcaat atcctcccct attttcagat tcctgtggga
    12781 gaatttctgg gctttatgaa agacgtcctg cccccaagcc tctatgaagg tgtggaaaaa
    12841 atagccagag aagtcttgac gcaaccttca acaggtttat tgagtttttc tgttttatcg
    12901 gcgttatgga gtttttcaaa atctataaat ttcttgcaaa aagcttttaa caaggcttat
    12961 ggcgtcgaaa agagtcgtgg acttatttcc catcagatgc taagtctcct agtcagtttt
    13021 ggcttgcagt tcctctttgc gtttgccttg tttttgatct tatttggtca gatgattttg
    13081 gctttacttg ctcattattg gacaaaagat ggcattatct atcaggcttt acaagggttg
    13141 gcaggtcctc tgatttacgc cctcctcttt gctatcttgg tcatgcttta ttattttctt
    13201 cccaatctat ctaacaggaa aattagctat accctaccag gcagtgcctt tgttctctta
    13261 gtgattttag gtttactaac tctgttctct agttatctca attactatgt ccatcatttg
    13321 gtggatgtcc gaattttagg ttccgttctt cttgttgtta tgatgttttg gtttatcttg
    13381 attgctaaaa ttgttatcct aggcgcggtt atcaatgcca gtatgcagag tttgaaagat
    13441 ccggtcttta aaaaagacta actatttatc cattacaaaa gcgcatagta tcaaaacttt
    13501 atagaacctt gatactatgc gcttttgtgc tttgacagtt ttttgtatag tttttgtcca
    13561 agatttctaa atcatctgat taaattccta ttttccccta tcattgtccc tgttttttcg
    13621 aaaatggaag gagtataata aatctatcaa taaaatgata ggaggaactt tatgggtcat
    13681 attttctttt ttctaagtgt ctttttggca gggattctat ccttcttttc tccttgtatc
    13741 ttacctttgt taccggtcta tacaggagtg ttactagatg ataaggatgg tgctcaggct
    13801 tctagcggca aattttcaat ctcagttact agtttattac gaactctggc ctttatagca
    13861 ggaatttcct ttatatttat tttgttgggc tatggagctg gttttttagg cgatttgctt
    13921 tatgcttctt ggttccaata tcttactggg gcaattatta tccttcttgg tttgcaccaa
    13981 atggagattc tacactttaa ggggctttat aaggaaaaga ggctacaact gcaaggacag
    14041 gggcaaaatg gtaagggcta tagtcaggca tttttattgg gcttgacctt tagttttgct
    14101 tggacgcctt gcgtggggcc ggttctgggg tctgttttgg ccttggcggc ttcaggtggt
    14161 tcaggagctt ggcagggagc tggtctcatg ttggtgtata cgctgggctt ggcgctacca
    14221 ttcttgcttc tagctctgac ctctagttat gttttgaaac atttccgaaa acttcatccc
    14281 tatctcggaa tcctcaaaaa agtgggtggt tttctcatta ttgtgatggg actcttggtt
    14341 ctgtttggaa atgcttcaat tttaagtcaa ttatttgaat aaaatggaaa ggaatatcaa
    14401 tatgaaaaaa tggcaaacat gtgttcttgg agcaggttcg ctcctttgtt tgacggcttg
    14461 ttcaggcaag tccgtgacta gtgaacacca aacgaaagat gaaatgaaga cggagcagac
    14521 agctagtaaa acaagcgcag ctaaagggaa agaggtggct gattttgaat tgatgggagt
    14581 agatggcaag acctaccgtt tatctgatta caagggcaag aaagtctatc tcaaattctg
    14641 ggcttcttgg tgttccatct gtctggctag tcttccagat acggatgaaa ttgctaaaga
    14701 agctggtgat gactatgtgg tcttgacagt agtgtcacca ggacataagg gagagcaatc
    14761 tgaagcggac tttaagaatt ggtataaggg attggattat aaaaatctcc cagtcctagt
    14821 tgacccatca ggcaaacttt tggaaactta tggtgtccgt tcttacccaa cccaagcctt
    14881 tatagacaaa gaaggcaagc tggtcaaaac acatccagga ttcatggaaa aagatgcaat
    14941 tttgcaaact ttgaaggaat tagcctagga ggtgtcttat gaatgataag ttaaaaatct
    15001 tcttgttgct aggagtattt tttctagcca taaccggttt ctatgttcta ttgatacgaa
    15061 atgcagggca gacagatgcc tcgcaaattg aaaaggcggc agttagccaa ggaggaaaag
    15121 cagtgaaaaa aacagaaatt agtaaagacg cagacttgca cgaaatttat ctagctggag
    15181 gttgtttctg gggagtggag gaatatttct cacgcgttcc cggggtgacg gatgccgttt
    15241 caggctatgc aaatggtaga ggagaaacaa ccaagtacga attgattaac caaacaggtc
    15301 atgcagaaac cgtccatgtc acctatgatg ccaagcaaat ttctctcaag gaaatcctgc
    15361 ttcactattt ccgcattatc aatccaacca gcaaaaataa acaaggaaat gatgtgggga
    15421 cccagtaccg tactggtgtt tattacacag atgacaagga tttggaagtg attaaccaag
    15481 tctttgatga ggtggctaag aaatacgatc aacctctagc agttgaaaag gaaaacttga
    15541 agaattttgt ggtggctgag gattaccatc aagactatct caagaaaaat ccaaatggct
    15601 actgccatat caatgttaat caggcggcct atcctgtcat tgatgccagc aaatatccaa
    15661 aaccaagtga tgaggaattg aaaaagaccc tgtcacctga ggagtatgca gttacccagg
    15721 aaaatcaaac agaacgagct ttctcaaacc gttactggga taaatttgaa tccggtatct
    15781 atgtggatat agcaactggg gaacctctct tttcatcaaa agacaaattt gagtctggtt
    15841 gtggctggcc tagttttacc caacccatca gtccagatgt tgtcacctat aaggaagata
    15901 agtcctacaa tatgacgcgt atggaagtgc ggagccgagt aggagattct caccttgggc
    15961 atgtctttac ggatggtcca caggacaagg gcggcttacg ttactgtatc aatagcctct
    16021 ctatccgctt tattcccaaa gaccaaatgg aagaaaaagg ctacgcttat ttactagatt
    16081 atgttgatta atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg
    16141 tagggttact gactccgtca gttttatcta caacctcaaa gcggtacttt gagaaacctg
    16201 tggctatctt cctagtttac tttttgattt ttattgagta taagaggtct ttcctaagca
    16261 gttagaggag aattttgcta tactgatact agtaagtggt aaaggagcag atcatgacct
    16321 acacaatctt aatcgtagaa gatgaatatc tggtaagaca aggtttgact aaactggtca
    16381 atgtagcagc ctacgatatg gaaatcatcg gtcaggctga aaatggaagg caggcttggg
    16441 aattgatcca aaagcaggtg ccagatatca ttttaaccga tatcaacatg cctcatctaa
    16501 atggcatcca gttggccagt ctggtacgag aaacctatcc tcaggttcat ttggtctttt
    16561 taacaggtta cgatgatttt gattatgcct tgtctgctgt caaactaggt gtggacgact
    16621 acctgctcaa acccttttct cgtcaggata ttgaggaaat gttggggaaa atcaaacaaa
    16681 aactagacaa ggaagagaaa gaagagcagt tacaagattt attgactaat aggtttgaag
    16741 gaaacatggc ccagaaaatc cagtctcatc tggctgatag ccaatttagt ttaaagtctt
    16801 tagccagtga cttaggtttt agtccgacct atctgagttc cttgattaag aaagagttgg
    16861 gcttgccttt tcaggattat ctggtgagag aacgtgttaa acaagccaag ctcttgcttt
    16921 taactacaga tctgaagatt tatgagatcg cagagaaggt tggttttgaa gatatgaact
    16981 attttaccca acgttttaag cagattgcag gtgtgacacc tcgtcagttt aagaagggag
    17041 aagaccgatg aagcgttctt ctcttttagt tagaatggtt atttccatct ttctggtctt
    17101 tctcattctc ctagctctgg ttggaacttt ctactatcaa tcaagttctt cagccattga
    17161 ggccaccatt gagggcaaca gccaaacgac catcagccag actagccact ttattcagtc
    17221 ttatatcaaa aaactagaaa ccacctcgac tggtttgacc cagcagacgg atgttctggc
    17281 ctatgctgag aatcccagtc aagacaaggt cgagggaatc cgagatttgt ttttgaccat
    17341 cttgaagtca gataaggact tgaaaactgt tgtgctggtg accaaatctg gtcaggtcat
    17401 ttctacagat gacagtgtgc agatgaaaac ttcctctgat atgatggctg aggattggta
    17461 ccaaaaggct attcatcagg gagctatgcc tgttttgact ccagctcgta aatcagatag
    17521 tcagtgggtc atttctgtca ctcaagaact tgttgatgca aggggagcca atcttggtgt
    17581 gcttcgtttg gatatttctt atgaaactct ggaagcctat ctcaatcaac tccagttggg
    17641 gcagcagggc tttgccttca ttatcaatga aaaccatgaa tttgtctacc atcctcaaca
    17701 cacagtttat agttcgtcta gcaaaatgga ggctatgaaa ccctacatcg agacaggtca
    17761 gggttatact cctggtcaca aatcctacgt cagtcaagag aagattgcag gaactgattg
    17821 gacggtactt ggcgtgtcat cattggaaaa gttagaccag gttcggagtc agctcttgtg
    17881 gaccttgctt ggggccagtg tcacatctct tcttgtctgt ctctgcttag tgtggttcag
    17941 tcttaaacgc tggattgctc ctttgaagga tttgagagaa accatgttgg aaattgcttc
    18001 tggtgctcaa aatcttcgtg ccaaggaagt tggtgcctat gaactgagag aagtaactcg
    18061 ccaatttaat gccatgttgg atcagattga tcagttgatg gtagctattc gtagccagga
    18121 agaaacgacc cgtcagtacc aacttcaagc cctttcgagc cagattaatc cacatttcct
    18181 ctataacact ttggacacca tcatctggat ggctgaattt catgatagtc agcgagtggt
    18241 gcaggtgacc aagtccttgg caacctattt ccgcttggcg ctcaatcaag gcaaggactt
    18301 gatttgtctc tctgacgaaa tcaatcatgt ccgccagtat ctctttatcc agaaacaacg
    18361 ctatggagat aagctggaat acgaaattaa tgaaaatgtt acctttgata atttagtctt
    18421 acccaagctg gtcctacaac cccttgtaga aaatgctctt taccatggca ttaaggaaaa
    18481 ggaaggtcag ggccatatta aactttctgt ccagaaacag gattcgggat tggtcatccg
    18541 tattgaggat gatggcgttg gcttccaaga tgctggtgat agtagtcaaa gtcaactcaa
    18601 acgtggggga gttggtcttc aaaatgtcga tcaacggctc aaacttcatt ttggagccaa
    18661 ttaccatatg aagattgatt ctagaccccc aaaagggacg aaagttgaaa tatatataaa
    18721 tagaatagaa actagctaac tcccagtcaa ttctgggagt tttatgcgta attgggcaag
    18781 ctttctaggt tgtctatctt gctaaaaaca agaaaaaacg gtatgataga agagtaacaa
    18841 cagaggtaac agagatgaac gagacacaga ttcaaagaga aacacgtcag gtagtggaag
    18901 atgttttaga aaagaccaat ttgaagcagg gggccctttt tgttttaggt ctatcttcta
    18961 gtgaggtgct aggtggtcag attgggaaag aatccagtca agagattggt gagctgatag
    19021 tggagactat cttgggtatt ctaggtagta gaggtatcca tttagcagtt caaggttgtg
    19081 agcatgtcaa tcgggctctc gttgttgaac gtcaggtggc agagcagttt ggtctggaaa
    19141 ttgtcagtgt ccatcctact cttcatgcag gaggttcggg gcagttggca gcctttaagt
    19201 ttatgcagga tccagttgag gttgaattta tcaaggctca tgctggattg gatatcggag
    19261 acactgcaat tggcatgcat gtcaagcatg ttcaggttcc gattcgccct attttgagag
    19321 agattggtca tgcccatgta acggcactgg ctagtcgtcc aaaattaatc ggaggtgcgc
    19381 gtgcgcacta tccgcaagat gctattagga agtcttgaga atgaataaag gagataaaag
    19441 tgtttaaaaa agaccgtttt tcaattcgta agattaaggg agttgtaggc tctgtatttc
    19501 ttggaagcct tttgatggct ccttctgtag tggacgcagc cacctatcac tatgtaaata
    19561 aagagattat ttcacaagaa gctaaagatt taattcagac aggaaagcct gacaggaatg
    19621 aagttgtata tggtttggtg tatcaaaaag atcagttgcc tcaaacaggg acagaagcat
    19681 ctgttttgac agcttttggt ttgctgactg ttgggagctt gcttttaatc tacaagagaa
    19741 agaaaattgc tagcgtcttt ctagttggag ctatgggatt ggtagttctt cctagtgcag
    19801 gggctgtaga cccagttgcg accctagcac tggctagtcg agagggtgtt gttgaaatgg
    19861 agggctatcg ctatgttggt tatctatcag gtgacatcct caaaacgctt ggcttggaca
    19921 ctgttttaga agaaacctca gcaaaacctg gagaggtgac tgtagtcgaa gttgagactc
    19981 ctcaatcaac aacaaatcag gagcaagcta ggacagaaaa ccaagtagta gagacagagg
    20041 aagctccaaa agaagaagca cctaaaacag aagaaagtcc aaaggaagaa ccaaaatcgg
    20101 aggtaaaacc tactgacgac acccttccta aagtagaaga ggggaaagaa gattcagcag
    20161 aaccagctcc agttgaagaa gtaggtggag aagttgagtc aaaatcagag gaaaaagtag
    20221 cagttaagcc agaaagtcaa ctatcagaca aatcagctga ggaatcaaaa gttgaacaag
    20281 taggtgaacc agtcgagcca agtgaagacg aacaggcacc aacggcacca gttgagccag
    20341 aaaagcaacc agaagctcct gaagaagaga aggctgtaga ggaaacaccg aaaccagaag
    20401 ataaaataaa gggtattggt actaaagaac cagttgataa aagtgagtta aataatcaaa
    20461 ttgataaagc tagttcagtt tctcctactg attattctac agcaagttac aatgatcttg
    20521 gacctgtttt agaaactgca aaaggtgtct atgcttcaga gcctgtaaaa cagcctgagg
    20581 taaatagtga gacaaataaa cttaaaacgg ctattgacgc tctaaacgtt gataaaagtg
    20641 aattacagga acaattaaga gttgctgaac aaaaacaaca agctgactat agcgctaaaa
    20701 cttggaggga attcaaaatt gctgaacttc aagctaaaga aatcaacaac ccaactacac
    20761 cacttcctaa acaaagtgaa atagatgcag ctactaaggc tcttcaagac gctcttcaag
    20821 ctcttgctgt agataaaact gtattacaaa acgctattaa cacagctaat agcaaacgtg
    20881 aagaagagta tactgctcag acatggaaag cgttaaaaga tgctcttaca gcagtgaatc
    20941 ctgttaatga agatgaaact gcaactcaaa gcaaagtaga cgaagctact agaaacttag
    21001 aagaagctat caataaccta gttctattaa ctgaaaaacc ggtattaaca tttattgaga
    21061 ctgataagaa agcattagaa cgtgaagtag ttgctaagta ttctctagaa aaccaaaata
    21121 aaacaaaaat taaatcaatc acagctactc tgaaaaaagg agaaacagtt gttagcactg
    21181 tagagcttat aggcgatgat gtaactaatg aaactataac ctctgcattt aagaatctag
    21241 agtactacaa agaatacacc ctatctacaa ctatggttta cgatagaggt gacggtgatg
    21301 taacagaaat cttagataat caaccaatcc aactagatct taaaaaagtt gagcttaaaa
    21361 atattaaacg tacagattta atcaaatacg aaaatggaaa agaaactaat gaatcactaa
    21421 taacaactgt tcctgatgat aagcggaatt attatttaaa aataacttca aagaatcaaa
    21481 aaactacatt actagctgtt aaaaatatag aagaaactac ggttaacgga acacctgtat
    21541 ataaagttac agcaatcgca gacaatttag tctctagaac tgctgataat aaatttgaag
    21601 aagaatacgt tcactatatt gaaaaaccta aagtccacga agataatgta tattataact
    21661 tcaaagaatt agtggaggct attcaaaacg atccttcaaa agaatatcgt ctgggacaat
    21721 caatgagcgc tagaaatgtt gttcctaatg gaaaatcata tatcactaaa gaatttacag
    21781 gaaaactttt aagttctgaa ggaaaacaat ttgctatcac tgagttggaa catccattat
    21841 ttaatgtgat aacaaacgca acgataaata atgtgaattt tgaaaatgta gagatagaac
    21901 gttctggtca agataatatt gcatcattag ccaatactat gaaaggttct tcagttatta
    21961 caaatgtcaa aattacaggc acactttcag gtcgtaataa tgttgctgga tttgtaaata
    22021 atatgaatga tggaactcgt attgaaaatg ttgctttctt tggcaaacta cactctacaa
    22081 gtggaaatgg ctctcataca gggggaattg caggtacaaa ctatagagga attgttagaa
    22141 aagcatatgt tgatgctact attacaggaa acaaaacacg cgccagcttg ttagttccta
    22201 aagtagatta tggattaact ctagaccatc ttattggtac aaaagctctc ctaactgagt
    22261 cggttgtaaa aggtaaaata gatgtttcaa atccagtaga agttggagca atagcaagta
    22321 agacttggcc tgtaggtacg gtaagtaatt ctgtcagcta tgctaagatt atccgtggag
    22381 aggagttatt cggctctaac gacgttgatg attctgatta tgctagtgct catataaaag
    22441 atttatatgc ggtagaggga tattcgtcag gtaatagatc atttaggaaa tctaaaacat
    22501 ttactaaatt aactaaagaa caagctgatg ctaaagttac tactttcaat attactgctg
    22561 ataaattaga aagtgatcta tctcctcttg caaaacttaa tgaagaaaaa gcctattcta
    22621 gtattcaaga ttataacgct gaatataacc aagcctataa aaatcttgaa aaattaatac
    22681 cattctacaa taaagattat attgtatatc aaggtaataa attaaataaa gaacaccatc
    22741 taaatactaa agaagttctt tctgttaccg cgatgaacaa caatgagttt atcacaaacc
    22801 tagatgaagc taataaaatt attgttcact atgcggacgg tacaaaagat tactttaact
    22861 tgtcttctag cagtgaaggt ttaagtaatg taaaagaata tactataact gacttaggaa
    22921 ttaaatatac acctaatatc gttcaaaaag ataacactac tcttgttaat gatataaaat
    22981 ctattttaga atcagtagag cttcagtctc aaacgatgta tcagcatcta aatcgattag
    23041 gtgactatag agttaatgca atcaaagatt tatatttaga agaaagcttc acagatgtta
    23101 aagaaaactt aacaaaccta atcacaaaat tagttcaaaa cgaagaacat caactaaatg
    23161 attctccagc tgctcgtcaa atgattcgtg ataaagtcga gaaaaacaaa gcagctttat
    23221 tactaggttt aacttaccta aatcgttact atggagttaa atttggtgat gttaatatta
    23281 aagaattaat gctattcaaa ccagatttct atggtgaaaa agttagcgta ttagacagat
    23341 taattgaaat cggttctaaa gagaacaaca ttaaaggttc acgtacattc gacgcattcg
    23401 gtcaagtatt ggctaaatat actaaatcag gtaatttaga tgcattttta aattataata
    23461 gacaattgtt cacaaatata gacaatatga acgattggtt tattgatgct acagaagacc
    23521 atgtctacat cgcagaacgc gcttctgagg tcgaagaaat taaaaattct aaacatcgtg
    23581 cattcgataa tttaaaacga agtcacctta gaaatactat actcccacta ctgaatattg
    23641 ataaagcaca tctttattta atttcaaatt ataatgcaat tgcctttggt agtgcagagc
    23701 gattaggtaa aaaatcatta gaagatatta aagatatcgt taacaaagct gcagatggtt
    23761 atagaaacta ttatgatttc tggtatcgtc tagcgtctga taacgttaaa caacgactac
    23821 taagagatgc tgttattcct atttgggaag gttataacgc tcctggtgga tgggttgaaa
    23881 aatatggccg ctataatacc gacaaagtat atactcctct tagagaattc tttggtccta
    23941 tggataagta ttataattat aatggaacag gagcttatgc tgctatatat cctaactctg
    24001 atgatattag aactgatgta aaatatgttc atttagaaat ggttggtgaa tacggtattt
    24061 cagtttacac acatgaaaca acacacgtca acgaccgtgc gatttactta ggtggctttg
    24121 gacaccgtga aggtactgat gctgaagcat atgctcaggg tatgctacaa actcctgtta
    24181 ctggtagtgg atttgatgag tttggttctt taggtattaa tatggtattt aaacgcaaaa
    24241 atgatgggaa tcagtggtat attacagatc caaaaactct aaaaacacga gaagatatta
    24301 atagatatat gaagggttat aatgacactt taactcttct tgatgaaatt gaggctgaat
    24361 ctgtgatttc tcaacaaaat aaagatttaa atagtgcatg gttcaaaaaa atagatagag
    24421 aataccgtga taacaataaa ttaaatcaat gggataaaat tcgaaatcta agtcaagaag
    24481 agaaaaatga attaaatatt caatctgtta atgatttagt tgatcaacaa ttaatgacta
    24541 atcgcaatcc aggtaatggt atctataaac ccgaagcaat tagctataac gatcaatcac
    24601 cttatgtagg tgttagaatg atgaccggta tctacggagg taatactagt aaaggtgctc
    24661 ctggagctgt ttcattcaaa cataatgctt ttagattatg gggttactac ggatacgaaa
    24721 atgggttctt aggttatgct tcaaataaat ataaacaaca atctaaaaca gatggtgagt
    24781 ctgttctaag tgatgaatat attatcaaga aaatatctaa caatacattt aatactattg
    24841 aagaatttaa aaaagcttac ttcaaagaag ttaaagataa agcaacgaaa ggattaacaa
    24901 cattcgaagt aaatggttct tccgtttcat catacgatga tttactgaca ttgtttaaag
    24961 aagctgttaa aaaagatgcc gaaactctta aacaagaagc aaacggtaat aaaacagtat
    25021 ctatgaataa tacagttaaa ttaaaagaag ctgtttataa gaaacttctt caacaaacag
    25081 atagctttaa aacttcaatc tttaaataat tgaaatctct catctgcttt gcggatgagg
    25141 gttttcttat tttatgctat acttaaagta tgcatagaaa aacagtgatt gattttagga
    25201 ctttggggga gagatatacc tttacccagc ctattaaaga gttgaaaacg agaaatgtag
    25261 aagaagtggc agattttctg gcacaagtgg aaagctacca agagcaaggt tattatgtgg
    25321 tggggtatgt cagctacgag gctgcacctg cttttgagga aaaattagca gttcacaagg
    25381 atcccctact gggagagtac ctgctttact ttactgttca tgatagcgta gaaacttccc
    25441 ctattcctct gacttatgag gatattgatt tgccctcaaa ttggcaggaa gtgacgtctg
    25501 cagcagacta tgaaaaggcc attgcccaga tacaccatca cttgaggcag ggagacacct
    25561 atcaggtcaa ctacaccgtc caactcaagc aaaagttaag tgccaatcct tttgccatct
    25621 acaatcgtat ggtggtagag caggaggcgg gctacaatgc ctatgtggaa catgacgaga
    25681 tggcagtgat ttccatgagc ccagagctct tttttgagca aaatgatcgc gagttgacaa
    25741 cacgaccaat gaaggggacg actcagcgtg gggtaactga ccaagaagat cttgaacagg
    25801 ccagttggtt ggaacaggat cccaaaaatc gctctgaaaa tatgatgatt gtggacctct
    25861 tgcgcaatga tatgaaccgt atttctgaag ttgggagcga gcacgtggag cgtctgtgcc
    25921 aggtagagca gtattcaact gtttggcaga tgacttcgac catcaagagt cagttgcgag
    25981 aggatgtgga ccttgttgaa atcttccgct cactctttcc ttgtggttcc ataacgggtg
    26041 caccgaaaat tgcgacaatg gagattatca aggacttgga gcctcaaccg cgtggagtct
    26101 actgtggaac gattggtctc ttgcttccaa atggacgacg gatttttaat gtggccattc
    26161 gtaccattca acttcacaaa ggtcaagcca tttatggagt tggcggaggg attacttggg
    26221 atagcacatg ggaatctgaa taccgagagg ttcatcaaaa ggcagcagtt ctttatcgta
    26281 aacaagctcg cttccaactg attacgacag gggaaatcag ccagaagaac ctgctgtttg
    26341 aagatcaaca tctggaaaga ctgagaaaag ctagtcgtta ttttgctttt ccttttgatg
    26401 cagaagactt gggacacaag attgaggaag agtgtcagga ttgtgaagct aatcgagatt
    26461 accgcttgcg aatcagcctt agcaaatctg gagagataga agtcaatcgt caagtattaa
    26521 cccctctcag tacaagcttt tgtcaggccc aagtctgcct tcaggaagct gctttgaatc
    26581 aatcctttac ctactttaaa accactcacc gaccgcattt gagcctagga gaacaagaga
    26641 agatttacca caataagtca ggagaactgc ttgaaacctc tataggaaat ttggttctga
    26701 aaatcgctgg aaaactctac acaccgccta tccgacttgg aatcttgcca ggaatttacc
    26761 gtcagtattt gctagaaaca ggacaggtag aagagaaagt cttgaccttg gcagatttag
    26821 cccaagcaga agctatttac ggctgtaatg cagtgagagg cttgtatgaa ctaatccttg
    26881 aggagaacta gatgaaactg atatttttgc atgggttagg gcagtcagca gagtcttgga
    26941 aagaagttcg gaatctactg acagattatc cttctgaggc tatcgagtta tttccttctg
    27001 gagttagtaa ctatcaacaa gctaaggagc gagtttatca gcacctagct caagagacag
    27061 aaccttttgt tttgattgga ttgtccttag gtgctgccct ggcactagaa ctttccagtt
    27121 acgatttacc aaatcttcga gctttgattc tgtcaggatg cccgcttaaa ttagcaggga
    27181 atatcctatt ttatcttcag ttgctgattt ttaaactact tcccaaaaga gtatttgaaa
    27241 aacagggagc agacaaggct cttatggtcg gagtttctga ggagttgaag acacttgatt
    27301 taacggatat agcaggaact tgcccttatc caaccttact aatttgtggt atcaaagata
    27361 aaccgaatct tagttctatg agaagtcttc ataaactaat atcagaatcc caatttcaga
    27421 ttatcccaga tggccctcat gtcttgaata aggcaaaacc aaaggagttt gtagaaaaga
    27481 ccagaagttt tcttgaattg ctgaaataag tttgataaaa taatattgaa atcgatatca
    27541 taattatggg agaaagaaat gaataaacgt ctatttttaa aaatgagtct ggtgacgttg
    27601 ccaattttag ccttgttttc acaacctgtg ttagcagagg aaaacattca tttttcgagt
    27661 tgtaaggaag cttgggctaa tggatattcg gatcttcatg agggagaacc tggttattct
    27721 gccaagttag accgcgatca tgatggtgtg gcttgcgaat tgaaaaatgc tcctaagggt
    27781 gcttttaaag caaaacaagc ggctacaact caaactgata caacttcatc cacagcaagt
    27841 ggttgggtta agcaggacgg ttcttggtac tattttgatg gaaatggaaa tctagtgaaa
    27901 aatgcatggc agggaaatta ttacctgaaa gctgatggta aaatggcaca gagtgaatgg
    27961 atttatgact cttcttatca agcttggtat tatttgacat cagatggttc ttatgcttac
    28021 agtacatggc aaggaaatta ctatctaaaa tcggatggta aaatggctgt caatgaatgg
    28081 gttgatggtg gacgttatta tgttggcgct gacggagttt ggaaggaagg tcaagcaagt
    28141 acagcttctt ctagtaatga tagcaatagt gaatattctg ctgctttagg aaaggcaaaa
    28201 agttataatt cgttattcca catgtcaaaa aaacgtatgt atagacaatt aacttctgat
    28261 tttgataaat tttcaaatga tgcagctcaa tatgccattg atcatttaga tgattaacag
    28321 atactggtag gcgaaaaaat tccttataat tcatttacgc aaacctttgc ataagtgaat
    28381 gtattttgat atactagtac tgtaagcatt ttcaattact acacaatgaa aaaggagaat
    28441 atgatgagtc aaaagattat tgggattgac cttggtggaa cttctatcaa atttgcaatc
    28501 ttaacaacag caggagaaat ccaaggaaaa tggtcaatca agaccaacat tttggatgag
    28561 ggaagtcata tcgttgatga tatgattgag tctattcaac atcgtttgga cttgcttgga
    28621 ttggcagcag cggacttcca aggcattgga atgggatcac caggtgtggt tgaccgtgac
    28681 aaagggactg ttatcggtgc ctacaacttg aactggaaaa cccttcaacc aatcaaacaa
    28741 aagattgaaa aagctttggg cattccattt ttcatcgata atgatgccaa cgtagcagct
    28801 cttggtgagc gctggatggg tgctggaaat aaccaaccag acgttgtctt tatgacactc
    28861 ggtactggtg ttggtggtgg tattgtcgca gaaggcaaat tgcttcacgg tgttgctggt
    28921 gcagcaggtg agcttggtca tatcactgtt gattttgacc aaccaattgc atgtacttgt
    28981 ggtaaaaaag gctgccttga gacagttgct tcagcaacag ggattgtcaa cttgactcgt
    29041 cgctatgccg atgaatacga aggcgatgca gccttgaaac gcttgattga taatggagaa
    29101 gaagtaactg ctaagactgt ctttgatctc gcaaaagaag gagacgacct tgctttgatt
    29161 gtttaccgta acttctcacg ttacttggga atcgcttgtg ctaacattgg ttcaatccta
    29221 aacccatcaa caatcgtcat cggtggtggt gtgtcagctg cgggagaatt ccttctacaa
    29281 ggtgttcaaa aagtttacga tgaaaatagt ttcccacaag tacgcacatc tactaaatta
    29341 gctcttgcaa ctctaggaaa tgacgctgga gttatcggag cagcatcact tgtattgcaa
    29401 taagataatg agagaggaaa atgctaacct agagttagta atgttcctct tttatttttt
    29461 atgctatact agttaggaca atgaatgagg tgagagtaaa tgacaaaagc agatacgatt
    29521 tttaaagaga atattgaacg cattctaaag gaaggtgttt tctcagagca ggctcgtcct
    29581 aagtacaagg atgggactgt tgctaattcc aagtatgtaa ctggtgcctt ttccgagtac
    29641 gacttatcta aaggagaatt tcctatcaca accttgcgtc ccattgcaat caaatccgcc
    29701 atcaaagaag ttctctggat ttaccaagac cagtcaaata gcttagaagt gcttaatgac
    29761 aagtacaatg ttcactactg gaatgactgg gaagttggag acacgggaac cattggtgag
    29821 cgctatggtg ccgttgttaa gaaacacgac attatcaata agcttctcaa acagttggaa
    29881 accaatcctt ggaaccgccg caatattatt tcgctctggg attaccaagc tttcgaagaa
    29941 acagatgggc tgctcccgtg cgcctttcag accatgtttg atgtccggcg tgttgatggg
    30001 gaaatctatc tggatgcgac cttgacccag cgctccaatg atatgctggt ggcccaccac
    30061 atcaacgcta tgcagtatgt ggctttgcag atgatgattg ccaaacattt tggctggaag
    30121 gttgggaagt tcttctactt catcaacaac ctccatatct atgataatca atttgaacaa
    30181 gctcaggaat tgctccgtcg ggagccgtca aactgccaac cacgcttggt tttaaatgtt
    30241 cctgatggga ctaatttctt tgatatcaaa gcagaagatt ttgagttggt ggattatgac
    30301 cctgttaagc cacagttgaa gtttgaccta gctatttaaa agaatagaaa aaagaagttg
    30361 agaataatcc caacttcttt tgtttcttaa cgtgatacgc ggcgacgagc tgctttttta
    30421 cggttttctt cgatgaaagc tgctttttgc tcttctggtt cgattacttt ctttttaaat
    30481 gcgtatactg cacctgcaac ggcagcgaca gttcctgcga cacctgttac aagaccttta
    30541 gcgaatcctt tagccatgag tcttcctcct ttatattctc aatcagccag cctcctcaag
    30601 aggtcacatt tttctgactg acctttttgt gttataataa tagtaacgaa aaaatgggaa
    30661 tttttcaagg aaaaaagatg aaaacaaaaa taattgtgat tgttggaccg actgctgttg
    30721 gaaagacggc tctagctatt gaagttgcaa agcgttttaa tggcgaagtg gttagtggag
    30781 atagccagca agtctatcga ggacttgata ttgggacggc caaggctagt ccagaagagc
    30841 aggcagctgt tcctcatcat ttaatcgatg ttagagagat aaccgagtct tactcggctt
    30901 ttgattttgt ttcagaagct aagatgacta ttgaggatat tcacagccgt ggcaagctag
    30961 ccattatcgc cggtgggact ggactttata tccagagctt gctagaaggt taccacctag
    31021 gtggggagac tcctcatgag gagattttag cttatcgagc tagtttggag ccatattcag
    31081 atgaggaatt agcccatttg gtggagcaag caggccttga gattccccag tttaatcgtc
    31141 gtcgtgctat gcgtgcctta gaaattgccc attttggtca ggatttggaa aatcaagaga
    31201 ccttgtatga accgctgatt atctgcttgg atgatgaacg tagtcaactt tatgagcgta
    31261 tcaaccaccg agtggatttg atgtttgagg ctgggctttt ggatgaggcc aagtggctgt
    31321 ttgaccattc ccctaatgta caggctgcta aaggaattgg ctataaggaa ctctttcctt
    31381 atttccgtgg agagcagacc ttggaggaag ctagtgagag tctcaaacag gctactcgtc
    31441 gttttgccaa gcgtcagctg acctggttcc gtaatcgcat gcaggtcacc ttttatcaga
    31501 ttggagaatc tggtgtacaa gaccgcattt taagccagat agaggagttt ttagatgatt
    31561 gaaacggaga aaaaagagga gcgagtcctg ctgattggtg tggaattgca gggtatggac
    31621 agttttgacc tctccatgga agaattggct agtttagcga aaacggcagg ggcagtcgtt
    31681 gtagataact acagacaaaa acgtgaaaaa tatgattcca agaccttcgt cggctctggt
    31741 aagttggaag agattgcgct tatggtggat gcagaagaaa tcactactgt catcgtcaac
    31801 aaccgtctga caccaaggca gaatgtcaat ctagaggaag ttctcggtgt taaggtcatt
    31861 gaccgtatgc agttgatttt ggatatcttt gccatgcggg ctcgaagcca tgaagggaag
    31921 ctccaagtcc acctagccca actcaaatac ctcttgcctc gcttggttgg tcaggggatt
    31981 atgctcagcc gtcaggcagg gggaattggt tcccgtggtc ctggtgaaag ccaactggag
    32041 ctgaaccgtc gtagcgttcg caatcaaatc acggatatcg agcgccagct caaggtggtt
    32101 gagaaaaatc gggcgactgt cagagaaaaa cgtttggagt ctagcacctt taagattggt
    32161 ttgattggtt ataccaatgc tgggaaatca actatcatga acatcttgac cagtaagacc
    32221 cagtatgaag cagatgagct ctttgcgact ctggatgcga caaccaagag tattcatctg
    32281 ggaggcaatc tccaagtaac tttgacagat accgttggct ttatccaaga tttgccgaca
    32341 gagttggtgt ccagtttcaa gtcaaccttg gaagaaagca agcatgtgga ccttctggtt
    32401 catgttatcg atgctagcaa tccttatcac gaggagcatg aaaaaacggt tctctccatc
    32461 atgaaagacc tggacatgga agatattcct cacttgacgc tttataataa agcggatttg
    32521 gtggaggatt tcacgcctac ccaaacgcca tataccctca tttctgccaa gtctgaggac
    32581 agtcgtgaaa acttgcaagc attattgcta gataagatta aggaaatttt tgaagcattt
    32641 accctgcgag tgcctttttc aaagtcctac aagattcatg atttagagag tgttgcaatt
    32701 ctggaagaac gtgattatca ggaagacagc gaagtgatta caggctacat ttccgaaaaa
    32761 aataaatgga ggttagaaga attttatgac tgatattaaa gctttggctc taaagtatgg
    32821 aggttataca agtctggaca aggtctatct ggatcagctt ctagctggta aaacagagca
    32881 ggagcagtta acacttatta cacctccgcc aagtgttgtt aatgcctact ttgcagaact
    32941 ctatcagaaa aagagtcctc aggctgcgac ggattatttt gcagaactca gtcaggaact
    33001 gaatctttac aatactgagc caagtttcac cctagaaaat aagcctttta ttcggcttaa
    33061 tctgtctggt aaatcctttg gtttttgtta tgatagtgac ggccttggtc ggattttctc
    33121 tgaaaatgag gagaaaatct cggatgactt gctctttgaa attgcgcaaa ttttccccca
    33181 tcaattagtc tttgaagagt ctggtaagat ttacatgaag cctgtcgagg acgaggaagt
    33241 tgtcagccta gaaagtctca cagctttgac tgatttggaa agattggctg atggtcgaaa
    33301 acgtctcaaa ggctacagcc aagaggattt attgcaagaa gctgctgctt tttctggcaa
    33361 acgctatttc cgatcggaaa accgcacagc catgttatat attgattaat tagaaagtat
    33421 cgaatggata ttcaattttt aggaacgggg gctggtcagc cctctaaagc tcgcaacgtt
    33481 tcaagtctcg ccctgaaact tttggatgag attaacgaag tttggctctt tgactgtgga
    33541 gaaggtacgc aaaatcgcat tctggaaacc acaattcgac cacgtaagat cagcaaaatc
    33601 tttattaccc atctgcatgg agaccacatt tttggtttgc caggtttcct ttctagccgt
    33661 gcctttcagg ccaatgaaga gcagacagat ttggaaatct acggacctca aggaatcaag
    33721 tcatttgtct taaccagcct tcgtgtgtca ggttctcgtc tgccctaccg cattcatttc
    33781 catgagtttg accaagattc tctgggtaaa attcttgaaa ccgataaatt cactgtgtat
    33841 gcagaggagc tggatcacac tattttctgt gttggctatc gtgtcatgca aaaagatcta
    33901 gaagggacgc tggatgctga aaaactcaag gctgctggtg ttccgttcgg cccgcttttt
    33961 ggtaaaatca aaaacggcca ggatcttgtt ttggaagacg gaactgaaat caaggcagca
    34021 gactatatct cagcgccacg tccaggtaag attatcacta ttttaggaga cactcgaaaa
    34081 acggatgcca gtgtgcgtct ggctgtcaat gcagatgtcc tagttcatga gtccacttat
    34141 ggcaagggtg atgaaaaaat tgctcgtaac catggtcact caactaatat gcaagctgca
    34201 caagtagcgg tagaagcagg tgccaaacgc ctcctactca accatatcag tgcccgtttc
    34261 ctctcaaaag atattagcaa actcaagaaa gacgctgcca caatttttga aaatgtccat
    34321 gtggtcaaag acttggaaga agtggaaatc tagcagtcac agaaaggata agtatgccta
    34381 ctattctcat taccggagct agcggtggtc tagctcaaga aatggtcaaa ctcctgccca
    34441 atgaccaact catcttgctt ggtagaaata aggaaaaatt agcccaactc tacggaaatt
    34501 attcccatgc agaattgatt gaaattgata ttaccgacga ttcagcccta gaagctctgg
    34561 taactgatct ttatctccgc tatggcaaga ttgatgtctt gattaacaac gctggttacg
    34621 ggatttttga gggatttgac cagattgctg ataaagatat tcaccagatg tttgaggtca
    34681 atacctttgc cctgatgaat ctgtctcgtc accttgcggc tcgtatgaag gaaagcagca
    34741 aagggcatat catcaacatc gtcagcatgg caggtctaat agctactggc aagtctagtc
    34801 tttactcagc gaccaagttt gcggctattg gtttttcaaa tgctctgcga ctcgaactta
    34861 tgccctatgg agtctatgtg acaacagtca atccaggtcc aatccgaaca ggattttttg
    34921 accaagctga cccagatgga acttatctta aatcggttga ccgcttcctc ttagaggcag
    34981 atgcagtggc taaaaagatt gtcaagatta taggcaaaaa taaacgagaa ctcaatctcc
    35041 cgattttgtt gaacctagcc cataagtttt atactctctt tcccaagcta gctgataagt
    35101 tggtagggga aacttttaat tataagta
//
LOCUS       DBEROT010000021        34691 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.21, whole genome shotgun sequence.
ACCESSION   DBEROT010000021 DBEROT010000000
VERSION     DBEROT010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.21"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(8..1354)
                     /gene="glnA"
                     /locus_tag="ACL8CG_001168"
     CDS             complement(8..1354)
                     /gene="glnA"
                     /locus_tag="ACL8CG_001168"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGS1343767.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(1391..1747)
                     /gene="glnR"
                     /locus_tag="ACL8CG_001169"
     CDS             complement(1391..1747)
                     /gene="glnR"
                     /locus_tag="ACL8CG_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGS1343768.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(1824..2351)
                     /locus_tag="ACL8CG_001170"
     CDS             complement(1824..2351)
                     /locus_tag="ACL8CG_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS1343769.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(2487..3683)
                     /gene="pgk"
                     /locus_tag="ACL8CG_001171"
     CDS             complement(2487..3683)
                     /gene="pgk"
                     /locus_tag="ACL8CG_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGS1343770.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINVLEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(3773..8713)
                     /locus_tag="ACL8CG_001172"
     CDS             complement(3773..8713)
                     /locus_tag="ACL8CG_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGS1343771.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     ASEAVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTVQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTSDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFSDVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGKDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGH
                     EVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNT
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            9002..10633
                     /locus_tag="ACL8CG_001173"
     CDS             9002..10633
                     /locus_tag="ACL8CG_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGS1343772.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGDLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFETTL
                     NLAPEMTIAFAHGTFNITNTIIQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11192..12799)
                     /locus_tag="ACL8CG_001174"
     CDS             complement(11192..12799)
                     /locus_tag="ACL8CG_001174"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGS1343773.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYIAFVTAAVENSN"
     gene            complement(13189..13776)
                     /gene="rpoE"
                     /locus_tag="ACL8CG_001175"
     CDS             complement(13189..13776)
                     /gene="rpoE"
                     /locus_tag="ACL8CG_001175"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGS1343774.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(13904..14352)
                     /locus_tag="ACL8CG_001176"
                     /pseudo
     CDS             complement(13904..14352)
                     /locus_tag="ACL8CG_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(14357..14746)
                     /locus_tag="ACL8CG_001177"
     CDS             complement(14357..14746)
                     /locus_tag="ACL8CG_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGS1343775.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHFYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(14773..15423)
                     /locus_tag="ACL8CG_001178"
     CDS             complement(14773..15423)
                     /locus_tag="ACL8CG_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS1343776.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(15413..15976)
                     /locus_tag="ACL8CG_001179"
     CDS             complement(15413..15976)
                     /locus_tag="ACL8CG_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1343777.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGFSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16141..16375)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16429..16932)
                     /locus_tag="ACL8CG_001180"
     CDS             complement(16429..16932)
                     /locus_tag="ACL8CG_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGS1343778.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17125..17955)
                     /locus_tag="ACL8CG_001181"
     CDS             complement(17125..17955)
                     /locus_tag="ACL8CG_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1343779.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLATMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQTLKKGDYITLLLATLFLVASLLLILQNQGRFYNPWK
                     "
     gene            complement(17940..19622)
                     /locus_tag="ACL8CG_001182"
     CDS             complement(17940..19622)
                     /locus_tag="ACL8CG_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343780.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQIQLQTELVKETPALQSLFILEEVSFSYNDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVNEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(19724..19981)
                     /locus_tag="ACL8CG_001183"
     CDS             complement(19724..19981)
                     /locus_tag="ACL8CG_001183"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343781.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(19988..20536)
                     /locus_tag="ACL8CG_001184"
     CDS             complement(19988..20536)
                     /locus_tag="ACL8CG_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGS1343782.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(20551..21399)
                     /locus_tag="ACL8CG_001185"
     CDS             complement(20551..21399)
                     /locus_tag="ACL8CG_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGS1343783.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            21587..22936
                     /gene="trkA"
                     /locus_tag="ACL8CG_001186"
     CDS             21587..22936
                     /gene="trkA"
                     /locus_tag="ACL8CG_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGS1343784.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            22940..24379
                     /locus_tag="ACL8CG_001187"
     CDS             22940..24379
                     /locus_tag="ACL8CG_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS1343785.1"
                     /translation="MNKSMIHYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(24505..26184)
                     /locus_tag="ACL8CG_001188"
     CDS             complement(24505..26184)
                     /locus_tag="ACL8CG_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS1343786.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWIRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSTFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(26254..27666)
                     /gene="lacG"
                     /locus_tag="ACL8CG_001189"
     CDS             complement(26254..27666)
                     /gene="lacG"
                     /locus_tag="ACL8CG_001189"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS1343787.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(27676..28020)
                     /locus_tag="ACL8CG_001190"
     CDS             complement(27676..28020)
                     /locus_tag="ACL8CG_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1343788.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(28188..30074)
                     /locus_tag="ACL8CG_001191"
     CDS             complement(28188..30074)
                     /locus_tag="ACL8CG_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HGS1343789.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEEKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(30076..31398)
                     /locus_tag="ACL8CG_001192"
     CDS             complement(30076..31398)
                     /locus_tag="ACL8CG_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1343790.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDSVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            31566..32789
                     /locus_tag="ACL8CG_001193"
     CDS             31566..32789
                     /locus_tag="ACL8CG_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS1343791.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            34223..34507
                     /locus_tag="ACL8CG_001194"
     CDS             34223..34507
                     /locus_tag="ACL8CG_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343792.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            34500..34649
                     /locus_tag="ACL8CG_001195"
     CDS             34500..34649
                     /locus_tag="ACL8CG_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343793.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFMAL"
BASE COUNT        10560 a         7551 c         6003 g        10577 t
ORIGIN      
        1 ttctatatta gtaaaggtct aaataattat caatttccca ttgtgaaacg aaggttgcat
       61 aacttgccca ttcgattcgt ttggcttcaa ggaagctagt gtagatgtga tctccgagag
      121 cagctttaac cacttcatct tctgtcaaag ctttcaaagc gttgtgaaga gttgatggaa
      181 ggtctgtaat accagcttcc ttgcgctctt ctgctgtcat gatgtagata ttttcttcga
      241 taggagctgg tgcttcgatt ttattttcaa taccatacaa accaacttcc aaaagaacag
      301 ccatagcaat gtaagggttc gccattggat ccactgaacg caactcaaga cgagttccca
      361 taccacgtga agcaggtacg cgcacaagtg gcgaacggtt acgaccagcc caagcaatgt
      421 aaacaggcgc ttcataacct ggaaccaaac gtttgtatga gttaactgtt gggttcatga
      481 tggcagtata gttgtaagca tgcttgatca aaccgcctag gaaatggtaa gctgtttctg
      541 acaactgcat tccttttgga tcatttggat caaagaaggc gttatttcct tctgcatcaa
      601 acaaggacat attacagtgc atacctgagc cagcaatacc aaattttggc ttcgccataa
      661 atgttgcgta aagtccgtgt ttgcgagcaa tggttttaac aacaagttta aagatttgaa
      721 tcttatcaca agcacggaga acttcatcgt acttaaagtc aatctcatgc tgtccaaccg
      781 caacctcgtg gtgactcgct tctacttcaa atcccatttt ggtcaagaca ttcacaatct
      841 cacgacgtgt gttgtccgca aggtcagtag gtgccaaatc aaagtagcca cccttgtcat
      901 tcacttcaag tgttgggtcc ccattttcat ccaacttaaa taggaagaat tctggctctg
      961 gaccaaggtt gaaggatttg aatccaactt cttccatgtg acgaagagct cgtttcaaat
     1021 taccacgagg gtcacccgca aatggttcac cttctgttgt ataaacatca cagatcagac
     1081 ctgcaacact tccattttca tctccccaag ggaagactgt ccatgtatcc aagtccgggt
     1141 acaagtacat atccgactca ttgatacgta caaaaccttc aatagaagat ccatcaaaca
     1201 taaccttgtt cgacaagacc ttatctaact gttcatctgt agcaggaatt tcgacgtttt
     1261 tcatggttcc caaaatatct gagaacataa gacgaataaa ggtaacattt ttttccttga
     1321 cttcacgacg aatatctgca gctgtgattg gcataagttt tctccttaat ctatgactac
     1381 ttgcggttgc ctaaccgcga ccaaaaggtg actgtactga agcaaaacgc ccctgttgga
     1441 ggagttcatt gtgaagtgca cgacgtactt cagtctgact aaccgctttc ttggatttcg
     1501 cttcacgttc agcatatttt ttcttaatgg cagcgatatt ataaccttca gagatataat
     1561 ctttgatttc aagcagacga tccatgtcat tcaaggaata catgcgacga tttccttcgt
     1621 ttcgatcggg cttgatcaac tcttgatctt cataataacg aatctgacgc gccgatagat
     1681 cggtcaactt cataacactg ccgataggaa aaacagccat atttcggcga aattcttttt
     1741 ccttcattta caatttcctt ctttctgtct attatagtct aaaaaaagac aaacgtcaat
     1801 tgataatgtt ataaaatgta acattatttt tcttttttct ctaaaaagag acgaatacga
     1861 tcaatatcgt aatttacgat aattgcgaca aaaactccca taaacgtttc taatacacgc
     1921 acaaacacgt acaaaattgt ctcaccactt ggaattgata gggtaatgat taacatagct
     1981 gctacaccac caataacccc tgctttgtta ttcatggcta catttgtcat aatggttaac
     2041 atggtgcaga ttggaacaac taccaaggtc acccaaaagg cttcgtggaa aaaggtattt
     2101 aataagaaga agaccaaggc atagagtcca ccgatactat ttcctagaat acgcgaagtc
     2161 ccaaaatgaa cactctcatc aaaactctcc ctcaggctaa aaacggctgt caaagcacca
     2221 atttgaagac ctttccagcc aaaaaagcca aaaatcaaga gaactagaaa aacagcaata
     2281 cctgttttaa aggttcgcat accaagtttg aactgggatt tatcgaattt atatttttta
     2341 aaataactca taatctcaac tttctatttc cattttatca taaatcggtg atttttatga
     2401 gtaatagttg agaggaagcg tttttatttt aagcaaaaga aaagaggaac tttcatccct
     2461 ctcttctttg atttgtttat aaaatcttat ttttctgtca aggctgcaag tcctggaaga
     2521 accttacctt caagaagttc cattgatgct ccaccacccg tactaatcca tgagaacttg
     2581 tctgcacggc caaggttaat cgctgcggca gctgagtcac caccaccgat gattgattta
     2641 actcctggtt gtttcacgat agcgtccatc acaccgattg taccagcttg gaaatctggg
     2701 ttttcaaata cacccatagg tccgttccat acaactgttt tggcaccagt caaagcttcg
     2761 tcaaatttgg cgatagattt tggaccgatg tcaagaccaa ggaagccttc agaaactgct
     2821 tcaccttcag tgtcacgcac ttcagtgtaa ccagcaaatg cgttagcttc ttttgagtca
     2881 actggcaaga tcaatttacc atttgctttt tcaagaagag ctttcgcaac atccaatttg
     2941 tcttcttcta caagtgagtt accgatttcg ataccttgtg ctttgtagaa tgtgtaagtc
     3001 atcccaccac cgataaggac tttatcagct ttttcaagca agttttcgat aacaccgatc
     3061 ttgtctgaaa cttttgaacc accaaggata gccacgaatg gacgttctgg agtttcaact
     3121 gcttcttgga tataggcaat ttcgttttca agaaggaaac cagcaactgc tttttcaacg
     3181 tttgctgaga taccaacgtt agatgcgtgt gcacggtgag ctgtaccgaa tgcatcgttt
     3241 acgaagatac catctccaag tgatgcccag tatttaccaa gttcaggatc gtttttagat
     3301 tctttcttgc cgtcaacatc ttcgtaacga gtgttttcaa ccaagagaac ttgtccatct
     3361 tcaagaacgt tgattgccgc ttccaattca gcaccacgag tgacacctgg gaaaacaaca
     3421 tcttgaccaa gttttgctgc caagtcagct gctacaggag caagtgattt accagcttta
     3481 tcagcttctt ctttcacacg tccaaggtga gagaaaagaa ttgcacgtcc accttgttcg
     3541 atgatgtact taatagttgg aagagctgct gtgatacggt tatcgttagt gattacgcca
     3601 tctttcaatg gtacgttgaa gtcaacacga acgaggactt ttttaccttt caagtcaacg
     3661 tctttaacag taagttttgc catgttacaa aaactccttt atttatttta ttcgaaacta
     3721 ttatatcaca ctttggaaat ataaggaaag atttcacaag atttttcgat atttaatctt
     3781 tatcttctct tttccgtctc aaggtcaagg ctaaactagc aagaccaagg ctggctaagc
     3841 ctgctattag ggcttcatta gcatcagctg ttcctgtatt tggcaattgt ttgcttgctt
     3901 cttctgattt aactgctgta ttttgagctg gtttttcctg tgtagctact actgctggta
     3961 ctgtttttac ttttgttcca atttcaacaa tttctggaat cgcttcttgg atgacttctg
     4021 ttgaacgaag acgacgctga ccgttttcat caacttcaaa gacatgtctt aacagtccat
     4081 ctcgtccctg tatgatgact cgttgttccc caactagcat ctcagcattt tcatgctctt
     4141 gacgatgaaa ggcaaccttt tcctcttgaa cttccaattt aggagccttt tgttgatcag
     4201 aagccggttg ataagtaggt tttggaagga ctgtgttttg tggtgctggt ttagcaggtt
     4261 gtggtttttc agcagattca taaacaaagg cataatgagt aaagtgaggt gctgtaaaga
     4321 taacatgact atccgtttgt tcaaaagcca attctactgc ctctttgcct tcaggtaaga
     4381 aaaatacttt cttaactttc ttatcttttt caattgggat tttcacaata gaagcgtaag
     4441 agagatcaac atcttgacct ttttcatcca aaccttctat ttcaaagaca tgagcatctt
     4501 ctccagcaaa gtatttcttc tcttcagcac ttgcttgaac acgctctact ttcaaaccct
     4561 tgatgacagt cttctcttta tttgagaagt gtacttcaac acctgtttta ctatcagaaa
     4621 agactgctgg cttgtcttct ttcaataaag caaccagatc ttttagactc tgtttcgctg
     4681 ttgtaagctc ttctggactc aaatctactt tttcaaccaa ggccttgttt ttctcaagaa
     4741 gcggagctag ggcagaacct gaaggatggt ttggtttggc agccaagagt tcttgaacct
     4801 cacctgttaa gcgatcaagt tctgtctttt cttccttaaa tttctcttga ccattcagag
     4861 ctttatgagc ctctgtcaat ttattaagtc ggtcattgac ttgatcttgg gtgctagttt
     4921 catggtcttt caacacttgt tcggccgctt caattgcttt caagaaagct tcttttactt
     4981 ctggtgaagc aaagttatag accaccttgt tcttagcagc ttcaacttct gctaattttt
     5041 gtttgaggta ctcatcgttc aatgctgctt ttggagatac caaaacatca aagctaactt
     5101 catggccttg gtaatgaagc gtcaaggttt gacgaccagt cttttgagca tcgtaaccag
     5161 aaatttcaac tccctcatca gtaaaggaat gttcttccat ggtgtcattg ctataagcca
     5221 ctgcaaagcg tccttcagac aagtctaagc tatcaccaac taggtaatct tttttcggtt
     5281 cctgacttac ttcaattccc aaaatagttt tcggacttgc ttcgtctttg ccagtgacag
     5341 tcactgacaa attagcattt accggttgtc ccaaatattg gagagtaaga ttctgttctc
     5401 ccttatgatg cgtatcaaaa cctgatactg atacacctgc gtgagttagg cgaatgagtt
     5461 cgtcctcagt tcctccttca tactgaactc gaagaacacc acctctaagg tccaaatcct
     5521 ccccttcggc gtagcttgtt ttcttaggtc ctgtttctag gctgactgac ttgattcttc
     5581 tgtcatcttt tggaacggaa actgctagga cattactaat ttccttgcct ggcaactggg
     5641 tacgataata aagaagacca gattgatttg tcaaatccaa tggtgcactt gctaggtctc
     5701 ctccaacttc gctcttcaag gttgcaagcg gagtttgaga atttggatta tcataaacag
     5761 taatagttgc tccagccggt acatctgaaa agccaacttg taccttgtta ttgcctagag
     5821 aacgggctgc agccttggcc atcggaatat tgacactctc agtatcaagc ttttcataca
     5881 ttttccagtt atagatacga atagccttcc atggagttcc attgtcagaa gtgacaacat
     5941 tcaagcgcca gtcttgagca gtgattggtt tatcaagagt gatatctgtc acgtgtgctt
     6001 tgttgccacg gacttcctta gctagcttcc actcaccatc tgcatcttta taataaaggt
     6061 caaagtcttt ggtgttcatc aagccatcgt taacagactc accaccagcc cctgcatgat
     6121 ccatgaccca tctaacaacg gtacgtggct tggtcaaacg aatatccaca ctaccactca
     6181 actgagctga agaccattta tctgacaagc tagtaatggt accgttcaac ataccttcaa
     6241 taccttctcc accttcagtc ttagggaaag tactatcaat aactgttgca cctggaacga
     6301 tattttcagc tagtggtttt ggtaggctgg tatcttttac agtcataccc caatcaaagg
     6361 ttgtggttgc agcttctgaa cgaactccat ttttaccgac tgctacaacc ttcagttctt
     6421 gagttgtacc ctgagcactt gctgagcggc taacttttgg tagataaata gttgtagaag
     6481 atgagccagt tagtaatttc cagctgtctc catctttttc ataaacttca tagaaatctg
     6541 catccttgtt gcctttaaat tgcacaactg cttccgcttc ttgggcattt ttaagagatt
     6601 gtttcactac agaaaagctt gtcggcgatt gtggctcttg gtgattgtcc gagatagtta
     6661 attgtccgag gttgaactga taatctttta cagcaccttc atgctcgaaa aatagtttaa
     6721 ctgcatagat ggttttacct gctagtgagc tgagatcaaa ttcttcattt gtccagttgt
     6781 cagaaagggt tagctctttc catgcatctg catcatcgaa tttgtagtct gaagttgtag
     6841 agaatgccat ataaacttta gaaccttttc ctcccttgtg ggcaacacga agtttggtct
     6901 tctcagttac ttctaactta gtagaataaa gtctcacatc ctgaactgtc ttaccggcta
     6961 catcaccaga gaatttaagg gaatttccgc cattataggc atctgtaaaa tcatattctg
     7021 cacgaagttt ttcccctgtt gaagtctgcc accagcgcca tgttggaaga acacctgata
     7081 ctgaacgata attccactca gaatccttag aaaccttacc atctacgaac cattttttac
     7141 catgacctgt attaaaagaa gtagtaaaag tattacctac cgctggcgta cggtccgcaa
     7201 ctaggttagc aataccatac caatctttgt cacctggttt ttggccagtg gggtctcctt
     7261 gataacctgt aaagaagata tcttcatttt tatgataatc ttcaccagtt tttcctaaac
     7321 ttgtaatggt atctggggca aataaaccaa gagaaaggcg caatttccca ttttcgtcta
     7381 aaatgtcatt ccacttaacc tttgtcttgt aggaaccacc ctgttgcaat tccaaacctg
     7441 caaatacatc ataaggatta cgaccaatcc agttggcagt tgcaatagtg taatcatttt
     7501 tagccttatc ccagttaaag ttagcaaaga agttatctgc cggaacctta tctccttctg
     7561 gttgcatgaa ttggtagttg tattctccca aaccatcttg atggtaacgt ccatagttat
     7621 aggtcatggc atcataccaa gaatacttga ttggatggtt taccttagca gcatattcct
     7681 tgctatagag cataaactgg cgcatctttt ctccaagagg tttaaccaaa tctccagttg
     7741 tttcttggtt gatgaaatag ccatcatagc cataatactt ggccatgtct accaatttac
     7801 gggcaattgg gaagctacca tctgcgtctt gcttcaaagc ttcagcaaat ctttcttgat
     7861 ctgcaatact attagaccag ttgaagaaga gtgtaccgta tacaggaacc ccgttacggt
     7921 gacctgcatc aataacgtca ggagttggta cgagaccttc ccagaagacc attgaatcta
     7981 gatattgcca atagtcaaaa gcataggcct tgaactcttc tccaccaaca gaagcatggt
     8041 cttttgcttt agaattagtg tttgataagg cttgaacttt tgcttccttg ctagcttttt
     8101 cattgactaa atgacctgtc cgacgtgaag cgaggacaac agatccgcgg ttaatagcat
     8161 catcttcacg agcacctggt tcccatttta acaattcttc ccaagaatta aatttgattt
     8221 cctttggttt taatgttttt tctgtatttt tagggacatc tggctggact tctttttcag
     8281 tcttattagc ttctgctgct ggcttagact catccccttg gttagttgct tcgggctttg
     8341 cttctgtttc cttgtcagac ttaggttttg cttctgcaga tggtgtttct gcaaccgcct
     8401 cacttgcttt ttcctctggt ttagctgcgc tagctgcttc tgcagtttca gatgctgtcg
     8461 ctactccttc tgccttttct agcttgtttt ctctagtatg ttccccttca ttctgcttat
     8521 cagcttcatt ggtcgaatgc tcactctctc ctgaaacaag ctctgtatta gctccgctat
     8581 tttcaggaac tgcagtttct tcagccaagg ctggaccagc aaataaaaca gcaccaatca
     8641 tcagcgagca ggctcctact gataacttac gaatactgta acgacaacgt ctttcaaaaa
     8701 atggattctt cattttctcc tcctaaaaga ttgattttgt tgtttttaag aaagcgcttt
     8761 atattctgtg gttttttaac tctagaacca tgataatcac atttttatcc taaaacattt
     8821 ttagacaaaa aacaatagct gttttcacaa atctaaaata aggttaaaaa ctcttaaaaa
     8881 taatacactt atcaattata attttctttt acaaacttga cattaacact tgttagattt
     8941 acttttatcc tttaaaatag aataggagat attccgcgat tatttttcgg aggaaaaaga
     9001 aatgtccatt aattggcagg aaattttatt tcacttttta ggtggtctgg ggctattctt
     9061 atatagtatc aagaccatgg gagacggttt gcaacaagct gctggagatc gccttcgttt
     9121 ttacattgac aaatatacta gtaatccttt ctttggagtt ctggttggta ttgggatgac
     9181 tgctctaatt cagtctagtt ctggtgtaac agttattaca gtcggcctgg tcagtgccgg
     9241 tctcttaacc ttacgtcagg ctatcgggat tgtcatgggt gctaatattg ggacaactgt
     9301 cacatccttt ctcatcggtt ttaaattagg taactatgcc ctacctatgc tctttatcgg
     9361 tgccgtctgt ctctttttta cgaaaaatcg gacagtcaat aatatcggac gcatcctctt
     9421 tggtgtcggt ggtatctttt ttgccctcaa tctcatgagc ggcgcaatgg ctccactcaa
     9481 ggatttacag gtctttaagg actatatgat tgagctaagt aagaatcctg ttttgggtgt
     9541 ctttgtcggt actggcttga ccttgctaat tcaagcttct tcggctacca ttgggatttt
     9601 acaaaacctc tacgccggcg atctaattga cctacaggga gctttgccag ttctatttgg
     9661 tgacaatatc gggacaacca ttacagccat cattgcctct ttaggggcta atattgcagc
     9721 taaacgggta gcaggagctc atgttgcctt caacgttatc ggaacagtcg tctgcgttat
     9781 ttttctagtt ccttttactg tcctgattca ttggtttgaa actacgctaa atctagcacc
     9841 ggaaatgacc atcgcctttg ctcacggaac ctttaatatt accaacacca ttatccaatt
     9901 tccatttatc ggagctctgg cttactttgt aaccaagatt attcctggag aggacgaggt
     9961 tgtcaaatac gaacccttat atcttgatga acatttcatc aaacaagccc catctatcgc
    10021 tctaggaaat gctaaaaaag agctcttgca cttaggaaac tacgctgcta aagcctttga
    10081 cctttcctat aagtacatca ttgacttgga tgaaaaagtt gctgaaaaag ggcataaaac
    10141 cgaagaagca attaacacca tcgatgagca attaacacgt tatctcattg ccctttcaag
    10201 cgaagctctc agccaaaaag aaagtgaagt gcttaccaat atccttgatt cctcccgtga
    10261 tttggaacgg attggagacc acacagaggc tctactcaat ctgactgact atcttcaacg
    10321 gaaaaatgtt gaattttctg atgccgcctt gaaagaatta gaggaagttt accgccaaac
    10381 tagtgacttt atcaaagatg ctctggatag tgtggaaaac aatgatattg aaaaagcacg
    10441 cagtcttgta gaacgtcatg aagcaatcaa taagatagaa cgtgttctca gaaaaaccca
    10501 catcaaacgc ctcaacaaag gcgaatgttc aacacaagct ggggtcaact ttatcgacat
    10561 catctcacac tacactcgtg tatcagacca cgctatgaac cttgctgaaa aggtttttgc
    10621 agaacaaatc taagaaccaa gaagctatcc atcataattg gatggctttt tactttttcc
    10681 taagcaagac taggctgaat gaaactgaaa gagtattctg cagatatata gtatattgaa
    10741 actagaatag gacacctcta tttctaaaac attgttagaa atagatttga ctgtcctgat
    10801 tgatttgtcc tgttattatt tcattttact atagtgaatt aaattaaaaa agtatagtgt
    10861 attgaatcta taacagtcca tcttaactgc taaaatattt atataaatta atttgacttt
    10921 cctgatagag atgttcacat cttatttcaa ttcactatac aatccagttc ctaaaacttt
    10981 gctagaaatt gatttggctt tccgaattaa tttgttcaga ttttatttca tttcaatata
    11041 ctgataaatc cattcactag cacagggcaa gagggagtcg ctattgattt caacggtagc
    11101 aggtacatac agaggactcc tacctcagat atactgcaat atcatcgtgt gcaaaaaacc
    11161 tctgagattt ttctcaaagg ttctgatttt gctaattgct gttctcaacc gctgcagtaa
    11221 caaaggcaat gtagagttct tctggtcggt ttggacggct tgacagttca gggtgatact
    11281 gacaagctac aaagaattta ttttcaggaa tttccacgat ttctaccaaa cgattgtctg
    11341 gagaaactcc tgaaaagaca aagcctgctg cctcaaactg ctcacggaag gcattattaa
    11401 actcataacg gtgacggtga cggcgttgca ccacttcttg attgtgataa gcagcagcag
    11461 ccttagagcc acgtttcaac ttagacggat aaagtcctaa acgaagggtt ccacccatat
    11521 cctcaatatc aatctgatca cgcatgatat caatgatagg gtattttgtt tctggtgcaa
    11581 gctctgcaga attggcacct tcaagaccta aaacgtgacg agcaaactcg atacatgtca
    11641 actgcattcc caagcagact cccaacattg gaacatcatt ttcacgcgca tagcggatgg
    11701 cttggatttt cccttctgta ccacgttgac caaaaccacc tggtacgatg atcccgtctg
    11761 catcagacaa gagttctgct acattctctg ctgtcacatc attggcattg acccaattga
    11821 ttttaacttc tgcatcattg acatagccag agtgtttcaa agcttcgacc actgagatat
    11881 aggcatcttg caactccaca tacttaccaa caagggaaat cttaacttgt ttcttgaggt
    11941 tcatgacctt gtccaccatg gctgaccatt ctgtcatatc cgctgctggt gcgtctaatt
    12001 tcaaatgatc acaaacaatt tggtccatcc cttgtgcctg caagttcagt ggaatttggt
    12061 aaaggtgttc aacatccaac gattcgataa cggcttctgg tgccacatca cagaactggg
    12121 ccagtttatt tttaattcct tgaccagctg gctcttctgt acgaataacc aacatatttg
    12181 gttggattcc caagccacgc aattctttga cagagtgttg ggttggtttg gttttcattt
    12241 caccagcagc cttgaggtaa ggaagcaagg ttgtatggat atacatgaca ttatccgcac
    12301 ccacatctgc cttcatctga cgaagagcct ctaggaatgg caaggactcg atatctccta
    12361 ctgttccacc aacctctgtg ataatgacat cagagtcggt cgttagagcg gcacgcttga
    12421 ttttttcttt caaagcatct gtgatatgag gaatgacttg aacagttgcc ccaaggtatt
    12481 ctccacggcg ttctttacga agaacttcac tgtaaatttt cccagttgtc acgttggaat
    12541 atttgttgag attgatatcg atgaaacgtt catagtgacc caagtccaaa tctgtctcag
    12601 ctccgtcatc tgtcacaaaa acttccccgt gctggtaagg actcatggtt cccggatcaa
    12661 tattgatata agggtcaaac ttttgaatgg ttactttgag accacgattt ttcaagagac
    12721 ggcctagact cgctgccaca atccctttcc caatagacga taccacacca ccagttacaa
    12781 aaatatattt cgtagacata gattcctctt tctaaaatgc tcaaggtctt gttaactacg
    12841 aggggatata gaaaacaaga ccctactaat aagaataatc tgggacgact gcaccagatt
    12901 cacaactaat actcttcgaa aatctcttca aaccgcgtca acgtcgcctt gccgtagata
    12961 tgtgttcctg actttgtcag tcttatctac aacctcaaaa cagtgttttg agcagcctac
    13021 ggctagtttc ctagcttgct ctttgatttt cattgagtat aaaatacaag aagataactt
    13081 cttgaaaaaa caaaaatagc tccctaagaa ctagggagcc ccgacctcta aaagaggtgc
    13141 ccaaacaata tgatacctaa aaataggata attgtcaata gctaactctt attcctcgct
    13201 ggtttcagcg tcgtcatctg aaaactcgtc gtcgtcttcg ttgagatcca catcttctcc
    13261 caagtcatct ggagcgattt cgttgatttc tgcatcataa gcttccactt catttttttc
    13321 atcatctgga ttttcatcat cgtatgaaag agctggatct gcttcgtatg catcttcgtc
    13381 ttctggatca tctgcattgt agtcaatggc atctgaatca ccatccataa aggcattgac
    13441 acgttttttc ttagcttttg gtgctacttc atcgtcgtca ttttcttcaa gagcgatgat
    13501 ttcttcgtcg atttcgtcca caccatacca tgaacgaaga ccccatttgt tgtccccaag
    13561 tgagatgaag ctaccgtcaa agttcaactc tgtgtagaac aaaggcaaag cttcgcggat
    13621 atcgctgttt gatgttccaa ggtagttttg aatttcgttt acaagatcgc taaaatgcat
    13681 ctcatgatcg cgaccacgaa gttctaagat agcacgcgct acctcaatca tagatagttc
    13741 acttttttct tgcccagcaa atacttctaa ttccaaagcg tttctcctca tttatactac
    13801 tatcgtcaga gcgaacagac tctgacctca ttttatcatt tactctttat tttacgataa
    13861 ttttgcggaa tagtcaaagg ttaaggggga gaaagtggca ggattagact aattccaata
    13921 taaaacccct tcctttttct gttgctccat tttccacaaa tccaagcgac ttgaaacacc
    13981 tcctagaagc atgattgtag gtgtagattt ccttgactct caattctttc catcctttta
    14041 ctcgagccaa ttcaatcaaa gcacttagaa tctttttcca agtcctcgat gttggtaagc
    14101 ggaattccca atcacaatgg ggagattatc ctgagatagt gtaatatccc caattggaaa
    14161 ccattctccc ttctccttga cttcaatcca aaaaagctca ccatgccgat ccaaatagga
    14221 atacatggct tccaaggtcg cttgactgta aggaagcttc accccatcta cgaggtaaac
    14281 caagttcaca tcctgatacc aagcaaaagc ttcctcacaa tgattgacct tataataagg
    14341 aacaaaacac aatgcactac cttttcaaca aaagagttgc tgcttgatta aaaccatcac
    14401 accagttata ccattttgct tcatacccat cttgagctag gatacgatct tctaaatcaa
    14461 aaacagagta aatctttctt tcctcgcaag cttgcgcata gaaatgatat agttcatcac
    14521 caccatctct atcccactca gcagaaatcg tatcccgacc tgccaataaa gcctgataag
    14581 ccctgtgatg cccatctgta atcagcaaac aatctccaaa ggcaagaata ctgattggat
    14641 cgacttggat tgtttctgcc gactggtaaa gcatctgaat atcttgcaac ttcttttctg
    14701 ataaatatag ttgagtcgga tgaagatctg ctatattgac tttcatttct ttctctcaag
    14761 ggaattcgat actcacttct gtttgccttt aaatcgccat tggaagcgga gcttgtcata
    14821 aaagggaaac tcgataaaca ggactcccaa gcccacacag agactggcaa ggacgtctga
    14881 tgggtaatga actcccagat agactcttga taccagcaca ctgactaggt agaggccaag
    14941 gacgatttgt acgatttttc tccagacctg atctttaatc cgctgactaa gaataacaat
    15001 caaagtccct accatcagcg ttacagctag agaatgccca cttgggaagg aaaatccctt
    15061 ctcttccacc agatgtaaga tagctggtcg tgggcgctgg tagatatttt taaaggtcac
    15121 gattaaaaga cctgccaaag ccagatttcc cagcatgaag aaactttcta tcttccatcg
    15181 cttacgataa aagacaaaag ctgtaatgac aacccaagtg ataatcactg ggatatcaat
    15241 cagacgtgtg agggctcgaa aaagaatagt caaataatct ggtaagtctc ctcgaatggc
    15301 agtctgaatc gattggtcaa aattgaccaa catttcaggg taaaatttga ccatatagcc
    15361 aagaataacg aaaagtaaaa gggcaaaact gcccttcatt aaaaatgttt gtttatcttt
    15421 catagtgttt taaggttggt ttcaaaagga cgtacaacaa ccagaatgaa acggaaaaga
    15481 ttacaccctc aatcaagtta aaaggtaata ccatggtcat taggtagttg gaaaatccca
    15541 aaatttttcc aatatcaaag ttagcaaact tagcgtacaa aggaacagca taaacatagt
    15601 tgagaaccaa catggccaag gttaaaccaa tagttccagc tagagagcct agtaggaaac
    15661 gaagggttgt ccgttccttt ttccaaatca aagcaaatac gatgacaaaa actcccaaag
    15721 ctacgatatt catcggcaaa ccaatgtaag tattcactcc ttggctgtta agaagcaatt
    15781 tcaagagtga gcgaagcaag agcactccta gagcagcagg caaatccatg accaccagac
    15841 ccacaaggac tggcaagata ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg
    15901 gaaagtcaaa gtacatcagc acaaatgaga tggctgatag aattgcaatg gtcgaaagtc
    15961 gacgtgtgtt tgtcataaca ggttcctcca attttctata aaatcagaag aagttggaaa
    16021 ggattcctct atctattctc actttttata tcccaaaagt tccctcttac tctattaaag
    16081 aaaaacaaag caagtggtta caatccggct ataaatctat caaaacagac aaagctattc
    16141 tttcgtcttc tcccatccag actatactgt cggttgtgga atctcaccac atcagcttgc
    16201 gctcgcggac ttctttaaag agaaggaaat agagattttt cttttagact aggcgacaag
    16261 ctgtaggcat aacttctggt taggcaaagc ttgtcaacaa agtataaaag gaaaagatca
    16321 tttcctagtt aaagtcaccg ccggtcggga atcacaccct gccctgaaga ctcttttatc
    16381 ataacaaaaa acgcttgcaa gcgcaagcat tttgttcatt ttcatttttt atttcaattt
    16441 atccacttca taggtatgga cgagctcaag acctgcaaag ttctgctggc gaagagcctc
    16501 atagacaatc atgcagacgg tattagacac attgagactg cggacatgtt catcattcat
    16561 gggaatacgg agagccttct caggatgttc tcgcataaaa tcttcaggta agcccttgtc
    16621 ttcacgtcca aaaagaaaat aatggtcctc gtcagtcgat aaatccacct cagaatagac
    16681 tttttccgcg aatttcgaaa tcagatagag ttttcccttc atctgagata tgaaatcttc
    16741 caaactctcg taaaaataaa tctctagctt atcccagtaa tccaatccag cccgcttcat
    16801 cttgcggtca tcaataggaa agcccatagg cttgatgatg tggaggggag aattggtcgc
    16861 agcgcaagta cgcgcgatat tgcccgtatt ttgtggaatt tgaggttcaa ataatacaat
    16921 gtgatttgtc atgacttgct tcctttcacc attgcaaaaa aatagccaca ctgcccggag
    16981 tcaagctcag cagacagcgt ggttaaggca tcgttaactt acctcacaac aggtttgaag
    17041 taaatcagcg aaactacttt cttagtataa cactttcaga atcattgtca atagaaacga
    17101 cttgattttt tcaatttttt caagctattt ccaagggttg taaaatcgtc cctgattctg
    17161 caagataagt agtaaactag ctactaaaaa caaggttgcc aagagcaagg taatatagtc
    17221 tccttttttc aaggtctgat aactatacca tgtgcgtttt ttctctttcc caaagcggcg
    17281 aagctccatg gcagtcgcaa tggtatcaat gcgttctagc gagctaaaaa tcaagggcgt
    17341 aataatgagc agattgcctt tgattcgttg cataagagaa gctttcttgg ataattccat
    17401 cccacgcgcc tcctgagaca tcttgatagt aaagaattct tcctgcaaat ctggaatata
    17461 gcgcaaggtc aggctgacag aataagcaat cttatagggc acaccaattt gatttaaact
    17521 ggaagcaaac tgactaggat gggttgtcat caaaaagata atagccagag gaatggtgca
    17581 aagatactta atggccaaat ttagcagata aaagagctcc tggctggtta gagtgtagac
    17641 accgattccc tgccaaatca cacttctctc tccataaagt ccaaccccat actcgggaga
    17701 aaagagatag accatcaaaa cgtttaaaac ggcaaatacc gtcgcaaaaa cggctacaaa
    17761 ggaaacatct ttaaagcgaa tttctgataa atagaggaga aagactgaaa agatggcaat
    17821 cagcaagagc attctggtat catagctaat catggtcgcc aatgatacca gaatgaaaaa
    17881 gagaagtttc ccagctcctg acaagcgatg aatcacagta tctctatgct ggtaaccgat
    17941 taatttagct tgcatccctc tctcctctct ttgtaaaatg ccgttaaatc caatggatcc
    18001 acatctagtt tcttagccaa gttaaagatg gaggtttctt ttagattggc ttttactaac
    18061 agctcaggat cgctcaacag actggctgga acagtatcgg caatcaattc tccatccacc
    18121 atgacaaggg ctcgatctga ataatccagc atcaattgca tatcatgggt aatcatgaca
    18181 atggtatgcc cttgttgatg cagttcttcg agaaattcca taatctcagt atagttcttc
    18241 tggtcttgac ccgcagtcgg ttcatctagg aggataattt cagcgcctaa gaccaaaatt
    18301 gaagcaatgg tgacacgttt tttctgacca aatgacaggg cagaaatagg ccaattacgg
    18361 aattcataaa gtccacagat tttcaaggtt tcatagactc tcgtttcaat ttccttctca
    18421 ttcacacctc gcaaacggag ccctagagcc acctcatcaa aaatcatatt ggttgaaatc
    18481 atttgattag gattttgtag cacatagcct actcgttccg cccgctctgc aacagaatcg
    18541 ccttttatat cctgtttttc ccaaagatag cgtccttccg tctgaataaa gctacttata
    18601 gccttggcta gagttgattt ccctgctcca ttttttccga caatagcaat cttttcaccc
    18661 tttttaatat ctaaatgtag ggattttaaa atcggtctat cattataaga aaaagatact
    18721 tcctctagta taaagagtga ctgcaatgct ggggtttctt ttaccagttc cgtctgtaac
    18781 tggatttgcc cttttgagat agacaagtta tccagatctg ctaattgttc ttccttgact
    18841 aagtccacac ctaattgacg gagagtcgtt agataaaggg gttctcgaat tccattttga
    18901 gtcaataaat cagtcgcaag caactggtca gggctcccat taaaaaggat acgaccatcg
    18961 tttatcaaga caatccgatc cacagggcga tgcagaacgt cctccaaacg gtgctcgata
    19021 atcagagtcg tcgtcccctc ttccttatga atctggtcaa tcaattcgat aatatcctga
    19081 cctgacttgg gatctagatt ggcgagtggc tcatcaaaca agagaatcgg actttcatca
    19141 atcaagacac cagccagact gactcgctgc ttttgtccac ctgacaaatc ctgaggacgc
    19201 tgatccagta aaggaagaag gtccagcttt tcagcccatt tataaacacg acctttcatc
    19261 tcatctaggg ctgtcacatc attttccaga gcaaacgcca aatcttctgc cacagacaag
    19321 ccaataaact gcccatctgt atcctgcaaa actgtgctaa ccagatgaga cttatcatag
    19381 atgctcatat caaaggctgt ttgacccttt atcaaaaatt ctccatatgt ctgacccttg
    19441 taaatattgg gaataatccc attcaaacac tgacccaagg tagatttacc tgatccagat
    19501 ggtccaacaa ttaagacttt ctctcccttg taaatggtca agtctatccc ttgcaaggtc
    19561 ggttcttgtt gtgtttcata ccggaaagag aaatccttcc actcaattat agcttctttc
    19621 atcttactct cttcattcgc ttcttagact tctattttat cataaatcaa gcccttcttg
    19681 cagtctcttc tcttaaaatc ttagcgccaa aaagattcct atcctagctt acttgcctaa
    19741 ctaatctata aacatcgaaa aagactagtt gcccagcctt ccccatcatt ttatactctt
    19801 cgaaaatctc ttcaaaccac gtcagcttcg ccttgccgta ggtatggtta ctgacttcgt
    19861 cagtttcatc tacaacctca aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa
    19921 tttcaaaaca ctgttttgag caacctgcgg ctaacttcct agtttgctct ttgattttca
    19981 ttgagtatta gtcctttttc aaacttcctg cacgagtttg ggttcctgca taggcaagta
    20041 agagaagagt tcctgcaata gctacagata caccattggc aattcccgca acaatccctt
    20101 gtgcaaatac tttttctgcc gcttcttgat aaatcacaac atctccaagt ggtgccaaga
    20161 caccccaaac aagggcattt gcaagtagtt gaatgaggtt aaaaataaga atatctttcc
    20221 agtcaaaaac accattgatc acgcgaacgt actttctaaa aagtcccaca actaaaccaa
    20281 agagtccgct agcgataatc caagtccacc atagaccata accagcaaga gagtccttga
    20341 ttgcatgacc aatcaacccg acaagcaaac cgataatcgg tccaaaaata atagaaagta
    20401 gcgcttgtac cgcatactga agctggatgc ttgtatttgg aacaggggtt ggaatgttga
    20461 tcatcccgat gacgacaaag agggcagcgc caattccgac agcaacaact tgtttaattg
    20521 taaatttaat ttccatacta ttctcctatt ttatccttct attttcttta tttcaatggt
    20581 ccaagatgaa ccgacaccta cattataggc cttggcaaag gaaccttggt tgatagccaa
    20641 acctaaacga tagagagagt tgatgtaaag gatgggttgc ccaattctca catctgcaaa
    20701 tgatttgcca tagacaacct gattttgata gaccagcata tcagcatgat agatggtcac
    20761 ttcaaaacga tcaccaaatt ctggttccag cttgtaaaat tcttcccgtg tgatagaggt
    20821 ccaaagcgaa ccgaaacgca catccagaat atcaatggct cccttcacca gatgatcttc
    20881 tatgatggtc gctacgactg gaagctctac aatctgttcc acactgagct ctggccctac
    20941 ttcctcaaaa gtaatgtgac cactggccag tttagcacca gtataggcat agacatcacg
    21001 accgtggaag gtataagaat gctctgtgtt ttgacgccta ttggccacct cagaaatctc
    21061 acgaatggct acaatgccaa cgtgtttctt gataaaggaa agcgtcccat tatctggcgt
    21121 gacaatgtat tgattttttg cagtcttggc aactacactc ttacgtttcg aaccgacacc
    21181 tggatcgaca accgatacaa acgtcgttcc ctcaggccag taatccaccg tctgaaagag
    21241 acgatagctc ccctcaaaaa tattataagg cgtgatatcg tgcgtcaagt gatggatttt
    21301 taaggttgga gactcttcta aagccactcc aatcatagcc gacaccgcac catcaaccag
    21361 accaaagtct gattgtaata ccagtaaatt attgttcatt ttatctcctt gtatatcctt
    21421 tatcatacca tatttcagag aaagtcgcta atagctattt caattggtta gggtatagtt
    21481 ttaccttata gcgaattttc actaaaagct cttgttatta gctagtaggt gcattttttc
    21541 ttgaaaaagg gtatgatagt tacatcatga aaaagtaggt tttattatga aaattatcct
    21601 tgtcggaggg ggaaaagttg gttttgccct ctgtcgctcc ttggttgcag aaaagcatga
    21661 tgttttgctg attgagcaag acgaagctgt tctcaatcat attgtcagtc gctttgatat
    21721 cattggtatc cttggtaacg gggccgattt tgccattctt gagcaagcca gcgtccaaga
    21781 ttgtgatatc tttatcgccc tgactgagca cgatgaagtc aacatgattg cagcagttct
    21841 agccaagaaa atgggagcta aagaaactat cgttcgggtg cggaaccctg aatattctaa
    21901 ctcttatttc aaggaaaaga atattctcgg tttttctctt atcgttaatc ctgagctctt
    21961 ggctgcccgc gctatcgcga atatcattga cttccccaac gccctgtctg tcgaacgctt
    22021 tgctggtgga cgcgttagcc tcatggaatt tgtcgtcaag tccaccagcg gtctttgcca
    22081 aatgcccatt tctgattttc gtaaaaaatt tggtaatgtc attgtctgtg cgatagagag
    22141 ggatcatcaa attatcattc caagcggtga catgactgta caggataaag atagaatctt
    22201 tgtcactggt aaccgtgtcg atatgatact cttccataat tattttaaat cacgcgccgt
    22261 gaagagcctt ctcatcgttg gagcaggtag aattgcctat tatctacttg gtattctcaa
    22321 agatagtcgt atcgatacaa aagtcattga aatcaatcct gaaatcgcca gcttctttag
    22381 cgagaaattc ccaaatctct acatcgttca aggagatgga accgcaaaag atatcctgct
    22441 ggaagaaagt gctcaacact atgatgccgt tgcgactcta acaggagtcg atgaggaaaa
    22501 tctgattaca tctatgttcc ttgacagggt aggtgtacag aaaaatatta ctaaggtcaa
    22561 tcgtaccagt ctcctcgaga ttatcaatgc gcctgatttt tcaagtatca tcacacctaa
    22621 aagcatcgct gtagatacga ttatgcactt tattcgtggt cgagttaatg cccagtattc
    22681 agaccttcaa gccatgcacc atctagccaa tggccaaatc gaaaccctgc aattccatat
    22741 caaggaagcc aataaaatga ctgccaaacc tctttctcaa ctgaaattga aaaaagaggt
    22801 tcttattgca gccattattc gaaagggcaa gactattttc ccaactgggg aggatatgtt
    22861 ggaagttgga gacaagctcc tagtaacaac cttgttgcca aacatcacca agatttatga
    22921 cttgattgcg aggtaagaaa tgaataaaag tatgattcat tacctccttt caaagttact
    22981 tttgattgaa gctgttctcc tcttggttcc tgtggctatc gctgtctatt accgtgaatc
    23041 gagccaagtc tttacagccc tcttttcaac catagggatt ctcgtattgt taggcggttc
    23101 agggagttta cagaagccaa aaaatcaacg gatttatgcc aaggagggag tcttgatcgt
    23161 tgccctctgt tggatccttt ggtctttctt tggtggtctc ccctttgtct tttctgggca
    23221 aatccccagc cttattgatg ccttttttga aattagttct gggtttacaa ctactggagc
    23281 aagtattttg aacgacgttt cggttctcag ccgttccctc ctcttctggc gaagttttac
    23341 ccacttgatt ggagggatgg gagtgcttgt ttttgcactt gctattatgg acaatgccaa
    23401 aaatagccac ctagaggtga tgaaggctga ggttccaggt cctgtttttg gcaaggttgt
    23461 atccaaacta aaaaacactg cccagattct ctatctcctt tatctagctc tcttctccct
    23521 ctttgtcatc atctattatc tagctggtat gcctctctac gatagttttg tcattgctat
    23581 ggggacagcg ggaactggag gctttaccgt ctataacgac ggaattgccc actatggcag
    23641 ctcactgatt acctatctgg tcagtatcgg agttctggtt tttggggtaa atttcaacct
    23701 ctactactac ctcatgctcc gtcgcatcaa ggccttcttt ggtgacgaag aacttcgggc
    23761 ttacttggtc attgtactgg tttctacagg cttgattagc ctcaacaccc tctacctcta
    23821 cccagggttt tcaaagagct ttgaaatgac cttcttccag gtttccaaca tcattacaac
    23881 aactggtttt ggatatggag atattaccaa ctggcccctc ttctcccagt ttatcctcct
    23941 tttcctcatg gcaatcggtg gctctgctgg atcaactgca ggtggactca agattattcg
    24001 aggcctcatc ctttcaaaaa ttgccaaaaa ccaaattttg tcaatcctat cgccccaccg
    24061 tgttttgacc ctccatgtga atcaaacggt gattgataaa gatacccagc ataagattct
    24121 caagtacttt gtcatctatg ctatgatttt gctagcgctt atctttattg tcagcctaga
    24181 tagcaatgat tttctggtcg tgaccagcgc tgtctttagc tgtttcaata atatcgggcc
    24241 tattctagga accacttcta gtttctcaat ctttagtccc atctcaaaaa ttctcctatc
    24301 ctttgcaatg attgcagggc gcttggagat ttacccaatc ctccttctct ttatgaagag
    24361 aacttggtct aagagataaa atacaaaatc cctcttttta caattgtgaa agagggattc
    24421 ttatattaaa aaagggggaa cgtttttaaa tccaagccta tctgtaagca aaatccttac
    24481 tcaaataaaa gatggaaaaa cttactacac agcttggtaa tgctccaata caaattgtaa
    24541 ggatttactt ggactctttg ttaaatgaat atattccatt cctctggtag caactatctg
    24601 aatacctaat ctttctgcat ccaccttcat ctctctataa taactccgaa cttgtggagc
    24661 cagaataatt aaatcataaa cacccataat atcataatga gctccgtacg ctcctgaatt
    24721 cgcaatcact ctaacttctg ctaattgagc gccctcgtta attgcattgg ctaattgcgc
    24781 acttgttcca gaccctgcac aaagaaccag tactttcaac tccttacttt ttatttcatc
    24841 taactcacca ggcattattt cacttgtctc ctcctctaaa ataatatcat ttgagcttgc
    24901 aacatcttct ttcatcagta actgtctatc atacgctcta cagaatggca aataaatcaa
    24961 tatgtcgaca actaaaatca aagataaaaa tacaaaggag atagattgaa aattcgttcc
    25021 aattaacaat cccaagggac caggaaaggc ccaaggtaac tggatataaa atccattcat
    25081 tccaaagaaa tcaataaaga cctttcctag aaatacattc actggtggag tcatcaaaaa
    25141 aggtacaaaa agatagggat tcaaaataac tggcatacca aatagaagag gttcattcac
    25201 cgcaaataaa acaggagtaa ttgtagcttt acctaccgat tttaattgtt tagaccgcat
    25261 aaagaaaatc aaaataaatg gtacaacaaa ggtagccccc gttcctccga tagcagcgat
    25321 ataatttccg aaattaggcg ttaaagaatg ataaggaaac tgcccatttg caagaagttg
    25381 agcattctct tccatattgc tcagttgtaa agctgtaaca gcaggtaaga caatagatgg
    25441 tccatgaatt ccaacaaacc aaagcaaagc gcacataaac caaatcaaca tcatagcagg
    25501 atatgattct gcccccttaa aaataggagt caatagttgt tgaaatactt gggcaaaagg
    25561 aacatctaaa ctaaaccgag atacaatatc taacaaacca ctaataagta aaacaaaaga
    25621 aaaaggaaaa atatctctaa aagcttgtga tatagcccca ggaacttcct taggtaaatg
    25681 aatagtaatg tctcgcttaa tacagaatcg gtaaacattt acagtaataa aggtactgac
    25741 aaacgaagtt atcaatcctt gagatcctaa atagtttgtc gacaaacttg tagatcccgt
    25801 tttctcatca actacaagcg ttacagttaa tacaagatag ccacatatgg ccgccaacat
    25861 tgcagaagta tcatttatta cctttccagg aggcattttt ctattaacat ttccagccaa
    25921 tgactttgca actgtccctg aaacaataac acccaaaact cccatggtta gcatatacac
    25981 tttcctaatc caggcaatag ctggactcgg taactctact ccgaaatttt taggaatcat
    26041 aataataatc atcaaaaagc ttgaaaacat aattaaaggc atagtagcaa taaatccatc
    26101 tttaatagcc atcatataat tattagtaga aattttttca aatttccctt gttgcttttc
    26161 aatggcagcg actaacttat ccataaaaac tcctcctgta aaaaatttaa gctcatagtt
    26221 aaaatatatt aaacatcagt caaatcgcta accttaattc cgttttaatc cttttaccca
    26281 aagagcactt ttcttaatat atctcttctg tgtttcataa tcaacaaaga aaagaccata
    26341 tcgcttattg tagccattcg cccaagaaaa ttgatcttgc aaagaccata taaaatagcc
    26401 ttgaatattg actcccctat ctcgagcctc taaaactttg tgtaaatgtt gctcaatata
    26461 acggattctt ttactgtcat caataatatc attctcgccc tctggcttaa cctctttaag
    26521 ggctgtacca ttttcagtta aataaatgac cggatgttga ggatattctt ctttgatacg
    26581 aagcaacata tcaaataacc cttgaggata aatattccaa tcccaatctg ttgtcggaat
    26641 accaggcttt tttacaaatt cacctagagc atttaattta aaagaagact gtccttttat
    26701 tcctgttgaa ttaaattctt gtctattttc acctttgtat tcacgaataa attctgaacg
    26761 ataataattc atcccaaaca tcgtattaag aggtgcagct cttttcataa tttctaaatc
    26821 accatcttca ataataaagc tagaattatt agcttccaat atttgattca agtgaaaaag
    26881 cgtgtcatca ctgtagtagc ccaaaaaagt tccatctaat agaaatttat tattataaac
    26941 atcataccgt ttagctgcta aaatattttc tttttgccca tcaataggat agcctggctt
    27001 taaagcatga atacaaccta tctttccctc aatccctaat tgatgaaatt cgaggactgc
    27061 aagagcatgc gccaacaaca tattatgatt cgcttgaatt gcttcagata attgaaaatg
    27121 atgatttgga ggaaactgac ctcctatata ttgacctgca gcaagagaca tcagttcatt
    27181 gattgtaaac caatgcttga cttctgtaaa ttcttggaaa caaaagcgag catatcgtat
    27241 gaaacgatca atattctctc tattcaacca atcccctgtt tctaacattt tctgaggcga
    27301 atcaaaatga tgtaaagaaa caaacggaat cacattatgt tttaagcaag actgaaagac
    27361 tctatggtaa taacgaacag ctaatatatt aggctcccca tctatatcag gaaatatacg
    27421 aacccaagaa atagataaac gcaaagcctg caaaccatgt tctgccgcca aagctatatc
    27481 ctcttcgtaa cgataataaa aatcactagc tggatctggt aagaacggac tgttttcttg
    27541 caaataaaca tcccacatat ttgttccttt gccatctacc ctagttgcac cctctacttg
    27601 ataagcagcg gtagcagctc ctaataaaaa ctccttcggt aaggctttaa cctgtaaatt
    27661 ttccatgact aatcctcatt gcaaaccaat atgttcttca atctttcgaa ttcgttcata
    27721 ttcatcaata aaaaacttga cctgatcata caatagcatc gttgtcatca aagtatcttg
    27781 accatgaatc atgataaaac tcacttcaaa attatctcca gatgcctcct ccgctaataa
    27841 attagtctgt tctcgatggg cagacactat tgagtcgttt gcagactcaa ccaattctct
    27901 tgcctgttca aaatatccat ctctcgcaaa cgccaaagca tccatcaaat ctgaccttgc
    27961 atctcctgcg taagcgacaa ttgtaaaacc aagcatattt atttcttctt ttgatttcat
    28021 ctttcttcct cctcaatctt gatccatctt ttacacatca ttattaaaat gacttcgcta
    28081 cgatataaat agaaagtcga ccctaaatat cttaaaaatc cttaaatttc ataatattta
    28141 ggatcaatct tctctgaata ccttggttca ttttctatac ttatgattta taagtggaaa
    28201 ccagcgtaat tttttgctac ttcaattaca cgataaacat ccaaattaga ttggaatagc
    28261 agttcgtgcc cacggatata attcaacaca tttctccatt catcttgagc ttgccttgtt
    28321 tttccggttg cttgaagata taaagccttc gccatcttaa caacatattc acgatgataa
    28381 ctgagctgtt tccattcatc cttttgacta tttaataact tagaaatatt ttcctcaata
    28441 attggcaaaa aattatcagc tagattgtaa gctatataat aatgattcgc taaaacatca
    28501 ttttgacgac tgccaattgc attaaaataa tcacatgagg aataactgga taatttttct
    28561 aaatattcaa caacagactg ccaattttcc ccatacaaag cagaaaagta ttcttcaatc
    28621 aattcttcat aacttcttgt cttcttccag agcatttccc ccataacata attaggaaaa
    28681 ttatgaggga atccggcacg taattcttga cacgaaatgt aaccgttcaa atgtaggtta
    28741 gaaagataag atacatctct gtaaatggtt tgactaattt tcatatagcc taaatcgcca
    28801 taatgagcac gccctaaagg atagtcatat acgaaactat ctcctttaaa tgttttttgc
    28861 cactcaaaaa gataagataa attttcctca agagaattcg gaagtataat tttattacgc
    28921 agataaggtt taggcgtagg tatggaattg tcaaaatcta catctgcata actcatttca
    28981 aatgttcttg taatcggtgc aaacatcatg gtaaagcgtt caggattatc taatttttct
    29041 ttctgaggcg cccatagcaa ctcatggtaa agcagaaaac aaatctttgt atctaatccc
    29101 tcactcgtta aagccctatc caattgattg agaatacgaa tatactgatc cgaaaccaat
    29161 tcttgtctac agttttcgca ttcacaaata ttattacgag catccgacaa ccatacatgt
    29221 aagtagttaa catcaggtct tttcttggca taatccttga taatttctac catcttatcc
    29281 gccacatctg gatttgaaaa atccagactg gttaaaatcg gagccgtatt aaataattct
    29341 cgtttcccgt ttatttcagc gacatacggt ttctcctcct ctgaaatact aagacctgat
    29401 tcccagccaa attttgaaga gtaacctaaa acctcacctg tccatccatg accaacacga
    29461 tgatgaataa gacctctttt ttgcaattct ttatccaacc tatcactcaa ttcttgtact
    29521 aattcatttg agaatttttc tttatttagg tatggattaa actcatgttc ataccaacgt
    29581 ttcaaaaaag agtaaggatt ttcaaactgg atgaaaaaac tgttcatccc aatcttaggt
    29641 agccaatcaa tgaaatctag tatattttca aatgaatccg ctccctctat acatactccc
    29701 ctatgatagt aactggctgt ttcatctata gatagctgtt tatctaaaaa atcttcaaat
    29761 cgtaactctg gaacaaagtc atgtctgcgc cctggtctag tatacacaac cccaaattca
    29821 tgaaacattc ggtaaattcc aataagtaaa cctacaattg tattagactc aattctcccc
    29881 ttacccttgt ctaatgagat aagaacatgg tcttttctgt cctctttatt gactaatcct
    29941 acaaaaatat ccgcttcctt ctcctcgaca agctctatgt tagtcttaaa gacccgattc
    30001 atatagtaac ttaattcctc taaggcaaag ctagaataag tatttttctg ttgatcaaat
    30061 actctgataa ccatcttatt tccctccaac agtagctttt tctttttcaa gattgcgttt
    30121 atctgcaatt ttgaagaatg gataataaat tgctacagaa accaaaatca aaacaacttg
    30181 taatagagct cctcgccaac tagcccctgt tgcaaggaag cctcctataa tcggtggcat
    30241 tgtccacgga aggattacac ctgttgtata gggtactaat cctacagcca ttgatacata
    30301 ggtaatcaag gcattgattg taggagtagc aataaacgga atcagcataa tcggatttaa
    30361 aactgttgga aacgtaaata gaatagctgt attgatatta aaaatagacg gtataatagc
    30421 tagcttacct aatgttttat tcgcacgact cttactaaat aggaagagac aaatcgcaag
    30481 accaatagtc gctccaccgc caccaataaa tacaaataaa tctttaaacg gtaatgtaat
    30541 aatgtgttgg agtgtttgtc ctgcagccac agcttcttgg ttttctgtag taaattgtaa
    30601 ccaaactgag tctacaaaag catttaaaac ttgtccccca ttaactccac agaaccaaaa
    30661 gaatgagttt acaataacac atagaatcat acctggaagc gttcctgcaa ttaacttaag
    30721 cggtgttcca acaattgcac ctaggagtcc gttgagacct cctgcaactc ctgccgcttc
    30781 aagacctttt aagaccaaag cccacaaaac aaaagtagta aagccaggta aaagagctga
    30841 aaatgattta cttaccacat ctgggacacc acttggcatt tttatcgtaa ttccgcgctg
    30901 gataaacata cgataaatct ctgctgtaac caatccaata gtaatcgcca taaacaaaga
    30961 agatgcattc aggctagaaa atggtattgc gccgccaaat aactgcttga cctgctcccc
    31021 atttttatca taaaccatac tcgaaaaacg aggtgccatc aatacaaaac tggataaggc
    31081 tatgatccct gccgacggac catctgtacc atatccttcc gacaacctgt aggcaatacc
    31141 gaaacaagcg accaaggaga taatcgctac tgttgactga ttcatagttg tcaagatact
    31201 tagcaatcca acactattca gccaatttgt aaaatcctct tgaggccaac tgattagaat
    31261 aagaaataaa gatccgacta aaatcaaagg cattgccatc ataaatcctt cacgaatagc
    31321 tttcaaatgc cgttggttgc caactttttc accaaacgga gcgacttttg tttctaaaaa
    31381 cgctaaaata ttgttcatca ccggaactcc tttttttatt ttttataaat taaatatacc
    31441 actaacagaa agcgttgtca atatattttt tgttgttttt acaatatttt tttctttgta
    31501 tagaataata attttaattg attttttctt atgtttaata taaaataaac caaaggagga
    31561 aacaaatgat tacaaaacaa tcagcctttt tacaaaatag agccactata ctggagtttc
    31621 tatatcgaaa tccagcaaca tcccgtacag atattgttaa tgaaacagga cttactccag
    31681 caacaacgac taacatcata aaagagctaa gcgaacagtc cctcatatac gaaactggtg
    31741 atgaatttag cgagttttcc ggatctggaa gacgtagaaa aactatttct atcacagata
    31801 atattccgta tgttgttgga ggtattgaaa taaacgtcct aggtatcttt ctcagtctat
    31861 gtgacttaca agggaaaact cttttcgaga cagaaatttt gaatgaagat tatcctattt
    31921 cagaaatcaa ttccaccatt accaatatga taaaaacagc tatagagtac gtccctttgg
    31981 aaacaaaatt acttggattt ggcttatcaa tacctggaca ttataacaaa gactccggaa
    32041 gtatcattac aaacaacccc atatgggaat cttttaattt attaaatgta attaaaagat
    32101 tcaattttcc ttttattgta aaaaataata tcgattgtat ggctatagga caataccttt
    32161 ttaatccaca caataccccc gataacttta ttttcctaca cgctggatta ggtatttaca
    32221 cttccttttt cacaaaagaa aaaataggag cctctaaaaa tccttatatc ggagaaattg
    32281 gacacaccat tgtcgaattg aatgggcaat attgtgaatg cggaaaaaaa ggttgtttac
    32341 aaacatatat ttcggatgct tggttaatca aacacgccca attattattt aaaaattccc
    32401 aactaactgt actaaaaagc cttgtaaaga ctgaaaaaga cattcattta gacacccttt
    32461 taacggctta taatttaggc gactccgctt tacgtcaaca aattgataaa ggagtcaatt
    32521 tattagccac ttctattgca aatctcctcc tcatcaatcc tgctgataaa atctatatca
    32581 acagtcaatt gcttaattat caacctttca ctcatgaagt cagggataaa atccaagacc
    32641 agctccactt cgttcccttt actcgtaata tagaaattga aattttacct tacaacaaac
    32701 atcgtggaag tataggagct tgtgcattag ctatcgtcgc ttttttcata gaacatagca
    32761 atgtattaca agatattatt tcaccttaat atattagaaa tctatagacc tgtttaaatc
    32821 aactataacc tgtagtagat atctcgtatt tagacaatat gaaaacaaga cgacttccat
    32881 ataggaaacc gccttctcgc tatgttgagt gatttatatt aaaataactt ttcttctagc
    32941 tgcattttat tattataaaa acattcatca taacccccag aacttaaata acaattttta
    33001 ttcaagatac atactcctag aataaacttt atatgaaatt ctcatttttg tttttacaat
    33061 tctccttagt taaatcttgt ttaatatatg ttttacatat agtatttagc gccacatagt
    33121 actgaactct ctccaaaaac ggttattcct ctttgaatag ggcgttatca caagaaaagc
    33181 atctccacgt ttcaacttca tatggctcaa aaacaatcaa ttgatgctaa aacctgtacc
    33241 tagatgtttc ggttcataaa accatgaaac tgtaaaagtg gatgaaattg atagcgatag
    33301 tcaaatcaag aggcatcata actctaaaaa gtcacaatat ataagttcat cctcggaaaa
    33361 atatcattct aattgttgaa atgcctacat gaaaagaaac gtcaaatgct catgaaacaa
    33421 cgaatacagg tatcaaaact atgacaaaac aagtccctaa atttactaaa gacactgctc
    33481 aactttacac ctgtaaatgg ttgttgtata ataaagttac aaagatgtac gaccacactg
    33541 ttgtaaatca tagtgttcgc gaatatatta ctgatagcat ttctacaaat acaattgaaa
    33601 aggctggata ggctttaaac gaaatatgtc agtgttttgg cattcctagc cttcatatca
    33661 tttaaagaat tgtatagaca aaatttttcc caatacagac actcgtaaca actgcttcat
    33721 ttttctacca acatatttag gaacaggata agatacaaga ggattaatcc atagatcagt
    33781 tctataccaa tctaagacaa ataagctaaa aaaacgattg ataataagca aatagattcc
    33841 aaattttctc tatctgctca ttttaataaa caatactagt gtaactatcc ttccagtcag
    33901 aagcttgtca aatcacaccg aaaattcttc taaaatttat ctcgttaggc aatcaagcaa
    33961 aaactcgacg atagtacaaa cattatcata cagaattgac ttcctaaatt atatacttta
    34021 gtaatgtttt cggataagaa aaaagattca ttttacattt ctaaacattc ttttctaaga
    34081 tgaaaaacag aatttttcga ttgtgattta aagcaacaag aagattttca gtatcatcct
    34141 atagatacga gctaattaag aaaaactaca ttttcgaata taaactacaa taatataaac
    34201 taaattttat aggaggaaga caatggattg gtacgattat atgatacagg catccaaaca
    34261 atcacaattc aacgcaagcc attggtttcg ctatttgcga aaagttattt ttgaagacta
    34321 ttcttattta acaaaccaag atgtagaaaa gttgctagac tccaaagaac taacccgttt
    34381 tcaaaaaatt agcttgaagt atgcctttca agagcatact ccaactcata aatatgtgat
    34441 ttcattaaat aaacctgcta agttaaccaa tgttcaaaaa ttgatggaga aatacaaaca
    34501 tggataaaat gaaaccggtc ttccaagccc taaataagga attaattcag gaaaatctga
    34561 ctttaacaat tatctgtgtc gatggttatg tcttagaata tcatggttta cgtgccacac
    34621 aagatgttga tgcttttatg gctctataat atttgtagtg ggtaaatccc ctatggatat
    34681 tatggagcct a
//
LOCUS       DBEROT010000022        34010 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.22, whole genome shotgun sequence.
ACCESSION   DBEROT010000022 DBEROT010000000
VERSION     DBEROT010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34010
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.22"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..411
                     /locus_tag="ACL8CG_001196"
     CDS             <1..411
                     /locus_tag="ACL8CG_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS1343794.1"
                     /translation="WLQYNDSWYYLNASGAMATGWLQYNGSWYYLNANGSMATGWLQY
                     NGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQW
                     FKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            812..1933
                     /gene="mnmA"
                     /locus_tag="ACL8CG_001197"
     CDS             812..1933
                     /gene="mnmA"
                     /locus_tag="ACL8CG_001197"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGS1343795.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2074..2529
                     /locus_tag="ACL8CG_001198"
     CDS             2074..2529
                     /locus_tag="ACL8CG_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1343796.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWKGQLRHIHLEK"
     gene            2539..4452
                     /gene="mnmG"
                     /locus_tag="ACL8CG_001199"
     CDS             2539..4452
                     /gene="mnmG"
                     /locus_tag="ACL8CG_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGS1343797.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4831..6510)
                     /locus_tag="ACL8CG_001200"
     CDS             complement(4831..6510)
                     /locus_tag="ACL8CG_001200"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS1343798.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQGEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6512..6745)
                     /locus_tag="ACL8CG_001201"
     CDS             complement(6512..6745)
                     /locus_tag="ACL8CG_001201"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGS1343799.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7025..7238
                     /locus_tag="ACL8CG_001202"
                     /pseudo
     CDS             7025..7238
                     /locus_tag="ACL8CG_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7561..7713)
                     /gene="cibB"
                     /locus_tag="ACL8CG_001203"
     CDS             complement(7561..7713)
                     /gene="cibB"
                     /locus_tag="ACL8CG_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGS1343800.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7715..7900)
                     /gene="cibA"
                     /locus_tag="ACL8CG_001204"
     CDS             complement(7715..7900)
                     /gene="cibA"
                     /locus_tag="ACL8CG_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGS1343801.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8078..8761
                     /gene="tsaB"
                     /locus_tag="ACL8CG_001205"
     CDS             8078..8761
                     /gene="tsaB"
                     /locus_tag="ACL8CG_001205"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGS1343802.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKNLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYVGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8758..9195
                     /gene="rimI"
                     /locus_tag="ACL8CG_001206"
     CDS             8758..9195
                     /gene="rimI"
                     /locus_tag="ACL8CG_001206"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGS1343803.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVIAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9185..10195
                     /gene="tsaD"
                     /locus_tag="ACL8CG_001207"
     CDS             9185..10195
                     /gene="tsaD"
                     /locus_tag="ACL8CG_001207"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGS1343804.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10235..11541)
                     /locus_tag="ACL8CG_001208"
                     /pseudo
     CDS             complement(10235..11541)
                     /locus_tag="ACL8CG_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11877..12568)
                     /locus_tag="ACL8CG_001209"
                     /pseudo
     CDS             complement(11877..12568)
                     /locus_tag="ACL8CG_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12811..13131
                     /locus_tag="ACL8CG_001210"
     CDS             12811..13131
                     /locus_tag="ACL8CG_001210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343805.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMFLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKI"
     gene            13174..13365
                     /locus_tag="ACL8CG_001211"
     CDS             13174..13365
                     /locus_tag="ACL8CG_001211"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1343806.1"
                     /translation="MLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWTYSMGD
                     AFICVSETMKKRLESIIKK"
     gene            13493..14017
                     /locus_tag="ACL8CG_001212"
     CDS             13493..14017
                     /locus_tag="ACL8CG_001212"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1343807.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNIGGLS
                     EIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVET
                     MRVYDELLEKSSHG"
     gene            14010..14963
                     /locus_tag="ACL8CG_001213"
     CDS             14010..14963
                     /locus_tag="ACL8CG_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1343808.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFPFLEYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            14973..16589
                     /locus_tag="ACL8CG_001214"
     CDS             14973..16589
                     /locus_tag="ACL8CG_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1343809.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKRIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16849..17277
                     /locus_tag="ACL8CG_001215"
     CDS             16849..17277
                     /locus_tag="ACL8CG_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343810.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17289..18038
                     /locus_tag="ACL8CG_001216"
     CDS             17289..18038
                     /locus_tag="ACL8CG_001216"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGS1343811.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            18051..19223
                     /locus_tag="ACL8CG_001217"
     CDS             18051..19223
                     /locus_tag="ACL8CG_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGS1343812.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPFGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            19619..20482
                     /locus_tag="ACL8CG_001218"
     CDS             19619..20482
                     /locus_tag="ACL8CG_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS1343813.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            20768..20968
                     /locus_tag="ACL8CG_001219"
     CDS             20768..20968
                     /locus_tag="ACL8CG_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HGS1343814.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            21035..21700
                     /locus_tag="ACL8CG_001220"
     CDS             21035..21700
                     /locus_tag="ACL8CG_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1343815.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            21772..22998
                     /locus_tag="ACL8CG_001221"
     CDS             21772..22998
                     /locus_tag="ACL8CG_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1343816.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            23404..25305
                     /locus_tag="ACL8CG_001222"
     CDS             23404..25305
                     /locus_tag="ACL8CG_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1343817.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            25308..26171
                     /locus_tag="ACL8CG_001223"
     CDS             25308..26171
                     /locus_tag="ACL8CG_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS1343818.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            26251..27429
                     /locus_tag="ACL8CG_001224"
     CDS             26251..27429
                     /locus_tag="ACL8CG_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1343819.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVCLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFFPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSLSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            27522..29480
                     /gene="ligA"
                     /locus_tag="ACL8CG_001225"
     CDS             27522..29480
                     /gene="ligA"
                     /locus_tag="ACL8CG_001225"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGS1343820.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRSLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            29592..31871
                     /gene="pulA"
                     /locus_tag="ACL8CG_001226"
     CDS             29592..31871
                     /gene="pulA"
                     /locus_tag="ACL8CG_001226"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGS1343821.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            32415..33839
                     /locus_tag="ACL8CG_001227"
     CDS             32415..33839
                     /locus_tag="ACL8CG_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS1343822.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
BASE COUNT        10365 a         5875 c         7309 g        10461 t
ORIGIN      
        1 tggctccaat acaacgattc atggtattac ctaaacgcta gcggcgctat ggcaacaggt
       61 tggctccaat acaacggttc atggtactac ctcaacgcta acggttcaat ggcaacaggt
      121 tggctccaat acaacggttc atggtactac ctcaacgcta acggcgctat ggcaacaggt
      181 tgggctaaag tcaacggttc atggtactac ctcaacgcta acggttcaat ggcaacaggt
      241 tgggtgaaag atggagatac ctggtactat cttgaagcat caggtgctat gaaagcaagc
      301 caatggttca aagtatcaga taaatggtac tatgtcaatg gtttaggtgc ccttgcagtc
      361 aacacaactg tagatggcta taaagtcaat gccaatggtg aatgggttta agccgattaa
      421 attaaatcat gttaagaaca tttgacattt taattttgaa acaaagataa ggttcgattg
      481 aataaattta tgttcgtatt ctttaggtac ctatcttatg atttcaggaa atgtcattaa
      541 aaaaacgact ccttttctct aacttgaaaa atagattaga gaaaatgggt tgttttattt
      601 attatagtta tttgaatgaa gataagaaga aggtatactc acatcattca cataatctgt
      661 atattgacta taagttttaa aaaacaattt ttaagctctt ccttgtcttc tctaaccaag
      721 cgtgttataa tgaatactgc tcaagcgacc ttcaatcgtg aagcacacac gaccttcaat
      781 cgtgaataaa cgaatagatg ggagacttac catgagtgat aactctaaaa cacgtgttgt
      841 cgtggggatg agtggtggtg ttgattcgtc ggtgacggct cttttgctta aggagcaggg
      901 ctacgatgtg atcggtatct tcatgaagaa ctgggatgac acagatgaaa acggcgtttg
      961 tacggcgacc gaagattaca aggatgtggt tgcggtggca gaccagattg gcattcccta
     1021 ctactctgtc aattttgaaa aagagtactg ggaccgcgtt tttgagtatt tcctagcgga
     1081 ataccgtgca gggcgcacgc caaatccgga cgttatgtgc aacaaggaaa tcaagttcaa
     1141 ggcctttttg gactatgcca tgaccttggg ggcagactat gtagcgactg ggcattatgc
     1201 tcgagtggcg cgtgatgagg acggcactgt tcacatgctt cgtggcgtgg acaatggcaa
     1261 ggaccagacc tatttcctca gccaactttc gcaagaacaa ctccaaaaaa ccatgttccc
     1321 tctgggacat ttggaaaagc ctgaagtacg cagactagca gaagaagcag gcctttcgac
     1381 tgctaagaag aaagactcga cagggatttg ctttatcgga gaaaagaact ttaaaaactt
     1441 tctcagcaac tacctgccag ctcagcctgg tcgtatgatg actgtggatg gtcgcgatat
     1501 gggcgagcat gctggtctga tgtactatac aatcggtcag cgtggcggac tcggtatcgg
     1561 tgggcaacac ggcggtgaca atgccccttg gttcgttgtt ggaaaagatc taagcaagaa
     1621 tattctctat gtaggacaag gattctacca tgattcgctc atgtcaacta gcctagaagc
     1681 cagtcaagtc cactttactc gtgaaatgcc agaagagttt acgctagaat gtacggctaa
     1741 attccgttac cgtcagcctg actctaaggt gaccgtccat gtcaaaggag acaaggcaga
     1801 agttatcttt gcggaaccac aacgcgcgat tacaccagga caggcagttg tcttttacga
     1861 tggcgaagag tgtctaggtg gcggtttgat tgacaatgct taccgcgatg gacaagtttg
     1921 tcagtacatt tagattgaca aattttctca atttgctaca ataataacag caatagaaat
     1981 gatggtcaaa gctcatggat gttgcaggct tttttgtcct gcacttcttt gtagttttga
     2041 ctgtttttgt gtcgtttaag ggaaaggaca agaatgactc aacaagactt tcggacaaaa
     2101 gtagacaata cggtttttgg tgttcgggct acagccttga ttgtccaaaa tcacaagctt
     2161 ctagttacca aagacaaggg caagtattac actattggag gtgcgattca agtcaatgaa
     2221 agcacggaag acgcggtagt ccgtgaagtg aaggaagaac tgggtgtcaa agctcaagct
     2281 gggcagctag cttttgtggt tgaaaatcgt tttgaacagg acggtgtttc ctatcacaat
     2341 atcgaatttc attatctggt agacttactg gaggatgccc cattgaccat gcaggaagat
     2401 gagaaaaggc agccctgtga gtggattgac ttggataagc ttgaggatat ccagctagtt
     2461 ccagcctttt taaaaacggc cctaccagat tggaaaggcc aactaagaca catccatctt
     2521 gagaaatagg agagaaatat gacatatcat tttactgaag aatacgatat tattgtaatt
     2581 ggtgcgggac acgctggggt tgaggcttcc ttggccgcta gccgtatggg ctgtaaggtc
     2641 ctgcttgcga ccatcaatat tgaaatgctg gctttcatgc cttgtaatcc ctctatcggt
     2701 ggttctgcta aggggattgt cgtacgtgaa gtcgatgccc tcggtggcga gatggccaag
     2761 accattgaca agacttacat ccagatgaag atgctcaaca cagggaaggg gccagccgtt
     2821 cgtgcccttc gtgcgcaggc tgacaaggaa ctttactcta aggaaatgcg caagacagtt
     2881 gaaaaccaag aaaatctgac ccttcgtcaa accatgattg atgagatttt ggtggaagat
     2941 ggcaaggttg tcggtgtgcg tacagccacc catcaagaat atgctgctaa ggctgttatt
     3001 gtgacgacag ggactgctct ccgtggggaa attatcatcg gagacctcaa gtactcatca
     3061 ggtcctaacc acagcttggc ttctattaac ctagctgata atctcaagga actgggcctc
     3121 gaaatcggtc gtttcaagac aggaacccct ccacgtgtca aggcttcttc tatcaactac
     3181 gacgtgacag aaatccaacc aggagatgaa gcgcctaatc acttctcata cacttcacgt
     3241 gatgaggatt atgtcaagga ccaagtgcca tgctggttga cctacaccaa tggtaccagt
     3301 catgagatta tccaaaacaa cctccaccgt gcgcctatgt ttacaggtgt ggtcaaggga
     3361 gtggggcctc gttactgtcc gtcgattgaa gacaagattg tgcgctttgc ggacaaggaa
     3421 cgtcaccaac tcttccttga accagaaggg cgcaatactg aggaagtcta tgtgcaagga
     3481 ctttcaacca gtctgcctga ggatgtccag cgtgacttgg ttcattccat caaaggtttg
     3541 gaaaatgcag agatgatgcg gacaggttat gctattgagt atgatatggt cttgcctcat
     3601 cagttgcgtg cgactctgga aaccaagaaa atctcaggtc tcttcactgc tggtcagaca
     3661 aatggaacgt caggttacga agaggcagca ggccaaggga ttatcgcggg tatcaatgcg
     3721 gctctgaaaa tccaaggtaa gcctgagttg attttgaagc gaagtgacgg ttatatcggg
     3781 gtgatgatcg acgacttggt gaccaaggga accattgaac cttaccgtct cttgaccagt
     3841 cgtgctgaat atcgtctcat tcttcgccat gacaatgctg atatgcgctt gactgagatg
     3901 ggacgcgaga ttggccttgt ggatgatgaa cgctgggctc gttttgaaat caagaaaaat
     3961 caatttgata atgagatgaa acgcctagac agtatcaaac tcaagccagt caaggaaacc
     4021 aatgctaagg ttgaggaaat gggcttcaag cccttgacag atgcggtgac agccaaggaa
     4081 ttccttcgcc gtccagaagt ttcttaccaa gatgtggtgg ccttcatcgg accagctgca
     4141 gaagacttgg atgacaagat tatcgaattg attgaaacag aaatcaagta cgaaggctat
     4201 atttcaaaag ccatggatca ggttgccaag atgaaacgta tggaagaaaa acgcattcca
     4261 gccaatattg actgggatga cattgactct atcgcaacag aagctcgtca gaagttcaaa
     4321 ctcatcaatc cagaaaccat cggccaagcc agccgtattt cgggagtaaa cccagcagat
     4381 atttctattt tgatggtgta tctggaaggt aaaaatcgta gtatttctaa aactcttcaa
     4441 aaatcaaaat gatacgtcgt tggcttctta cgaatgagtt caaagcttgg ctttgattca
     4501 tctccagcct cccatagttt cccgaactat gggagctaac tcaagttatg cattttccta
     4561 gccttctggt ctgattttca ttgagtttta atctcaaaag aaagcataga gaaaaacagc
     4621 tccgaagacg gggctgtttt gttgacttgt actcaatgaa aatcaaagag caaactagga
     4681 agctagccgt aggttgctca aagcactgct ttgaggttgt agatagaact gacgaagtca
     4741 gctcaaaaca cagttttgag gttgtggata gaattgacga agtcagtaac atatatacgg
     4801 caaggcgaag ctgacgtggt ttgaagagta ttattcttca tctggtgtga ggatcatcgg
     4861 gatgatgatc ggttcacgtt cggtattttc atagaggaag gggcgaatag cgttgacaat
     4921 ggcaccattg acagattgca cgctagcatc cttatttttc agtgcgatac gaatggcatt
     4981 gaagaggata cgctggcttt ggcgaatcaa gtcgccagac tctctcatgt agacaaagcc
     5041 tcggctgagg atgtctggac cagatagaat catctgcgat ttgaagtcaa cagttgcgac
     5101 tgccagaacg acaccgtctt cagatagatc gcgacgatct ttgaggacag ctgcgccaat
     5161 ttcaccgata cgatttccat cgacatagat atcttgggcg ttgaaatgac ctgcgatacg
     5221 agctgagtca gcagtaaggg caagcacatc gccattgctc atgataaaga tattgtcctt
     5281 ctcaacacca gtatccactg ctagtccagc gtggactttt tgcatgcggt attcaccgtg
     5341 gacaggcatg aagtattttg gcttaatcaa gcagagcatg agtttttgct cttgctgacc
     5401 accgtgtcca gatgtatgga tattgttcac tttaccgtgg ataacttcga caccagcttc
     5461 agaaatgatg ttaatcagct tgttgacgct agtagtgttt ccagggatgg gactagaaga
     5521 gaagataacg gtatcacctg gttgtaattg tacttgacgg tgggttccgt tggcgatacg
     5581 agagagggct gccataggct caccctgact acctgtacag aggataagaa cttctcctgc
     5641 aggataatct ttgatttcat ttggctcgat aaaggttccc ttaggagctt tgatgtagcc
     5701 aagatcgatt ccgttgacaa tggccttttc catagaacga ccaaagaccg caatcttgcg
     5761 tccagtctta acagcagctt ctgttgcctg ctggagacgg aagatatttg aggcaaagga
     5821 tgcaaagatg atacgtcctt caataccttg gataatcttc ataatggact gaccaacgac
     5881 tttttcagag ttggtaaagg ttggtacttc cgcatttgtc gagtcagaca ggagacagag
     5941 cacgccttct tcaccaagcg cagccatacg atgcaagtcc gcaggttctc caactggagt
     6001 aaagtcgaac ttaaagtcac ccgtacagac gattttccct tgaggagtat gaatgacaat
     6061 ccccaaaggc tctggaatag agtgagtcgt tctaaagaaa gttgccttga gatttttaaa
     6121 ggtcaactcg gtgttgtggt tgatttcgta aagtttggcg ttgcgcaaga ggccgtgttc
     6181 ttcgagtttc ccacggatca aagccaaggc aagcggtcca gcgtagatag ggacatttgc
     6241 ttgcttgagt aggaacggaa tcccaccaat gtggtcctcg tgtccgtgtg tgattaaaac
     6301 agccttgacg cggtcgatat tgtccacgat gtaagagtag tcaggaatga catagtcgat
     6361 accaagcaag tcatcttctg ggaatttaat cccagcatcg acgatgataa tctcgccttg
     6421 gtattcaatt ccgtaagtgt ttttcccgat ttctcctaga ccaccgatgg caaaaacgcc
     6481 gacttcttca ggtttaagag tgtaggccat attagaactc cgtaatttcg aaggcgccag
     6541 tttctttttc gtaatcgagc aatttgtcag acaagagttc gatatattcg atattgtact
     6601 ctgggcgatt ttcttcgaca agttggcgag cagtgatacg gccctcaagt tctgagctgg
     6661 catcgatgtc taggtaaagc gcgcgtgttg tttcacggcg tgggctacgt tcttttgttt
     6721 cttgataaaa aactttgtaa atcatatagt tcctttctat ttacaggtca gcttattcca
     6781 aacttttagc agatatttgc ttgatttcat tccattttgt gtctagattg accttgattc
     6841 gttacaatta tttcaattat accacaaaat gaaaaattag taaaagacgg aaacgagaaa
     6901 gttaggggac gatttcttcg gtaagcgttt gcgaaaataa agaaaatgta ttatgttgat
     6961 aacggaagtg aaatttattg cttgtcataa ttccatatag attttaagtc aaggaggttg
     7021 ccctatgtat aacttatttg cttttgctat cggagttcgt ttgctagctt ttatcgtttt
     7081 tgttttgcgt ttatggagga aatcttctat ttgccaaact ggaacgatga caaaccaagt
     7141 tcttgaggaa aattaccttt gtgactctct actcgctttt tctcctcctc gtgacctatg
     7201 tcgtttggtt tgtattttac tttggattaa atgcttagat gccctgctta tgctggggtt
     7261 ttttgtttgg ggatgtagag atagtagatt tacgacacga aaattccacc ccatctatca
     7321 agatgaggtg gtctttgcat ttttctaaaa tgatatgaca atggaatttt caaagcttat
     7381 tatttttatg ggagtcattg ttctgctcaa aaatagagtt gaagcataaa aataaaacaa
     7441 tacaaacaga taaatcgaat ggtaaaggga tggtagtaat gttcaaatca ttgagaatgc
     7501 tgagcaaact gtaagagatg aagacaataa aatttatcct tctaaaaatg tgtttcttat
     7561 ctagcatgac ttaccaaact ttttacgaag gtcttttcca atggtataac ctgccataaa
     7621 taaagcgata ccaacaccta caccaaagcc acccttgatt tcttgcaatt ccttattaga
     7681 aatttcacga cagttgttca aatctttcat catattaatc tcctcctaaa aaataaccag
     7741 ctgccaaacc agaacctata agtgctgttc cacctgcaat agctttccaa gatactgcta
     7801 ctccaaagat aaccaaggga gcgagaccgc catcaatatc tgataattca ttttcagata
     7861 aggataaaaa ttgattgtca agaatgtcaa aatttgtcat tgaactttcc tccttttttc
     7921 ttgttcactt ttatattcgg aaaagaaaag gaaaagtgag cattttttta aattattttt
     7981 agttaagtga gggcactctt gtctgggggc aaagaaaatt cccatgtgcc agcttttgta
     8041 gtataatagt aagcagacaa aaagatagga atgtgttatg aaagtattag cttttgatac
     8101 gtccagcaag gctctttctc tcgctatttt agaggacaag caggttcttg ccgagacgac
     8161 gattaatatt aagaaaaatc acagtattac tcttatgcct gccatagatt ttttgatggc
     8221 aagtttggat tggacaccca agaatttgga ccgaatcgtg gtagctgaag ggccgggtag
     8281 ctacacaggc ttgcgaattg cggtagccac tgccaagact ttggctcata ctctgaacat
     8341 cgagttagtt ggtatgtcta gcctcttggc tctggtaccc taccaacaag aaggcttgtt
     8401 cgtctctttg atggatgcgc gtcgcaacaa tgtttatgta ggattttatg aaaatgctaa
     8461 acccgtcatg ccagaagctc acttaccctt tgagcgagtg attgagttaa tcaagggtgc
     8521 tagtcaggtt acctttgtcg gagaagttgg cccctttgtt gagcagattc aagaatactt
     8581 gccaaggact aatttcaaag aaaccttgcc aaatgcagct aatctagctc tatgggcctg
     8641 ggacaaggaa gcagactcct tgcatgattt tgtgccgaat tacctcaaac gagtcgaggc
     8701 tgaggaaaac tggctcaaga accataccga gtctggtgag tcctacatta aacgcctatg
     8761 atagaaatca agcgaattca acaacagcct gacctagctc aagccatcta cgctgttata
     8821 gcagctgttt acctagtcag tccttggact ctggagcaaa tccaagcaga tctgtcccaa
     8881 gaccagactt ggtatgcatt ggcttatgat ggggcagaag tgattggatt tctagctgtg
     8941 caggagaatc tttttgaagc agaagtcctg caaatcgctg tcaaaggagc ctatcagggt
     9001 cagggaattg cgtcagcctt gtttgctcaa ttgccgacag ataaggagat tttcctcgaa
     9061 gtcagaaagt caaatcaacg agcgcaagca ttttacaaga aagaaaaaat ggcggtcatc
     9121 gctgagcgaa aggcctacta ccatgaccca gtcgaggacg ccattatcat gaagagagaa
     9181 atagatgaag gatagatata ttttagcatt tgagacatcc tgtgatgaga ccagtgtcgc
     9241 cgtcttgaaa aacgacgatg agctcttgtc caatgtcatt gctagtcaaa ttgagagtca
     9301 caaacgtttt ggtggcgtag tgcccgaagt agccagtcgt caccatgtcg aggtcattac
     9361 agcctgtatc gaggaggcat tggcagaagc agggattacc gaagaggacg tgacagctgt
     9421 tgcggttacc tacggaccag gcttggtcgg agccttgcta gttggtttgt cagctgccaa
     9481 ggcctttgct tgggctcacg gacttccact gattcctgtt aatcacatgg ctgggcacct
     9541 catggcagct cagagtgtgg agcctttgga gtttcccttg ctagccctct tggtcagcgg
     9601 cggacacaca gagttggttt atgtttcgga ggcaggagat tataagattg ttggggaaac
     9661 ccgtgatgat gcggttggtg aggcttatga taaggtcggc cgtgtcatgg gcttgaccta
     9721 tcctgcaggt cgtgagattg acgagctggc tcatcagggg caggatattt atgatttccc
     9781 ccgtgccatg attaaggaag ataatctgga gttctccttc tcaggtttga aatctgcctt
     9841 tatcaatctt tatcacaatg ccgagcaaaa gggagaaagc ctgtctacag aagatttgtg
     9901 tgcttccttc caagcagcag ttatggacat tctcatggca aaaaccaaga aggctttgga
     9961 gaaatatcct gttaaaaccc tggttgtggc aggtggtgtg gcagccaata aaggtctcag
    10021 agaacgccta gcagccgaaa tcacagatgt caaggttatc atcccccctc tgcgactctg
    10081 cggagacaat gcaggtatga ttgcctatgc cagcgtcagc gagtggaaca aagaaaactt
    10141 cgcaggctgg gacctcaatg ccaaaccaag tcttgccttt gataccatgg aataaagagt
    10201 ggctctttgt caagtgtagt gggtaggcga aaagctacaa tctggagagt acgaaattcg
    10261 tactctcttt tttgatgttc aaagtcatca aaatccgttt tttaaaattg ttaaagttcc
    10321 ggaaaccaaa ggctttgcgc ttgataatct taatcaaatt attggtcgct tcaagtttag
    10381 cgttggaata aggcagctta agtgcgttga taatcttatc tctatctctt aaaaaagtcc
    10441 aaaagaccgt ttgaaaaagc ggatgaaccg ttggcagttc ttgctcaatc aatccaaaga
    10501 aatggtcggc attcttctct tgaaaatgaa agagcaggag ttgatagagt tcgtagtgaa
    10561 cctgtaatcc ctcagagtaa gacagcagct tatctcgtac ttcccgatgg gttaagtgca
    10621 ttcgaaacgt gggctgatag aatcgtttct gacagagctt gaagctatac tggtgtagta
    10681 aatcagtcca gtggactgat ttagcccgag cctagaaacg aaaaagcgag ggttccaaaa
    10741 gcgcttgagc gcccgatact ccaaggattt tcggtcaaat tggttcatga tttggattcg
    10801 tactcggttc atagctcggc tcagatgttg gacaatgtgg aagcggtcaa gaacaatctt
    10861 cgcctttgga aagagttgct tagcgagccg ataataaggg ctgtacatgt ccatggtgat
    10921 gacctcgacc agctcccgaa cctctctctg atagcgttgg aaatggtttc gaatcaccgc
    10981 atgagttcgc ccgtctaaaa ttgcgaggat ggatttggac tcaaaatctt gggcaatgaa
    11041 gctcattttg ctctttttga agctatactc atcccaactc ataacttttg gcaacttggt
    11101 ccaatcggtt tcaaacttaa attccctcag ttttcggatg acggtggaag ttgagaccgc
    11161 caatctgtgg gcaatctcag tcatagactg cttttcaagg aggagctgag cgattttttg
    11221 tctcaccatg ttggaaatct ggcaattttt cttgacaatg gatgtttgag aaacgaccac
    11281 cttaaggcaa ttcttgcact gaaagcggcg ctttttgaga tgcagtaccg tgggtaaacc
    11341 ctgacagtcg agaagcggaa ttttagaggc tttctggaag tcgtatttga tcatcttccc
    11401 ttgacaatga ggacaaggag gagcggggga atccaacttt gcctgaacga ctagatgggt
    11461 ttggtatttc agaacagaca agattttgat atttttgtct tccaatccga gcaaatctgt
    11521 ggtattctta agttgttcca tatgacccct ttctaatgag ttggttagac gcttttcatt
    11581 ataggtcata tggggctttt tttctacaag aaacgaccct ataattcctg gggtgggatt
    11641 acccactaca gaaattatag agccaaaaca ttccaaagta ttgtctgact ctggaatgtt
    11701 ttctgttcac agttgttttg taactgccta ataagtaacc gcgctataac gaggtatcta
    11761 ccgagattgt caattctcca gtatactgtt ataaaaaaca aaactggagg atttttttat
    11821 gtccccccat cgtcccatcg actgttccgt agctgcccaa taacggagta tagtcggctg
    11881 aaacaagaat aggacaaaag tacctcaaga aaagcatcgt aatttgacaa tattattctg
    11941 agatgttttt gatgtaagcc catattttct caatgggatt atactcgggt gaataggtag
    12001 gaagtggtag cagtctatgc cctgctcctt acacatgttc attctgtgaa accttgcatt
    12061 gtccataatg ataagggatg gtgtatctaa agtaggtagt aagaattttt ggaagcaagc
    12121 ttcgaaaaag tcactcgtca tcgtatcttt ataggtcatc ggagccatag tatattgaaa
    12181 caaaaaaggg cattagtact tctataacag tatcgcaatc tctggtgtgc gttgtctcga
    12241 tcttaattca aataattata tcttcttcca gagagactaa ctgcctgctc aaggctcgat
    12301 catattcgag ataaaaatag gtctcaaccc ctgtctcata aatataaata ggagtcaggt
    12361 agcttaagtg attcaattct ttaaggaacc gatttacttt ttctgggtct tgttcgcagt
    12421 aggtacggct cttttttaga ctatatccca tagcctttag agcgtaatga atagttgttg
    12481 gaggacagtt gaattcagca gctatttcag tcaaataagc atcgggatga gtttcaatat
    12541 agatctttaa tttatctcta tcaacttttt caattaatag tggaagtttt cttaaagtta
    12601 gtgtgttgaa acgtttttat acagtgctaa aatttgaagt gtagtgcaga tgtatttgta
    12661 atagtattat agcaattctt tggagaaggt cgagacaaga gaaaataggt atctttgaga
    12721 tataagcatg atttactata aaattattga gttattcata aaaatttctc tatcaaatat
    12781 cataatgcgt cgtttaagga gatggttaca atgcaatata gttgtggaaa aataaatatt
    12841 aatatccctg atggatatgg agacattaag gatatagtgt tttcggctca tattatagtt
    12901 aggtataata atggacattg tggaggtata gatccgcata taattggact ttgtaaaaag
    12961 cagatcagaa ggatgtttct atatcctatt ttgataatcg tatctagaga ttcaaaggtt
    13021 attgatgatt ataaaaattt agatattgcc tatgttgatt gtactcaatg ttcaaataat
    13081 tttgaaactg ccttacacgt taaaaatatt ttaaaattat taaaaatcta acttatacac
    13141 tgtcatggct actcaactaa ttatttttta tatatgttaa aaaaacttga caagaatgga
    13201 tttggaaagg ttaagacagt gataacatgc catggatggg ttgaatataa cttaaaaaag
    13261 aaattcttga cttattttga tttttggaca tattctatgg gagatgcttt tatttgtgta
    13321 tctgaaacta tgaaaaaaag attggagagt ataataaaaa aataagaaga tagttgcaat
    13381 aaataacgga attaatgtat caaatagcga tttaaatgta gtaggtgttc aagactttaa
    13441 aaaagaattt tgtattccaa ataacaaaaa aatcatttgt tatgttggaa ggttggatcc
    13501 agaaaaaagg ccggatagat tccttgaatt tgcagaaaaa ttatttttag tcagagaaga
    13561 tgtgattttt attatggctg gaaatggtag tatgtgggct gctttgaaag aaaaaatttg
    13621 ccatttgaaa tgtagagata atttcaggtt acttggtgaa atctatccag ctactatagt
    13681 ttaccaaata tcggatttat tgtatattcc ttctgataca gaaggaatac ctatgtgtgt
    13741 tttagagtca atgtcacaag gaactccggt tttagctagt aatattggcg ggttaagtga
    13801 aattattgaa catagggttg atggattttt atttgagaag gaagatgttg agggagtgtg
    13861 tgcttgtgct aattttttac tcaatgattc tgagtatttg aaatatatag gtgagaatag
    13921 taaatcaaaa ataagaaaac atttttctgt gcaaaaaatg tttgtagaaa ccatgagagt
    13981 atatgatgaa ttattagaga agagtagtca tggataggaa tatagatcaa gaattagtaa
    14041 gtattataat accaacacat aataggtatg aatctctgat tagagctgtg aaaagttgtt
    14101 tacatcaaag ttataaaaat atcgaagtta taattattga tgataattat agtaatgtaa
    14161 atttaagaaa taaaattatc catcaatttg gctataccaa tcatagaatt aagttaattt
    14221 taagtaatga agatttaggt gcaactaatg ccagaaacat aggtatcaaa aattctagag
    14281 gtaagtatat atcattttta gacgatgatg atgaatatat gccagatcga attttaaagt
    14341 tgatggcttg ttttaaaaag agtagaatga agaatttagc tttagtttat agttatggaa
    14401 taataattta tccaaatggt acacgagaag aggagaagac cgattttgtt ggaaatccct
    14461 tgtttgttca aatggttcac aatatagcag gtacgtcatt ttggttgtgt aaaaaagagg
    14521 tgctagaatt aattaatggt tttgagaaaa tagattcaca tcaggacggt gttgttttat
    14581 taaaactact tgctcaagga taccaaattg atatagtgcg agaattcttg gtgaattact
    14641 acgctcacag taaagaaaac ggtatcactg gagtgacaca aaaaacaatt aatgcagatg
    14701 aagaatatta taattactgt aggaaatatt ttaatttatt gagtttcaac gagagaatat
    14761 tggttacaaa gaaatattat tctttaaaca taaagcggtt actattaata ggagacaaat
    14821 gcaaggcttt aaaagtaatc aagaaggcaa gagaagaaaa aatttttaac gaatttcctt
    14881 ttttggaata tatgttatta tatcattttg gttttttcta ttgtatatat gacaactatg
    14941 ttcaattaaa atttagaaag tgagaaacta ttgtgtatac tattataaaa tcaaatataa
    15001 aaaaatttag tttattaacg atatttattg ttgctggtca attattgcta atttatgcag
    15061 caactattaa tgctctggtg ttgaatgaat taattgcgat gaatttagag cggtttttga
    15121 aattgtcaat ctaccaaatg attgtctggt gtgggataat attccttgac tgggtagtga
    15181 aaaattatca ggttgaagtg atccaagagt ttaatctaga gattcgaaat agagttgcca
    15241 cagacatctc taactctacc tatcaagaat ttcatagtaa atcatcagga acatatcttt
    15301 cgtggctaaa taatgatgtt cagactttaa atgatcaggc ttttaaacaa ctttttttag
    15361 taataaaagg aatttctggt actatatttg cagttgtgac tcttaatcac tatcattggt
    15421 cattgactgt agccaccttg ttttcattaa tgattatgct acttgtacca aaaatctttg
    15481 catcgaaaat gcgagaagtt agtctaaatt taactaacca aaatgaagct tttttaaaat
    15541 ctagtgagac tatattgaat ggatttgatg tgttagcgtc cttgaatctt ttatatgtat
    15601 tgcctaagaa aattaaagaa gcaggaattt tattaaagat ggttatacaa agaaagacaa
    15661 ctgtagaaac gttagcaggc gctattagct tctttctcaa tatttttttt cagatatctc
    15721 tcgttttttt aacaggctat cttgcaataa aaggaatagt gaaaattggt actattgaag
    15781 caataggagc actaacaggt gttattttta cagcgctagg tgaattagga ggtcaattat
    15841 cctctattat tggtacgaag cctatttttt taaaattgta ttcaattaat ccaattgagt
    15901 caaataaaat gaatgatatc gaaccaaatg aggtgaatag agattttccg ttatatgaag
    15961 caaaaaatat ttgctataag tatggagata aagaaatatt aaaaaactta aatttttgtt
    16021 ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg aagcgggaaa tctacattat
    16081 taaaattatt gaatggcttt ttgagagatt atagtggaga attgcgattc tgcggggatg
    16141 atataaaaaa aacctcctat ttaaatatgg tttcgaatgt tctatatgta gatcaaaaag
    16201 cttatttgtt tgaaggtacg attagagata atattttatt ggaagaaaat tatactgatg
    16261 aagaaatact acagtcttta gagcaagttg gtttgagtgt aaaagatttt cctaataaca
    16321 ttttagatta ttatgttggt gatgatggga gattactatc aggagggcag aaacaaaaaa
    16381 ttactttagc tagagggcta attagaaata agagaatagt attaattgac gagggaactt
    16441 ctgctatcga taggagaact tcgttagcga ttgaacgtaa gatattagat agagaggatt
    16501 tgactgtcat tattgttacc catgctccgc atccggaact taaacaatat tttactaaga
    16561 tatatcaatt tccaaaggat tttatttaag aatatagggg agggaaacat gagattctat
    16621 tgtgaagctt atgaggtaat tactgaagag aaaaaagtat cattttttat gtagatgaaa
    16681 aacccttaag gtatctgtta tttgactata tatttctact agttctagct aaaaaaaaat
    16741 atcccaatct tatgaactgc accccaaaag ttagatttat tctgtctaac ttttggggtg
    16801 cagttcattt tgcatagttt tggcattcat cctagatatc catataaaat gtctgagatt
    16861 gttgaaatgt ctaaaaaaat atcagatcta aacgataaaa aagaatttca caaaaagaac
    16921 tgtgagttga ggtttcaaga tagtgttctt gataacataa atagtgtccc gggtacaact
    16981 catttattta gttgtttaaa tattcaaaca ttagtaaaaa ttattttata tatttttcga
    17041 tacaacagtt gtatgaaaat atttaatttt agagataaag agcttatctt ttttaataag
    17101 attgtaaatg ggctgataca aaatattgag gagaatttag aggatgatat tgaaaggata
    17161 ttgaaatatt tatatatatg tttatttaac gaaatattca ttattaagaa taaggtgaat
    17221 ttttttgatg atgtggaatt taatcagaca cttagtgagt ttttagataa attgtagagg
    17281 gaatggttat gagtaacaat actaagtata tctttttatc tccacattta gatgacgcaa
    17341 ttttttcctg tagtgattat atttcaaaat taacttcaga aggagaaatt gtacttgtta
    17401 ttactatatt ttctggttac cctttgagcc aacagctaca gccctctgct aagcaatttc
    17461 ataagttgtg taaccttggg aaatatccga ttgaagaaag gaagaaagaa gacaggttag
    17521 cttgtgaacg tctacaatgt gattttagac acttatcgta ctatgaatgt ctctatagga
    17581 aagatagaaa tggcaatttt ctataccgtc atatctatag tgaattaaaa aatgaggaca
    17641 cattaaagaa tgatatcata aaagagctgt taatgcattt agacgataaa tgtgtcgtat
    17701 attgtccgct ttcacttggt gaccatgttg atcatgtttt tgtgaatagt attggaaggg
    17761 cgcttgaatt tatgcgttat aaagtaatat attatgagga cttcccatat gtaagtgata
    17821 gtagtatggt tagttatatg ggaaaaacta aagaattaaa aatgtatcaa gaggaacttg
    17881 atgaaaaaca ttatattgat agaatatcat caatattgtg ctataaatct cagattttga
    17941 taatctggaa atcagttgaa aaacttttaa acaatattaa agagttgtat ttaaggaatg
    18001 gggcagctta ttctattaga ttttggatta agaaataagg aagtagtttt atgaatatag
    18061 cagtaattgg tttggggcat gttgggctgg cctacgcgtt actatttgca tctaaatata
    18121 aagttgttgc atatgatata gattctgtaa aaataaataa tttaaaaaag ggcattcttc
    18181 catctaaaaa tgaagagctt atgaagtttt tttgcgagaa taacttaaat attacttttt
    18241 ttgatacatt ttctgaaatt aaaaataata ttgattatta tattattgcg cttccgacag
    18301 attatgatga gaaaattggt agttttaata catatgaaat cgaacaaacg gtatcgaaga
    18361 ttctgagggt aaaacctaat ggaaagatta ttttaaagtc aacagttccg ttcggctttt
    18421 caaacaaatt aaaaaggctg tttgatacaa aaaatatcat ttttgtccct gaatttttga
    18481 gagaaggttg ttctatatat gataatttat atccaagtcg catagttgtt ggagatgaga
    18541 cagttgaagg aagaaaaatt gcagagttgt tcctttcgat tagtactcat agtactgcca
    18601 atattaaaaa tgttatgtta gtttctccta ctgaagcaga agcaattaag cttttttcta
    18661 acacattctt agctctccgt gttgcttttt ttaatgaact agattctttt gctgagagga
    18721 gaagtttaaa tgctgaagtt gtaataaaag gtgtttgttt agatccaaga attggaaatt
    18781 tttataataa tctttctttt ggatttggag gatattgtct tcccaaagat actaaacaat
    18841 taaaaaaaga atttatagaa ataaatgccc cagtgataga agcgattgat atttcaaaca
    18901 caaatagaaa acagttcata gttaaacaaa tattggaacg aaagccaaag atagtaggaa
    18961 tatataaatt ggggatgaaa tataattcag ataattacaa agagtcagct attttaagta
    19021 taattaatga actattgatt gtcggtataa aaattttagt atatgaacca aatttaaacg
    19081 ttagtataga taacgtaatt tttgaaaaga attttgaact atttacaaaa caaagtgatc
    19141 taattgttgc aaatagatgg gataggggcc ttgaagctta taaagataaa gtttacacaa
    19201 gggggatctg gataagagat taactattga tattaaaaag gcaataattt ataaaatttg
    19261 tacaaaaaaa tgttaaattt tcacattttc atagtatact gtttaataga aagtaggttc
    19321 tttgtaaccg ctccattata aaatcctttc actcttccgg tatactatta ggaaaaacat
    19381 aactggagga tattttgagc tcacacctca tcgttccagt ggctgttccc caagctcgtg
    19441 tactgcccaa aaaagttaga cattctattt agaacgagga ttgagttctg tattgtacaa
    19501 ggctcggtcc ttttagagtc agcttaaggc tggctttttt attttttcta actatcagaa
    19561 tattttgaca aatgaacaca aataatgata taatatgcaa aagctaggag gtggtaggat
    19621 gattgaaaaa atggaattgg gggaatttta caaggaatta cgtttggcga gaaagctcaa
    19681 gcagtcagat gtggcttgtg acgggctaac agcttctcag ttgtccaagt ttgagctagg
    19741 gcagtccatg ttgtctgctg ataagctcat attagccatc caagggatca atgtgacctt
    19801 tgatgagttt gggcacaagc tcaacaacta tcaagaatct ccacatatgc agattggtag
    19861 aaaggttgtg gatcgctttg ctcatcaaga tatagctggc ttagagcaac tgttggagga
    19921 agtcgagcaa gaacagatgg cagagactta tcgtcgtttg aatgctattg taatcaaaga
    19981 tgccatccac tcactagata aaagctaccc actagcagag gaggatagcg agtttttgac
    20041 cacctatctc tatgctatcg agtcttggac ctggtttgaa ctctatctct tttgcaatac
    20101 tctgcccttc ttgagcaatc aagatctgat ctttttatca acctccttac tcgaaaaatc
    20161 caaagaattt aaagagttag tacacaatcg attgtatatg aagcaaggac tcttaaatat
    20221 catctcagag ctcatggagc gcaaactttt ttcttatatc ccaatctttg aagccgagct
    20281 ggagagtatg ctccgtccat acgatgtttt tgagaaagtg ttgtggcagt ttttaaagaa
    20341 gatgagcatt ttccttcaaa ctaagggaag caatcaaaaa gagattgaac actttatcca
    20401 atctctgcaa gtattagaaa atccacaatt aatagccctt tttgaattgc gtttgcagca
    20461 atacaaaaag cttatcgatt agttagaaat ggcaaaataa taataatctc agcaacgatt
    20521 ttcaataatg ttaaaatttg tttcttcata tttctccact cctcattagt agtaacttta
    20581 ttataccaga gaagtaatca aattcaccaa aatcgcaaat ctgaaatttc tataagaaaa
    20641 aatatcaaat atgcgatttt ctaaaataag ccaattttcg tgttatactg tacttgtaaa
    20701 gcacttgaag caaatcctag gtcacagaag tggtttacaa atgaagataa ttgaaggagt
    20761 gtaaaagatg ttaaatttac aatttgcaga aacaatggaa ttgacagaag ctgagttgga
    20821 gatagtttat ggaggggaat ttgggaataa tgctgttatc ccagccggtg cttggggagg
    20881 gttcgggaca ccttggtcaa tcactaattt ctggaagaaa aattttaacg atagacctga
    20941 ctttgattct gaccgccgtc gttattaata tccaaagccc ttgccttttc ttgggtaggg
    21001 gctgtcttta tttcatagta taggaggaaa tagaatgaaa aagataatct cacaccgcta
    21061 ctttattata gtttttctac tagttattgc tgaccagaag ttcagtgttc tagttttacg
    21121 cagcgacctt gttactgggc tatctgactt tgcctattat ctgtcggata tgatgttgaa
    21181 ttttcttgtg gttttatttg ctcttattgc tatgatttgg tcggggaaat ggcagaaaat
    21241 caatagtaga aagtttaaag gatcctatct tttctattcc ttcctagctc tgcttgcttt
    21301 tgttgtttgg aatttcgtta ccttttttct tttcccacct actcgaaatg aaatttctta
    21361 tcaacatgct gctccgactt ttacaggggc tacagcattt ttgatgtatt ttttctatcc
    21421 tgtgattgca ggtcccattt ttgaagagat aatccatcgg ggattggtga tgacagctct
    21481 ggaaaaagga aagaaatggg ggctagatgt acttggctct gctattttat ttggggtctc
    21541 gcacattagt aatcacggtt gggtcttgac agactttgtc ttctatatgg gtggaggtct
    21601 tatatttgca gtcttattta gaatgacaaa gtcaatttat tggcctattg gactgcatat
    21661 agtctacaat ggtattggtc agcttttgat gttactgtaa ttttggttgt tagtagtatc
    21721 gcggtctatt cttggggaaa gattcccatt tgaacttaag aaggagttgt aatgaaagta
    21781 tttcttcaaa atagagattt taggcaatta actatcaacc agtggatttc aacgcttggg
    21841 gatacgattt tttatctggc cttcctgaat tatgtggcag atgcgtcttt tgcccctttg
    21901 gcgattttac ttatcacgat ttcagaaacc cttccccaag ttctacaaat ctttctggga
    21961 gttttggcgg attttcaaca tcatcgtgtc ttgaaataca cagtcattag ttttacaaaa
    22021 tttttgcttt actctatagt gtccctatcg ctttcagggc agtctttttc cttgttgcta
    22081 gtaaccttta tttgtatgat taacctcttg tctgacacat tgagttattt ttcaggcgcc
    22141 atgctcactc cgattttcat tagaattatt gggcaagatc atctggcaga agctattgga
    22201 tttaaacagt caactgttag tttagtgaaa acaatcagta atatcctagg aggagtctta
    22261 ctaggtattc tatccatcca gtttatttcc ttactgaacg ctcttacctt tttaatcgca
    22321 tttttaggta tcctcttcat aaaaactgac ctcttgaaag tagaaaaaac gattagctat
    22381 caagaaggac tctctgtaaa atccttttgc cagcatttgc tccaatcatc gaaattgata
    22441 tggaatatga ataaggtgct cttggttttg tttattatct ctactagtca agcagtgata
    22501 aatgttacag ttcctgtctc tactctattt ttgaggaatc aacccttttt gaatttacaa
    22561 acaggtcaat ctcttgcctt gctatccact tttgaactgt cagccctgat tgtcggaagc
    22621 cttgtaagtg gctatctgca acataccatt tccataaaaa cagctctcta tgcctcactt
    22681 gtcatccagt tgcttcttct agtaggattt gccacagttc gttttgactg gattctcatc
    22741 tttagtacct tggatgcctt tttcgcaggt gttctctctc ctagattgca agaactcgtc
    22801 tttaaacaaa tacctgagga gtcaatggga gcagttcaat cttctatcag tgccattacg
    22861 gttgttttac ctagcttatt tacaatatct ttggtaacca ttgctactag ctttggaact
    22921 ctggcagtta gctttgtttt attgctattt cttctagttg cctttgttat gcttctgaat
    22981 attcgtgaaa gtatttagtg gagaatttct ataatatatg tttgagactg gattgccagt
    23041 ctttttatga tggtcaaaat caacagactt tttctctttt ctgaatgtgt tatagtagac
    23101 tgaatctaaa atagtacgaa acaattgcta aaacatttat agaaattaat tttactttcc
    23161 caatcgattt gttctcatct tatttcaatc tgctatacgc gtacgtaaat aatgaaaaga
    23221 attaaataat aggcttgtgc gataactatt tgaaacaaga ttagctggtt agaaaatcca
    23281 acaagatagt gaaggaatct aatataaaat atacataatt tagtttattt tatgttataa
    23341 aagttgtact aaaagactta cgattatctt gaatgcctta gggaaacatg ctatactact
    23401 tgtatgatta ttttacaagc taataaaatt gaacgttctt ttgcaggaga ggttcttttc
    23461 gataatatca acctgcaggt tgatgaacga gatcggattg cccttgttgg gaaaaatggt
    23521 gcaggtaagt ctactctttt gaagatttta gttggagaag aggagccaac tagtggagaa
    23581 atcaataaga aaaaagatat ttctctgtct tacctagctc aagatagccg ttttgagtct
    23641 gaaaatacca tctatgatga gatgcttcat gtctttgatg acttacgtcg gacagataaa
    23701 caactgcgtc agatggagct ggagatgggt gaaaagtctg gtgaggattt ggataaactg
    23761 atgtcagatt atgaccgctt atctgaaaat tttcgccaag caggtggctt tacctatgaa
    23821 gctgatattc gagcgatttt gaatggattc aagtttgacg agtctatgtg gcagatgaaa
    23881 attgctgagc tttctggtgg tcaaaatact cgtttggctc tagctaaaat gctccttgaa
    23941 aagcccaatc tcttggtctt ggacgagcca actaaccact tggatattga aaccatctcc
    24001 tggctagaga attacttggt aaactatagc ggtgccctca ttatcgtcag ccacgaccgt
    24061 tatttcttgg acaaggttgc gacaattacg ctagatttga ccaagtattc cttggatcgc
    24121 tatgtgggga attactctcg ttttgttgag ttgaaggagc aaaagctagc tactgaggca
    24181 aaaaactatg aaaagcaaca gaaggaaatc gctgctctgg aagactttgt caatcgcaat
    24241 ctagttcgtg cttcaacgac caaacgtgct caatctcgcc gtaaacaact agaaaaaatg
    24301 gagcgtttgg acaagcctga agctggcaag aaagcagcca acatgacctt ccagtctgaa
    24361 aaaacgtcgg gcaatgttgt tttgactgtt gaaaatactg ctattggtta tgacggggaa
    24421 gttttgtcac aacctatcaa cctagatctt cgtaagatga atgctgtcgc tatcgttggt
    24481 ccaaatggta tcggcaagtc aacctttatc aagtctattg tggaccagat tccttttatc
    24541 aaaggtgaaa agcgctttgg cgctaatgtt gaggttggtt actatgacca aacccaaagc
    24601 aagctgacac caagtaatac ggtgctggat gaactctgga atgatttcaa actgacacca
    24661 gaagttgaaa tccgcaaccg tcttggggcc ttccttttct caggagatga tgttaaaaaa
    24721 tcagtcggca tgctatctgg tggcgaaaaa gctcgtttgc ttttagctaa attgtctatg
    24781 gaaaacaata actttttgat tctggatgag ccgaccaacc acttggatat tgatagtaag
    24841 gaagtgctag aaaatgcctt gattgacttt gatggtacct tgctttttgt cagtcatgat
    24901 cgttacttta tcaatcgtgt ggcaactcat gttttggaat tgtctgagaa tggttcaact
    24961 ctctaccttg gagattacga ctactatgtt gagaagaaag caacagcaga aatgagtcag
    25021 actgaggaag cttcaactag caatcaagca aaggaagcaa gtccagtcaa tgactatcag
    25081 gcccagaaag aaagtcaaaa agaagttcgc aaactcatgc gacaaatcga aagtctagaa
    25141 gctgaaattg aagagctaga aagtcaaagc caagccattt ctgaacaaat gttggaaaca
    25201 aacgatgccg acaaactcat ggaattacag gctgagctgg acaaaatcag ccatcgtcag
    25261 gaagaagcta tgcttgagtg ggaagaatta tcagatcagg tgtaaagatg gaacatcttg
    25321 gaaaagtatt tcgtgaattt cgaacaagtg gaaattattc tttaaaggaa gcagcaggcg
    25381 aatcctgctc tacctctcag ttatctcgct ttgagcttgg ggagtctgac ctggcagtct
    25441 cccgtttctt tgagattttg gataacattc atgtaacaat cgaaaatttc atggataagg
    25501 caaggaattt tcataatcat gaacatgtgt ctatgatggc acagattatc ccactttact
    25561 attcaaacga tattgcaggt tttcaaaagc ttcaaagaga acaacttgaa aagtctaaga
    25621 gttcgacgac ttccctttat tttgagctga actggatttt gctacaaggt ctgatttgtc
    25681 aaagagatgc gagttatgat atgaagcagg atgatttgga taaggtagca gattatctct
    25741 tcaaaacaga agaatggacc atgtatgagt tgattctttt cggtaacctc tatagtttct
    25801 acgatgtaga ctatgtcact cggattggta gagaagttat ggagagggag gaattttacc
    25861 aagagattag tcgccataag agattagtgt tgattttggc cctcaattgt taccagcatt
    25921 gtttagagca ttcttctttt tataatgcca actattttga ggcttataca gagaagatta
    25981 ttgacaaagg tattaagctt tatgagcgta atgttttcca ttatttaaaa ggttttgcct
    26041 tatatcaaaa aggacagtgt aaagaaggct gtaagcagat gcaagaggcc atacatattt
    26101 ttgatgtgtt aggtcttcca gagcaagtag cctattatca ggaacactac gaaaaatttg
    26161 tcaaaagtta attttcccaa ataagggaaa aaataaaaag ctcctttcgg ttttgataca
    26221 atagtttcaa aatttgagag gagctttaat atgaatcgct atgcagtgca gttgattagc
    26281 cgtggggcta tcaataaaat gggaaatatg ctctatgatt atggaaatag tgtctgcttg
    26341 gcttctatgg ggactatagg acagacagtt ttaggaatgt atcagatttc tgagctcgtc
    26401 acatctattc tcgtcaatcc ctttggcgga gttatttcag accgtttttc tcgtcgtaag
    26461 attttaatga cggcagatct tgtttgtggg attctttgtc tggctatttc tttcataagg
    26521 aatgatagct ggatgattgg cgctttgatt gttgctaaca ttgtgcaggc tattgctttt
    26581 gccttttctc gcacagccaa taaagctatc ataactgaag tggtggagaa agatgagatt
    26641 gtgatctata attctcgcct agagctggtt ttgcaggttg taggtgttag ctctcctgtt
    26701 ctttccttcc ttgttttaca gtttgcaagt ctccatatga cgctactgct agactcgctg
    26761 acttttttca ttgcttttgt tctagtggct ttctttccaa aagaggaagc aaaagttcaa
    26821 gagaaaaagg cttttactgg gagagatatt tttgtagata tcaaggatgg gttacactat
    26881 atctggcatc agcaagaaat tttcttcctt ttgctggtag cttccagcgt taatttcttt
    26941 tttgcagctt ttgaatttct acttcccttt tcgaatcagc tttacgggtc agaaggagcc
    27001 tatgcaagta ttttaactat gggggctatt ggttccatca ttggggctct tctagctagt
    27061 aaaattaaag ctaatattta taatcttttg attttactgg ctttgacagg tgtcggagtt
    27121 tttatgatgg gattaccact tccaactttt ctttcccttt ctggaaattt agtttgtgaa
    27181 ttgtttatga cgatttttaa tattcacttt tttactcaag tacaaaccaa ggttgagagc
    27241 gaatttcttg ggagagtact gagtacaatt tttaccttag ctattctatt tatgcctatt
    27301 gcaaaaggat ttatgacagt cttgccaagt gtacatctct cttctttcct gataattgga
    27361 agtggtgtta tcatcttgtc ttgtatatcg tttatttatg ttcgaactca ttttgaaaaa
    27421 ttgatataag gttgcttgag tttcaaaaat aatttcaaac taagtgtttt ttccgccctt
    27481 ctcgtttgtg aggagggctt gttttatggt aaaatggtct tatgaataaa agaatgaatg
    27541 agttagtcgc tttgctcaat cgctatgcga ctgagtacta taccagcgat aatccctcgg
    27601 tttcagacag tgagtatgac cgcctttacc gtgagttggt cgagttagaa actgcttatc
    27661 cagagcaagt gctagcagac agtccgactc atcgtgttgg tggcaaggtt ttagatggtt
    27721 ttgaaaaata cagtcatcag tatcctcttt atagtttgca ggatgctttt tcacgtgagg
    27781 agctagatgc ttttgatgcg cgtgttcgta aggaagtggc tcatccgacc tatatttgtg
    27841 agctgaaaat cgatggctta tctatctcgc tgacttatga aaaggggatt ttggttgctg
    27901 gggtaacacg tggagatggt tcaattggtg aaaatatcac agaaaacctc aagcgtgtta
    27961 aggacatccc tttgactttg ccagaagaac tagatatcac agttcgtggg gaatgttaca
    28021 tgccacgcgc ttcctttgac caagttaacc aagtgcgcca agaaaatgga gagcctgaat
    28081 ttgctaatcc tcgtaatgcg gcagcaggaa ctctgcgtca gttggataca gcagtagttg
    28141 ccaagcgtag tcttgcaacg tttctctatc aagaagccag cccttcaact cgtgatagcc
    28201 aagaaaaggg tttgaagtac ctagaacaac taggttttgt ggtcaatcct aagcgaatct
    28261 tggctgaaaa catagatgaa atctggaatt ttatccaaga agtaggacag gaacgggaaa
    28321 atctgcctta cgatattgat ggagtggtaa tcaaggtcaa cgacctagca agtcaagaag
    28381 aacttggttt tacagttaag gctccaaagt gggcagtagc ctacaagttc cctgccgaag
    28441 aaaaagaagc tcaactctta tcagttgact ggacagttgg ccgtaccggt gttgtaactc
    28501 caactgctaa tctaacacca gtacaacttg ccggtacgac tgttagccgt gcgaccctgc
    28561 acaatgtaga ttatattgct gaaaaagata tccgaaaaga cgatacggtc attgtatata
    28621 aggctggtga catcatccct gccgttttac gtgtggtaga gtccaaacgg gtttctgaag
    28681 aaaaactaga tatccctaca aactgtccaa gttgtaactc tgacttgttg cactttgaag
    28741 atgaagtggc cctacgttgt atcaatccgc gttgccctgc tcaaatcatg gaaggcttga
    28801 ttcactttgc ttctcgtgat gctatgaata ttacaggcct tggtccatct attgttgaga
    28861 agctttttgc tgctaattta gtcaaggatg tggcggatat ttatcgtttg caagaagagg
    28921 atttcctcct tttagagggg gttaaggaaa agtccgctgc taaactgtat caggctatcc
    28981 aagcatcaaa ggaaaattct gccgagaagc tcttatttgg tttgggaatt cgtcatgtcg
    29041 gaagcaaggc tagtcagctt ttacttcaat atttccattc aattgaaaat ctgtctcagg
    29101 cagattcaga ggaagtggct agtattgaaa gtctaggtgg cgtgattgcc aaaagtcttc
    29161 agacttattt tgcgacagaa ggctctgaaa ttctgctcag agaattgaaa gaaactgggg
    29221 tcaatctgga ctataaagga cagacggtag tagcggatgc ggccttgtca ggtttgaccg
    29281 tggtattgac aggaaaattg gaacgactca agcgctcaga agctaaaagt aaactcgaaa
    29341 gtctgggtgc caaagtgaca ggtagtgttt ctaaaaagac cgacctcgtc gtggtaggtg
    29401 cagacgctgg aagtaaactg caaaaagcac aagaacttgg tatccaggtc agagatgagg
    29461 catggctaga aagtttgtaa tggatcgttt aaaaacagag tttagagaat atgactatgt
    29521 ctgttaattg agacgagatt gacaaaaatt tattagtgaa atagaaacaa agtaaaaagg
    29581 aaaaataaaa aatgtataac taccctatgc gcattcatta ccatcgtaag aatggagaat
    29641 atgacacttg ctcctttgta aaaagtcagg atcaacgaat tgatttgcta acctacaaag
    29701 aagattattt tggagcttta tttagctttg aacacccaag ttcacatgtt atagaaagct
    29761 tgaattttgt ggttcataca ggtcaaacta gtaaagaata ttctatccgt tttaatcact
    29821 atcccctatt aacagaggtc tggattttgg aaggcgatga taggatttat tactctgaaa
    29881 atcctgctat tgccagtcct ttctataaaa atcaaaatcc ttttgccttt gataaggcca
    29941 ttaacagtgc tagttttgac catcattggg gttaccaagg agaattgggt tgccgtgtag
    30001 aggacaatca ggctcatttt tccctctggt cacctacagc gacagaagtg caagttgtcg
    30061 tttatgaatc agctgctaat gatgcacccg tttggaagac ttttgagatg aaaagaggca
    30121 atagctactc ttataatcat aaggacaata caatcggtgt ctggagtttg gatgttgagg
    30181 aagatttggt aggtaaggct tatcagtatc aagtccaatt ccctcatcac caaacactga
    30241 cacgtgatcc ttatacaatc gcgaccagcc ctgatggcaa acgttcagct attctgagcc
    30301 atgtagaaaa gcaagttgaa aacttcgagg ttaagcacgg ttcggaggct acttggcgct
    30361 tggaaaatcc atgtaaggca gttatctgtg aaatgcatat tcgtgatttg actaaatcac
    30421 ctacatcggg tgtagatgaa catcttcgag gaactttctt gggtgctgct caggctggaa
    30481 cagttaacca atacggccag tcaactgctt ttgattacat caagaagctg ggctacaatt
    30541 atgttcaatt gcaaccaatt gcagaccgtc ataaagaata cgatgaggat ggaaatgtaa
    30601 cctacaactg gggttatgat ccacaaaact ataacgcgcc agaaactagt ttttcaacta
    30661 atccagatga tccagctcag gtcattcgtg atttgaaggt gatggttcaa gcttatcacg
    30721 atgcgggtat tggagtcatt atggatgtag tctataacca taccttctca gttgttgatg
    30781 caccattcca aacaacagtc cctgattact attatcgtat gaatccagat ggtaccttcc
    30841 agaatggaac gggtgttgga aatgaaacag ccagtgaaca cgaaatgttt cgcaagtata
    30901 tgattgattc tcttctatac tgggtgcagg aatataatat tgacggcttc cgttttgact
    30961 tgatggggat tcatgatgtc aagaccatgc agatgattcg tcaaagcttg gatgaaatcg
    31021 actccaacat tatcctctat ggagaaggat gggatatggg aacaggtctt gccccttatg
    31081 ataaggccaa gaaggacaat gcctaccaga tgccaaatat tggtttcttt aatgacaatc
    31141 agcgcgatgc tgtcaaaggg ggagaagttt atggtgctat caagtcaggt tttgtcagtg
    31201 gtgctgcgac agagccaatt ctagctaaag caatcctagg aagtcgtgaa ttaggaagct
    31261 atacacatcc aaatcaggtg cttaactatg tagaagccca tgacaattac aatcttcacg
    31321 atttattggc aacccttcat ccagaccaaa gttcagagca aatcatgcgc aaggtcgaaa
    31381 ctgccacagc catgaatctg ctcatgcagg ggatggcctt tatggaaatc ggtcaagaat
    31441 ttggtcgtac caaactggtt gcgactggtg aaaatggtga gttgacccat gatgatagag
    31501 agcgtgcgat gaatagctat aatgctcctg acagtgtgaa ccaagtgaac tggaacttga
    31561 ttaatgagcg tcaagacagt attgagttta tccgtcaagt catccgattg aagacaaaaa
    31621 ctggtgcctt ttcttactct agctatgatg aaatttacca tcatgtcttt gtgcattctg
    31681 cgattgaaca tagcggctgc cttatctatg aagttcacgg caaagaacac ctcttggtag
    31741 ttgtgaatgc taaatcagaa ccctatcaat ttgaaaatgc aggaaattta gctatgttgg
    31801 taaccaacag tcgctcaaaa gaagataatg ttttaaatga tattagtcta gctgtcttga
    31861 gtgttttata aataccatct atctcgctat ttttagacag aaaaattccc agttatgagt
    31921 attggtaaaa aatccattca ttgaaattga aagaatagaa agaacctggc taacagctca
    31981 cttgtataga aaatttgata aatattttca cgaaacaaga cctcctatca aagtttttga
    32041 acatttgata ggaggtcttt ttattatgaa gacttttacc tagactttgt ttcagcaatc
    32101 tatgacagtt atagtaggct gaaattggaa tagcacaccc ttgtttctga aacattgtga
    32161 gaaattggtt tggctgtccc caaccaaatt gttcagtttt tttattttac tatagatgat
    32221 actcattcac gctcttcgaa aatttcttca accacattag cctcgccttg acgtagtgga
    32281 tttttttaat ttttattgag tatactttga aaaatcaaga ttgtgaaaat aatctcaaaa
    32341 attttgcaaa aagggttgtg attttctgaa aatttggtaa aatatatctt aatcattttc
    32401 aggaggacaa gaatttgaca agatatcaaa atttagtaaa tggaaaatgg aaatcatctg
    32461 aacaagaaat tacgatttat tcaccaatca atcaagaaga attgggtaca gttccagcca
    32521 tgactcagac tgaagctgat gaggctatgc aagctgcgcg tgcagccctg ccagcatggc
    32581 gagctttatc agcaattgaa cgtgcggctt atttgcataa aacagcagct attttagaac
    32641 gcgataagga aaaaattggt actatccttg ccaaagaagt agcaaaaggg attaaagcag
    32701 caattggaga agtagtgcgt acagcagact tgattcgtta tgctgctgag gaaggtctcc
    32761 gtatcactgg acaagcaatg gaaggtggtg gttttgaggc agcaagtaaa aacaaactgg
    32821 ctgttgtccg tcgtgaacca gttggtatcg tgctagcgat tgctcctttt aattatccag
    32881 ttaatttatc tgcttctaaa attgcacctg ccttgattgc agggaatgtg gtcatgttta
    32941 agccaccaac acaaggttcc atttctggac tcttgttggc taaagcattt gaagaagcag
    33001 ggattccggc aggtgttttc aacaccatta caggtcgtgg ttcagaaatt ggggattata
    33061 tcattgagca caaagaagtc aacttcatca actttacagg ttcaactcct attggagaac
    33121 gtattggtcg tttagctggt atgcgtccta tcatgttgga acttggtggg aaagatgcag
    33181 ctcttgtact agaagatgca gatttggaac atgctgccaa gcaaattgtt gcgggagcct
    33241 ttagctactc aggacaacgt tgcacggcca ttaaacgtgt cattgttctc gaaagtgtag
    33301 cagataaatt agctactttg cttcaggaag aagtttctaa attaacagtt ggtgatccat
    33361 ttgacaatgc tgatattaca cctgttattg acaatgcttc agccgacttc atttggggct
    33421 tgattgagga tgcacaagaa aaagaggctc aggctcttac accaatcaaa cgtgagggca
    33481 atctcctctg gccagtgctt tttgaccaag ttacaaaaga tatgaaagtg gcatgggaag
    33541 agccatttgg tcctgtttta ccaatcattc gtgtggctag tgtagaggaa gctattgcct
    33601 ttgccaacga atctgaattc ggccttcaat catcagtctt tacaaatgat ttcaaaaaag
    33661 cctttgaaat tgctgaaaaa cttgaagtag gtacagtcca cattaataat aaaacccagc
    33721 gtggtccaga taatttccca ttccttggtg tcaaaggttc tggagctgga gtgcaaggaa
    33781 ttaaatatag cattgaagcg atgacaaatg tcaaatccat tgtttttgat gtgaaataac
    33841 gtgtaaaacc aggaaattgt tttcctggtt ttattttttt gctataaaat aataataatt
    33901 atagaaaaaa tacgaacttt ttggtattac aatagattga aaccagaata gtacacctct
    33961 acttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc
//
LOCUS       DBEROT010000023        33566 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.23, whole genome shotgun sequence.
ACCESSION   DBEROT010000023 DBEROT010000000
VERSION     DBEROT010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33566
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.23"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..450
                     /locus_tag="ACL8CG_001228"
     CDS             <1..450
                     /locus_tag="ACL8CG_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343823.1"
                     /translation="LIIYLFLLYLFIDLLMKSGILDEQIDKLSELSNLFTIKIETILT
                     VISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITLSFSILLCYLFNPSD
                     IKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSIINSF"
     gene            830..2983
                     /gene="comA"
                     /locus_tag="ACL8CG_001229"
     CDS             830..2983
                     /gene="comA"
                     /locus_tag="ACL8CG_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGS1343824.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2996..4345
                     /gene="comB"
                     /locus_tag="ACL8CG_001230"
     CDS             2996..4345
                     /gene="comB"
                     /locus_tag="ACL8CG_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGS1343825.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATIEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4515..5222
                     /gene="purC"
                     /locus_tag="ACL8CG_001231"
     CDS             4515..5222
                     /gene="purC"
                     /locus_tag="ACL8CG_001231"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS1343826.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5224..5367
                     /locus_tag="ACL8CG_001232"
     CDS             5224..5367
                     /locus_tag="ACL8CG_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS1343827.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            5424..9149
                     /locus_tag="ACL8CG_001233"
     CDS             5424..9149
                     /locus_tag="ACL8CG_001233"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGS1343828.1"
                     /translation="MDKRIFVEKKADFQVKSESLVREFQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9242..10684
                     /gene="purF"
                     /locus_tag="ACL8CG_001234"
     CDS             9242..10684
                     /gene="purF"
                     /locus_tag="ACL8CG_001234"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGS1343829.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10721..11743
                     /gene="purM"
                     /locus_tag="ACL8CG_001235"
     CDS             10721..11743
                     /gene="purM"
                     /locus_tag="ACL8CG_001235"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGS1343830.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11740..12285
                     /gene="purN"
                     /locus_tag="ACL8CG_001236"
     CDS             11740..12285
                     /gene="purN"
                     /locus_tag="ACL8CG_001236"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGS1343831.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12369..12878
                     /locus_tag="ACL8CG_001237"
     CDS             12369..12878
                     /locus_tag="ACL8CG_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS1343832.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12903..14450
                     /gene="purH"
                     /locus_tag="ACL8CG_001238"
     CDS             12903..14450
                     /gene="purH"
                     /locus_tag="ACL8CG_001238"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGS1343833.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFSDNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            14572..15834
                     /gene="purD"
                     /locus_tag="ACL8CG_001239"
     CDS             14572..15834
                     /gene="purD"
                     /locus_tag="ACL8CG_001239"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGS1343834.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVIYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16091..16207
                     /locus_tag="ACL8CG_001240"
     CDS             16091..16207
                     /locus_tag="ACL8CG_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS1343835.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            16237..16725
                     /gene="purE"
                     /locus_tag="ACL8CG_001241"
     CDS             16237..16725
                     /gene="purE"
                     /locus_tag="ACL8CG_001241"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGS1343836.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPIIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAAIFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16712..17803
                     /gene="purK"
                     /locus_tag="ACL8CG_001242"
     CDS             16712..17803
                     /gene="purK"
                     /locus_tag="ACL8CG_001242"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGS1343837.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVDELGEGIDF"
     gene            17813..18040
                     /locus_tag="ACL8CG_001243"
     CDS             17813..18040
                     /locus_tag="ACL8CG_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS1343838.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            18103..19401
                     /gene="purB"
                     /locus_tag="ACL8CG_001244"
     CDS             18103..19401
                     /gene="purB"
                     /locus_tag="ACL8CG_001244"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGS1343839.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19456..23394)
                     /gene="strH"
                     /locus_tag="ACL8CG_001245"
     CDS             complement(19456..23394)
                     /gene="strH"
                     /locus_tag="ACL8CG_001245"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGS1343840.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWTDTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASDLGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVLGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23709..24425)
                     /locus_tag="ACL8CG_001246"
     CDS             complement(23709..24425)
                     /locus_tag="ACL8CG_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1343841.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24773..26560
                     /locus_tag="ACL8CG_001247"
     CDS             24773..26560
                     /locus_tag="ACL8CG_001247"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGS1343842.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26557..27033
                     /locus_tag="ACL8CG_001248"
     CDS             26557..27033
                     /locus_tag="ACL8CG_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1343843.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27061..27966
                     /locus_tag="ACL8CG_001249"
     CDS             27061..27966
                     /locus_tag="ACL8CG_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1343844.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27953..28768
                     /locus_tag="ACL8CG_001250"
     CDS             27953..28768
                     /locus_tag="ACL8CG_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1343845.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28775..29179
                     /locus_tag="ACL8CG_001251"
     CDS             28775..29179
                     /locus_tag="ACL8CG_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1343846.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29432..30598
                     /locus_tag="ACL8CG_001252"
     CDS             29432..30598
                     /locus_tag="ACL8CG_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGS1343847.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30714..31751
                     /locus_tag="ACL8CG_001253"
     CDS             30714..31751
                     /locus_tag="ACL8CG_001253"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGS1343848.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31959..32813
                     /locus_tag="ACL8CG_001254"
     CDS             31959..32813
                     /locus_tag="ACL8CG_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1343849.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            32963..33220
                     /locus_tag="ACL8CG_001255"
     CDS             32963..33220
                     /locus_tag="ACL8CG_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="HGS1343850.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDCDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33262..>33566)
                     /locus_tag="ACL8CG_001256"
     CDS             complement(33262..>33566)
                     /locus_tag="ACL8CG_001256"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343851.1"
                     /translation="VVDGTDEVSSKHCFEVVDRTDEVSNHIYGKVKLTWFEEIFEEYK
                     SLHNKTHITKVLMNCTPKVRQKKSNFLGSIHSTPDTMRFFNFKDFLQLLLTHIKLF"
BASE COUNT         9279 a         6530 c         7821 g         9936 t
ORIGIN      
        1 ctgattattt atctttttct tttatatttg tttattgatt tactgatgaa gtcgggaatt
       61 ttagatgaac aaattgataa attatctgaa ctatctaatc tttttacaat taaaatagaa
      121 acaatattga cagtgatttc tgttgttttc acatttatag caactcttat tgaatatgga
      181 ttttctctct ttctgattac attatttttt gataagaata agaggaactt tggagatatt
      241 cttttatcta aaaatataac cttaagtttt agcattttac tttgttattt atttaatcca
      301 tcggatataa agtttgccta tttcagcgta ttgacagtat tactaattgg gataacaaat
      361 tatgcgagat ttaaaaattt aagattgaca gtagtgtttt ctgtaccatt tttatttaat
      421 gctataatgt ctattataaa tagtttttag aaatactaaa atttttttct ttacttaata
      481 atgatatgaa atcatttcgg ttttgttaac ttgtaattct tatattttct aggtagaacg
      541 tttgttctgc ctattttttt atccaaaaag tgcagttggg agggagatag gctcatttgg
      601 gaaggaagtc cagtttttgt ttagtgattg gggtaagata gttgttatca gatgagttta
      661 tactcttcga aaatcaaatt caaaccacgt caacgtcgcc ttgccgtata tatgtgactg
      721 acttcgtcag tcctatctac aacctcaaaa cagtgttttg agcagcctgc ggctagtttc
      781 ctagtttgct ctttgatttt cattgagtat tagggaaaag gagatgaata tgaaatttgg
      841 gaaacgtcac tatcgtccgc aagtggatca gatggactgc ggtgtagctt cattagccat
      901 ggtttttggc tactatggta gttattattt tttggctcac ttgcgagaat tggctaagac
      961 gaccatggat gggacgacgg ctttgggctt ggtcaaggtg gcagaggaga ttggttttga
     1021 gacgcgagcc attaaggcgg atatgacgct ttttgacttg ccggatttga cttttccttt
     1081 tgttgcccat gtgcttaagg aagggaaatt gctccactac tatgtggtga ctgggcagga
     1141 taaggatagc attcatattg ccgatccaga tcccggggtg aagttgacta aactgccacg
     1201 tgagcgtttt gaggaagaat ggacaggagt gactcttttt atggcaccta gtccagacta
     1261 taagccttat aaggaacaaa aaaatggtct gctctctttt atccctatat tagtgaagca
     1321 gcgtggcttg attgccaata tcgttttggc aacactcttg gtaaccggga ttaacattgt
     1381 gggttcttat tatctgcagt ctatcattga tacctatgtg ccagatcaga tgcgttcgac
     1441 actagggatt atttctattg ggctagtcat cgtctacatc ctccagcaaa tcttgtctta
     1501 cgctcaggag tatctcttgc ttgttttggg gcaacgcttg tcgattgacg tgattttgtc
     1561 ctatatcaag catgtttttc acctccctat gtccttcttt gcgacacgca ggacagggga
     1621 gatcgtgtct cgttttacag atgctaacag tatcatcgat gcgctggctt cgaccatcct
     1681 ttcgattttc ctagatgtgt caacggttgt cattatttcc cttgttctat tttcacaaaa
     1741 taccaatctc tttttcatga ctttattggc gcttcctatc tacacagtga ttatctttgc
     1801 ctttatgaag ccgtttgaaa agatgaatcg ggataccatg gaagccaatg cggttctgtc
     1861 ttcttctatc attgaggaca tcaacggtat tgagactatc aagtccttga ccagtgaaag
     1921 tcagcgttac caaaaaattg acaaggaatt tgtggattat ctgaagaaat cctttaccta
     1981 tagtcgagca gagagtcagc aaaaggctct gaaaaaggtt gcccatctct tgcttaatgt
     2041 cggcattctc tggatggggg ctgttctggt catggatggc aagatgagtt tggggcagtt
     2101 gattacctat aataccttgc tggtttactt taccaatcct ttggaaaata tcatcaatct
     2161 gcaaaccaag cttcagacag cgcaggttgc caataaccgt ctaaatgaag tgtatctagt
     2221 agcttctgag tttgaggaga agaaaacagt tgaggatttg agcttgatga agggagatat
     2281 gaccttcaag caggttcatt acaagtatgg ctatggtcga gacgtcttgt cggatatcaa
     2341 tttaaccgtt ccccaagggt ctaaggtggc ttttgtgggg atttcagggt caggtaagac
     2401 gactttggcc aagatgatgg ttaattttta cgacccaagt caaggggaga ttagtctggg
     2461 tggtgtcaat ctcaatcaga ttgataaaaa agccctgcgc cagtacatca actatctgcc
     2521 tcaacagccc tatgtcttta acggaacgat tttggagaat cttcttttgg gagccaagga
     2581 ggggacgaca caggaagata tcttacgggc ggtcgaattg gcagagattc gagaggatat
     2641 cgagcgcatg ccactgaatt atcagacaga attgacttcg gatggggcag ggatttcagg
     2701 tggtcaacgt cagagaatcg ctttggcgcg tgctctcttg acagatgcgc cggtcttgat
     2761 tttggatgag gcgactagca gtttggatat tttgacagag aagcggattg tcgataatct
     2821 catggctttg gacaagacct tgattttcat tgctcaccgc ttgactattg ctgagcggac
     2881 agagaaggtg gttgtcttgg atcagggcaa gattgtcgaa gaaggaaagc atgctgattt
     2941 gcttgcacag ggaggctttt acgcccattt ggtcaatagc tagaaagagg agaggatgaa
     3001 accagaattt ttagaaagtg cggagtttta taatcgtcgt taccataatt tttccagtag
     3061 tgtgattgta cccatggccc ttctgctcgt gtttttactt ggctttgcaa ctgttgcaga
     3121 gaaggagatg agtttgtcca ctagagctac tatcgaaccc agtcgtatcc ttgcaaatat
     3181 ccagtcaact agcaacaatc gtattcttgt caatcatttg gaagaaaata agctggttaa
     3241 gaagggggat cttttggttc aataccaaga aggggcagag ggtgtccaag cggagtccta
     3301 tgccagtcag ttggacatgc taaaggatca aaaaaagcaa ttagagtatc tgcaaaagag
     3361 cctgcaagaa ggggagaacc actttccaga ggaggataag tttggctacc aagccacctt
     3421 tcgcgactac atcagtcaag caggcagtct tagggctagt acatcgcaac aaaatgagac
     3481 catcgcgtcc cagaatgcag cagctagcca aacccaagcc gaaatcggca acctcatcag
     3541 tcaaacagag gctaaaattc gcgattacca gacagctaag tcagctatgg aaacaggtgc
     3601 ttccttggcc agtcagaatc tagcctactc tctttaccag tcctacaagt ctcagggcga
     3661 ggaaaatccc caaactaagg ttcaggcagt tgcacaggtt gaagcacaga tttctcagtt
     3721 agaatctagt cttgctactt accgtgtcca gtatgcaggt tcaggtaccc agcaagccta
     3781 tgcgtcaggg ttaagcagtc aattggaatc ccttaaatcc caacatttgg caaaggttgg
     3841 tcaggaattg acccttctag cccagaaaat cttggaggca gagtcaggta agaaggtaca
     3901 gggaaatctt ttagacaagg ggaaaattac ggcgagtgag gatggggtgc ttcatcttaa
     3961 tcctgagacc agtgattcta gcatggttgc agaaggtgcc ctactagccc aactttatcc
     4021 atctttggaa agagaaggga aagccaaact cacagcctat ctaagttcaa aagatgtagc
     4081 aagaatcaag gtcggtgatt ctgttcgcta tactacgact catgatgccg ggaatcaact
     4141 tttcctagat tcaactatta caagtattga tgcgacagct actaagactg agaaagggaa
     4201 tttctttaaa atagaggcgg agactaatct aacttcggag caggctgaaa aacttaggta
     4261 cggggtggaa ggccgcttgc agatgattac gggcaagaaa agttatctac gttattattt
     4321 ggatcaattt ttgaacaaag agtaatgttc gtgtttttag agttaaataa tttttaaact
     4381 gtgagaaaga ttcttcttgc agttttttct ttacaatttt tgaaaaacat ctactattta
     4441 ttcggttaaa ttcttgtgtt ttttggtttt ttgtggtaaa atgtgctcaa gtaatacgaa
     4501 aggcgaactt taaaatgtca aaacaattga tctattcggg aaaagctaaa gatatctata
     4561 caactgagga tgaaaatctt attatttcaa cttacaagga ccaggcgact gctttcaacg
     4621 gtgtcaagaa ggagcagatt gcaggtaagg gagtcttgaa taatcagatc tcatctttta
     4681 tttttgagaa attaaatgcg gctggtgtgg cgactcactt tgtggagaaa ctttcagaca
     4741 cggaacaact caataaaaag gttaagatta ttcctttgga agtcgtgctc cgcaactata
     4801 ctgctggttc tttttcaaaa cgttttggtg tggatgaggg aatcgccttg gagactccga
     4861 ttgtcgaatt ttactacaaa aatgatgatt tggatgatcc atttatcaat gatgagcatg
     4921 tgaaattcct acagattgcg ggtgaccagc agattgccta cttgaaggaa gaaacgcgtc
     4981 gtatcaatga actattgaaa gtctggtttg ctgagattgg gcttaaattg attgacttta
     5041 agctagagtt cggttttgac aaggatggca agattatctt ggcagacgaa ttttcaccag
     5101 ataactgccg cttgtgggac gctgatggca accacatgga taaggatgtt ttccgtagag
     5161 gattgggaga actaaccgac gtttatgaga ttgtttggga aaagttgcag gaattgaaat
     5221 aatctgtttg caacggaaaa ccttcgtctc tcaactaaaa ggactcaggc tgaaaaggtc
     5281 ccccagacct tttcactctg tagagaacta ggtgaactaa cagatgttta cgaaattgtc
     5341 tgggaaaagt tgcagggttt aaaataacaa cctcaaggct gtttgggaat attgcaagag
     5401 ctgaaataaa ggaataagaa ttgatggata aacgtatttt tgttgaaaaa aaggctgatt
     5461 ttcaggtcaa gtcagagagt ttggttagag agttccagca caacttggga ctgtcaagct
     5521 tgaaaagtat tcgtattgtg caagtatatg atgtatttga cttggctgag gacttgtttg
     5581 cacctgcaga gaagcacatt ttctctgagc agggaaccga ccatgtttta gatgaagtat
     5641 ctgtgcaggc ggatcttgct aactatgctt tctttgccat tgaaagtctg ccagggcagt
     5701 ttgaccagcg tgcagcttcg tcacaggaag ccttgctttt gttgggaagt tcgagtgacg
     5761 tgacagtcaa cacagcccaa ctttacttgg tgaataaaga tattgatgcg actgagttgg
     5821 aagctgtcaa aaactacctg ctcaatccag ttgattctcg tttcaaggat atcacgacag
     5881 ggattgccaa gcaggagttt tcagagtcag acaagaccat tccaaaattg actttctttg
     5941 aaagctatac agcagaagac tttgctcgct acaaggccga gcaagggatg gccatggaag
     6001 tggatgattt gctctttatc caagactact ttaagtcaat cgggcgcgtg ccaactgaga
     6061 ctgaactcaa ggttttggac acttactggt ctgaccactg ccgtcatacg acttttgaga
     6121 cagagttgaa acacatcgac ttttcagctt ctaaatttca aaagcaattg cagtcaacct
     6181 atgacaagta tattgccatg cgcgaggagt taggtcggtc tgaaaaacca caaaccttga
     6241 tggatatggc gactattttc ggtcgttatg agcgtgctaa cggacgattg gatgatatgg
     6301 aagtctctga cgaaatcaat gcctgctcag ttgaaattga agtggatgtt gatggtgtca
     6361 aggaaccttg gctcctcatg tttaaaaatg aaacccacaa ccatccaaca gaaattgagc
     6421 catttggtgg agcggctacc tgtatcggtg gagctattcg tgatccgttg tcaggccgtt
     6481 cctatgttta ccaagccatg cgtatttcag gtgctggtga tattacagca ccgatttcgg
     6541 aaactcgtgc tgggaaattg ccacaacaag tcatttctaa aacagcagct catggttatt
     6601 cttcatatgg taaccagatt gggcttgcca caacctacgt tcgtgaatac ttccacccag
     6661 gctttgtagc taaacgtatg gaacttggtg ccgttgttgg tgcggctccc aagggcaatg
     6721 ttgtccgtga aaaacctgaa gcaggtgatg tgatcatcct tctcggaggc aaaacaggtc
     6781 gtgatggtgt cggtggtgcg acgggctctt ctaaggttca aacagttgag tctgtagaga
     6841 ctgctggtgc tgaggttcaa aaaggaaatg ccatcgaaga acgcaagatt cagcgcctct
     6901 tccgtaatgg caatgtcact cgtctgatca agaagtccaa tgactttggg gcaggcggcg
     6961 tctgtgtggc tatcggtgaa ttggcagacg gtcttgaaat cgacctcaac aaggtgcctc
     7021 ttaaatacca gggcttgaat ggtacagaaa ttgccatctc tgaatcacaa gaacggatgg
     7081 cggtcgtggt tcgtcctgaa gatgtggata ccttcgttgc cgaatgtaac aaagaaaata
     7141 ttgatgctgt tgtggtggcg acagtaactg aaaaaccaaa tcttgtcatg cactggaatg
     7201 gtgagacaat cgttgacttg gagcgtcgtt tccttgacac caatggtgtg cgcgtggttg
     7261 tcgatgccaa agttgtggac aaggatgtca aactcccaga agagcgtcaa acatctgctg
     7321 aaacactgga atcagatacc cttacggttc tatctgacct caaccatgca agtcaaaaag
     7381 gattacagac tatctttgac tgctctgttg gacgctcaac ggttaatcac ccacttggtg
     7441 gtcgttacca actcacacca actgaggcat ctgtgcagaa attgccagtt caacacggtg
     7501 tgactcatac tgcgtcggtc attgctcaag gtttcaaccc atatgtagct gaatggtctc
     7561 cataccacgg tgctgcttat gcggttatcg aagcaactgc tcgtttggtg gctgctggtg
     7621 ccaactggtc taaggctcgt ttctcttacc aagaatattt cgagcggatg gacaagcaag
     7681 cagagcgttt cggtcagcca gtagctgctc ttctaggttc tattgaagca caaattcagc
     7741 ttggcttgcc atctatcggt ggtaaggact ccatgtctgg tacctttgaa gaattgaccg
     7801 ttccgccaac cttggttgcc tttggggtga cgacggcaga tagccgtaag gtgctctctc
     7861 cagaatttaa agctgttggg gaaaatatct actacatccc aggtcaagcc ctctctgcag
     7921 agattgattt tgacttgatt aagaaaaatt ttgctcagtt tgaagcaagc caagctgacc
     7981 ataaagtgac gtctgcatca gctgtcaaat acggtggtgt agttgaaagt ttggctcttg
     8041 ctacctttgg aaactatatt ggtgcagagg tgaccttgcc tgaacttaaa acagctttga
     8101 cagctcaatt aggcggcttt gtcttcacat ctcctgaaga aattgctgga gtagagaaga
     8161 ttggacaaac gaaagcagac tttacactga ctgtcaacgg tgtgaagcta gatggacaca
     8221 agcttgacag tgcatttcaa gggacattgg aagaagttta cccaacagaa tttacccaag
     8281 cgaaagaact agaagaagta ccagctgtgg catcagatgt tgtgattaaa gccaaagaaa
     8341 aggttgaaaa acctgtggtt tacatcccag tctttccagg aaccaactca gaatatgatt
     8401 cagctaaggc cttcgaaaaa gaaggtgcag aggtcaattt ggtgccattc gtgaccttga
     8461 atgaagaagc tattgtcaag tcagttgaaa ctatggttga caatatcgac aagactaata
     8521 ttctcttctt tgccggtgga ttctcggctg cggatgaacc agatggttca gctaagttta
     8581 tcgtcaatat cctgcttaat gaaaaagtgc gtgtggctat tgatagcttt atcgcccgtg
     8641 gtggcttgat tatcggtatt tgtaatggat tccaagcctt agtcaaatcg ggtctcctac
     8701 catacggaaa ctttgaagat gctaacagta ctagtccaac cctcttctac aatgatgcca
     8761 accaacacgt ggccaagatg gtggaaactc gcattgccaa taccaactca ccatggttgg
     8821 ctggtgtgca agtgggcgat atccacgcta ttcctgtttc gcacggtgaa gggaagtttg
     8881 tcgtgacggc tgaggaattt gcagagctcc gtgacaatgg acaaattttc agccaatacg
     8941 ttgactttaa cggtaaacca agtatggatt ctaagtacaa tccgaatggt tctgtccatg
     9001 ccatcgaagg aattaccagc aagaatggtc aaatcatcgg taagatgggc cactcagaac
     9061 gttatgagga tggtcttttc caaaatatcc caggcaataa agaccaacac ctgttcgcat
     9121 cagcggttaa acatttcact ggaaaataag acttacagat tttctaatag atagtatcag
     9181 taatgtaaaa gtcatgtaaa tctagctctt gatgattaca aatgaaaatt aggtataaaa
     9241 aatgacatac gaagtaaaat ctcttaatga agaatgtggt gttttcggta tttggggaca
     9301 tccagatgct gctaagttga cctattttgg actccacagt cttcaacacc gtggtcagga
     9361 gggggcagga atcctctcca atgatcaagg acaactgaag cgccatcgtg acatggggct
     9421 tttatcagaa gttttcagaa atccagccaa tttggataaa ttgacaggag ctggtgcgat
     9481 tgggcatgtg cgttatgcga ctgctggcga agcttctgtt gataacatcc agcccttcct
     9541 cttccgtttt cacgatatgc agtttggctt ggctcataat ggaaatctga ccaatgcagc
     9601 ctctctcaag aaagaactgg aacaaagagg agcaattttc agcgcgactt cggactctga
     9661 aatcttggct cacctcattc gtcgtagtca taatcctagc ctgatgggca aaatcaagga
     9721 agcgctcagc cttgtcaaag gtggttttgc ctatatcttg ctgtttgagg acaagttgat
     9781 tgcggctctt gaccctaatg gctttcgtcc gctttctatc gggaaaatgg ccaacggagc
     9841 ggtggttgtt tcctctgaaa cctgtgcttt tgaggtcatt ggtgccgagt ggattcgtga
     9901 tttgaagcca ggtgagattg tgatcattga tgacgagggc attcagtatg acagctatac
     9961 agatgatact cagttggcga tttgttctat ggagtatatc tactttgctc gccctgattc
    10021 taatatccac ggtgtcaatg tccatacggc acgtaagaga atgggagcgc aattggcgcg
    10081 agaatttaag catgaggcag atattgtagt tggtgtgccc aattcttccc taagcgcggc
    10141 tatgggattt gcggaagaat caggcttacc aaatgaaatg ggtctgatca aaaaccaata
    10201 cacccagcga acttttatcc aaccgactca agaattgcgg gagcaaggag tgcggatgaa
    10261 actgtctgct gtttcgggtg ttgtcaaagg caaacgtgtg gtcatggtgg atgattccat
    10321 tgtacgtgga acaacctctc gtcgtatcgt tcagctcttg aaagaagcgg gtgcgactga
    10381 ggttcacgtt gccattggaa gtcctgcact agcgtatcca tgtttctacg ggattgatat
    10441 ccagacccgt caggagctga ttgcagccaa tcatacggtc gaagaaactc gccaaatcat
    10501 tggtgcggac agtctgactt atctttcaat tgatggcttg attgagtcga ttggtatcga
    10561 aacagatgcg ccgaacggtg gtctctgtgt cgcttacttt gacggtgact acccaacgcc
    10621 tctctatgac tacgaagaag actatcgtag aagtttggaa gaaaagacca gtttttacaa
    10681 gtaggcgaca gattctccat taaagaaaag gaaaaaacaa atgacaaata aaaatgcata
    10741 tgcccagtcg ggtgtggatg ttgaagcggg ttatgaagtt gttgaacgga ttaaaaagca
    10801 cgtggcccgt acggagcgtg caggtgtcat gggagctctt ggtggctttg gtggtatgtt
    10861 tgacctttcc aagactgggg ttaaagaacc cgtcttgatt tcagggactg acggtgtcgg
    10921 aaccaagctc atgttggcta tcaagtacga caagcacgat accatcgggc aggactgtgt
    10981 ggccatgtgt gtcaacgaca tcattgctgc aggtgcggaa cccctctatt ttctcgacta
    11041 cgtagcgaca gggaagaatg aaccagctaa gctagaacaa gtggttgctg gtgtggcaga
    11101 aggttgtgtg caggctggtg ctgccctcat cggtggggaa acggctgaaa tgccgggcat
    11161 gtacggcgaa gacgactatg acttggctgg ttttgcggtc ggtgtggctg aaaaatctca
    11221 aatcattgac ggttcaaagg tggtagaggg agatgttctt ctcggacttg cttcaagtgg
    11281 gattcactca aatggttact ctttggttcg tcgtgtcttt gcggattaca caggtgagga
    11341 agtcctacca gaattggaag gcaagaaact taaggaagtt ctacttgagc cgactcgtat
    11401 ctatgtcaag gctgtcttgc cgctcatcaa agaagagttg gtcaacggca ttgcccacat
    11461 cacaggtggt ggctttatcg aaaatgtccc tcgtatgttt gcagatgacc tagctgctga
    11521 aattgatgaa agcaaagttc cagtgcttcc aattttcaaa gcccttgaaa aatatggtca
    11581 gattaaacac gaagaaatgt ttgaaatctt caatatgggt gtgggactta tgttggcggt
    11641 cagccctgaa aatgtagagc gtgtaaaaga attgttggat gaagcagtct atgaaattgg
    11701 tcgcatcgtc aagaaagaaa acgaaagtgt cattatcaaa tgaaaaaaat agcggttttt
    11761 gcctctggta atggctcaaa ttttcaggtg attgccgaag aatttccagt ggagtttgtc
    11821 ttttcagacc atcgtgatgc ctatgtgctt gagcgtgcaa agcagctcgg cgttctgtcc
    11881 tatgcttttg aactcaagga gtttgagagc aagacagact acgaagcagc ccttgtcgaa
    11941 ctcttggaag aacaccagat tgacttggtt tgcctagcag gctacatgaa aatcgttgga
    12001 ccaaccttat tgtcggctta tgaaggtcgg attgtcaaca ttcatccagc ctacttgcca
    12061 gaatttccag gagctcatgg gattgaggat gcttggaatg ctggcgtggg tcagtctggt
    12121 gtgaccattc actgggtgga ttcgggtgtg gatacaggcc aggtcatcaa acaggttcgt
    12181 gtgccacgac tagctgatga taccattgac agatttgaag ctcgcatcca tgaagcagag
    12241 tacaggttgt atccggaagt agtgaaggct ctatttacag attgactttt tgatgattca
    12301 tatgatatct ttgattttaa attggagtca gtgtttgttg aagacggctt caaacggagg
    12361 tatttgtaat gttagaatct aaaaaaacaa ctcgatatgt attttatgtc tatctgatgt
    12421 tattaacttg gggaatctta tttaagtttg aaacaaatcc tgaatttata gcatttttct
    12481 tagctccaag gtatatcaat tggattccat tttcagaacc actaatagtc gatggaaaaa
    12541 ttgtttttgc tgaaatgtta tttaatctga tttcctttat tccattaggt gtttgtttcc
    12601 ctttgataaa aactaattta tctagtttaa gaatagtcgg gacaggtttc ttgattagtt
    12661 tattgtttga gtgcttacag tatattttag caataggtat aacagatata acggatttga
    12721 ctttaaatac gctaggtgtc tgtgtaggct tactgattta tcaaattttt ataagagtgt
    12781 tcaaatcaca gactagaaaa tggatcaata tcttaggtat gcttagcctt ggttttgctt
    12841 atcttgtttt actgttactg catttaattg gtgtttaact aatgattaaa aaggagaata
    12901 taatgactaa acgcgtctta atcagcgtct cagacaaagc gggcattgtt gaatttgccc
    12961 aagaactcaa aaaacttggt tgggagatta tctcaacagg tggaactaag gttgcccttg
    13021 ataatgctgg ggtggatacc attgctatcg atgatgtgac tggtttccca gaaatgatgg
    13081 acggtcgtgt gaagaccctc cacccaaata tccacggagg gcttctcgct cgtcgtgact
    13141 tggatagcca cttggaagcg gctaaggaca acaagattga gctcattgac cttgtggtgg
    13201 tcaaccttta cccatttaag gaaactatcc ttaaaccaga tgtgacttat gctgatgcag
    13261 ttgaaaatat cgatattggt gggccatcta tgcttcgttc agcagcgaaa aatcatgcca
    13321 gtgttacagt tgtggtagat cctgctgact acgctgtggt tttggacgaa ttggcagcaa
    13381 acggcgaaac ctcttatgaa actcgccaac gtttagcagc caaagtattt cgtcacacag
    13441 cggcttatga cgccttgatt gcagaatact tcacagctca agtgggtgaa agcaagcctg
    13501 aaaaactcac tttgacttat gacctcaagc aaccaatgcg ttacggtgag aatcctcaac
    13561 aagacgcgga cttttaccag aaagctttgc ctacagatta ctctattgct tcagccaaac
    13621 agctcaacgg gaaagaattg tcatttaata atatccgtga tgcagatgct gctatccgta
    13681 tcatccgtga cttcaaagat agtccaaccg ttgtggctct caaacacatg aatccatgtg
    13741 gaattggtca agctgatgac atcgagactg cttgggacta cgcttatgag tctgacccag
    13801 tatctatctt tggtgggatt gtcgtcctca accgtgaggt ggatgctgcg acagctgaga
    13861 agatgcacgg cgttttcctc gaaatcatca ttgccccaag ctatacggat gaagcgctag
    13921 ctattttgat caataaaaag aaaaacttgc gtatccttgc cttgccattt aatgctcaag
    13981 aggctagcga agtggaagca gaatacacag gtgtagtcgg tggacttctc gtgcaaaatc
    14041 aagacgtggt caaggaaagc ccagctgact ggcaagtggt gaccaaacgt cagccaactg
    14101 agacagaagc gactgctctt gagttcgctt ggaaggctat caagtacgtc aaatcaaatg
    14161 gtattatcgt gaccaacgac cacatgacac ttggtgttgg tccaggtcaa accaaccgtg
    14221 tggcttctgt tcgccttgcc attgaccaag ccaaagatcg tctgaacggg gcggtccttg
    14281 cttcagatgc cttcttccca ttttcggata acgtggaaga aatcgccaaa gcaggaatta
    14341 aggccatcat ccagcccggt ggctctgtcc gtgaccaaga atccatcgaa gcagcgaata
    14401 aatacggctt gactatggtc tttacaggtg tgagacattt tagacattaa gaagataaaa
    14461 gggaagaaaa cagtttcttt ccttttttgg cttaaaatgc taactgaaac aagattaaaa
    14521 cgaacttttt tgatataatg ttggtaaata attcgcaaaa gaggttgagg aatgaaactg
    14581 cttgttgtcg gttctggtgg tcgtgagcat gcgattgcta aaaagttact tgaatcaaaa
    14641 gacgtggaaa aagtctttgt agctcctggg aatgatggga tgactctgga tggtttggaa
    14701 ttggtaaata tctctatttc cgaacattct aaattgattg acttcgcaaa gaccaatgat
    14761 gttgcttgga cctttatcgg tccagatgat gcccttgctg ctggtatcgt ggatgatttt
    14821 aaccaagctg ggcttaaggc ctttggtccg actagggctg cagcggagct ggagtggtcc
    14881 aaggattttg ccaaggaaat catggtcaaa tatggtgttt cgacagcagc ctatggcaca
    14941 ttttcagatt tcgaggaagc caaggcctat atcgaaaagc atggtgcgcc tatcgtagtc
    15001 aaggcggatg gcttggcgct tgggaagggt gtcgtcgttg ctgagacggt tgagcaagcg
    15061 gtcgaagccg ctcatgagat gcttttggac aataaatttg gtgactcagg tgcgcgcgtg
    15121 gttattgagg aattccttga aggagaggaa ttttcactct ttgcctttgt caatggtgat
    15181 aagttctaca tcatgccaac ggctcaggac cacaaacgtg cctacgatgg cgacaaaggg
    15241 cctaacacgg gtggtatggg tgcctatgcg ccagttccac acttaccaca gagtgtagtt
    15301 gatacagcgg ttgacaccat tgtcaagcca gttctagaag ggatgattaa agaaggtcgc
    15361 ccttatctag gtgtcattta cgcagggctt atcttgacag cagacgggcc gaaggtcatc
    15421 gagttcaact ctcgatttgg agatcctgaa actcagatta tattgcctcg tttgacctct
    15481 gactttgctc aaaatatcac agatatcctg gatagcaagg agccaaatat catgtggacg
    15541 gacaagggtg tgactctggg tgtggttgtc gcatccaagg gctacccgct agactatgaa
    15601 aggggcgttg agttgccagc caagacagaa ggcgatgtca tcacctacta tgcaggggct
    15661 aagtttgcgg aaaatagcag agcactgctc tcaaacggcg gacgagttta tatgctggtt
    15721 accacagtag ccaccgtcaa agaagcccaa gccagcatct accaagaact atcccaacaa
    15781 aaaatagaag gactcttcta ccgaacagat atcggaagca aggcaattaa gtaaagatat
    15841 aagaataacg cgacgcagtc gccaaacacg ataatggtcg tcgtggtgaa aagaccagaa
    15901 cagtgaatgt tctggtcagg gggaaacttt gagaccttag gctcaaagtt taggaatgaa
    15961 accgaaggtt tgcttccgcc tccatcacct aagaccatta tcaaaaagaa aaataaaaat
    16021 tcacaaaata cgttaatggt cgtatggttt gcgagcgtta gcgagcaaat atagaataat
    16081 caccgccgtt gtgaaagaac gattggatga taatccaatc gttcagggaa attggaagac
    16141 cttgggtttc caatttaggc atgagacacc tttggtggct gctgccgtcc ctcacaagct
    16201 aaggtgattg ttgaaaaaga ggaaaaagga gaagaaatga aaccagtaat ttccatcatc
    16261 atgggttcaa aatccgactg ggcaaccatg caaaaaacag cagaagtcct agaccgcttc
    16321 ggtgtagcct acgaaaagaa agttgtttcc gcacaccgta caccagacct catgttcaaa
    16381 catgcagaag aagcccgtag tcgtggcatc aagatcatca tcgcaggtgc tggtggcgca
    16441 gcgcatttgc caggcatggt agctgccaaa acaacccttc caatcattgg tgtgccagtc
    16501 aagtctcgtg ctcttagtgg agtggattca ctctattcta tcgttcagat gccgggtggg
    16561 gtgcctgttg cgaccatggc tatcggtgaa gctggagcga ctaacgcagc tatctttgcc
    16621 ctccgtctcc tctctgtaga agataagtcc attgcggatg cacttgccaa ctttgctgaa
    16681 gaacaaggaa aaatcgcaga ggagtcgtca aatgagctca tctaaaacaa tcggaattat
    16741 cggtggcggt caactgggtc agatgatggc catttctgct atctacatgg gccacaaggt
    16801 tatcgcgctg gatcctgcgg cggattgccc ggcctctcgc gtggcggaaa tcattgtggc
    16861 accttataac gatgtggacg ccctccgtca gttggcagac cgttgcgatg tcctcactta
    16921 tgagtttgaa aatgtcgacg ctgacggttt ggatgccgtt atcaaggatg gacaactccc
    16981 tcaaggaaca gatctgctcc gcatttcgca aaatcgtatt tttgaaaagg actttttgtc
    17041 aaacaaggct caagtcactg tggcacccta caaggtcgtg acttctagcc tagacttggc
    17101 agatatcgac ttgtcgaaaa actatgtcct caagactgcg actggtggct acgatggtca
    17161 tggacaaaag gttattcgtt cagaagcaga cttggaagca gcctatgcgc tagcagactc
    17221 agcagactgc gtcttggaag aatttgtcaa ctttgacctt gagatttctg tcatcgtgtc
    17281 aggaaatggc aaggaggtga cgtttttccc agttcaggaa aatatccacc gcaacaatat
    17341 cctgtctaag accatcgtac cagcccgcat ttctgaaagt ctagtagaca aggctaaagc
    17401 tatggcagtg cgaatcgcag aacaactcaa cttgtctgga actctctgtg tggaaatgtt
    17461 tgcgactgat gatgacgtta ttgtcaatga aatcgcccca cgaccacata actctgggca
    17521 ctattctatt gaagcctgtg atttctctca gtttgacacc catattctcg gtgttctcgg
    17581 agcaccatta ccagtcatca aactccatgc gcctgccgtc atgcttaacg ttctcggcca
    17641 gcatgttgag gccgctgaaa aatatgtcac agaaaattca agcgcccacc tccacatgta
    17701 tggtaaaata gaagcgaagc acaaccgcaa gatgggacat gtgactttga ttagtaatga
    17761 accagatagt gtggatgagc ttggggaagg gattgatttt taggacaagt ctatgataca
    17821 aattatcgtt aatacattta ttgaaaagga taagactgga gcagttgttg aagtgttgta
    17881 tgccagtgct gaccaagata aggtacaagc taaatatgaa gaactagctg cacaataccc
    17941 cgaaaattat ttagctatct atgatgtacc gctggatacg gatttgaata cactagatca
    18001 ttacccgtct gtgtttattg gaaaagagga gtttgagtag aaatcttggt ttacctagat
    18061 agcttattcc caacagctta agaagaaagg aaaaattaac acatgatcaa ccgttactct
    18121 cgccctgaga tggcgaatat ttggagtgaa gaaaataaat accgtgcttg gcttgaggtg
    18181 gaaatcctct ctgacgaggc atgggctgag ttgggggaaa tccctaagga agatgtggct
    18241 ttgattcgca agaaggcgga ctttgacatc gaccgtattt tggaaattga gcaggagacg
    18301 cgccacgatg tggtggcttt cacgcgtgcg gtttctgaga ctcttggtga agagcgcaag
    18361 tgggttcact atgggttaac ttctactgac gtggtggata ctgcttatgg ttacctctac
    18421 aagcaggcca acgacatcat ccgtcgtgac cttgaaaact tcactaatat catcgctgac
    18481 aaggccaagg agcacaagtt caccatcatg atggggcgta ctcatggtgt gcacgctgag
    18541 ccgacaacct ttggtcttaa attagcaact tggtacagcg aaatgaaacg caatatcgag
    18601 cgcttcgagc atgcggctgc tggtgtagaa gctggtaaga tttctggtgc ggttgggaac
    18661 tttgccaata tcccaccatt tgtagaggag tatgtctgcg ataaacttgg catccgtgcc
    18721 caagaaatct ctacacaagt ccttcctcgt gaccttcacg ctgagtactt tgcggttctt
    18781 gccagcattg cgacttcaat cgaacgtatg gcgactgaga ttcgtggtct acaaaaatct
    18841 gagcaacgcg aagtagaaga gttctttgct aaagggcaaa aagggtcttc agcaatgcct
    18901 cacaaacgca acccaatcgg ttctgaaaat atgactggtc tggcgcgtgt cattcgtggt
    18961 cacatgatta cggcttatga aaacgtcgct ctctggcacg aacgcgatat ttctcactca
    19021 tcagctgagc gtatcatcac accagatacg accattttga ttgactacat gctcaaccgt
    19081 tttggaaata tcgtcaagaa cttgacagtc ttcccagaaa atatgatccg aaacatgaac
    19141 tcgacttttg gtcttatctt tagccaacgg gctatgttga cattgattga aaaaggcatg
    19201 acccgtgagc aagcctatga cttggtgcaa ccaaaaacag cctactcttg ggacaaccaa
    19261 gtagacttta aaccacttct tgaggcagat tcagaagtaa catcacgtct cacacaagaa
    19321 gaaatcgatg aaatcttcaa cccagtttat tacaccaaac gagtggatga tatctttgaa
    19381 cgtcttggac taggtgatta attaaaaaat aaacagcgag cttcaatctc gctgtttatt
    19441 ttttatcgaa aagacttagt cttcttttct tttagtgagt ccataggctg ctagtgtgga
    19501 catgagtcct gcgactacta gtcctgcaga atcgtgagtt cctgtttcag gaagtttttt
    19561 ctctgttacc acaggagctg gatcttgagg aagagctttg ctttcctcag caggagcagt
    19621 tgatggagct ggttggcttg ggatttctag ttttggtttt tcttcagcaa tagcggcttg
    19681 tccgttttca tcgcctacat gtgttaccat agttccgact tcgactattt gagtaacggc
    19741 ttcctgtgct acgacactat ttacaagtgt tttcacttcc ttaccatcgg cagaagtgct
    19801 cacagagtag aagttgctac gatgtccatt gacgccctta gtaatgactt gtgtttttcc
    19861 tttgagtaag agtggatttt cacgagtcac tgtggtaaat ggaatttctt ctttttggat
    19921 atccagtcta ggttttacct cagtagttgg tgcaagacca ctttcatcac ccttgtgagt
    19981 tacaggagcg ccaacttcaa ccacttggtt tataacttct ttggttacct ggctatcaag
    20041 gactgtttct gttgtttttc cattttcagt gagtacagag atgtaatgag ttcgttcacc
    20101 tttgactcct gctgtgataa tattttcctg accagctggg aggttaggat tttctttctt
    20161 gataacttca aatggaattt cttcagttct tgtgatgagt tctggtctgg tttcaacatt
    20221 ggcagccact tcattttcat ctaggcttcc tgaatgagtt gcagctggtt tgaggccttg
    20281 aagagcggct tttaggttgg ctacaagtgt gtcaagctca gcttgtttat tacggttgag
    20341 gttgtaattt agagctgttt tagctgcgtc aagggcctca agactttctt tactatatcc
    20401 ttctaagttt gtaggaattt tagctaattc ttcgcggaga gcattataat tagcacggaa
    20461 gtagtctttg ttgtggtctg caaaggcagt catgagttca aagatttcct cttccttgta
    20521 ctcagcgctt ggtctatctg cccagattga aagcatactt ccaactgttg gaagatctac
    20581 ttcaggatat ttggtagaag ctagttgatt gaatggtgtt tttccagtat tctcaatagc
    20641 tttcttgagg aaaccaccac catcttctgg tttttgacca agaacataat accagtcacc
    20701 gttggtattc aagaacttat aacccttgct tgctaggtat tgaggtgatg cgaggttgta
    20761 tccccaccag cctttagacc agtaagaaat caagacatct ttgtcaaact gaacatcgtc
    20821 cttgtcttca tagtagaagc catcgttgaa ggccattggt tgaagccctc tttctttggc
    20881 catagctgcg agggtgttgg catattcggc aaatttgcca tagagttgat accacttgag
    20941 gtagtaccag ccttgggcac tagtcgcatc gttggcgtat tcgtcagtac caaagttgaa
    21001 aatctttgtt ttacctgcaa agaagtccat gtatttaccg atgagggctt ttacaaagtt
    21061 catcgcttct tcgtttttca agtccatagt tgtttttgaa actttatcaa agtgggcttg
    21121 aggattttta atacctaatt tttccatggc aaccagcata gcatccatgt gacctggact
    21181 gttaatagct gggatgagac cgatgtcctt agatttagcg tattcaatta gctctgttac
    21241 ttctgcctgt gttagtgcag taccgtttgg atcgtcgtag taagctttag ttccttcgat
    21301 aatagctttt ttaacgtcat cactagcata ggtttttccg ttggcagtaa tggtcatatc
    21361 atcgagtaga aagcgaagtc cgtcatttcc tagaaggaga tggacatcag aatatccgag
    21421 atcactggcc ttgtctacga tgcgtttgag ttggtccaga gtaaagtatt tgcgtccagc
    21481 atcgattgag attaccttgt ttttggcaag tttttcaacc tcacgtttag cttcttcttc
    21541 tttttgagct tcaggcgtga gggtcaagtt gttgacagtt tcttgaagtt tagcaatggc
    21601 ttgatcaatc gtatcttgtt gggcacggct aaggttgcta tcgagagagc gaatagcttt
    21661 ttcagcttct tttacggccg tgacgctttc tgcagtataa cggttcaggt cttttggtac
    21721 ctcgttaagt gcttgctctg cagattcata atcagctgcg aagtattcag cgttggcatt
    21781 tgcaaaatga cgcatgagtt tgaagaggcg tgatggtgaa taacgtgcag atggagtgtc
    21841 agtccaagca gctaccatac caccgatgat tgggatatca gctccttctg tttttggtac
    21901 agaagtgatt ggtgtgtttt taataccatt gagcccctga tcgagattgt accagccttg
    21961 gccatcagcg tttcgtccaa gaacgtagta ccaagcatca ttggtattaa ggatttggtg
    22021 acctttttca gctagtagtt tagaagaagc gacatcgtag cctccccaac caccagtcca
    22081 catagaaacg atgatgtctt tgtcaaaact accaaagctt gtgtcgctat tgtagtagat
    22141 accgtcgtta aaggccattg gtttgagacc gtgcgatttt acaatacgag cgaggtcatt
    22201 ggcgtaggca ataaattttt catagccttt tacagggtag ccttcgtttg gatagtattt
    22261 atcagcttga agcacactcc aacctttagc atctgtcgca tcattggcat attcatcaag
    22321 tccgatgttg aagatttcag tctttttcgc gaaataagca gcatacttgt cgataagggc
    22381 ttttgtaaaa gcgacagctt gttcgttgtc aagattgaca gtacgggctg attccttccc
    22441 aaaatagcta aagttagggt tttggattcc caattctttc atggcattga gaatcgcatc
    22501 catgtgacca ggactattta ctgtcggaat gagaccgata cctttatctt tggcatagtt
    22561 aatcagatct gtcatttgac tttctgttaa gtgattgccg tttggatcgt tgtaataatc
    22621 atttgtacct ttttcaatgg cgcgtttgac atcgtcactg gcataggtct tgccgttagc
    22681 tgtgatgctc atatcgtcca acatgaaacg gagtccatca tttccgacta ataggtgtaa
    22741 atcagtgtag ccataatgtt tcgctttatc gatgatttcc ttgagctgtt ctggtgagaa
    22801 atatttacgt ccagcatcaa tagaaacaat tttctttttc gctagttttt catttacagt
    22861 tgcagcacgt tcctttcctg cctctgtttc cggtttgtca gcctctgctt tcgcttcatc
    22921 ttttttagct ggtttatcct tgtcagtctt gtctgtattt gactctttag aatcaacctc
    22981 tttcgcttct tcctttttag ggctagcttc ttctgccttt ttattagcag tttctttttc
    23041 agcagaagtt ggagttacca cctctgcttt atcactagga gttgaactaa cttcctcttg
    23101 tggtttttct tctgtttttg gaagactagc taccttatca gtagctggag tttctgtttc
    23161 tacagttttt ggagcttctg gttgaagctc tgctttaggt gtttcctcag tccgattttc
    23221 ggatgattga ggggaatcag aaaccgtatg gatggtcggt tggttttctg tagtagtagg
    23281 agtaactcca tcggctgcaa cagtctgtgc ttggaaggca aatccaatta gaacagaagc
    23341 tgctcctaca gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt tcattgcaaa
    23401 acctcctgat tgcattgtta tattgatagc gattatataa atcaacgcct ttattttatt
    23461 tcttatatta acgagagtca agaggagatg acaaaaaact ataataagta taaaaaaata
    23521 taaaatttaa acttaagatt tcagattggt cggaaaaaat gaatatatat atctagtata
    23581 atttttggtt ctatttctat aaaatattcc acaaattata gaatcttcca aaaataggta
    23641 agcgctacct ttttggtgtg gtataataag catagaaaaa gcccaagcga ttagctcagg
    23701 ctttcttctt agtgatcacg gtcacatgag ataaatttaa tcttgtagta atcagatcgt
    23761 ttgtaagttt cactgtattc taaaacttgg ccagttgatt cgagtttggt gattttagtt
    23821 tgtaggacag tagggaattg ttcatcgact ccgaggactg aagccgcatg ttctggagtt
    23881 ggaaagacta tttcgttgat ttcttcaaag tgttcatcat tcatgtgaat gtggtagtct
    23941 aacttgaaac gattatagat agaactatag tattcaaggt ttggataatt tgcgttgata
    24001 tattgttctg ggatgtagga tgtatggtag atataaacga caccgtttga ttcgcggata
    24061 cgttcaatct tgtagtagaa ttgatcgccg cgtagaccca atttttccaa gtaaacaagc
    24121 ttgtttccgc gttcaattga aagaacagtt accttatcat ctttagcatt gaagagttca
    24181 atatctgaaa actctacaag cttgtgtttg cgcgcacgtg aaacgaaggt tccttttcct
    24241 tgttggcgga caatatagcc atctttggca aggtcgttta aggcgcgaac aactgtgata
    24301 gagctgacat cgtacattga aatgagttct gcttcagtgt aaaatttatc tccactgcta
    24361 aactgcccag agatgatttt attttttaat tcgtctttta tgtattgata tttgggaatt
    24421 gccatatttt tacctctatt ttccttctcc atagaaaatt ttaccataaa agcgaaaaaa
    24481 atagtagtct tttgaataaa aaattagaat aatagtttga aaaattaagc gatataggga
    24541 ttgctcatat tttataaatg tattctatac aaaattattt taggtcctat attccgaatt
    24601 taaagagcgt ttgaaatggg tctaaaaatg tttgaaacta attgaatgtg tgtataatag
    24661 taaaaatgca gtaaatatcc cgacaatttc tattgacaat tcaaacagat tggtttataa
    24721 ttaatataac aacaaatgaa agcgcaaact ttcgcggtcg gaaggtagtt ttatgacacg
    24781 atttgagata cgagatgatt tctatctcga tggaaaatca tttaagattt tatctggtgc
    24841 cattcattat tttagggttc ctccagagga ttggtatcat tcgctctata acttgaaggc
    24901 tcttggtttt aatacggtag agacttatgt tgcttggaat ttacacgagc ctcgtgaagg
    24961 tgagtttcat tttgacggtg atctggattt agagaaattt ctccaaatag cgcaggattt
    25021 gggtctctac gcaattgtgc gtccgtctcc atttatctgt gcggaatggg aattcggtgg
    25081 cttaccagct tggctcttga ccaagaacat gcgaattcgc tcatccgacc cagcatatat
    25141 cgaggcagtt ggtcgctact atgatcagtt attgccaaga ctggttcctc gtttgttgga
    25201 caatggtggc aatattctca tgatgcaggt tgaaaatgag tatggttctt acggagaaga
    25261 taaggcttac ctgagagcga ttcgacagct aatggaagag tgtggcgtaa cctgtcccct
    25321 ctttacatca gatggtccat ggcgagctac tctgaaagct ggaaccttaa ttgaagagga
    25381 cctctttgta acaggaaact ttggttctaa ggcaccttac aacttttcgc agatgcagga
    25441 attctttgat gaacatggta agaaatggcc actcatgtgt atggagttct gggatggttg
    25501 gtttaatcgt tggaaagaac cgattatcac acgggatcct aaggaattgg cagatgcagt
    25561 tcgagaagtt ttggaacaag gctccatcaa tctttacatg ttccacggtg gtacaaactt
    25621 tggtttcatg aatggttgct cggctcgagg aactttggac ctgccacaag ttacgtctta
    25681 tgattacgat gcccttctgg atgaagaagg aaatccaact gctaaatatc ttgcagtcaa
    25741 gaagatgatg gcaacacatt tttcagagta tccgcagttg gaaccactct acaaagagag
    25801 tatggagttg gatgctattc cactagttga aaaagtttct ttgtttgaaa ccttagatag
    25861 cttgtcaagt cctgtagaaa gtctctatcc tcaaaagatg gaggagctgg gacaaagtta
    25921 tggctaccta ctttatcgaa cagaaacaaa ctgggatgca gaagaagaaa gacttcgtat
    25981 cattgatggt cgagataggg cccagctgta tgtcgatggt cagtgggtta aaactcaata
    26041 tcagacagag attggggaag atatttttta tcaaggtaaa aagaaagggc tatctaggtt
    26101 agatatcttg atagaaaata tggggcgtgt caactatggg cataagttct tagcggatac
    26161 gcaacgtaag ggaattcgga caggggtctg taaggatctg catttcttac taaactggaa
    26221 acactatcca ctcccactag acaatcctga gaaaattgat ttttcaaaag gatggactca
    26281 aggacaacca gccttttacg cttatgactt tacagtcgaa gagccaaaag atacttacct
    26341 agacttgtct gagtttggta agggggttgc ctttgtcaat gggcagaatc taggacgttt
    26401 ttggaacgtt ggcccaactc tctcacttta tatccctcat agctatctca aggaaggtgc
    26461 caaccgcatc attatctttg aaacagaagg tcaatataaa gaagagattc atttaactcg
    26521 taaacctaca ctaaaacata taaaggggga aaacttatga caattgtagg atgccgtatt
    26581 gatggacgtt tgatccacgg acaagtagcc aatctttggg ctggaaaact aaatgtttca
    26641 cgcattatgg ttgtagacga cgaagttgtc aacaacgata ttgaaaagag tggtttgaaa
    26701 cttgcgacac caccaggtgt gaaattgagt attttgccag ttgagaaagc tgcagccaat
    26761 attcttgctg gcaaatacga tagccaacgt ctctttatcg tggctcgtaa accagaccgc
    26821 ttccttggtt tggtagaagc aggtgtacca cttgaaaccc ttaatgttgg gaatatgtct
    26881 caaacaccag aaactcgttc tattacacgt tctatcaacg tagtagacaa ggatgtggaa
    26941 gacttccaca aactggcaga aaaaggtgtt aaacttactg ctcagatggt tccaaatgat
    27001 ccaatttcag actttttgag cttattaaaa taggaaaaaa ttttttagga ggtcattgtt
    27061 atgatacaat ggtggcaaat tttacttctc actttgtact cagcttatca aatctgtgat
    27121 gagttgacga tcgtttcatc tgcaggttcc cctgtatttg ctggtttcat tactggttta
    27181 atcatgggag atgtgactac tggtttactt atcggtggta acttgcaact gttcgttctt
    27241 ggggttggta ccttcggtgg tgcttctcgt atcgacgcaa cttctggtgc ggttcttgcg
    27301 acagccttct ctgtttcaca aggaattgat gcaccgcttg caattactac aatcgctgta
    27361 ccagtagcag ctctcttgac ttacttcgac gttcttggtc gtatgactac taccttcttc
    27421 gctcaccgtg tggatgctgc aatcgaacgc tttgactata aaggtattga acgcaactac
    27481 ttgcttggtg cgattccgtg ggctctatct cgtgcccttc cagtcttctt tgcccttgct
    27541 tttggtggtg cctttgtaca atcagtagta gacttcgttg aagcctacaa atgggttgca
    27601 gatggcttga cactcgcagg acgtatgctt ccaggtcttg gatttgcaat cttgcttcgt
    27661 taccttccag ttaaacgtaa ccttcactac cttgctatgg gatttggttt gacagctatg
    27721 ttgactgttc tttactcata tgtaacaggt cttggtggcg ctgttgctgg tatcgtaggt
    27781 actcttcctg ctgaagttgc tgaaaaaatt ggtttcgtga acaacttcaa aggtttgtct
    27841 atgattggta tttctatcgt aggtattttc cttgcagtgc ttcacttcaa aaatagccaa
    27901 aaagtagctg tagcagcacc ttctacacca tcagaaagtg gggaaatcga agatgacgaa
    27961 ttctaattac aaacttacaa aagaagattt taatcaaatc aacaaacgta gcttgtttac
    28021 tttccaatta ggttggaact acgaacgtat gcaagcttct ggttaccttt acatgatctt
    28081 gcctcagttg cgtaaaatgt atggtgatgg aactcctgaa ttgaaagaaa tgatgaaagt
    28141 tcatactcaa ttcttcaata cttcaccatt cttccatacc attatcgctg gttttgacct
    28201 tgccatggaa gaaaaagatg gtgtaggttc aaaagacgct gttaacggta tcaagacagg
    28261 tttgatggga ccattcgctc ctcttgggga tacaatcttt ggttcacttg tacctgctat
    28321 catggggtca gtcgcagcaa ctatggctat cgctggccaa ccttggggga tcttcctttg
    28381 gattgcagtt gcagtagcgt atgacatctt ccgttggaaa cagttggaat ttgcttacaa
    28441 agaaggggtt aaccttatca acaacatgca aagtaccttg acagctttga ttgacgctgc
    28501 atctgtactt ggtgtcttca tgatgggtgc tcttgtagca acagtgatta actttgaaat
    28561 ttcttacaag ttgccaatcg gtgaaaagat gattgatttc caagacatct tgaaccaaat
    28621 cttcccacgt ttgcttccag caatctttac tgcctttatc ttctggttgc ttggtaaaaa
    28681 aggtatgaac tctactaaag ctatcggtat tattatcgta cttgctttgg ctctttctgc
    28741 ccttggtcac tttgcacttg gaatgtaatt ccttatgact aaatcattaa ttttggtgag
    28801 ccatggtcgc ttctgtgagg agcttagagg tagcacagaa atgattatgg gcccacaaga
    28861 caacatttac acagtagctc ttcttccaga agatggccca gaagaattta ctgctaaatt
    28921 tgaagctgtt attgaaggat tggatgattt cctagtcttt gcggatcttc tcggtgggac
    28981 accttgtaat gtggtgagtc gcttgatcat ggaaggtcgt gatattgacc tttacgcagg
    29041 gatgaatctt ccaatggtga ttgaatttat caatgcgagc cttacaggcg cagatgcgga
    29101 ctacaagagc cgtgctgcag aaagcattgt gaaagttaat gacctgttag cgggcttcga
    29161 tgatgacgaa gatgaataat actcttcgaa aatctcttca aactacgtca acgtcgcctt
    29221 gccgtaggta tatgttactg acttcgtcag tcttatccgg caacctcaaa gcggtgcttt
    29281 gagcagcctg cggctagttt cctacagatt ttagttggaa ctcgattcaa ttcatgtgac
    29341 aacgtgaaaa tcgttagagc attttatata gaatatacat gggaatggag cttactccca
    29401 ttcccatatt taatagaaaa agaggaactc aatgctacat tatacaaaag aagacttgct
    29461 cgaattgggt gcagaaatca ctacgcgtga aatctaccaa cagcctgatg tatggagaga
    29521 agcttttgaa ttttatcaag caaaacgtga agaaattgca gcctttctac aagaaatcgc
    29581 tgataaacat gactatatta aggttatctt gacaggtgct gggacttctg cttatgtggg
    29641 agataccttg ctaccttact ttaaggaagt ctatgacgaa cgcaaatgga atttcaatgc
    29701 tattgcgaca acagatatcg ttgccaaacc agcaacctat ttgaaaaaag atgtggcaac
    29761 tgtccttgtg tcttttgctc gtagtgggaa ctcgcctgaa agtgtggcga ctgttgattt
    29821 ggccaaatcc ttggtggatg agctttatca agtgacgatt acttgtgcag cagatggtaa
    29881 attggctctt caagctcacg gtgatgaccg taatctcttg ctcttgcaac cagctgtctc
    29941 taatgatgct ggatttgcca tgacttctag ctttacgtct atgatgttga cagctctctt
    30001 ggtctttgat cctacagaat ttgctgttaa gtctgaacgt tttgaagttg tatctagtct
    30061 tgcccgtaaa gttttagaca aggtagaaga tgtcaaagag ctcgttgatt tagactttaa
    30121 ccgtgtcatc tatctaggcg ctggtccttt ctttggactt gctcatgaag ctcagctcaa
    30181 gattttggaa ttaactgctg gtcaagttgc gaccatgtat gaaagcccag ttggcttccg
    30241 tcacggtcca aaatctctta tcaacgacaa tacagttgtt ttggtctttg gtacaacgac
    30301 agcctacact cgtaagtacg acttggactt ggttcgtgaa gttgctggtg accagattgc
    30361 tcgtcgtgtt gtgcttttga gtgatcaagc ttttggtctt gaaaatgtca aagaagtggt
    30421 ccttggttgt ggcggtgtct tgaatgatat ttaccgtgtc ttcccttaca tcgtttatgc
    30481 ccaactcttt gctctattga cttcactcaa ggtagaaaat aaaccagata caccgtctcc
    30541 tacaggtaca gtaaaccgtg tagtacaagg tgtcataatt cacgaatatc aaaagtaaga
    30601 cagtgtttat gaattcttga caagaggatt tgtaaattat cagataaacc atagattgtc
    30661 agtacgcttt ctatggtttg tttgcttgag agaaatagta aaaggagaac agaatgaaag
    30721 catacacaga gcgtgtattt ggaaatgttg agggcgagga tgtcttggcc tatcgatttg
    30781 agacagacgg tggctaccaa cttgaggtta tgacttatgg cgcgaccatc ttgcgctatg
    30841 tcgcacctga caaggctgga aattttgcca atgttatctt gggatttgat gactttgata
    30901 gttatgtagg caatagtccc aagcatggag caagtgtagg tcctgtagcg ggtcgtattg
    30961 caggtgcgac ctttgagctc aatggtaaga cctatgacct tgaggttaat aatgctagca
    31021 actgtaatca cagtggttca actggttggg attccagctt gtttgaagtt gaagaagtaa
    31081 gcgatcatgg cttgactctc tacacagagc gtacagatgg gacaggaggg ttccctggaa
    31141 atctcaagat ttggatcagt tatcacttgg aagaaactgg tgcctatgaa atcatctaca
    31201 aggtaacgac cgatcaggat acgctggtca atccaaccaa ccacagctat ttcaacttgt
    31261 ctggtgattt cacgcagacg attgaccgtc atgtcttcca actaaacaca gagggcattt
    31321 actcaatcgc tcctgacggt gttcctgcca aaactccaga agccaaccgt gatgtggtca
    31381 aacacatcta caatggtacc ttgttgaagg atatctttgc agaagaagat gagcaaatcc
    31441 agctggcatc aggtttggat cacccatttg cccttcctgc aggccatgac aatgctggat
    31501 tcctttatga ccaaaattca ggtcgcttcc tgcttttcaa gacagaagct ccttgctttg
    31561 tggtctacac agcaaacttt gtggatgaaa gtgtcatcat aggaggtcag ccaatgctac
    31621 agcacaatgg gattgctctt gaagcgcaag ctttaccaga tgccattcac agtgacctta
    31681 aaggccaagt cattcttaaa gctggtcaaa ccttcaccag taagacacgt tatgaacttg
    31741 ttgtgaaata aaaaaagctg gtcaaaaagt ctttaaaatt aaaataacgc atattgtcag
    31801 gtgatgaaaa gtttgataat atgcgtttta ttatgaaatg atttacttta tcttatcctg
    31861 aaatggtgtt atttttgagt tatctggctt gactttcttg atggaaatta tataatagtt
    31921 gtaataacaa taattacaac gagaaaagag gaccatttat gacctatgaa tacaagagtc
    31981 acatttattt ggcagagaca gttttaaatg taaaggattt ggccagtcaa acagcctttt
    32041 atcagcaagt tattggttta gaaatcttat ctcaaactga gacagagtcc attctaggcc
    32101 ttggtggaaa agtcttggta cagctgattc aagcacaaga gagcggagaa gtgagggaac
    32161 attatggtct ttaccatttg gccattctct tgcccacacg caaggctttg gctgatgtct
    32221 tgaaacacct gacagatttg caaattcctc ttgtcggcgg tgcagaccat ggttacagtg
    32281 aagctattta cttggaagat ttggagggaa atggcattga actctatcga gataagccag
    32341 tttccacatg gaatattcga gaagatggac gcattatcgg agtgacggag gctcttgcgg
    32401 cgcaggacat ttatgagttg ggggaaagag tagagccctt tatcctggca gaaggtacaa
    32461 gaatggggca tattcatctt tccgtcaagg atagtcgaaa gtccagccag ttttatcaaa
    32521 aggtgttagg gctagagaat aaattcagtg tgcctggcgc tagttggatt gcggctggag
    32581 attaccatca tcatttagca gttaacgaat ggggaggaaa aggtctggct tcgcgtaagc
    32641 aaggcttacc aggtttagcc tactatgtca tcgaagtcgc acataaaaaa gaactgttaa
    32701 cgattgccca acgagcacaa gaagttgacg caccaatcaa atggatgaca tcgatccaat
    32761 tggaaatcac agactcagat ggcatcgtga cccgtattcg tttagcaagg taaaattagg
    32821 aatttttaat aagttataag tattgctagt ttgctttttg aacggtcttt ggtaacagaa
    32881 ctgcgtgagc tggatgggtg agaattttga caaagaagct gattagagat ataatgaaga
    32941 aaaatcgagc aaggaaaaag aaatgacaaa ttcaaagtat attacttgtt tgaaacgttc
    33001 agagggccag ttgtgtggga ttcaaaagat gattgaagga gattgtgact gtgctgatat
    33061 tgtgacgcaa ctgacagcag tgagatctag tgtagagcgc gtgattgaga tgataattac
    33121 cgaaaatctt actgaatgta tcaatcagcc actagatgat tctgaagctc aaaaggaacg
    33181 cctagaaaag gctatccgat acttgattaa acggaaataa atgaatgttt tgagacgata
    33241 tgtgcaaagg tctattaact attagaatag tttaatgtga gtcaaaagaa gttgtaaaaa
    33301 atctttaaaa ttaaaaaaac gcatagtatc aggtgttgaa tgtattgacc ccaaaaagtt
    33361 agattttttc tgtctaactt ttggggtgca gttcataaga accttggtaa tatgcgtttt
    33421 attatgtaga gacttatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc
    33481 gtagatatgg ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct
    33541 gacttcgtca gttccatcca caacct
//
LOCUS       DBEROT010000024        33045 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.24, whole genome shotgun sequence.
ACCESSION   DBEROT010000024 DBEROT010000000
VERSION     DBEROT010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.24"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(331..1179)
                     /gene="dprA"
                     /locus_tag="ACL8CG_001257"
     CDS             complement(331..1179)
                     /gene="dprA"
                     /locus_tag="ACL8CG_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGS1343852.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1275..1964)
                     /locus_tag="ACL8CG_001258"
     CDS             complement(1275..1964)
                     /locus_tag="ACL8CG_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGS1343853.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVCLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1976..2854)
                     /locus_tag="ACL8CG_001259"
     CDS             complement(1976..2854)
                     /locus_tag="ACL8CG_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1343854.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2844..3713)
                     /gene="licA"
                     /locus_tag="ACL8CG_001260"
     CDS             complement(2844..3713)
                     /gene="licA"
                     /locus_tag="ACL8CG_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGS1343855.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            complement(3730..4752)
                     /locus_tag="ACL8CG_001261"
     CDS             complement(3730..4752)
                     /locus_tag="ACL8CG_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGS1343856.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4757..5464)
                     /locus_tag="ACL8CG_001262"
     CDS             complement(4757..5464)
                     /locus_tag="ACL8CG_001262"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGS1343857.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5800..7287
                     /gene="tacF"
                     /locus_tag="ACL8CG_001263"
     CDS             5800..7287
                     /gene="tacF"
                     /locus_tag="ACL8CG_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGS1343858.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7297..8100
                     /locus_tag="ACL8CG_001264"
     CDS             7297..8100
                     /locus_tag="ACL8CG_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1343859.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8102..8911
                     /locus_tag="ACL8CG_001265"
     CDS             8102..8911
                     /locus_tag="ACL8CG_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1343860.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9186..12362)
                     /gene="carB"
                     /locus_tag="ACL8CG_001266"
     CDS             complement(9186..12362)
                     /gene="carB"
                     /locus_tag="ACL8CG_001266"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGS1343861.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12675..13754)
                     /locus_tag="ACL8CG_001267"
     CDS             complement(12675..13754)
                     /locus_tag="ACL8CG_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGS1343862.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13804..14727)
                     /locus_tag="ACL8CG_001268"
     CDS             complement(13804..14727)
                     /locus_tag="ACL8CG_001268"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGS1343863.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14746..15267)
                     /gene="pyrR"
                     /locus_tag="ACL8CG_001269"
     CDS             complement(14746..15267)
                     /gene="pyrR"
                     /locus_tag="ACL8CG_001269"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGS1343864.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15478..16107)
                     /gene="nth"
                     /locus_tag="ACL8CG_001270"
     CDS             complement(15478..16107)
                     /gene="nth"
                     /locus_tag="ACL8CG_001270"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGS1343865.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16107..16649)
                     /locus_tag="ACL8CG_001271"
     CDS             complement(16107..16649)
                     /locus_tag="ACL8CG_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGS1343866.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16819..17136
                     /locus_tag="ACL8CG_001272"
     CDS             16819..17136
                     /locus_tag="ACL8CG_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS1343867.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYDHVKHVLSLYGPV
                     FEF"
     gene            17375..18934
                     /locus_tag="ACL8CG_001273"
     CDS             17375..18934
                     /locus_tag="ACL8CG_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1343868.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRLLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(18978..19877)
                     /gene="htpX"
                     /locus_tag="ACL8CG_001274"
     CDS             complement(18978..19877)
                     /gene="htpX"
                     /locus_tag="ACL8CG_001274"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGS1343869.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19879..20439)
                     /locus_tag="ACL8CG_001275"
     CDS             complement(19879..20439)
                     /locus_tag="ACL8CG_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGS1343870.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20533..21246
                     /gene="rsmG"
                     /locus_tag="ACL8CG_001276"
     CDS             20533..21246
                     /gene="rsmG"
                     /locus_tag="ACL8CG_001276"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGS1343871.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            21500..22783
                     /locus_tag="ACL8CG_001277"
     CDS             21500..22783
                     /locus_tag="ACL8CG_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGS1343872.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(22978..24549)
                     /gene="ffh"
                     /locus_tag="ACL8CG_001278"
     CDS             complement(22978..24549)
                     /gene="ffh"
                     /locus_tag="ACL8CG_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGS1343873.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVCHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNVF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(24561..24893)
                     /locus_tag="ACL8CG_001279"
     CDS             complement(24561..24893)
                     /locus_tag="ACL8CG_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGS1343874.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(24984..25361)
                     /locus_tag="ACL8CG_001280"
     CDS             complement(24984..25361)
                     /locus_tag="ACL8CG_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGS1343875.1"
                     /translation="MKIRMRNTIQFDEQLEVIDRLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            25433..26737
                     /locus_tag="ACL8CG_001281"
     CDS             25433..26737
                     /locus_tag="ACL8CG_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGS1343876.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSLIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            26750..27556
                     /gene="yidA"
                     /locus_tag="ACL8CG_001282"
     CDS             26750..27556
                     /gene="yidA"
                     /locus_tag="ACL8CG_001282"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGS1343877.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            27599..28597
                     /locus_tag="ACL8CG_001283"
     CDS             27599..28597
                     /locus_tag="ACL8CG_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003712 - transcription coregulator
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HGS1343878.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(28764..28835)
                     /locus_tag="ACL8CG_001284"
     tRNA            complement(28764..28835)
                     /locus_tag="ACL8CG_001284"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28800..28802),aa:Arg,seq:cct)
     gene            complement(28877..29224)
                     /gene="rplS"
                     /locus_tag="ACL8CG_001285"
     CDS             complement(28877..29224)
                     /gene="rplS"
                     /locus_tag="ACL8CG_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGS1343879.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(29343..29672)
                     /gene="crcB"
                     /locus_tag="ACL8CG_001286"
     CDS             complement(29343..29672)
                     /gene="crcB"
                     /locus_tag="ACL8CG_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS1343880.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(29666..30040)
                     /gene="crcB"
                     /locus_tag="ACL8CG_001287"
     CDS             complement(29666..30040)
                     /gene="crcB"
                     /locus_tag="ACL8CG_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS1343881.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(30037..30303)
                     /locus_tag="ACL8CG_001288"
     CDS             complement(30037..30303)
                     /locus_tag="ACL8CG_001288"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGS1343882.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(30419..30862)
                     /locus_tag="ACL8CG_001289"
     CDS             complement(30419..30862)
                     /locus_tag="ACL8CG_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGS1343883.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            30966..31901
                     /locus_tag="ACL8CG_001290"
     CDS             30966..31901
                     /locus_tag="ACL8CG_001290"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGS1343884.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            31997..32239
                     /locus_tag="ACL8CG_001291"
     CDS             31997..32239
                     /locus_tag="ACL8CG_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGS1343885.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(32296..32514)
                     /locus_tag="ACL8CG_001292"
     CDS             complement(32296..32514)
                     /locus_tag="ACL8CG_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343886.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(32511..33045)
                     /locus_tag="ACL8CG_001293"
                     /pseudo
     CDS             complement(32511..33045)
                     /locus_tag="ACL8CG_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT        10024 a         7125 c         6032 g         9864 t
ORIGIN      
        1 tcactatact ttcccttata ctcaatgaaa agcaaagcgc aaactaggaa gctagccaca
       61 ggttgctcaa agcactgctt tgaggttgta gataagactg acgaagtcag ctcaaaatac
      121 tgttttgagg ttgcagatgg aagctgacgt ggtttgaaga gattttcgaa gagtattata
      181 tgagaaaaat cctctactct actaatccac ttagaaaaaa cgcatattat caagtgttaa
      241 aaacttgcta atatgcgttt tattatggaa atgttgggtt cattttctct taaaattgat
      301 tttttcttag aattctagct taggtcattt ttaaaattca aattccgcaa gaacatcttg
      361 cccactggtg accaattttg ctccttcttg aatcaaatga tggcaaccgt ctgatagtcc
      421 atctaaaatg ctaccaggaa tagcaaagac atcgcgtcct tcttccattg ctcgctcaca
      481 cgtaatgaga ctacctgaac gcatcttagc ctctgctaca atcacaccac gacaaagtcc
      541 agcaatgatg cgattacggg caggaaaatg aaatttcaga ggttgttcgc caggtccata
      601 ttcacttaga accagatggt cattgccgat gtagtcttgc aagcgtttat tggctttagg
      661 ataaaacaca tccagtcctg ttccaatcac tgcaatggtt tttccgccat tctgaagagc
      721 tgccatatga gctgctgtgt caatgccctt ggccagacca ctgacaataa ccagttcatt
      781 ttccaagcct tgaatgactt tttcaactga cttagctccc tgtttgctac aagcacgact
      841 gcccacgacc gctaccttcg ggaatttcag gaggtcaaga tttcccttgt aaaataaaag
      901 tacaggcgca tcatatattt cactcaaatc ccaaggataa cagtcatcta aaatagagaa
      961 agatggaaat ttttgaaact ctttcgacaa atgcgcatcg tctatctgaa aataacgttc
     1021 cataaaaacg gctggattac ggcaacctga tatatctgca atatcaccca acaaaagctc
     1081 ctgatcaaca ttttcaccgt attctagcac tttcaaaatc tgttgattgg tcaaacctga
     1141 tttttttaac ttatagattt catagtttgt gattttcata aataactcca tttctttttc
     1201 tactcatcta tctattcgta aaagttcgta aaaaatcaaa aaacatccga ctattttgtc
     1261 agatgttgga atctttaatt ttcgttttta agaatttctt ctaatttacg atagtcttgg
     1321 acactatcga tctcataaat gctattgcct tctaattctt caacatagac atctagctct
     1381 ttgatattat ccttaaccat attgtcccaa tagagatcaa caaattcacc acttgcataa
     1441 gccttgtcga taaagctgac aatcttttct gcagttggag catcccagaa ggatacacca
     1501 ctaaggatgc gacctgcctt gctatcaaca ataatgtctt gaaccttgta gtcatctcca
     1561 tagaccaaga accattcgtt ggtacaatct tcacgataaa cactaaaata agtcgaacga
     1621 gtcaaatcat tgcggaacat atttttaaag agatagttat ctgcatcaat aacatagctg
     1681 ttggccaatt cttcttttac aagatagaga gagtaaaagt tattgtagtc agcgtattta
     1741 tcattgaaaa cgaggcaaac accgtatttt tcttttaaat aatcgaattg ttctttaaga
     1801 taaccaacga tgatgatgat gtcattgatt cctttttctt tgagaaactc aatttggtat
     1861 tcaatcaaag gtttttgatt aacctgaacc aaggctttag gggtattttc agtcatagga
     1921 cgcaagcgag ttcccaatcc cgctgctaag ataatggctt tcacacgaat ctcctttatt
     1981 ctttaataat aatataaact ccagcaatga cgacaagtga cgtcataatg gtcagcatat
     2041 ctaatgatgt tcccaagaaa agagctgcga acaagacagt ccatactaca tagctcacgt
     2101 tcaagcctgt agccttggct ggttgcaagc gattgatagc gatataataa gccaagtagg
     2161 aaatcatatc aaaggctgca aaaacaatca tgagacctag caattgtcca ttggctactg
     2221 cagtaaatga ctgatgagag aagagcacaa tcacaagata ggacaagaac gaagttactt
     2281 gacggattaa gagggcttcg atttcactca attcactttc catggcaaaa gagctaagaa
     2341 cactctcact tccccatgca atagcacaaa ccaaagcaca aagaatccca atgtagaaag
     2401 aattaacctg ttcaacctta taggtctgag caataatccc tccaataatc aagacaatcc
     2461 caaatacagt atttttcgaa atcttgtgct tcaaaaagaa gaaagccaat agaactgaaa
     2521 tcgcagggta aatagccgat acagatgaag ctaaagaact tccgatatac ttaactgcat
     2581 aaagattggc ctgcataccg atagggcctg ctagcaaggc tccgatgata acactgacat
     2641 tgcgaatatt taagaaaatt gagaggcgaa ctttcccttc ttttaccaag agaaaagcta
     2701 gtaagataaa gatgctcaaa aaatcatgag ttgcagccac cacaaagggt gacaaatctg
     2761 taaaaatcga aaagatataa gcactaaccg ttagacccaa gccccagaaa atacctgaga
     2821 gaaggccaaa aggaactccg tttttacttt tcatctgaac ctccataaga agccaaacct
     2881 ttaatagctc tttggtaacg attcacacca tagtcaccaa aatcttcacc ttgctcttcc
     2941 ttatagacag tccatagact ccaaatagta tcttgtaaaa ttttataaat agcaatcttt
     3001 tcatgagaaa ccggtgtttg gtcactctca tagtgagata agaaagtttc ttcctcttgg
     3061 gaagtgaatt cagactctaa aaagagggca gccaaatccc acattggatc attcattgat
     3121 gaatattccc agtcaatcaa ataaagtcgt ccttgaggtg attcgataaa gttttcaggc
     3181 accaaatcga tatgacaaga ttttctgtca acacctaagt cagccagtct tttctctaag
     3241 gagaagactg catttctaac agattcatag ttggcataag gaatttgttc ttcaatcaag
     3301 gattcgtatt ttttgatttc ttcaaaagga gcaaattctc ctcttaattc cttagcagac
     3361 gtatgaatag tttgtaatat tggagtaatt ttgtcgaact tggtcttgat tgacgttgaa
     3421 tcaagcgtaa tcgcagattc gatatactca tttactttga taccagcttc aatatcaaaa
     3481 agataatttt ttacatctaa gcctaaatcc tttagtagtt caagattgta cttttcatct
     3541 tgtcgattga taagcttttc tgtcccttta ccaaagaatt taacaatgta ttgcttattt
     3601 gttgttttgg ccaaatagtt ttgattggtc attccaccca gttgttcaac actgaggact
     3661 tcctcttctt gactaagtaa ggaagaaatt ttttctttaa tgattttctc cacaattaac
     3721 ctccagtact tatacttccc acttaaacac tgttttaaag gctgtgttta aatcggttgc
     3781 aaagacacga tgaatatctt taatttctct tacaggttct tctagataaa ggatattttt
     3841 aagacgattg gcaaatttct tgacttccat catttggata gcattttcaa aatcaatgcg
     3901 accagaacga gatgacccaa ccaaaatcaa gcccttttct aaggcatcgc gagtattgag
     3961 attgacttta tattcgctaa ctcccatcat gagaatcgtt ccctgaggac gaatgtagcg
     4021 aatcaagtca ttaatagctg gtccagtacc atcaccacca caacattcaa aagcatggtc
     4081 aaaggccaaa tcttcaggaa tattatccgt aatatagcat tctttggcaa atgagaagag
     4141 ttccaacttt tcccaatgac gaccaataac cacaatctct gcttctggca aagtatagtt
     4201 gataatattg gcaaccacaa aagctaaact tccatctcca ataacggcga tccgctcccg
     4261 cttgctatga gcaagagtca atagacgatt catagcgtgc atgcccacac tgacaaactc
     4321 tgtaatggct gcaaccgtat cttcaatagc atcataagcc accacacgat ctttagggag
     4381 agaaacaaac tctctcataa aaccatcaaa tccactagac aagaaatggg tccctgtcat
     4441 gtagttttca tagaattctt catcactctg cataggagac tgattgggaa tcatgacaac
     4501 tttttgacca acctcgtagg ttccggtcgg gtcagaaatg acggttccac atgactcgtg
     4561 aatcattgcc attggaagct ttttattcaa aatcttggga tcacgttttc cctgatagta
     4621 acgctgatcc gcatgacaga cagccatgta gttgggacgg ataaggatat gattctcttg
     4681 gtcaatagcc tcttcctgat atttgacatt gataaactta ggcttagtta gttgataaat
     4741 ttgattaatc attttactag tctttctcaa tcatactttt tgcaatcttc aaatctgtta
     4801 cggttgtaat cttcagattt gagtattcac ctttggccaa agccacatct tttcctttga
     4861 tcacaaagat tttacatgca tctgtcaaga tttccttctc ttcatcagaa agagatccat
     4921 aaaggtccat gaagtccttg caacggaatg tttgaggtgt ttgtccttga taaaggtgag
     4981 cacgatttgg aatatctgta ataaattgac cattggtact ttcaacgata gtatcaaccg
     5041 cttctaccac tgtgtccact gcgtcatgat tttgggcaag ttggatattg tcctgaatca
     5101 tgcgaagtgt aataaatgga cgaacagaat cgtgggtaac aacgatatcc tctggagtaa
     5161 gcggacgata agcatcaatg gcttcaatga tgttcttaat acttgtattg cggtcagcac
     5221 caccctttgt aatgatgata cgttccttat aaagaggaag atatttatct acaagatctt
     5281 ctgcatgaga aacccagtct ccatgaacac caactacaat tttttcaata cttggctcca
     5341 agacaaattt ttcaattgta tgaatcaaaa taggtcgatc acctagctct aaaaattgtt
     5401 ttggcaagtt actgatcccc atgcgtgtgc cagttccacc ggcaagaatt cctgcataaa
     5461 tcatctattt tctcctttgt cttactaaaa aaacttattc tctctattat accacaatct
     5521 agtcctatca taaaagaaat actggtcctc cccttctaga ataggagaat tatgcagttc
     5581 tattattcaa agaaactagt ccatttctag taatgactag gaattctgta gcaattacta
     5641 ataaatggct gcgaaatttt agagtccttc agaataatat actttcctta aagaaaactt
     5701 aaaacttaag atttgaaact tcaaagtgat tacttgactt actgcccttc atttcttatt
     5761 agctaacttt atgatataat gaaaaacgag gtaaattgaa tgaaaagtat aaaattaaat
     5821 gctctatctt acatgggaat tcgtgtcttg aatattattt ttcccatcct aactggaacc
     5881 tatgtcgcgc gtgtcttgga ccgaactgac tatggttact tcaactcagt cgacactatt
     5941 ttgtcatttt tcttgccctt tgcaacttat ggtgtctata actacggttt aagggctatc
     6001 agtaatgtca aggataacaa aaaagatctt aacagaacct tttctagtct tttttatttg
     6061 tgcatcgctt gtacgatttt gaccactgct gtctatatcc tagcctatcc tctcttcttt
     6121 actgataatc caatcgtcaa aaaggtctac cttgttatgg ggattcaact cattgcccag
     6181 attttttcaa tcgaatgggt caatgaagct ctggaaaatt acagttttct cttttacaaa
     6241 actgccttca tccgtatcct gatgctggtc tctattttct tatttgttaa aaatgaacac
     6301 gatattgttg tctatacact tgtgatgagt ttatcgacgc tgattaacta cctgattagt
     6361 tatttttgga ttaaaagaga catcaaactt gttaaaattc acctaagtga ttttaaacca
     6421 ctctttctcc ctctgacagc catgttagtc tttgccaatg ccaatatgct cttcactttt
     6481 ttagatcgcc tcttcctcgt taaaacaggg attgatgtca acgttagtta ctataccata
     6541 gctcagcgaa ttgtgaccgt tatagctggg gttgtaacag gtgcaattgg agtgagtgtg
     6601 cctcgtctca gttactatct ggggaaagga gacaaagaag cctatgtttc tctggttaat
     6661 agaggtagtc gaatctttaa cttctttatc attccactga gttttggact catggtttta
     6721 ggaccaaatg ccatcctact ttacggtagt gaaaaatata tcggaggcgg catcttgacc
     6781 tctctcttcg cttttcgtac gattatcctg gccttagata ccattcttgg ttcccaaatt
     6841 ctctttacca atggctatga aaaacgtatc acagtctata cagtctttgc tgggctactc
     6901 aatttgggct tgaatagtct cctttttttc aaccatatcg tggctcctga atactactta
     6961 ctgacaacta tgctatcaga gacttctcta cttgttttct atatcatttt catccataga
     7021 aaacaactca tccacttggg acatatcttt agctatactg ttcgatactc tctcttttca
     7081 ctttcctttg tagcaattta tttcctgatt aatttcgtgt atcctgtaga tatggtcatt
     7141 aatttgccat ttttgattaa tactggtttg attgtcttgc tatcagctat ctcttatatt
     7201 agtctacttg tcttcacaaa agatagcatt ttctatgaat ttttaaacca tgtcctagcc
     7261 ttaaaaaata aatttaaaaa atcataggag tttaaaatga aacaactaac cgttgaagat
     7321 gccaaacaaa ttgaattaga aattttggat tatattgata ctctctgtaa aaagcacaat
     7381 atcaactata ttattaacta cggtactctg attggggcgg ttcgacatga gggctttatc
     7441 ccttgggacg acgatattga tctgtccatg cctagagaag actaccaacg atttattaac
     7501 atttttcaaa aggaaaaaag caagtataag ctcctatcct tagaaactga taagaactac
     7561 tttaacaact ttatcaagat aaccgacagt acgactaaaa ttattgatac tcgaaataca
     7621 aaaacctatg agtctggtat ctttatcgat attttcccta tagatcgctt tgatgatcct
     7681 aaggtcattg atacttgtta taaactggaa agcttcaaac tgctgtcttt cagtaaacat
     7741 aaaaatattg tctataagga tagcctttta aaagattgga tacgaacagc cttctggtta
     7801 ctccttcgac cggtttctcc tcgttatttt gcaaataaaa tcgagaaaga aattcaaaaa
     7861 tatagtcgtg aaaatgggca atatatggct tttatccctt caaaatttaa ggaaaaggaa
     7921 gtcttcccaa gtggtacctt tgataaaaca atcgatttac cctttgagaa tttaagcctt
     7981 cctgcacctg aaaaatttga tactattttg acacaatttt atggagatta tatgacccta
     8041 ccaccagaag aaaaacgctt ctacagtcat gaatttcacg cttataaatt ggaggattag
     8101 gatgcaatat ttagaaaaaa aagaaattaa agaaattcaa ctagccctgc tggactatat
     8161 tgatgagact tgtaagaaac atgatattcc ttattttctc agttatggaa ccatgcttgg
     8221 agccatccgc cacaaaggta tgattccttg ggatgatgat attgatattt ccctttatcg
     8281 tgaggattat gagcgtttac tgaagattat tgaagaagaa aatcaccctc gctacaaggt
     8341 tctttcctac gatacatctt cttggtactt ccataatttc gcatcgattt tggacacttc
     8401 tactgttata gaagaccatg ttaagtacaa gcgtcatgat accagccttt tcatcgatgt
     8461 cttcccaatt gatcgattta cagacttgag cattgtcgac aagagctata agtatgtggc
     8521 tcttcgtcaa ctagcttata tcaaaaaatc acgagcagtt cacggtgata gcaaactaaa
     8581 agattttctt agattatgta gctggtacgc tctccgattt gtcaatcctc gctactttta
     8641 caagaaaatt gatcaactag tcaaaaatgc tgtaaccaac actcctcaat atgaaggagg
     8701 agttgggatc ggtaaggaag ggatgaaaga aatcttccca gttgatacct ttaaagaact
     8761 gattttaact gagtttgagg gccgtatgtt gcctgttccc aaaaaatatg accaattttt
     8821 aacccagatg tatggcgatt atatgacacc accatcaaaa gaaatgcaag agtggtatag
     8881 tcatagcatt aaagcttatc gcaaaaactg attgaggggg attatacaaa ctactaagat
     8941 agaggttatt caaaaacata attttagtag aaaatgaaat acatattccc acaataaaac
     9001 gcatcatatc aaggtttttg aaaaaccttg atatgatgcg ttttataatt ttaaagactt
     9061 ttttctatag tagattgaaa taagatgcga acaaatcaat tagaaaattc aaattaattt
     9121 atagaaatat tttagtattc ctgtgtactg ttctaaattc agtctgctat atcttatttt
     9181 tctatttaaa tcgcttctgt aacaaagcta cgactttcaa gtaccttaag catggcatta
     9241 gctgtatcta gcgctgtgaa gaggggcacc ccgtgttcaa tggctgaacg acgaatttgc
     9301 tcaccatctt cgtcagcagt tcgttttgtt cctactgtgt taatgatagc ttgaattctt
     9361 cctttgcgta caaaacttgg gatatcctta tcgtcatcac caatcttacc aacaggttgg
     9421 gcttgcaagc catgactagc aaagaaggct gctgtccctt ctgtcgcaag gattccataa
     9481 ccaatgtttt ggaaacgacg agccaagttc aaggcttctt ctttggcatc atcagcgatg
     9541 gtaaagacga cattaccaaa agttggcaag tgtagataag aagcttcaaa ggctttatag
     9601 agagcttttt ccaaagtagc atcagaaccc ataacttcac ctgttgactt catttcagga
     9661 ccgagcaagc tgtctacctt agctagtttg gtaaaggaga agacaggtgc cttgatatga
     9721 acacgggtgc tttcagggta aagtccattt tggtagccaa gttctgataa actttgacca
     9781 agaatgagtt tggtcgctac ttgagccata ggaatattgg ttaccttaga taggaatgga
     9841 acagtacggc tggcacgtgg attgacctca ataacgtaga ctttttcatc cttgataaca
     9901 aactggatgt tcatcattcc aaggcagtga agaccgattg ctaagcgttt ggtgtagtct
     9961 gcgatggtct cctgaacctt ttgcgacaag gtttgtggtg ggtaaacagc cattgagtca
    10021 cctgagtgga caccagcacg ttcgatatgc tccatgatac caggaatgag tacattttta
    10081 ccatctgaaa tggcatcaac ttcgcactct tgcccaacga tataagagtc gacaagaact
    10141 gggtggtctg gactagcctt aacagcagtt cgcatgtaag aacgaaggtc ttcttcgttt
    10201 tcaacgattt ccatggcacg tccaccaagt acataagatg ggcggacaag aactgggaag
    10261 ccaatcttgc gagctgcaag agctgcttct tcttcattgg tagccgtttg tcctggtggc
    10321 tgtggaatat ccaattcttt gagagcttgc tcgaagaggt cacggtcttc ggcacgatct
    10381 aggtcagcaa cctgtgtacc aaggatggtc acacctgctt ttgccaatgg ctccgcaagg
    10441 ttgatggctg tttgaccacc gaactgaacg ataactccct ttggttgttc caagtcaatg
    10501 acgttcataa catcttcgaa tgtcaatggc tcaaagtaaa gcttatctga tacagagaag
    10561 tctgttgaaa cggtctctgg gtttgagttc atgatgatag cttcataacc agctgcctgg
    10621 atagccttaa cagagtgaac ggttgcgtag tcaaactcaa ccccttgacc gatacggatt
    10681 ggacctgaac ctaggacaag tacagattct ttatcagatc tgatagattc attttcccaa
    10741 ccataggttg aatagaaata tggcgtttcg gagtcgaact ctgccgcaca agtgtctacc
    10801 atcttataaa ctggaacaat cttgttttcc aagcgaagtt ggcgaacttt atcatcagtc
    10861 gttccccaga gttcagcaat cttacggtct gaaaaaccat taagtttggc tgttttcaaa
    10921 acttctaaat cttgtggatg agcacccaat tcttgctcaa tttcaaagat atgcaagagt
    10981 ttatcaagat agaagatatc aatttttgta agctctgcaa tttcttcagg tgtgtagcca
    11041 cgacgaatgg cttctgatac gtagaagaga cggtcatctt gggctttgac aaccttttca
    11101 atcaaggcat catcagaaac tgctgcaagt tcaggtattt cattgtggtg caccccaatt
    11161 tcaagggagc ggcaggcctt gagaagagat tcctcgatgt tacgaccgat tgccatgact
    11221 tctccagtcg ccttcatttg tgtaccgaga cggcgttcac ccttttcaaa cttgtcaaat
    11281 gggaaacgtg gaatcttagc aactacgtag tcaagggctg gttcaaacat ggcataggtt
    11341 gaacctgtaa ctgggtttat aacctcatcc aaggtcaaac ctactgcaat cttggcagcc
    11401 aacttagcaa tcggatatcc tgtcgcttta gaagcaaggg ctgacgaacg tgatacacga
    11461 gggtttactt cgataacata atacttgaag ctgttaggat caagagctag ctgaacatta
    11521 catccacctt caatcttgag ggcacgaata atgctcaagc tcgcatcacg aagcatttgg
    11581 ttttcatagt ctgacatggt ttgcgcaggg gcaaatacaa tggaatcccc tgtgtgaatc
    11641 ccaactgggt caaagttttc catgttacaa acaaccaagg cattgtcagc tgagtcacgc
    11701 atcacttcgt attcaatttc cttgaaaccg gcaatcgaac gctcaatcaa acattgggta
    11761 acaggtgaca atttcaaacc attttcagtg atttcacgca attctttctc gttggcacac
    11821 ataccaccac cagtaccacc aagggtaaag gctggacgaa cgatgactgg gtagccaatt
    11881 gtcgctgcaa aggcaactgc ttcttctact gtgttaacaa tttcagattc tggaatgggt
    11941 tgttcaagct cttccatcaa ttgtttaaag aggtcacggt cctccgcttg gtcaatggca
    12001 gataatttgg tacccagaag ttcaacgcca agctcgtcta ggataccatt tttagataat
    12061 tccatggcca tgttgagacc tgtctgacca ccgagtgttg gtagcaaggc atctggacct
    12121 tccttacgaa gaatacgtgt cacaaactca agtgtaatcg gttcaatgta aaccttgtca
    12181 gcaatttcct tgtccgtcat gatggttgca ggatttgagt taaccaaaac aacctcataa
    12241 ccttcctctt tcaacgacaa gcaagcctga gtcccagcgt agtcaaactc agcagcctga
    12301 ccaataataa tcggaccaga accaatcacc ataatttttt gaatatcagt acgtttaggc
    12361 atatataaga tattaagggt gtcaagcgga caaagctaaa ataggagtta tgacgaagaa
    12421 ctgtcagttc taggaataac tatcttttta gcaccgtccg tagcccgtat tcagttcagc
    12481 aaatacggag cacccttctc ctttctattc gtcgcctctc agggcgacat taaataagat
    12541 acaaaggacg aatagaaagc gattgaattt taggaaatca aggaaggatt gacaatccaa
    12601 gttggtttct ctacattctg agctttccgt ccgtgttcag ttacataaat tctccgacga
    12661 gcttttactc gttcttagtt tgattgttta aaaacttcca tcatctcgat aaactcgtca
    12721 aataggtagc tagcgtcgtg tggcccagga gctgcatctg ggtggtattg aacagagaaa
    12781 gcaggttggt atctgtggcg cacaccttcc actgacttgt cattgatttc ttcgtgggta
    12841 ataatcaagt gctctggcaa atcctcgcgg ctgactgcat aaccatggtt ctggctggtg
    12901 aagtctactc gtcctgttgc gatttcacgt accgcatggt tgaatccacg gtggccaaac
    12961 ttcatcttat aggtcttagc cccgtttgcc attgcaaaga gttggtgtcc catacaaata
    13021 ccaaagattg gaatttttcc ttgtacaccg cgaatcatgt cgagtgcttg tggaacgtct
    13081 tctgggttac ctggaccatt tgacaacata actccgtcag gattgagatg gagaatttct
    13141 tcagccgttg tcgaataagg aacaactgtc acgttacagt tgcgtttaga aagttcacgt
    13201 aggattgagt gcttgagacc aaagtccact agcaccacgc tcaaaccaac tcctggagct
    13261 ggataagacg ttttagtaga aacctgtttg atattgtctg tcggtaaaac tgttgcttgg
    13321 agctggtccg tcacatggtc catactgtcc ccaacatggg tcaaggttgc acgcatagta
    13381 ccatgcttac ggataatctt ggtaagagca cgcgtatcaa ttcctgaaat ccctggaatt
    13441 ttcttggctt tcaaaaattc atccaaggtc atttggttgc gccagttgct agctctacgc
    13501 gcttcttcaa aaacaacgac tcccttacaa gttggaataa tggattcata atcatcacga
    13561 ttaataccat aatttcctac caaaggataa gtaaaggtca agatttgtcc attataagac
    13621 tggtctgtaa tggattcttg gtagccggtc atccctgtat taaagacgat ttcgcctgtt
    13681 acatcaatat ctgctccgaa ggccttgcct tcaaaaactg tgccatcttc taatactaga
    13741 attctttttg tcatattttc acctctcgtg gacgctcact ggcgtctttt aacgtcttgt
    13801 gttttagttg gcgtttctac tcgctagtac ggattctaag attgccattc gaacaaagac
    13861 accattggtc atttgttgga caatccgtga ttttggtgct tcaaccaagt ggtctgctat
    13921 ttctacatca cgattgattg gagctgggtg catgaggatt gctgtttctt tcaaacgatc
    13981 gtaacgttct tgagtcaagc catgttgggc atggtagtct tcttttgaaa atacagctcc
    14041 actatcatgg cgttcgtgtt gcacacggag aaacatcatg acatcaacct gatcaatgat
    14101 ttcatcaatg gttacaaact gtccatagtc tgcaaactct tgacttctcc attcctcagg
    14161 tccagcgaaa aagagttcag ctcccaagcg tttcaaaatc tgcatattgg atttggcaac
    14221 gcgtgagtgg tccaagtcac ctgcaatagc aactttaaga ccctcaaagt ggccaaattc
    14281 ctcataaatg gtcatcaaat caagcaagct ctggctaggg tgttggcccg aaccatctcc
    14341 accattgatg atggaagtcg taatcgttgg actagcaatc aattctctat agtagtcgac
    14401 ctctggatgg cgaatcacac agacatccac tcctaaagca gacagagtca aaatggtgtc
    14461 ataaagtgtc tcacccttat taaccgagct agtcttcaca tcaaagtcaa gtcgttccaa
    14521 tccaagttta atctctgcga cttcaaagga cttatgtgtc cgtgtagaat cctcaaagaa
    14581 gagattggaa acaatcggat ggtcttcata gggaagctgg gctccatttt taaactcaat
    14641 tcctcgcttg atcaatttca ttacttgatc gacagtgagg tcttccatgg acaccacatg
    14701 gttcaatgct tgttgatttt ctgacatggc tactccttta actttctaag cttcttcagt
    14761 aatcagaact ctgtcttggt catcaagttc tgtcatctct acgatgattt cttcagaacg
    14821 actggttggg atattttttc caacgtaatc tggacggatt ggcaattctc tatgtccacg
    14881 atcgactaga actgctaaac tcacacgcgc aggacgacca tgaccgacaa tattatcaat
    14941 agcagcacgg atggtacgac ctgtatagag cacatcatcc accaagataa cttcgcggtc
    15001 tgtcacatcg acagaaacca aagaagtatc ttctccactt ttaacatcat cacggaaagg
    15061 tttagtatcc aattccacaa caggaactga aagattttct aactgcttca aacgttcttg
    15121 gattcggtgg gcaataaaga caccacgagt tttaatacca gccaagacga tcttattcaa
    15181 atctttgttg cgttcgataa tctcataagt aatacgcgta atcgctcgtt tgacggtcaa
    15241 ttcgtctaca acttcttttg ttttcatgac aaacctccaa aaagaaaagt ctccttaaac
    15301 aaggagactt gaaatttata gccaagcgag ccctactgca cacagtatag acttcaccct
    15361 tctactttat cgcgctcctt gcctgcctca cgggacaggt ttaaaggaat atttagttat
    15421 catttactat agcacaaagc atgcttaaaa tcaagcaaaa agtttcaatg tagcatctta
    15481 caaattgcta aaatcatata attgtgggta ctggtcacac tctggatttt ttggatggca
    15541 aatggctctt ccaaaataaa tcatggcctg atgggcagct aaccactgct caggcggcaa
    15601 gatatccatg acccgctttt ccacctcaag tggcgtcgct gattttttga caatatcgtg
    15661 gtgtttgcaa atacgctcca catgagtatc cactgcaaag gctggaattc caaatcctac
    15721 actcatgaca acattggctg tcttgcgacc aacacctgcc aaactctcca attcttcacg
    15781 tgtctgaggg acttgaccat caaaatcgtc tagtaactgt tgggcacatt ttttaaggaa
    15841 tttagcttta ttccgataca atcccaagcg agaaatatgt gaagcaatct cactctctgt
    15901 cgctacagac atagcttggg gtgttggaaa ggcaacaaag agacctggtg tggccttatt
    15961 taccgctgca tctgtcgtct gggctgataa catgaccgca accaggagtt caaaatgatt
    16021 ggtaaaatca agactaggct tggcatctgg gaagagggca atgatttctt ctagcacctt
    16081 tcgtgctcgt ttttttgaca agaccattat tcatctccgt caaatagtcc ttgtaagcca
    16141 gcaaaaggac tgttttcttc tttctttact gctttttgag cttggtattc ttcctctgtc
    16201 atgatttgcc agtcatttcc tgagataaat ccttgaccag cttcttcttc agccgtcaag
    16261 accttgatag gaatgtttag caggatattg tctgatacac tctcagcaag gtcaagctcc
    16321 ccattttcga tgggcaagac caagtcatca tctaaaactt cttgatctag ctggttagtt
    16381 gcgccttcca tgaaaacttc cgtgactgga taagattcaa ctaactcaac tggctccata
    16441 ctgcgactcg aagcaagaac aatggtataa gatagttgat aatctaagaa atacatacgg
    16501 tcttcatatt gtactttccc aactgcaagg atatctttta catctaaaat ttcttgatta
    16561 cgtgcacgca ggtcatcaac taaatctaac gtttgttcaa agttcaaacc ttcagactgc
    16621 ttacgaattt cttgaatatt taatttcata cttcctccat aaagatttac tctcttgatt
    16681 ataccatgaa aaggctacaa atcagcacac caaactttgt aattaaaatt caaaatttta
    16741 acatatttac tatgatagtt ttatttttta gtgctatact atagggaaag agtacatcag
    16801 atcaaggagg atgctcacat ggaagacaag aaactcattc aactcctatc caagttaaat
    16861 aaaagctacc aaaactgtaa acagggtacg gcagatgata ttcgactaca agagctgcta
    16921 aacactacta tgcaagagct caaaaaaacg gaacagttga acaacagtat cttaattgat
    16981 cttgagaaat tttaccaacc taccagtctt ctgattggac tgggtagcct aaaactaaac
    17041 gatcaagcac gcactgcttg gcgaaactat gataaattcc attacgatca tgtcaaacac
    17101 gtactaagtc tctatggacc tgtttttgaa ttttagagca tagaatttcc agttttctgt
    17161 tgacaaaatt tccttaaagg tataatataa agatactaat actcggaggt aagggagaca
    17221 tgaacaacta agtctatcaa ataaagaacc tttatttagt agatcttgtt tttgtctctt
    17281 tttgtgtgct cttttatgct ctttttctgg catgttaata gagttttttt gacatagact
    17341 ttgggctcta ctaggtaaag tagagctttt tgttatgcac tatgaacatt ctagaaaggg
    17401 aaatcatatg ataaaaatca atcatctaac catcacacaa aacaaagatt tacgagatct
    17461 tgtatctgac ctaaccatga ccatccaaga cggggaaaag gttgctatta ttggtgaaga
    17521 aggaaatggc aaatcaacct tacttaaaat tttaatgggg gaagctttgt ctgatttcac
    17581 tatcaaggga aacatccaat ctgactatca gtcactggcc tacattcctc aaaaagtccc
    17641 tgaggaccta aaaaagaaaa ctttacacga ctacttcttt ttagattcta ttgatttaga
    17701 ctacagtatc ctctatcgtt tggcggagga attgcatttt gatagcaatc gtttcgcaag
    17761 tgaccaagag attggcaatc tatcaggggg cgaagctttg aaaattcagc ttatccatga
    17821 gttagccaaa ccctttgaga ttctattttt agatgaacct tcaaatgacc tagaccttga
    17881 gacagttgat tggctaaaag gccagattca aaagaccagg caaaccgtta ttttcatttc
    17941 ccatgatgaa gactttcttt ctgaaacggc agacactatt gttcacttgc gactggtcaa
    18001 acaccgtaaa gaagcggaaa cgctagtaga gcatttagac tatgatagct atagtgagca
    18061 gagaaaggct aattttgcca aacaaagtca gcaagctgct aacaaccaaa gagcctacga
    18121 taaaaccatg gaaaaacatc ggagagttaa gcaaaatgta gaaactgcgc ttcgagctac
    18181 caaagatagt actgccggtc gcctattggc taaaaagatg aaaactgtcc tctcacaaga
    18241 aaaacgctac gaaaaggcag ctcagtccat gactcaaaag ccacttgaag aggaacaaat
    18301 ccaacttttc ttttcagaca tccaaccatt accagcttct aaagtcttag tccaactgga
    18361 aaaagaaaat ttgtccattg acgaccgagt tttggttcaa aaactacaac taactgtccg
    18421 tggccaagaa aaaatcggta ttatcgggcc aaatggtgtt gggaaatcaa ctctgttagc
    18481 caagttacag agacttctga atgataaaag agagatttca cttggtttta tgccacaaga
    18541 ttaccacaaa aaactgcaat tggatttatc cccaatagcc tatctcagta aaactgggga
    18601 aaaagaggaa ctacagaaaa tccaatctca cctagctagt ctcaatttca gttatccaga
    18661 aatgcagcat caaattcgct ccttatctgg cggacaacag ggaaaactcc tgcttttgga
    18721 tttagtcctg cgcaaaccaa actttctcct gctggatgaa cccacacgaa acttttctcc
    18781 cacttctcaa ccccaaatca gaaaactctt tgctacctat ccaggcggtc tcatcactgt
    18841 ttcgcatgac cgtcgtttat taaaagaagt ctgctcgatc atctatcgca tgacagaaca
    18901 cggtttgaag ctagttaatt tagaagattt ataaatttgc aacatagcaa aaatccagag
    18961 acgacctctg gattctttta catctgtttt aaacgttcaa tccgttctga gataggtggg
    19021 tgggtataaa agagtttttg gaacccccca cctttcttag gatcattgat ataaagggca
    19081 ctgctagcat catcgacgtg gcgactcata ggtttgctat tgtccaactt atctagggca
    19141 ttaatcattc cctggggatt gcgagtcagc tcgacactag atgcatctgc cagaaattcc
    19201 ctctgacgag aaatagcgag ctgaaccaag gttgcagcga gaggtgccag tacaatagct
    19261 agtagggaaa ccactagcat aatgatttca agaccatttc catctcggtc atcatcactt
    19321 cgtctgcgac ctgctccacc ccaccacatc atacgacctg ccatactaga aagcatggtg
    19381 atagcactag caagggcaac tgcaatagtc gaaatacgga tatcataatt acgaatatga
    19441 ctgacttcat gtcccataac agcttctagt tcttcacgat tcatgatagc tagtagacct
    19501 gaagtcgcag caacagccgc attttgagga ttagaacctg tcgcaaaggc atttaaggct
    19561 ggatcatcaa tgatgaaaac acggggcata ggaatctgag cgaccagagc catatcttcc
    19621 actacatggt agaggtctgg tgccgtttgc tcatccacct cacgcgctcc attcatggac
    19681 atgacaatct ctgtcgattg aaaaatcata gacaaagcgt agataaagcc gataatcagt
    19741 gcaataacca aaccaccaag tccagatctt ataaagagat aaccaaccgc ataaccaaca
    19801 agagctaaga gtaggaaaaa taccagcaac aaaatccagg tttttcgttt attgcttgca
    19861 atttgatcaa acaacatctt agtcacctaa accgctaaaa tcaactttag gaaccgactt
    19921 ttcctcttca ggtgtttgaa ggaaatctgc cgctttaaat ccaaacattc cagcgataat
    19981 attgctcggg aaagtttcta attttacatt gtagttgctg acaacactgt tatagagttg
    20041 acgagagtaa gaaattttat tttctgtgtt tgtcaactcc tcttgcaatt taacaaagtt
    20101 agcactagct ttcaaatctg gatagctttc tgcaactgca aaaatacctg aaacttgacg
    20161 agtgagggca tcactggctt tcatagcttc tgctggtgaa gtcgctgccg ccacttggtt
    20221 acgtagttct gccacctttt caagggtaga accttcatat ttggcataac cttttacagt
    20281 ctcaatcaag tttggcaaga ggtcatttcg acgtttcaac tgaacatcaa tctgactcca
    20341 agcctccttg gtttgcatac gatttttaac caaaccgtta tagctaacaa tcacaaaaat
    20401 aacaataaga gcgataactc caagaataat ccaagtcatg atataagtcc tttctacttt
    20461 tagattagta ccagtatatc aaatttttaa tgattgtggt aaaataagat gatactaaag
    20521 aaggaaataa ctatgaaacc agaaacattt tacaacttgc ttgccgagca gaatcttcca
    20581 ctttcggacc agcaaaaaga acaatttgaa cgttattttg agctcttggt cgagtggaat
    20641 gagaagatta atttgacggc gattacggac aaggaagaag tttatctcaa acatttttac
    20701 gattcgattg cacccattct tcaaggtttg attcccaatg aaactatcaa acttcttgat
    20761 atcggggctg gggcaggatt tcctagtcta ccaatgaaaa ttctctatcc ggagttagat
    20821 gtgaccatta ttgattcact caataagcgc atcaacttcc tacaactctt ggctcaagaa
    20881 ctggatttga acggagttca tttctaccac ggacgtgccg aagattttgc ccaagacaag
    20941 aacttccgtg ctcaatatga ttttgtaaca gctcgtgcgg ttgcccgtat gcaggtccta
    21001 tctgaattga ctattcccta ccttaaggtt ggtggaaaac tattggcact caaggccagc
    21061 aatgcgcctg aggagttgtt agaagctaag aatgccctca atctcctttt tagtaaagtc
    21121 gaagacaatc tcagctacgc cctaccaaat agagatccgc gttacatcac agtggtagaa
    21181 aagaaaaaag aaacaccaaa taaatatcca cgtaaggctg gtatgccaaa taaacgcccg
    21241 ctttaaattt ttaagtaaaa aaatatttac aaaatcaacc tcgctctctt atttttaggc
    21301 tcgggaaaaa atgatttaca aaatcatttt tttctgctat actatcctaa gcaaaggttt
    21361 ttaatgtcat cccgtgaggt gacgaagacg cagaaatatt tgaaactctt taaagtctag
    21421 attttagaga agtcttactc tgagggccta ttgctgtaaa ataatgggct cttttctgat
    21481 gcccaaaagt gaggtttata tgaaacaaga atcaactgtt gatttgttac tagacgttga
    21541 ccaacgtcct tcggatggaa aaggaattct ccttagtttc caacacgttt tcgccatgtt
    21601 tggtgcgacc atcttggtac cattgatttt gggaatgcct gtatctgttg ccctttttgc
    21661 ttcaggtgtt ggaacactca tctacatgat tgctactggt tttaaagttc cagtttatct
    21721 aggttcttca tttgccttta tcacagctat gtcactggct atgaaagaaa tgggggggga
    21781 tgtatctgct gcccaaacag gggttatctt gactggtttg gtctatgtcc ttgttgctac
    21841 cagcatccga tttgtaggaa caaaatggat tgataaactc ttgccaccaa tcattatcgg
    21901 tcctatgatc atcgttatcg gtcttggact tgcaggttca gctgttacca atgcaggtct
    21961 tgtagcagac ggaaattgga aaaatgctct ggtagccgtt gttactttcc taattgctgc
    22021 ctttatcaat acaaaaggaa aaggcttcct acgaatcatt ccattcctct ttgccattat
    22081 cggtggttac cttttcgcac taactcttgg cttggttgac tttacacctg tcctagaagc
    22141 taactggttt gaaattcctg gtttctactt gccatttagc acaggtggtg cctttaaaga
    22201 gtacaatctt tactttggtc cagaagccat cgctatcttg ccaatcgcta tcgtaacaat
    22261 ttctgaacat atcggagacc atactgtttt gggtcaaatc tgtggtcgtc aattcttaaa
    22321 agaaccaggt cttcaccgta ctcttcttgg tgacggtatc gcaacttctg tttctgcctt
    22381 ccttggtgga ccagccaata caacttacgg agaaaataca ggggttatcg gtatgactcg
    22441 tatcgcttct gtctcagtta tccgtaacgc tgccttcatc gcgattgccc tcagcttcct
    22501 tggtaaattc actgccttga tttcaactat tccaaacgct gtacttggtg gtatgtcaat
    22561 ccttctctat ggggttatcg ccagcaatgg tttgaaagtc ttgattaaag aacgtgttga
    22621 tttcgctcaa atgcgaaacc tcatcatcgc aagtgctatg ttggttcttg gacttggagg
    22681 agctatcctt aaacttggtc cagttacact ttcaggtact gccctttcag ccatgacagg
    22741 aatcatcttg aacttgatct tgccatacga aaataaagac taagagtcta aatacaccta
    22801 atccactcag acagctgagt ggatttttcg tataccataa taaaagtgtc ttaacaaaat
    22861 tattaaaatc aaaaaacgta taatatcaga tattctaaaa ccttgatact gtacgtttta
    22921 tcatagaaat ttttacttta ttttctcatc aaatgagatt tgcatcaatc tcttgtctta
    22981 cttgcgtttc ttcttcgctt tcttcatttt gttagccata cgtttcatgg actgtttcat
    23041 ggcaaattca ccaattttac ctttcaaacc gccaccaaac atctggctca tatctggcat
    23101 tcctgctcct ccgagagctg ataagtcagg cataccgcct tgtcccatca ttccttcaag
    23161 ggcagacata tccattcctc ccatatttgg catattttta ggaaggttat ttggattaat
    23221 ccccatttgc ttcatcattt tattcatatc cccagacata acaccctgca tgagctgttt
    23281 agcctggtta aagtccttga tgaatttatt gacttcgacg aatgtatttc cagaaccagc
    23341 agcaatacga cggcgacggc ttggatttaa caaatctggg ttttcacgtt cttcaggtgt
    23401 catcgaagac acaatcgcac gtttacgagc aatctggcgt tcatccacct tcatgttttg
    23461 aagtgctgga ttgttggcca tacctggaat catcttgagc aagtcttcca tcggccccat
    23521 attttgcacc tgatctaatt gatcgatgaa aacattaaaa tcaaaggtgt tttcgcgcat
    23581 cttctcagcc atttcaaggg ctttttgttc atcgtattcc tgagaagctt tctcaatcaa
    23641 agtgagcata tcccccatgc caaggatacg gctagacatg cggtctgggt ggaaggtttc
    23701 aatgtccgta atcttttcac ctgtaccagt gaacttgatt ggttttccag taatgtgaca
    23761 aacagacaga gcagcaccac cacgagtatc gccatcaatc ttggtaagga tgaccccagt
    23821 cacttccaac tgagcattaa actcacgcgc aacattggct gcttcctgac caatcatagc
    23881 atcaacgaca agcaagattt catttggttg agccaatgct ttcacatcac gaagctcatt
    23941 catgaggagc tcatcaatct gcaaacgacc cgcagtatca atcaagacat agtcgttatg
    24001 attagtttga gcttgctcca aaccttgacg tacaatctca acagctggaa cctctgtccc
    24061 aagagcgaaa accggcacat caatctgttg tcccagtgtc ttcagctgat caatggcagc
    24121 aggacggtaa atatccgccg caatcatcaa aggacgggca ttttcttcct tcttgagttt
    24181 gttagccagc ttacctgcaa aagttgtttt accagctccc tgcaaaccaa ccatcatgat
    24241 gatggttgga atcttaggtg acttgataat ttctgccgta tcagaaccta aaacggctgt
    24301 cagttcctca tcaacgattt taataatctg ttgcgcagga ttaagtgtat caatgacctc
    24361 atgcccgact gcacgctcgc gaactttctt gataaagtcc tttacaacag gcaaggcaac
    24421 gtcggcctcg agcaaggcca agcgaatttc tttggttgcc tcttggacat cagattcaga
    24481 gatttttcct tttttacgta gatttttaaa gacgttctgc aaacgttctg ttaaactttc
    24541 aaatgccatt tttcttcctc ttattctcta ttatcaatgc ttgttaaaat ttctatctgc
    24601 tcctgcagaa agtcatcctt gggatagcgc tccaaaatct gatcaaaaat ctgactgcgg
    24661 acaatatagt ccgagtacat gtgcaatttc atctcataat cttccagaat cttttctgtt
    24721 cgcttgatat tgtcatagac agcctgacga ctgacaccaa actcctcggc aatttcagca
    24781 aggctgtaat catcagcgta gtagagctcg atataattca tttgcttatc tgtcaaaagc
    24841 gccgcataaa attcaaagag cgcattcata cgattggttt tttcgatttc cataactttt
    24901 attataccaa aaattagcct aatctaccac actaggaagc cgatccaaga agatagatag
    24961 ctaaatttga aaaagacatg agcctagccc caagtaattt ccaattgata gctggcaaaa
    25021 ggatgtccct cttgattttg tagttgataa tctagttcaa tcttttgcct atcaacttga
    25081 taatggctcg tttggatgat aaactcctgc atgcccatag gtgtaggaat ataggctaaa
    25141 ctatcgctat cctttagaaa gcgcataatg gtcttgggat tagaaaatcg gctcatcaca
    25201 agttcttgac catgaaattt aatcactact ttttcctttt cctcattata gaaaagcagg
    25261 tagctataat ctcctttttc atgcacttcc acatcataaa gccggtcaat cacttccaac
    25321 tgctcatcaa actgaattgt atttcgcatc cgaatcttca catcaggccc tctttcttgt
    25381 ctcttgtcct actattttac caaaaagagc aggattttgc tataatggtc atatgaacga
    25441 aaaagtattc cgtgacccag ttcacaacta catccatgtc aataatcaaa ttatctatga
    25501 cttgattaat acaaaagaat ttcagcgttt gcgccgtatc aagcaactgg gaacctccag
    25561 ttataccttc cacggtggag agcacagccg cttctctcac tgtctaggag tctatgaaat
    25621 tgcacgacgc atcacagaga ttttcgaaga aaaatatcct gaggaatgga atcctgccga
    25681 gtctctcttg accatgaccg ctgctctcct acacgacctt gggcatggtg cctactccca
    25741 tacttttgaa aatctctttg atacagacca tgaagccatt actcaggaga ttattcaaaa
    25801 tcctgagaca gagattcacc aagtcctgct acaagtggca cctgatttcc cagaaaaggt
    25861 ggccagtgtc attgaccata cctatcctaa taagcaggtc gtgcagctca tttctagcca
    25921 gattgatgcg gaccgcatgg actatctctt gcgtgactcc tattttacag gagcatccta
    25981 tggggaattt gacctgactc gaatcctccg agtcattcgt cctatcgaaa atggtatcgc
    26041 ctttcagcgc aatggcatgc acgccatcga agactacgtc ctcagtcgct accagatgta
    26101 catgcaggtt tatttccacc ccgcaacacg cgccatggaa gttctcctac agaatcttct
    26161 caaacgcgcc aaggaactct atcctgaaga caaggacttc tttgcacgaa cttctccaca
    26221 cctcctgcct ttctttgaaa aaaatgtgac cttgactgac tatctggctc tagatgatgg
    26281 tgtgatgaat acctactttc aactctggat gaccagtcct gacaagattc tcgcagactt
    26341 gtcacaacgc tttgtcaacc gcaaggtctt taaatccatt accttttcac aagaggacca
    26401 agaccaactc gccagcatga gaaaattagc tgaggatatc ggctttgatc ccgactacta
    26461 cactgccatt cataagaact ttgacctccc ttatgatatc tatcgtcccg aatctgaaaa
    26521 cccacggaca cagattgaga ttttacaaaa aaatggagaa ctggccgaac tctctagcct
    26581 gtctcttatc gtccaatccc ttgctggcag tcgccacgga gataatcgtt tctatttccc
    26641 taaagaaatg ttagaccaaa acagcatctt cgcaagcatt acccagcaat ttttacactt
    26701 gattgagaac gatcatttta ccccaaataa aaactagaag aggaaattta tgagtattaa
    26761 actaattgcc gtcgatattg acggaaccct agtcaacagc caaaaggaaa tcactcctga
    26821 agtcttttct gccatccaag atgccaaaga agctggtgtc aaagtcgtga ttgcaactgg
    26881 ccgccccatc gcaggtgttg ccaaacttct ggacgacttg cagttgagag accaaggtga
    26941 ctatgtggtg accttcaatg gtgcccttgt ccaagaaact gctactggcc atgagattat
    27001 cagcgaatcc ttgacctatg aggattatct ggatatggaa ttcctcagtc gcaagctcgg
    27061 tgtccacatg catgccatta ccaaggacgg tatctatact gcaaatcgca atatcggaaa
    27121 atacactgta cacgaatcaa ccctcgtcag catgcctatc ttctaccgta cccctgaaga
    27181 aatggctggc aaagaaattg ttaaatgtat gtttatcgat gaaccagaaa ttctcgatgc
    27241 tgcgattgaa aaaattccag cagaatttta cgagcgctac tccatcaaca aatctgctcc
    27301 tttctacctc gaactcctta caaagaatgt agacaagggt tcagccatta ctcacttggc
    27361 tgaaaaactc ggattgacca aagatgaaac catggcaatc ggtgacgaag aaaatgaccg
    27421 tgccatgctg gaagtcgttg gaaaccccgt tgtcatggaa aatggaaatc cagaaatcaa
    27481 aaaaatcgcc aaatacatca ctaaaacaaa tgacgaatcc ggcgttgccc acgccatccg
    27541 aacatgggta ctgtaaaagt atcatttttc aataagaatt gattagcaat aaaatccaat
    27601 gaattttttt agcaaactat ttaatttaaa acaaaataat cataatagag acacaaattc
    27661 tgattgtaac aatttttacc taaacgaatt agaatgtggc cttactcctg ggcaactcat
    27721 actcatagat tggactcaaa aaacagggag aaattataat ttcccaagat attttaaata
    27781 ctctcttcaa attgaccctg aatctacaca caatcaatta tacaaattag gatacttcac
    27841 taaaaataag actttatcat atcttacagt agtagaatta aaaactatat tatctaaaca
    27901 taatttagct acttctggaa aaaaagcaga attaattaca agaataatta ataatgttaa
    27961 cattgacaat ttagatattc cgttcgaatt taaactaaca aaagaagcac aaaatcttat
    28021 tatcgaacat agtgactata tcaaagcata ctatgataaa gacataacta tggaagatta
    28081 ttgtaaagaa aaaaacaata tctcttttaa agcaactttt ggtgatataa aatggagtct
    28141 cttaaataaa caagctcata ggaatactgt atcaggagat tttggatgct tatctaacac
    28201 acgaaaggct cagggaagac atttggaaca agaaggtaat attaaacatg ctttaatata
    28261 ttacatagaa tctttgataa ttactatttc aggattagaa aacaattttt cagccactga
    28321 ttatccagta tattatcccg attcgatacc tgactactca ctaaaacata ttcaaacatt
    28381 aatggaatca ttatctgatg acgattatga ttttgctttt gatgaagcat tatttcgctt
    28441 ctcaattttg aatgcaaatc attttttatc taaggaagat attgactatt taagagttaa
    28501 tttacctcgt tccactgctg aagaaataaa caattactta aagaaatatg aatgttatag
    28561 tcctttaaat aatttagaac ttgacgattt tgaataaatt gactatacaa acatttatat
    28621 actcgatata gtctcaattt tatctgatga ttgcccaaat ttttcaataa taaaacgcat
    28681 aatattatgg agacaatccc ctatattatg cgttctttta atatcaaaga ctttttgaca
    28741 aacttctttg atatctaatt acatgccccc tgcaggaatc gaacctgcaa ctactcctta
    28801 ggagggagtt gttatatcca ttgaactaag ggagctagat aaaaactctg ctgaaaagca
    28861 gagtttttta gtcgaattaa cgacggattt ctttgatacg agctgcctta ccttgaagag
    28921 cacgcaagta gtacaatttc gcacgacgta ctttaccgta acgaacaact tcgatttttt
    28981 caacacgtgg agtgtggatt gggaagatac gctcaacacc tacaccgtta gagattttac
    29041 gaactgtgta gttttctgag attccagcac ctttacgtgc gataacaaca ccttcaaaaa
    29101 tctggatacg ttcacggtta ccttcgacaa ctttcgcgtg tacacgaaca gtgtcaccag
    29161 gacggaatga tgggatatct gtacgaagtt gaccttcagt caagctttgg attaatggat
    29221 tcattttatt ctcctatctt tgtcaatctt gaggaaactt cctcagcgga taaactgtat
    29281 tcttgtgcgt ccattacaca caagatacag tttaccaaat tttcacaaaa aagtaaagaa
    29341 atttatagca aaattcctaa aaaaatcgca accaaaccac ctatgtaagt caaagtcagg
    29401 taagaataaa agaccttctt atcacttagc agtctttgaa gttcgtcatt caaggtcgaa
    29461 aaagttgtta aaccgccaca aaatcctgtt gctagaatag catatacttc cttagactct
    29521 acatgattgt agaatactcc aattaaaaaa caacctaaaa gattagctat gagcgttccg
    29581 agtggcaatt tagaagcttg attatagcga gaaaagaaat accgtacgag tgctcccaag
    29641 ccacaggcga ttgcaagata gacgattacc atttcttcct ccccaaatag taagctaaaa
    29701 gcaggcctcc accgatactc aaaagcaaat acagtatcaa actaagataa cgccctgtat
    29761 caagcagctt cacagtatca agcattaggc tggaaaaagt tgttaaacct ccgcaaaaac
    29821 ccgtccccag tgctaaaatc aagcccttac tagtcccctt atagaccaga tagcccttga
    29881 caagataaat caagcagaaa attcccagat agttgacaaa gagagtgccc caagggaaat
    29941 ctggactggc tggtaaccaa gtggaaacta ggtagcggac aagtccgccc aacatagcag
    30001 ctagaaaaat ccctagcgga taaaattgtt cttttttcat ttgatatttt gatcctgata
    30061 atcacgcgaa cgtttgagta tgtccgaaaa agtcgcgaca atagtctcct gatagcgctt
    30121 gtcctctaca cgacttctaa ccttttcaaa aataactgct tctctcttag tatctaaaat
    30181 cggtttccct gaagccttct tataagcgac aactccttca actaagtgca ttcgttcttc
    30241 taacagtttg acaatttggt cgtcgatttg atcgatttct tgacgaataa tatctaaatc
    30301 catacagtct cctcctttat ttgaattatt gtatcaaaaa gccatcaatt aggctagtaa
    30361 aatcccaact ctcgataaga aaaatgcact gattgattac atcagcgcac ttttatgctt
    30421 atcctacttt agcagccaat tcttctgcga attgttccaa gcgttcaata tcttcttcct
    30481 cggcagaaag atcaacttta acacactctg aacctttttc tgctcctgtt gacacaaaga
    30541 cacggtcaaa gtcatcaaca gccttacaaa attcatcgta gaaggtatct cctgagccga
    30601 ccactccgta gattttgcca ttcaagttga gatctgctag gtcttcgtag aagtccatca
    30661 tctcatctgg caattcacca tcaccataag tataggtcgc aacgatagcg atgtctgctt
    30721 ccaagaagtc tgaagcgtca acagttgtac attcatcaac atcaacatcc aagcccaagt
    30781 cacgtaattt gtctgctaca atatctgcaa tttcttcggt attaccggtc atactggcaa
    30841 atacaatttt tgctaatgcc atatcgtcct cctcaattta tctttctcca ttatatcaca
    30901 tctttttcat tttaaaaata aaaattcttg tgctacaatg aaatgagaaa gaattgaggt
    30961 tatttatgga gatttgccaa caaattttag aaaaaattaa agaatacgac accattatca
    31021 ttcatcgtca tatgaaacca gaccctgatg ccttgggaag tcaggtggga ttgaaagcct
    31081 tgctagaaca tcatttccca gaaaaaacca tcaaagccgt cggttttgat gaaccaactc
    31141 ttacttggat ggctgagatg gatcttgttg aagatagagc ctaccaaggc gcacttgtca
    31201 tcgtctgtga tacagctaat actgctcgta tcgatgataa gcgctatagt caaggtgatt
    31261 ttctcattaa gattgaccac catccaaatg atgatgtata cggtgacctg tcttgggtcg
    31321 atactagttc aagtagcgct agcgagatga ttaccctatt tgcccaaaca acccaactag
    31381 ccttggcaga tcgcgatgct gagttgctct ttgcaggaat tgtcggtgat acaggtcgct
    31441 tcctctaccc ttctaccact gcacggactc ttcgcctggc tgcttatttg agagaacata
    31501 actttgactt tgcggctctc actcgcaaaa tggacactat gagctacaaa attgctaaac
    31561 tgcaaggcta catctacgac catctggaag tggatgaaaa tggtgctgct cgcgttatcc
    31621 tgagtcagaa aatcttgaaa caatacaata taaccgatgc tgaaactgcg gccattgtag
    31681 gtgcacctgg acgcattgac agagtgagtc tctggggaat ttttgtcgaa caggctgatg
    31741 gccactaccg agttcgctta cgcagtaaag tccatcctat caatgaaatt gccaaggagc
    31801 atgatggtgg aggccaccct ctagcaagtg gtgctaattc ctatagccta gaagaaaacg
    31861 aaatcatcta ccaaaagtta aaaaacttgc ttaaaaactg ataaaatact tgccaaactt
    31921 ttcagaatct gatagactag tatagtaaca atctatggct cgcaaagaga ccatggcaga
    31981 aaggaaatat tgcaaaatga aaaaagatat ccatccagaa tatcgcccag ttgtcttcat
    32041 ggacacaact actggttacc aattccttag cggttcaaca aaacgctcta acgaaacagt
    32101 tgagttcgaa ggcgaaactt acccattgat ccgtgtggaa atttcatcag actcacaccc
    32161 attctacact ggacgtcaaa agttcactca agcagatgga cgcgtggatc gtttcaacaa
    32221 aaaatacggt ctcaaataat gataagagaa cagttttggc tgttcttttt tgtttcttga
    32281 aatcaactgc tgttttcatg ttccagactc atctgtaggt tcgatttcca tgctactagg
    32341 caggaaggaa atagctgttt caacacgtcc ataatgagct atactattgt cacgaaccac
    32401 actttcattg atggtccaag tggaattcat tttcttaaaa gcttctcgga ctttttccaa
    32461 atctttggag gcaatggcct gctctaaggt ttcaaaacga ggacttatac tcatctgctt
    32521 tcaaaaagca ttctagtcca tctccgatta ccgatggact ttatcacctc cttctccagt
    32581 ccttgtatga catcttgaag ttgattcatg acatcttcca aagttcgaaa ggctttattc
    32641 ttaaatccac gtttacgaat ctctttccac acttgttcaa tgggttcatc tctggtgtgt
    32701 atggaggaat aaaggtaaaa tcaatattag tcggaatatt taaggtactt gatttatgcc
    32761 atatagcatt gtccataacg agtaaaagga taagcttgtg aaagctcttc taaaaaggcg
    32821 ttcatccaca ctccttttta taaacctgaa ataaggcatc aattgtaaca aattctcctg
    32881 cctctgtagc cttcaaatga cgggcaagaa aggctttctc ttcctcaact gtcatatatg
    32941 catggttacg accaccacgt gtttcttgaa ggagagagtc gagtccgaac tcctcatatt
    33001 tttttacgtt tcgccaaatc gttgtttgat tacagtctaa aagct
//
LOCUS       DBEROT010000025        32114 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.25, whole genome shotgun sequence.
ACCESSION   DBEROT010000025 DBEROT010000000
VERSION     DBEROT010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32114
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.25"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..1080
                     /gene="ald"
                     /locus_tag="ACL8CG_001294"
                     /pseudo
     CDS             1..1080
                     /gene="ald"
                     /locus_tag="ACL8CG_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(1381..1707)
                     /locus_tag="ACL8CG_001295"
                     /pseudo
     CDS             complement(1381..1707)
                     /locus_tag="ACL8CG_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(1710..2210)
                     /locus_tag="ACL8CG_001296"
     CDS             complement(1710..2210)
                     /locus_tag="ACL8CG_001296"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343887.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(2403..3371)
                     /locus_tag="ACL8CG_001297"
     CDS             complement(2403..3371)
                     /locus_tag="ACL8CG_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGS1343888.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(3457..3672)
                     /locus_tag="ACL8CG_001298"
     CDS             complement(3457..3672)
                     /locus_tag="ACL8CG_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGS1343889.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDAIWQEYLEH"
     gene            complement(3681..4535)
                     /gene="cvfB"
                     /locus_tag="ACL8CG_001299"
     CDS             complement(3681..4535)
                     /gene="cvfB"
                     /locus_tag="ACL8CG_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGS1343890.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(4595..5152)
                     /gene="frr"
                     /locus_tag="ACL8CG_001300"
     CDS             complement(4595..5152)
                     /gene="frr"
                     /locus_tag="ACL8CG_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGS1343891.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKREKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(5161..5898)
                     /gene="pyrH"
                     /locus_tag="ACL8CG_001301"
     CDS             complement(5161..5898)
                     /gene="pyrH"
                     /locus_tag="ACL8CG_001301"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGS1343892.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(5982..7316)
                     /gene="trmFO"
                     /locus_tag="ACL8CG_001302"
     CDS             complement(5982..7316)
                     /gene="trmFO"
                     /locus_tag="ACL8CG_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGS1343893.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(7561..7728)
                     /locus_tag="ACL8CG_001303"
     CDS             complement(7561..7728)
                     /locus_tag="ACL8CG_001303"
                     /inference="COORDINATES: protein motif:HMM:NF036719.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS1343894.1"
                     /translation="MSVVLFFQVKIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVP
                     IDPLCGKDFIE"
     gene            7811..8615
                     /locus_tag="ACL8CG_001304"
     CDS             join(7811..8179,8181..8615)
                     /locus_tag="ACL8CG_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HGS1343895.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLHYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATKVKINRPKKELANDSGKKKCHAMKSQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLIAEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(8604..9251)
                     /locus_tag="ACL8CG_001305"
     CDS             complement(8604..9251)
                     /locus_tag="ACL8CG_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGS1343896.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(9360..9878)
                     /locus_tag="ACL8CG_001306"
     CDS             complement(9360..9878)
                     /locus_tag="ACL8CG_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGS1343897.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(9915..10043)
                     /locus_tag="ACL8CG_001307"
                     /pseudo
     CDS             complement(9915..10043)
                     /locus_tag="ACL8CG_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(10105..10974)
                     /gene="rsmI"
                     /locus_tag="ACL8CG_001308"
     CDS             complement(10105..10974)
                     /gene="rsmI"
                     /locus_tag="ACL8CG_001308"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGS1343898.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(10977..11294)
                     /gene="yabA"
                     /locus_tag="ACL8CG_001309"
     CDS             complement(10977..11294)
                     /gene="yabA"
                     /locus_tag="ACL8CG_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGS1343899.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(11334..12224)
                     /locus_tag="ACL8CG_001310"
     CDS             complement(11334..12224)
                     /locus_tag="ACL8CG_001310"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGS1343900.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLTKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(12221..12859)
                     /gene="tmk"
                     /locus_tag="ACL8CG_001311"
     CDS             complement(12221..12859)
                     /gene="tmk"
                     /locus_tag="ACL8CG_001311"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGS1343901.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(13081..13878)
                     /gene="proC"
                     /locus_tag="ACL8CG_001312"
     CDS             complement(13081..13878)
                     /gene="proC"
                     /locus_tag="ACL8CG_001312"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGS1343902.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(13882..15144)
                     /locus_tag="ACL8CG_001313"
     CDS             complement(13882..15144)
                     /locus_tag="ACL8CG_001313"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGS1343903.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(15154..16263)
                     /gene="proB"
                     /locus_tag="ACL8CG_001314"
     CDS             complement(15154..16263)
                     /gene="proB"
                     /locus_tag="ACL8CG_001314"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGS1343904.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(16364..18247)
                     /gene="cbpE"
                     /locus_tag="ACL8CG_001315"
                     /gene_synonym="pce"
     CDS             complement(16364..18247)
                     /gene="cbpE"
                     /locus_tag="ACL8CG_001315"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGS1343905.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWRQGINTTYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(18250..19137)
                     /locus_tag="ACL8CG_001316"
     CDS             complement(18250..19137)
                     /locus_tag="ACL8CG_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1343906.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(19127..19588)
                     /gene="lspA"
                     /locus_tag="ACL8CG_001317"
     CDS             complement(19127..19588)
                     /gene="lspA"
                     /locus_tag="ACL8CG_001317"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGS1343907.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(19585..20493)
                     /locus_tag="ACL8CG_001318"
     CDS             complement(19585..20493)
                     /locus_tag="ACL8CG_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS1343908.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKDELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            20522..20683
                     /locus_tag="ACL8CG_001319"
     CDS             20522..20683
                     /locus_tag="ACL8CG_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS1343909.1"
                     /translation="MIPYFRSFPKRKKEHPILLNYLHYLPFSSQPYFQNQFKKITGYT
                     PLQYRKEKR"
     gene            complement(20735..21406)
                     /locus_tag="ACL8CG_001320"
     CDS             complement(20735..21406)
                     /locus_tag="ACL8CG_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1343910.1"
                     /translation="MKKRAIQILLVLSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(21460..21681)
                     /locus_tag="ACL8CG_001321"
     CDS             complement(21460..21681)
                     /locus_tag="ACL8CG_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGS1343911.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLL
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            21953..22762
                     /locus_tag="ACL8CG_001322"
     CDS             21953..22762
                     /locus_tag="ACL8CG_001322"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1343912.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(22943..23818)
                     /gene="aguB"
                     /locus_tag="ACL8CG_001323"
     CDS             complement(22943..23818)
                     /gene="aguB"
                     /locus_tag="ACL8CG_001323"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGS1343913.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(23828..24913)
                     /gene="aguA"
                     /locus_tag="ACL8CG_001324"
     CDS             complement(23828..24913)
                     /gene="aguA"
                     /locus_tag="ACL8CG_001324"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGS1343914.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(24910..26037)
                     /gene="nspC"
                     /locus_tag="ACL8CG_001325"
     CDS             complement(24910..26037)
                     /gene="nspC"
                     /locus_tag="ACL8CG_001325"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGS1343915.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKEVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(26037..27296)
                     /locus_tag="ACL8CG_001326"
     CDS             complement(26037..27296)
                     /locus_tag="ACL8CG_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGS1343916.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(27293..28153)
                     /gene="speE"
                     /locus_tag="ACL8CG_001327"
     CDS             complement(27293..28153)
                     /gene="speE"
                     /locus_tag="ACL8CG_001327"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGS1343917.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            28409..29012
                     /locus_tag="ACL8CG_001328"
                     /pseudo
     CDS             28409..29012
                     /locus_tag="ACL8CG_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846390.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            28992..29117
                     /locus_tag="ACL8CG_001329"
                     /pseudo
     CDS             28992..29117
                     /locus_tag="ACL8CG_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(29089..30564)
                     /locus_tag="ACL8CG_001330"
     CDS             complement(29089..30564)
                     /locus_tag="ACL8CG_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGS1343918.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            31271..>32114
                     /locus_tag="ACL8CG_001331"
     CDS             31271..>32114
                     /locus_tag="ACL8CG_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS1343919.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKG"
BASE COUNT         9341 a         7296 c         5909 g         9568 t
ORIGIN      
        1 taacgaaaac cgtgtcgccc tcacacctgc aggtgttcat agcttagtta gtcgtggtca
       61 tcgtgtcctt atcgaaacaa atgctggtct cggttctggc tttactgatg ctgactatca
      121 aaagcaagga gctgagattg tcgctactgc tggtgaagct tgggcagcag agttggttgt
      181 gaaagtaaaa gaacctttaa gttctgaata cggttacttg cgcgacgatc ttcttctctt
      241 cacctacttg cacatggccg ctgctccaga attagcagat gctatgttag cagcaaaaac
      301 aacaggaatt gcctatgaaa ctgttcgtga caatcaagga caactaccgc tcctcgttcc
      361 tatgagtgag gttgcaggtc gtatggctgt ttaaatcgga gctcacttcc ttactaagca
      421 agctggtggc tctggtgttc tacttggtgg tgtaccaggt gttccaaaag gaaaagtaac
      481 tatcatcggt gatggtgtcg tcggtacaca tgctgcccgc atcgcccttg gtcttggtgc
      541 tcaagtgact attttagata ttagtgccaa gcgtctctca gttctagaag aagtctttgg
      601 aagtcaaatt caaactctta tgtctaattc attcaacatt gaagcaagtg tgagagatgc
      661 tgatgtggtg attggagcca ttctcatccc tggtgcaaaa gcaccggaat tggtgacaga
      721 tgagatggtc aaacaaatgc gtccaggctc tgtatcgttg acattgctgt tgaccaaggt
      781 ggccttatcg aaacagctga ccgtgtgaca acgcacgatg aacccgtcta tgaaaaacac
      841 ggtgttctcc actatgccgt tgccaatatc cctggtgcgg ttgcccgcac ttcaaccatc
      901 gccctaacca atgtcactct tccttatatc gaagctttgg ctggcaaagg attcgcacaa
      961 gcaatctctg aagatgaagg cttgcgtcaa ggtgtgacca cttatcaagg ttacttgact
     1021 agcctaccag ttgctcaagg acttaatcgt gactacactg atatcaatga tttagtataa
     1081 attttgaaaa gaaaagggtg acttcgcaag tcctacccac tgtgctttgt gtcatcagct
     1141 attacatcgt tggtttattg tactgtatac tttgcaactg gagactttcg ttccagactc
     1201 aattgtgcat aagaaactct aaattgaata aagtcaacag agtttcgccc aaccacttcg
     1261 tcttgtaatg acaattatat aaaccaaagg aagctgagct ctttagtccc agcttctttt
     1321 tatatataaa attttacccg tgcaaagaca gggccttagc agacttcttt tttacttcgt
     1381 tcacccttgc tttttctttt taggtttggg cgttggcagt tggttataca tagctaaaat
     1441 caggtcttat agaaacatct tattatcaag ttcttccact caaatcattt ctttggcacc
     1501 tttgtatgga aactcaaaag aagattggtc aatcttatct aagactgctt gcacgggttt
     1561 aactaaaaag cgatcgtcat aaatgccgcc aataatcttg ccgcggaagt aaagaatata
     1621 ctcccccatc atggaacggt aagtcacatc atctaatcct gataattgtt ccaaaacaaa
     1681 ttccaaatag ttcttacttg atgccatttc taatcttcta ggctctgttc agcgataaca
     1741 accgtataga gttcttgctt aacctcgcat ccaattgatt taaagccctg cttttcccaa
     1801 aaatgctgag attgcggatt tcccttaaca taagccaaac gtgcctttcg aaagttctta
     1861 gcaaaataag ctagtgcttc tgtcacaata tgactaccaa tcccttttct ctgataggct
     1921 tgatcaacca taaacaaacc aataaaaaca gtctcctcat caggatatgc atagacaaaa
     1981 tccataacag ccacaaggtc agatccattc caaaatccaa caaaaaactt atcagcctta
     2041 gctttacctt caggtagaca aagcatgtcc tcttttacag ttgcaaaatt tggctctggt
     2101 ggacaatgct gaaaatacag aggattactt tcatataaag ataaaatact tggaatatcc
     2161 ttttcagtta gtatcctaca actgtaatac ttagatagtt ggtcaatcat cttttcaaat
     2221 tcctactttc ttgtgccctg tgattatgac acaggaagat gcactgatcg tcatcagcca
     2281 cataaaagtt ctttccatcg tgcctaatcg ttgtctcaga cctttggata aaacctttag
     2341 cctatacaac tggattttcc tctctcaaaa gtatattctt ttgcaggcga acttcctcaa
     2401 aatcagtcgt gtgcaacttc agtagaatat tcataggctc ggataatctg agcgacaact
     2461 ggatggcgaa ccacatcctt ggctgaaaaa tgaacaaagt caatctgatg gatgttcttg
     2521 agtttctctt gagcatcaat caaaccggac ttgacattac gtggcaggtc aatctgactg
     2581 atatctccat tgacaatcat cttagaatga aagcctaaac gcgtcaagaa catcttcatc
     2641 tgcatgatgg tcgtgttttg cgcctcatcg agaatgacaa aggcatcatc caaggtccgg
     2701 ccacgcatat aggcaagggg cgcaatttcg ataatttcac gctccatgag acgagtcgtt
     2761 tggtctttcc ccagaatctg atacaaggca tcataaacag gtctaaggta aggatctacc
     2821 ttctccttaa gatcacccgg aagaaaacct agactctctc ctgcttccac cgctggacgt
     2881 gtcaagataa tccgcttgac ttgcccacgt ttaagggcag tcactgccaa agtaactgca
     2941 agaaaggtct tccccgtccc tgcaggccca attccaaagg tcacatcatg ctgtttgaca
     3001 ctgtccacat aaagtttttg acctaacgtt ttaacgcgga tcggtttccc agtattatcc
     3061 ttgataattt cttcttcgta aagggcgaca aacttatcaa tttcatcgtt tttgaccatg
     3121 ctaattgcag tcaccacatc tggcgtacca acggtcatcc cacgatttac caagaccatc
     3181 aaagcctgaa taacttgacg ggcttcctca caggcagact cttctcccaa aacctggaca
     3241 atctccgtac gagcatgaat cacaacatca agctcttctt ccatcaaacg aagatggcgt
     3301 tcattggaac caaaaagatg aaacaggtca tctggatgac tcagttgaat gtctattgaa
     3361 tgttccttca aataaagaac ctctctaatc cttttatttc tttttattat agcagaggga
     3421 tggagaaatt actagcccaa acctagtgaa taaatgctag tgttctaagt attcttgcca
     3481 gatagcgtca aagtctccta ggttaaaaga gaaactggca tgctcctcca aaaagcgact
     3541 gacctcatca aaatcatctg tgtgttttgg aaaagctgcc tcttcaaaag cgaggtctgc
     3601 caaaattgct ttgggactgt tacttttagg attgcgctcg gtcatgagcc aagtgtaaaa
     3661 tgattttctc ataagcctcc ctaaatcaac tctgtcccaa actggtcctg cttgatttta
     3721 ccagccttca taagaccacc taaagctttc ttgaactgac ctttagaaat gccaaaggtt
     3781 gccttgatgt cgtctggaga tgacttatca tttaaggtca tgaaaccgcc attactttcc
     3841 aaataagtca aaatcatctg agcatcgttt tccaacattt caaaggagcg tggtttgagg
     3901 gagaggttca gagtgcggtc cacttcacgg aaaccaataa cgcgcgcatc taatacttgc
     3961 cccaaacgtg gctctgcgta acgctcgcta ggatgaataa aaccaagcat attattttct
     4021 ggtaggtaaa caaaagttcc tgacagcttg agacggtaaa caatggctgg ccagttttgg
     4081 ttctgcatgt tgttgtaggc aggacgagca agacgttgga agtcttcttg ataagccaag
     4141 aggccccaga tacggtcttt cttatccact tcaagacgga tgtagagttg gtcgcccttc
     4201 ttaggccaga gttccttgag ctcagggaga atatcgagtg acacaacgat ttccttgtca
     4261 ggaaggcctg tatccacaaa gacacccaag tccttacgaa cctctgtgac acgtccccaa
     4321 ccaaattggt cctgagtggc agtcacttct aaggttgtca ggcggagttt ttgcttcata
     4381 tccgtgtatg caaaaccttt gaccgtatcc cctactgtat gttggccttc ttccttagca
     4441 agagcatagg tttgaccatc cttttgcaca aagtaaaaac ggtcgttttc atcgatgatc
     4501 agtccaacga taaaacttgc aagatttgta ttcatatttc cttctttcga ataaaactca
     4561 gccagcaatg ccaactgagt ttttctgttt atttttagac ttccaaaagt tctttctctt
     4621 tgttagcagt catgtcgtcg atgtgtttaa cagcatcgtc tgttactttt tgaatgtctt
     4681 tttcaagagt cttcaattcg tcttcagtga tttcttttgc tttttctcgt ttcttagctt
     4741 cgtccatagc atcgcgacgg atattgcgga cagccacttt agcattttcg ccgaccttct
     4801 tcacttcttt agcaaggtca cgacgagttt cttctgtaag agctgggata accaagcgaa
     4861 tcacagaacc gtcattagcc ggtgtgatac caagatcaga agcgttcaag gcacgttcga
     4921 tgtctttcaa tgaagacttg tcaaatggtg ttaccaacaa aacacgcgct tctggaatcg
     4981 taattgaagc gatttggtta agaggagttt cgactccata gtattctaca tgtacacggt
     5041 caagcaagct tgcattggca cgaccagcac ggataccacc aaattcacga gcaagtgatt
     5101 ggtgagactg ggtcattctc tctttagctt tttcaataat tgcgttagcc atattctttc
     5161 ttattccttt tcttcgatat tatttgaaac tgttgttccg atattttcac caaatacgac
     5221 acgtttgatg tttcctggtt ggttcatgtt gaagacaacc aagtcaatgt cgttgtccat
     5281 tgagagggtt gaggctgttg agtccatgat acgaagacct ttgttgataa catcacggtg
     5341 ggtcaattct tcaaacttaa cggctgtctt gtccttctta ggatcggcat tgtacacacc
     5401 atcgacgcca tttttagcca tgaggatggc atctgcttcg atttcagctg cgcgaagagc
     5461 cgctgttgta tctgtcgaga agtatggtga accaattcca gcaccaaaga taacgatacg
     5521 gcctttttca aggtgacgaa gggcacgtcc acggacataa ggctctgcca cttgttgcat
     5581 ggcaatagct gtttgtacac gcgtatcaac cccaacttgt tgcaatgaat ctgccatcac
     5641 aagagcattc ataacagtcc caagcattcc agtgtaatct gcctgaacac ggtccatacc
     5701 tgcttctgct gcaggttctc cacgccagag atttcctcca ccaataacaa gggcaatttc
     5761 gatacctaag ctatgaactt cttgaatctc ttttgcgatt gtttgaactg tttggatatc
     5821 aatccctacg ccacgttcac cggcaagggc ttcacctgat aacttgatta aaatacgttt
     5881 atacttggga ttcgccattt tcactctcct tctttcatcc tacctatttt atcacaattt
     5941 ctaagatttt tatagtatca tgagcaattc tttcaaaaaa attagacagt caaaaattcc
     6001 tctaagtcgg caagggcacg ctctgcaatt ttttcataac gagccttctt atcacggata
     6061 cgctcgcctt ccaactcctt gatgatccca aaattgacat tcattggttg gaaatgtttg
     6121 ctgtcggcat gggtaatgta atgagctaag cttccaatcg ctgtcgtctc ggggaaaata
     6181 acctcgcttt cttccttgaa gagacgagct gcgttaattc ccgcaactaa gcccgaagcc
     6241 gccgactcaa catagccttc cacccccgtc atctgaccag caaagaagag atttggttgt
     6301 ttcttagaac ggtaagtctg ctcaagaaga tttggtgaat ccatgtaaga attgcgatgc
     6361 atcacaccat aacggacaaa ctccgcattt tcaagacccg gaatcatttg gaagacacgc
     6421 ttttgttctc cccatttgag gtgggtctgg aaaccaacaa tattgtagag gctaccagct
     6481 gcattatcct gacgaagttg cacaaccgca taaggtgttt taaattctcc atcacgaggt
     6541 cctgtatagt cgtctgggta ctcaagaccg actggcttca tagggccata aagcatagtt
     6601 ttaatgccac gtttggccat gacttcgata ggcatacatc cttcaaagta cttttctttt
     6661 tcaaaagaat taagcggtgc ttcttctgca ttgaccaaag cttcatggaa atccataaat
     6721 tcttgcttgg tcataggggc attgaggtag gccgcttctc ccttatcata acgtgatttg
     6781 aggtagacct tgctcatatc gatagtgttg acatcgataa taggcgctgc cgcatcgtag
     6841 aaataaaaac cagcaccgtc attaagagca tgaatctttt cagctaaggc atcacttgtc
     6901 aaaggaccag tagcgataac cgtaataaca tctgtcggca attctgtaat ttcatcacga
     6961 accacttcaa tcaaggggtg gttggcaact ttttcggtca ccatttgaga gaaaccatca
     7021 cggtccactg caagggcacc acctgcagga acacgtgtag cctcagcaga ttccaagata
     7081 acagaaccca agcgacgcat ttcttccttg agaagaccaa ctgcatttgt caaagcatcc
     7141 ccacgcaaag aattggaaca aaccaactca gcaaaattgt ctgttttatg ctggggtgta
     7201 gacttgacac cacgcatttc atatagttta actggaatac cacgctctgc gatttggtaa
     7261 gctgcttcag aacctgccaa accagcaccg ataacattga tataagattg agacacgaca
     7321 ctaatacctc tttgggagtg tgaagttaag attcacattg aaaaagccaa tcagacttac
     7381 gagctttcga gtttcttggc tcaggctgaa aaagtccaca ggactttttc actcccacaa
     7441 atctttctat tttttcttct actagtataa caaaaaaagg gaagaaggca aacttccctg
     7501 tttagtcatt ttcttgatgt aaagagatag tgagtattcc agttaagaat caattatatg
     7561 ctactctata aaatcttttc cacataacgg atcgataggg actgttattc tatctcttgc
     7621 tataaccgta ttatctaaaa cagcataaca ttcaacatag tgatctcctt taaactgtga
     7681 atcttcgtga tattttattt ttacctgaaa aaatagcacc acgctcacaa tttcttctaa
     7741 tagcctcagc ttcaatattt cttactttcc aatagacttc ctgcgaaaca aaatatggta
     7801 tagtagttct atgaatgatg aagcaagtaa acaactaact gatgcacgat ttaagcgtct
     7861 tgttggtgtt cagcgtacca cttttgaaga gatgttagct gtattaaaaa cagcttatca
     7921 acttaaacac gcaaaaggtg gacgaaaacc taaattaagc ctagaagacc ttcttatggc
     7981 cactcttcac tatgtgcgag aatatcgaac ttatgaagaa attgcggctg attttggtat
     8041 ccacgaaagc aacttactcc gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg
     8101 ttttacgatt tcaagaactc ctctcagttc tgaggacacg gtaatgattg atgcgacgaa
     8161 agtaaaaatc aatcgcccta aaaaaagaat tagcgaatga ttctggtaaa aagaaatgcc
     8221 acgctatgaa gtctcaggcg attgtcacaa gtcaagggag aattgtttct ttggatatca
     8281 ctgtgaacta ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat atcggacaag
     8341 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     8401 aaactccacg taaatccagc aaactcaagc cgctaatagc tgaagataaa gcctataacc
     8461 atgcgctatc taaggagaga agcaaggttg agaacatctt tgccaaagta aaaacgttta
     8521 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     8581 gtgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aatgtaattc
     8641 tcaagctgtg agttcattat gatttgtaaa tccgatatat cttcagcagc taaaaacaca
     8701 ttttgaaatg ttccaagtcc gttttcacca aaactatatt ctctcttact atacttactc
     8761 ttattattct ctatatagtt agagtcaagg ttcttaacct cttgaagttc attttcttta
     8821 cttctgaggt taaaatcttt tacttctgaa gttaagtttt ttgacttctg taagtcattt
     8881 tcttttacct gaaatatact cataaagtct ttaacataaa tgatattcgg cttaccaagt
     8941 ccaagcctta ctctttcgat cagtcctatt ccttttttta catcaagctc atctaatgtt
     9001 tttatggcag ttggctttga gatatttctt cttttcataa tttcttcgac agtaaaatag
     9061 ataaatactc tgccttcctt gtctatccag ttattcttaa atgacattcc tgtctgttta
     9121 agaagtatgg aataaaggat aattgcttct gctgataagc cccgaaattc ttctctatca
     9181 actaatatct ccggtacttt taagaagtta aatctttccg cttctctgtt ataaaaatat
     9241 tcaaagtcca tgcaagatca cctcccttct taaaaatttg caaagaaaaa gacgatagtt
     9301 tttcttctat cgcctttggt aaccattttt atgaaatttt ttaaagttaa aaatataatt
     9361 tataatacta tcttcttcca ttttctgatt ttagttctga aagttccaaa aggtgcaacc
     9421 gtatttacat gaataaactt atacacttcc caagtcgctg ttttagtcgc ttcatcagcc
     9481 cactttctca tatgcggttc aaataattct tcctcactca acgaatcaat cattgcagag
     9541 atagaattaa tattttcatt taattttgct ttcaactctt gcagagataa atgagcgtag
     9601 gtatctgtga accactgata taactcacca agttgattcc atttaaattt atccgatggt
     9661 gtttttactt gaagcccctt tctttcatct tcttcccatt taagaaccaa gttggtccaa
     9721 ccaacctgat aagcaaggtt ttctgctgga gttctgtcaa cttcatcagc tctcttatct
     9781 tttaaatttt ctggaatatt atcaaattct aaaatatatt tctcaaatgt tttctctatc
     9841 tcagctttta gttcttcttt attttcgtat gttcgcaaaa aatcaccttc tttctgattt
     9901 atcaatcctt tgatttaaaa tgaccttatt tttctattta taccttctaa gaacgctata
     9961 actgctgctc caaccatcgg tattccgtat gggcttaata aaaaacttaa taccaaagct
    10021 tctataccaa gtgatacatc tttatattat catcactaat taagttaaac agaaacagac
    10081 agaattatta catcctgtct ccctttattg tttttcttcc cagtcgtggt aggcagcgta
    10141 gagttgactc ttattccact ggtaaatctt agctacttcc ttaatagctt gatttttctt
    10201 cataccttgc tggatacgag cttggatttc taagaacaag tcttcctcgt ctttttcttc
    10261 cacacctttg ctggcacctt caacaatcag aagacattca cccttgagag acgtttcaga
    10321 gatgctttcc agcaattcag aaattgtacc tctttggtat tcttcataga ttttggtcaa
    10381 ttccctgacc aagacaacgg agcggtcacc gtagacttct aacatatttt ccaacgtgtc
    10441 tgctacacga tgaggtgatt cataaaaaat ctgtgtttca ggataatctt ttttcgagtc
    10501 aaaaaattgc ttctgctggc ctgattttct cggtaaaaag ccgtaaaaga tatgtggctg
    10561 cggcgctaaa ccactggcaa tcaaggcaga aattcctgca gaggcacctg gaactgtaac
    10621 aactgcaatt tcttcctcaa tagctgcctt aactaaatca tgaccagggt ctgaaatgct
    10681 aggcaaaccg gcatcagaga cctgagcaat actttgccct gctttcaaga aaccaatcaa
    10741 atcaggaatt ttttccttgg cattgtgctc atgaaaactg atctgcttgg tggaaatgtc
    10801 aaaatgcttg agcaaaagcc ctgtattgcg cgtatcctca gcagcaatcc aatctacttc
    10861 tttcaaggtc tggatagcac gaaaagtcat atcatctaga ttgccaatcg gcgttgccac
    10921 tagatacagc ttgccatagg gagactgccc cttaaaactt ttttgaattt gcatgcctac
    10981 tccctgtata acaactcatc acagaacata cattcttcgt cctgctctcg acgttgtcca
    11041 taaaaatcat tacatacgtg aaatccatca cggtaaatac gacggacact ttcgcgaaca
    11101 tgcttggcct tgacgggagc gtctgcttcc acctcaccca agcgttctcg caacttacta
    11161 ttttccaagc gaagagctgt attttcttct accaagctct tgagattttt cttgatggct
    11221 tccacatcgg ctaaggttac caataattgt tgggaaaaat catccagcgc gtcaaataat
    11281 tcttttttgt ccataaaaca gccctttcct ttctttatca ttcatttttg agtttatatt
    11341 tctttcaaga ccagatattc catggcattt tgaaagctga cattagcttg ccacattttt
    11401 ctagcttcta gtaaatcttg tagaatcact cttactctta cctgcaagag gtcctgccca
    11461 cagagaactt caagaatccg taaaacctga tcctgttttt ccttatcatc tgccaagttg
    11521 gctaatttgg caacctgtag ataactttct tttttcttag ctactaacca agtcagcagg
    11581 cgttcacttt catcgaccaa ggtccaaaaa cttgcctgat tagccaactt ttctgcttca
    11641 gctcgcgatt gactaaactt agttaaaaga gtcgcttttt tcttaacaag tcccatttgt
    11701 tctaagagta agatgagttt ttcttcttgc tttttaaagt ggaagatctg agtccgactt
    11761 cggattgtcg gtaacatctt ttcctcatcg ctagtcaaga agaaaatata aacttcactc
    11821 tggggttctt cgatgacctt gagcagagaa ttggctgcgt tgggatgcat tttatccgct
    11881 tgctcgatga taaagacctg ttgctggctt tcaatccctg cttgagaaaa ctgtcccacc
    11941 aattcccgaa tgcgttctgt cttgatgacc tgattgactg gcttaatcaa ggtgacatct
    12001 ggaaactctt cctgttcaat cagcttgcaa cttcggcatt tctcacatgg taagacgcca
    12061 actttatccg tacaaaagag gctcttagct aaaaattgcg ccatttccaa gcttccaaag
    12121 aaacctgaaa agagataggc gtgattgagc tggtcttgtt ctaagatacg gacaaaacgg
    12181 tcaaactgag ctggttgcca agcctttagt tgatcttgtt tcatttggcc aagcccattc
    12241 cgtcaaacaa gacagccttg gtagtttcca caacttgctc caaagggaga ctagcatcaa
    12301 tcttgacaat gcgatttcct tctttttcca ggagagaaag gtagccttga cgaacttttt
    12361 tatgcaagtc caacccttcc aaatccaaac gattaacctc gcggtcacta ttagcagcaa
    12421 tacgagccag cccttcttcc acctcgatgt caaaatagag tgtcaaatcg ggtttgaggc
    12481 catctgtcgc aaactgattg agccagtcaa tggcttcaat atctaagcca cgaccaaatc
    12541 cctgataggc aacagaacta tcgataaaac gatccatgat gaccaacttg ccagcttcaa
    12601 gggctggaag aactttttcc accaaatgct gtctgcgact ggcaatatag agaagtagct
    12661 ctgttttagc atccatctga gtatgacttg gatccaaaat cacttcccga atcttctccc
    12721 caatcaagac tccgccaggt tcacgggtcg tcagcacctt tactcctttt tcctctaaaa
    12781 ttggtagcag agcctctaaa acactggtct tgcctgctcc ctctggtccc tcaagagaga
    12841 ctaaaaatcc ttttgacatg tctaactcat ttctttttta ctacttctat tctatcaaaa
    12901 aaataggggt ttgtgacaat ctttttgtgt cttctcattt catactcaat gaaaatcaaa
    12961 gagcaaacta ggaagctagc cgcaggctgt acttgagtac ggcaaggtga agctgacgca
    13021 gtttgaattt gattttcgaa gagtatcaac caccataaaa gaggcagata aaactacctc
    13081 ttatttacct agttcttgtg ttcgtttgta ggcttgatga actgcatcca tgactgttcc
    13141 tcggaaagca tgcgcttcta ggcttgctac accagcgata gtcgaaccgc ctgggctaca
    13201 gacttggtct ttcaatactc caggatgttg ctggctttct aggaccaatt gcccagctcc
    13261 taccacagtt tgggctgcca ttttcaaggc tgtttctcgt ggtaatcccg tctgaacacc
    13321 tgcatctgcc aaggcctcaa taaagagata gacaaaggct ggtccacaac ctgcaagacc
    13381 tgtcgctgca ttgattaagc tttctcctaa ttcaaccaag agaccagcct tggctaaaag
    13441 ctgacaaaag agctcactgt cctcagccct gcaattagga gacaaggcat aactaatcac
    13501 tccttgcccg atagaagcag gggtattagg catcatacga ataattcggt gttggcttgg
    13561 gataagactt gctagttttt ctaaggtcaa tccagctgcc atcgaaatca aaagaagact
    13621 ttctcttttt tcaaggatgg tctggtattg agaaagcagt tcagaaaact gagcaggctt
    13681 aacacctaga aaaatcacat ctgcttcttc gaatatttct tcattgttag aagtctgacc
    13741 accgaagtta gcgatgaaag catccacctt gacttgacta cgattggcaa ggagaatctc
    13801 atctgacggt ctagcctgca agacagactt ggctaaacta gcacccatat tccccaaacc
    13861 gataaatcca atcttcatcc cttactccct tatctgtcca tcaccagtga ccacatactt
    13921 gtagctagtc aattccttca agcccatggg accacgcgcg tgcaatttct gagtagaaat
    13981 ccccatttca caaccaagac caaattgtcc tccatctgtg aaacgagttg aggcattaac
    14041 atacaccgct gcagagtcca cttgatctgt aaagtatgct gcagcttcag cattttccgt
    14101 cacaatagca tccgaatgat gggtgctgtg ggattcaatg tgcgcaaccg cttcttctaa
    14161 actgctcaca accttaacag caaggacata gtctaaaaac tcggtgtcaa agtcttgggt
    14221 ctcagctgct tgacctgaaa caaactggct tgctttgcta tccaagcgga attgaattgg
    14281 ttccagtcca gcttccttac gctctgcaac cagcatttga tccaagcgag gaaggatgct
    14341 tgctgccttg ttttcatgaa ccagcagaac ctccatggca ttacaaacag aaggacgact
    14401 ggttttagca ttgttgatga tagacagcgc cttgtcttcg tctgcatcct tatccacata
    14461 gacatggaca atcccagtcc ctgtctcgat aacaggtaca atcgcattct caaccactgc
    14521 attgatcaag ccagctcctc cacgaggaat gagaaggtct agatagccct tggccttcat
    14581 catagcataa ctactttcac ggctagtatc ctccaccagt tgaatcacat ttggatgaat
    14641 agtagtcgtc tccaagccct tcttcaaggc tgtgacaatg gcatgggttg tttgataggc
    14701 atccttacca ctacgaagaa caaccgcatt tccactctta agagtcaaag cagccgcatc
    14761 agacgtcaca tttggacggc tttcatagat aataccgatg acacccatag ctacacgttt
    14821 ttttgtgata accaaaccat tttcaagctg acttgtttct aaaacttcac cgattggatc
    14881 tggtaaggca accacttcac gaattcctct tgccatcgct tctatacgat ctgcatccaa
    14941 ataaagacga tccaacatca catctgagat tttcccctta gccgctgcca tatcgagggc
    15001 attagccgct aaaatttcct cagtagcagc cactaagtga tcagccatgg ctagcaaggc
    15061 ttggtttttc acttcttcac tagctgtgtt aatcgatttt ttaacagcct gtacctgttc
    15121 aaattgttct tgtctactca ccatagttta cctctaaaat tctgtaaaaa gtagttggat
    15181 ttcaggagta atggaaatcc agtcgtcacg gtaaatcaag acacccttgg ctttttgaga
    15241 acgcaacata tcctccaaag cagatgctcc aaattgcacg cgtccttttc caagtgattt
    15301 tccactttcc ttatcaaata ctgtcacgat atcaccgtaa gaaaagactc cttctgcttc
    15361 aacgatacca gataagagaa gactctttcc atgttgagag agagcttccg cagccccttt
    15421 atcaacccaa atagaacctt gactctgagc atagaaggca agccattgtt tctgggtacg
    15481 aagccccttc tcttgagcaa caaagtaaga accatcctcg gtctcctctg ccgcctcaat
    15541 catggaatct gatttcaagg atgagcagat ataaacagga actcctgatt ccgtcgcgat
    15601 agttgcagcc ttgattttgg ttaacatacc cccagttccg tttgacgaac cagctccacc
    15661 agccatatca ataatctcac gattgatggt ctcgattctc tccaagcgtt tggctcttgg
    15721 atctgaatta ggatttccag tatagagacc gtccacatct gtcaagaaaa ctaaaaggtc
    15781 tgcttggacc atcgccgcta cttgagcact tagagtgtca ttgtccccaa ccttgagctc
    15841 atcaataacg acactatcat tctcattgat gataggaatt gccccacggt tgagcaaaac
    15901 cgacaaagcc tgatgggcat ttttataacg acgcttatcc acaaagtcat cttgggtcag
    15961 caagatttgt gcagaaacga tttgacgcaa gagaagattg gttgtatatt cttccaacaa
    16021 aagcccctgc cctaccgctg ctgaagcctg tttatcagca attttagtcg gacgcttttt
    16081 aaatcctaag gctccaaaac cagccgcaat ggcacctgaa gacaccaaaa tcaactcatg
    16141 accagcctcg tgcagcatag ccaactgctg ggtaatatcc tttaccttac tacgtgataa
    16201 acttccatcc tcatttgtca gagaagaagt acccacctta aagacaatcc gtttgtattt
    16261 catagtctca ctccgattat tcatatttat ccattataac atgaataaca ggaaatagaa
    16321 aagagttgat aggaaaaaga aggccctaaa accttctttt ctactactgt tctgattccg
    16381 atttgtttac actcgtttca gagctttgtg aagttgagga tgtcaaatct tgactagttg
    16441 aagaatttgt aacactttca tgttgactcg tttctttatt ttcaagatcc tttttcacta
    16501 cttctttgga ttcttttatt tctgaatgac ttgtagtttt aattgtagca gatttctcga
    16561 tcggaacatc cactaaccag gcaccacttg aatccacagt atagccttct ggtgtcttac
    16621 cattcacaag taattgacca ttttctttca agaagtacca tttatccttg tctttaatcc
    16681 aacctatagc tcgtgaacca tctgtcttgt agaaatacca atcatttgcc tttttaagcc
    16741 agccttgctt catagctcct gattcttcta gatagtaatg atgtccagca acttctatct
    16801 cacctgtctt catgatacca gtagaatcca tatagtacca ggcttcttta tcttttaccc
    16861 agcccgtttt catttcccct gatggagcaa agtaatacca ttgcccctta tattgaagcc
    16921 aacctgtctt catagagcca tcaacatcca aataatacca ctgctcttta tcttgaatcc
    16981 aaccaatttc catctggttt tctttgttaa aataatacca gattccagcg attttcttcc
    17041 aatttttagc agcaacacca gagtctgtca aatagaacca acgattgttc cattttttcc
    17101 attgattctg taataagata cccgtttggt taaagtaata ccattcaccc ttaatttcat
    17161 tccaaccaac agcatattct cctgtagaat caggcgcttg ataccaccag tttccatatg
    17221 aactcttatg ccaaccagct tgaaaacttg gaatcggctt gtaggaagtt gaaatgttta
    17281 ctaaaccgtc ttgtcgaata tcaaaaactg ttgcatcata gtctttgctg gctgcgttga
    17341 ttctctcaat tcctcgttct ttgagccaat taacatactc actatcaaca ccatttttcc
    17401 aaggtagact atccgaagtt tgaacaatca aactcggact caaattttta atgaaatcct
    17461 tggtatttga tttgttggta tcatggtgat gattaaactt catcaaatca acttttccaa
    17521 tgagaggacc atacttgtct tctgctccat gaacattatc taaatcgccc ccaaggtaaa
    17581 ttttcttgcc attgactttc accacgctaa tcaaggaatt ggaattgtca tcccaaattt
    17641 tctttaattc acccgatgaa tcagtttcat tttcataatt atagagctga atatccatgt
    17701 ccccaaactg aaaatgagca tccccttgtg tgatattttg aataactgaa acaccttttt
    17761 ctgcagcagt ctgtaaaacc ttatcatagc catacagatt atcccataga cgttcagaat
    17821 tagtaatacg actatcacta tatttcttaa gatagactcg gtcaactgga taggtagaca
    17881 gtaattcatc aacatttcca atatgatcac tgtgggtatg ggtcaccaaa ataaaatcaa
    17941 gtttttggac acccaattcc ttcaaacgac gaaagacacg gtctgtcaga acatgcttat
    18001 aagtggtatt aataccctgt ctccatggat agcgagaatc acttccatct gggaaatcat
    18061 aatcttctcc tgtatccacc atggcaaaat gtccattgct ttcaagaata atcgcatcac
    18121 tgccaccttc ttgaacattg ataaagtgga ttttatttcc tgaactttct tgagcctgaa
    18181 cattcccata ccatgacaaa cctaaaaaag cgcctacaag tgctaaacta gttaatttct
    18241 ttttcattct tactttctca atctctccaa ggtttcctta aaaatctctg ggatatctgc
    18301 tttaaattcc aaggtcttac ctgttctcgg atgagtaaaa cctaaagtct tggcatgaag
    18361 aaattgtcca tgtcctttca aagtcttgcg aggaccatag acctcatcac cagcgactgg
    18421 atggccgata taagccatgt ggacacggat ttgatgagta cgccctgtct ccagttgcaa
    18481 ctctactaag ctataatcgc caaagcgttc caagacgtga aaacgcgtca ctgcaggctt
    18541 ccctttagca gttacagcct gtttcttacg gtctttttca ctccggccaa tcggcgcttc
    18601 aattacacca cgatcattag gcagatttcc atgaacaatc gcccaatatt tgcggagaga
    18661 ctttttatcc ttgagttctt gggcaagtgc tagatgcgca tcatcgtttt tagcaatcat
    18721 gagaagacct gacgtatcct tatcaatacg gtgaacaatc cctggacgca gaaccccatt
    18781 gatacccgac aagtccttaa tatgatacat gagggcattt actagggttc cactggtatg
    18841 accagcactc gggtgcacaa ccattccctg aggtttgtta acgacagcca catcctcatc
    18901 ttggtagact atttctagcg gaagatcctc agccacatac tctaatacct ctggttctgg
    18961 cacatggtaa gtgacgacat caccctcttg gactgtgtat ttagctttct tgacttgacc
    19021 attgaccaag acctggcctg atttaatttg ttcattcgcg agactacgtg ataattctga
    19081 caaatctgac aaagccttat ccaaacgcag accaccagtt tcaattttaa tttccattta
    19141 tttcctcttt tagcattgca atcaataaaa taatcactcc aaccgtcaga tagctatctg
    19201 ccacattgaa aattgcaaag ttgataaagt caaggtggaa catatccaca acaaagccct
    19261 gactgaccct gtcaataaag tttccaagac cacccgcgat tattagagtc aaacccaaga
    19321 ccatccagaa tgagtcctcc atgtgtttat gtaaatacca aatggcacct atcacgacaa
    19381 ccagagtaat gacagcgaat aacaactgct gatcttgtaa gatagaaaag gctgcacctc
    19441 gattttgcag gtaggtcaag ctaacgaaat tggggatcca ggagcgcact tcacccagtg
    19501 gaatctgctg gacgatatag gatttgacca actgatccag cccaattaaa agcagtacaa
    19561 tgactgccac tattgctctt tttttcatga tttcctcttt tgatcaaaat attcttgcat
    19621 gacttctacg aagagagtcc cagcttgact aagctccact tcttcacgtt taacatagac
    19681 catgcggtta tctaggttat ccttgagacg aataactgta atgccattaa cactgtcact
    19741 atctaaaaat ccagaacctg tcgcataggc gtccgtccgc tccaaaatac cattcaaggt
    19801 ggcacggtct gtcacattaa acatctgtga gctagcgctg gtatcgacaa agttctctga
    19861 ataataaagg tactcgtctt tctcttgagt gaaacgaacc gttggtaaat ccgctaaatc
    19921 ctccatgact aattcatctt tctgggctaa aggatgaccc tcacggagat aaatatgggt
    19981 atggaaagga atcaattcga tgacctccag acctaatttt tcaacccgtt gcataatccc
    20041 ctttttattt tgattgttga ggtagataat cccaatctca ctatgccctt gcgccacttc
    20101 atctaatatt tgaacagtag ttgattcaaa aatacggaag ttcttatagt caggatagcg
    20161 ctctgaaaag gccgtaatag ttggtggtaa gaagtcatag tgctggctag caacggaaaa
    20221 ttcatctttt tcttcttcag gattggcata ctgattttga aaaatatcaa atcctttaac
    20281 caattcttgc gctttttcat aaaattccat cccacgacgg gtcaagaaag tccctgagct
    20341 ggtccgacgg aaaatcttaa aacccaactc tttttccaaa tcccgaacag aaatagacag
    20401 actcggctga ctaacataca tcttttcagc agcttcacga aaagtaccac tattggcaat
    20461 agccacaaca tagcgtaatt gttgaatgtt catcttctac ccctaacttc tttatctttt
    20521 cattatacca tattttagaa gttttccaaa aaggaaaaaa gaacatccta ttcttcttaa
    20581 ctatcttcac tatctgcctt tctcaagcca accttatttt caaaatcaat tcaaaaaaat
    20641 aactggctac acaccactac aatatcgaaa agaaaaacgt tgactatttg tgaaaaaaga
    20701 aaatgccgga aagttccgac attattttag taagctaact tcctgaaaat aggagcaacc
    20761 acacatccca gaaggcagtg atattaatga gaatatgaac tagtattgga tagtagagat
    20821 ttttagtcat gcgatacaat agagctaaaa taagacctcc actagcataa atgaaaaaag
    20881 caagaggagt taaagcaaaa ttgatatgaa tataaccgaa aataatagca gaaagcaaaa
    20941 catctccgta ccaaggcgag tttttgaaaa aggttgtcat aatcacaccg cgataaatca
    21001 attcctcagc aataggggcg atgaagcaaa cgatgagcaa gaaataaggg aactcctgtc
    21061 gtcccatcat ttctatcgtt tcattcaaag aaatttgatt tgaaggcggg gatatgaaat
    21121 acgaaaagag gaagtcagac atatatgaaa tgatgtagcc cagtaaaagg tagatgaagt
    21181 acctcagctg ccacttgaaa tgaaaaattt tctttcctgc aaaaaccagt agatagatga
    21241 ccgctaagaa aagaactcca ctctccatca aaagaagaat ctgaaaaaat tcacgacttg
    21301 ctggtagata gggctttgcg agataattga aaagcctcca aaaccaagtt gatttgtaaa
    21361 aaattaagga caatactagt aaaatttgaa tagctcgttt tttcatatta aatcctctgt
    21421 tttctcccct tgtttcttca tattcctaat aaattttact taaaatctcg cagcacttcc
    21481 tttgcaaaga tgattacctc ctccaatata tcctaaatca tcggttcctc tgggacaaaa
    21541 tccatgaacc agcagagtta atactggttc tatttcccaa tcgtacctac cattaggatt
    21601 tttaccatat ggatctgctc caccttgtat cagctctaat tcttcatttg ttagatttat
    21661 attttttgtc attaaaatca tgatatattt cctccattat tcttcagatt agttgagtaa
    21721 tctgctactc atacctactt acaaaaaaac tattatatta agttggtttt ttaatttgtc
    21781 tagttgcaac attgacaaac atagtatagc atatctttgc gaaatatcct cttcaaatca
    21841 tgaattgtca tcaaaacatc ttaaactata aaatcaatta gtctcaagct ttctatcaat
    21901 ttcttctcca aaatatgcta taataatagc aaaagataaa gaaggaagac ctatgattaa
    21961 actactagcc ttggatatgg acggcaccct cctcaatgaa gccaaggaaa tcccacaagc
    22021 tcacattact gctattcaca aagccattga aaaaggtgtc aaactggttc tctgtacggg
    22081 tcgccccctt ttcggtgtcc tcccctacta caaaaaactg gagcttgacc tccagaacga
    22141 atatattatt gttaacaacg gttgttcaac tcaccagact agcgactggg gcttggttga
    22201 ctggcaagaa ctgagtccag ctgacatcga atacctctat gaccttgctg aaaagagtga
    22261 tgttcagttg acactttttg acgagtcaca ttattttgtt ctcggtggca aacccaatca
    22321 agttattgaa aatgatgcta aactagtatt ttcagacctg actgaaattt ctcttgaaga
    22381 agcgactagt ggaaagttcc ggatgttcca aggtatgttt ttaggaacaa aagaacaaac
    22441 agacgatttt gagcagcgtt ttgctgaaga gctttgccaa cgattcagtg gagttcgttc
    22501 gcagcctgtc atttatgaag caatgccgct tggaacgaca aaggctactg ctctttcacg
    22561 actagctgag attttgaaga ttgattcctc agagattatg gccatgggcg atgctaataa
    22621 cgatatcgaa atgctccagt ttgcagggct tgggattgca atgggaaatg ccagcgatta
    22681 tgtcaaatct cttgcggatg ccgttacatc aagcaacgaa gaagacggcg ttgcgcgtgc
    22741 tattgagaaa tatattctat aaaaaagaaa agcaaataga cagaagttac tgctatttgc
    22801 ttttttgcta atattttaaa atacggacta atcaatagac aagaatagcg aatcataaaa
    22861 atcgatttac tagatgccat agtatcttat agttgctaat aagaagttag tctagcagaa
    22921 tgaatctctc atttctccca cactaatctg taatttgtct atacatttct ggtcttctat
    22981 ctcgaaacaa gccccagttt aggcgttcac ttgctccctt gtctaagtca taagtagcta
    23041 acagaacagc ttcttcttgt ctttcagctc gttctagaat agctcctgtt tcatccgtca
    23101 taaaggagga accgtagaag tcaagactgg aactctgtcc gccattttcc tcactaggag
    23161 taacctcctc taaaccataa cgattggctg cgatgactgg aacaatattc gctgctgcgt
    23221 gcccttgcat agtacgttgc cagtgaccac aactatctgt atccaaaatt ggctctgaac
    23281 cgatagctgt aggataaaag agcaattcag caccattcaa tgcaagacag cgcgctgttt
    23341 cagggaacca ttgatcccaa cagataccga taccaatctt agcatagcga gtattccaga
    23401 ccttgaaacc agtgttacca ggcgtgaaat agaatttttc ttgataataa tggtcatctg
    23461 gtatatgggt ctttcgataa acgcccagca cttccccatc tgcatcaatg acggcaatag
    23521 agttatacaa gacattacca tctttttcat agaaactgat tggtaaaaca acttgtagtt
    23581 ccttagcaat caccttaaaa tgctgaatgg cagtattttc cgctacagat tgggcatact
    23641 ggtagtagtc atactgacgt tcctgacaga aatagggatg ttcaaacaac tcgggcaaga
    23701 gaataatttg ggctccttgc tcagcagcct gacgtactaa acgctctgcg gtttggatat
    23761 ttgttgccac atccttagcg cattgcatct gaatggttgc aactcttaca tttctcatct
    23821 ttttctccta ttctggaatt tgttgggtga tacagtggat attgccacca cctaagagaa
    23881 tatctctggc tggtattccg acaactttac ggtctgggaa acacttgctg aggatatcta
    23941 aggccacttg gtcgtttaca tcctcaaact gtggaaccaa gacagccttg ttggcgatat
    24001 aaaagtttac gtaggaagct gctagtcgtt cacctgcgta tcgcttttct tctccttctt
    24061 catagatgta gcctggcaaa tcttcttctg tcacaacttg tcgaactgca gggataggca
    24121 atttatgaat ggtgaagtga caaccttttg catctgtttc ctgttctaag agttcgagat
    24181 ctgcttttga catggcatac tggggatcat tttcgtcatc tgtccaagcc aaaacaagct
    24241 cagcaggacc aacaaaggca gcaacattat cgacgtgttc attggtttca tcctgataaa
    24301 taccataagg aagccaaata actttttcag caccaagact ttctaataat gtgttttcaa
    24361 tctcctcttt agtcaggtta ggattgcgac caggactaag caagcaactt tcagttacga
    24421 gaatagttcc ttgaccatcg ctatggattg cgcctccttc cagtacaaaa ggtttagcat
    24481 catagacagg cctttccaag gcctcagcaa aacgactggc tacttggtca tcctcttcat
    24541 aatcttgata aagaccatca taggtgcctc cccaagcatt gaaggcccaa tccacggcta
    24601 atttcttacc tttatcattg acgagaatgg ttgggccagt atcacgcgcc caggcatcat
    24661 tggtgggaat gtctaaataa acaaccttgt ctccaagata ggattgggct tcagatagat
    24721 aggcctgctc caccaaaaga tagactcttt ccccttctgc tatggtctcg atgatctgag
    24781 taaatgctct tttagcagcc tttccttgaa aaggccatga tcctggtcga gtcggccata
    24841 tcatgagggt accatgatgg ggttcgtact ctgctggcat gtgatagcct aatttttttg
    24901 gactgtccat catgataatc tccctttaaa gtcttgatag ccaaaagctt tgagtaagct
    24961 acagtctccc tgttcgtcca tgagatagag acttggcaat ccaataccat taaaggtatt
    25021 atttttgaca aaagaataaa tggccatgtc ttgaaaataa agtctgtctc cgatttggac
    25081 tggattttca aaactataat caccaatcac atcgcccgtc agacaggtat tagaagaaag
    25141 tctgtaggta tgggcttttt cctgtgcctc aaagccattt ctcaaaggtg gacgataggg
    25201 catctcaagt acatcaggca tatggcaggt cgcagaggcg tctaaaacca agatttccat
    25261 accgttttct acaatatcta atacctcagt tgctaaataa cccgcattaa gcgcaatggc
    25321 ttcaccaggc tcgatataga tttcaagatt gtaagttttt cggatacgct tgatttctga
    25381 aatcagcaaa tccacatcgt aaccttctct tgtaatatga tgaccaccac ccatattgag
    25441 ccattttacc tcatgtaagt agggaccaaa ctgttcttct acttctttca aagttgtttg
    25501 taaatcatct gctccctgct cgcaaagggt atgaaaatga agtccgtcaa ccaaatctag
    25561 caaatcactc ggaatcttgt ctatagtaac tccaaagcga gaacctggtg cacaagggtc
    25621 atagagcgcg tgatctcctt gagttgaaca ctgagggttg aggcgcaaac caacactgac
    25681 accagcctct cgacaacgcg aaccatgctt acgcaactgt ctctctgagt taaagacgat
    25741 atggtctgtt atcccaagca attcctccat gtcctcatcc ttgaaagctg gtgcaaaaac
    25801 atggacttca ccaggaaatt cttcccttgc caatttggcc tcatagagtc cactagctgt
    25861 cgtacctgat agatactggc taatcaaggg ataagttttg tagagggaat atgccttctg
    25921 ggcaagcaag accttgcaac cggcctcttc ttgtacatat tgtagaatgc ggcaattagc
    25981 ttctaacttg gccaagtcaa taacataggc tggtgttggt acttgttcta acttcattag
    26041 tccaccattt gtggattttc aaccacaacc catggcaaac catactcatt caaagcttcc
    26101 atgaatggat ctggatctaa ctcctcaagg ttatacactc cagcttgttt ccaagttccg
    26161 ttcatgacta attttgtccc aatcatggct ggaactcctg tcgtataaga aatagcttgc
    26221 gaaccaacct ctgcatagca ctcttgatgg tcgcagacat tgtagatata gatagtcttt
    26281 ttgacaccgt ctttgacacc tgtaaagata catccaatat tggttttacc tacagtacgt
    26341 gggccaaggc tagcaggatc tggaagcaag gctttcaaaa attgaattgg aacaatttct
    26401 tggccgttaa agttaatggt atccgtacga aggagtccaa cattttcaag acatttcatg
    26461 tgcgtcaagt aagattgacc aaaagtcata aagaaacgaa tgcgtttgac acctggaatg
    26521 ttcttggcca atgattcgat ttcttcatgg tgaaggagat acatatcttt ttgtccaact
    26581 tgagggaaat catactcacg cttgatagac atagcttcga cttcgaccca tttcccatct
    26641 tcccagtaag aacctggcgc agaaacctca cggagattaa tttctggatt aaagttggtt
    26701 gcaaatggat aaccgtggtc accgccatta cagtctaaaa tgtcgatata atggatttca
    26761 tcaaaatagt gtttgagggc ataagctgaa aagacactag ttacacctgg gtcaaaacca
    26821 gaaccaagaa gagcagtcaa gcctgcttct ttgaatttct cttgataagc ccactgccat
    26881 gagtagtcaa agtaggctgt aaaaccaagt tccttacaac gtttttcgta gatagcacgc
    26941 cactcagggt cttctgtgtc ttctgcttcg tagttggctg tatcgatata gtgaacacct
    27001 gttgccaaac aagcatccat aatggttaaa tcttgataag gcagagctac attcaaaaca
    27061 gcttctggtt tgtagctttc aatcaaggta atgacctctt ctaccttgtc agcatcaagt
    27121 gctgcagttt caattttagt acttgttttg ccttctagct tcgctttcaa gtcatcgcat
    27181 tttgacttgg tacggctagc aatcataatc tctgtaaatg tttcgctatc ttgacaaatt
    27241 tttgaaatag caacttgggc aacgccccca caaccaataa ctagtaaacg actcattttt
    27301 ttccttcctc ttcttctaaa atgtcctcaa catacttggg caacataaag gctcccacgt
    27361 gtaagtttgc agtgtagtat tctgtgaaaa gctggcgttt tttccaacct tccttgtcaa
    27421 aatctttgac agggtggtat tttttcgatg caaatccaaa caaccaatag ccagctgggc
    27481 tagttggaat atgggcctga taaacccgac tgattggaaa ggcttgattg accttgcggt
    27541 gcatgcttcg gcaggccgac tcatcctcgt caaagaaggg actcccatgc tggtaaatca
    27601 tgatgccgtc ttccttcaga gctcgataac tattgccgta gaattccttg gtaaagagtc
    27661 cttccgtatg gccaaatgga tctgtcgcat cgttgatgat aatatcgtaa tcatcttcgc
    27721 agtttcgcaa aaagcgtagc ccattttggt agtaaatggt aacacgagga tcatctagcc
    27781 ctgcagcaaa gtctgggaaa tactcacgac agacctcgac caacatctca tccggttcca
    27841 cgatatcgat ttgttccagt tcaggataga gtgttaatac ttgggcaaca ccgccgtcac
    27901 cacccccaat aaccaatact ttctttggat ttgggtggac agccatggga acgtgaacgg
    27961 tcatttcatt gtagacgaaa tcatccgcat ctgagaacaa gacatggcca tttaaaatca
    28021 gtattttccc aaaagctggc gtatccaaga cttcgatatc ctgccattca ctttttccag
    28081 cgtaaagttg cttggctgtt ctcagagaca atttgacatc tggagtatga acttcagaaa
    28141 accataaatc catctatttc tccttatatt atatttagcg cagttagcta ctgccaaagc
    28201 ccaagtggta tacttggaat aagccactgt ggattagttc atttcctcca atcgcttgac
    28261 gatttccgaa agggtctaac cacagctttt tgtttcaatt ggtaatgagt ttgataacgc
    28321 atagacgttt tatctcgtct aaggtaacaa ggcaaaaagt tcgtagataa ctaagtagac
    28381 ttgaaatact atatctggag gtactcccat gctttatgtg ggcattgatg tcgctaaaaa
    28441 taaacacgat gttacagcct tgaatgtttc aggaaaactg ttcttaaacc actcactttt
    28501 tcaaataata aagctggttt tgaactctta gatctgtctc ttcgacagct caaccaagac
    28561 tgtctcatcg ctcttgaaga tactggacat tatgccttta atctactgaa cttcctgcat
    28621 gaacaaggat ataaagttta cacctacaat cctttgctca tcaaggaatt tgccaaatca
    28681 ttatcacttc gcaagactaa aacggataag aaagacgctc atggcatcgc tcttaaactt
    28741 ctttctgacc ccaatcgtga acaatttcaa cacgataatc ggcaagtaga cctaaaaata
    28801 ctggctagac atattcatcg tctcaagaaa aacagtctga ttggaaagta caatacactc
    28861 gttgtcttga tatcatcttt cctgagttgg ataaaatcgt tggaaagcat tcagaatata
    28921 cctaccaact cttgacacgc taccctaatc ctcagaaaag gattgaggca ggatttgata
    28981 agctgataga aattaagcga ttgaccgctt ctaattcaag ggctttttgc cgtgctctaa
    29041 aatcatcgcc aaatcatcaa attgaaataa gaaatagttt agataaaact attgactttt
    29101 cttatagttt gtctttctct taatgacgtt gatatgattg acctctggat cttccgtccc
    29161 ttggagggag caaccacgtt ccttggcgaa ttggatatag tcgacaattt ctcgtgtaat
    29221 gcgttcacca ggagccaaga taggaatacc tggagggtaa cacataacaa attctccaca
    29281 gacctgtcca acagaatcat ccaaagttaa actttttctt tctgaataga aggcttcttg
    29341 cggagacagc actaactcgg gctgaatata ttctcctgct atcaaatctt ttccatctct
    29401 tgaatagagt ctcttaatat cagccagagc accaaccaag cgctcgatgt cttggatgcg
    29461 gtcgccgatg gaaatatagg ccaagatatt gccgatatca ccaaactcga tctgaatgtc
    29521 gtattcgtct cgcaagaggt cataaacctc gatacctgtt aagccaatac cctgagtgta
    29581 aactgacaac ttagttacgt caaaatcgca aaccgaaaca ccgtctatta actcttttga
    29641 gtaggcatag tagccaccga tagcattgat ttcacggcgg gcatactcag atagctcaat
    29701 gactttctca aacgactctt taccacgaag ggccaagttg cgacgtgaaa tatccaaact
    29761 agccatcaac aagtaagagg cagatgtaga ctgggtcagg ttaattatct gacgaacgta
    29821 ttcagaattc atctgctccc cgataagtaa aatggagctt tgggtcaaac tcccaccaga
    29881 cttatgcatg gaaactgctg ccatatcagc ccctgcatcc atagcagaaa ttggaagttt
    29941 atcagtgaaa tgcaaatgcg ctccgtgggc ttcatctact aaaaccatca tgccagcttc
    30001 atgagccatt tctgtcaacc cctttaggtc tgaacagatg ccgtagtaag taggattgtt
    30061 gattaggata gccttagcat ctggatggtc ctttatggcc tgtgctactc ggtcattttc
    30121 aagacctaaa gcgataccaa tcttaggatc tacactcatc tcgatataga tgggaatagc
    30181 accacataga accaacgcat tgatagcaga tttatggaca tttcgtggca gaataatctt
    30241 atctcctgcc ttgcaggttg ccagaatcat agtctgcacc gatgaagttg ttccaccaat
    30301 cattagaaag gcatggctag ctccaaaagc atctgcagcc agctcctctg catcacgaat
    30361 aatcgaaata ggatggccta aattatccaa gggtttcatc gaattgacat caatgcctac
    30421 acatttttct cctaagagtt cgacaagttc tggatttccc cgtccacgct tgtgacctgg
    30481 aacatcaaag ggaacaatcc ttttcttgcg taacttcacc aaggcctcat aaattggggc
    30541 ttggttttga tctaactctt tcaaaacata ctcctttcaa tatttttagg accttatgaa
    30601 aactaaggaa ctaaaggttg actcatgaaa aaagagcagg ttttcacctg ctctgcaatc
    30661 ttctgacgtg tttattttgg tttctgttga gtatgtctgt tcccgatgtt tcctaactct
    30721 ctagtagcaa atattacgta ctttattgat cgtttcacaa gatgacgtgt gctttcacca
    30781 cactaaaaat ttatgaatta ggacaagtgt cctaacatca acttataaaa gtaggctttt
    30841 aaccctatca ataatgtggc ttttcaacca cgcttcggca ttcaaccctg cctgtccgta
    30901 ggcatttttt actcgggttt atatttgcta gaaaacatca tctcattttc taagctttat
    30961 tactatatca tgtttttaag aacttgtaaa gtattttttg ataaaaaaca aaaatatagt
    31021 agattgaaac tagaatagta cacttctgct tctaaaacat tattagaaat agattttact
    31081 gtcctgatcg atttgttctg ttcttgtttc attttactat atgttcgtaa atgaaagttc
    31141 tataatgaag ttagccaccc agccctccta aaaattagat ggttcaacta gctgatagct
    31201 cttgtaggca taagaaaaca cctctgtgtt atacttgttg ttcaaccaca aacacaagaa
    31261 aggcacagag atgcaagaca attatactac aaaagccaaa catttgacaa tcgatagccg
    31321 tcgcttaatc gaaagatgga aaaaagaagg gaaatcaaat agagaaattg cctctctgct
    31381 tggaaaagtt cctcaaacta tccacactga aatcaagcgt gggacagtcc gacaatgtct
    31441 tggaaaaggg cgcttcaaag aggtttattc tgccgactat gctcaacagt cttatgaaaa
    31501 caatcgcaag cgctcggtca ggaaatcaag cgtgaccaag gaactaaagg aaaagattct
    31561 ccactatcat aaccaaaaat tttcgcctga aatgatggtg atggttaaag gggttaacgt
    31621 gggaatttca accatttact attggattca tcatggaaaa ttggggttaa gcaaacagga
    31681 tctgctttac cctagaaaag gaaaagcgct taagaaacag gctagcacca actttaaacc
    31741 tgctggtcaa tccatcgaac agcggtctga agctatcaat cttcgcttgg agaatgggca
    31801 ttatgagatt gatacggttc tacttacgag agcgaaaaac tactgtttgc ttgtcttgac
    31861 tgatcgaaag agtagacatc agatcatccg attgattcca aataaaagtg ctgatgtggt
    31921 caatcaggct ctaaaactca tcttaaaaca acacaagatt ctttccatca cggcagataa
    31981 tggaacggaa ttcaatcgct tgtttgatgt attttctgag gagcacatct attatgcgca
    32041 cccctatgcc tcttgggaaa ggggaactaa tgagaatcac aacaggctca ttcgtagatg
    32101 gttacctaag ggaa
//
LOCUS       DBEROT010000026        31597 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.26, whole genome shotgun sequence.
ACCESSION   DBEROT010000026 DBEROT010000000
VERSION     DBEROT010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.26"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(98..2113)
                     /gene="recG"
                     /locus_tag="ACL8CG_001332"
     CDS             complement(98..2113)
                     /gene="recG"
                     /locus_tag="ACL8CG_001332"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGS1343920.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLQTIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKSIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFACKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(2132..3235)
                     /gene="alr"
                     /locus_tag="ACL8CG_001333"
     CDS             complement(2132..3235)
                     /gene="alr"
                     /locus_tag="ACL8CG_001333"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGS1343921.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(3225..3587)
                     /gene="acpS"
                     /locus_tag="ACL8CG_001334"
     CDS             complement(3225..3587)
                     /gene="acpS"
                     /locus_tag="ACL8CG_001334"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGS1343922.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(3632..4663)
                     /locus_tag="ACL8CG_001335"
     CDS             complement(3632..4663)
                     /locus_tag="ACL8CG_001335"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS1343923.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(4665..5696)
                     /locus_tag="ACL8CG_001336"
     CDS             complement(4665..5696)
                     /locus_tag="ACL8CG_001336"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS1343924.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(5777..8290)
                     /gene="secA"
                     /locus_tag="ACL8CG_001337"
     CDS             complement(5777..8290)
                     /gene="secA"
                     /locus_tag="ACL8CG_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGS1343925.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDIITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(8436..8723)
                     /locus_tag="ACL8CG_001338"
     CDS             complement(8436..8723)
                     /locus_tag="ACL8CG_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343926.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(8751..9383)
                     /locus_tag="ACL8CG_001339"
     CDS             complement(8751..9383)
                     /locus_tag="ACL8CG_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1343927.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKFDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(9387..10028)
                     /locus_tag="ACL8CG_001340"
     CDS             complement(9387..10028)
                     /locus_tag="ACL8CG_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343928.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMILYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKV"
     gene            complement(10021..10812)
                     /locus_tag="ACL8CG_001341"
     CDS             complement(10021..10812)
                     /locus_tag="ACL8CG_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343929.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLEKYEDNV"
     gene            complement(10997..11332)
                     /locus_tag="ACL8CG_001342"
     CDS             complement(10997..11332)
                     /locus_tag="ACL8CG_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343930.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYIPLY
                     ALFSLSWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(11472..11807)
                     /locus_tag="ACL8CG_001343"
     CDS             complement(11472..11807)
                     /locus_tag="ACL8CG_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343931.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(11898..13208)
                     /gene="der"
                     /locus_tag="ACL8CG_001344"
     CDS             complement(11898..13208)
                     /gene="der"
                     /locus_tag="ACL8CG_001344"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGS1343932.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(13222..13935)
                     /locus_tag="ACL8CG_001345"
     CDS             complement(13222..13935)
                     /locus_tag="ACL8CG_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGS1343933.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLKQKKLL"
     gene            complement(13932..14828)
                     /gene="dnaI"
                     /locus_tag="ACL8CG_001346"
     CDS             complement(13932..14828)
                     /gene="dnaI"
                     /locus_tag="ACL8CG_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGS1343934.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(14829..15998)
                     /locus_tag="ACL8CG_001347"
     CDS             complement(14829..15998)
                     /locus_tag="ACL8CG_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS1343935.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(15999..16472)
                     /gene="nrdR"
                     /locus_tag="ACL8CG_001348"
     CDS             complement(15999..16472)
                     /gene="nrdR"
                     /locus_tag="ACL8CG_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGS1343936.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            16612..16977
                     /locus_tag="ACL8CG_001349"
     CDS             16612..16977
                     /locus_tag="ACL8CG_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1343937.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            16982..17677
                     /locus_tag="ACL8CG_001350"
     CDS             16982..17677
                     /locus_tag="ACL8CG_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343938.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            17694..18461
                     /locus_tag="ACL8CG_001351"
     CDS             17694..18461
                     /locus_tag="ACL8CG_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343939.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(18814..20013)
                     /locus_tag="ACL8CG_001352"
     CDS             complement(18814..20013)
                     /locus_tag="ACL8CG_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1343940.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(20010..20903)
                     /locus_tag="ACL8CG_001353"
     CDS             complement(20010..20903)
                     /locus_tag="ACL8CG_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343941.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            21025..21216
                     /locus_tag="ACL8CG_001354"
     CDS             21025..21216
                     /locus_tag="ACL8CG_001354"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343942.1"
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            21584..21797
                     /locus_tag="ACL8CG_001355"
                     /pseudo
     CDS             21584..21797
                     /locus_tag="ACL8CG_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            22212..22829
                     /locus_tag="ACL8CG_001356"
     CDS             22212..22829
                     /locus_tag="ACL8CG_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGS1343943.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(22872..23759)
                     /gene="scrK"
                     /locus_tag="ACL8CG_001357"
     CDS             complement(22872..23759)
                     /gene="scrK"
                     /locus_tag="ACL8CG_001357"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGS1343944.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(23908..25791)
                     /locus_tag="ACL8CG_001358"
     CDS             complement(23908..25791)
                     /locus_tag="ACL8CG_001358"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGS1343945.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            26168..27622
                     /locus_tag="ACL8CG_001359"
     CDS             26168..27622
                     /locus_tag="ACL8CG_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS1343946.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGNLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSHAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            27603..28568
                     /locus_tag="ACL8CG_001360"
     CDS             27603..28568
                     /locus_tag="ACL8CG_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1343947.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(28603..29877)
                     /locus_tag="ACL8CG_001361"
     CDS             complement(28603..29877)
                     /locus_tag="ACL8CG_001361"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGS1343948.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMAILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VVLSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(29877..31049)
                     /locus_tag="ACL8CG_001362"
     CDS             complement(29877..31049)
                     /locus_tag="ACL8CG_001362"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGS1343949.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(31180..31428)
                     /locus_tag="ACL8CG_001363"
     CDS             complement(31180..31428)
                     /locus_tag="ACL8CG_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343950.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(31496..>31597)
                     /locus_tag="ACL8CG_001364"
     CDS             complement(31496..>31597)
                     /locus_tag="ACL8CG_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS1343951.1"
                     /translation="TFKMFSTTYRNHRKRFGLRMNLIAVIINHELGF"
BASE COUNT         9266 a         7067 c         5976 g         9288 t
ORIGIN      
        1 catccacaac ctcaaaacag tgttttgagc aacctgcggt tagcttccta gtttgctctt
       61 tgattttcat tgagtataag ttttccttag agaaagctta atccagatgt tctttctttt
      121 ccagatgaag ggcaatcatg cgccactctg gatcttcttg ccaagcttct atagaactaa
      181 tgtagctagc aacctttctt gcttcttcta aaatcggaaa atcttcgata atatcagcca
      241 cttggaactc tggaagtcct gactgtctgg ttccaaaaat ctcaccagaa ccacgcattt
      301 tcaaatcttc ctccgcaagg acaaatccat tggtcgtttc tgtcatgatg cgcatgcggt
      361 ctttcccaga atccgtcttg ggattggcaa cgagaacagc gtaggactgt ttgtcccccc
      421 gaccgacacg acctctaagc tggtgaagtt gactgagacc gaagcgatcg gcatccatga
      481 taatcatgac agtcgcattg ggaacgttga ccccaacctc aataaccgtc gtcgaaacca
      541 gaatatccgt ctttctctcc ttgaaatcct gcatgatctg gtctttttcg tcactcttca
      601 tcctaccatg tagaagagcc acctctgcct tgcatgcaaa atgagtcgtc aactcctctg
      661 ataaggcaat ggcatttttc aaatctagag cttctgattc ttcaatcaaa ggagagatga
      721 cataggcttg ggaacctttt tgaatttccc cctctaacca agtcaagacc tgaggtagtt
      781 gctcatgttt gatccagcgc gtcacaatag acttccgacc tgctggcatc tggtctataa
      841 tggaaacatc catatctcca aaggctgtga tggcaagcgt ccgtggaatg ggagtcgccg
      901 tcatcatgag gacatctgga ttgtcacctt tttcccgtaa aatacgcctt tgccctacac
      961 caaaacggtg ctgctcatcg ataataatca aaccaagacg agcatactcc accccatctt
     1021 gtatcagagc gtgagttcct ataatcaaat cagcctcacc cttggcaatg gtctgcaaga
     1081 cttctctctt ttctgcagct ttcaaggaac ctgtcaagag agccaatttc aaattgggaa
     1141 aaaggttctg taaactctca aagtgttgct ctgcgaggat ttctgttggt accattaggg
     1201 cagcctgata acctgctgtc actgccgcaa acatggccaa gccagcgact accgtttttc
     1261 cactccccac atccccttgt aggagacgat tcatgtggtg gtcggacttc atatcagtta
     1321 aaatttcctg caaactcttt tcctgagctt gggtcagggc aaaaggaaga cttactttaa
     1381 ctgctgtcac tttttcctga gaccaattca gaaccagacc acttccctga actctatttt
     1441 cagacttgag cgtctgcaac tgcatttgga aataaaagag ttcctcaaac ttgatacggc
     1501 gaagagcctg cttgtattct gccaaatcct ttggaaaatg catagctcgg actgcctgac
     1561 aacgggacat gagtttgtat ttgtctagta aagactgggg cagattttct tctatcaaga
     1621 ggtccagtcc ctgatcaaaa gccgtcttga tgaccttaac cagactggcc tgactgattc
     1681 cctgagccag acgatagaca ggctggaggt catcttctac ctgagccaga accttcatcc
     1741 cagtcagact agccttagcg cggtcccatt ttccaaagac agcaagggtt gctcccaact
     1801 ctattttatc agccagatag ggctggttaa agaaattcac cgcaaaaacg acctctccct
     1861 gcttgagact aaaacgcagg cgattgcgct tgaaaccata atactggaca ctagcaggag
     1921 tcactacctg accagaaaga actgccttct caccgtcttc cagctccagc acctgcttgg
     1981 ttttgaagtc ttcataacgg aaaggaaagt agagcaagag atcttgcaag ttttcaattc
     2041 ctagtttggc gtatttttct gctgactttg gtcccacacc aggcaagaca tgcaagggtt
     2101 gatgtagatt catgctccac tcctttcttt tctaataata ttctctcgga atacggtcgc
     2161 tgaggaggca aaccacctca tagttaatgg ttacgcggta ggtcgctacc tgagttgcag
     2221 tgatttcctt atccccattg gagccaatca aggttacctt ggttccgagt gggtaaggct
     2281 taggcaatcg aatagtgatt tggtccatcg aaaccctgcc gacaattggg caagcttggc
     2341 catctaccaa gacagagaaa ttttgcatgt ctcttgtcca tccatctgca tacccgattg
     2401 gcacggtcgc gatgacttgc tcgctatccg cttgataagt tgctccatag cccatgcaag
     2461 ctccagctgg aactgtcttg acatgaacca gagcagactc caaggtcaag gccggtatca
     2521 aatcataagg caaatccaag accgctccac ttggattgag gccatacatg gcatctccca
     2581 tacgaaccgc attgaaaata gtctctacat gccaaagagt cgttgcagaa ttgctagcat
     2641 gaaccagctc tggaacttcc ttcatactag ctaaaatagt tttaaaccgt tctaactggg
     2701 cattaaaata gtcatctgat tcctcatcag cagtagcaaa gtgggtaaag attccttcaa
     2761 cacgaacacc gtgttgttgg agcaaatctt gagcctgctc aacctcactg gcctctctaa
     2821 aaccaatccg tcccatccct gaatcaatct tgaggtggac tgtcaatcca gttaggtcca
     2881 cttccttatc taagagtgct tgaatccact ccagtccagc cactgtcaag gtgaagtcat
     2941 attctttagc tagagcaaca gcttcgattt cagaaactcc taaaatgagg attggcttgc
     3001 tgagtccagc ttgtctgagt tcaatggctt catcgatatt ggaaacgcaa aagccatcaa
     3061 catcatcttg aattgccttg gcaacggcaa cagctccatg accataagca ttggccttaa
     3121 ccacagccaa cttgagcgtt ccttgaggga tatgagcccc catttgctga atattttgtc
     3181 gaatagctcc cagatgaatc agagccttgg ttggtctatg tggactagct ttcatgattt
     3241 tcctccaaaa tgacactggc tgtcacaaac tgatcggtgt ggctgataga cagccaaatc
     3301 tttcctgaaa atggtgcctg actaaaataa ggcgccccac gttcattgtt caagacttcc
     3361 aaatcctgaa aaccgagctt gctaatgccc gttcccatag ccttggaaaa ggcctcctta
     3421 gccgaccagc gaccagctaa atattctatt tgcctgcgtc ctttgagact ggtgaagcgc
     3481 tccatttcct gagcggtcag tacacgctta gcaaatcctt catgtcgtgt aactgcgctt
     3541 tctatcgaag ccaattcttc gatgtcaatt ccgtgtccaa ctatcattct catcaaaagg
     3601 agttgagatt ccccaactcc atccttttca cttattttgt caaggtaaca taaatctctt
     3661 ctaccaaggc ctctgtattt tcccaaccta ggcaagggtc agtaatagag caaccaaaga
     3721 tctctggttg gttttgacga ccatctgcta ggtaagattc aatcataaat cctcgaaccg
     3781 tctttttaat tttctcattc caatcacgat tctgcaaggt ctggcgaaca attcgaatct
     3841 gctccatata ttgcttgcct gagttatcat ggttggtgtc aatgaggata aaaggatttt
     3901 caagtcccat ggtttcatag cgttcaatgg cttggagtag gttttcatag tagtaattcg
     3961 gcatataatt gccatactcg ttgactgctc cacggaggat aacatgggcc aaaggattac
     4021 ctgatgtctc aacttcctgc ccatgataaa ggaaggtttg cttgttttga gcagcataga
     4081 tggcgttaaa cataacaccc aaatttcctg aggttggatt tttcatccct actggtgcat
     4141 caatcccaga agccacaaag cggtgctctt ggtcttccac agaacgagct ccaacggcat
     4201 ggtagctgac caagtcatcc accaagatca gatttgacgg ataaagcatc tcatctgccg
     4261 ttgtcaaacc agtctctgta atcacgcggt agtgcaactg gcgcacagcc tgcaagccat
     4321 taatcaggct tggagcctta gaagtatctg gctggtgaac taatccttta tagccgtctc
     4381 cattggtacg aggcttagca gtatacacgc gcatgaccat gaaaatctta tccgctacct
     4441 tcttttgcaa ggcggataaa cggcgagcat attccaagac cgcctcttca ttatcagaag
     4501 agcaaggacc aatcaccaag agaatacggt catcttcccc tgaaataata tctgccaatt
     4561 ccctgtcacg gctttccttg agtctcaagg cttccgcaga caattgggtt tcagccttga
     4621 tgacttccat atcgatttct tgaccttttt caataaatgc catcttattc tcctaacgtt
     4681 ttgtaaattt ctctgacaag agcttctgtg ttatcccaac ccaggcaagg gtctgtgata
     4741 gacttaccaa atacttctgg ctcattttgt cgaccatctt ccagataaga ctcaatcata
     4801 aaaccacgaa cgaactgctt aattttttca ttccaagcac ggttaatcaa ggtctggcgg
     4861 acaattcgga tctgttcaat atactgctta ccagaattgt catgattggt atcaatgatg
     4921 ataaaaggat tttccaagcc cattttctca tactgggcaa tggtatcaat taaattgtca
     4981 taatagtagt tgggaatatt ttttccatac tcattaagag caccacgaag aatagcgtgt
     5041 gaaagcgggt tcccagttgt ttctacttct tttcctaaga aaaggaaact ttgtttgttt
     5101 tgagcagcat aaatcccatt aaacatgaca ttgagatttc cagaggttgg atttttaaaa
     5161 ccagtagaaa atcctgcccc acttgccaca aagcggtgtt gctggtcttc aactgaacgg
     5221 gcaccaactg ccatgtaaga aatcaaatca tctacaagcg gaaggttttc aggataaagc
     5281 atttcatcag cagttgtcat ccctgtttct gtgatgacac gatagtgaag atggcgaacg
     5341 gctttgattc cattgataag actaggcgct tctgtcgcgt taggctggtg aatcaagccc
     5401 ttatagccat ctccgttggt acggggtttg gcagtataaa cacgcataac cataaagata
     5461 cgatctgcca cttcttcttg taggactgcc aaacgcttag cgtattcaag gacagcttct
     5521 tcgttgtcag atgagcatgg cccgattacc aagagaattc gctggtcttc tccacgtata
     5581 atggcttcta gctcttgatc tcgctgtgat ttcctctcca aagcctgacc ttctaatttt
     5641 gacaaggcac gaacttcttc tatatttatt ttagagcttt ttgctgtaaa taccataact
     5701 catctcctta taaagcaaac ggatacccag taaaaattta cttttcacaa gatatccgcc
     5761 tctaaactat ctcattttat tgtcttttac cgtgacagtt tttaaatttc ttaccagaac
     5821 cacatgggca aagttcattg cgtccaatct ggctcaaatc caaatcttct ggcatacttg
     5881 cttggtgagc agcgatattg cgagtcgctg ttgtactgat atgacgttct gcctgtggtc
     5941 tttcttgttc atgaatttgt gctttcatca tcaagcgtgt cacatcaaac tcaatcgaac
     6001 caatcatatc attaaacata cggaaacctt ctgcctgata ctcaacaaca gggttgttct
     6061 gagcatagcc acgaagtcca accgcgttac gcaattgatc aagggcatcg atatgatctg
     6121 tccacttgtt atccaccact cgtagaatca aaactttttg gaattcttta actgcttctt
     6181 catcgcgtag ttttgaaacc tgactatcgt aaaccttcaa ggcacgttgg aaaagctctt
     6241 ccttgatggc cttatcagac aagcctgaca agtcttccat cgtaatagaa tcttcaggaa
     6301 gcaagttgta cttagcaaag ttcaaaattg cctctagttt ttcatcttgt ttggcacgcg
     6361 catgaccatc aacgacacgt tcaatcgtgc gcttaatcat agactgaatt tcaggtgcca
     6421 agtcacgatc tgcagtgatg atatcgtaac gttgagcata gataatctca cgttgttcac
     6481 gcatgacatc atcgtattga aggacttgtt tacgggtatc gtagttattt ccttcgacac
     6541 gtttctgagc tgcttcaacc tgacgcgtca acatgcgaga ctcaatcgcc tcttcagaca
     6601 tgttcaagcg ttcaaagatt cccttcaagc gttcagaacc aaaacgtttc atcaaatcat
     6661 cttcaagaga taggtagaat tgtgactcac ctggatctcc ttgacgacct gaacgtccac
     6721 gaagctggtt atcgatacga cgactttcat gacgttctgt accaataaca caaagtcctc
     6781 caagttcacg aacaccttca ccaagcttga tgtcggtacc acgacccgcc atgttggttg
     6841 cgatggtaac ggcaccacgt tgaccagcat tcatgatgat ttgggcttct ctatagtggt
     6901 ttttggcatt caagacttcg tgaggaacac cagctgcgac caatttctta gaaatgtagt
     6961 cactagtttc aaccgctact gtaccaacca agacaggttg acccttttgg taacgagcct
     7021 taacgtcttc gacaaccgct ttaaacttag attcgatact tgcataaaga aggtctgagt
     7081 ggtcaatacg ttgaacagga cggtttgttg ggattggaat aacacgaatg ttgtagattt
     7141 cacgaaattc ttcttcctca gtcttacctg tacccgtcat accagacaat tttttgtaca
     7201 tacggaaaag gttttggtac gtgattgagg cagatgtctt ggtttcatcc tggattggca
     7261 caccttcttt ggcttcaata gcttggtgca atccatcaga ataacgacga ccttccatgg
     7321 tacgacctgt aaattggtcg acaatcaaga tttcttgctc ttcgctcacc acatagtcaa
     7381 tatcgagaag catgatgtag ttggcacgaa gggcgttatc gataaagtgg gtcaaagcca
     7441 cgttttcgat gtcatagagg ttttcaagtt tgaagtagct ttcagccctg tcaatccctg
     7501 aatcagacaa accaatagtc ttagactgca catcgatgat gtagtcatct ttgttcaaag
     7561 attttacata gtggtctgcc atgtgataca actgactggt ttcaaccgca ttggcacctg
     7621 atacaatcaa aggtgtacga gcctcgtcaa tcaagataga gtcaacctca tcgaccaagg
     7681 catagttaag cggacgttgt accatgtttt cagcgcgaac gaccatgttg tcacgaaggt
     7741 agtcaaatcc gatttctgag ttagttgagt aagtaatatc acactcatag gcttcttttt
     7801 tctccattgg agatttggta gccaagttaa tccctactga caaaccaagc caagagtaca
     7861 attcacccat ctcagtcgcg tcacgttctg acaggtattc attaaccgta actacgtgaa
     7921 cccctttacc tgaaagggca ttgaggtata ccggcatggt cgcagtcaag gttttccctt
     7981 cccctgtacg catctctggc acgtcaccat ggtgaagaac aatccccccc atgacctgaa
     8041 ccttataagg gaagagacct aggacacgtt tggcaccttc acggacaacc gcaaatgctt
     8101 cgtaaagcaa tgaatccagt gattctccat tttgataacg ttccttaaat tcaactgttt
     8161 ttgcttttag ttggtcatca gtcaaagcag ccatttggtc ttcgtatttg aaaaccttgt
     8221 cagccatctt ttccagacga cggatttctc ctttatcatt ttcgataatt gtttttaaaa
     8281 tattagccat gtttttcctt actttaaatt ccgaatattt tagaatgttc ctttaatttt
     8341 agcacaatta ctgattattt tcaaggaaga atccccattt tgaaaaggaa aaagaggtta
     8401 gttttcaagc taacctctcc gacttttatg actgtttaat tgccaaaaat tggcaaaatg
     8461 gcaaatgtga taaataagtt aatccaaaga gaaagacagc aaatcagtcc aaaaacaaag
     8521 agactgactt tcttggacag caaggccatc aaaatggaca gaattccaaa aactagcaag
     8581 actttctgta tgatgaagat gtcaatcctt acccccagaa tcgctctatc ccaagggata
     8641 aagaagaaag acagccagat cagcagaact aaaccaatat aaaccttgga atagcgtgta
     8701 ataaatgatt ttagatgtgc cataagccat ctcctaggat tgtatatcct ttacatttgt
     8761 atatgtccat tttcgacaac taatacatct gtacaaaggt ctgaaatatc ttccgatatg
     8821 tgcgacgtca ggataaccag accattttct tttttcaggt aagataaaat gacctgtttg
     8881 gttaacctca cactcttctc atccaaagca ttcataggtt catcgagaaa gagtatagaa
     8941 ggagaggaaa taaaggcttg aatcaaggcc attttttgct ttgttcccaa ggataaatga
     9001 cggtattcaa cgtcttcaaa ttcctgtaaa tcatagtatt gaatccaata ggcaattctt
     9061 ttttccgtaa ctttagatga aaaatacctt aacagttcca aattttctct cagggataaa
     9121 tgagataaaa actcgacttt ttcaattaaa attcctgcat cctgaatata atgatttttt
     9181 atcccgtaaa ctttcccgtc ttgaagaact tttcctttgt caaacttaat ataaccagca
     9241 agtatcttta aaagaaccgt cttgccagat ccattatcac ctttaagtcc ataaattttt
     9301 cctgattgaa acaccaaatt caactgattt aaaataggtc ttttcccata aattttctgt
     9361 ccatttataa tttcaagtct catcgtttat actttcttaa atttctcttc caagcgacta
     9421 acaatcaaca taactaataa gcttaagagt agtaaataca ctgttacaat atgatccatc
     9481 atccattctt gtcccacaaa tgctaaaaaa tagagaaaaa aggaaaaacc agcgcccgca
     9541 ctaatcagtg ctatcagata agacagtagt aagtacaaaa tcattaactg agcaagtaaa
     9601 aagaaaagtg cgactgtttt gaaatgaatt cctagcggaa gtaaaccaag aaaccagaca
     9661 aacaaatctt gagtaaaaaa tttagaaatg acaaccaatc gtttccttgt ataatcgaaa
     9721 aaggagcttg attgatagcg aatcaagtga tggtaatggt ctgccaaatc actttcaagt
     9781 aaaatgacag agagccatcc taccatgaaa agcgaaaggt ttaacaagag tttggggatt
     9841 tctaaattcg cttcagaata gtcattatag gaaaaaattg aaatcaattc tctcttgaaa
     9901 aagataacag catcctgctt ttgaaccgct gttgacaata gatggtttat caaaatcatc
     9961 atcagaacta tacgaagtag taaaacaatc tttctcttta gccaaatatt gttaaaattc
    10021 ttaaacatta tcttcatatt tttcaagcac catataaggg acaacataaa ggatataagg
    10081 agtaaagagt ttcatcaaac ttacatcccc atagctagct tgcatcaaac tcgtcatagg
    10141 aaccatatag taaggcaagg cactatagag cagcatagaa ccaagccaaa gaaacatcaa
    10201 ataggtgatt gccgaacgag tcacattccc cacataatca actatttgta aaaaatagat
    10261 tgcattgatg aaaataccga ttagtaggac acaagtaaag aacaaatagc tttttatctc
    10321 tccatctagg agtctttgta aaccacttcc atcagaaaat agagaattcc atccaagagg
    10381 agaaaaagtc ccaaagaaat aggttacaat tgcaattatc agcacagtca ctaaatatat
    10441 caaacaaggg atacttgcaa cttgcaaagt caactttctt tttaaccctt gataactcac
    10501 ttctcttcca atactcaatc gtaaaacttt atttttcagc tcaatatatt gaaaacctag
    10561 caaaacaatg atgattggaa taataaatga ttgataaaaa cctagattga actggagaat
    10621 acgaaaatct aatgctgatt ttaataagtc atttttaatt gcttgtccat cgaatttagc
    10681 tagatcgggc gcatgaatat caaaaaagaa ataagtcatc aaaacatcac gataaaccaa
    10741 agcaagaaaa agcaaagtaa gcaagacata aacaaattta tgccttgcca aagttaagag
    10801 aggaatcttc ataagccacc tcctacaaat agaaagtaat ataatactca atgaaaatca
    10861 aagagcaaac taggaaacta gccgcaagtt gctcaaagca ctgctttgag gttgtagata
    10921 agactgacga agtcagttac atatataatc caaggcgacg ttgacgtggt ttgaagagat
    10981 tttcgaagag tataaatcaa tgccttccgc ctttagactt ccctagttcc cgtctcaagt
    11041 caagcatttt tttgaaacag atatagtcta accagtcact agcaaaagcg ataagtagta
    11101 ataatagcca aataccccat aacttgatat ctgtcaaatt tctcaagacg atattgaaaa
    11161 acagaactga aaaaactgtc caagaaaggc taaaaagagc atagaggggg atgtaaatcc
    11221 agtaaaaata gtaaaaaatt gggaaaaatt tactttctct attatccttg tcaatccagc
    11281 tgaaaaagta aaaacagggt aataagatta tcattttaaa caagtgttcc atcacaagcc
    11341 tcctttttta aattgttttc tttagtttcg ttctattaaa tgttattacc aatataaacc
    11401 ttggaatagc gtgtaataaa tgattttaga ggtaccataa gccacctcct acaaatagaa
    11461 accgatataa atcaatgcct tccaccctta gacttcccta gttcctgtct caagcgaaac
    11521 atttctttga aacaggaata agttaaccaa ttcataccaa tagctagcag aataaaaaga
    11581 aaccaaatgc cccataactt gatatctgtc acatttctca agacggtatt gaaaaacaga
    11641 actgaaacaa ctgtccaagc aaggctaaaa agagaataga aggggatgta aatccagtaa
    11701 aaataataaa aaattggaaa aaacttacta tttctgttgg ccttttcaat ccagttatca
    11761 aaataaaagt acggtgctaa aagtaagaat ttaaacaaat gttccatcac cgacatcccc
    11821 ctccttcttt tgatagcgtt ttctattatt ttattatatc aaaagaatct ggaaatgtca
    11881 ttccagattc tactttttta tttacgcttt cttgcgatga gatgaatcgg tgttccctca
    11941 aagacaaagg ccttgcggat ttgattttcc aagaaacgta ggtaagaaaa gtgcatgagt
    12001 tcttcttcgt tgacaaagat aacaaaggtt ggtggtttgg ttgccacttg ggtcgcatag
    12061 aaaatcttga gacgttttcc tttgtctgtc ggtgttgggt tgatggcaat ggcatccatg
    12121 atgacatcgt tcaagacagc tgatggaata cgtgtatttt gactttcgct gatttgctta
    12181 atcatcccag gaagtttgtg gagacgttgc ttggttaaag ctgatacaaa gataatcggt
    12241 gcgtaaggca ggtattggaa ctgctcacgg atatcttctt cccagttttt catagtgtgg
    12301 ttatcttttt caagcgtatc ccacttgttg accacgataa tcatcccttt accagcttca
    12361 tgagcaaatc cagcgatacg cttgtcgtat tcacgaatcc cctcttccgc attgatgacc
    12421 attaagacca catctgaacg gtcaatagca cgcatggcac gcatgacaga gtacttctca
    12481 gtattttcat aaaccttacc agacttacgc ataccagccg tatcaatcat ggtaaactct
    12541 tgaccatctg tatctgtaaa gtgggtatca atggcatcac gagttgttcc agcaacagga
    12601 ctggcaatga cacggtcttc tcccaagata gcattaatca agcttgattt tccaacgtta
    12661 ggacgaccaa tcaagctaaa cttaatgaca tctggatttt cttcttcata ttcatttgga
    12721 aggttttcca caatcgcatc tagtacatcc cctgtaccga ttccatggac agatgagata
    12781 ggcagtggtt cacccaaacc gagagcatag aaatcataga tatcatttct catctcaggg
    12841 ttgtccacct tgttgactgc gaggataact ggtttgtggg tcttataaag cttacgagct
    12901 acgtattcgt ctgcatcagt aattccttcc ttaccagaca cgacaaaaac gataacatct
    12961 gcttcttcca tggcaatttc tgcctggtgc ttgatttgtt ccatgaaagg agcatcgaca
    13021 tcatcaattc ctcctgtatc aatcatacta aaagagcgat tgagccactc acccgttgca
    13081 tagatacggt cacgtgtcac tccttcgaca tcttctacaa tggagattcg ctcaccagcg
    13141 atccgattaa atagggttga tttcccaaca ttgggacgtc ctacaatggc aatagttggt
    13201 agggccataa tttctcactt tctacaataa cttcttctgt ttaagatttt ttctagttga
    13261 gcttggttct gcttggccaa actgttctgc tagacgctga ctccagcttg tggtcgcacg
    13321 cgctccagca tagtcagcct gaacacggtc ataagcttgg attgcctcag ttgactgttc
    13381 ttggtattct tcctcaaaga caacattctc tagtggcagt ctcggtttca tatcatgatg
    13441 ttgatttggc acacccagtg ccatcccaaa gacagaatag gtgtagtcag gtaggttaaa
    13501 gagctctgcc acttcttcag acttgtatcg aaccaaaccg ataatcacac caccatagcc
    13561 caagctttca gctgccaaca aggcgttttg tccagcaaga gctgcatcga ccgaactaat
    13621 caagagacct tccacacctt ggggttggaa ggtgtcggta tgaagtcggg ctcccttttc
    13681 tgctcggttc aaatctccga caaagagaag gaaaacagca gactggcgaa tggcttcttg
    13741 aggtaccaat tcatacaagg catctttctt ctcttgactt cgtaccacaa tcacagagta
    13801 ggattggaaa ttcttccaag atgatgccat ctgggctgct gtcaaaatct catttaagtc
    13861 tacttgggga atttcttgct ctttaaacct gcgcactgaa gtatgagcct tcatcaattt
    13921 aatggtttct gtcatcgacg gtttactcct tctaaacgag tctcctcagc caaataacgg
    13981 atgcgttcca tgacacgtct ggcttcccag gtttcgtcat ttccattttt ccctttagcg
    14041 aaatgcttct ccaaatcttc aaagttgaag ttagaggtga aaaaggtcgg taaattttcc
    14101 tgcatccgat attggagaat gacctgcagg atttcatcac gcacccaagc ggtggattgc
    14161 tcggcaccaa tatcatctaa aatcaggact tcagaaagct taatctcatc cactaaggtc
    14221 ttaacattgc catcaccgat agcatttttg acatcaatga caaagctagg atagtggagg
    14281 agagtggatg atacaccacg tttttctgat aaatcatgag ctagggcagc caccatgaaa
    14341 cttttaccca caccaaagtc tccatataag taaagacctt tcaaattatt ggggtaatcg
    14401 ttaacaaatt ctatcattct ttttagaaca gttaagcgct gaacatcatc acgataaaca
    14461 tctaaaaaac tgacattttt caggctagat ggaaaattaa ttaagttgag acgtttcttg
    14521 atagccgctt ctttttcagc tgcgattagt tcaggagttt cttcataaga aacatccgca
    14581 tagccatggt tcatgactaa tataggcttg tagcctttgg caatataatc tgtatctcct
    14641 cggaggaatt tatctctctc agtgatgtat tggttaaact tggaaatact acggttcaac
    14701 tcgtcctgat tgagggattc ttgctggaca aaggccgcaa catcaggatc cttcatgatt
    14761 ttctgaacta aatcttgata gtgaaaacga cttggttgac gtttgagtac atctccgaca
    14821 ctttccatct aatcacctcc gttatctaat tttgctaata attctagggt ttggcgttcc
    14881 atctcttcta attcctcagc ggatgacgta tttttatatt caggattact ccatttagga
    14941 atattggttt ttgctggggc agtctgattc tgtttttgtg tttttgtttt ctgccctcgc
    15001 tcacggatgc gcaagactgc cttttctgcc gaatgaatct tttgataggc atagtcattg
    15061 gctaccttca tggcatattt ctcattgata tttgccgaat cgaccttatt aaaggtcaat
    15121 aaaagaatga tattgatgac ttcgtccagc aagcccaagc cagccatctg ttgcaagagt
    15181 tctctttctg tttgggtaat ggttcccttg cgtgtttgct tgatttctgc caagaactgc
    15241 agggcagttt tacttttggc ttctttgata atggttgttt ccttaagact aaagtcagag
    15301 gaaactggtt tttgagcaat tttttcacgc atgcgtttgg ttgaaataac ctgagaaaca
    15361 gctgttgact tggccaattg ataggtttca aaccaagtcc atttcttctc ctcggcaata
    15421 gcaaagaggt ttaagacatc ggactgctca tccgcaaaac gaagtccatc tcgagccatc
    15481 agctggcgaa aatgttccaa gtcaaaatca ttggccactt tcttcttgag accaaggtct
    15541 tcttgactgc ctagttctgc caattctgga aagacttgat tgagtgagac aggtatttct
    15601 tcaccatcag cactttcaac tttcaaatcc tccacagcag agtcgccaat ctttttctct
    15661 aagagtctgc gataaacagg atgctccaag aagtcttgac tagatagagg agcatggagg
    15721 gctagctgat aaacatcccc cttttgatag agggtcaaga gattaaaagc agataagatt
    15781 ttcaatgatt ttatcagtct atccatccca aagttgagat gattgaggat acttgaaaaa
    15841 agatattcct ttctaccatt atcccaaaaa ctgattgtat aaagataaag gctcagtgcc
    15901 tcctgaccga taatcgggag gtagcactgt accagagatg aggtatcttg cgacacccga
    15961 ttattcttta gataagaaaa acggtcaatt ggcttcattt atctttcctt tttcttttta
    16021 gaggactggg tgatttgttg gagcaagctc tctaactcac tgacatcctt aaaactacga
    16081 tagacactag caaaacgtac ataggtaatc tcgtccaatt cagccaactc ctccatgaca
    16141 agtgaaccaa tgtcctcact ttgaatttca ttttcatttc gaccacggag tttctgttcg
    16201 atacgattga ctaccatgtt gatttcatca cttgacacag gacgtttctg ggctgagcgg
    16261 ataatcccat taaagatttt atctctggag aattgttccc gtgtgccatc ttttttaaca
    16321 accactaagg ttctttcttc tactcgttcg taggttgtaa aacggtgttg gcactcgtcg
    16381 cactctcgtc ttctacgaat ggtgttccct tcttctgctt ggcgactatc gataacactt
    16441 gacttggtag ccccacattt tggacaacgc atcctttccc tccttatcgt tttcttttca
    16501 ttataccatt ttttaagcga ttcccaaaac aattcttctt tttgcttgac aagttttttg
    16561 ttttgttgta ttatttaatt aagacaaaag gataagagaa aggagactaa gatgtcctgg
    16621 acatttgaca acaaaaaacc catctattta cagattatgg agaaaatcaa gcttcagatt
    16681 gtttcccata cactggaacc caatcaacaa cttccaaccg tgagggagct agctagcgag
    16741 gctggtgtca atcccaatac catccaaaga gccttatcag accttgaacg agaaggattt
    16801 gtctacagca agcgaacaac tggacgattt gtgactaagg ataaggagct aatcgctcag
    16861 tcacgcaaac aattatcaga agaagaattg gaacacttcg tttcctccat gacccatttt
    16921 ggctatgaaa aagaagaact accaggcgta gtcagtgatt atattaaagg agtttaagcc
    16981 tatgtcatta ctagcatttg aaaatgtatc caaatcatat ggagcaacac cagcccttga
    17041 aaatgtttct cttgacattc cagctggaaa aattgtcggc cttcttgggc caaacggctc
    17101 aggaaaaaca accctgatta aactaattaa tggcctctta caaccagatc aaggacgtgt
    17161 cctcatcaac gacatggacc caagcccagc aaccaaggcc gttgtagctt atttgcctga
    17221 tacgacctat ctcaatgagc aaatgaaggt caaagaagcc ctaacctact tcaagacctt
    17281 ctataaagat ttcaatcttg aacgcgctca tcatctactt gcagacctgg gcattgatga
    17341 aaatagtcgt ctcaagaaac tatcaaaagg aaacaaagaa aaggttcaac tgattttggt
    17401 tatgagccgt gatgctcgtc tctatgtttt ggatgaaccc attggtgggg tggatccagc
    17461 agcccgtgct tatatcctca ataccattat caacaactac tcaccaactt ctaccgtttt
    17521 gatttctacc cacttgattt ctgatatcga gccaatcttg gatgaaattg tcttcctaaa
    17581 agacggaaaa gtcgtccgtc aaggaaatgt agatgatatt cgctacgagt caggtgaatc
    17641 cattgaccaa ctcttccgtc aggaatttaa ggcctaagca aaggagatta tttatgtttt
    17701 ggaatttagt tcactacgaa tttaaaaatg ttaacaagtg gtatttagcc ctctacgcag
    17761 ccgtgctagt cctttctgcc ctcatcggaa tacagacaca aggctttaaa aatctacctt
    17821 accaagaaag tcaggctact atgctacttt ttctagctac agtctttggt ggcttgatgc
    17881 ttacacttgc gatttcaacc attttcttga ttattaaacg cttcaaaggt agtgtctacg
    17941 accgacaagg ctatctgact ttgaccttgc cagtttctga acaccatatc atcacagcca
    18001 aactaatcgg tgcctttatc tggtcattga ttagcaccgc tgtattggct ctaagtgctg
    18061 ttattattct ggctttaaca gctccagaat ggattcctct ttcttatgtg attacatttg
    18121 tagaaacaca tctccctcag atctttctta caggtatatc cttcctacta aataccattt
    18181 caggaatcct ctgcatctac ctggctattt ccattggaca gcttttcaat gaataccgta
    18241 cagcactcgc tgttgcagcc tacattggta tccaaatcgt cattggattt attgaacttt
    18301 tcttcaatct tagttccaat ttctatgtca attcactggt aggactcaat gaccatttct
    18361 atatgggagc aggtatagcc attgttaaag aactcatatt catagctatc ttttatctcg
    18421 gaacctacta catcttgaga aataaggtta atttgcttta aataattttt acctagatat
    18481 gtaacatact catagaacaa aagagaccag gcaaaaagtc tttaaaatta gaaaacgcat
    18541 agtatcaagt gttaaaaatc cttgatatta tgcgtttttt gtgagctgac ttatttcctt
    18601 tcgctatatc gcaaaatgaa ataagaacgg aacgatggga ttttggaatt caaatcaatt
    18661 tataagaatg ttttagaagt aatattatcc tattccagat tcagttcact atacaattga
    18721 gttttcaagc aacctgttta cataatgtgt acataattag gttcgtgatt ccaccctttt
    18781 cacctttaaa aacctcgctt tcgcaaggct cttctattta taagataagg cacgtttaaa
    18841 ggttttccaa atccctaaat catccgtttg aagaacgaga ctagcataca tgcgtccgat
    18901 aaatcctgtt gctaccaccg caaaaatcac tgtaatagca agtgaaatcc atgcttccgc
    18961 tccctccgca tagccattaa tcgttcgaaa cggcataaag aaggtcgaaa taaagggaat
    19021 ataagaacca atcttcaaga ggagattgtc accagctgca cctagagctg tcactccaaa
    19081 aaaaccaccc ataatcaaaa tcatcaaagg cgacaaggct ttccctgagt cctcaggacg
    19141 agaaaccata gatcctagga aggctgccaa gactacgtac atgaaaagac tgatcaaaat
    19201 aaagagcagg gtattcagtg agatagcatc tcccaagtga tccaaaatac cagactgagc
    19261 caagaatggc aaatctttaa agagcaaaac ggcagccaga ccacctacaa catagatccc
    19321 aatatgcgtt aaaatcacta gaaacagagc catcatccgc gcatagaaat agtgacttgc
    19381 ccttatgcta gaaaagacga cttccataat tttggtgcct ttttcactgg caacttcctg
    19441 agctgttaca cccgcatagg taatcagaat catataaaga aagaatccta aggcacctgc
    19501 tgcaattgtt tgaataaact ttttattttc cttggcttca tcaatctttt ctgtgaattg
    19561 aattgtctgc gctaagcgtt tttcctgctc ttgagacaag gaagcagttg aacgattaag
    19621 ctgattttgc agttcattga gtgtacctgt aacctcaaat ttaattccat tttcaagcga
    19681 tgtttcgcca tgataaactg cctttagaac actatcttct tgatcaatgg tcaaataacc
    19741 ttttaatttt tcttctttaa ttgcttcttt ggcacttgct tcatctttat agtcgaagtt
    19801 aacaccattt acattcttca gtccttctgc tacagatggc actgttgtca ctactgccac
    19861 tttattattt ttagccatag aagaaccttg gagatgccca attcctacag agattcctaa
    19921 aaagaggaac ggcgaaatca ccataaagaa gaaactccat gactcgacat gtcgaagata
    19981 ggtttccttg attacaaccc acatatttct catacttcca ctcctgattc tagtttaaag
    20041 atttcatcga tagttggcgc ttgttggtca aatgttgcga tatattgacc ttgagtcaag
    20101 attgggaaga gttcccttcc agcgctctca tcctccaaaa tcaatttcca actgccttgt
    20161 ttggtcaagc tcacctgttt gacatgagga agattttcca attcttcctt gcttcgttca
    20221 cttgaaacaa agagacgcgt tttcccgtat tgattgcgga catcctgaac tggtccgtgc
    20281 aagaccacac ggccatctcg gatcatcaga atatcgtcac aaagttcctc aacattggtc
    20341 atgacatggt cagaaaagat aatggttgct ccgcgctctt tttcctgaaa aatgacttgt
    20401 ttgagcaatt ctgtattaac tgggtccaat ccactaaaag gctcatccaa gataatcagg
    20461 tctggttcat gaatcagagt aataatgagc tgaatcttct gctgatttcc ttttgacaga
    20521 ctcttgattt tatctgtcag ctttcctttc acttccaacc tcttcatcca ttgagggagt
    20581 ttttctttga cttctttggc atccatgcct tttagagtcg ccaagtagcg aacttgttca
    20641 agaactgtca atttaggcat gagactgcgt tcttcaggca gataaccaat ccgagcatag
    20701 gtctcctgac gaatatcctg accatccaga ccgatttctc cctgatattc taggaatttc
    20761 aaaatactat ggaaaatcgt tgtttttcca gcaccatttt ttccgactag tcccaaaata
    20821 cgacctggtc gcgcttgaaa gtcaatacca aacaaaactt gcttggagcc aaaacttttc
    20881 tctagacttc ttacttctag catctttcac ctccgaaatt tcttgcactc attatactcc
    20941 tttttgatag cctttacaat gtttttgtcc atttttagaa gactattgct gtgtaaaata
    21001 tggcctggag cacttttata ctcaatgaaa agcaaagagc aaactaggaa gctagccgta
    21061 ggctgctcaa agtacagctt tgaggttgca gataaaactg acgaagtcag ctcaaaacac
    21121 tgttttgagg ttgtggatag aactgacgaa gtcagtaact atatctacgg caaggcgaag
    21181 ctgacgtggt ttgaagagat tttcgaagag tattagtgat aaatccatta tacagtagca
    21241 aacttaattt ataccttccg ctcctcaact gtctattttt aatcctgaat tgttatttga
    21301 gtaactcctt tttcctcata aagttttctt cctctaaaac ttctggaaaa aagcgaatag
    21361 tttcagacaa catttttata agaaacaagt tcatctgtca tttcaagaag gagtaatcct
    21421 ttatctacta atggacggaa cggaattcaa ccgcttgtcc gatatgtttt ctaaggatta
    21481 tatagcaaaa tgaaataaaa acaggacaaa tagatcggga cagtcaaatc gatttctaac
    21541 aatgttttag aagtagatgc gtactattct agtttcaatc tattatatct attatgcaca
    21601 ccactatagg atctaataaa aatcacaaca agttcattca tagatggtta cctcagggaa
    21661 ctaagaaaac gactacaaag gaagtcgcat tcatcgaaaa gtggattaac aactatccta
    21721 aaaaatgctt gaactacaag tcccccagag aagacttctg gatgactaac ttgaacttga
    21781 aatttagcaa taattaattc accatctaac tatatttagt aattatttca gaactgatta
    21841 atattaaaat taactaacaa ttcaaaggat tcatactagc cataaattac gtccatcaga
    21901 gagagactct tactactttt agattttagt ctttctagct tcagaataca tctaaacttt
    21961 agggaaaatg actattcgaa agcgcgaatg cctcaaaatt atctcagata agctattcga
    22021 aacttagaat gcttttaaat tcatggaatt gcgattattc gaaacctaga atgcatataa
    22081 cctttagttg acagacctat tctaagtctc gaagggctat ttactttcta ttccttatca
    22141 aaaaagactc attccccctt tctcctccaa aatatggtat agtagaaata tactatctat
    22201 gaggagttta catgtcacag gataaacaaa tgaaagctgt ttctcccctt ctgcagcgag
    22261 ttatcaatat ctcatcgatt gtcggtgggg ttgggagttt gattttctgt atttgggctt
    22321 atcaggctgg gattttacaa tccaaggaaa ccctctctgc ctttatccag caggcaggca
    22381 tctggggtcc acctctcttt atctttttac agattttaca gactgtcgtc cctatcattc
    22441 caggggcctt gacctcggtg gctggggtct ttatctacgg gcacatcatc gggactatct
    22501 acaactatat cggcatcgtg attggctgtg ccattatctt ttatctagtg cgcctatacg
    22561 gagctgcctt tgtccagtct gtcgtcagca agcgcaccta cgacaagtac atcggctggc
    22621 tagataaggg caatcgtttt gaccgcttct ttatttttat gatgatttgg cccattagcc
    22681 cagctgactt tctctgtatg ctggctgccc tgaccaagat gagtttcaag cgctacatga
    22741 ccatcatcat tctgaccaaa ccctttaccc tcgtggttta tacctacggt ttgacctata
    22801 ttattgactt tttctggcaa atgctttgac acgtaaaaaa tccgtttggt ttcccaagtg
    22861 gattttgtgc tttattttga aacttctttt gcaagaacaa agttcccaag tgtggcagaa
    22921 ccatttcctg cgactgctgg cgtcacgata tagtcacgca catctggtac tggtaggtaa
    22981 ccattaagaa gagatgtaaa tttctcacgg acacggtcca gcatatgttg ttgagccatg
    23041 acccctccac caaagacaat cacgtctggg cggaaagtca ctgtcgcatt aaccgcagct
    23101 tgagcgatat agtaggcttg aacatcccaa acagggttgt tgagttcaat agtttcccca
    23161 cgtacacctg tacgagcttc caaacttgga ccagctgcat aaccttctag acatccctta
    23221 tggaaaggac aaacaccctt aaactctttt tcaatatcca ttgggtgtct agcaacataa
    23281 taatgaccca tttcagggtg acccacacca ccgataaact caccacgttg gatgacgcct
    23341 gcaccgatac ctgtaccgat tgtgtagtaa accaagtttt cgatacgacc accagcattg
    23401 ttacgggcaa ccatttcacc gtaagcagag ctgtttacgt ctgttgtgaa gtacattggc
    23461 acgtttaggg cgcgacgaag ggcaccaagc aagtctacat ttgcccagtt tggttttgga
    23521 gtcgtcgtga taaagccata agtttttgag tttttgtcaa tatcaatcgg cccaaatgaa
    23581 ccaactgcaa gaccagcaag gttatcgaat tttgagaaga actcaatggt tttatcgatt
    23641 gtttcgattg gagttgttgt tggaaattgt gttttttcta caacgttaaa gttttcatca
    23701 ccgacagcac agacaaactt tgtaccgccc gcttccaagc ttccatataa ttttgtcatg
    23761 ataaacctct tgtttttatt ttctttatta tagcatactt cgaaagtcta aatgtctcta
    23821 ttttttagat tttcctctgt aaatcttact atctaataaa aacgaacaaa catgtcattt
    23881 gttcgttttc acattagaga ggattgatta gattttcact tcgatcacag catccccctt
    23941 cgaaactgaa cctgttgcga ctggagctac tgaagcgtag tcagctgtat ttgtaacgat
    24001 aaccattgtt gtatcatcaa gtccagctgc agcgattttg tttgagtcaa atgttccaag
    24061 aacatcgcca gctttcacct tattaccttg agcaactttt gcttcaaaac cgtcaccgtt
    24121 catagataca gtgtcaatac caacgtgaat caaaacttca gcaccatttc ttgttttcaa
    24181 accaaaagcg tgccctgttg gaaaggcaat tgaaacttca gcatcagcta gtgcatagac
    24241 cacgccttga cttggtttca cagcgatacc ttgtcccata gctccacttg agaagactgg
    24301 gtcattgaca tcagcaagag cgacaacatc accgacgata ggagttacaa gtgtttcatt
    24361 ttgaagagct gctggcgcaa cttcttcttt ttcttcagcc acttcagctt gttttgcagc
    24421 tgcagttgcg tctacttcat cttcgtaacc aaacatgtaa gtaagagcaa aaccaagggc
    24481 aaatgataca gctaccataa gaaggtattg tggaagttgt ccgttaccaa cataaagcat
    24541 tgtaccaggg atgatggtga taccattacc agtaccagca agtccaagga tagaagccaa
    24601 tccaccaccg attgcaccag caatcaatga aaggaagaat ggtttacgga agcgcaagtt
    24661 caccccgaag atagcaggct ctgtaatacc taggaaggca gaaagagcag ccgggaaagc
    24721 aagtgttttc agttttggat tttttgtttt aacaccaacc gcaacagtag cagcaccttg
    24781 agctgtcata gcagctgtga tgatagcgtt gaatgggtta gcatggtcag cagcaagtaa
    24841 ttgcacttca agcaagttga agatgtggtg cacacctgac acgacgatca attggtgaac
    24901 cccaccaatc aagaaaccac caagaccaaa tggcatgcta agaatcgctt ttgtagcaat
    24961 aaggatgtag ttttcaacaa cgtggaaaac tggtccaata acaaagagtc caaggataga
    25021 catgaccaaa agtgtcacga atggtgttac caagaggtca atgacatctg gaacaacctt
    25081 gcggacagct ttttcaaatt tagctccgac aaccccgatg atgaaggctg gaagaacgga
    25141 accttgcaaa ccaacaacag ggatgaaacc aaagaagttc atcgctgtta cttcaccacc
    25201 ttgagcaact gcccaagcgt ttggaagtga gccagagaca agcatcatac caagaacgat
    25261 accaacggca ggatttccac caaatacacg gaaggttgac cacacaacca aacctggcaa
    25321 gatgatgaag gctgtatctg tcaagatttg tgtgtaagtt gcaaagtcac ctggaagtgg
    25381 catttcaaga gcgttgaaaa gaccacgcac acccatgaag agacctgtcg ctacgataac
    25441 tgggatgatt ggaacgaaaa catcaccgaa agtacggata gcacgttgga accagttccc
    25501 ttgtttagca acttctgctt tcatgtcatc cttagatgat gttggtaagc caagtacaac
    25561 aacttcatcg tacattttgt taactgtacc tgtaccaaag ataatttggt attgccctga
    25621 gttaaagaaa gcaccttgaa ctttttccaa gttctcaatc acttctttat tgattttctc
    25681 ttcatctttg accatgacac gtagacgagt cgcacagtgg gcaacactat tgacattttc
    25741 acgtccgccc aaggcatcga tgactttttt tgcaatttcc tgattgttca tttgcaaaaa
    25801 tctccttata taacattttg ttcttgtttg aaagcgattt tattcgccct tacgactatt
    25861 attttatcat gttttaaaaa tatgtcaagc gttttgcaga aaaaatattc tatccactta
    25921 gtgggcaagt tttagattga ttgtttttga ctgtttcatc aggaattcct tgaaaaataa
    25981 gtttgaaacc ttggttaaaa agtattttat ttcattatct ttcacatttt cgtaaaaatt
    26041 tgattgattt cctgtattta tttcatgata atcgtttgac agttttttct attttttaat
    26101 ataaaaggct tgcatttttt atcgaaaaca gttactatta aaagtgataa gatttttgga
    26161 ggaatgaatg gaatggacaa ctgagcgtcg ttacagactt tatcaagatt ggacgcaaga
    26221 agaaattcaa catataaagg aaaatatggc acaatctcca tggcatactc attaccatgt
    26281 tgagccaaaa acaggacttc tcaacgaccc aaatggcttt tcttactttg atggcaagtg
    26341 gatcctcttt taccagaatt ttccttttgg tgcagcccac ggtttaaaat cttgggcaca
    26401 gctagaaagt gatgatttgg ttcactttag agaaactgga gtcaaagttt tgccagatac
    26461 tccattagat agtcacggtg cctactctgg ttctgccatg caatttggcg ataacttatt
    26521 cctattttat acaggaaatg ttcgcgatga aaactggatc cgtcacccat accaaatcgg
    26581 tgctttgatg gacaaggagg gtaagattac aaagattgac aagatcttga ttgaccagcc
    26641 agcagactct actgaccact tccgcgatcc acaaattttt aactttcagg gtcaatatta
    26701 tgccattgtc ggcggacaag acttggagaa aaaaggtttc gttcgtctct acaaggctgt
    26761 caataacgac tacacaaact ggcaagcagt tggcaacctt gactttgcta acgaccgtac
    26821 tgcctacatg atggaatgtc ctaatctggt ctttgtagag gaacagcctg tccttctcta
    26881 ctgtccacaa ggattggata agaaagttct agactacgat aatatctttc caaatatgta
    26941 taagattggg gcttcctttg accctaaaaa tgccaaaatg gtagatgtgt ctcaacttca
    27001 aaacatggat tacggtttcg aagcctatgc aactcaagcc ttcaacgctc ctgatgggcg
    27061 tgctctagca gttagctggc ttggtttgcc agatgtttct tacccatctg accgttttga
    27121 ccaccaagga accttctctt tggtcaagga actcactatc aaagacgaca agctctacca
    27181 gtatccagtc gctgctatta aggaccttcg tgcttctgaa gaagccttct caaaccgttc
    27241 ccaaaccaag aacacttacg aacttgaact caacttggaa gccaatagcc agagcgagat
    27301 tgtcttactt gctgataaag aaggcaaggg actttcaatc aactttgacc ttgtaaacgg
    27361 tcaagtgaca gtggatcgta gccatgctgg agaacagtat gcccaagaat ttgggacaac
    27421 tcgttcttgc cctatcgaga atcaggctac tactgctaca atcttcatcg ataactctgt
    27481 ctttgaaatt ttcatcaata aaggagaaaa agtattttct ggtcgtgtct tcccacatgc
    27541 ggaccaaaat ggtatcctga tcaaatctgg aaacccaact ggaacttact atgaattaga
    27601 ttatggtcgc aaaactaact gatgtcgcca aacttgcagg cgtcagtcct actaccgttt
    27661 ctcgggttat caataaaaaa ggatatctat ctgagaaaac catccaaaaa gtcaatgaag
    27721 ccatgagaga attaggctat aaacccaaca acctggctcg tagtctgcaa ggaaaatcag
    27781 ctaagttaat cggcttgatt ttccccaata tttccaatgt tttctatgca gaattgattg
    27841 ataaattgga acaccaactc ttcaaaaatg gttacaagac catcatctgc aacagtgaac
    27901 atgattctga gaaggaacgt gaatacatcg aaatgttgga agccaatcag gtggacggca
    27961 tcatttctgg tagtcacaac ctaggaatcg aagactacaa tcgtgtgaca gcgccgatta
    28021 tttcctttga ccgaaaccta tcgccagaca tccctgtcgt ctcctctgac aactatgctg
    28081 gtggggttct tgctgcccaa accttggtca agacaggtgc ccagtctatc atcatgatta
    28141 cagggaatga caattctaat tcgccaaccg gactgcgcca cgctggtttt gcatccgtac
    28201 tcccaaaagc tcctattatc aatgtttcca gtgacttttc tcccgtcaga aaagaaatgg
    28261 aaatcaagaa tatcttgacc cgggaaaaac cagatgccat ttttgcttcg gatgatttga
    28321 cagctattct ggtcattaaa atcgctcaag aattgggcat ttctgtccca aaagagctca
    28381 aggtcatcgg ctatgatggg acctacttta tcgaaaatta ctaccctcaa ttggctacta
    28441 tcaagcaacc tttggaagag attgcttgtc tcactattga tcttctcttg caaaagattg
    28501 aaggcaagga agtcgccaca actggttact tcttaccagt tacgctatta ccaggaaaaa
    28561 gtatttaaac acaagaaaac tcagaccgat tcgtctgagt ttttatgatc ttaaattttc
    28621 gagatagcgc tgggctgtct ctaggttaaa ggttttatct gcgataagct gctcgactag
    28681 gggagcaact tcagattcac tagccccagc taggagagct agggatttgg cctgtagttt
    28741 catgtggcct tgctggatgc ccgtacttac caaggctttg agggctgcaa aattttgagc
    28801 aagaccgatg gacacgataa tctgggctaa ttctctggca gaaggatttc ctagtagatc
    28861 atgactgaga actacacgtg ggttgaggcc gatagagcca cccttagtcg ctacaggcat
    28921 gggcagggtc atctcaccga ccaattcttc tctttcaagg tccagcgtcc agcaactaag
    28981 accttgataa cgtccatctc gactggcaaa ggcatgggcc ccagcttcga tggcacgcca
    29041 gtcattacca gtggcaatca aaatcgcatc aataccatta aaaattcctt tattatgagt
    29101 agcagctcgg taaggatcag cctgcgcaaa ctgactagcc aacgcaattt tctccgcaat
    29161 ctctcgtcct tgatcctttt ggcggctcaa gtagcgaaag gcgatgcgac agcttgcagt
    29221 caccagagaa tcggtcgcgt agttggacag gattgccatg agactctgtc cctgactgag
    29281 ttcttctaag actggtttca aggcttccag catggtgttg agcatattgg cacccatggc
    29341 ttcctgggta tcgacatgaa tataaacaac gagaaagtct ggttcacctt ttatctgctc
    29401 gacatgcaga tcacgcgccc cacctccacg tttaacgata gaaggatagg cttgattggc
    29461 aagctccaag agctccgctt tcttgctggc aatcttctct tgcgctagtt taggattagc
    29521 aacttgataa agggctacct gcccaatcat ctgtcgctga tggacttgtg cagtaaaacc
    29581 acctgcacgc ttgatgattt tgctggcata gctggccgcc gcaaccacag agggttcttc
    29641 tgtcacatag ggaacggtgt attcctgacc gttgacaagt acctccggaa ccagtgaata
    29701 aggcagagaa aaagttccca ctacattctc actcagctgg tctgccacag tcacgctcat
    29761 ctgttcatcc ttctccagac tagcttgtct ctcaggacta aggagcgcct gagcttttaa
    29821 cagctcgagg cgctcttggt atgatttttt agaaaatcca ttccaactta tcttcattat
    29881 ttttcaacct tgctataacg gcgttggtgg tcgagaattt caaccaaggc aaaatcttga
    29941 ttttcatagc cagcaaactg ggcagagttt gtttcatcca agtttacttc ctcaaaaaag
    30001 accttttcat agtctgcaac ggatagggca gttcgttggt tgagcttgtt caagcggtct
    30061 ttatccaaat aagcttcata tccttcaacc aattcaccac tgaagaactc agccacagct
    30121 ccacttccgt aactataaag ggcgatttta tccccagctt tcaagctatc tgtattttcc
    30181 aagagagaca aaagtccaag gaaaagtgaa cctgtgtaga tattccccac cttttgactg
    30241 tagagaatag actggtcaaa atgcttttgt aagaggtctt ttttctcttg aggcaggctc
    30301 ttatccatga tttttttcaa gccttttagc gctaatttag gataaggcaa gtggaaacaa
    30361 acagccgcaa aatcatccaa agtaagctgg tagcgttttt gatattcaag ccaagtcgtt
    30421 ttcaaactat ccaagtattg ttgggtagaa tagacaccat ttacataagg agttgtcgag
    30481 taatttggtc gccagaaatc catgatgtca cgggtctgag ctacattgtc attattaaag
    30541 gccatcatgc gtggattttg tgtaatcaac atagctacac ttccagcacc ttgagttggt
    30601 tctcctggag tttcaatacc gtatttggca atatcactgg caatgaccaa gaccttggac
    30661 tccggagaat tttccacatg caatttggca taatggaggg cagcagtcgc tccgtagcag
    30721 gcttctttaa tctcgaaact acgagcaaag ggctggatgc ccagcaagcc atgcacaaag
    30781 acggccgcag ccttactctg gtcaattcct gactcggtcg ccacaatgac catgtcaact
    30841 tcttgtcttt cttgctcagt taaaatagag tcactagcac tggccgccaa ggtcacgata
    30901 tcctcagtta ggggcgcaat actcaattcc ttgagtaaga gtcctttact taatttttca
    30961 gggtcaattc ccctcgcttc tgctaagtct tgtaatttca agacatattg actggtcgca
    31021 aaaccaatct tatcaatacc gattgtcata tttacctctg ttttatcatt catgtaaaaa
    31081 atcgttctat actattttat cacaaatggc agtaaaagag agaaaaaaga cttgattcac
    31141 caaatcaagc ctcttattgg tcatcatttt aaagaatgat tagttgctag agagttcacc
    31201 gatataagta gctttataag ctccattcac agttatcagc tcctggagga tcaaatttcc
    31261 tgagtaagtc cttcccatct catctacaaa tttttgataa aactgactgg tcggaatttc
    31321 tctgacatcc ttatcaaatg tcttatcaag tgttttacta accttctcag caatcaattg
    31381 atgctcttgc catccacttt gaaactctga gcccgaacta gaaaccatga ctgggataaa
    31441 caacaaggtc agtagactta cagacaataa ggaaaatagt agacttcctg caaaactaga
    31501 atcctagttc atgattgata ataacagcaa tcaaattcat tcgtaatccg aagcgtttac
    31561 gatgatttcg ataggttgtt gaaaacattt taaacgt
//
LOCUS       DBEROT010000027        30744 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.27, whole genome shotgun sequence.
ACCESSION   DBEROT010000027 DBEROT010000000
VERSION     DBEROT010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 30744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30744
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.27"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..555)
                     /gene="mobQ"
                     /locus_tag="ACL8CG_001365"
     CDS             complement(<1..555)
                     /gene="mobQ"
                     /locus_tag="ACL8CG_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HGS1343952.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDPQLFTPNLKTIQNPCLSLDPG"
     gene            complement(869..1186)
                     /locus_tag="ACL8CG_001366"
     CDS             complement(869..1186)
                     /locus_tag="ACL8CG_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGS1343953.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            complement(1242..1721)
                     /locus_tag="ACL8CG_001367"
     CDS             complement(1242..1721)
                     /locus_tag="ACL8CG_001367"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1343954.1"
                     /translation="MFITEKKGKSSQVPTGSSIPKRYLLDGKTPRISATNIDNGILGY
                     YEDIDDKNYRVFENFISVSFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSI
                     IRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(1720..1904)
                     /locus_tag="ACL8CG_001368"
                     /pseudo
     CDS             complement(1720..1904)
                     /locus_tag="ACL8CG_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(2055..2849)
                     /locus_tag="ACL8CG_001369"
     CDS             complement(2055..2849)
                     /locus_tag="ACL8CG_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343955.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(2849..3856)
                     /locus_tag="ACL8CG_001370"
     CDS             complement(2849..3856)
                     /locus_tag="ACL8CG_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGS1343956.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQTVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(3856..4863)
                     /locus_tag="ACL8CG_001371"
     CDS             complement(3856..4863)
                     /locus_tag="ACL8CG_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGS1343957.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(4853..5878)
                     /locus_tag="ACL8CG_001372"
     CDS             complement(4853..5878)
                     /locus_tag="ACL8CG_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS1343958.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(6271..6489)
                     /locus_tag="ACL8CG_001373"
     CDS             complement(6271..6489)
                     /locus_tag="ACL8CG_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1343959.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(6735..7013)
                     /locus_tag="ACL8CG_001374"
     CDS             complement(6735..7013)
                     /locus_tag="ACL8CG_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343960.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAVYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(7227..8858)
                     /gene="rlmD"
                     /locus_tag="ACL8CG_001375"
     CDS             complement(7227..8858)
                     /gene="rlmD"
                     /locus_tag="ACL8CG_001375"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS1343961.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLIRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFVELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(8932..9906)
                     /locus_tag="ACL8CG_001376"
     CDS             complement(8932..9906)
                     /locus_tag="ACL8CG_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGS1343962.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(9980..10594)
                     /gene="pmp23"
                     /locus_tag="ACL8CG_001377"
     CDS             complement(9980..10594)
                     /gene="pmp23"
                     /locus_tag="ACL8CG_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGS1343963.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNVSSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(10594..11568)
                     /locus_tag="ACL8CG_001378"
     CDS             complement(10594..11568)
                     /locus_tag="ACL8CG_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGS1343964.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(11576..12832)
                     /gene="glyA"
                     /locus_tag="ACL8CG_001379"
     CDS             complement(11576..12832)
                     /gene="glyA"
                     /locus_tag="ACL8CG_001379"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGS1343965.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(12894..13325)
                     /locus_tag="ACL8CG_001380"
     CDS             complement(12894..13325)
                     /locus_tag="ACL8CG_001380"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1343966.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(13327..13929)
                     /locus_tag="ACL8CG_001381"
     CDS             complement(13327..13929)
                     /locus_tag="ACL8CG_001381"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGS1343967.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(13913..14752)
                     /gene="prmC"
                     /locus_tag="ACL8CG_001382"
     CDS             complement(13913..14752)
                     /gene="prmC"
                     /locus_tag="ACL8CG_001382"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGS1343968.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(14752..15831)
                     /gene="prfA"
                     /locus_tag="ACL8CG_001383"
     CDS             complement(14752..15831)
                     /gene="prfA"
                     /locus_tag="ACL8CG_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGS1343969.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(15828..16418)
                     /locus_tag="ACL8CG_001384"
     CDS             complement(15828..16418)
                     /locus_tag="ACL8CG_001384"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGS1343970.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            16541..16723
                     /locus_tag="ACL8CG_001385"
     CDS             16541..16723
                     /locus_tag="ACL8CG_001385"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGS1343971.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            16860..18233
                     /gene="mnmE"
                     /locus_tag="ACL8CG_001386"
     CDS             16860..18233
                     /gene="mnmE"
                     /locus_tag="ACL8CG_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGS1343972.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(18280..19215)
                     /gene="dapA"
                     /locus_tag="ACL8CG_001387"
     CDS             complement(18280..19215)
                     /gene="dapA"
                     /locus_tag="ACL8CG_001387"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGS1343973.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     YPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(19271..20347)
                     /locus_tag="ACL8CG_001388"
     CDS             complement(19271..20347)
                     /locus_tag="ACL8CG_001388"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGS1343974.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCGLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(20933..21005)
                     /locus_tag="ACL8CG_001389"
     tRNA            complement(20933..21005)
                     /locus_tag="ACL8CG_001389"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20970..20972),aa:Thr,seq:ggt)
     gene            complement(21105..21614)
                     /locus_tag="ACL8CG_001390"
     CDS             complement(21105..21614)
                     /locus_tag="ACL8CG_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGS1343975.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(21612..21708)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            21737..22168
                     /locus_tag="ACL8CG_001391"
     CDS             21737..22168
                     /locus_tag="ACL8CG_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGS1343976.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            22250..22627
                     /gene="mscL"
                     /locus_tag="ACL8CG_001392"
     CDS             22250..22627
                     /gene="mscL"
                     /locus_tag="ACL8CG_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGS1343977.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(22669..23763)
                     /gene="hemH"
                     /locus_tag="ACL8CG_001393"
     CDS             complement(22669..23763)
                     /gene="hemH"
                     /locus_tag="ACL8CG_001393"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGS1343978.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            23918..25141
                     /gene="pepT"
                     /locus_tag="ACL8CG_001394"
     CDS             23918..25141
                     /gene="pepT"
                     /locus_tag="ACL8CG_001394"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGS1343979.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTTIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25177..25830)
                     /locus_tag="ACL8CG_001395"
                     /pseudo
     CDS             complement(25177..25830)
                     /locus_tag="ACL8CG_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            25828..25992
                     /locus_tag="ACL8CG_001396"
                     /pseudo
     CDS             25828..25992
                     /locus_tag="ACL8CG_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(26069..26625)
                     /locus_tag="ACL8CG_001397"
                     /pseudo
     CDS             complement(26069..26625)
                     /locus_tag="ACL8CG_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672611.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(26732..27292)
                     /locus_tag="ACL8CG_001398"
                     /pseudo
     CDS             complement(26732..27292)
                     /locus_tag="ACL8CG_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672571.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27518..30106)
                     /locus_tag="ACL8CG_001399"
     CDS             complement(27518..30106)
                     /locus_tag="ACL8CG_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGS1343980.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTPSPSLPINPGTSHEKHEEDGYGFDANRIIAED
                     ESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSNAKE
                     MKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVGIGH
                     SHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVSFSF
                     PPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFKYTI
                     ASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDALVRV
                     FDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYIVEV
                     PILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTSNST
                     LEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTGEAP
                     QGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPEGNV
                     GSDPMLDSALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKKN
                     LSDLIA"
     gene            complement(30316..>30744)
                     /locus_tag="ACL8CG_001400"
     CDS             complement(30316..>30744)
                     /locus_tag="ACL8CG_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343981.1"
                     /translation="DHVRKNKADQDSKPDEDKEHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDEAEIPQVENSVINAKIADAEALLEKVTDPSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT         8907 a         6118 c         5320 g        10399 t
ORIGIN      
        1 tccaggatct aagctaaggc aaggattctg gatggttttt agatttgggg tgaataattg
       61 gggatctagg atatattctt tttttgactt ggctaagaac tctccttttt cgtttattgg
      121 tcgcattatg gtcattatat gacaatggat atttccattt ttatcttgac tctcatcatg
      181 aattgcataa tctactatca ttccttgtga tgttaaattt tcttttatat atctttcaac
      241 caggttttta ttttcactta aagataactc ttttggtagt cctattatga attgtcttgc
      301 tagttgtgca ttagaatttt tttctgccat ttctacttta ttccataagg tagacctatc
      361 attaaattct tttggtatat gatcaggcaa tattatattt tttactaata ttttttcttt
      421 tcttgtgtag tcatgggtta ctccgtccca ttcatttttt attttttctc cacttatata
      481 tgctgcactt gctactgcac ttttgccttt tcctcttgat attatgttta ctgaaaaatg
      541 aaaactgtct gccattttta tcacttcctt tctttctttg ttgttttagg tggaggctta
      601 atagtttttt tatatcctct ttgtgaatga gcgttttgaa atgatagaat aaaaaaagcc
      661 gactactgaa ttaatttttg ttgtttcagt atgtcggctt aattgttact ttcatttcaa
      721 attttaaaag tcaagggcga gccttagcga gtttatttac ccttgacttt taaaaagcga
      781 atggttgttg ctccctgcaa gggtttgact ccgcaggacg caagcaccct ttagggtgta
      841 taattgcgcc cttgtaacca agggacaatt atgttatttc atctttagat gatttttcta
      901 cattatcatc tattctttct tctaaaattt ccattatgtt taatcttatt tcttcatcat
      961 ttaacgtttt tattaactta taaaattcat cttttgttaa atcaatactt tcttcaaaaa
     1021 tactttcaaa cactgcacct ttttctataa gtcttttgtt tcttgctttt ctttcttgtt
     1081 cattaagttt tttcttcaac tgtctttttt gattttgtaa ttgcttaatg ctttcttctt
     1141 tcttttcaat ctgttcttca atacttaatc ttttacttgc catcatgtat cctttcttaa
     1201 aataaaaaac gactagattt ttatttctaa tcgttcttat tttaaatatt ataatttgct
     1261 atattgcatt ttaattttaa gtcttctata tatctttcca tgtaattcca atctggagta
     1321 cctctactgt ctatcggtaa tttaattttg atatctggca atactgtgct agatatttga
     1381 tctttatatt cagtattttt taaagcttgc ctaataattg aagttaaata gaatgctact
     1441 tctttattca attctttatt ttttaatttt aaacaatgaa ttttcatatc taggcttgct
     1501 ttatatttat gataaaagac tgctcctaaa aatgaaacag atataaaatt ttcaaaaact
     1561 ctataatttt tatcatctat atcttcgtag taacctaaga taccattgtc aatatttgta
     1621 gcactaattc taggagtttt tccatcgagt aaatatcttt ttggaataga tgagcctgtt
     1681 ggtacttgac tcgattttcc ctttttttcg gtaataaata tttcttttta ttttgttgtc
     1741 tgatattttt cctacctgtc ctttgtagga tgagtatttt ctagattttc ttgaataact
     1801 ttttacttga agttttagct tttgaactag tcgttgtact ttctttttgt ttattatcag
     1861 tcctgatctt tttaatattg ctgttattct ctatatccta tttttcattc atgatattct
     1921 tttactaatt ttatcttaaa ttctgtgctg tatttgccat taaaaaactg acctccttta
     1981 gttagttttt tggcctaact tttgagggtc agttcaaaat ttgcgacttt taaatgaatt
     2041 ccaatattca attattaaga gctaacatgg tgcttgccaa taggaatcat tagaggcgaa
     2101 ttggaaatag ggtcacgtat aatttttgct tcaagattaa agatatcttt aactagttta
     2161 tcatttagta tatcttcagg ctttccctct gcaacaagtt taccttcttt aattgcaaat
     2221 aggtaatcag cgtatcttgc tgttagattt atatcgtgca aaatcatgca aatggttgtc
     2281 ttatattttt ggtttagatc agtcaagagg tctaatagtt ctatttgata tgagatatcc
     2341 aagtaagtag ttggctcatc taaaagtagg atacttgtat cttgggctag ggctagagct
     2401 atccatactc tttgcctttg acccccagaa agttcttcaa ctaggttatt tgctagatct
     2461 tcaacattgg ccttaaccat tgatctgttt attatttcaa ggtcatcttt tccaagactc
     2521 ttaaaaggct ttctgtaggg gaaacgacca cggcttacaa gatcagctac tgttattgat
     2581 tcagggatta ttggagattg aggtaatata gctatgtgtt ttgctaaatc tttttcttta
     2641 taagaattaa ttgatttatt atcaagcaat acttctccct ctaatggctt tataagtcga
     2701 gacaaggttt taatgagtgt tgatttccca caaccatttg acccaataat aactgatatt
     2761 ttttcttcag gtatttttat atttatattt tccaagatta ttttttcatc ataaccgcag
     2821 gtaagattat ttgaccacag acctttcatt atatattcct cctgttcatt tttattagta
     2881 aatatattaa gtatggtgaa cctaacaagc cagttacaac acctactgga tatctagctg
     2941 gtaaaatatt ttgagagaat atgtctgata acaaaactag taaaattcca accaatccag
     3001 ctaatattgg gcttcttttc ttgccaatat ttaaggctat gggaccagct aaaaaagata
     3061 tacaagctat tggtcctgta attgaagtag aaaaagcagt taaagataca gcgcaaaaaa
     3121 ttaaaacaag ccttgaaagc tcgggatttg ctccaagtcc gattgctatt tcttcaccaa
     3181 gttcaataat ttctagtctt ttattaaaaa ataaaactaa tatagtagca ataatactta
     3241 ctattagaac aagaggtatg tcatctaact ttgtaaaaga taaagagcca ctgagccatc
     3301 tcataacttc ttgtaattca tatcttgcta ctttcaacaa taaaaatgag gtgcctgctc
     3361 ttgtgacagt ttgaaaacca atgcctaata ttatcagtct tgctgctgaa aaaccatctt
     3421 ttttagctag taaaaataat attaaagatg atgttagtcc acaagttatt gaaataattc
     3481 cagtagttaa actatttgtt tttaatacca atatgcaaaa gaccgctgca atagatgaag
     3541 aacttgtgac accgattata tcaggacttg caagaggatt tcttaacata gtttgaaaga
     3601 taaatcctgc caatccaaaa gaccagccag ctataattcc tgctaataat tttggtaatc
     3661 taatttccat aatcgaaaaa ctagctccag gaacagtttc actatttaag actttaatca
     3721 aagttgaaaa agaataactt tcatctccga taagtaaaat gaaaaatgat agactgatta
     3781 ttattaataa aaatagtgag gaaaatagtg ttattctatt ttttcttttt tgaataccta
     3841 taattaaatt ttgcattagt tattaacccc tctatttttc atagttacat aaataagtac
     3901 tggacccccg attattgcag taattatccc tacttcaatt tcacctggtt tacctaacat
     3961 acggccgatt atatcacata taagcaagag ctctgcacct ataaaagatg aagaaatggt
     4021 cattgtgcgt atatctttgc ttataaataa gccacaaaag tgaggaacta taagacctac
     4081 gaagccaata ggtccaccaa ttgcagtaat acttgaacat aaaagcacac ttgcaattat
     4141 tgcaagtgat cttatcctat taacattaac tccaagacca acagccattt catcacccat
     4201 agctaaagcg tttaaatctg atgaaataaa tatagctatc aagtgaccta aaattataaa
     4261 aggtagtagt gtagatatag aagataatgt agctgctcca aggctaccta tttgccaaaa
     4321 tctaaatttg tctaagacgt tattattcgg taaaattaaa aaacttacaa aactgcttaa
     4381 agccatacta acacaagttc ctgataaggc aagttttata ggggtaaggc ctgcttttcc
     4441 gcttacagca atcgcgtata caaaaattgc acttactaag ccaccaatga ttgcaaaact
     4501 tatatggctt atgcttgatg aaattcctaa aaaagaaaga ccaattacta cactaagact
     4561 tgctcctgtg tttataccga gtatacctgg atcagctatt gggtttctag taactgattg
     4621 catcaataca ccgcttatgg caagactaga acctgctaaa attgcaaaaa tagttctagg
     4681 tattctttta tatataattg atttaataaa atcatcattt gtattaccca ttccaaaagc
     4741 tgctaaaaaa tctctgatat taatttcttt tgttccaagc tttaatgaca aaaatattgt
     4801 aataagaaga cctaggcaga ttacaaaaat tatgcctagg tttatttgtt ttttatttcg
     4861 catttttgca tgcatttcct aaaagattta ggtattcttc aatagtatag tttattgaaa
     4921 gtggtgttgg agtgcatgag gctgctaacg gtgtattatc tggaattaca gcaacggcac
     4981 catttttaat tgcatttatt ttacctaaaa gaggatcttt ttgtaaagct tcaagagttt
     5041 tatcatcacc ataagttatg attacatcag catcatttat cttatttgct tcttctgcag
     5101 aaatttcctt tgcaaaacta tcttcactct caaattcttt taatgattca gggaaaacta
     5161 gacctaaatc tgttaaataa tttgctcttg gatctttgct agtataaatc cagaattttg
     5221 atgtatctgc agcattaatc atagtaaata atactttttt tcctttgatt tttcctttga
     5281 tttctggatg tttttctaat tctttggata tacgagcttc agtatttttg attaactcat
     5341 caccttcttt ttccatacct aaggcttttg aatcaatttt aatcatatct ctccataaag
     5401 tttgccaagg tttagatttg tatgctgcta caggagcaat ttttgataga gtgtcataat
     5461 cttctttagt tataccagaa taacctgcta agataacatc tggtttagaa tttgatattg
     5521 cttcaaagtt aagtccatcc aaatcgtcaa ataggttagc tttaccattt agttctttga
     5581 ttttttcttc tgtccatggt aaaactcctt tatcagcact tacaccgtaa tttgcttttg
     5641 aaaatccaac aggaactatt cctaaagcta atgctacatc atgatttccc caagcaatag
     5701 ttgcaactct ttcaggtttt ttatctaata tagtttgacc gaaagcatga tctaaaacta
     5761 ttttatcagg cgcatgctct ttagaagtat tttcttcatt tttaacagaa ttagaagaac
     5821 aagcgctaaa aactatacac atagctaaaa tagctattag aaaaaatttg tttttcataa
     5881 aaactcctta aacatatttc aagtctattg tatcgataat aattatcatt gtcaatagat
     5941 gcagttacaa atttaataat ataatttttt caaaaaagga tctagttttt atttttagtt
     6001 aaattatgtc tatatttttc attaactcat caataaaaat ttgtttgcta atatctcttt
     6061 cttctgattt tgtttcaagg attattgcta catcattcat atttttaggt aaataccaac
     6121 catctggctt atctgaatat cccttgaagc ctaattgatt aaaagtagtt atttgaccag
     6181 taccttgatt gatgttttct tcaacttcat taaagcctat acttctcttg cataatccct
     6241 aacttgatct tctgtcctta aagtcatttt ctattcctcg tcactaaaat tatcttcaaa
     6301 actaataata tcattaggag tgcaagataa agccttacat attctttcta aattcttaaa
     6361 tgtaattggt ttatcctttc ccatttgtgc cataacattt gttgtaagtc ctgccatagc
     6421 tattacatct gttttcttta gtcctttttt tgctaactgt atccataatg gtttatagtt
     6481 aagtgccata atatccctct ttttttcttc attagattta tttaattata gcataaatat
     6541 tgatttcatt caatcttaca ttgatttagt gatttgtttt agagaatttg ttgtgttatt
     6601 ccgtccttat tttgccataa attgttttaa gtgggacctc ttatccttac catttttacc
     6661 tcctaatttt gagtataaaa aagacgatag agtttttaat ttctatcgtc tgagatttac
     6721 atattaaatt ttcatcacaa aataagactc tttaaagaat ctttaaattc attggtatgc
     6781 tgcttacaat atccattatt aaaatggata ctataaacag cacaccaact atttattttt
     6841 tgagttttaa actttggtag aagtcttgaa ctccttatat ttacataact atttgcctct
     6901 ataactatta tgacacgaaa ccaacaagca agttcaagca cctccatatc tttattcaaa
     6961 tgaggactaa gatattcaca aactttatca taaacctctt tatctttttt cataaaaggg
     7021 gcatacaact tagcaaattt atcctaaaat tttttgttgc ctttatcaat catttcaaca
     7081 ctcctttaaa tataaaaatg atcctatcaa tctttatatt gagcctattt tctaattgat
     7141 accttgcaag aaaggaataa tagccgttcc tataccaagt aggaatgtaa taaatgcaga
     7201 aagtcatata ctgtcattct tttctattaa atcattttga agtgtctcaa agcatccatg
     7261 atggcttctt ctttttcagg tgtacactgt ggaataattt gtttatcctt tttagacttg
     7321 ttgtaatgtt ctcgtaattc tattccacat ttctttttta tctgtgcaat atataatgtc
     7381 gaaactttta attcaaattt attccaaaca tattctttga tttgagcata tgttgctttg
     7441 ctctccgcac ttgtcaaatc catctcatcc agctcaattt caacacttat gtgcttatcg
     7501 acatcgagtt tggacaaaag tgctaccgtc tcgacgtgat gcgtttgagg aaatagatcc
     7561 accggctgga ctttcttcaa ttcatatccc aactcttggt atagtttaat atcacgcgcc
     7621 atggttgcga cattgcagga gatataggcg atgcgatcgg ctcctgtttg ggcgcttgct
     7681 ttgataaagc tttctgtcaa gcccttgcgt ggaggatcaa ccaagataac ggttggttga
     7741 ataccttcct tgagccattt cttcatggca ttttcagccg tgtcacagac atagtgggca
     7801 ttagtaatct tgttcaaaga agcattcttc tggctattct ctactgcttc tggaatcagt
     7861 tcaacaccgt agacttcttt gacatgcttg gcgactgata aaccaatggt tccaatacca
     7921 gaataggcat caataatcac atcatctttt tttaactcta caaagtcaat ggctgtttga
     7981 tagagtttct ccgccatttc agtattgact tggtaaaagg ctgggccagc gatttggaag
     8041 tcatttccca acatctggtc cgtaatatag tcttgaccat aaagagtgcg ccactcctta
     8101 ccaaaaatcg cattggtatt ctggtcgttg atattttgca tgacagacac aatctctggg
     8161 aactgcttga taacttgttc aatcaattgg tcaacacgaa aaacttttgg acgagttgtc
     8221 accaaaacga ccatgatttg ccctgaatag tggccacgac gcaccacaag attccgaatt
     8281 aatccagact gttccttttc gtcataaggt tttaaatcaa aacgacggat caggtctcga
     8341 agagctacta cgacttggtc aatgacagga tcctggataa agaaatcttc aaggggcatg
     8401 aggtcgtgcg aattcttacg gaaaaatcct gtttccaaga caccattcac tcgacgaacg
     8461 ggcacctgcg ccttatttcg atacttgact ggatgttcca taccaagcgt ttcagcaact
     8521 tctacatctg caattccagc aatcttgtag agactgtcct tgacttgctt ggttttaaac
     8581 ttgagctgtt ctggataaga aaggtgtcct aaatccgcga ttcctgaacg caggtaagcc
     8641 aaatctagat cttgattacg gtgtggtgac tggacaaggt atttttcaac ttttccaaag
     8701 ccaatctttt tattgacctt gaggacacgc atgagaattt tttcactcgg taaagcattc
     8761 tctacaaaaa agaccaaacc atctaccttg gcaactcctg ccccttcatg ggtcaagtca
     8821 acaatttcaa cttctacaat atcatttttc tttaacattc ttttctcttt ctattggccg
     8881 acaaaaaaga cggcaacgtt acggttacca tccattatac catgaaattt cttaagaacc
     8941 aaaactcttg aagaagttga caagggcttg ccagagggag cttaagaagt taccaccgtc
     9001 ctctagcgcc ttatccgcat caaagttaag gttgatattt ttaaaactgt cgccagcttg
     9061 tgatacgatg ctttgtttaa ggtcatttag ggttttagtg aaatctgcat tgctgaggat
     9121 atcactcttt gagagattca aggcaaaatt gatgatgata ttgatctggt ttcctgttat
     9181 gacctgatca agtttgtaat tttttaaggt atcttcaaca atcttgcgga tatcttcttc
     9241 tgtcagattt cccttgcttt ctttagcttt ggcgagtcct gacttgatat cagctagggc
     9301 aacgtttaat ttattagcat catagcctga tttgtccttg ttttcagcat tgatatctga
     9361 caaagccttt agctcttctt gagccaaatc tttattggct tgcggcacct tggctccatt
     9421 agcttctagc gaatagtaga tcccagccaa agcactctca cctgtaactg gaatgggtgc
     9481 tgctacagtg attttggcgt gttccacacc caaagttacg gctgcatttc ggtacatatc
     9541 ctgagttacc ttagtgatgt tttcaggtgt ttcaatcttg acctcaagtg gcgatttgtc
     9601 acctagcttt tgaatcttgg ctgatgaata caactgtaag ctagagtcat tggccacatt
     9661 catgatttta gaataaacat caggtgtcat ggtcttgagt tctttggtat ctgttgaggc
     9721 attgtagccc agttttttaa gagtttgatt tttttggtct tcagataggg aagaacctag
     9781 gacatattca ggttggacat aggtttcatc gataactttt tgaacatctg ttgctgcatg
     9841 gacgctattc atagctgtta ctgcccacaa gatcgcagcg ctagtcagaa agagtttctt
     9901 tctcataggg aatttcctcc tttacttctt tagagtaata tatctatctt aaagaaaact
     9961 tataacaaaa acacctggtc taaccagatg ttgaaaagag agtgaaacat ttgatgatgt
    10021 aaaggttaag tcgtacctgt ctagaataat aatagtttcc tccatttaca tagagttcag
    10081 caccgtgaaa aatggaaatg gggtgaatat aactataagt ctttccagtc gtattaccaa
    10141 gcaagggggc aacagtctca cgagagtact gtttggctag agccaaggta ttttccttgc
    10201 cattttgggc gataaaatcg atataggcag gtccaaaatt ataggcttga acagctgtcc
    10261 agatatctac acccttcttc tgcgccagat agagattgcc tgtcagagtt tgaatgcctt
    10321 gccgaatgct agagacatta tcattgatgg tgttggtgga accacttgca gactcactag
    10381 actgcataac atcgccttct tttccttttg tttcagtata aatcatagca agcacaagct
    10441 cttcgtttgc tggggtgtct ttttcactca atatttctcg caccatgggt tgataggtca
    10501 tgacttgttt gacatcttga tgaacgcggt aagctttata gccagcaaaa aggaagactg
    10561 ctagtacaag cactcttcga attcgtttaa acattattta ctttggatat cctcgatatt
    10621 tttgattaag atagagtagg ttccattttc gttttggata aactcaacag actcggcgtc
    10681 ttgatagacg ttattgggaa cgatgagctc aattccattt gataaggaga gtttttggtt
    10741 ttcaaatttc tttaattggc gactggcatc aatttcatca aattgaacag gttctggtac
    10801 ggcttctttg acttggtcaa taaagctcaa acgagccgtc agattgttgt caaaaaggtc
    10861 attagccaat ttctcaggtg acaattcatt gctttcttct aggttgttga aaatagctga
    10921 tttgaccttg gattgaaatt gaaaatcatc tgtgttaaaa gattcagcaa ttctctgggc
    10981 tgttttttcc agttccttga tagatttttt aggagaaatc ttaggagcga cagcaagaag
    11041 attatctgaa aaatagttca aaaaagtccc gttgtacttg attcgttttt caatcaggtg
    11101 atacttgcta ctctgaagat tgaccaccaa ggcctcatca gctcctgttc caaatccagg
    11161 caggttattc tgagtcagct tgattggatt atcaacttct cctccgaggt gggtcaaggt
    11221 ctcccgcagg gcaattcgca agaaagcgaa atgttctaca ccttctttag aaaattgaac
    11281 aaaaatcaag tcattggtct tgagattttc agaaatgcta aactcctctt tccagagatt
    11341 agccagcgtt actgatgtct ccaacaaatc gtctgtaata tgattgaaga agggattttc
    11401 ttcttcgaaa atcccagtct tggcttcatc tgaatacaca tgttcaattt ttttacgtag
    11461 gtattcttcg atttttggag taatattgag aaacttatct gctaagaaca gctcggtatc
    11521 atccggactg aactggtgaa taatggcttt cttaatataa atgtccataa aagttttatt
    11581 cctcgtataa tgggaaggca tctgtcaatt ctttgactgc acttctcact tcttctaata
    11641 cagcctcatt ttctgaattc ttaagggttt taatgatgag ttcagccact ttgcgacttt
    11701 cttcttcacc aaatccacgt gcagtaatag ctgctgctcc gatacgaatc ccacttgtct
    11761 tgaatggtga caaggtttcg taagggattg aatttttatt tagggtaata ttgacttcat
    11821 ccagcaagtt ttgagcaact tttccgtttt ctacaacctt agtcacatca acaaggaaga
    11881 gatggttttc agttccacct gaaataatac ggaaatcagg gtcttgcaag aagacatctg
    11941 ccatagcctt gctgttctta attacattgg cagcatattc cttgaaggct ggatccaaaa
    12001 cttctttgaa ggaaactgcc ttagccgcca caacatgctc taaaggaccg ccctgaatac
    12061 ctgggaaaat agctgaattg atttttttag caagttcttc gtcattggtc aaaatcaaac
    12121 caccacgagg tccacgaagg gttttgtggg tcgttgttgt agtgatatga gcgtatggca
    12181 ctgggcttgg gtgaagacca gctgcaacca agccagcgat gtgggccata tcaaccataa
    12241 gcttcgcacc gacagcatct gcgatttcac ggaattttga aaagtcaata atttgagaat
    12301 aggctgaagc accagctaca atcagttttg gttttacttc ttgggcttgt ttcaagatag
    12361 catcaaagtc taagagttcc gtttcaggat caacactata agaaacaaag ttgtaggttt
    12421 gaccagagaa gctaacagga gccccatgag tcaaatgacc acctgatgcc aaatccattc
    12481 ccataaccgt atcacctggc tcaatcaagg acatgtaagc cgcacagtta gcttggcttc
    12541 ctgaatgtgg ttggacattg gcaaatttag caccgaaaat ttcttttgcg cgttcaatag
    12601 caagagtctc tacaacgtct actacatcag ttccaccata ataacggcgt cctgggtaac
    12661 cctcggcata tttatttgtc aagatagacc cttgagctgc cataacagcc ttggaaacta
    12721 cgttttccga agcaattaac tcgatattat tttgttggcg ttcttcttct ttggcaatag
    12781 cattccagag atcagcatca tatgctttaa aatcatcttt gtcaaaaatc ataggtcttc
    12841 tcctttattg tgtgactagt ccattagttt gattttacaa taagaaaatc aaactaaaag
    12901 atgcgaataa accgtttctg cattttatca caagtatagc caactttttc ataaaatgca
    12961 tgagcaccca gacgatgatt ggcagaattt aagcggataa acccataacc acatcttttg
    13021 gcttcttgtt ccaacccttg tagtaaactt ttaccgatac cttgaccttg cgcttgaggt
    13081 gaaactgcta aagctaagat attaaatcct gctttggaat agagtgattc gtaaacttca
    13141 gcgtggacat atccaagtaa gacatgatta gctgcatcct catagccaag taggaaatga
    13201 tgggaatcct gagacagtct agctagttgg ctagccgttt cctctggact aaaagtataa
    13261 cccaaagcct cttggttgat gtcacatatc gctttcacat ctgtttcttg caaatctctt
    13321 agcatttcaa gcctcctcaa aagaaatctc tggcaaccga gcaagaatat cttctcgttt
    13381 aattgcgcct tggcgtaaga ttttcacctt gtctccagac aaatccacaa tagttgaatc
    13441 ctgtccagtt agaaaagcat cgtcttccag acccagaacc tcttggtcaa aatccttcag
    13501 aatttgttca aaggttacac cacttgcctg acctgagata ttggcagacg gcccaatcaa
    13561 gggacctgtc tctcgaatta aatccagtgt gatagggtga ctgggcatcc gaaatccaat
    13621 agttgcaagg tcagaattta cccaataggg aactcggtca ttggcttcga gaataatggt
    13681 caagggacct ggcaaaaagg tctctacaag tttttgtaga taagttggct gattcttaga
    13741 aaagtgcaag atatcctcga aagaggcgat attgagattg agtgccttat ctctaggacg
    13801 acgtttgagt tggtaaacat ggtcaactgc tttttcatct aaggccttgg caaaaagacc
    13861 ataaacagtc tctgtaggta gaacgacagc tccaccattt tccaactctt gtctaatcct
    13921 gtccatcatc aaccacaacc atcctatttt gaccaaattg gtctttgagt gttcgaactt
    13981 ttttttcagg aagatgtttt ctaaaaagtt cgggaacact ttgaccttgc ttgtatccaa
    14041 tttcaaggta aatcttacca ccatccttga gatagtcttt tgcatcttcc gcaattctac
    14101 agtaaatagc taggccatcc tcgtctgcaa agagagctag atgaggctcc gaatgcaaaa
    14161 cattcaagcc tacctctgac tcatcttcac gagagatata gggtggattg gatacaatta
    14221 tatcatattt ttcagaaatt tctgcaaaac aatcagattt tttaaaaaat atattaagat
    14281 tttgatcgct agcattctct gatgcaagct ctaaggcctc ttgagaaaca tctgctgctg
    14341 tcactgacca atctggtcta ttttttgcta gagcgagagc aatagctcca ctacctgttc
    14401 caatatccag aactgagaga ttcgtctcaa gattttcagt tagaataagc tccactaact
    14461 cctctgtttc tggacgagga atcaaaaccc gttcatccac ctttaaatgc attccataaa
    14521 aatctgcctg tccaatgatg tactgagctg gcttgtgagc tgctagttgc tggtaaatat
    14581 cttctacaaa ttgtttttct tcctctgttg tcacctcctg ctggagggca aaaataaagt
    14641 ctgtaaaaga tagatttttc agactacgat agacaaaaga gaggctttcc gcttcctctc
    14701 cttgtcttat caactcttct tcaaaatttg aaaataattg agctaatttc attatttgtt
    14761 taattcttct agtttttgtg tttggtcata aagcaccaag gcatccacaa cttcgtccaa
    14821 tttaccagac aaaatcgtat ctagtttttg gagggtcaag ccgatacggt ggtctgtgac
    14881 acggttttga gggaagttat aagttcggat ccgttctgaa cggtcaccag taccgattgt
    14941 cgacttacgc tcagcgtctt gttcatcctg agcaatctga gcaaagtggt cagcgacgcg
    15001 tgcacggata atcttcatag ccttctcacg gttcttctgc tgggtacgtt cttcctgcat
    15061 ctcaaccttg atattggttg gcaagtgaac gatacgaacg gcagtcgcaa ccttattgac
    15121 gttctgtcca ccagcacctg atgcgtggta aatatcaaca cgaagatctt ttggatcgat
    15181 atcgtattct acttcttcga cttcaggcat gacaagaact gtggcagttg aggtatgaac
    15241 acgaccttgg ctttctgtca cggggacacg ctgcacacgg tgggcacctg attcgtactt
    15301 aagcttagag tatacagact gacctgaaac catagcaacc acttctttaa acccaccgac
    15361 accattcata gaggcttcca tgacttcaaa gcgccagcct tgggcttccg catacttttg
    15421 gtacatagtt agcaaatctc cagcgaaaag tgccgcttcg tctccaccag ctgctccacg
    15481 gatttcaagg atgatattct tgtcatcgtt tggatccttt ggaaggagca aaattttcag
    15541 tttttcttca tattcttctt tttcagcctt ggcatctttg agttcttgct tggccatttc
    15601 ttccaagtcc gcatctccgc ctgattcctt aatcatctct tcggcatcga cgatattttg
    15661 aaggacttgt ttatactcac ggtaggctat tacggtatca cgattggaag cttcttcttt
    15721 tgaaagctcc ataaaacgct tggtgtctga aacgacatca gggtcactca gcaattctcc
    15781 tagttcttca taacggtctt ctacagcttg tagttgatca tagatgttca tttttcttca
    15841 ttctccttat tgatttcagg ggcaaaataa tgtttacggc aaaccgagat ataggtttca
    15901 ttaccaccaa tttggatctg ttctccatcg taaacgggca gtccatcctg tgttcgcaac
    15961 accatggtcg cctttttctt gcaatactga cagatggtct tgatttcgtc aatcttgtct
    16021 gctaaaagca agagatattt ggaaccttcg aacaattcat tgcgaaagtc atttttcaag
    16081 ccaaaagcca tgacgggtat gtctaactcg tccacaacac gagctaggtc ataaacatgg
    16141 tggcgtttga gaaactgggc ttcatcgacc aacacacagt aaggtttttc tggtaggcct
    16201 cggatatagc caaagatatc cgttgtttcc tcaatcgcaa gggcagggcg tttcatgcca
    16261 attcgactcg acacatagcc aacaccgtca cgcgtatcca gagctgaagt cataatcaca
    16321 acaccttttc cttgctcctc atagttatag gccaccttga gaatctcgat tgtctttcca
    16381 gagttcatgg tcccataacg ataatacaac tgtgccatgt ttcttgcttc acgtccattt
    16441 ctaaattttt gctacattct agtatatcat aattttctta agctttaaac ggcaaaatgt
    16501 ggtaaaatgg aagaaatcaa aactagtgga ggaagctatt atgccatttg tacgcatcga
    16561 tttatttgaa ggacgcacgc tcgagcaaaa gaaagctctt gctaaggaag taacggaagc
    16621 agttgtccgc aacactggag cccctcaatc tgctgtccat gtcatcatca acgacatgcc
    16681 agaaggaact tacttcccac aaggggaaat gcgtactaaa taagctagct taagcagaat
    16741 tgcttaggct ttttcaatct ccaagtagca ttcattgaag aaatatccta aatttgttac
    16801 aatttgaaaa gaaacttgga gaatttccaa gaaaatagct attaattaaa ggaaacatta
    16861 tgattacacg tgaatttgat accatcgctg ctatctctac tccactaggt gaaggggcta
    16921 ttggtattgt ccgcctgagc ggaacagaca gttttgctat tgcgcaaaag atttttaaag
    16981 gaaaagactt gaacaaggtt gccagccaca ctctcaacta cggtcacatt attgatcctc
    17041 tgactggtaa agtcatggac gaggtcatgg taggagccat gaaatctcca aaaaccttca
    17101 ctcgtgaaga tattatcgag attaacaccc acggtgggat tgcggtgacc aatgagattc
    17161 tccagctagc tatccgtgaa ggagctcgat tggctgaacc tggtgaattt accaaacgtg
    17221 ccttcctaaa cggtcgcgta gatttgacac aggctgaggc agtgatggac atcatccgtg
    17281 ccaagactga caaggccatg aacattgcag ttaagcaatt agacggctcc ctttctgacc
    17341 tcattaacaa tacccgtcaa gaaatcctca atacacttgc ccaagttgag gtcaatatcg
    17401 actatcctga atatgatgat gttgaggaag ctactactgc tgttgtccgt gagaagacta
    17461 tggagtttga gcaattgcta accaagctcc ttaggacagc ccgtcgcggc aaaatccttc
    17521 gtgaaggaat ttcaacggct atcattggac gtcccaacgt tgggaaatca agccttctca
    17581 acaacctctt gcgtgaggac aaggctatcg taacagatat cgctgggaca acacgagatg
    17641 tcatcgaaga gtacgtcaac atcaatggtg tacctctcaa attgattgat acagccggta
    17701 ttcgtgaaac agatgacata gtggaacaaa tcggtgttga gcgttcgaaa aaagccctca
    17761 aggaagccga cttggttcta ctagtgctaa atgccagtga accactgact gcgcaagaca
    17821 gacaacttct tgaaattagc caagatacca atcgcattat tctacttaat aaaaccgacc
    17881 tgccagaaac gattgaaact tcgaaactac ctgaagacgt tatccgtatt tcagtcctta
    17941 aaaaccaaaa catcgacaag attgaagagc gaatcaacaa cctcttcttt gaaaatgctg
    18001 gcttggtcga gcaagatgct acctacttgt caaacgcccg tcacatttcc ctgattgaaa
    18061 aagcagttga aagcctacaa gccgttaatc aaggtcttga gctggggatg ccagttgatt
    18121 tgcttcaagt tgacttgact cgtacttggg aaatcctcgg agaaatcact ggggatgctg
    18181 ctccagatga acttattacc caactcttta gccaattctg tttaggaaaa taagaaaaat
    18241 ccatgatcct tcattcggtc atggatttta ttgtctttat tagtaatctg gtcttaagac
    18301 ccctgttaca gttgccttag ttgcttcgta gtcgccatct acgacaacct tgataatgcg
    18361 tttggcatct tcttctggtg ctggaacaag aggtagacga gtgggtccag cttcaaatcc
    18421 catatagtta agaactgcct taactggagc aggacttgga taagagaaga gagcattaac
    18481 cttaggaatg aatttacgct gaattgctgc ggctttcttc atatcgcttt ctgcaatggc
    18541 agtaaacatc tcgtgcattt catccccatt tgtatgagag gcaacagaaa taaccccatc
    18601 cgccccaagg ttcatggcat ggaaagcatc tccatcctca cctgtataaa tcaagaactc
    18661 ttcaggcttg tgctcaatca aataagccat attagccaag ctagtacatt ctttgacacc
    18721 gataatattt ggatagtcag ccaagcgaag catggtttct ggagtcaatt cgacaactac
    18781 acgccctgga atgttataga taataattgg taggtcagaa gcatctgcaa tagccttaaa
    18841 gtgctgatac atcccttctt gagaaggttt gttgtagtaa ggaacaatag caagcccagc
    18901 tgcgaaacca ccaaattccg ctacttcttt gacaaactca atagagtcac gcgtatcatt
    18961 agtacctaca cccgcaatca aaggaacgcg tccattgaca accttttgta cagccgcaaa
    19021 caactccaac tcctcatcgt gggtcaaagt tggactctca gcagtcgttc ctgcgagaag
    19081 aattccatcc gtatgatggg ccaataaatg ctcaatcaag gctggaatag catcaaagtt
    19141 aatggaacca tcctcatgga agggggtaat aaaggctgta atgattttac attcttttaa
    19201 atcttgataa gacacgaaaa cacctctcta tttcaaagaa ggagttcatc tgaactccta
    19261 aacgatatga ctattttaat tcaaatttca attcggctgt tggacgaacc aatccacgtt
    19321 catgaagagt ttcagcaatc tgaactgagt tccaagcagc acctttgaga aggttatctg
    19381 aaacaaccca catgtgaatt cctttttctg catccaagtc tttacggata cgaccaacaa
    19441 aggtatcacg cgaaccaact gcattgatgg cttgaggata gatttgatga gctacatcat
    19501 cttcaagaac agcacctggg aaggctgcga tagctgcttt tacttcttcg attggagcca
    19561 cttcttttgt ttcgatataa acagactcag agtgagctga caagactgga atacgcacac
    19621 atgttgcaga tactgcaatg ctatcatctt ccataatttt cttagtttcc ttggtcatct
    19681 tcatctcttc gtacgtgtaa tcattatcag tgaaaacatc aatttgtgga agagcgttaa
    19741 aggcgatagg ataatgtttc ttgtcaccac ctgaaggcaa aatttccgca tgcaaaccac
    19801 atggtttcac accatcattc aagacttcac gaagttcacg ttgtgtctca agaattgctc
    19861 ccataccagc acctgaaacg gcttgataag ttgaaacaat gatacggtcc aagccccatt
    19921 tttggcgaac cggctcaaga gccaccatca tttggattgt tgaacaatta gggcaggcaa
    19981 tgattccgtt gtgagcatca agtgcatgag cattgacctc tggaacaacc aaaggaacat
    20041 ctggattttg acggaaataa gatgtattat ctactactac cacgccagct tttactgcgt
    20101 atggtgcata cttagctgat gtagaaccac ctgctgaaaa gagagcaata tcaactcctt
    20161 caaaagctgt ttcagtcgtt tcttcaatcg taatatcttg atctttaaat ttcaatgact
    20221 tacctgctga acgtgcagaa gcaaggtaac ggattttatc gattggaagt gttgattctt
    20281 ccaacatttt tatcatctga gcaccgacag cacctgtcgc gccgactaca gcaactgtat
    20341 atcccataaa taacctcttt cggaattttc taaaaatttc tataatagaa gtattatact
    20401 actttttcca tgaattgcaa agctttttca tcattttttg gaaaataaaa atccccaatc
    20461 gctagactag ggattaagag gcatcttcat gtgatgagca ggttcacaca actcatcaag
    20521 gtccgctcct gcgttatgac ctccttatgc tcaatagtag cccgaagact acctatcgac
    20581 tcatcgcatc tactattcta ctaaagagaa tgacttttgt caacagacga aactctttat
    20641 actcttcgaa aatctcttca aacttcgtca gcgtcgcctt gccgtatgta tggttactga
    20701 cttcgtcagt ttcatctaca acctcaaaaa catgttttga gctgacttcg tcagttctat
    20761 ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt tactctttga
    20821 ttttcattga gtattagttt tatttacaca ggtgcataag aaatatattg gaaaaattgg
    20881 gggcagacat aacaaaaacc cttgtaaatc aagggctttt ctgtctattt aatgctaatt
    20941 gccgggattg aaccggcgac ctcatcctta ccatggatgc gctctgccaa ctgagctaaa
    21001 tcagcttact taagaagtat actataatca gaaaaacttg tcaagtttcc ttagaaattt
    21061 tccataggaa aaagccaggt aagaactacc tagcttatct tcttctattt acttaaatca
    21121 attcgacgac caattttacc aataataatc gctccaataa tcaatgaagc aaattcaccg
    21181 attcctgttg taaaccaagt aaggaagaat ggtaattctg ctacaatatt taactctgca
    21241 gcgatagtaa acatggaaat tgaaaagagg attgaaaaga agaaatgatc ttttcgaatc
    21301 aatccgttaa agaggtaatc cttgctatat tttgcaaaaa gccaaacacc taaactgagg
    21361 aatactaagg ttgaaccacc accaacaaag acatctagca gtccgaagct aaagaaatta
    21421 gcaatcatac aaccgatggt aactccgatg atgtacttag gattgtaaaa agccataaag
    21481 ttcatcattt ctgaaatacg aaactgataa gcaccatagc tgatggcatt taggggcggt
    21541 gtgacagtca aaacgacgta gatagcagcg acgattgcaa tatctgcaac atcacgaata
    21601 gttaattttt tcatcttttc tcctttggcg gttatccgcg tgtaatatgc ttggtgaaag
    21661 aagctaagca ccaagggttg attcattcaa ccttactagt atagcacaat agcctgcttt
    21721 atgctatact taaagcatga aaaaacctat tcaaaaattt tttaacaatg aaatcttagc
    21781 ctatctcttt tttggccttg cgacaactct agtttcgatt ctctcacgac tagtcattta
    21841 tcaactaagt catcaggaac tccttgctac ggccttggca aatattatcg gtatcttatt
    21901 tgcctttatc acaaatgata cgattgtatt taagcaaaaa aagaaaaata gacttatccg
    21961 tttagtgaaa ttttctcttg ctcgcctttc tacttttctg ttagacttgt ttttaacttt
    22021 tctctttgta acccaatttc ctcacatcat agggcaattc gtaactgaaa acattgataa
    22081 gataaatgct attgaaacaa taattgcaca aatattcatt attatcatca attatatctt
    22141 gagcaaggtc tatattttta gaaaataatg ctccatttat gagcctttta attgccttct
    22201 ataatgattt aggatacaat gaaacacgaa acattgaaag gaaaacagta tgttaaaaaa
    22261 tctaaaatcg ttcttgcttc gaggaaatgt tattgacctt gctgtcggtg ttgtcattgc
    22321 ctctgctttt ggtgctatcg ttacttcact tgtaaacgac attatcactc ctcttatttt
    22381 aaatcccgct ttgaaagctg ctaaagtcga acgtatcgct caactttctt ggcatggagt
    22441 cggctatggt aactttttaa gtgctattat caattttatc tttgtgggta ccgccctctt
    22501 ctttattatc aagggcattg aaaaagcaca gaaactgact ggcataaaga aagaaaaaac
    22561 tgccgaaaaa aaaccaaccg aattggaagt ccttcaagaa ataaaagctc tccttgagaa
    22621 aaaataatcg attaaaagga tctagcgcaa agctaaatcc ttttttcttt actctttggg
    22681 taacttgcct gctttttcaa gcattttttt gataagataa ggcatcttaa cattctcccg
    22741 cccttttttc tcaatcagtt ttttcacaaa ttctggcatt tgtaaatctt cagattcagc
    22801 taaaatgttt ttcgtctcgt ctgaaggaac taactcatca aaggtctctt cttctgggag
    22861 aaattcctta aactcttgat tttcattgac tctaactgta ttgaccaaag catcaatcaa
    22921 acgagaatct gtatttggca ttggtggacg atggtagttt accccaaatt cctggcataa
    22981 gtcataacat tctacatcat tgtcaaacaa gacctcaata tgctcactga tgaaactaat
    23041 aggtacaaaa atataatggt ctggatgttc tgtctgttct ctgagatact ccaaaacatc
    23101 tggtttaatc catggaatac caatatcact ctcactctgc caagtgttgg tatattgttc
    23161 tgaactcaag cccagttttt cagcgactag cttgctattt tcgaaaattt ggtctatata
    23221 aggatcacca aagtccaagg caaaaatggg cacactatgg gctgaaaaga tgactttaaa
    23281 gctgtcttgc tttacttctt cttttaaaat cttagcaatt tcatctgccc aatagtttaa
    23341 gagcgcttct tcctgatacc agtccttaat gaccaaaaat tgaatttgtt tgctttctaa
    23401 aaatttttca tagcccatga cagagtagaa agaataatgg ggctccaaaa tcaagcaaat
    23461 acactgttca attccgtctg cttccatttg accgatcaca tctggaataa agggactgga
    23521 aaacttatta gcaaagtaga cactgtattc attccccagc ctagcttcta ccaaggcaac
    23581 ctcttgacgg gtaatttttt gcagaggcgt gcctccaatt cgtacataat tatcatagag
    23641 agtctgaatc tcgtggtctt ggggtctcac cccacgacga atatttgtga aaaaatcagc
    23701 tacaccttca aaggtaatct cttctggtga accgaaggtc atcattaaaa ttgctttttt
    23761 catgactgct tccttgtgat gtttttatca agtttatttt atcattaatt catcgataag
    23821 taaacgctaa catagggaca ttctcaatct tctgtctttt gtttttctct tctttctatg
    23881 atacaatgga aaaaataaat tcaaaaggag tttttttatg acttatccaa atctcttgga
    23941 ccgcttctta acctacgtta aggtcaacac gcgctctgat gaacactcta ctactactcc
    24001 aagtacacag agtcaggttg acttcgcaac aaatgtccta attcctgaaa tgaaacgtgt
    24061 tggactgcaa aatgtttact atctaccgaa tggttttgct attggaacct tgccagccaa
    24121 cgatccgtct ttaacacgta agattggttt tatatcgcac atggatactg ctgattttaa
    24181 tgctgaagga gtcaatccac aggtaattga aaactacgat ggtggtgtga ttgaactagg
    24241 gaattctggt ttcaaactcg atccagctga cttcaagagt cttgaaaaat atccaggaca
    24301 aacgctcatc acaacagatg gaacaagctt gctaggtgct gatgacaagt caggaattgc
    24361 tgaaattatg acaaccattg aatatctaac tgctcatcct gaaattaagc actgtgagat
    24421 tcgtgttggt tttggtccag atgaagaaat cggtgttggt gccaataaat ttgatgcaga
    24481 agattttgat gtggattttg cctacactgt tgatggtggt ccactaggtg aacttcagta
    24541 cgagactttc tcagccgctg gtgctgaatt gcatttccaa ggccgtaatg tccaccctgg
    24601 tactgccaaa gggcagatgg tcaatgccct tcagctagca attgattttc ataatcaact
    24661 tccagaaaat gaccgacctg agttaactga aggttaccaa ggtttttacc atctaatgga
    24721 tgtgacaggt agtgttgagg aggtgcgtgc aagctacatc attcgtgatt ttgaaaaaga
    24781 tgcctttgaa gcgcgtaaag catccatgca atctatcgct gataagatga atgaagaact
    24841 tgggagcgac cgtgtcactc tcaacttgac agaccagtac tacaatatga aagaagtcat
    24901 tgaaaaagat atgactccaa ttaccattgc taaagccgtt atggaagatc taggtatcac
    24961 gcctattatc gaaccaatcc ggggtggaac agacggctct aagatttcct ttatgggaat
    25021 cccaactccg aatatctttg caggtggcga aaatatgcac ggacgttttg aatacgttag
    25081 ccttcagact atggaacgtg cagttgatac catcattggc atcgtagctt ataaaggcta
    25141 aaaagacgag gtagctcagc tacttcgcct ttctttttat tctactggtt tttcttgatt
    25201 tccagtagtt gtagaagatt ctgttgtttc attttctgaa gttgattcag caggtttaga
    25261 atctcttgta ttgcttggtt tgttttcgtc gctagcagtt tcaatgttag attctgcagt
    25321 tgcgtttggt tggttctcag cactggtgtt atcactattt gcttcagcat ttcttgctgg
    25381 acttgtttct tcacttgcgc tagcttttga ctggatttga tgattcaaaa ctagaatagc
    25441 ttttgtcggt tcaagtaaag ctgttttgtc tttactctta gcagaaagtt gatctaataa
    25501 tgcatccacc ttatcaaagt ccgcatcaga tccattatta ctttctaaat aagagtgaag
    25561 cgacatgaga atatcgtaga gtttttgata gagtacaagt gtctgaggat cttgctcagc
    25621 attttccttt tcttgttgaa gggcgctagc gatacgagtc aaaacatctt ttacctgact
    25681 gtttacttca tccaagtctg catcagcctt gtttgtggca gcttttagat tttctacttc
    25741 ttctgccaag gattgtctga ttccttcttc atggatttgt tccaagagtt gatttgcctt
    25801 gctcaaaaga ctttctactt cttccttgct atctgtcgca gattattggt tgccatctac
    25861 catgtactcc taaaacagga gagttataat ccaagattac aaggccttac agaaataaga
    25921 aatccagata agacaatgtt cgtccaagac gctattcgct tcgcacagca gcacggattc
    25981 aatatgcttt aattttaaag tttaggtgtc aagacctctt tttagtgtgc ccaaaattta
    26041 gagaagtaat caatcaacta acttttattt ttttcaaact ttcagtaaac tgacctaaag
    26101 ctaactcaat ctgtctttgt tcgataggct tgtctttgta gatgcttctg ctatcagcta
    26161 gaagttgatc tacttttgcc aagactgcct tctcataaaa agttccaggt tgatagttgg
    26221 attgcaggga tggaatcttg tttttcaaag ccgcttcata tcccttagtt tgaaccttga
    26281 tgtagtgatt gtggtcgcca cgaggaatca caaaaccttc tgaatcttca cttataattc
    26341 gattggcatc aaaaccatga ccatcttctt cctcatggtg gacatgtagt gacggattac
    26401 ttaatacaga actagaagaa cttcctacct tttccgtgtt agagtgtgat gggggattgt
    26461 taagagatga cttaggaata tagtgatagt gaccccatgt cttactatat aagcatcacc
    26521 tgtatctctg acaatatcat tagggttaaa gacatatgtg gctgctaatt cacctgccga
    26581 caagtcactc tcaggaatga aatgatagtg accaccatgt ggtactatag taggttgaaa
    26641 tagaatatga gcaaattgat aaggggattt taaagtaatt tctaacaatg atttagaaac
    26701 tatgatgtgc tattctaaat tcaactcact atatataacc atcatcggta gtataacgtc
    26761 cctgtaattt tgctacagat acttctgcac tagctccttt atcgtcttta ccatgttctt
    26821 gtttttggcg attgatttca tcttttgttc gtacattttc tgcatgagct tgatctttaa
    26881 ggtaaacata atactttcca tctaccttaa taatatatcc tcccttaacc taactgacaa
    26941 tatcttgatc tttcggctga tagttggggg ctttcattaa tggctcttca ctaaagagcg
    27001 catcaaaagg aactttacca ttatagcagt gataatgatc gccatgagaa gttacataac
    27061 cttgacctgt aatcttaata acaatttgtt ttgcttgaat tccttctttt tgactaacct
    27121 agtctggagt caaattttca gtcttcttag tgtctttatt actgtttaca tatgaaacac
    27181 gatttttatc tgtattggcc tgttagctat gttggttcag agcataaaca cacagactta
    27241 aggaaaggat aacaacagat ccagctgcta tatatttctt tttaaatttc ataattacct
    27301 catttctata attatttata tgatgtcttc attattaaat gattatagaa attaattaac
    27361 caattaatta actagtaaat attccacctc tttttaagtt gtatgtcaag aaattttata
    27421 tattaataat aaaatgaaat tctcccaaag tcagagtttt atttctaact tttgagagaa
    27481 cttcattttt gattcagact ttttctactg ctattcctta cgctatgaga tcagataaat
    27541 tcttttttat cacttctcca cttggcaatc ttaattcaat cgttccatcc atattgaata
    27601 taacactatc taagcctaat ccgtaactag ctgtaaattt ttctaatttt tcttgtacag
    27661 gatctactgc tggagcttcc tctaatgctg aatctaacat agggtcactc cccacattcc
    27721 cttctggatt caacattcca ttatccgttg agttttctgg ttttacaggt ttttcgtttg
    27781 gtgcctctgg taaagaatct gctggtttat tttctgttgg ttggttctca actgttccag
    27841 tagatacttt tccattttca gatggtttat tttcaccatt tccttgaggt gcttctcctg
    27901 taaaatctgc catattcttt ttaatgactt ctcccgatgg taaatataat tcaattgttc
    27961 cgtccatatt aaacaagaca ttttctagct tcatcccata actttcagca aattttgcta
    28021 ctttttcttg tacaggatcc actgtaggaa cttcttctaa cgttgaatta ctagtactat
    28081 tcccagtttc agaaagtttt tctttttcta ccttctcact agtctttggt tcttctacct
    28141 tttcatcaag ttttgagttt tcttgtgctt tattcctttt aaattgtggt agaatacttg
    28201 gtttatcagt ttgattttct ttttccaaga taggtacttc cacaatataa gtcgattgat
    28261 tgtccaaata agcatttgcc atgaaggtta caggaatttt atttccggcc gttctggttg
    28321 ttccttggtt taatttcgga atcggtaatt tgatttcacc aactttatag ttattttcta
    28381 aataagcatt tccatgaaat tcatcaaaca ctctgactaa agcatcagtt cctttaggca
    28441 ctgcaaattg agggttcact cttaaataag tatcccctgc atggaaagga tagaaaatcg
    28501 tttgactggc cattttgtaa gctaaagagg ttggaactgt aaatgtacca tcataactta
    28561 cttctggata atcttttgaa gcgatagtat acttaaatgt ttgtcctggt aaataaggtt
    28621 gatctaattc aaagtttgca atattcccta ctccttctcc aaatacttta ccagatactt
    28681 tctccaatac ttttccatct ggtgttatta attttactag catattgata cctaattttt
    28741 tctccaattc aggcggaaaa ctaaaagaaa cgcgtttttg accattggct agagtaaagt
    28801 tttgattatt aaacgtacta ttttttaaca aattaacaac attcgttaat tcttctccag
    28861 tataaacttt attcccttct tttttagcaa ctccttcttc gggtttaaac agttcatagt
    28921 tactgtgaga atgaccaatt ccaaccggtt tatgttcatc aatcggatct gcatgatggt
    28981 gatctccatg cggataaata atcgcatttt tttctttatt cacgacaata ctttcacgtt
    29041 tgacaccata ttgtttcata atgccagcaa ttttttcttc gattttttta tctaaatctt
    29101 tcatttcttt ggcattactt ggataatcct gttcatgaga tgacaaagaa tctaatccat
    29161 tatgactagt tttaacttcc tctaaatgtt tttgcgcagc cttaatttgc tcttctgtca
    29221 agtccttctt gaagaaataa tgattgtggt ctccgtgact catgacaaaa cctgattcat
    29281 cttcagcgat aatacgatta gcatcaaatc cgtatccatc ttcttcatgt ttctcatgtg
    29341 aagttcctgg attgattgga agagatggag aaggtgttga agaatagctt aactgactcg
    29401 gttgcatatt ttttccagcc agatgtgctt tagctgctgc taattcacta gcagataaat
    29461 cgcttttggg aatgtagtga tagtgacctc catgaggaac gatataagca ttacccgtat
    29521 cttcgataat atcagctgga ttaaagacat aaccatcatt tgtcgtatat cgtccctgag
    29581 accttgctac agcaacatta gagttaacct tctcattatc tttgacatgt tcttgttttt
    29641 gacgattgat ttcatcttta gttcgaacat tatcagcatg agctgcatct ttcaggtaga
    29701 cataatattt tccatcgacc ttgatgatat aaccaccctt gacttcattg acaatatcag
    29761 cgtctttaag ttgatagttt ggatccttca tcaagagttc ttcactaaag agggcatcat
    29821 aaggaacttt cccattatag taatgatagt gatcaccgtg tgacgttaca tagccctgat
    29881 ctgtaatttt gattacaatt tgctcagcct gaattccttc tttctggcta acctggtctg
    29941 gtgtcaagtt ttcacttttc tgacttgact ggctgccatc cacataagag acacgattat
    30001 tgtccttatt ttcctgcgaa cgatgctggt ttagtgcata ggcacataga ctcaaggata
    30061 cgataacagc tgatccagct gctatatatt ttttactaaa tttcataaat ccctcatttc
    30121 aataaatgat gaagtttttt ctcaacttct tttactttat taaatagttt tctaaaccgg
    30181 ttatttaacc atttaattaa ccagtaaata gtttactatt taaaattact tttgtcaagt
    30241 ttctgttacg tttttctaaa aaagagaagt aacacgaaag gttacttctc cataaaatat
    30301 gctccattca ttttactact gtatcggagc cggttgactt ttttttaaca aagccaagag
    30361 actatctact tctgctgaaa tagtgttatt atctttcgtt ccgagaagaa gactactttt
    30421 tagaccagtc aatgtctcca tagcattttg tctaatacta ggatctgtta ctttttctag
    30481 caaggcctcc gcatctgcta tcttagcgtt aataacagaa ttctctactt gaggaatttc
    30541 agcctcatct gtggtatctt cagcttcttc ctctgtctct tccgtatcag tgcttggttt
    30601 ataaagatta tctgctgaag gatttaaacc agcgtgattc tctttttcat cagattcagg
    30661 gtgagttggc tcacttactt catcatgttc cttatcttca tcaggtttac tgtcttggtc
    30721 tgccttattt ttacgaacat ggtc
//
LOCUS       DBEROT010000028        29993 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.28, whole genome shotgun sequence.
ACCESSION   DBEROT010000028 DBEROT010000000
VERSION     DBEROT010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.28"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..343
                     /locus_tag="ACL8CG_001401"
                     /pseudo
     CDS             1..343
                     /locus_tag="ACL8CG_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(418..1338)
                     /gene="cysK"
                     /locus_tag="ACL8CG_001402"
     CDS             complement(418..1338)
                     /gene="cysK"
                     /locus_tag="ACL8CG_001402"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGS1343982.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1623..2258)
                     /locus_tag="ACL8CG_001403"
     CDS             complement(1623..2258)
                     /locus_tag="ACL8CG_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGS1343983.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQIDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2314..3612
                     /locus_tag="ACL8CG_001404"
     CDS             2314..3612
                     /locus_tag="ACL8CG_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1343984.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     SIILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKATKEIQMMNKEAGL"
     gene            3609..4271
                     /locus_tag="ACL8CG_001405"
     CDS             3609..4271
                     /locus_tag="ACL8CG_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGS1343985.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4351..4899
                     /gene="raiA"
                     /locus_tag="ACL8CG_001406"
     CDS             4351..4899
                     /gene="raiA"
                     /locus_tag="ACL8CG_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGS1343986.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5035..7008
                     /locus_tag="ACL8CG_001407"
     CDS             5035..7008
                     /locus_tag="ACL8CG_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGS1343987.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDETSESDISQINSFVANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7005..7457
                     /gene="rplI"
                     /locus_tag="ACL8CG_001408"
     CDS             7005..7457
                     /gene="rplI"
                     /locus_tag="ACL8CG_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGS1343988.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7501..8853
                     /gene="dnaB"
                     /locus_tag="ACL8CG_001409"
     CDS             7501..8853
                     /gene="dnaB"
                     /locus_tag="ACL8CG_001409"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGS1343989.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8855..9121
                     /locus_tag="ACL8CG_001410"
     CDS             8855..9121
                     /locus_tag="ACL8CG_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGS1343990.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9210..10556
                     /gene="cbpD"
                     /locus_tag="ACL8CG_001411"
     CDS             9210..10556
                     /gene="cbpD"
                     /locus_tag="ACL8CG_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGS1343991.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10639..10741
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10812..11102
                     /locus_tag="ACL8CG_001412"
     CDS             10812..11102
                     /locus_tag="ACL8CG_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGS1343992.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11065..11823
                     /locus_tag="ACL8CG_001413"
     CDS             11065..11823
                     /locus_tag="ACL8CG_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1343993.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            11861..12868
                     /locus_tag="ACL8CG_001414"
     CDS             11861..12868
                     /locus_tag="ACL8CG_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1343994.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12868..13596
                     /locus_tag="ACL8CG_001415"
     CDS             12868..13596
                     /locus_tag="ACL8CG_001415"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1343995.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13715..14173
                     /locus_tag="ACL8CG_001416"
     CDS             13715..14173
                     /locus_tag="ACL8CG_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGS1343996.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            14175..16607
                     /locus_tag="ACL8CG_001417"
     CDS             14175..16607
                     /locus_tag="ACL8CG_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGS1343997.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLISKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLTE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(16678..16809)
                     /locus_tag="ACL8CG_001418"
     CDS             complement(16678..16809)
                     /locus_tag="ACL8CG_001418"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1343998.1"
                     /translation="MMKTTDRLEAIGFSFILFENLFKPRQLYLQPQTSVLSNLRLAA"
     gene            17249..17902
                     /gene="rr06"
                     /locus_tag="ACL8CG_001419"
     CDS             17249..17902
                     /gene="rr06"
                     /locus_tag="ACL8CG_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGS1343999.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17899..19239
                     /gene="hk06"
                     /locus_tag="ACL8CG_001420"
     CDS             17899..19239
                     /gene="hk06"
                     /locus_tag="ACL8CG_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGS1344000.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            19322..19849
                     /locus_tag="ACL8CG_001421"
     CDS             19322..19849
                     /locus_tag="ACL8CG_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGS1344001.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19928..22021
                     /gene="cbpA"
                     /locus_tag="ACL8CG_001422"
     CDS             19928..22021
                     /gene="cbpA"
                     /locus_tag="ACL8CG_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HGS1344002.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QVATSSNMAKTEHRKAAEQFDEYINKMIQLDRRKDTQNRTLIIKLSAIKTEYLRELNV
                     LEYKSKAELPSKIKAKLDAAFDQFKKDTLPTEPGKKVAEAKKKVEEAEKKVAEAKKKA
                     KAQKEEDYRNYPTITYKTLELEIAEFDVKVKEAELELVKKEADESRNEGTINQAKAKV
                     ESEKAEATRLKKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKGRRKRGVPG
                     EQATPDKKENDAKSSDSSVGEEALPSPSLKPEKKVAEAEKKVAEAEKKAKAQKEEDHR
                     NYPTNTYKTLELEIAESDVKVKEAELELVKEEAKESRNEEKVNQAKAKVESKKAEATR
                     LEKIKTDRKKAEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPEN
                     PAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMW
                     YFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQYNG
                     SWYYLNANGSMATGWLQYNGSWYYLNANGDMATGWLQNNGSWYYLNANGSMATGWLQY
                     NGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNT
                     TVDSYRVNANGEWVN"
     gene            complement(22251..23231)
                     /gene="dusB"
                     /locus_tag="ACL8CG_001423"
     CDS             complement(22251..23231)
                     /gene="dusB"
                     /locus_tag="ACL8CG_001423"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGS1344003.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(23218..24090)
                     /gene="hslO"
                     /locus_tag="ACL8CG_001424"
     CDS             complement(23218..24090)
                     /gene="hslO"
                     /locus_tag="ACL8CG_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGS1344004.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            24255..25682
                     /locus_tag="ACL8CG_001425"
     CDS             24255..25682
                     /locus_tag="ACL8CG_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1344005.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            25841..27349
                     /gene="glpK"
                     /locus_tag="ACL8CG_001426"
     CDS             25841..27349
                     /gene="glpK"
                     /locus_tag="ACL8CG_001426"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGS1344006.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMIKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            27391..29217
                     /gene="glpO"
                     /locus_tag="ACL8CG_001427"
     CDS             27391..29217
                     /gene="glpO"
                     /locus_tag="ACL8CG_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGS1344007.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            29287..29991
                     /locus_tag="ACL8CG_001428"
     CDS             29287..29991
                     /locus_tag="ACL8CG_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS1344008.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
BASE COUNT         9173 a         5245 c         6903 g         8672 t
ORIGIN      
        1 cgagtcaata ctatttggag cccctttata acctcttgcg agagagacta ttgactcagc
       61 ccttacttca tgcggatgaa acttcttata gggtgctaga gagtgatagt cagctgactt
      121 actattggac ttttttgtct gggaaagctg agaaacaagg gattacgctt taccatcatg
      181 tcctaatcga tttgttcata tcttatttca atccattata aatagtgaga aatatctatc
      241 ctatcttcta gaatgtcttc caaacgtgga aactctcgta aacaaagagg ttttagaggc
      301 ctatttacca tggattaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg
      361 aactatccgt gagttctcta gtctggagat ttttcaatat acttcgttat tggacggtta
      421 caattcataa agtgctgtag agagataacg ttcaccgtta tctggtgcta gggcaaggac
      481 ttttttacct gtacctaatt ttttggcaac ctcgatggct ccgtagatag ctgcagctga
      541 ggaaatccct acaaggaagc cttcttttcc accaatttca cgtccgagtg caagagcgtc
      601 atctgatgtt acacgaacga taccatcata ggctttagta tcaagtgtat caggaataaa
      661 tccagctgag ataccttgaa ttttgtgagg accgggtttt tcaccagata gaatagcaga
      721 ttcatctgct tctactgcaa aaacttgaat gttagaattt tctgatttga gtgcatgaga
      781 aacaccagaa atcgttccac cggtacctac tccagcaaca aaggcatcta atccatcttt
      841 accgaaagca gctagtatct cagctcctgt tgttctttcg tgtacttctg gattagctgg
      901 attgtcaaat tgaagaggaa ggaaaccatc acgttcagca gcgatttctt gagccttagc
      961 aatagcacct ttcattccct cgctaccagg agttaggacg agttcagcac cataagcttg
     1021 gataatttta cgtcgttcta cactcatagt ttcaggcata acgatgacga ctttataccc
     1081 tttagcagca cctacccatg aaagtccaat accagtgttt ccacttgttg cttcaacaat
     1141 agtagaacca ggtttcagaa taccatcttg ttcagctttt tcaatcatgc taagggcaat
     1201 acggtctttt acagatgaac caggattaaa tgcttcaagc tttatataga cgtctgcagc
     1261 accttctggc acgatgttgt taagtttaac aattggtgtt tgaccgatta attcagtaat
     1321 gttgttataa atagacatat gaatacctct ttgtataaga tatctttagt ataacgctat
     1381 ctataccatt tgtaaaatat agaaatccta tcgaagcgat aggatttcta tatatcatag
     1441 atcaaagtca ttaattttca agtgattgcg ttcagctaat tctagtaaat aggtgtgaag
     1501 gaaaacgata tcaggtttcg tttgaattgc ttcattttct agtatatttt ggtacgcatc
     1561 tttttatttt gctcgctaaa gtagttgtga gaatgtcaac gaaacgttgt attattcatt
     1621 gtttacacta agtttacagg aacttcaacc tctcgtaaac cttggtcagt taaagtgact
     1681 tttccattaa aaaactccac aagtgcagct ttaatagttt ctttttcttc tttatcaaca
     1741 taaatcatcg tatcgatttg atctgtaaag tttgtatcca gctccatgag atcatgttct
     1801 ttaaggaagt tactgtactc ttggtactga gcataagaca tttgaatagc aatgccagcc
     1861 tgttctttta tttcaataat accaatttct ttgacagcta aggcgacact gccggcgtaa
     1921 gcacgaatta gtcctccagc gcctagttta ataccaccaa agtagcgtgt cacgaccaca
     1981 cagacattgg tgagattgtg attttctagt accccaagca tgggaacacc agcagtacca
     2041 ctaggttcac catcatcact tgtacgttta atttcactac gttctccaat aataaaggca
     2101 gagcagttat gtgtcgcttt gtagtgttct tttttgatgg cagtaatgaa gtcacgagcc
     2161 tcttcttcgc tataaacacg cttggcatgg cagataaagc gagatttttt gatttcttct
     2221 tggacttgac cgtcctcttt aattgttcta aattccatga tttaattgta ctaaaaaatc
     2281 atctaaagtg ctagttttta cgaataaaga agtatgaaag taaatttaga ttatctcggt
     2341 cgtttattta ctgagaatga attaacagaa gaagaacgtc agttggcgga gaaacttcca
     2401 gcaatgagaa aggagaaggg gaaacttttc tgtcaacgct gtaatagtat tattctagaa
     2461 gaatggtatt tgcccatcgg tgcttactat tgtcgagagt gcttgctgat gaagcgagtc
     2521 agaagtgatc aaactttata ctattttccg caggaggatt ttccgaagca agatgttctc
     2581 aaatggcgcg gccaattaac tccttttcaa gagaaggtgt cagagggact gcttcaagca
     2641 gtagacaagc aaaagccaac cttagttcat gcggtaacag gagctggaaa gacagaaatg
     2701 atttatcaag tagtggctaa agtgatcaat gcgggtggtg cagtgtgttt ggctagtcct
     2761 cgcatagatg tttgtttgga gctgtacaag cgcctgcaac aggatttttc ttgcggaata
     2821 gctttgctac atggagaatc ggaaccttat tttcgaacac cactagttgt tgcaacaacc
     2881 catcagttat tgaagtttta tcaagctttt gatttgctga tagtggatga agtagatgct
     2941 tttccttatg ttgataatcc catgctttac cacgctgtca agaatagtgt aaaggagaat
     3001 ggattgagaa tctttttaac agcgacttcg accaatgagt tagataaaaa ggtccgttta
     3061 ggagaactaa aaagactgaa tttaccgaga cggtttcatg gaaatccgtt gattattcca
     3121 aaaccaattt ggttatcgga ttttaatcgc tacttagaca agaatcgttt gtcaccaaag
     3181 ttaaagtcct atattgagaa gcagagaaag acagcttatc cgttactcat ttttgcttca
     3241 gaaattaaga aaggggagca gttagcagaa atcttacagg agcaatttcc aaatgagaaa
     3301 attggctttg tatcttctgt aacagaggat cgattagagc aagtacaagc ttttcgagat
     3361 ggagaactga caatacttat cagtacgaca atcttggagc gtggagttac cttcccttgt
     3421 gtggatgttt tcgtagtaga ggccaatcat cgtttgttta ccaagtctag tttgattcag
     3481 attggtggac gagttggacg aagcatggat agaccgacag gagatttgct tttcttccat
     3541 gatgggttaa atgcttcaat caagaaggcg actaaggaaa ttcagatgat gaataaggag
     3601 gctggtctat gaagtgcttg ttatgtgggc agactatgaa gactgtttta acttttagta
     3661 gtctcttact tctgaggaat gatgactctt gtctttgttc agactgtgat tctacttttg
     3721 aaagaattgg ggaagagaac tgtccaaatt gtatgaaaac agagttgtca acaaagtgtc
     3781 aagattgtca actttggtgt aaagagggag ttgaagtcag tcatagagcg atttttactt
     3841 acaatcaagc tatgaaggat tttttcagtc ggtataagtt tgatggagac ttcctgttaa
     3901 gaaaagtttt cgcttcattt ttaagtgagg agttgaaaaa gtacaaagag tatcaatttg
     3961 ttgtaattcc cctaagtcct gatagatatg ctaatagagg atttaatcag gttgagggct
     4021 tggtagaggc agcaggcttt gagtatctgg atttattaga gaaaagagaa gagagagcca
     4081 gttcttctaa aaatcgttca gagcgcttgg ggacagaact tcctttcttt attaaaagtg
     4141 gagtcactat tcctaaaaaa atcctactta tagatgatat ctatactaca ggagcaacta
     4201 taaatcgtgt taagaaactg ttggaagaag ctggtgctaa ggatgtaaaa acattttccc
     4261 ttgtaagatg aggaaaaaat ttgcaaaaat agaatgaaag cgttataata aaatcataaa
     4321 aacaaaaatg tttagaaaga aggtactcat atgattaaat atagtatccg tggtgaaaac
     4381 ctagaagtaa cagaagcaat tcgtgattat gtagtttcta aactcgaaaa gatcgaaaag
     4441 tacttccaac cagaacaaga gttggatgcc cgaattaact taaaagttta tcgtgaaaaa
     4501 acggctaaag tggaagtaac gattccgctt ggatctatta ctctccgcgc agaagatgta
     4561 tctcaagata tgtatggttc aattgacctt gtaactgata aaattgaacg tcagattcgt
     4621 aaaaataaaa caaaaatcga gcgtaaaaat aaaaataagg tagcaactgg tcaattattt
     4681 acagatgctt tggtggaaga ttcaaatgtt gtccagtcta aagttgttcg ttcaaaacaa
     4741 attgatttaa aaccaatgga tttggaagaa gcaattctac aaatggattt attggggcat
     4801 gatttcttta tctatgtgga tgttgaagat cagacaacca atgtgattta tcgtcgtgag
     4861 gatggcgaaa ttggtttgtt agaggttaaa gaatcttaat ttcaatatgt gtaaaggtag
     4921 gtttactgaa ttgtaaacta cctttttctt ataattgata gaattactga ttacactttt
     4981 aaaaagtcgc tttttgaggg gtattatggt ataatgggtg ccaagaggtt ttgaatgaaa
     5041 aaattttatg taagtccaat ttttcctatt ctagtaggat tgattgcgtt tggagtctta
     5101 tccactttca ttatttttgt taataataat ctgttgacgg ttttaatttt gtttcttttt
     5161 gtaggaggct atgttttttt atttaagaaa ctgagagtgc attatacaag gagtgatgta
     5221 gaacagatac agtatgtaaa ccaccaagcg gaagaaagtt tgacagctct attggaacag
     5281 atgcctgtag gtgttatgaa attgaattta tcttctggag aggttgagtg gtttaatccc
     5341 tatgctgaat tgattttgac caaggaagat ggtgattttg atttagaagc tgttcaaacg
     5401 attatcaagg cttcagtagg aaatccgtct acttatgcca agcttggtga gaagcgttat
     5461 gctgttcata tggatgcttc ttccggtgtt ttgtattttg tagatgtatc cagggaacaa
     5521 gccataacag atgaattggt aacaagtaga ccagtgattg ggattgtctc tgtggataat
     5581 tatgatgatt tggaggatga aacttctgag tcagatatta gtcaaatcaa tagttttgta
     5641 gctaatttta tatcagagtt ttcagaaaaa cacatgatgt tttctcgtcg ggtaagtatg
     5701 gatcgatttt atctatttac tgactacacg gtgcttgagg gcttgatgaa tgataaattt
     5761 tctgttattg atgctttcag agaagagtcg aaacagagac agttgccctt gaccttaagt
     5821 atgggatttt cttatggcga tggaaatcat gatgagatag ggaaagttgc tttgctcaat
     5881 ttgaacttgg ctgaagtacg tggtggcgac caggtggttg ttaaggaaaa cgacgaaacg
     5941 aaaaatccag tttattttgg tggtgggtct gctgcttcaa tcaagcgtac acggactcgt
     6001 acgcgcgcta tgatgacagc tatttcagat aagattcgga gtgtagatca ggtttttgta
     6061 gtcggtcaca aaaatttaga catggatgct ttgggctctg ctgtaggtat gcagttgttc
     6121 gccagcaatg tgattgaaaa tagctatgct ctttatgatg aagaacaaat gtctccagat
     6181 attgaacgag ctgtttcatt catagaaaaa gaaggagtta cgaagttgtt gtctgttaag
     6241 gatgcaatgg ggatggtgac caatcgttct ttgttgattc ttgtagacca ttcaaagaca
     6301 gccttaacat tatcaaaaga attttatgat ttatttaccc aaaccattgt tattgaccac
     6361 catagaaggg atcaggattt tccagataat gcggttatta cttatatcga aagtggtgca
     6421 agtagtgcca gtgagttggt aacggaattg attcagttcc agaattctaa gaaaaatcgt
     6481 ttgagtcgta tgcaagcaag tgttttgatg gctggtatga tgttggatac taaaaatttc
     6541 acctcgcgag taactagtcg gacatttgat gttgctagct atctcagaac gcgcggaagt
     6601 gatagtattg ctatccagga aatcgctgcg acagattttg aagaatatcg tgaggtcaat
     6661 gaacttattt tacaggggcg taaattaggt tcagatgtac taatagcaga ggctaaggac
     6721 acgaaatgct atgatacagt tgttattagt aaggcagcag atgccatgtt agccatgtca
     6781 ggtattgaag cgagttttgt tcttgcgaag aatacacaag gatttatctc tatctcagct
     6841 cgaagtcgta gtaaactgaa tgtacaacgg attatggaag agttaggcgg tggaggccac
     6901 tttaatttgg cagcagctca aattaaagat gtaaccttgt cagaagcagg tgaaaaactg
     6961 acagaaattg tattaaatga aataaaggaa aaggagaaag aagaatgaaa gtaatctttt
     7021 tagcagatgt taaaggaaaa ggtaaaaaag gcgaaattaa ggaagtacca acagggtatg
     7081 cgcaaaactt tcttatcaaa aagaatctag ccaaagaagc gactgctcaa gctgtaggtg
     7141 aacttcgagg taaacaaaaa tcggaagaaa aagctcacgc tgagatgatt gcagaaggaa
     7201 aagcaattaa agcacaactt gaagcagaag aaactgttgt agaatttgtt gaaaaagttg
     7261 gtccagatgg tcgtaccttt ggttctatta ccaataagaa gattgcagaa gaattgcaaa
     7321 agcaatttgg aattaagatt gataaacgtc atattcaagt acaagctccg attcgagcgg
     7381 ttggtttgat tgatgtgcca gtgaaaatct atcaagatat cacaagtgta atcaatcttc
     7441 gtgtgaaaga aggataagtt tacactttct tgacaagatt gtaaaaggaa gggaagtctg
     7501 atggcagaag tagaagagtt acgagtacaa cctcaagata tcttagctga gcaatccgtt
     7561 ttaggggcta tctttattga tgagagtaaa cttgtttttg tgcgagaata cattgagtct
     7621 cgggactttt ttaagtatgc ccatcgtttg attttccaag ccatggtcga tttatccgat
     7681 cgtggtgatg ccatagatgc aacaacggtt cgtactatcc ttgataatca aggtgattta
     7741 cagaatattg gtggcttgtc ttacttggtt gagattgtta attctgtgcc aacttctgct
     7801 aatgcggagt attatgctaa gattgttgca gaaaaagcaa tgctacgtcg tttaattgcc
     7861 aagttgacag agtctgtcaa ccaagcttac gaagcgtcac aaccagctga tgaaattatt
     7921 gctcaggcag aaaaagggct gattgatgtc agtgaaaatg caaatcgaag cgggtttaag
     7981 aacattcgag atgtgttgaa tctcaacttt ggaaatctgg aagctcgctc gcaacaaacg
     8041 accgatatta caggtattgc gacaggttat cgtgatttgg atcatatgac aacaggactt
     8101 catgaggagg agttgattat cttagcagct cgtccagcag ttggtaagac agcatttgcc
     8161 ttgaatatcg ctcagaacat tgggactaag ttggacaaaa cggttgctat tttttcactc
     8221 gaaatgggtg cggaaagctt ggtagatcgt atgttagctg cagaaggctt agtggagtca
     8281 cattctatcc gtacagggca attgacagat gaggagtggc aaaaatatac tattgctcag
     8341 ggtaatctag ctaacgccag tatctatatc gatgatacgc caggtattcg gattacagag
     8401 attcgttctc gttctcgtaa attggctcaa gaaactggaa atcttggttt gattttgata
     8461 gactatttgc aacttatcac gggaactggt cgagaaaatc gtcaacaaga agtttctgaa
     8521 atttctcgtc agttgaaaat actagccaag gaattgaagg ttccagtaat cgctctgagt
     8581 cagctttctc gtggtgtaga acaacgtcag gacaagagac cggtcttgtc tgatattcgt
     8641 gaatctgggt ctattgagca ggacgctgat atcgtagctt ttctctatcg cgatgactac
     8701 tatgaacgtg gtggtgaaga agaggagggt atcccaaata ataaggtgga agttattatc
     8761 gagaaaaacc gtagtggagc tcgtggaaca gtggaattga ttttccaaaa agaatacaat
     8821 aaattttcaa gtatctcaaa gagggaggca taagatgtca gatgcattta cagatgtagc
     8881 caagatgaaa aaaatcaaag aagaaatcaa ggcacatgag ggacaagtcg tagaaatgac
     8941 tttggagaat ggtcgtaagc gccaaaaaaa tagattgggt aagctaattg aagtttatcc
     9001 atctctattt attgtggagt ttggggatgt ggaaggagat aaacaagtta atgtttacgt
     9061 tgaatccttt acttactcag atattcttac agaaaagaat ttgattcatt atcttgacta
     9121 aagtgagaaa ttttctcact ttttcttttt tctccgaata atttaggtga aggcaatcat
     9181 cgctttatat tatttttcaa ggaggaagaa tgaaaatttt accgtttata gcaagaggaa
     9241 caagttatta cttgaagatg tcagttaaaa agcttgttcc ttttttagta gtaggattga
     9301 tgctagcagc tggtgatagt gtctatgcct attccagagg aaatggatcg attgcgcgtg
     9361 gggatgatta tcctgcttat tataaaaatg ggagccagga gattgatcag tggcgcatgt
     9421 attctcgtca gtgtacttct tttgtagcct ttcgtttgag taatgtcaat ggttttgaaa
     9481 ttccggcagc ttatggaaat gcgaatgaat ggggacatcg tgctcgtcgg gaaggttatc
     9541 gtgtagataa tacaccgacg attggttcca ttacttggtc tactgcagga acttatggtc
     9601 atgttgcctg ggtgtcaaat gtaatgggag atcagattga gattgaggaa tataactatg
     9661 gttatacaga atcctataat aaacgagtta taaaagcaaa cacgatgaca ggatttattc
     9721 attttaaaga tttggatggc ggcagtgttg ggaatagtca atcctcagct tcaacaggcg
     9781 gaactcatta ttttaagacc aagtctgcta ttaaaactga acccctagct agcggaactg
     9841 tgattgatta ctattatcct ggggagaagg ttcattatga tcagatactt gaaaaagacg
     9901 gctataagtg gttgagttat actgcctata atggaagcta tcgttatgtt caattggagg
     9961 ctgtgaataa aaatcctcta ggtaattctg ttctttcttc aacaggtgga actcattatt
    10021 ttaagaccaa gtctgctatc aaaactgaac ccctagttag cggaactgtg attgattact
    10081 attatcctgg ggagaaggtt cattatgatc agatacttga aaaagacggc tacaagtggt
    10141 tgagttatac tgcctataat ggaagtcgtc gctatataca gctagaggga gtgacttctt
    10201 cacaaaatta tcagaatcaa tcaggaaata tctctagcta tggatccaat aatagttcaa
    10261 ctgtcggttg gaagaaaata aatggtagtt ggtatcattt caaatcaaat ggttctaaat
    10321 caacaggatg gctgaaagac ggttctagct ggtattattt gaaattatct ggtgaaatgc
    10381 agacaggatg gttaaaggaa aatggctcgt ggtattatct gggtagttca ggggcaatga
    10441 aaacaggctg gtaccaggtc tctggtaagt ggtattattc ttactcttca ggcgccttag
    10501 ctgttaatac gacggtggat ggctacagag taaacagtga tggagaacga gtatagaaaa
    10561 ttggagtagg agaaatttcc tgctcttttc tgtaagcagt ttccttgaca tttttcttat
    10621 tttgcgctat catatataca tataatatat gggagtctgt gtacagtctg agaggaagtg
    10681 ttaaacttcg accgcacctg atctgggtaa tgccagcgga gggaacgata cttagtctaa
    10741 ttttgcacct tttccatgta tggtaaaggt ttttcttttt ttaaaaagga aaacgagaag
    10801 aggaggttct tatgaaagca agcattgcct tgcaagtttt acccctagta caggggattg
    10861 atcggatagc tgttattgat caggtcattg cttatctgca aactcaagaa gtgacgatgg
    10921 tagtgacacc atttgaaacg gtcttggaag gggagtttga tgagcttatg cgcattctaa
    10981 aagaagcgct ggaagtggca gggcaggagg cagacaatgt ctttgccaat gtcaaaataa
    11041 atgtaggaga gattttaagt attgatgaga aacttgagaa gtatactgag acgacacatt
    11101 agtctattgg gctttctcgg agtattgtca atctggcagt tagcaggttt tcttaaactt
    11161 ctccccaagt ttatcctgcc gacacctctt gaaattctcc agccctttgt tcgtgacaga
    11221 gaatttctct ggcaccatag ctgggcgacc ttgagagtgg ctttactggg gctgattttg
    11281 ggagttttga ttgcctgtct tatggctgta ctcatggata gtttgacttg gctcaatgac
    11341 ctgatttacc ctatgatggt ggtcattcag accattccga ccattgccat agctcctatc
    11401 ctggtcttgt ggctaggtta tgggattttg cccaagattg tcttgattat cttaacgaca
    11461 acctttccca tcatcgtcag cattttggac ggttttaggc attgcgacaa ggatatgctg
    11521 actttgttta gtctgatgcg ggccaagcct tggcaaatcc tgtggcattt taaaatcccg
    11581 gttagcctgc cttactttta tgcaggtctg agggtcagtg tctcctacgc ctttatcaca
    11641 actgtggtat ctgagtggtt gggaggtttt gaaggtcttg gtgtttatat gattcagtct
    11701 aaaaaactgt ttcagtatga taccatgttt gccattatta ttctggtgtc gattatcagt
    11761 cttttgggta tgaagctggt cgatattagt gaaaaatatg ttattaaatg gaaacgtact
    11821 taaaatagag cgtttttgaa aaagaaaaga ggaaatcaaa atgaagaaaa catggaaagt
    11881 gtttttaacg cttgtaacag ctcttgtagc tgttgtgctt gtggcctgtg gtcaaggaac
    11941 tgcttctaaa gacaacaaag aggcagaact taagaaggtt gactttatcc tagactggac
    12001 accaaatacc aaccacacag ggctttatgt tgccaaggaa aaaggttatt tcaaagaagc
    12061 tggagtggat gttgatttga aattgccacc agaagaaagt tcttctgact tggttatcaa
    12121 cggaaaggca ccatttgcag tgtatttcca agactacatg gctaagaaat tggaaaaagg
    12181 agcaggaatc actgccgttg cagctattgt tgaacacaat acatcaggaa tcatctctcg
    12241 taaatctgat aatgtaagca gtccaaaaga cttggttggt aagaaatatg ggacatggaa
    12301 tgacccaact gaacttgcta tgttgaaaac cttggtagaa tctcaaggtg gagactttga
    12361 gaaggttgaa aaagtaccaa ataacgactc aaactcaatc acaccgattg ccaatggcgt
    12421 ctttgatact gcttggattt actacggttg ggatggtatc cttgctaaat ctcaaggtgt
    12481 agatgctaac ttcatgtact tgaaagacta tgtcaaggag tttgactact attcaccagt
    12541 tatcatcgca aacaacgact atctgaaaga taacaaagaa gaagctcgca aagtcatcca
    12601 agccatcaaa aaaggctacc aatatgccat ggaacatcca gaagaagctg cagatattct
    12661 catcaagaat gcacctgaac tcaaggaaaa acgtgacttt gtcatcgaat ctcaaaaata
    12721 cttgtcaaaa gaatacgcaa gcgacaagga aaaatggggt caatttgacg cagctcgctg
    12781 gaatgctttc tacaaatggg ataaagaaaa tggtatcctt aaagaagact tgacagacaa
    12841 aggcttcacc aacgaatttg tgaaataatg acagaaatta gactagagca cgtcagttat
    12901 gcctatggtc aggagaggat tttagaggat atcaacctac aggtgacttc aggcgaagtg
    12961 gtttccatcc taggcccaag tggtgttgga aagaccaccc tctttaatct aatcgctggg
    13021 attttagaag ttcagtcagg gagaattgtc cttgatggtg aagaaaatcc caaggggcgc
    13081 gtgagttata tgttgcaaaa ggatctgctc ttggagcaca agacggtgct tggaaatatc
    13141 attctgcccc tcttgattca aaaggtggat aaggcagaag ctatttcccg agcggataaa
    13201 attcttgcga ccttccagct gacagctgta agagacaagt atcctcatga acttagcggt
    13261 gggatgcgcc agcgtgtagc cttactccgg acctaccttt ttgggcacaa gctctttctc
    13321 ttagatgagg cctttagcgc cttggatgag atgacaaaga tggaactcca cgcttggtat
    13381 cttgagattc acaagcagtt gcagctaaca accctgatca tcacgcatag tattgaggag
    13441 gccctcaatc tcagcgaccg catctatatc ttgaaaaatc gccctgggca gattgtttca
    13501 gaaattaaac tagattggtc tgaagatgag gacaaggaag tccaaaagat tgcctacaaa
    13561 cgtcaaatct tggcagaatt aggcttagat aagtagaaaa atagggagtt ggtgaagatt
    13621 atcctttacc agcgcccttt ttcttttaaa aatgagaaaa tttcggtata atagtcaaac
    13681 aaggtcaagg tttaaagaga gaggtgggtt tgttatgaga tttaaaaata catcggatca
    13741 tattgaggcc tacatcaagg cgattttaga tcaatctggt atcgtggagt tgcaacggag
    13801 tcagttggca gatacctttc aggttgttcc tagtcagatt aactacgtga tcaagacacg
    13861 ctttacggaa agtagaggct acttggttga aagtaagcgt ggtggtggag gctacattcg
    13921 tataggacga attgagtttt ctagtcatca tgaaatgctc cgggagctgc tttactcgat
    13981 tggtgagcga gtcagtcaag aaatttatga ggatattctc cagcttttgg ttgagcagga
    14041 attgatgacc aagcaggaga tgaatttgct agaatcagta gctttggatc gcgttttagg
    14101 agaagaagct ccagttgttc gagcaaacat gctacgtcag atcatacaag aggtagatag
    14161 aaaagggaag taagatgaac tattcaaaag cattgaatga atgtatcgaa agtgcctaca
    14221 tggttgctgg acattttgga gctcgttatc tagagtcttg gcacttgttg attgccatgt
    14281 ctaatcacag ttatagtgta gcaggggcaa ctttaaatga ttatccgtat gagatggacc
    14341 gtttagaaga ggtggctttg gaactgactg aaacggacta tagccaggat gaaaccttta
    14401 cggaattgcc gttctcccgt cgtttgcagg ttctttttga cgaagcagag tatgtagcgt
    14461 cagtggtcca tgctaaggtg ctagggacag agcacgtcct ctatgcgatt ttgcatgatg
    14521 gcaatgcctt ggcgactcgt atcttggaga gggctggttt ttcttatgaa gacaagaaag
    14581 atcaggtcaa gattgctgct cttcgtcgaa atttagaaga acgggcaggc tggactcgtg
    14641 aagatctcaa ggctttacgc caacgccatc gtacagtagc tgacaagcaa aattctatgg
    14701 ccaatatgat gggcatgccg cagactccga gtggtggtct cgaggattat acgcatgatt
    14761 tgacagagca agcgcgttct ggcaagttag aaccagtcat cggtcgggac aaggaaatct
    14821 cacgtatgat tcaaatcttg agccgtaaga ctaagaacaa ccctgtcttg gttggggatg
    14881 ctggtgtcgg gaaaacagct ctggcccttg gtcttgccca gcgtattgct agtggtgacg
    14941 tgcctgcgga aatggctaag atgcgcgtgt tagaacttga tttgatgaat gtcgttgcag
    15001 ggacacgctt ccgtggtgac tttgaagaac gcatgaataa tatcatcaag gatattgaag
    15061 aagatggcca agtcatcctc tttatcgatg aactccacac catcatgggt tctggtagcg
    15121 ggattgattc gactctggat gcggccaata tcttgaaacc agccttggcg cgtggaactt
    15181 tgagaacggt tggtgccacc actcaggaag aatatcaaaa acatatcgaa aaagatgcgg
    15241 ctctttctcg tcgtttcgct aaagtgacga ttgaagaacc aagtgtggca gatagtatga
    15301 ctattttaca aggtttgaag gcgacttatg agaaacatca ccgtgtacaa atcacagatg
    15361 aagcggttga aacagcggtt aagatggctc atcgttattt aaccagtcgt cacttgccag
    15421 actctgctat cgacctcttg gacgaagcag cagcaacagt gcaaaataag gcaaagcatg
    15481 taaaagcaga cgattcagat ttgagtccag ctgacaaggc cctgatggat ggcaagtgga
    15541 aacaggcagc ccagctaatc tcaaaagaag aggaagtacc tgtctacaaa gacttggtga
    15601 cagagtctga tattttgacc accttgagtc gcttgtcagg aatcccagtt caaaagctga
    15661 ctcagactga cgctaagaaa tatctaaatc ttgaagcaga actccataaa cgggttatcg
    15721 gtcaagatca agctgtttca agtattagtc gtgcgattcg ccgtaatcag tcaggaattc
    15781 gcagtcacaa gcgtccgatc ggttccttta tgttcctagg acccacaggt gtcggtaaga
    15841 ccgagttggc caaggctttg gcagaagttc tctttgatga cgaatcagcc cttatccgct
    15901 ttgatatgag tgagtatatg gagaaattcg cagccagccg tctaaatgga gctcctccag
    15961 gctatgtggg ttacgaagaa ggtggggagt tgacagagaa ggttcgcaat aaaccctatt
    16021 ccgttctcct ctttgatgag gtagagaagg ctcacccaga tatctttaat gttctcttgc
    16081 aggttctgga tgacggtgtc ttgacagata gcaagggacg caaggtcgat ttttcaaata
    16141 ccattatcat tatgacatcg aacctaggtg cgactgccct tcgtgatgat aagactgttg
    16201 gttttggggc taaggatatt cgttttgacc aggaaaatat ggaaaaacgc atgtttgaag
    16261 aactgaaaaa agcttataga ccggaattca tcaaccgtat tgatgagaag gtggtcttcc
    16321 atagcctatc tagtgatcat atgcaggaag tggtgaagat tatggtcaag cctttagtgg
    16381 caagtttgac tgaaaaaggc attgacttga aattacaagc ttcagctctg aaattgttag
    16441 caaatcaagg atatgaccca gagatgggag ctcgcccact tcgtagaacc ctgcaaacag
    16501 aagtggagga caagttggca gaacttcttc tcaagggaga tttagtggca ggcagcacac
    16561 ttaagattgg tgtcaaagca ggccagttaa aatttgatat tgcataaaag aataaaagta
    16621 tcagcatctg accataagtc acagtggagt gaaattcaat gaaaatcaaa gagcaaacta
    16681 ggcagctagc cgcaggttgc tcaaaacact ggtttgaggt tgcagataga gctgacgtgg
    16741 tttgaagaga ttttcgaaga gtatgaaact aaaacctata gcttctaaac gatccgtggt
    16801 tttcatcatt caacacaaaa ttcatatgtt tattaccctc cgtcgtattt gtcttagagc
    16861 gtgtgtagta gaaaaagagc agtcttatct gaaattttta ttctttcaaa agagacctgt
    16921 ttcttttttg catgtcaaat ccgttctagc tggtatttga aaaatcaaac taatattcaa
    16981 tgaaaatcaa agaacaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg
    17041 ttgtagatag agctgacgtg gtttgaagag attttcgaag agtataagct gcaagatgaa
    17101 tgattttctt gtattgacgt tgttgttgac aaaaagtagc ggataaatga aatccattcc
    17161 attatcatag atgataggct ggtaggaaat tttcaaatag catacaggaa atagatgtat
    17221 ggagttctgg tagtagaaag ggagagagat gaacatttta gttgcagatg acgaggaaat
    17281 gattagagaa ggaattgcag catttctgac agaagagggt tatcatgtca ttatggctaa
    17341 ggatggacaa gaggtcttgg aaaaatttca agatctccct atccatctca tggtactgga
    17401 tttaatgatg cctaggaaga gtggttttga agtgttaaaa gaaatcaatc aaaagcacga
    17461 tattcctgtc atcgtcttga gtgctctggg agatgaaact actcagtcac aggtatttga
    17521 tctctatgct gatgatcatg tgacaaaacc tttttctttg gtactgcttg tcaagcgtat
    17581 taaggcgctt atcagacgtt actacgtcat agaggatatt tggcgatatc aggatgtaac
    17641 agtggatttt acctcttaca aagcacatta taaaaatgaa gaaattgatc tcaaaccaaa
    17701 ggaattactg gtactaaagt gtttgattca gcataaaaat caagttttaa gtagagagca
    17761 gatattggaa gaaatttcaa aagatgtagc tgatttacct tgtgataggg tcgttgatgt
    17821 ctatattcgt actcttcgca aaaaattagc tttagattgt atcgtgactg tgaaaaatgt
    17881 tgggtataag attagcttat gataaaaaat cctaaattat taaccaagtc ttttttaaga
    17941 agttttgcaa ttctaggtgg tgttggtcta gtcattcata tagctattta tttgaccttt
    18001 cctttttatt atattcaact ggagggggaa aagtttaatg agagcgcaag agtgtttacg
    18061 gagtatttaa agactaagac atctgatgaa attccaagct tactccagtc ttattcaaag
    18121 tccttgacca tatctgctca ccttaaaaga gatattgtag ataagcggct ccctcttgtg
    18181 catgacttgg atattaaaga tggaaagcta tcaaattata tcgtgatgtt agatatgtct
    18241 gttagtacag cagatggtaa acaggtaacc gtgcaatttg ttcacggggt ggatgtctac
    18301 aaagaagcaa agaatatttt gcttttgtat ctcccatata catttttggt tacaattgct
    18361 ttttcctttg ttttttctta tttttatact aaacgcttgc tcaatcctct tttttacatt
    18421 tcagaagtga ctagtaaaat gcaagatttg gatgacaata ttcgttttga tgaaagtagg
    18481 aaagatgaag ttggtgaagt tggtgaagtt ggaaaacaga ttaatggtat gtatgagcac
    18541 ttgttgaagg ttattcatga gttggaaagt cgtaatgagc aaattgtaaa attgcaaaat
    18601 caaaaggttt cctttgtccg cggagcatca catgagttga aaaccccttt agccagtctt
    18661 agaattatcc tagagaatat gcagcataat attggagatt acaaagatca tccaaaatat
    18721 attgcaaaga gtataaataa gattgaccag atgagccact tattggaaga agtactggag
    18781 tcttctaaat tccaagagtg gacagagtgt cgtgagactt tgactgttaa gccagtttta
    18841 gtagatattt tatcacgtta tcaagaatta gctcattcaa taggtgttac aattgaaaat
    18901 caattgacag atgctaccag agtcgtcatg agtcttaggg cattggataa ggttttgaca
    18961 aacctgatta gtaatgcaat taaatattca gataaaaatg ggcgcgtaat catatccgag
    19021 caagatggct atctctctat caaaaataca tgtgcgcctc taagtgacca agaactagaa
    19081 catttatttg atatattcta tcattctcaa atcgtgacag ataaggatga aagttccggt
    19141 ttgggtcttt acattgtgaa taatatttta gaaagctatc aaatggatta tagttttctc
    19201 ccttatgaac acggtatgga atttaagatt agcttgtaga cagattagtt ttttattaaa
    19261 gttcatatag ggttaacata agtgtgttat tctttgtgta gataaaagaa aggatactaa
    19321 tatggtatta gcgattattt tagtaacatt ccttattcga ttgatttttt taaagcgttc
    19381 gatagagaat gagaaacgaa tccttagcaa tggcgggaaa gaatttggag ttgagaatac
    19441 aaaacgatta actatggctc atattgtttt ttatctctct tgcttggttg aggcaatggt
    19501 gcacaagaca atttttgatg gcatgggcat ggttggttta gtcttgctta ttttttctat
    19561 gctgatgtta atgttggtga ttcacttgtt gggagatatt tggacagtga agcttatgct
    19621 tgtcaataat cacaaatatg tagatcatat cttgtttagg acagtaaaac accctaatta
    19681 ctttttaaat attttacctg agttgattgg cttgaccttg ttgagtcatg cttatgtgac
    19741 ttttgtttta gtttttccag tttatgcagt tattttgtat cgacgaatag ctgaagagga
    19801 aaagctatta catgaagtta taatcccaaa tggaagcata aagagataaa tacaaaattc
    19861 gatttatata caggtcatat tgaagtgata tagtaaggtt aaagaaaaaa tatagaagga
    19921 aataaacatg tttgcatcaa aaagcgaaag aaaagtacat tattcaattc gtaaatttag
    19981 tattggagta gctagtgtag tagttgctag tcttgttatg ggaagtgtgg ttcatgcgac
    20041 agagaacgag ggaagtaccc aagtagccac ttcttctaat atggcaaaga cagaacatag
    20101 gaaagctgct gaacaattcg atgaatatat aaacaaaatg atccaattag atagaagaaa
    20161 agatacccaa aatcgcacct taatcataaa gttgagcgca attaaaacgg agtatttgcg
    20221 tgaattaaat gttttagaat ataagtcgaa agctgagttg ccgtcaaaaa taaaagcaaa
    20281 gttagacgca gcttttgatc agtttaaaaa agatacatta ccaacagaac caggaaaaaa
    20341 ggtagcagaa gctaagaaga aggttgaaga agctgagaag aaggtagcag aagctaagaa
    20401 aaaagccaag gctcaaaaag aagaagatta ccgtaactac ccaaccatta cttacaaaac
    20461 gcttgaactt gaaattgctg agttcgatgt gaaagttaaa gaagcggagc ttgaactagt
    20521 aaaaaaggaa gctgacgaat ctcgaaacga gggcacaatt aaccaagcaa aagcgaaagt
    20581 tgagagtgaa aaagctgagg ctacaaggtt aaaaaaaatc aagacagatc gtgaaaaagc
    20641 agaagaagaa gctaaacgaa gagcagatgc taagttgaag gaagctgttg aaaagaatgt
    20701 agcgacttca gagcaagata aaccaaaggg gcggagaaaa cgaggagttc ctggagagca
    20761 agcaacacct gataaaaaag aaaatgatgc gaagtcttca gattctagcg taggtgaaga
    20821 agctcttcca agcccatccc tgaaaccaga aaaaaaggtt gcagaagctg agaagaaggt
    20881 tgcagaagct gagaaaaaag ccaaggctca aaaagaagaa gatcaccgta actacccaac
    20941 caatacttac aaaacgcttg aacttgaaat tgctgagtcc gatgtgaaag ttaaagaagc
    21001 ggagcttgaa ctagtaaaag aggaagctaa ggaatctcga aacgaggaaa aagttaatca
    21061 agcaaaagcg aaagttgaga gtaaaaaagc tgaggctaca aggttagaaa aaatcaagac
    21121 agatcgtaaa aaagcagaag aagctaaacg aaaagcagca gaagaagata aagttaaaga
    21181 aaaaccagct gaacaaccac aaccagcgcc ggctcctcaa ccagaaaaac cagctccaaa
    21241 accagaaaaa ccagctccag ctccaaaacc agagaatcca gctgaacaac caaaagcaga
    21301 aaaaccagct gatcaacaag cagaagaaga ctatgctcgt agatcagaag aagaatataa
    21361 tcgcttgact caacagcaac cgccaaaaac tgaaaaacca gcacaaccat ctactccaaa
    21421 aacaggctgg aaacaagaaa acggtatgtg gtacttctac aatactgatg gttcaatggc
    21481 gacaggatgg ctccaaaaca atggctcatg gtactacctc aacagcaatg gcgctatggc
    21541 gacaggatgg ctccaaaaca atggttcatg gtactatcta aacgctaatg gttcaatggc
    21601 aacaggatgg ctccaataca atggttcatg gtactaccta aacgctaatg gttcaatggc
    21661 gacaggatgg ctccaataca atggttcatg gtactaccta aacgctaatg gtgatatggc
    21721 gacaggatgg ctccaaaaca atggctcatg gtactaccta aacgctaatg gttcaatggc
    21781 gacaggatgg ctccaataca atggttcatg gtactaccta aacgctaacg gttcaatggc
    21841 aacagattgg gtgaaagatg gagatacctg gtactatctt gaagcatcag gtgctatgaa
    21901 agcaagccaa tggttcaaag tatcagataa atggtactat gtcaatggct caggtgccct
    21961 tgcagtcaac acaactgtag atagctatag agtcaatgcc aatggtgaat gggtaaacta
    22021 aacctaatat aactagttaa tactgacttc ctgtaagaac tctttaaagt attccctaca
    22081 aataccatat cctttcagta gataatatac ccttgtagga agtttagatt aaaaaataac
    22141 tctgtaatct ctagctggat ttatagcgct agagactacg gagttttttt gatgaggaaa
    22201 gaatggcggc attcaagagg ctctttaaga gagttacggg ttttaaacta ttaagccttc
    22261 tccaattgca agagggcttc aatctctgcc agggtgctag cttgcgaaat ggctccacgg
    22321 agtttggcag cgccagatgt tccacggaga tagtgaggag cgaggccgcg gaattcacga
    22381 actgcgacgt tttctccttt gaggtcaatc aatcgtttca agtgttcgta ggcgatcttc
    22441 atcttgtctt caaaggtcaa atcaggtagg atttctcctg tttcaaagta atggttgatt
    22501 tggttgaaga ggtaaggatt tcccatggca gctcggccaa tcatgactgc gtcagcacca
    22561 acttcttcga tgcgttgctt ggcttcttgg acagtacgga tatcaccgtt ggcgatgaat
    22621 ggaatcttgg ttagagcttg ggcaaccttg taaagggtct caaggtctgc gtggccagta
    22681 tacatttgtt cacgggtacg gccatgcatg gcgagggcag aaacacctgc agcttcagca
    22741 gcgagagcat tttctactgc aagagatggg tccgcccagc cggtacgcat tttgacagta
    22801 agtgggatat caaggacaga ctggaccttg ttgatgatag agtagatctt gtcaggatcc
    22861 ttgagccaca tagcaccagc ttcgttcttc acgattttgt tgacagggca gcccatgttg
    22921 atatcgacga tatcggtctt ggtgttttct tggataaatt ctgctgcgcg tgctaggctg
    22981 tcttcatcgc taccaaaaag ttggatagag acagggtttt cgccctcatc gatatgaagc
    23041 atgtgcaggg ttttttcgtt gttgtattgg attcccttgt cagagaccat ttccattaca
    23101 acgagtccag ctccgagctc ttttgcgatg gtacgaaagg ctgagttggt cacgccagcc
    23161 ataggcgcta aaacggtacg attgggaatc tcaacattgc caatcataaa aggtgtatta
    23221 agatttgtca cgaatgagtt cctccaggtc cttttcatca aagttgtaag tagtttggca
    23281 gaattgacaa gtgatttcta ccccgtggtc ttcctctttc atttcctgta agtctgagct
    23341 tggaaggctg gcaagagcgt tcataaagcg ttcatggcta cagtcacatt ggaaacggat
    23401 ttcttcttca gaaagacgct tgtaggcttc gtccccgtag atagccttga ggagggcttc
    23461 gatatggtcg tcgctttcga gaagagtaga gatagctggc atttcttgga tgcgtttttc
    23521 aaagcgagca atctcttctt tcttggctcc tggcaagact tgaactagga aaccacctgc
    23581 aatcttgacc ttgtcttcct cgtccaaaag gacattgagg ccgaccgctg aaggcgtttg
    23641 ttggctttca gtaaggtaaa aggcaaggtc ttcaccgatt tctccagaga tgaggggagt
    23701 tatagagttg taaggatttc cagtaccgta gtctgtgata acgaggaatt gaccatttcc
    23761 aacaaaaggt ccgactagga cttcaccagt cgcagtcttt ttgatgtcaa caccaggatt
    23821 ttgaacgtag cctttgacgt tccccttggt atcagcgacg gtgataatag cacctagaga
    23881 gctagatccc aacaccttaa ctgtaagttt ggtatttcct ttttcattgg ctgcgagaat
    23941 ctggctggcg ataagagttc gaccaagcgc tacagttgag ctagcttggg tttgatgttt
    24001 ttcttgagca gtgcggacgg tttcagtgct atcaaggaca aaagcacgaa aggctccgct
    24061 ttctgatata gttttaataa ttttatccat agctactatt ttagcataaa aatgcccaaa
    24121 gggggagccg tgtgtttact gattttcagg ataatggacc aggaaatcag catgaaaata
    24181 aaaagagaaa cagattattt tagcatttgt aagatttatg ctatgcttaa ggtagaaaat
    24241 gaaaggggta acaaatgtat ttaggagatt tgatggagaa agccgagtgt ggtcaatttt
    24301 caatcctttc ctttctatta caagagtctc agacgaccgt caaggctgta atggaagaaa
    24361 caggattttc aaaagcaacc ctaaccaaat atgtcaccct gctcaatgac aaggctttgg
    24421 atagtggctt agagctggct attcactcag aagatgaaaa tctgcgtctg tctatcggtg
    24481 cagctaccaa ggggagagat attcggagct tgtttttgga gagtgctgtt aaataccaga
    24541 ttttggttta tcttctctac caccaacagt ttttagccca tcagctggct caagaattgg
    24601 tgattagcga ggctacgctt ggtcgtcact tggctggttt aaatcagatt ttgtcagaat
    24661 ttgatttatc catccaaaat ggacgttggc gaggtccaga gcatcagatt cgctatttct
    24721 atttctgtct tttccgaaag gtctggtcga gtcaggaatg ggaaggtcac atgcagaaac
    24781 cagagagaaa acaggagatt gccaatttag aggaaatctg cggtgcaagt ttgtctgtgg
    24841 ggcagaaatt ggacttggtt ctctgggctc acatcagtca acaacgtctt cgggtcaatg
    24901 cttgtcagtt tcaagtcata gaagagaaaa tgcgagggta ttttgacaat atcttttatc
    24961 ttcgtttgct gagaaaggtt ccgtcctttt ttgctgggca acatattcca ctaggagttg
    25021 aggatggtga gatgatgata ttcttctctt ttctcctatc tcatcgcatt cttcctcttc
    25081 atactatgga gtatattctt ggttttggag ggcagttggc agatttactg acgcaattga
    25141 ttcaagaaat gaagaaggag gaactattgg gggattatac agaggaccat gtcacctatg
    25201 aactcagtca gctttgtgct caagtctatc tctataaggg ctatatttta caggatcgct
    25261 acaagtacca gttagagaat cgtcatccat atttactgat ggaacatgat tttaaagaga
    25321 cagcagagga gatttttcat gctctaccta cttttcaaca ggggacagat ttagataaga
    25381 agattctctg ggaatggctc cagttaatcg aatatatggc tgaaaacggt ggccagcata
    25441 tgcggattgg tctggatttg acatctggtt ttcttgtctt ttcaaggatg gcagccattt
    25501 tgaaacggta tttggaatac aatcgtttta ttaccattga agcctatgac cctagtcggc
    25561 attatgattt gctggttacc aataacccta ttcataagaa ggaacagaca ccagtctatt
    25621 atttaaaaaa tgacttggat atggaagatt tggcagggat tcgtcagtta ttattcactt
    25681 aaaaggcttg gttaatccag gtcttttttg tgaaattcac acaatctcct cacatttttt
    25741 taaaaattaa aaaaagttga taaacaagaa agcgctttat tttgtatact agtaagtgta
    25801 aagaggaaac acctcaagat ctttatcagg aggacagtac atgtcacaag aaaaatacat
    25861 catggccatt gaccagggaa ctacaagttc tcgtgccatc attttcaaca aaaaagggga
    25921 aaaggttagc tcgagtcaaa aagagtttac ccagattttc cctcaggcag gttgggttga
    25981 gcacaatgcc aatgaaattt ggaactctgt tcagtcagtt attgcgggtg ctttcatcga
    26041 aagtggtgtc aagccaaatc aaatcgaggc aatcgggatt accaaccaac gtgaaacaac
    26101 ggttgtctgg gataagaaaa caggacttcc tatctacaat gctatcgttt ggcagtcacg
    26161 ccagacagca cctttggctg agcaactaaa aagccaaggt tatgtggaaa aattccatga
    26221 aaagactggt ttgattattg atgcttactt ctctgctacc aaggttcgtt ggattttgga
    26281 tcatgtagaa ggtgctcaag agcgagcaga aaaaggggaa ttgctctttg gtactatcga
    26341 tacttggttg gtttggaaat tgactgacgg tgcggctcac gtgactgact actcaaatgc
    26401 agctcgtacc atgctttata acattaaaga actcaaatgg gatgatgaga ttttggaaat
    26461 ccttaacatt ccgaaggcta tacttccaga agttcgttct aactccgaaa tctacggcaa
    26521 gacagctcca ttccatttct acggtggaga ggtgccaatc tcaggtatgg ctggggacca
    26581 acaagcagcc ctctttggac agttggcttt tgagccaggt atgattaaga atacttatgg
    26641 aacaggctct ttcatcatca tgaatactgg ggaagagatg cagttgtctg aaaacaacct
    26701 cttgacaacc attggttacg gaatcaacgg taaggtttat tatgccttgg aaggttctat
    26761 cttcatcgca ggaagtgcta ttcagtggct tcgtgacggt cttcgcatgg ttgaaaattc
    26821 accagaatct gaaaaatacg ctcgtgattc tcacaacaac gatgaagttt atgtcgttcc
    26881 agcctttaca ggtctaggcg ctccatactg gaaccaaaat gctcgtggtt ccgtctttgg
    26941 tttgactcgt ggaacaagca aagaagactt tatcaaggcg actttgcaat ctattgctta
    27001 tcaagtgcgt gacatcatcg acaccatgca agtggatact cagaccgcca ttcaagtatt
    27061 gaaggtggat ggtggtgcag ccatgaacaa cttcctcatg cagttccagg cggatatttt
    27121 aggcattgat attgcacgtg ctaaaaactt ggaaacaaca gctctaggag cggccttcct
    27181 agcaggtttg tcagtagggt actggaaaga cttggacgag ttgaaactct tgaacgagac
    27241 aggagaactc tttgagccat ctatgaacga atctcgcaag gaacaactct acaagggctg
    27301 gaagaaggct gtgaaagcaa ctcaagtctt tgcggaagta gacgactaat actggcagaa
    27361 taaagcgatt tatttagaaa gtgtgtaaat atggaatttt caaagaaaac acgtgaattg
    27421 tcaattaaaa aaatgcagga acgcaccctg gacctcttga ttatcggtgg aggaatcaca
    27481 ggagctggtg tagccttgca ggcggcagct agcggtcttg agactggttt gattgaaatg
    27541 caagactttg cagaaggaac atctagtcgt tcaacaaaat tggttcacgg aggacttcgt
    27601 tacctcaaac aatttgacgt agaagtggtc tcagatacgg tttctgaacg tgcagtggtt
    27661 caacaaatcg ctccacacat tccaaaacca gatccaatgc tcttaccagt ttacgatgaa
    27721 gatggagcaa cctttagcct cttccgtctt aaagtagcca tggacttgta cgacctcttg
    27781 gcaggtgtta gcaacacacc aactgcgaac aaggttttga gcaagaaaga agtcttggaa
    27841 cgccagccaa acttgaagaa ggaaggcttg gtaggaggtg gagtgtatct tgacttccgt
    27901 aacaacgatg cgcgtctcgt gattgaaaac atcaaacgtg ccaaccaaga cggtgccctc
    27961 attgccaacc acgtgaaggc agaaggcttc ctctttgacg aaagtggcaa gattacaggt
    28021 gttgtagctc gtgatctctt gacagaccaa gtatttgaaa tcaaggcccg tctggttatt
    28081 aatacaacag gtccttggag tgataaagta cgtaatttgt ctaataaggg aacgcaattc
    28141 tcacaaatgc gcccaactaa gggagttcac ttggtagtgg attcaagcaa aatcaaggtt
    28201 tcacagccag tttacttcga cacaggtttg ggtgacggtc gtatggtctt tgttctccca
    28261 cgtgaaaaca agacttactt tggtacaact gatacagact acacaggtga tttggagcat
    28321 ccaaaagtaa ctcaagaaga tgtagattat ctacttggca ttgtcaacaa ccgctttcca
    28381 gaatccaaca tcaccattga tgatatcgaa agcagctggg caggtcttcg tccattgatt
    28441 gcagggaaca gtgcctctga ctataatggt ggaaataacg gtaccatcag tgatgaaagc
    28501 tttgacaact tgattgcgac tgttgaatct tatctctcca aagaaaaaac acgtgaagat
    28561 gttgagtctg ctgtcagcaa gcttgaaagt agcacatctg agaaatattt ggatccatct
    28621 gcagtttctc gtgggtctag cttggaccgt gatgacaatg gtcttttgac tcttgctggc
    28681 ggtaaaatca cagactaccg taagatggct gaaggagcta tggagcgcgt ggttgacatc
    28741 ctcaaagcag aatttgaccg tagctttaaa ttgatcaatt ctaaaactta ccctgtttca
    28801 ggtggagaat tgaacccagc aaatgtggat tcagaaatcg aagcctttgc gcaacttgga
    28861 gtatcacgtg gtttggatag caaggaagct cactatctgg caaatcttta cggttcaaat
    28921 gcaccgaaag tctttgcact tgctcacagc ttggaacaag cgccaggact cagcttggca
    28981 gatactttgt cccttcacta tgcaatgcgc aacgagttgg ctcttagccc agttgacttc
    29041 cttcttcgtc gtaccaacca tatgctcttt atgcgtgata gcttggatag catcgttgag
    29101 ccagttttgg atgaaatggg acgattctat gactggacag aagaagaaaa agcaacttac
    29161 cgtgctgatg tcgaagcagc tctcgctaac aacgatttag cagaattaaa aaattaagaa
    29221 aaaataaaag aggtggaggg cagcattcct tgtcgcccgc cccttctttt taatggagac
    29281 agaaagatga tgaatgaatt atttggagaa tttctaggga ctttaatcct gattcttcta
    29341 ggaaatggtg ttgttgcagg tgtggttctt cctaaaacca agagcaatag ctcaggttgg
    29401 attgtgatta ctatgggttg ggggattgca gttgcggttg cagtctttgt atctggcaag
    29461 ctcagtccag ctcatttaaa cccagctgtg accatcggtg tggccttaaa aggtggtttg
    29521 ccttgggctt ccgttttgcc ttatatctta gcccagttcg caggggccat gctgggtcag
    29581 attttggttt ggttgcaatt caaacctcac tatgaggcag aagaaaatgc aggcaatatc
    29641 ctggcaacct tcagtactgg accagccatc aaggatactg tatcaaactt gattagcgaa
    29701 atccttggaa cctttgtttt ggtgttgaca atctttgctt tgggtcttta cgattttcag
    29761 gcaggtatcg gaacctttgc agtgggaact ttgattgtcg gtatcggtct atcactaggt
    29821 gggacaacag gttatgcctt gaacccagct cgtgaccttg gacctcgtat catgcacagc
    29881 atcttgccaa ttccaaacaa gggagacgga gactggtctt acgcttggat tcctgttgta
    29941 ggccctgtta tcggagcagc cttggcagtg cttgtattct cacttttcta gtt
//
LOCUS       DBEROT010000029        28348 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.29, whole genome shotgun sequence.
ACCESSION   DBEROT010000029 DBEROT010000000
VERSION     DBEROT010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 28348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28348
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.29"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(94..252)
                     /locus_tag="ACL8CG_001429"
     CDS             complement(94..252)
                     /locus_tag="ACL8CG_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344009.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(262..1572)
                     /gene="obgE"
                     /locus_tag="ACL8CG_001430"
     CDS             complement(262..1572)
                     /gene="obgE"
                     /locus_tag="ACL8CG_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGS1344010.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(1636..1770)
                     /locus_tag="ACL8CG_001431"
     CDS             complement(1636..1770)
                     /locus_tag="ACL8CG_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGS1344011.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(1829..2005)
                     /locus_tag="ACL8CG_001432"
     CDS             complement(1829..2005)
                     /locus_tag="ACL8CG_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS1344012.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(2036..3361)
                     /locus_tag="ACL8CG_001433"
     CDS             complement(2036..3361)
                     /locus_tag="ACL8CG_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1344013.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(3377..4420)
                     /gene="cpoA"
                     /locus_tag="ACL8CG_001434"
     CDS             complement(3377..4420)
                     /gene="cpoA"
                     /locus_tag="ACL8CG_001434"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGS1344014.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(4535..4864)
                     /locus_tag="ACL8CG_001435"
     CDS             complement(4535..4864)
                     /locus_tag="ACL8CG_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS1344015.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(4878..5987)
                     /gene="rpoD"
                     /locus_tag="ACL8CG_001436"
     CDS             complement(4878..5987)
                     /gene="rpoD"
                     /locus_tag="ACL8CG_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGS1344016.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(5990..7750)
                     /gene="dnaG"
                     /locus_tag="ACL8CG_001437"
     CDS             complement(5990..7750)
                     /gene="dnaG"
                     /locus_tag="ACL8CG_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGS1344017.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(7840..8598)
                     /locus_tag="ACL8CG_001438"
     CDS             complement(7840..8598)
                     /locus_tag="ACL8CG_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344018.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            complement(8595..9461)
                     /locus_tag="ACL8CG_001439"
     CDS             complement(8595..9461)
                     /locus_tag="ACL8CG_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344019.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(9530..10534)
                     /gene="trpX"
                     /locus_tag="ACL8CG_001440"
     CDS             complement(9530..10534)
                     /gene="trpX"
                     /locus_tag="ACL8CG_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1344020.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(10647..10864)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10947..13643)
                     /gene="ppc"
                     /locus_tag="ACL8CG_001441"
     CDS             complement(10947..13643)
                     /gene="ppc"
                     /locus_tag="ACL8CG_001441"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGS1344021.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTTIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(13663..14892)
                     /locus_tag="ACL8CG_001442"
     CDS             complement(13663..14892)
                     /locus_tag="ACL8CG_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS1344022.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGLSVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(15020..15349)
                     /locus_tag="ACL8CG_001443"
                     /pseudo
     CDS             complement(15020..15349)
                     /locus_tag="ACL8CG_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(15454..15702)
                     /locus_tag="ACL8CG_001444"
     CDS             complement(15454..15702)
                     /locus_tag="ACL8CG_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HGS1344023.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILAYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            complement(15984..16592)
                     /locus_tag="ACL8CG_001445"
     CDS             complement(15984..16592)
                     /locus_tag="ACL8CG_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HGS1344024.1"
                     /translation="MKEQIFLMGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEP
                     YMKKYTEVFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEF
                     KSYIDYMLNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHY
                     DSWNDKANKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            complement(16676..18469)
                     /locus_tag="ACL8CG_001446"
     CDS             complement(16676..18469)
                     /locus_tag="ACL8CG_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGS1344025.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSFDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
     gene            complement(18636..18788)
                     /locus_tag="ACL8CG_001447"
     CDS             complement(18636..18788)
                     /locus_tag="ACL8CG_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344026.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            complement(18919..19122)
                     /locus_tag="ACL8CG_001448"
     CDS             complement(18919..19122)
                     /locus_tag="ACL8CG_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1344027.1"
                     /translation="MYIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSF
                     LKQLAKLYQVTTDYILEMDKFSC"
     gene            19624..20819
                     /locus_tag="ACL8CG_001449"
                     /pseudo
     CDS             19624..20819
                     /locus_tag="ACL8CG_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(21198..21983)
                     /locus_tag="ACL8CG_001450"
     CDS             complement(21198..21983)
                     /locus_tag="ACL8CG_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344028.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDGLFNIGGLILISLIFFTLSLKLWNKGLDAYESAGS"
     gene            complement(21985..22803)
                     /locus_tag="ACL8CG_001451"
     CDS             complement(21985..22803)
                     /locus_tag="ACL8CG_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344029.1"
                     /translation="MTKLWKRYKPFVSAGIQELITYRVNFFLYRIGDVMGAFVAFYLW
                     KAVFDSSHQSLIQGFTLSDMTLYIIMSFVTNLLTKSDSSFMIGWEVKDGSIIMRLLRP
                     VHFAMSYLFTEIGSRWLVFVSVGLPFVILIAGLKLLSGESFLQIVLITTVYLLSLILA
                     FLINFFFNICFGFSAFVFKNLWGSNLLKNSLVAFLSGSLVPLTFFPKIIAELLSFLPF
                     SSLIYTPVMVIIEKYSMSQMIQALSLQLFWLFIMIALSQLIWKCVQNYITIQGG"
     gene            complement(22805..23797)
                     /locus_tag="ACL8CG_001452"
     CDS             complement(22805..23797)
                     /locus_tag="ACL8CG_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1344030.1"
                     /translation="MKMITVEHLQKNFVKTIKEPGLKGAFRSFFHPKRQVFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQENRQGYVKDIGVV
                     FGQRTQLWWDLALQETYSVLKEIYDVPDAVFQKRMDFLNEVLDLKEFIQDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLG
                     DIEQLCDRIFMIDKGREIFDGTVNQLKKTFGKMKTLSFELHPGQDYIVSHFEGLSDIY
                     VTRQELSLDIQYDSSQYQTADIIQQTLSDFTIRDLKMTDANIEDIIRRFYRKEL"
     gene            complement(24814..25605)
                     /locus_tag="ACL8CG_001453"
                     /pseudo
     CDS             complement(24814..25605)
                     /locus_tag="ACL8CG_001453"
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
     gene            complement(25682..27319)
                     /gene="metG"
                     /locus_tag="ACL8CG_001454"
     CDS             complement(25682..27319)
                     /gene="metG"
                     /locus_tag="ACL8CG_001454"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGS1344031.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKF
                     YDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWN
                     YISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            complement(27387..28061)
                     /locus_tag="ACL8CG_001455"
     CDS             complement(27387..28061)
                     /locus_tag="ACL8CG_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatA-like O-acetyltransferase"
                     /protein_id="HGS1344032.1"
                     /translation="MLHPIFIIRRSWDGIFHLSEWKRNEEFDFFNKMDVPYLSMSSRI
                     EVTQAINFHKKHSISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTS
                     EDKLNFSSFTMGDNLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVST
                     PMNLSKIDTVPRITWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKIN
                     EYFQKK"
     gene            complement(28120..>28348)
                     /locus_tag="ACL8CG_001456"
     CDS             complement(28120..>28348)
                     /locus_tag="ACL8CG_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344033.1"
                     /translation="DSTGGGKRLNTSIRSAYSGSDITPVYSLGSGSRIVMYYNGGGDN
                     YIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
BASE COUNT         8786 a         5947 c         4531 g         9084 t
ORIGIN      
        1 atcaaaaaag aaaggacaaa atttgtcctt tctcaagctt agcttttttt caacccacta
       61 cagttgacaa agagccggga ttttttagct tctttactga gatggatttt cctttttagt
      121 tcgtgccaat ctcaaggcac gatttggatt gagacgatta aatagttctt ccaatttctt
      181 ttcattccaa acgtctgcgg cggaaacaaa attaccatcc gcatctcgga aagatatcgg
      241 tttatctccc ataccagtct cctagtctac aaattcaaac tcaaatttac caatgcggac
      301 caaatcccca tctttagctc cacgcgcacg aagggcttca tcaaccccca taccacgaag
      361 ctgacgggca aatttcatga cagattcatc acgatcaaag ttggtcatat taaagagttt
      421 catgagtttt tcaccagaaa gtacccatgt cgcatcgtca tcacgactaa tttcaaaggc
      481 tttttcttct tcgtcaaatc catagtaagc ttcttcttcc atatcggact cgtcgtagag
      541 caaaaattct ggtgtcttgt ctaacaattc agctgtagca tctaaaagtg ttgccagacc
      601 ttgcttggtc aatccagaaa ttgggaagat agctggtaac tcttcaaatt catcataatt
      661 ttcagacaat tttttcttaa attcttcaag attttcctga ctctcaggca tatccatctt
      721 attagctaca ataatctgtg gacgctccat gaggcgaaga ttgtaagact ccagctcttt
      781 attgatagct aggtaatcct catatggatc acggccttcg ctagctgaca tatcaatgat
      841 gtgaaggata acacgtgtac gctcgatgtg acggagaaac tgagttccca aaccaacacc
      901 ttgactagcc ccttcaatca aacctggcaa gtcggctact gcaaaggatt cacctgattg
      961 ggtgcgaacc atacctaaat ttggtacaat agtggtaaag tggtaggcac caattttagg
     1021 cttagctgag gtaataacac ttaaaagtgt tgacttccct acagatggga atcctactaa
     1081 accgacatct gccaagattt ttagttccaa ttgtaactca cgttcctgac ctggttctcc
     1141 attttcagag atttccggtg caggattttt tggtgtcgcg aaacgaatat ttccacgtcc
     1201 accacgacca ccgtgggcaa cgataaattc ttgcccatgt tcaatcaaat ctgttaaaac
     1261 cttgccagtc tccgcatcac gaacagtcgt accttgtggt actcgaactc taaggtcctc
     1321 agcaccacga ccatgcatcc ctttggtcat ccctttttca ccagaatcag ccttgaaatg
     1381 acgattgtag cggaaatcca tcaaggtacg tagtccttcg tctacaacga agaccacatt
     1441 gcctccacga ccaccatcac caccccaagg gcctccatta gggacatatt tttcacgacg
     1501 aaaggcaacc ataccatcgc caccattacc agccttgacc ttaatcttag ctgtatctaa
     1561 aaacatactc attatttctt ctcactttaa aaaagggctg ggaaatccca gtcactaaat
     1621 tttcttgaat ctattttata gattactgag ggcaccaatt gcagttgcaa aaattcccaa
     1681 taaacttgct actagcatga taatcacgat aaacaaggtt attttctcaa acatagtttt
     1741 tttacgattt ccattatctc caaatgccat ttttctctcc ttcgttacat tctattttct
     1801 attatcttag catgaattga gctagttttc aatagtcagt tgctactggt gcgataatcc
     1861 ataaaataat gtaagctaca attccagctc cgtaacagca agtaagaaca ccccaaatga
     1921 cttgaacgat agtcggatcc atatccagat aatgggccac cccagcacaa acacccgcaa
     1981 tctttttatc acgaccgctt ctcattaatt gtttttttca tagctgttcc tctttctatt
     2041 cttcatggtc tttccaatag tctctcatac tgatcaactg tgtttttgaa gccttcaaca
     2101 tgcgtctaga tccttttaca ggtacagcaa ccacctgttg ctgaagatac aaaactgtct
     2161 taaagatacg ctgactgacc gtatcatctt tagccaaatc tttctggaag ttatttgaaa
     2221 taatggcatc cagataaaac tcatgcactc gtttcccaaa gttctcagct gaaatctcat
     2281 acaatttctc tgataaggta tgctcgttca tgtctggtgt tgcaatcagg gcttccaaaa
     2341 tagcaccagc caaatcatgt tctccatagt acaaggttcc aaacatttta tcactgatga
     2401 ggttgttcaa ataaggattt ccgtgagcaa tgacaggtgt tccactggct aagctttcca
     2461 agtaggtcaa accttgcgtt tcgcttgtcg atgccgaaat gaaaaaatcc gccgctttat
     2521 agtaaagagc cgtctcacta ggagcaatca tccctgtaaa gatgactgag tcttgaatct
     2581 ctaggttctg ggcttgctct ttgaggtcat tcagataagg gccatcccca gctactacca
     2641 gtttaacctt gtcttcctct ttcagaacat cagcaaaggc tactaaaact gcttgaatat
     2701 ttttttcata ggagattctc gaaagactaa gcaacgtctt ttcaccatct tgaatcccta
     2761 gtttactacg cagttctttc aaattttcct gcttgatttc cggacgctca aacttggcta
     2821 attcaatccc agtaggaatg acccgttttt caaccttgac cttataatca gatagcaagt
     2881 cacggacaat ctcactaggg caaataaccc catccacatc atgcaggaaa cctctaacca
     2941 gatacttgac catactcggt cggatcaaca tccccttagc aatataatgg acatagtctt
     3001 catactgggt gtgataggta tggatgactg gaattttcaa ttcacgcgca atccaaatcc
     3061 ccaacaggcc aagagaaaat tctgtctgag tatggataat atctagctga tactgtttag
     3121 caatttcaag tgccttgcta aaacctcggt aggcaaagcg acgatcctta aaagcaaaga
     3181 aaggaacact tggaatgcgg ataatttgcc aatcttcgta gcgattgaca tccttatctg
     3241 tcgtcgtaaa gataaaaaca gcatgtccct gcttttcaag ttctgttttc aaggttcgaa
     3301 tactggtcgc aacaccagaa acctgaggaa aataggtatc tgtaaataaa ccaattcgca
     3361 tagattacct cactttttac tttctcccta aagcggcttg tttctcataa aagtccaacc
     3421 agatttgtaa cagatgctct tcagaatact ctctggaaat attcttagcc ttttctttga
     3481 gatcttttaa ggcagcagga tttgcttgat attccaaaat agcctctttc atctcttctc
     3541 tacccgctgt cgcccgataa tttccctcca aaatcacctt atagagatct aaatcacgca
     3601 acataatagg agcctcacaa ctcgcagctt ctaaaatagt cataggaaag agctcattgt
     3661 aactaggcaa caagaaaaga tccgctagag catacaattc gcgcatccgc tctggcgata
     3721 caatgcctgg aaaaatcaaa tttttagggg gattttccat aattttctta tagtgttcat
     3781 aaccatctgt cataccacca aaagagaagc caccagccca gataaaggta atctgaggca
     3841 attcctcagc cagacggata aagtcatcaa tccctttacg tttctgaact tgcccagcac
     3901 ctactacgat aaactgattg tcactaagac caagatctgt gcgcagtctg actacctctt
     3961 cttgtggtag aggatgccat ttttccttgt tgacaaagtt aggaatatag gtcacttttt
     4021 cacgtggaat accagctgct accaaatcct caataaacat aggattgacc acaaccaagt
     4081 gctccatccg gttgtaaaaa gaaaatacat agcgtttcac aattcccttt aagaaaaatg
     4141 gaattttcaa acttccctca agtgtagctg gcaagaaatg cacatagcca atctttctcc
     4201 ctgagcgttt cttttggaag gttgataaat aatagggaaa atcaatcgta tgaaagtgag
     4261 tcacatctgc ctcgatcgga agattttctg taacaatcaa ttggtccttg gcagcacggt
     4321 gaagaagacg aactaattca cggtaagcac ctgaaactcc ctgtcctgct actttctcac
     4381 ttgaactcaa catattgatg cgtaatttct ttttctccat aactactatt atatcatttt
     4441 ctttgaataa aatcagcaaa agaaaggaga gactagagga aaagagggga aatttcctcg
     4501 cttttccaac agtctctcac atgcttttat atgtttactt aatgcctagg gcaatgcggg
     4561 catagcgact cattttttca actgtccagg ctggatacca gactaattta acctcagtat
     4621 ccgttacttc tggaacctct atcatagcat cataaatctg gtctgtcaaa aggtctgcta
     4681 agggacaacc catagttgtc aaagtcatgt caatctctgt ttgccctgtg tcaccgtcaa
     4741 aacgaatctc atagatcaaa ccaagattga caatatcgat tcccaactca gggtcgatga
     4801 cttcttccaa ggctgttaaa atccgtgttt tgatgttttc aatttgctct tctgtataag
     4861 ccatattttc ctcactctta gtcttcaata aaatcacgaa gcggtttgct gcgacttggt
     4921 tggcgtagtt ttctcaaagc ctttgcttca atctgacgga tacgctcacg agttacgtta
     4981 aagactttcc ccacatcttc aagtgtgcgc atttttccat catctagtcc aaaacgtaga
     5041 cgcagaacat tttcttcacg gtctgtaaga gtatctaaga tttcatccaa ttgctcacgc
     5101 aagacgatac gagtcgtata atccactgga ttttcaatca cttcatcttc gataaagtct
     5161 ccaaggtggc tatcgtcctc ttcaccgata ggagtttcaa gagatactgg ttcttgggca
     5221 atcttcaaga tttcacgaac cttatcaggt gtcatatcca ttcgttcagc aatctgttct
     5281 ggtgtcggat cttgccccaa ttcttgaagg agattccgct gttcacgaac caatttattg
     5341 atagtttcaa ccatgtgaac tgggatacgg atggtacgag cttggtccgc aatagcacga
     5401 gtgatagcct gacgaatcca ccaagttgca taagttgaaa acttgaaccc tttagaatag
     5461 tcaaacttgt caaccgcctt catcaagccc atatttcctt cttgaatcaa gtcaaggaac
     5521 tgcataccac gaccgacata gcgtttggca atggaaacaa ccaaacgaag attggcttcc
     5581 gcaagacgtt gtttggcttc gatatcacca gcttcaacag ccagtgccaa ctctttctcc
     5641 tcttcattgg tcaagagagg aacgacccct atttctttca agtacatacg gacagggtca
     5701 ttgaccttag cagaagttga cccaatcaag tcctcatcgc tgagttctgg ttcttcttca
     5761 ttgctgagaa cacgcgcact tggatttcct tcgttatctg tgatagaaat gcctgcatcc
     5821 tgaatccgtt gcaagagatc ttcaatccca tcagcgtcca aggtaaaagg aataaccaga
     5881 cttgcattga tttcatcatc tgttgctgtc cctttttgct tatgattacg gataaattct
     5941 gctacctgta cgtcaaatgt tgttacttct ttttgttttg ttgccattat tactccattc
     6001 ttctcttttg ggaaattaaa cgttccaatt cttctagggc tgtatctgta tctcctacat
     6061 ggctagcttc ctgcaccttc tttttgattc tcatattgtc ctgattcaag agagccttgt
     6121 ttcgagtcat ctctacttca ctaagttcct gcggcgatat ctcagcaggc aaatcctgag
     6181 ctaaaacttg gtaccaagct ctttcaactt cctctgtctg ctctgctaaa acttctggag
     6241 gaagatttcc atactggcca agcaagtcat ataagacctg aaattcaggt gtagcaaatg
     6301 caaagtcttc tcgcaaacgg taatcgttca aaacaagagg ggattccatc atccgataga
     6361 gtagatgggc ttctgccctc ataatagccg ataactgctt ggtgacaggc atggtgattg
     6421 gcgtcggtct ggaaattctt tccatgcgat tctgcctttg cacctgacga ctctcattaa
     6481 caatctgctc aatctgggta taatcaaagg acgccagact gtcagctaaa atatgaatat
     6541 agctgttttg agcagcgatg gacttttctt gaacaatcaa gggagctatt ttttcaataa
     6601 actcaatctg agcctgcaga ttttcactgt tttcaggttt gtactgatga atgtagaact
     6661 caatcggact aatacgagtt tttgttaata gataggccaa gtcttctgga ccattttttt
     6721 gtagatactc atcaggatcc aagttatcag gcatgctaac gatttgcaca ggcatatcac
     6781 caatttcatc caatgctttc aatgtcgcgg cttgcccagc cttatctcca tcgtaaacaa
     6841 gaaccaattt cttggttaac cttttcagat gctcaacatg ctctcgactc aaggccgttc
     6901 ccatcgacgc cacagcattt tcgattccag cccgataggc tgcaataaca tccatgaatc
     6961 cttccatcag gtaaatctca ctagtttttc cagaagattt ttttgcccta tccatatgat
     7021 ataattcgta acttttgtta aaaattgcag tcgatcggct gtttttatac ttagaagttt
     7081 gtgaatctgt tttttgccag atacgacctg agaaggcaat gacctttcct tggtcatttg
     7141 tcaggggaaa cataatgcga ttgtgaaagg tgtctacaaa ttgattggca tccgagagat
     7201 aaaacaggcc tgaatccagt aaatcttctt cacgatactg atcagacaaa cgttgataga
     7261 gatagtttcg ttctggaggt gctaaaccaa tccaaaaatg tttaagcact tcatctgtca
     7321 aaccccgctg ataaaggtaa tttctggcct cttcgcccat agtcgttgtc atgagaatag
     7381 catggtaaaa tttagccgca tcttcgtgca tatcataaag agcttggtga ggcgaggctg
     7441 gcttctgttc actataaagc ggtttttcaa cctcaatccc gacacgctga cctaagattt
     7501 ggacagcctc cataaaggta accccttggt actcctcgat gaatttaaag acatcacctg
     7561 agcgaccaca accaaaacag tggtaaaact gcttgtcctc tacaacgttg aaagaaggtg
     7621 ttttttcacc atgaaaagga cagagcccta gatagttccg tcctgccttt tgtaaagaaa
     7681 tcacatctcc tatgacttcc acaatgttgg cattgttttt gatttcttca atgacttgtt
     7741 tgtcaaccat acacaatacc tccatgttat catagtttac tttatatagt atactttatt
     7801 tcagaaaaaa agtaaaccat ttcactcatt ttccctactt tattcaaaga gttgataata
     7861 atcagagatt ttcatttttg ctttttcttc ttgtttcaaa tcttggataa cccgtccttc
     7921 tttcatgaca atcaagcgat tgccatattt gagagcatct tccatatgat gggtaatcat
     7981 aagggctgtc aattgatctt tcttaacaaa ttcatctgtc aattccatca aagcaacact
     8041 agtctttgga tccagggcag cagtatgctc gtctaacaag agtaattcag gtcgcttcaa
     8101 ggttgccatc aagagactca aagcctgtct ttgtccacca gataagaact caatcggtgt
     8161 attcaagtgt ttctcaagac cgtttcccac tttttcaatg gtcgcctgaa acttatcctt
     8221 atagctagcc agacgtctcg gaaatagtcc acgcttttca ccacgaaact tggcaatcag
     8281 gagattctct gccactgtca tacgaggagc tgtccccatc tttggatctt ggaagactcg
     8341 agacagatac ttagcgcgct tctctggtga aaacttggta acatcctcac ctaaaatacg
     8401 gatagttcca ctggttagtg atatggttcc tgcaatagtg ttaaagaggg ttgatttacc
     8461 agcaccattt ccacccaaaa tcgtgataaa gtcctgttca aaaatttcta aggaaacatc
     8521 atttaaaata atcttttctt catcaaagcc atttttaacg attttggttg cattttttaa
     8581 ttctacaatt gctgtcattt gcttaacttg gctcctttca agattgtttg cttaaatgtt
     8641 ggaatcatga ggcagactgc taaaatcaag gcactgtata aacgaaggta acttgtatta
     8701 aagccaagtg cgataactgc ccacactaaa aattgataag cgatagaacc tacaacgata
     8761 gtaaccaaac gctctgccaa gctcaaactc ttgaaaataa cttctccaat aatcaaactt
     8821 gcaagcccca caacgataac cccgatccct cgagacacat cggcataacc ttcttgctga
     8881 gcaatgaggg cacctgcaag ggcaatcaca ccatttgata agaccaagcc catgagctcc
     8941 atgtgtccag tatgaatccc gaaacttcta gccatatcag gattatcccc tgtagcaata
     9001 taggcttgtc cgagtttagt gtccaagaaa aagagcatga gagcaataac aatactcaca
     9061 aagatgagac ctgtcaagag ttgattcaaa tccgaatcaa aaggcaaaac atcctgaatt
     9121 tgcttggttc caagcaggcc taaattcgca cgtcccataa tcaagagcat gattgagtga
     9181 caagaagtca tcaccaaaat ccctgagagc aaggttggga tcttcccttt tgtataaaga
     9241 aggcctgctg ccattccagc caaacaacct gctcctacag caacaagtgt cgctaaaaat
     9301 gggttcacgc ctttggttat caaagtgaca gcaacagctc ccccaagagg gaaggaacct
     9361 tctgtcgtca tatctggaaa gtttaaaatc ctaaatgtca taaagattcc cagacctaga
     9421 atagcccaga caaatccttg agaaataatg gaaacaatca tattttattt aatcctttct
     9481 atattcatct ttttaaaaaa tgggaagagt ctcctcctcc ctaccttatt tattcgatga
     9541 cttgtcctgc ttctttgaga acagactcag gaatagtaat acctagttct tgtgctattt
     9601 ttttattgat gactgactta ccagttgaaa agacattgac tggggtatcg gctggttttg
     9661 cacctttcaa gacttgcaca atcattttac ctgttgccac accaaggtca tgttggtcaa
     9721 ttacaactga tgccaaacca cctacttcta ccatagctgt cgcactggga taaattggtt
     9781 tcttagaact ttgattgcta gagacaaccg ttggaaatcc tgatgcaatg gtgttatcaa
     9841 ttggaaccca aatagcatct accttgctag tcataacagt gacagttgag gcaatttcat
     9901 ttgttgaagg aactgcaaat gtttccactg tcagacctgc tttttcagca taagccttaa
     9961 attcttcgac ctgtgttttt gaattgtctt cgctacttga gtaaagagct ccgattgttt
    10021 tcacattcgg tgtcagagcc ttgatgagtt caacttgttg ttgagctgga ttgtggtcag
    10081 atacccctgt aacgttgcca cctggttttt tcaaatcttt aaccaagtta gcaccaattg
    10141 ggtctgtaat agcggccatg ataaccggta ggtcttttgt tgcactagcc aacccttggg
    10201 ctgctggtgt tgcgatacca accacaaggt cattcccatt tgcaaccaat tgtttactca
    10261 ttgtcgcaac cttactttgg tcaccttctg agttcataaa atcaatttta acttgatcat
    10321 ctttatatcc ttcttctgca agtccatctt ggatcccttt ataaatcaaa tcaagggatg
    10381 gatggctcac aaattgaagc acaccaatct tggttatttt cttctcatcc ttattattct
    10441 gagcttctga tttattcatt gaagaataaa tcaagcttcc tgctactaag actgctaatg
    10501 cagcaataat tccaattaaa cgtttatttt tcattctgtt tctccttttt atttccttta
    10561 acatatttca cttatctaaa caagcgacgc cattgttttc tttccatact aacctccatc
    10621 aaaaaaatcc tcacacaaaa aacttgtgtg aggacgtcga tgcgcggtac cacctcaatt
    10681 atagggaatt tccctatcgc tcagtctcgc aataacgaga tgcactgtaa ggtgtgctta
    10741 ccgaattttt ataatttcaa attctaaata gcattcagcc caattttcat cattgccact
    10801 tatctgtttt cagctaccac agactctcta aaaagtttgt atgattactt ttctgaatgg
    10861 ttaaattata tcatttttaa actacttgtc aatagtctat tagaattttt ttgatattca
    10921 cttttagcat tcactcttga aaattatcaa cctgaattac gcaatcctgt cgcaattccg
    10981 ttgatggtga tatgaatcaa tcgttcttga tcactggaca attctccacg acgttggcgt
    11041 ttaatcaact ctaactgaat atagttgaga atattaaagt aaggcatacg gtaatccaga
    11101 ctagctttta gatatggatt gtcagctaag agttcgtcat gtccttcaat agccaagata
    11161 acgttcttag taacttgcca ttcatttaaa atagtctcat agatggcctt aacttgctcg
    11221 tcttcacaaa gtttagcata ttcaaaagca atattcatat ttgattttga caaaaccata
    11281 tcaacatttg aaagaagcga ttggaagaaa ggccaatttt ggtacatatc tcgtaagata
    11341 gcaatattct ctggattttt attgataaat tccttgaagc ttgaaccaac cccgtaccat
    11401 ccagggaaca taacacgact ctgtgaccat gagaataccc aagggatggc acgcaaacca
    11461 ccgatttcag taatagtctt acgagcggct ggacgagaac caatattaaa acttgaaata
    11521 gccttgattg gacttgactc gaagaaataa tcatagaaat gctcattacc aaagaccaaa
    11581 tcacggtaga tatcgtaact acggtccact acttgatcca taatggcttc ataacgattt
    11641 ggggtattgg tatcgctctt cttctgagta atcatacggt taatagctgc cgatactagc
    11701 atttcaaggt tatagtaagc ggcgtctttg ttaccgtatt tattcccaat tacttcaccc
    11761 tgctccgtca agcggatacg atccttgata gacttgagcg gttgagatgt aatggcttca
    11821 taggttggcc caccaccacg accgacagta ccaccacgac catggaagaa ggtaacctta
    11881 acgccaaatt catctccaat agtagtcaat tgttgttgag ccttgtagag ggtccaacat
    11941 gatgacaagt aaccgccatc tttattactg tcagagtagc caagcatgat ttcttggtag
    12001 ttatttcgtg agtcaatcca ttttttggca aggctaagag aaagatattt tctcattgtt
    12061 tcctctgaat gatccaagtc ttcaattgtt tcaaaaaggg gaacaatctg aacacgcgcc
    12121 ctttccgtat ccaccagtcc tacttctttt aacagaatag ctaattctag catatcagaa
    12181 aggctggttg catgtgaaat gatggtctga cggatgacat catctcccaa cttatctttc
    12241 aaaacacgag ccgtcttaaa aatagctaat tcttttgcta ataattctga tttttctgcg
    12301 tgagtcgcag aaagaattcg gggatcttct tctaattctt tcaagagaag gtcacacttt
    12361 tcttcttcgc tcaactcgct ataacgagaa tgaattcctg ctgatttcaa gagttctgcc
    12421 acacaggctt catagacgct agagtcttgt cgcatatcaa ttgatgctaa gtaaaaacca
    12481 aatatctcta ctgcctgcaa taattccaca aaatcacctg aaatcaagga ctcgccctta
    12541 ttttctagta gagaatctcg aatggcaatc aaatccttgt agaaatcatt ggcggtttca
    12601 taacgagtcc caacttcttc atcctcaatc agataggttt tagttgcctg aatttttgat
    12661 tgaatatcaa acaaggcacg acggtaaagc tctttttcgc ggtaaatcga gttatccttg
    12721 gattgacgag ccatttctct gacttgcttg ctgacgttga caatgctagt tgaaagagaa
    12781 aattcacgat aaagttggta aatcttttta tcatagtagt tcatgatgac ttcacactga
    12841 gtgagtgcag actgcttcaa ggtctttgct gtaacaaatg gatttccatc acggtcacca
    12901 cctatccaca tacccatggt gattggttta gcctgtttta aattcagacc atgcgcttgc
    12961 gctaagcgct tatactccgt cgtcaaatga ggtacagctt tcaaaaagga gctgttataa
    13021 tattccatag cattcgtgat ttcgttagtc acttttaatt ttttctcacg aatcatgtct
    13081 gtctgcatga taatttcgat gtaacgacgc aaatcattgt accatttatc tttattgatc
    13141 aaccccaact taacatcacg gtatttacgc aaaagactat gaatatgatt tgttaaatcc
    13201 aacatacttt tgcgttgcac ttgtgttgga tgggctgtca aaacagggac aacattcaag
    13261 tgttctagga tctcaacggc attttccttt tctgctacca atttaatcgt tgtagataat
    13321 ttacctaaat agtcctgatc aatattattt tgatgattga tttcataagc taaatccaca
    13381 tcctctgaaa tattaatcaa aagaggcaag atagagaaat agcgtgaaat atagaccatt
    13441 tcatcatttg ataagctagt cactagacgg tttagacctt gataatcttc ctgcgttgat
    13501 aattctttca actgtattat tttttcaaag gtctctgggg caagcatatt tttagtaata
    13561 tcttccagta attctgttag aatcaagact tcttcttgca caacactttt attactataa
    13621 ttttctaatt tttgaagaga cataaactat cctttcttta tcctacttca acagaaggtt
    13681 cattggttga ttttccaatt ctcggtacaa tttagcgcgt ttttcactgg catcaatatt
    13741 taagacaaag gctactgcca ctgataagac tagaagacta tttccaccct gggataagaa
    13801 ggggaaagtc actcctgtag atggaatcaa gcccgaaatc cctccgatat tgacaaatac
    13861 ctgaaccaac atcatccctc cgacaccgag tgcaaccatg gcattgaaag gattctccgc
    13921 tcggataccg accaagataa tccgcaaaat catgaaaaac aagagagcta aaataagact
    13981 ggcaccaaca aagccaaatt cttcaatcac gatagaaaag acaaagtctg tatgagcttc
    14041 tggcaaataa cctcgttttt caatcgagtt tccaagacct agaccaaacc aaccgccatt
    14101 gaccatggca aaataagaat tagctaactg gtgacctgca tcagcacgat cggcaaaagg
    14161 attaaaaaag gcactaaagc gcttggctac atagccgaat actggaattt ttgaaaaggt
    14221 ctcaacaccg attaggctga tagtggtcaa gacaaagaca gaagcggcag atacgagcgc
    14281 cagaatggtt gaaaaccagc gataagcgat tccactaact gtatacataa tcaaggaaac
    14341 caagactaaa atagtcgcat ttcctaaatc agggaaaatt cccaaacttc caatcagaac
    14401 taggagaacg aatcgccaat cattaaaagc acggggaagc cattgatttt gagtcaaaac
    14461 ttgaaaatca taagtagcta tttcttcttg ctgtttggag aatcggtgag ctaaatacca
    14521 aataataatg atttttaagt actcagctgg ctgaatagtt actcctgcaa ccgaaatcca
    14581 accgtatgcc ccgtttacgg aaagaccaat aaaacgagcc aagaacaata gaagcatttc
    14641 tattaatata actaaaatga ttagtcgctc atttctcaaa aaatctagtc tcaatttata
    14701 aattaaggca atcagtatca aactaacaat ccaaaagatt ccttggtttc gaaccaactg
    14761 caaggcactc ttgccttctt caattaaaat agcactggtg gtcgaataga ccacaatcaa
    14821 gcccaaaata gataaaagca agtagggaat caagatggaa taatttaata agtgcctctt
    14881 actaatcttc atagcatcac cactctacta ggatacagac aaatctgttc caaattccgt
    14941 tttattttct agttttgatt gctattatac cattttttca gaaagaaaaa aactcttacc
    15001 ttataatcct tcgaatttta ctgtttttca taattagagc agaatttgaa atcgtaaaac
    15061 cattttgaac aagagttact tcaacccatt gactccgatg gattaagttg ctttcgtgaa
    15121 tgccaaaatc agccgaaatt tgttcataag tgcgctattc tcgcatgtat tgaatagtta
    15181 ccataaggag atcgtctagg cttaatttgg tttttcgtcc accttttgcg cgtttacgtt
    15241 gataagctgt ttttaacaca gctaacatct cttcaaaagt cgtgcgctga acacctacaa
    15301 ggatcttgaa acggctatcg ctcaattgtt tacttgcttc atcatccata gttttattgt
    15361 attgtatttt tgtttcgcag gaagtctatt attcctttcg ttccaaggtt tttacgcttt
    15421 tagcaacaag cttacacact gagcgtttcg gacttaccat atcatttcgt tggagatttt
    15481 atcatcaatt tttagattaa aaaagatttc ccaatcttca caaacttctg tagcaggaat
    15541 tgtatgaatc tttctaagta tctttcctgc ttctacacca tatgtgtatt gttggttttc
    15601 tgaataagct aaaatgctat ctattgcatc tcttccgtct atccattcgt gtaaagaatg
    15661 tacttcgtca tcgcagagtt caatgctaat tggtttacac atcggaactc caagagaagc
    15721 tactttctcc atcatatcaa attcaaattt ttttataatc taacttcgac ttatcagaaa
    15781 cacgcaagaa atatttttac tgattttgat ctgtcacaca atatttttta tcatctgacc
    15841 agcctttatt tatggctatc ttactactaa aatccatcaa gcacactccg attcacttta
    15901 caacactttt tgcagttttc actagtaacc tatccagttc gtctacactt ttatttccta
    15961 gatccatttt tacattatga aagttagtca attttctcta tgatgtttcc aagtttatcc
    16021 aatacaagac aagaatgatc atttagtgga attatgggaa cattaacgag ttcttcagct
    16081 ctatccttat ttgctttatc attccaggaa tcataatgga cactaattaa aaactgacta
    16141 aagagtccta atccattttt tatctttatc tgatgatctg aattatcatt aggtgagaca
    16201 tagacttttt ctcctaatag tagggctcct gcagaaaatc ctataatttt tgcctcttta
    16261 ttaagcatat aatcgatata acttttgaac tcctgattaa cataagtagc aatatatttt
    16321 tccgtatttc caccaccgat gataattatg tcagcatcta gatagctatc aagatcaatc
    16381 tgctcagtgt ccaggagcaa gtaatcaatg tttagattag gaaattgact ttgaaaaact
    16441 tccgtgtact ttttcatgta cggttcccaa ttttctcgaa aaactgtaaa aatgataatt
    16501 cttttaatct tggttgataa tacaatttta tcaacaatac tatatttctt cattggggga
    16561 ttcccaccca tcaaaaaaat ttgttctttc aagttaacac actttctaaa gatacataaa
    16621 gtttaaacaa gtttattcac gtttcgaaat tataattttt ttaaaacata tcattttatt
    16681 gactggctaa gatcgaacca gcaacactac acactccacg tgtgttgtct gttccttgag
    16741 aatacaattt tttatcctcg tcactgtttt gaggacacaa tttatctgtt tctagtttag
    16801 catttttacg tttactttta aattgtttac catccttgtt ttgaatttca cctgttttga
    16861 atattatggt taacattgca ggatcaattt ctccgttgct attaactcca cctacaataa
    16921 ttttctcaac aatactttca aaaactgcac gatcaaactc cgtaagcatt ttttgcgaag
    16981 atagcaagtg cttaaactca gttagtcttt tctttacatc gatttctgat tttaatgttg
    17041 tttcaatatt taccttctct tctgctagaa actctttttc tgaggaaatt tcattgtact
    17101 tttcattgta tatggaatcg ctaacttttc cttcgagcct tagatttaca agattctcct
    17161 ctttttttag taatattcga agtttgtttg taatcctttt tagttccttg ttaaggctat
    17221 tgtcattcaa ttcagattct atcgtttcaa gtaagtctgt cattaaattt tcatttgaat
    17281 gatagacttg tctgtaagct tccaggaaag ccccctcaat ggcgatctct tctaatcctt
    17341 tactatgctt acaaaatttc tttcctttct ttatcgatgt aacacagtgc cacacaactt
    17401 tgcgataatc tgaacggcag tgccaacttc ttctagataa tattgaacca caaaaaccac
    17461 attccaacat gctactaaaa gcatacattt ttgaatagcg ttcacgcttc ccatttacat
    17521 tcgcagctgt cttcttattt cctgctcgac gcaatctaat ctcctgagct ttttcaaaat
    17581 cttctttaga tattattggt tcatgattat ccttgatata gtacttatct tcttctccaa
    17641 aattactcaa ccgtctcttg cttattgggt caactgtaaa agtttttccc attagaatat
    17701 cacctttata tttttcattc tttattattc ctagaactgt tgtatcattc cagtgttcta
    17761 aacctcttgg cgatttgtaa ccaagttcat caagttccct tgcaattact tttcctccaa
    17821 taccttctag atacctttca aaaatataac gaacaatttt ggcttctttt ttattaattg
    17881 aaatctgctt ggtttctaca tcataatcat accctaagca cccttgaaaa ccaaccaatt
    17941 caccacgttg catcttcatt tttaatcctt ttttcacatg ggcagaagta ttctctactt
    18001 cttgctgtgc aacggagctt agaatagtta gaagcaattc tccatccatt gttagggtat
    18061 ctatgttttc ttcctcaaaa tatactccaa tttgcatatc ctttaacatt ctgacatact
    18121 tcaaagtatc tagggtattc cttgcaaatc tagcaattgc ttttgtgaca atataatcta
    18181 tctctccatt tgcacaatca ttgattaatc gttgaaaatc ttgtctcttt cctacttgtg
    18241 ttcctgaaat accttcatct gcataaatat ctgccagctc ccaatctgaa cgctgagaaa
    18301 tatattcttt gtagtgtctt acttgagaat cataactgtt tttctgatcc tcactatcga
    18361 aactaactct gcaataagca gcaaccctct ttaagtgtct ttctacattg tcgcctcttc
    18421 gacgaactaa agaatcagct tttattattt caacattatt ttttttcata ctgaaattcc
    18481 tccttttgat tctatattac cgcattcaaa tcaaaaagtc agctattttg tgtacttaat
    18541 acgcagtttg tttctaatct tgtcatactc atttttagat aacatatttc ttgagtataa
    18601 aaagttaagc attgatagtt gcatagtata ctttattact gattgttcca aactttttcc
    18661 tccttgtaac atgtataatt tcctccgtgg gtatgactgg ttaaatcatt catgggcatt
    18721 tcacccgctg tcctttttcg ctggcagcct gaacgttcag aagtatcatt atccttattt
    18781 gtagtcatgg cagatagaga accactctat tttatagcta ataattatcg ctcctatcac
    18841 ggcgtatcaa gctaaagtgc tcgacaaata agaaagtccc acctcggttt attcagtttt
    18901 caaagggctt aggatttatt aacaactaaa cttatccatc tctaaaatat aatctgtagt
    18961 tacctgatat aatttagcta attgtttcaa aaatgatgta ggaatatctt gcttgccact
    19021 ttctattcta gaataagcag actgtgaaca atgaagatac tgtgcaattt gacactggga
    19081 caaatctttg tcttctctta aattctttaa tctgatatac attaataatc ctcttactaa
    19141 tattgtaatt tgaagattat caaatttgga attttatgca aaatatgcat aaaataattt
    19201 ataagatttt agaaatagtt ggtataacag taagtaagct ataagttact aaaaaaagat
    19261 tttggaataa actttttcat agcgataaaa gcaccgtaca agctaggaaa ataataagta
    19321 atcgcccaat ctgaccttct ccagaacttg attattcgtc aatcactaca gttgacaaac
    19381 atactaagat tagtagtgag gaaatctcca acgggagaga gtactcatta ctttttcttt
    19441 gtgttaaaat agtggtgtct tgttaagtca tagagctctc tatggtgcta gacgtcgctt
    19501 gacaaactgg caagaaacct gttttaggaa gaattttatc aaagtatgtg ggatactaga
    19561 cgtcgagtat tggaaataaa atcactaaaa caaggagtca ttcaagacaa aggggtaaac
    19621 atggtgcgga cagttttcag aatggatgtg agtaaggcaa gctcagaagt cgctattctt
    19681 gtgaatggtg aaaaggttca tggctatacc atgcccaatg atgccatcgg atttagtcgt
    19741 cttctagagg atttgaaata ggtaaataca cctgagatta tcttcgaggc acaggggtct
    19801 attctcgtct tcaggccttt ctggaggaca atagctatgc ttatatacgg ctaaatcctt
    19861 taaaactaag aagcaactag acagtttgcg agtccgtaaa accaatcaga ttgacgctga
    19921 aaagctagct tcgtcacaat tcatccttaa ccgcaaacca acttatgttc aagaagaagt
    19981 ctatcaaaat ttgcgtgacc tcagtcgatt ctatcagaat ctgacagaag acatcgttag
    20041 gactaagaat agcctgcaca aggtgcttca aattgccttt ccagaaataa agaaccttct
    20101 ctctactcct acaggggaac aatattggaa cctcgtgacc atctttccaa ccaagcattg
    20161 gaggctgaaa ttatcagtag ttgagctaaa agaagccatc gtaattcaac ttctaaacgg
    20221 atttctgaga acagagttgg acgattggct gaaaagttga gcgagctggc cgaacagtcc
    20281 tatcttgcca tttcaaaaac ctctcccatg acagaagagg ttaagtatca tgcacaggaa
    20341 ctgttgagac tgacaaaccg caaggatcag gacttagcac aaatgattga attggctgaa
    20401 ccattacctg aatacgagat tctgctctct attcctggta tcgcagaaac aacagctaca
    20461 agcattattg gcgaattgga gacattcgtc gctttcagtc tgccaaccaa atcaatgcct
    20521 ttatcagtat tgacctcaga cactatgaat ctggcaattt cctagctcaa gaacatatca
    20581 ccaagcgtgg aaatccttac gcgagaaaaa ttctctataa gtgcgtccac aatattgctt
    20641 cagctagtca taccaatcct tgtcatatcg cggactttta tgagaaacga aaaagacaat
    20701 cgcagacgac ttcaaccaag ccatatacga ttgtctctat acatcgcctc atccggacaa
    20761 tgtattacct cataacgcat aacaaacttt acgactacac tttaacccaa agtcattaaa
    20821 gtcatctatg tcctatcatt gtaacacctt attttttaat accagataag tgtcttttaa
    20881 gtgtgcccaa atttcaaaaa acagctcgca attatcttct aaacattcct ttgatactca
    20941 ttcagaaaac cttttgagct agaatatcgt atgtccctta acaaatggta tgtataaaag
    21001 agctaaaaaa ccactcatgg tatgaacgag tggttatgac tgaaatatta catacctttg
    21061 tatcattttt gcacaatggt caaatttctt gtttgaaaaa ctacagtaag cctaatcaaa
    21121 gctctcaatg tatcattaaa acttccttcc aaagaatagg aagttctatc aaaattctta
    21181 attagatttt acttcttcta agaccctgcg ctctcatatg catccaaacc tttgttccat
    21241 aattttaatg ataaggtaaa aaatattaat gagataagga tcaatccacc aatattgaac
    21301 aatccatcct tgtctttcaa gaaatagcta gctgggtaat aggctgtaaa agcaaaagga
    21361 atgataaaac taatcaacca acgtaaaaac gaatggtaaa tcgcaatcgg gtattttgca
    21421 aaatcattaa acatgtaaaa aatataaatt attgccccag attgtttagt ccaaaaagca
    21481 atactagctg ttacaatttt taaagaggta taaattaagg ttgcaaaggg aatactgatt
    21541 aaaaagagaa aaacctttgc ccaagtccaa gtaagactag ttattgtcat taacagcaat
    21601 aagacgccta ctaacaattc tccaagagca tcaatttgaa acgtttctac taaaatatga
    21661 aacaaagggc taatgggtct agtcaaatac ttatcaaatt ctcctttacg aattaaatgt
    21721 tgtcctaaag cccacagatt atcaaaaaag agatggtcaa ttcccttagg aatgagagaa
    21781 aaaccataaa taaaagcaac ctgatgaaaa ctccagccat caagtaaggg aatatgttga
    21841 aacaaaatat ttagaaacag catgtttaac ccttgtgtca aaaagacacc cacaacacca
    21901 actaaaaaat cagccttata ctccataatc tgtttaagat attgtcggat aaaaatcagg
    21961 tgcatgcgtt gatatttctt cattctaacc tccttgaata gttatataat tctgtacgca
    22021 cttccaaatc agttgggata aggcaatcat aataaacagc cagaataatt gtagcgagag
    22081 cgcctgaatc atttgactca tgctatactt ttctataata accatcaccg gggtatagat
    22141 taaagaagaa aatggcaaaa aagataatag ttcggcaata atttttggaa aaaatgtcag
    22201 aggaaccaaa cttccagata aaaaggcaac taaagaattt ttcaaaagat ttgatcccca
    22261 taagttttta aacacaaaag ctgaaaaacc aaagcaaata ttgaaaaaaa aattaatcaa
    22321 aaaagctaag attaagctaa gaaggtaaac tgtggttatt aaaacaattt gtaagaagga
    22381 ctcacctgat aagagcttta gacctgcaat cagaattaca aatggtagac caacactaac
    22441 aaaaactagc catctagacc caatttctgt gaaaagataa gacattgcaa aatgaactgg
    22501 acgaagcagt cgcataataa tagagccatc ctttacttcc catccaatca taaaagaact
    22561 atctgatttt gtcagtagat tcgtcacaaa actcatgatg atatataagg tcatatcaga
    22621 taaagtaaaa ccttgaatga gagactggtg agatgaatca aacacagctt tccacaagta
    22681 aaatgctaca aaggccccca tcacatcccc aatgcgataa agaaaaaaat tgacacgata
    22741 cgtgattaat tcttggattc cagcgctaac aaaaggctta tagcgtttcc ataatttagt
    22801 catcctaaag ctcctttcga tagaagcgac gaataatatc ttcaatattc gcatccgtca
    22861 tctttaaatc acggatcgta aaatcagaca aagtttgttg aataatgtca gccgtttgat
    22921 actgcgagct gtcgtactga atatcaagtg acaattcctg tctcgtcaca tagatatcag
    22981 aaagtccttc aaaatgagag acaatataat cctgcccagg atgtagttca aaagagagag
    23041 tcttcatctt cccgaaagtc tttttcagtt gattcacagt tccatcaaag atttctcggc
    23101 ccttatcaat cataaaaata cgatcacata actgttcaat atcacctaaa tcgtgggtcg
    23161 ttaaaagtat ggtcgtctct tcttcttgat taatctgtgt aatggcacgt cgaatattat
    23221 ccttgaccga aacatctaaa ccaatagtag gctcatctag gaaaagaact ttcggattat
    23281 gcaataagga ggccgcaata tccgccctca tacgttgacc tagagataga gttctgacag
    23341 gatcttgaat aaattccttc aaatctaaaa cttcatttag aaaatccatg cgtttttgaa
    23401 agaccgcatc aggaacatca taaatttcct ttaaaaccga gtaagtctcc tgcaaagcca
    23461 aatcccacca aagttgagtt cgctgcccaa aaactacacc aatatcttta acatagcctt
    23521 gacggttctc ttgaggaatc tttccattga tacgacaaaa acctgatgtt ggtttcaaaa
    23581 tccccgtcaa catcttgata gttgttgatt tccccgctcc atttgcgcca ataaagccta
    23641 aaatttgtcc tttgggcacc tcaaatgata aatctttaac agcttcaaag acttgtctct
    23701 tgggatgaaa aaaagagcga aaagctccct ttaagccagg ttcctttatt gttttcacaa
    23761 aatttttctg aagatgctct actgttatca tttttataaa tcactccttt cgtttcactc
    23821 aagttataat atcaacaaaa attgtagcat actacagtaa agttaagaaa atttaccatc
    23881 attacaaacc atatgaaaaa agctactaaa actatgccat cttgtatttt atctgtaagt
    23941 aagctaaatt actcaagtac aaagaattat gacgaagaac atataaattt ataattggat
    24001 aaactataga tttcagcaaa cgaagttatc ccaatataaa aatactttaa taactgaaga
    24061 tattgacagg aagatattaa attcctcatt actatccttt actatgcagt ataattttaa
    24121 tatcatttac ctacttccaa gatgctgaaa aatactaagt cacactatta tgatgttatt
    24181 atttccattt ttattttaac agatgagtca attctttcaa ctaccccctc ccttataact
    24241 atattcatga agtattcttg ataataaacc tcatttaact tctcaaagta gtcagcttct
    24301 gcaactgcta ttatctcata acagattgat ttggtttcaa taaatggaag ctagaagcct
    24361 tgtcagctac cctgcacagt tggtgttttt tcatttttct cttcaaaaaa attggtcgga
    24421 agttataata aaaaggtgat gtgtttgtgg tgagttgaat taagagacaa actcactttg
    24481 tcttaacttt taaattgcct aacaaaaata cggagattat tctctaagct ttaactgcaa
    24541 cattatgtct ctacaaccaa cgataagtcc agaaatctac ccaaataacc aaacaaccta
    24601 catttgttga actttgatga caagtaggaa attttacatt tgataaacac tattttgtac
    24661 gcattttgca cataatttaa cgtgctttcc atcaatttag ttaaggactt acatagaaaa
    24721 caatccgttt ttgcttatgt taaattagta gaattagaca aaaacaaaac cgccgttcgc
    24781 actgttatat attcattttt agtacttact attctaaaaa agatatctat ctttcaattc
    24841 ctcaatttct tgactactta ttcctagttc tgtattaata tatctaagta ttcctccata
    24901 ttctttatca aggacattca atactcgatt aatatattct tattttgctg aactgagtga
    24961 aagtaaatta tgcatcaata ttacattccc actatggtta tttacatatt caatattttc
    25021 ttttctcaca tttattaaat acttgttaga tagtaagtaa tcatgaaaaa tatcgttcat
    25081 atctactccc aatatataaa gcaagaacaa gctagctatt cctgttcgat ccttccccat
    25141 tgaacaatga aacaaaagag attcatcttt tggatgactt agtaataatt taaagaattt
    25201 cttgtaacca agtttactct gtttttgatt gatcatttga tcataagttt ttatcatatg
    25261 ttgaaaacct gcatctgatt tgttaaaaaa ttctattggg aattctgtca actctgaatc
    25321 atcattatag aatattggaa ttactatatt ttttatattt tttatatctg gatctggagc
    25381 tttttttatt tcattcgctg atcgaaagtc aatgactttt gttattccat agctctgtaa
    25441 caaatcgaca tcaattttag agattccaaa tagtttactt gaacggaata atgttttagg
    25501 ttttattttt tgtcctgttt gagtgaggtg gtttccaaga tctctaaaat tatattcttt
    25561 tagtaaagtt agattattca atgcttttct ccataatatg ctcaaaaaac catctttatt
    25621 ttattcaaca tctccggttg ttaatttaaa ttaaaaaagg ctactttcga gtatttttga
    25681 attatctact ggatgtttgt tgcaattcta aaacttcctc gtcaattttt ttcaaatcaa
    25741 tcctatcaaa caacattgat acatctgata gcttgttagg aaggtttgaa atataattcc
    25801 aagtatttag ctttgtttta aacatatcct caatcttttt accagaaaaa ggaatgaatg
    25861 gatttaacat ttgtcctaaa ttaagtataa tgattacaca agtagctaag acttctttac
    25921 atttttcaat atcggactct cgcaatgccc acggtttcat atcatcatag aatttattag
    25981 ccgatctaat atattcaaaa atttcttcta atgcctgttt catatgcccg ctctcaacta
    26041 aattacctac tgttgtatat aattctttca aattatataa aatttctcct tcgagatatt
    26101 tagtgggtat ttcagattca aaatactttt caataaactt tagagtccta ttgataaaat
    26161 taccgtacga tcctaataat tctgagttat gactataaat aaattctctc caagaaaaat
    26221 ttgcatcttt catctcagga gcatttattg ttaggaagta tcggattgaa tcagcatcat
    26281 atttttttat gatatcgtta agccatatag cccaattatt acttgttgat atttttttgt
    26341 tttctaacgt taaatattca ctagaaataa tatactctgg aagaggctct atttctaaac
    26401 ctgagagtat tgccggccaa ataatagtat gaaatgggat gttatctttt ccatgaacat
    26461 aatatgactt tgtccgattg ttccaaaaat cagtaatatt attttgaagt ttttgcgccc
    26521 aatcaacact tgctgtgtag taacctgcta ccgcttcaaa ccagacatat atttttttat
    26581 ctctaaaacc atcaatggga actggaatcc catttggtag atcacgagta acagctcgat
    26641 caggtaaacc ttcccgtaaa taccttttag ttagatttat tgcatttttt cgccatctca
    26701 ctgtttcttc agcatcattt aagtaagtct ctaacaaatt ttgaaactca ctaaaaacat
    26761 aataaaagtg ttctgtctca cgaacttctg gttcattaga acaaatagaa catcttttat
    26821 caactaaatc tataggatct aaaattgctg agcaattatc acattgatct cctcttgaat
    26881 gggttccaca attcgggcat tttccttcaa cgaacctatc aggtaagaat tgattatcaa
    26941 atgtacaata gagttgttta attttttttg tatacaaaaa tttcttctcg tataattgca
    27001 aaaataattc ttgtactatc tcatgatgta gtggagaatc tgttcgcgag tacaagtcat
    27061 atgtaaaacc taatttttca aaagtttctt taaattcctt atgataaaaa tcagcaattt
    27121 ctttcacaga cttattttct tttttagctc tgatagaaat aggggttcca ttacaatcac
    27181 ttccagaaac atataaaact tcctctccct tctgacgata gtatcttgca agaatatccc
    27241 ccggtaaaag cgctgccgcg tgaccaatat gtaacgaacc gtttgcatat ggccatgctc
    27301 ctccaataaa aattgacata ttgtatttct ccttaaattc tttattttta ttataacatt
    27361 atttaaatgc aatatctttt caatcattac tttttttgaa aatattcatt tattttattt
    27421 acaaaccttt gcaataacac aaaaaaatta gatacgtgta atccatctcc cattccatga
    27481 ttaatttgta aattcactgt acaaaaatat ctttggttct cttgaataac ttttccccac
    27541 gttattcgag gaactgtatc aatttttgaa agattcatag gagtgcttac atgtaaaaaa
    27601 tcaatccatg gaacacaaga aagataagca atgttattct tgtcaatatt tggtttttgc
    27661 ccttcttctg ccttctgttt atttatgttg aacgcagaaa caaattcaat taaattatct
    27721 cccatcgtaa atgaagaaaa attaagctta tcttccgatg taagggtagt gaaagaacaa
    27781 cctctttgat tgtattgcca gacaatcttt ccgtcggtat ccattagtaa ttctggaata
    27841 gaatttattg cactcataac acaccacgat attatggcat aaagtgatat cgaatgtttt
    27901 ttatgaaaat tgatagcctg cgttacttct attcgtgaac tcatagataa ataaggaaca
    27961 tccattttat tgaaaaagtc aaattcttca ttccttttcc actctgataa atgaaaaatt
    28021 ccatcccaac tcctccttat aataaaaata gggtgtagca ttcttttttc atgctacacc
    28081 cacaatcaac catctttaag gcttactctg acaagtaagt taataagaat ctggactcca
    28141 agaacctgaa gtatgaattc ttacatgatt tccaaattgt ggcgccatag ctaatctagt
    28201 accagaacca atataattgt caccacctcc attatagtac atgacaatcc tagatccaga
    28261 ccccaatgaa tataccgggg taatatctga cccactatag gcgctacgaa tagaggtatt
    28321 taacctttta ccgccaccag tgctgtca
//
LOCUS       DBEROT010000030        27074 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.30, whole genome shotgun sequence.
ACCESSION   DBEROT010000030 DBEROT010000000
VERSION     DBEROT010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.30"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(59..853)
                     /gene="pflA"
                     /locus_tag="ACL8CG_001457"
     CDS             complement(59..853)
                     /gene="pflA"
                     /locus_tag="ACL8CG_001457"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGS1344034.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(979..2229)
                     /locus_tag="ACL8CG_001458"
     CDS             complement(979..2229)
                     /locus_tag="ACL8CG_001458"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGS1344035.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTPAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(2296..3123)
                     /gene="purR"
                     /locus_tag="ACL8CG_001459"
     CDS             complement(2296..3123)
                     /gene="purR"
                     /locus_tag="ACL8CG_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGS1344036.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(3390..4331)
                     /locus_tag="ACL8CG_001460"
     CDS             complement(3390..4331)
                     /locus_tag="ACL8CG_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGS1344037.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(4321..5577)
                     /gene="rmuC"
                     /locus_tag="ACL8CG_001461"
     CDS             complement(4321..5577)
                     /gene="rmuC"
                     /locus_tag="ACL8CG_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGS1344038.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(5579..6241)
                     /locus_tag="ACL8CG_001462"
     CDS             complement(5579..6241)
                     /locus_tag="ACL8CG_001462"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGS1344039.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(6204..6860)
                     /gene="rpe"
                     /locus_tag="ACL8CG_001463"
     CDS             complement(6204..6860)
                     /gene="rpe"
                     /locus_tag="ACL8CG_001463"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGS1344040.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(6871..7749)
                     /gene="rsgA"
                     /locus_tag="ACL8CG_001464"
     CDS             complement(6871..7749)
                     /gene="rsgA"
                     /locus_tag="ACL8CG_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGS1344041.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(7751..8623)
                     /gene="rsmA"
                     /locus_tag="ACL8CG_001465"
     CDS             complement(7751..8623)
                     /gene="rsmA"
                     /locus_tag="ACL8CG_001465"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGS1344042.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(8754..9062)
                     /locus_tag="ACL8CG_001466"
     CDS             complement(8754..9062)
                     /locus_tag="ACL8CG_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344043.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(9055..9696)
                     /locus_tag="ACL8CG_001467"
     CDS             complement(9055..9696)
                     /locus_tag="ACL8CG_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344044.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(9698..11728)
                     /locus_tag="ACL8CG_001468"
     CDS             complement(9698..11728)
                     /locus_tag="ACL8CG_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS1344045.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFIDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(11805..12101)
                     /locus_tag="ACL8CG_001469"
     CDS             complement(11805..12101)
                     /locus_tag="ACL8CG_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS1344046.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(12421..13320)
                     /locus_tag="ACL8CG_001470"
     CDS             complement(12421..13320)
                     /locus_tag="ACL8CG_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1344047.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(13392..13952)
                     /gene="rnmV"
                     /locus_tag="ACL8CG_001471"
     CDS             complement(13392..13952)
                     /gene="rnmV"
                     /locus_tag="ACL8CG_001471"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGS1344048.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(13952..14725)
                     /locus_tag="ACL8CG_001472"
     CDS             complement(13952..14725)
                     /locus_tag="ACL8CG_001472"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGS1344049.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(15031..15783)
                     /locus_tag="ACL8CG_001473"
     CDS             complement(15031..15783)
                     /locus_tag="ACL8CG_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HGS1344050.1"
                     /translation="MCPVIILFYYKVEVAGDGTATITFPDGSVVTILGKDTVQQSAKG
                     ESVTQEATPEYKLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASK
                     QLATEKESAKNAIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTM
                     EDVKEAETIGVQAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPN
                     TGSASSAALASLGLVVATSGFALLGRKTRRRK"
     gene            complement(15959..16093)
                     /gene="rpmH"
                     /locus_tag="ACL8CG_001474"
     CDS             complement(15959..16093)
                     /gene="rpmH"
                     /locus_tag="ACL8CG_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGS1344051.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(16238..17452)
                     /locus_tag="ACL8CG_001475"
     CDS             complement(16238..17452)
                     /locus_tag="ACL8CG_001475"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1344052.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(17608..17902)
                     /locus_tag="ACL8CG_001476"
                     /pseudo
     CDS             complement(17608..17902)
                     /locus_tag="ACL8CG_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            18064..18516
                     /locus_tag="ACL8CG_001477"
     CDS             18064..18516
                     /locus_tag="ACL8CG_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGS1344053.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(18551..19939)
                     /locus_tag="ACL8CG_001478"
     CDS             complement(18551..19939)
                     /locus_tag="ACL8CG_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1344054.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            20005..20967
                     /locus_tag="ACL8CG_001479"
     CDS             20005..20967
                     /locus_tag="ACL8CG_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGS1344055.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPYIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(20996..21289)
                     /locus_tag="ACL8CG_001480"
     CDS             complement(20996..21289)
                     /locus_tag="ACL8CG_001480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344056.1"
                     /translation="MNTIERTRRLIKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDETNEVSSKHVFEVVDETNEVSSKHVFEVVDRTDEVSNHTYGKAT"
     gene            complement(21353..22363)
                     /gene="ccpA"
                     /locus_tag="ACL8CG_001481"
     CDS             complement(21353..22363)
                     /gene="ccpA"
                     /locus_tag="ACL8CG_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGS1344057.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(22788..23387)
                     /locus_tag="ACL8CG_001482"
     CDS             complement(22788..23387)
                     /locus_tag="ACL8CG_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1344058.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(23388..24485)
                     /locus_tag="ACL8CG_001483"
     CDS             complement(23388..24485)
                     /locus_tag="ACL8CG_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGS1344059.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKSSLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRDDGCGFASISGDELHTVR
                     NRVFPFSGEVSVISQKHPTEVQVRLLYKERK"
     gene            complement(24485..25222)
                     /locus_tag="ACL8CG_001484"
     CDS             complement(24485..25222)
                     /locus_tag="ACL8CG_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344060.1"
                     /translation="MKRWLALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTGFSMMSTAIFSFPAVLHTDKMNNWQKILRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPVSLFPDWMQAIGKRLPSYQLMELIKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(25224..26108)
                     /locus_tag="ACL8CG_001485"
     CDS             complement(25224..26108)
                     /locus_tag="ACL8CG_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344061.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEVDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLVQAGCGIQEIEV
                     NNRSLLDTIFEETQKGDN"
     gene            complement(26095..26289)
                     /locus_tag="ACL8CG_001486"
     CDS             complement(26095..26289)
                     /locus_tag="ACL8CG_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344062.1"
                     /translation="MKKGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(26286..26492)
                     /locus_tag="ACL8CG_001487"
                     /pseudo
     CDS             complement(26286..26492)
                     /locus_tag="ACL8CG_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         7825 a         6282 c         4993 g         7974 t
ORIGIN      
        1 tttgctcttt gattttcatt gagtatcaaa agcccgatgt ttccatcagg cttcttttct
       61 atccatgtac acgtttcata taatcttgat aactttcggt atccatgagt tttttagcgt
      121 tcttgacgcg atctgctgtt ggtggtttga ctccttcgag ggaatatgga attccaagtt
      181 cacgccactt gaactcaccc atggtgtgat aaggtagaat ttcaaactta tcaacatttt
      241 tgagggtctt gacgaactta ccaagttcaa tcaagtcatc atctctgtct gtcaatcctg
      301 gaactagcac gtggcgaatc cagacaggtt ttccaatatc tgatagatac tgggcacaag
      361 ccaagatatt tttattagtt tggctagtga caatcttgtg ctgttcttcg ttgatttcct
      421 tgatatccaa aagaaccaag tcagtgacag ccatgagttt gtcaaacttc tcaaggtaac
      481 gtggtttatt acggaaagga agagcacagg tatccaaggt acagtggatt ccttgttcct
      541 tagccttggt gaagagagca atcaggaaat caatctgcaa gagagcttct cctccactga
      601 ctgtaatccc acccttattt ccccagaaac cacggtagcg caaggcctct gtcaagacat
      661 catctaccgt ccgttcacgt gacttattgg actccatagc ccaagtgtct gggttgtggc
      721 aatactggca acgcatgtga cagccctgca aaaagacaat aaagcgaata ccaggcccat
      781 ctactgaccc aaagctttct gtcgaatgca ccattcctgt cacttgtcca taatcaattg
      841 tttcttcaga catatcgtta ccttccttga aaacgtttta tagttttatt atatcacgac
      901 ttgaaggaaa aacaagattt ttgcctattt tttagaaagc aatctgtttt tcaatttcat
      961 tttcaatcta ttatcagatt attcttcaaa atcgaagcca tataaggttg caaaatagtc
     1021 ctcagggcgc tctgcacggc ggatttgacg ggctttacct tcttcggtat agaggatttc
     1081 cgcagaacgt aatttggcat tatactggta gcccattgaa aatccgtggg cacctgtatc
     1141 atgaattacc agcaaatcac cgatttctgt atgaggcagt tcgcgattga ctgcaaattt
     1201 atcattgttt tcacagagtg aaccaaccac atctaccgct tcagctggtc catctggatg
     1261 ggtcacgttg ctaatatgat ggtaagctcc gtacatagct ggacgcatga ggttgactgc
     1321 tgaggcatcc acacctagat aggtacggta ggtttccttc ttatgagtca ctcttgtgac
     1381 tagagcaccg tgaggtgcca gcataaaacg acccaattcg gtgaaaatct tgacctgacc
     1441 aagacctgct ggcgtaagga cctcttcata caccttacga actccctcac caatcaaggc
     1501 gatatcgttc ggctcctggt ctggacgata attaacacca ataccgccag aaagattgat
     1561 aaagtctagc caaatgccca acttttcctt gatttcaaca gccagttcaa agagctgacg
     1621 agccaactct ggataataga gatgggtcac ggtattggac gctaggaagg agtgaagccc
     1681 aaaagtcttg gctccttttt ccttcaagat agcaaaggct tcaaagagct ggtccttggt
     1741 catgccaaac ttagcctccc caggattatc cataatgtct gtccccagtt caaaaacgcc
     1801 tccaggatta taacgacaag agatgatttc tggaatgcct gctactctct ccagatgttc
     1861 aatatcttca aaggcatcca agttaatggt cgcacccaat tcacgtgcat aggcgtattc
     1921 cttgtctggc gtgttgttgg aagagaacat aatctcagaa cccagaaagt ccagtttatg
     1981 gctcatcaaa agctctacat aactagagca gtccacacca caaccttctt cttggagaat
     2041 tttcaaaata gctggagttg gagtagcctt aactgcaaaa tattccttaa agcccttgtt
     2101 ccacgaaaaa gcttggttga cggctcttgc cttctcacga atccccttct catcatacaa
     2161 gtgaaaggga gtcgggaact cggcaacaat cgcttctaac tcttctctat tgataaatgg
     2221 tgttttcata agcttccttc tattctgttt gcaaagaaag gctgggacaa tcgttccaac
     2281 ctttagttct atctcttatt tatcttcgtc aaagatattg ccaacctcaa catcgatggc
     2341 ttggttcttg acatcaatat tggttacctt caagagtgac ttgtagtcaa actgcttttc
     2401 acgttcttct tgggcattgt ccgcaaagac cgctacacct gccagttctg agtcgaactc
     2461 gcgcaagaga ctaatcatac cattgaccgt tccgccacct ttcaagaagt catccacaat
     2521 caagacacgg ctgcctgcct taagactacg ttttgaaagg aacattttct cgatacggtc
     2581 accacttgaa cctgaaacat agttgacgct aacagttgaa ccttcggtaa ttttcaggtc
     2641 acggcgcaca atgacaaaag agacattgag gacattggca actgcatttg caagtggcac
     2701 acccttagtt gctacggtca taaccgcgtc aattttttgg tccataaagc ttttggcaat
     2761 aatacgacca atatttttca agatggctgg tgtgctaagc aaatcagaca gatagatata
     2821 accacctggc aagatacggt cactttctga caacttggta cgcaagtctt caaccatttc
     2881 cttagcatcc tgactcgaaa tagacggtgt gaagatgaca cctccgccag ccccagtcac
     2941 tgtctggata tgaccgattt caatttcctc aaaggcgcgt ttgataatga cgatatcttc
     3001 tgagatggat gatttagcag actcatactt ttcagcaaaa gtattgagac tagttagttt
     3061 ataaggatta ttaatcaaat agttggaaat gacaaccatc cgatcacttc ttcttaattt
     3121 catttctatt tcctattcca tttttattca aaaaatcaaa aagcaaacta gaaagctggt
     3181 cgctggtggt tcaaaacact gttttgagat tgtcaataga actgacaaac cctgtaatat
     3241 acctgcatat atacatacga caaggcgata ctaccctagt ttgaagagat tttcgaagag
     3301 tattcatttt tgtcttttac ttattatacc atattcacat aaaaaaacga acattcttat
     3361 cctaaaaaat gctcattttt cttaaattat taatctaaat ctggtttata gaaggaacga
     3421 ttatccatag cgaagatttt attggtcatc tctcctttat ccaccaaagc aagagctgtt
     3481 gacatcatca tcatgcttgc atccagattg tcaatcatat ggataatctc tgcttccata
     3541 atgcgtggac ggactgggct tccatactca agcaagccgt ggtgactgag gatgacatga
     3601 cgaagcaaaa cgacttcttc cttggtatca tcgatgccga gttccataac tgtcttggta
     3661 atttcgctat caatgagagc gatatgtcca agaagattac ctcgcactgt gtactctgtc
     3721 tggtctggcc ccgtcaactc gataacctta gctaagtcat gcagcataat ccccgcatag
     3781 agtaagctct tattgagctg aggataaact tcgctaatag cgtctgccaa acgtaccatg
     3841 gtcgccgtat gataagccaa gcccgtttca aaggcatggt ggttggtctt ggcagctgga
     3901 taggagtaga attccttatc atacttggtg tagagatttc ggacaatccg ttgccagaca
     3961 ggattttcaa ttttgaaaat catttgcgac atgtagtcac gaatttcctt gacatcaact
     4021 ggtgacttga ccttgaaatc ggctgggtca ttgggttcac cagcttgagg caggcggaga
     4081 gtaatttgat tgacttgagg ggtattgtta taaacttctc ggcgtccttt catgtggaca
     4141 accttacctg cggtaaaggc ctcaatgtta tgaggttggg catcccagag cttcccatca
     4201 atctcgccac tatcatcttg gaaggtaaag gctaggtagt ttttcccagc tcgagtttgc
     4261 ctcaggtcag ctgatttgat taggtaaaag ccttcaaata gctcatcttt tttcatgtga
     4321 ctaatcttca tattcttcct cattttcttg aaaatggagt agatcaagcg caggctcgcc
     4381 ttctgacaac tcaatgtgac ggagcgtccg ctcgatagct atggtacgac ggtttaataa
     4441 ttcatcaata ttgccagagg catgttggag atgtttttgt gccttgacca gaataccacc
     4501 aaacttgcca aactcggtct tgacactggc aagagtcttg ctgatatggt cggcactctt
     4561 ttggatatta agggtcttga aaccaactga tagggagtta agaagggctg atagggtact
     4621 tggtcctgca acaataatct gttcttcccg tctcaaatca tcaaagaaga ccggattgcg
     4681 cacaatctct gaataaagac cttctgtcgg aacaaacaag attccaaagt tggttgtccg
     4741 aggcggtgct atgtacttgc tcttgatatc cttggcaaag cgcttgacgc ttgctaggag
     4801 tgacttacga cagcgttcaa tctcatcctt gtcacctgtc tcataggctt cttccaagcg
     4861 gtaataatct gccagtggaa acttagagtc aattggcaga tagacgtatt cttggtcgcc
     4921 ttgtccgggt aacttgatgg catactccac tcgttcacta gagttttcaa ccgttgcgta
     4981 ttctcgttcg tactgggcag gtgtcatgat gtcttcaata atttgcccca gttgcaattc
     5041 tcccagaatc cctcgcgtct tggttccaga gagaaccttg ttaagagctc cgacatcacg
     5101 ggcaactgtc tgcatttctc caaggccacg attgacagac tccagttgtt tagaaactgt
     5161 ctcaaaggaa gcctgtaagc gtgtctgcaa ggtcttttct agtttttcct cgaccgtctg
     5221 gcgcatttgt tccaaacgtt gctcatttga ttcctgcaag gcttggagac gttggtctgt
     5281 cttgtctcta gtttggagga gattatctgt catttcttga cggacttggg tcagaccttg
     5341 gtgcaattca atccgcactt cttgcaaacg gtcgctgaca accacttcca aatctttttg
     5401 gtctaactgg ctggcttgtc tggcttggtc aaagcggtaa tccaactggt ctgacaaatg
     5461 atctgcctga tcctccaagc tcttacttaa gtgtttctcc tgcctatcct gcctttgcca
     5521 aatcagaaaa agaccagcta ggttggcaat taataataga ataagtaaac tttccatcct
     5581 acctcctgtc cttgctatgc agtacgacca cataaccatc tgggcaagtt accgacactt
     5641 ccctatctat atattcgtta gaagcgtaca cttttttaaa gaaaaaattc tcctctgtca
     5701 actcatactt ggctccaaga atagtcagct ggctatcccg aactggcata aaggctagat
     5761 agtcgtagtc tgaacgaggt tctagctgac tggtcccttc tgaacaatag gcaatcaaat
     5821 tttgcccatc ctcaatttct atttgacgca tatagggtgc caacttagga ttgctaggta
     5881 gaaagacatt ggccaacata tggtcaatac ggccacccaa ggcaccgaaa atagtgacct
     5941 cagcctgagg attttgttca aagatggtta agagagccaa ttccagatct gtatcatcct
     6001 tttctggtcg tgcttggaca aaatactggg cacgtttttg aatcacctgt cgctcttctt
     6061 ccgtcacaga atcaaaatct ccgactgcta gagcaagagg taagtcttct tccaagaccc
     6121 agagcgagcc tcgatccacc ccaacaaaag catcaaaatc tgtccgataa tgaccgcggt
     6181 ttccgcctgc aaaaactgca accctagtcc agttgttttc tgagagtttg tactcgctca
     6241 ttgacttctc ccttaaagac ataggaacct gctacaaaaa cagtcgcacc agcttctttg
     6301 gcttgggcaa tagtttggtc atcaatccca ccatccactt cgatttcaaa gttcaaacct
     6361 ttttcctcac gaagagcaac caactcacga accttatcca tggtttctgg cagaaaggct
     6421 tgcccaccaa aacctggatt aaccgtcatg actaaaactt ggtcaactag atgaaggacg
     6481 tgcttgatgg cttcaactgg tgtgccagga ttgataacga ctgaaggctt aactccgagt
     6541 gaacgaattt tttggagggc gccatgaata tgaggtgttg cttctacatg gatactgatg
     6601 atgtctgcac ctgcacgcgc aaaatcttcc agatgatgct cagggtttga caccatcaag
     6661 tggcaatcga aaaccatctt actatgagga cgaaggctct cgaccacacc tgcaccaaaa
     6721 ctgatttgcg gtacaaaatg actgtccatg atatcgatat gggcatattc tgccccagtt
     6781 gcttctagac gtttgatttc acgttcaaag ttggcataat ctgctgccag aattgacgga
     6841 gcaatcttgt attgagacat aggtttctcc ttattttgga atttttttgc tgactttttt
     6901 ataggtttct ctacgatttt caatttcgct gaggaattgc aggtagttgt caaaacggaa
     6961 ggtggcaatg gtcccctctt ctacagctgg cttgacggca caagacggct catgggtatg
     7021 ggtacaagta cgaaacttac aatctcggct gacagtagca atctctggga aagcctgatt
     7081 gaggtcttca gcccttgata cttcatagtc cagagatgaa aagcctggtg tgtctgcgat
     7141 tttacccccg ttgagattgt aaaaactaac agctcgagtg gtatggcgac cgcgacctag
     7201 actgtctgaa atttctcccg tttcaagatt gaggtctggt acgagtttat tgagaagagt
     7261 tgacttccca acacctgtct gccccataaa gaccgtaacc ttgcctgtta acaaagacag
     7321 gagttcctct ttactggtca caaagtcata gccgatgtca ccataggtct gccggtaaaa
     7381 atccagttct cccctatctt ccaacaaatc cattttggaa atatagacaa tgggatggat
     7441 gcccttgtgc tccaaaagaa ccaagaaacg atccagcaaa ttgctgttaa aatcaggttc
     7501 cttgacggac atgattacta cagcttgatc gatattgaca ataggcggac gaaccagact
     7561 gtttttccgt tcgtgaattt tgaggatata gccttctgaa ttttcctcgg cagagaaatc
     7621 tacccagtcc ccaacataag gggtatggcc ttttttacgg aaattcccac gcgcgcgtgt
     7681 ttgataaacc tggccatcac tctccacata gtagaaacct gccaaggctt taatgatttg
     7741 tccctgcatc ttagagtcct tgccctttaa gtgcgtctgc tagaccggca aattctgcca
     7801 agctgagagc ttccccacgc acacttggtg acaagcctgc ctggtccaaa gccttggtca
     7861 gcttgtcctt gacctcttca gtcttaccaa agtaacctgt caagttattc cacaaggtct
     7921 tgcggcgatg ggtaaaacta gccttggaaa ccttaaagaa aaagttctca tcttctactg
     7981 ctacggctgg ctctggacga cgcaccattt tcaagatggc tgaatccaca tttggcgctg
     8041 gcacaaagac cgtacgaggc acgataaagg caaccttggc tgtcatgtaa tactgcacgg
     8101 cgatagacaa gctaccgtaa gccttggtgt taggctgggc tgaaatgcgg tccgctactt
     8161 ctttctgcat catgaccaca aactcacaaa aaggaatgcc actctcaatc aagtgcatga
     8221 gaataggcgt cgtgatgtag taaggcaaat tagccactac cttgattggc aggtcaggat
     8281 ttttaaaatt ctggatatgt tgcgccaaat caaccttgag aatatcttcg ttaactacgg
     8341 tcacattatc aaaatcacgc agggtatctg ccaaaattgg caccaaacgg tggtcaatct
     8401 caaaagccat gacttgggct gcacgctcag ccaaaaattc tgtcaaggca ccaatacctg
     8461 gcccgatttc gatgacattg acctgatcat caatttcagc cgtatccaca attttttgaa
     8521 ggatattggt atccgtcaaa aaattttgcc caaaggactt tttaaaggta aaaccgtgac
     8581 gctccagcac tgccttggtc acgctataat ctgcaattct catctattct cttttctatt
     8641 atctgttact actattgtaa cacattcccc ttgtattttg ggaatgaaaa tcataccaaa
     8701 aaactatctt tcctcatgaa gaaagatagt cttggaaatc tttaaaagtg gccttagcag
     8761 ttctctcgaa acatgcgttc aaaaaaatca gcttcttgat aacttcgatt ttcaggtagg
     8821 gtcaaatcca catcctcctc cacatcatcc actgtcagtt caaccgtctg aggtaaattt
     8881 ttcaaacgat aatgcttttg cctttgccct tcaatactag caaaatcaag caaatagcca
     8941 tgcactcgga tttgaaccaa aaggagatga ttggtcatat tttccatgat gaggatatct
     9001 tctaaaccac ctctggcact aggataatca gataccctgc gaatacggat tttttcacac
     9061 atgagcaagt ttcctcatat caatgatttc atcagcctta ttccagacta ggggattatg
     9121 ggtcgcaatg atgataattc gattttcatc tttcaaatcc accaagagat tcataacctc
     9181 ctctgaattt tcaggatcaa gagctgctgt tggttcatct gccaaaatca agggtggatt
     9241 tttcaaaata gtcttagcaa gggcaactcg ttgggcctct cccccagata aagtatagat
     9301 tttttgttct aaatccaaat accctagatt aactttttct aaagccccca cttgcctttc
     9361 caaacgttct acttttgaga ttttctgacc aacaaaaccc aaatccaaat tttctttgat
     9421 tgattggttt tctaagaggc caaaattttg aaagagatag cccatctgat ctcgaaaata
     9481 ctcacgagtg ggaatggttt ttaaatcttt cccctgatag agaacccttc ctccatctat
     9541 cttttctagc tttcccaaga tattcagcag cgtcgtcttt ccgcttccac tctttccgat
     9601 taaggcataa accttgccct tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc
     9661 attaaatttc ttttccaatc cttgaatatc aatcatctta ttttcctttc aatactgcca
     9721 tgctaccagc ttcttctttt ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa
     9781 acaaagctac aactagagcg ctaatcaaac catctcttgt caaaatacta gataggacta
     9841 ggccaagcaa gagaactcct ccttgcgcca gtaaatactt gccatgaagc tcatagattg
     9901 tcataccagc aagacgttta atcataagct cccgtctgaa ctgctcaaaa tagagaagat
     9961 tcatggaatc aaataacaag atagccgtag acagggtcaa aatcgtccca ataaggagag
    10021 agtaaaactc cacccgtttg tcatttagta ccttggcaaa aaatagctgg ctttttacca
    10081 agtaagaaac cttgtgatac agaccttgct cttttagagc tgtgatgctg tctccatatc
    10141 gatctagttt caaggcacta ttagccgtag ttccccacaa catccctgca acaggtcttg
    10201 ttccagtcgc ttgcggcgtt agaactacaa taatcggatc ttttaggtac tggcgtgttg
    10261 tcttgtaccc atcattatag aggaaacgtt cctgtcctgt ttctgtaaaa gctagcctta
    10321 cctgtgggaa gtagtgtttc tgactcgtca cttctacact ttcagatgaa aagttttgca
    10381 ggtaatctgt aaacaatcct tggtagtagg cagactgctc ccgcaagctc tcaggcaaga
    10441 tcagcccaaa ctctccctca gacaagtttt gcatcttgtc aataaactct gaagaaacgg
    10501 taatcttttc ttctatcaga tagcgcggcg agacatagat aacattccct gacggtgtgt
    10561 agtcactgag acgattgcca tctaggtcca cttctgctcc atctgagaaa ttgtcaacat
    10621 tgctcataat ataaaaagag tctgtattgg ctaaccgttc ttcagtaaat gtctgccact
    10681 cacgattatc cttacgcgtt ccttcttcat cggcaaatgc actagaccaa ccaaaggata
    10741 gacggtaacg gtctgaggac tggctccatt tattgctagc tctctccatt tcctgcattt
    10801 cacggtagtg gggtaggaga gctgtcgcac tcgatccgac caccaataca gctaagagtt
    10861 gccccaccat catcaatgtc atcatccgtt tgagagggag tttccctttc aatagatcca
    10921 ccagactatt ttcctgtaaa ccaagtagat agacgacact tagtaaggta gaaatccctg
    10981 ccagggtcaa tccataaagt agaagagcaa tgatgaccag ttgcaccgtt gccataaaca
    11041 aggcaccttg ataccagaga atccccaatc ccaaaagact ggataccagc actgagcaga
    11101 taagctgtct cacatcttct aacactggtc tgagagcaac tccaaacaag ctctcaccag
    11161 ctattaagcg aatccctgcc tgacgaaggg atttgatccg ataaatcagg gtcagactca
    11221 taaaggtcag cagaaaaata gctaaactca gtagcaccat aggggtggcc gtcaatagta
    11281 agactatcga aaatggatct tctccattcg aaacaaagcc ttgataacca agctctttca
    11341 aggtggtctg taagctcact ccatccaaac ttcctgacac aatcaagtaa gaccctaata
    11401 aatcactcgt ttctgcactc tccttggagg aaatggtcag accttctgga agctttccct
    11461 caccataagt ggcataggta aagcgtgttt ctccagcttc atttggctca acaatccgac
    11521 gggcgatgag actattatgc tctaccgcca agtgactcaa agcctctgtc acctcttcgc
    11581 ggctagctac tggttgattt atcatcattc ctgtcacatc aacagaagga tagttaccaa
    11641 ataaaatctc ttctcgatgg tcaacggaag ttatcaccat ataaagcgat accaatacca
    11701 ttgaaatcaa aataaataaa cgtttcatca tttcctccaa aaagttactt ggtcacttag
    11761 tgagaaggtg accaagtaaa gctaaacaat agggctatac cattctaaac attatagtag
    11821 aatgcaactt tctctcccca agaagtacga atccatgcac gagaagtccc tccagcacca
    11881 gcatatccct tgtcagatga accagttttt ctgctaacaa ctgttgaact atggtatttt
    11941 gaagggtgat agtagtttga gtaagcacca ccgttacctg aaccataagt ccaaacacca
    12001 ccttctgggt attgaacggc tgcagaggca actgatacac ctccacctaa tgttgctgca
    12061 atgctcgcta caagagctaa ctttttaact gtttgtttca tattgatact cctctatttt
    12121 tgattacaag attgttgagt tacttgctcc tctttccatt atcaacgttg atactattat
    12181 attaccaaat gatattctaa aattatttgt ttttctctaa attgtcaaaa tagcaccctg
    12241 aaatgaactt ttatagtcat tatactccat ctttatcaca ctatcaagga catcaatgtc
    12301 cttaaaatct aactatttca tattattttt agcttatatc taaaaaaaca gttctaaaga
    12361 cgaactttag aactgttttg atacgaggac aaggacattt ttgtcactga ttcactatgt
    12421 ttataaatat tttttgacat cctcttgcca ttcctctgtc aatttcttta ctagaaattc
    12481 atctccaatt agcttcgcaa atgttttaga agactgataa aatgattcag ctaaactaaa
    12541 atctctttct actcttaatg cttgcttcca caaaaacata aatacaagag gtttcttttg
    12601 ataatcttga gttttatcca taatttcttg taaacacgat agataatcat taaaacaatc
    12661 agttactcct accttttcaa gacaacacat tcctgaaata agagtatctc taattataaa
    12721 gtaattctct atttgagtta ccttcttctg ttccaaaaga aagagcatta gcttttcgat
    12781 ttgatttata aatttggcaa gatcttttct aatgagcatt tgataaaaaa acaaacgaat
    12841 caacaacata tcatttattg aataagcttc tttttctata atctgaggca tatgttcctc
    12901 aagtattaac tctgcatatt caggccttct agttctagaa gtatccaaac acgcctgcaa
    12961 tacttcacat gctaattgtt cttctttagg aagattatca aagtatgttt tataaatctc
    13021 ttccaaacac gcttccttct tatcgtactc ctcttcttta ccatagattg gttcacgtaa
    13081 aatctggtat ttcaattcta aataagcaga aggaagagct gaaaaatccg gcataaggct
    13141 ataaactgga actcctagcc ggcgagcaat ataggctaac ttgggcaaac tcggttgcga
    13201 agctccactt tcaattcgcg acagttgacg aactgtcagt tcttgctcat ctccacaaaa
    13261 atctggacga ctaattcctt tttctatccg aatctcttta attttttgac caattaacat
    13321 cagacgcctc ctcttctacc tgcttcgaaa aatactgtga aacttaaaaa attgtaacgg
    13381 tcacatcttt cctactcata agatttcata gcttcttcca cttctgccaa agtaacccca
    13441 aacaactcta ggcgtttgag gagttgcttg ccgttagaat agccgattcg gagagtctct
    13501 ccgagatatt ctctacgctt acggctgtct gcccctgcta gaaaaccaag gcgaatcaaa
    13561 tcgctacgac taatgtcaaa ctgactctca tgttcaaatt gttctgtcac ctgagctaga
    13621 gccgttttca ggtcttcata gctggcatgc tcaattccca gagaacgccc cttggtcttg
    13681 gacttgggaa cagcttcatc tcgcttgaga aaggcatgct gaactgttgg aatggccgtc
    13741 ataatcatgc gccgaatccg ctccccatta aaatctgggt ctgtaaagac aatgactcca
    13801 tgacgttggt gtagacgctg aatccgctct atgtcctggt cattgatggc agaacctcga
    13861 gtctcatagg tctccacatc gaaataacgc ttgagattga ccgtatcatc acgaccttca
    13921 accacgataa cttgggaaat tctctctttc attacttgct gtccaatcca aaaatgcgtt
    13981 ctgcatttgc agtcgttgct accgccagct cttctgtcgt cataccacgc aagtcagcga
    14041 taaagtcgac cacatagcga gtataggctg ttttattttc acgaccacgc ttgggtacag
    14101 gtgctaagta aggcgcatct gtttctacca acatcttgtc caaaggtaac tctttagctg
    14161 cttcttggag gtcagttgcc ttcttgaagg tcaccactcc tgagaaggaa atggtcatac
    14221 caagatccac aaacttctct gcccactcaa gcgtccctga aaatgaatgc atgataccac
    14281 cacgaggacc aacgccctca ctcttgataa tctcataggt atcttccagc gcatcacggg
    14341 tatggacaac aaaaggcaaa tccaagtcct tagatagctg aatctgacgg cgaaaaacct
    14401 gctcctgcac ctctttgggc gctgtcatcc aatggtagtc taagccaatt tcacctaaag
    14461 ccacaacctt ggaatgtttt aacttatcca acaagtaagc ctcaacttcc tctgtataag
    14521 taccagcttc tgtaggatgc caaccaatag tcgcatagag ctgctcatac tcatctacca
    14581 actccaaggc atgctcaatc gtcggtttat caaaaccaac aatattcatc tgtgtcacac
    14641 ccatctcagc agccaaggca atttcttctg cctcacgacc tgcaaattct tctacattca
    14701 agtgtgtatg tgtatcaaaa atcatctctt ctaacctcgt tttctatcct tctattatac
    14761 caaaaaagag gaggggcacc taatttttcg gtttcccctc ctctcttcaa tagagagcta
    14821 ttctgctatc ttttctatcc gatattgccc atctcctatt ccacagttag agacagaaga
    14881 gattggctac attgatagaa tattcctatt cagctaaagt atgtgattat cttgggttct
    14941 cacttttctc acccatcact aggattgatg acttctcaaa atccccctta taatctaact
    15001 ttaagtagag aatagaattt tctagctgtt ctattttcta cgtctagtct ttcttcctag
    15061 caaagcaaaa ccacttgttg ccaccactag accaagacta gcaagtgctg cacttgatgc
    15121 tgaacctgtg ttaggtaatt gtttgccagc aggtgactgg taggtaacat cttgcattgt
    15181 tcctgcagtt gcttgcggtg cacttgttgt cttaggagca gcattaggag ccactggtct
    15241 cttaggaact gtaaccatgg caatggcttg cactccaatc gtttctgctt ccttcacatc
    15301 ttccatagtt ttcgcatttt caatctcttt gagagctgct tgtttttctg cttccactct
    15361 tgctaaaagt tctgcttttt ctttatcaga aagcggtgcg cctttgattt catcctgctt
    15421 gttcttggct gctttttcaa tggcattttt agctgattct ttttcagtag ctaattgctt
    15481 agaagcttgt gattgagctg agttttgtga acctgtgtga gctgatccac ccgcctggct
    15541 accaccgcct tcattcgcat tagcatctga gcttccagta ttgcctccct tatctccacc
    15601 tggtgtattt tctagcttat actctggtgt agcttcttga gttacagatt cacctttcgc
    15661 agattgttga actgtatctt ttcctagaat cgtcactact gaaccatctg ggaatgtgat
    15721 tgtcgctgtg ccatctccag ctacttcaac tttatagtaa aataaaataa taacaggaca
    15781 aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaaacagag gtgtactatt
    15841 ctagtttcaa tctactataa catcgcttcc gaatccattt gcatctactg aactttttta
    15901 caaaaataaa aatcagtaga ctcgagttcc tactgatttt tgatagaatt cgtttggatt
    15961 atgcagccaa aactttgcgt cctttacgac gacgagctgc caatacgcga cgaccatttt
    16021 tagttgacat acggttacgg aatccgtgtt tgcgcgcacg acgaagttta cttggttgat
    16081 aagtacgttt cacgatgaat acctcctcat agattttgta ttcgtttagc cggctataaa
    16141 gtgatcagtt actaaacata ctttactatt ctatctgatt ctttcacttt tgtcaatagc
    16201 cctaggcaaa tgtttccagc tttttcgaat gcaagcccta tctacgatac tgtttcaaga
    16261 aacgagtcat cttttcttgg atttgggcta actcatcaac acgaggaagg taaacgatac
    16321 ggaagtggtc tggttcctgc cagttaaagc ctcgaccatg aaccaagaga accttttcct
    16381 gcttcaagaa atcaaggaca aactgctcat catcatcgat acggtacata ttgcggtcga
    16441 tttttgggaa gatatagagc cccgccttgg gtttaacggc agacaaacct ggaatatctt
    16501 gaatggcatt atagatgaaa tttctttgct cgtagattcg tccaccagga agaagcaatt
    16561 catcgactga ttggtgaccc cccaaggaag tttgtacgac ttgttgggcc aaaacgttag
    16621 agcaaaggcg catattggac agcatattga gcccttcgat atagccctta acatgagtct
    16681 tagggccaga caagaccatc caacccacac ggaaacctgc tatgcggtgg gattttgaca
    16741 gaccattcat gctgacacag aagacatctg gtgccaagct cgccacaggc gtatgcacat
    16801 gtccgtccat taccatgcgg tcatagattt catccgcaaa gataatcaaa tcgttttgac
    16861 gggcaatctc aataatctcc agcaagagtt ccttaggata aagggctcca gttgggttat
    16921 ttggattgat aaggacaatt gccttggtat tggaagtgat ttttgacttg atatcgtcaa
    16981 tatctgggta ccattccaca gcttcatcac agatatagtg aacggcattt cctccagcta
    17041 ggctgacagc cgccgtccat agaggatagt ctggcattgg cactaagacc tcatccccat
    17101 tgtccaaaag cccctgcatg gacatgacaa tcaactcact gacaccattt ccaaggtaaa
    17161 tatcatcaat atctacgttt gggaatttct tcagctggca atactgcatg atggccttac
    17221 gggctgagaa aatccctttg gagtcagaat agccttcact atcacgcgca ttcataatca
    17281 agtcatgaat gacctcgtct ggcgctgtaa agccaaattc tgctggattt cctgtattca
    17341 gacgtaaaat cttttctcca ttcgctcgca tccgcatggc ttcttccaat acaggaccac
    17401 ggatatcata agcaacatgc tctaacttac tagacttgtt atattctttc atcttgtttc
    17461 ctcaattcat caggatagta acattatacc actagaaaga gaatgcgaca agtttactga
    17521 aatgtgttac tagtttcgta tagaagaaaa accttgctaa aggcgaggtt aagaacgtag
    17581 agatagcagg tattttgcaa agacacatca cataccaaaa gataaaccta gaaaaaagca
    17641 agcctagaaa ggagtcataa agaagattaa acatgaggaa aagcccccat atcatcaagt
    17701 aatcccaacg cccacttcgt tttgcaacta gaaataagat tagatggtag agtacatgaa
    17761 aaactaaaaa tccaataaaa cttggataaa gaagcggtac cagactctct aattgacaga
    17821 tcatgatcac ttctaccaag actgaaacta ggataattcc ataataaagg aaatttgatt
    17881 tttgaaaaga gtttttcatc attctccctt ccttcacttc tttcctgcta tcctttcttt
    17941 tattttatca tatatttata tagagtttaa gccctaatat tcttttgaaa aatacttttt
    18001 ttgctttact tctatagtga aaaggtttac aattatagta agaaaatttc aggaggtttc
    18061 attatggcac aacgttacca aaatatcatg gtcgcaatcg atggttctaa ggaagcggac
    18121 ttggcttttg tcaagggagt tcattctgct ctacgaaacg acgctaaact caccatcgca
    18181 catgtcattg acacacgcgc tctccaaagc gtatccacct ttgatgctga agtttacgaa
    18241 gaactccaag tcgacgctga aagtctgatg aaagagtacg aaaaacgtgc taaagatgct
    18301 ggggtagcag atgttcatat cgtcattgaa atgggaaatc caaagaccct gctagcacgt
    18361 actattccag atgccgagga agtggacctc atcctcgttg gcgcaactgg tctcaacgcc
    18421 tttgaacgcc tcttggtcgg ctcttcatct gaatacatac tccgccatgc taaggtcgat
    18481 ttgctggttg tgagagaaca agaaaaaacc ttataatcac aaagaaaagg agcccctagc
    18541 tcctttttgt ttacgattta tttctctctt tatggcgttc gtaagccttg agctggcgct
    18601 gcagttcctt tttaatagca ggttctggag catatttttc ttcccaatta tctggtttta
    18661 agattttatg ggtcactgga tcaaaatgag ccttgccatc tggaaaaatt ttccccatat
    18721 tggcctgatg gacaatatca aaaatacgtt ctgggtccac ccccatcaag acaaaactgc
    18781 cgtaggtgaa gtaaagcgtg tcaatcaagg catccacttg ccctatcaaa tcttgctgag
    18841 caggtgtctt cttggctact ttatctgctg ccttatcaag ggcctgatga agttgcgata
    18901 cagcttgacc aaaatcttct tcagaaggac tggctgctcg aacaaactcc accaattctt
    18961 ctattttaaa accagcccta tgggttgcac cctctaaatc ccaagctcga ggttcttctt
    19021 gggttcgttc atccatcatg tggtggaagg tcttgacctt attgaaatga tagtcacggc
    19081 tgacaaagac tttttctgaa gacaaaacac caaaatgttc caaggccttg tggattccat
    19141 cttgttgatt gctagtggta atgtgcttgg cagcttcctt gacactgcta ctaccatttc
    19201 ccatagcgac cgacatacca acgccagcca gcatttcaag atcattatct gagtcaccaa
    19261 aagccatgac ttggttgagg tcaaagccat attctttccc aactcggcga atgccttcta
    19321 atttagaatt tccctgattg atgacatccg atgcaaaagg attgctacgt gtcaatttca
    19381 agtcttcaaa atcagctgcc gccttctcag attcttctgg tgtcatcagc atcaaaactt
    19441 ggtagatagg ctgattcatc aggtgaagca ggtcctcttc cttttgggga acaaccttgc
    19501 tgaccatgcg attaaaagac tgactcaccg tccgagttaa aacagaggga acgaagcgac
    19561 taattcgttg ggaaaaagaa cccagaccaa aggacatgat tttagaaccc aacatggcat
    19621 ccttggtccc tagagcaatc tccgtgccct cttttttagc atagctaatt agatggcgca
    19681 aatgtaactt ggaaataggg ctcgtgaaca agactctgtc tttactaaag atatactggc
    19741 cattataggt taccgcaaaa tccagatcca aatcgtccat caattcctta acaaaaaaag
    19801 gtcctcgccc tgtcgctacg ccaactagta ccccttgttc tttgacaatc ttaatcgcat
    19861 ccttagtgga tttcaaaaca ctcttgcgat tgttgaccaa ggttccatcg atatcaaaaa
    19921 aaacagcttt gacttccatc ctatcccaat ctcccctttt gtgatacaat gattatacca
    19981 catttcagaa agagtgagta aatcatgcct aagaaaatcc ttgttttaca tacgggtgga
    20041 actatttcca tgcaggccga tgcttctggc gctgttgtga cgagttcaga taatcccatg
    20101 aaccatgtgt ccaacccact tgaaggaatc caagtccacg ccttggactt ttttaacctt
    20161 ccaagtccct atatcaaacc caaacatatg ctggtcctct accagaaaat taaagaggaa
    20221 gcagataact acgatggagt ggtgatcaca cacggaaccg atactttaga ggaaacagcc
    20281 tatttccttg ataccatgga agttccccat atgcctatcg ttctaacagg agccatgcgt
    20341 agctccaatg agctcggtag tgatggtgtt tataattacc taagtgcttt acgagtggcc
    20401 agcgatgaca gggctgctga caaaggagtt ttggtcgtta tgaacgatga aatccacgct
    20461 gccaagtatg tcaccaaaac acatacgact aatgtcagca ccttccagac tccaacacat
    20521 ggcccccttg gtctcatcat gaaacaggaa atcctctact tcaaaacagc tgaacctcgt
    20581 gttcgctttg accttgatca catacaaggt ttagtcccta tcatctcggc ttatgctggt
    20641 atgacagatg agctgattga tatgctggat ttagaacact tggacggttt gattatccaa
    20701 gccttcggag ctggtaatat tcccaaagaa acggctcaaa aattagaaag ccttctgcaa
    20761 aaaggaattc cagtcgctct ggtatcacga tgctttaacg gtattgccga gcctgtttat
    20821 gcataccagg gtgggggcgt acagttgcaa aaagcaggcg ttttctttgt taaagaactc
    20881 aacgcccaaa aagctcgctt gaaactcctc atcgccctca atgccggact aacaggacag
    20941 gctttgaaag actatatgga aggctaatac tcttcgaaaa tctctgcaaa ccacgtcacg
    21001 tcgccttacc gtatgtatgg ttactgactt cgtcagttct atctacaacc tcaaaaacat
    21061 gttttgagct gacttcgtta gtttcatcta caacctcaaa aacatgtttt gagctgactt
    21121 cgttagtttc atctacaacc tcaaaaacat gttttgagct gacttcgtca gttctatctg
    21181 caacctcaaa gcagtgcttt gagctgactt cgtcagttct atctacaacc tcaaaacagt
    21241 gtgttgcgca gcctttaatc agccgcctag tccgctctat ggtattcatt aagtcaacat
    21301 ctcttgttta agagcaccaa atcaggaaat cttctcgatt ccctgatttt ttctatttac
    21361 gttttcgtgt tgagctacgt tctgtcaaac catgaggtaa gagaacttca cgttcttcca
    21421 actcttcctt atgcataatc ttggtcaaca tacgcatact aatggcacca aggtcataaa
    21481 gaggttgggc aatcgttgtc aagtttggac gggtaaagcg tgagatttgt gaatcatcac
    21541 tagtaataat ttcaaaatct tctggcacag aaacaccctt atcagccaaa ccgttcaaga
    21601 ctcctgctgc caactcatca cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac
    21661 gctctgctaa ggcgtaacca tcatcatagc tatatttaga ttcaaatacc aaaccctcac
    21721 tataagtgat tcctgctttt ttcaaggttt ccttgtagcc aactaaacga accttaccat
    21781 tgatgtcatc cactagcgga ccgctaacga aagcaatacg ctcattttct ttagcaaggt
    21841 aactcactgc atcaattgtt gcttgcttat agtcaatatt gacacttggc aactggtgct
    21901 caacatcgac agttcctgcg agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa
    21961 ttttatctgt caagtgatac cccatataga taatgccatc tacctgcttt gaaaagaggg
    22021 tattgacaac agaaacttct ttctcgttat cttcatcgct attagctagg acaatattgt
    22081 acttgtacat ttctgcaata tcatcaatcc ccttagccaa actcgaaaaa taaccattgg
    22141 taatatttgg aatcacgaca ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa
    22201 ctgcatttgg acgataatcc aaacgatcaa ttacctctag cactttttta cgggtattct
    22261 cttttacatt tttattgcca ttgaccacac ggctgaccgt cgccatggaa acacctgctt
    22321 cacgagcgac atcataaatg gttactgtat catctgcatt cattcctttt cctgtccttt
    22381 ctatctcaca cattctttta caagtagagg tactgattga agctctatat ctacttacaa
    22441 aagtgaagat gtgaaaattt cgttttcata tttctactta ttccattcta tcactaattg
    22501 taaacacttt caagtgtttt ttgaagattg attgaaaaaa tttcatagaa aacctaggtt
    22561 tagctccttg ctaccacctt agactaaaca aaaaggagga aactaagccc tcctaaagtt
    22621 atagtaaaat gaaataagaa caggataaat cgatcaggac agtcaaatcg atttctaaca
    22681 atgttttaga agtagaggtg tactattcta gtttcaatct actataggta ttgttccatt
    22741 cactaccgtc aattttagca catagtcttc atgaaaatat tatatcatca taaccaacca
    22801 gattctttcg cgatattagc tgcctctgtt cgattacctg catctagttt cgaaagaata
    22861 ttggtgacat agtttcggac tgttccgttg gatagataaa gtttgtctgc aatttcttgg
    22921 ttagagaagc cctgagcaat tccctttaaa actgcgattt cttgctccgt taatggattg
    22981 ggatgcatca tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg
    23041 gtgtgcaagg tttgcatgag gtctgcaatg tttctttctt ttaatacata agcatctact
    23101 ccagccttga ccgcacgttc aaaataccca ggacgcttga aggtcgtcac cacaaccacc
    23161 tttgtttcaa gcttttctgc tcgtatccac tccaagactt caagacctgt cttaacaggc
    23221 atttctacgt caaggatggc gatatctaca gactcctttt ctaatagttg gattgcttct
    23281 tgcccattct tggcttgaaa gacagactct acatccggtt gaagcatgag caactggcac
    23341 atggcatctc gcaacatact ttgatcttct gcgactaata ctttcatcta ctttctctcc
    23401 ttataaagta gtcgaacctg cacttcagtt ggatgtttct gactgattac acttacttct
    23461 cctgaaaatg gaaaaacacg atttcggact gtatggagct catccccgct tatagaggca
    23521 aagccacagc catcatctct cactgttaga atgagttctt tctctgtccg ttctaatttc
    23581 aagtagactt tagacgcttt agcatgtttg atgatattgg tcactaattc aagcaaaatc
    23641 atggaagccg ttgactccaa ttcctgagtt aagctagact tgtccaagtg attctcaact
    23701 tgaacctcaa ttccagcaat ttctaacatc tttttcacag tctctagttc ggatgtcaaa
    23761 gttctagact taagattttc cacaatggtt cgcacttcat tcatggaatc cttgctgatc
    23821 tggtgaattt cttttaattc cttttccacc tgtggataag cctccatctg aaataactgc
    23881 aaggctaaat ctgtcttgac actcagcata gcaaaggtat gtcccagact atcatgcaaa
    23941 tcctgaccga tacgactacg ttcattttca gcaagcaata gatttatctg agcattttgc
    24001 ttgacctgag cttctttcaa atcctcgaca atacgaatcc gaaccaatcc aaaagtcatt
    24061 aaatcgacaa aagtaagaat tacaagtaga tagaatagaa actcaacttc gattctctga
    24121 aaaatcaaca gttgccccac aacaaggact tgagcaagaa gaaaagtcca gacatgtaaa
    24181 gactttaaac tacgtacgct gaaatgataa cttaagagat tggataggaa aaagaaaaac
    24241 cagatataat taacagcaac aaaggcagta ttcccaacta cataagtcag catgaggccc
    24301 caatatagcc aagataggcg ctggctctta gttgttaaaa cacccaaata tgccactaca
    24361 aatagaatat caatcaataa atgccaggca gaaagccacc cagtcactac agacaggatg
    24421 gggaaaatca taaaaattaa actgatccaa aacatataat gtattctttt cagtctttca
    24481 agcattaagc attctcctta tgaccttgaa ggtaaatagt caaaccaaat aaaactgctg
    24541 aaaaaacaag tagataaact gtggctgata gattgattcc accctcattt aagaaggtct
    24601 tgattaattc catcaactga taacttggta aacgcttccc gattgcttgc atccagtctg
    24661 gaaataaaga gacgggcatc cagagtccgc ctaaaacagc caatcctaga taaagaagat
    24721 tgcccacgac agacatcagc tgactagttg gtaacagcgt caaggttaag ccaagtgcta
    24781 caaaagcaat acttcccaaa atcagcaaaa tcgcagctcc aacccatttt actagaggca
    24841 tgtctacacc tcttacaaaa tgtccaactg taaaaacaac cagaattgag accaaataat
    24901 caaccagcat acttgttatc tttgatagat aatattctac catatttact gggctatgac
    24961 gtaatatttt ctgccagttg ttcatcttgt cggtatgtaa gacagctggg aatgaaaaga
    25021 tagcggtcga catcatggaa aagccagtca tggagatgag gtaatcacgc ataaaattcg
    25081 cgggtccacc tggtgtgtcc tggtacatgc cagaaaagaa tagatagaag gctgtcggca
    25141 tccctactga caatagataa tagatcaatt gtcgtttggt caataaaaat tctatcttac
    25201 taagtgctag ccatcgtttc atcttagtta tctcccttct gcgtttcttc aaagattgta
    25261 tccaacaaac tacgattatt aacttcaatt tcttgtatgc cacatcctgc ttgaactaac
    25321 agttcccaaa aagcatctgc ttcgcgtgtg actacttgta gagcatcctg tttttgtgac
    25381 cagttttcaa ccaagttaga ctgctcaatg acttccttgt atgccagagg aaggataaaa
    25441 tgcttttcaa ttccctcact acgcatagct agaggcgtcg tatcacgaat caactctccc
    25501 ttatttaaga gcaaaatgcg gtctgcagtg tgttccactt cctcaatata atgggacgaa
    25561 tagagaatgg tgactccttg cgcttttaac tcctggacaa tttcccaaaa acgttgacga
    25621 gttgaggtat ccatggacgc agtaggctca tctaaaaaaa caatctttgg tcgcccaatt
    25681 aaggtcaaga cgaaagaaaa gagacgcttt tgaccgcctg ataatttttc tgccaactgt
    25741 tctttttgtt gcttgacaaa ctgcaatagt tgatcaactt cctgattgct caaaggattt
    25801 ggatagatac gttgaaagaa agcaatcaac tctttaactt ttaatttctg aacgattaca
    25861 ttttcttgag ggaggtaagc cctagtatag tctaacttag aactcgtcac tggtaaacct
    25921 tgaatagata cttgaccgct tgtgaccagt ttatctccaa gcaaacaatc taagagtgtt
    25981 gtctttccgg caccatttgg accaattaag gcaacacatt caccatcgtt gatttcaaag
    26041 gagatgttcc gcaaaatttc cttgtctttt attttcttac tcaatttttc aactttaacc
    26101 acagtcatga gactctcctt tcaaccactc cattcccata gggaaaacga cgaaaatcat
    26161 aaatccaaac cccaaagcac cacgaatgaa ttggcgaagc aaggcttgat caaaccaatc
    26221 agtaaacatt tccactaacc ataccaagag tgacaggccg ataaagaaat agatgatccc
    26281 tttcttcatt cctcaaactc ctttttcaca tctctgacta atttcaaacc ttctctaaca
    26341 agccaagaca tgattccaaa gccagcaaag atctttcaag gaaaatggta gaaatcctca
    26401 tccaatcccg aaaacatgag ataggtcata actcctgcta ctactaaact tactgcgata
    26461 atcattttat ttctcatctc ttcttccccc atttcatact acaattatag tcttttaaaa
    26521 tcagaggagg cagaagcttc tgtcactaga aaatatgaca aatgtcataa aaaattctgt
    26581 tcaaaacaag caagatacac tatacaataa aacacaatca gaaaaatcta aggcaacttc
    26641 ctcaaaagag atatcaaacc caattcacac cataatgtaa actaatactt atttaaaatc
    26701 aaaaagagta gaaattttta tcagacaaac acatatatag tgtattgaat ctataacagt
    26761 agggcttaaa tactaaaata tttctataaa ttaatttaac tttcctgata gagctgttca
    26821 tatcttattt caattctcta tattatacgt tgaacaaaac ccttctattg ctttcttaaa
    26881 aatttataag agttataaaa tctgttaaat ttcaatgtgt atacctaaac tacggtattt
    26941 attgaaaaga ctggggacaa aaagtatacg ctgccaaaat gaattactga aaatcaaaaa
    27001 agagagaacc aaactgattc cctcttaatg tatataatat ctagttttaa aaatacacac
    27061 tcacatatct ctgt
//
LOCUS       DBEROT010000031        26289 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.31, whole genome shotgun sequence.
ACCESSION   DBEROT010000031 DBEROT010000000
VERSION     DBEROT010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.31"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..1259
                     /locus_tag="ACL8CG_001488"
     CDS             <1..1259
                     /locus_tag="ACL8CG_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGS1344063.1"
                     /translation="FIIKTPQKLDFFCLTFGVSTLWLLNHYHYQDSCKNAEGGLILSR
                     YAGPGSHRYPVGFSGDTIISWNSLRFQPYFTATASNIGYSWWSHDIGGHMLGDYDEEL
                     QTRWLQFGVFSPITRLHSSRSPFNSKEPWFFSETTSKIMKKYLRLRHQMIPYLYTMNV
                     KTHEEGAPLISPIYYFYPENNESYNVPNQYFFGTELMVAPIVEKMDLTFQSAKVDVWF
                     PEGEWYDFFSEKKYTGGVKLSVYRDISTTPVFAKSGAIIPLVGSEIGMGVDLPEVVDW
                     YVFPGKQHSFEMLEDQNGQRYKTRLSIDWEMGMVELALQGDSSIVPSNRKHRIHFKGT
                     NVSIIELPNKNDTAKFEWKDNKRTSLNDEVFRLLKTASLPYELKDRLLNQFINAKNSH
                     DLMNILHHQDKELRGSLLEMIFTSQN"
     gene            complement(1481..1957)
                     /locus_tag="ACL8CG_001489"
     CDS             complement(1481..1957)
                     /locus_tag="ACL8CG_001489"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGS1344064.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFSKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            2180..5383
                     /locus_tag="ACL8CG_001490"
                     /pseudo
     CDS             2180..5383
                     /locus_tag="ACL8CG_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            5731..6107
                     /gene="tnpA"
                     /locus_tag="ACL8CG_001491"
                     /pseudo
     CDS             5731..6107
                     /gene="tnpA"
                     /locus_tag="ACL8CG_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(6495..7124)
                     /locus_tag="ACL8CG_001492"
     CDS             complement(6495..7124)
                     /locus_tag="ACL8CG_001492"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGS1344065.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(7134..8135)
                     /locus_tag="ACL8CG_001493"
     CDS             complement(7134..8135)
                     /locus_tag="ACL8CG_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGS1344066.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(8166..8807)
                     /locus_tag="ACL8CG_001494"
     CDS             complement(8166..8807)
                     /locus_tag="ACL8CG_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGS1344067.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFDRLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(8826..9641)
                     /locus_tag="ACL8CG_001495"
     CDS             complement(8826..9641)
                     /locus_tag="ACL8CG_001495"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGS1344068.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            9913..10341
                     /locus_tag="ACL8CG_001496"
     CDS             9913..10341
                     /locus_tag="ACL8CG_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIA"
                     /protein_id="HGS1344069.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFELGI"
     gene            10353..11543
                     /locus_tag="ACL8CG_001497"
     CDS             10353..11543
                     /locus_tag="ACL8CG_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGS1344070.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            11554..12045
                     /locus_tag="ACL8CG_001498"
     CDS             11554..12045
                     /locus_tag="ACL8CG_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1344071.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            12060..12839
                     /locus_tag="ACL8CG_001499"
     CDS             12060..12839
                     /locus_tag="ACL8CG_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1344072.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            12826..13644
                     /locus_tag="ACL8CG_001500"
     CDS             12826..13644
                     /locus_tag="ACL8CG_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1344073.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEVFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVAGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            13644..13937
                     /gene="yajC"
                     /locus_tag="ACL8CG_001501"
     CDS             13644..13937
                     /gene="yajC"
                     /locus_tag="ACL8CG_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS1344074.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            13959..15860
                     /locus_tag="ACL8CG_001502"
     CDS             13959..15860
                     /locus_tag="ACL8CG_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGS1344075.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRILAFGDSDSTETTEILSLFAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            15920..16921
                     /locus_tag="ACL8CG_001503"
     CDS             15920..16921
                     /locus_tag="ACL8CG_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1344076.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(17031..17366)
                     /locus_tag="ACL8CG_001504"
     CDS             complement(17031..17366)
                     /locus_tag="ACL8CG_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344077.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(17377..17619)
                     /locus_tag="ACL8CG_001505"
     CDS             complement(17377..17619)
                     /locus_tag="ACL8CG_001505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344078.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(17630..18172)
                     /locus_tag="ACL8CG_001506"
     CDS             complement(17630..18172)
                     /locus_tag="ACL8CG_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HGS1344079.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(18188..18382)
                     /locus_tag="ACL8CG_001507"
     CDS             complement(18188..18382)
                     /locus_tag="ACL8CG_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1344080.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEDDF"
     gene            18548..19498
                     /gene="rsmH"
                     /locus_tag="ACL8CG_001508"
     CDS             18548..19498
                     /gene="rsmH"
                     /locus_tag="ACL8CG_001508"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGS1344081.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            19510..19827
                     /gene="ftsL"
                     /locus_tag="ACL8CG_001509"
     CDS             19510..19827
                     /gene="ftsL"
                     /locus_tag="ACL8CG_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGS1344082.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            19831..22083
                     /gene="pbp2X"
                     /locus_tag="ACL8CG_001510"
                     /gene_synonym="pbpX"
     CDS             19831..22083
                     /gene="pbp2X"
                     /locus_tag="ACL8CG_001510"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGS1344083.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            22085..23065
                     /gene="mraY"
                     /locus_tag="ACL8CG_001511"
     CDS             22085..23065
                     /gene="mraY"
                     /locus_tag="ACL8CG_001511"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGS1344084.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            23674..25779
                     /locus_tag="ACL8CG_001512"
                     /pseudo
     CDS             23674..25779
                     /locus_tag="ACL8CG_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
BASE COUNT         8101 a         4670 c         5855 g         7663 t
ORIGIN      
        1 atttcataat aaaaacaccc caaaagttag attttttctg tctaactttt ggggtcagta
       61 cactttggct tttaaaccat tatcactatc aagatagttg taaaaatgca gaaggtggtt
      121 tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt ttttcagggg
      181 atactattat tagttggaat tccttaagat ttcaacccta ttttacagcg acagcatcta
      241 atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg gattatgacg
      301 aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact cgattacata
      361 gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca acatctaaga
      421 ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat accatgaatg
      481 taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc tatccagaga
      541 ataatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg atggtggctc
      601 ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta tggttccctg
      661 aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg aagttaagtg
      721 tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc attcccttgg
      781 ttggttctga gataggtatg ggtgttgatt tacctgaagt tgtagattgg tatgtattcc
      841 cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga tataaaacaa
      901 gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga gattctagta
      961 tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg tctataattg
     1021 aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa aggacatctt
     1081 taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa ttaaaagata
     1141 gattgttaaa tcaattcatc aatgcgaaaa actctcatga cttaatgaat atcttgcatc
     1201 atcaggataa ggaattgaga gggagtttgt tggaaatgat atttactagc caaaactaat
     1261 tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg tattcgttat
     1321 cactggtcac attgaaaatg tgaaataagc acctacaaca tagactttac aacacttcat
     1381 gtttcatatc atggggtgtt tttctattta agtcaaagcc catcaaaaaa tctcactatt
     1441 catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga gtttgtatcg
     1501 cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact tgcccatctc
     1561 gaccgatgag aaacttagag aaattccatt cgattcgttt tcctagtggg ccagatttct
     1621 ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta atcttggcaa
     1681 aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc tctgcgctgc
     1741 cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag ccctgatctt
     1801 gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca catccagtag
     1861 cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt gcttggttat
     1921 tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt ctttttctac
     1981 attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg aagaataagc
     2041 cctcaatatg atagaaaccg tttacaaata actttaaaaa tggtatgatt taattaaacc
     2101 ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga ttttacaata
     2161 tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga gtttgtcttc
     2221 acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg aagaaacgac
     2281 tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg atacaaaaaa
     2341 tttagttgaa aatggtgatt ttagtcagac ggaggacgga agcagtccgt ggacagggag
     2401 caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag atgcctcaac
     2461 tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga aattaagggc
     2521 agtggttcac cgtatggttc ctattgaagc taagaaaaag tataaactgc gtttcaagat
     2581 taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa gtggtaagga
     2641 caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga ccattgaagc
     2701 agactatagc ccgactttag atgttgataa aatcaagctg gagttattct atgaaacagg
     2761 aactgggact gtttccttta aggatattga gctggtagag gtagcagacc agctttctga
     2821 ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg gaaaaaaaca
     2881 tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg cttcagtcaa
     2941 aaatggaatt ttagaacctc ttaaggaagg gacaaccaat gtcattgtca gtaaagatgg
     3001 caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggatg catacacaga
     3061 ccgtttggat gactggaatg gcatcatcgc tgggaatcaa tactatgatt ctaaaaatga
     3121 acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc tatctagtat
     3181 ttcaagttag gcggaccgca cctatttgtg ggaaaaattt tcaaattata aaatgtctgc
     3241 aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga ccaatccttc
     3301 ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca tggaatggat
     3361 gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg attatgaaat
     3421 cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact tctctgatga
     3481 ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg aacatttccg
     3541 aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata tgggaagagt
     3601 aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta ccattcgctc
     3661 gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag atggatccta
     3721 tatcgaccat accaatgttg cctatacggg tgcttatggg aatgttttga ttgatggcct
     3781 gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag ataaaatgca
     3841 aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg gagagctgat
     3901 ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg tggccgcagt
     3961 agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa ccaaacaacg
     4021 tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg tctttaagaa
     4081 tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg caggagtcgc
     4141 aagtgttcca agaacaagtt acctatctgc ctttaacaag atggataaaa cagccatgta
     4201 caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta ccttgaatta
     4261 cgaacacatg aacaaggaaa ataaacatgg ttggtatacg agtgatggga tgttctatct
     4321 ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta atccatataa
     4381 gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag gtaaagttct
     4441 accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag caaccatgga
     4501 tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc tgaaggataa
     4561 gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg caactacaat
     4621 tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg ataaagaagc
     4681 ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt tagaatcgtc
     4741 cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca gtatgagtaa
     4801 ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca aggaagttga
     4861 aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt atggctatat
     4921 gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaagagt tagaaagtag
     4981 cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag gagtttgggg
     5041 cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag ttttgaaacg
     5101 tggagtctat accattcgaa aagaagggga tgaatataag attgcctact ataatcctga
     5161 aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag cagctcagcc
     5221 acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc attcggatca
     5281 aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag ggttcttgct
     5341 acttggggcg ttttatttat tccgtagagg aaagaacaac taatttgttc atcatctaga
     5401 tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat atcttcggat
     5461 ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg tgactatagc
     5521 gttttgaaac tagaatagga cgtcataact gctaaaagat ttctataaat tcatttgatt
     5581 ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt ctcgctccgt
     5641 gaggtgcgcg tcgaaggtta taccaaaaaa actccaaacg cgatacaata aaggtgttca
     5701 atccaattgt aaagcgaaag gagaaaaaat atggcacaaa aggctcatag tttatctcac
     5761 acaaagtgga ggtgttctat cacattgtgt tcacccctaa gtatagacga aaagtcatct
     5821 ataatcaata tagaagtagt ttaggcgaaa tatttcatcg cttgtgtagt tataaaggtg
     5881 ttgaaatgat cgagggtcac ttaatgccag accatgtaca catgttagtc agtattccgt
     5941 cgaggctaag tgtttcaagt tttatggggt atttaaaagg caaaagtgca ctcatgatgt
     6001 ttgacaaaca cgccaatctc aagtacaagt ttgggaatcg gcatttctgg gcggaaggtt
     6061 attatgtaag tccagtaggg cttaatgaag ccacaattaa gaaatatagt caagattaaa
     6121 gaaattatcg agtggatgat ttcttcacga gtatgaaaat ttgagaacga gtaaagcatg
     6181 atatatagta aaatgaaata agaacaggac aaaatcgatc aggacagtca aatcgatttc
     6241 taacaatgtt ttagaagcag aggtgtacta ttccagtttc aatctactat aacactagat
     6301 aaattgagtg taaaagaata tgaggatccc tttagggata gtggtaagta ataccaaagt
     6361 ctcttaaaga ggcaagtgac gagtcaagag caataaggct tgaacaacgt gaaagccagc
     6421 gtctttaggc gctggctgat gatttgggct tatagctctg agataaacca cccgttagac
     6481 gggtagttat gattttatct gagtgtaata tactgttggg caatctcgct gatgcggtca
     6541 aagttgcctt gggaagcgag tttattgagt tcgccaccaa ttccaacggc atctgcacca
     6601 gcagcgaacc attgagggat gttgtttagg ccgactcctc cggttaccat tacggaaact
     6661 tgtgggatcg gtgccttgac tgcagagata tatgctggac tgagagtact acctgggaag
     6721 agtttgatga tttcactacc ggcttcaagt gcagtcgtga tctctgtgag ggtaatacag
     6781 cctggaatgt acggtgtgct gtagagattg cacattttcg cagtttcagc atggaaagat
     6841 ggagaaacaa cgtaatttgc tccagctaga atggcatctc tagcagttac ggcatcaagc
     6901 acagtacctg caccgataca aacactctga tcgtcctgat acaagtctac aagttccttg
     6961 atgatttgtc ctgcatactg attggtatag gcgatttcaa tagctttgat accgcccttg
     7021 atacaagcaa tcgaggcttg tagtccttct tcctttgtat ttcctcgaat gacagcgaca
     7081 attttctgtt tttttagttc aataatcgta tctgatttgg tcatgtaatt ctcctaacga
     7141 atgatatctt gtgcatttgc cagtaaattt tcaatactag ttgcggaagt ggagagatgg
     7201 tctcctggaa gagtgcattt gagagttgcg ctcgcaactg caaagtcaat ggtagttttt
     7261 agggaggaat gatggagtag ttggtaaagg gcaccagata taaaggcatc cccgctacca
     7321 attcgttgat agactgcagt ttttagttgg acagactctt caaatcgttc ttccagagca
     7381 taggcttgat agacattttt gtcttgctca tcactagagc ggagggtatg gaaaatggcc
     7441 ttgaaaccat aggcttcttt taaaagtcgc atgcgatttt ccacctcttc taggctagca
     7501 ctgtctcttg gaaacatctc tagattttgg tcatcaatca tgagaggatc aataccgaag
     7561 caatagtcag taaaacgtgc aaacttagaa aattcatact tggcttctag gactgaaatc
     7621 atctttgttc tcagattgag atccattgaa acgacaattc ctcggcgctt ggcttcttcc
     7681 aagagtagga gaaggatcgc acggacctct tgaccgatag ctacggtgat tccactaaaa
     7741 tgaaaatggc taatcccctg aaagagagaa tccatatcta gcatgtttgg ccgaatctgg
     7801 ctgatactcg tatgcttacg atcgtagaaa acttcacttt gacgacaacc aaagccgttc
     7861 tccaaatagt agaggccgat tcgatcgcca agccgacaga ttgaactggt atcgatttgg
     7921 tgctgtttca agaatgtgag aaaacgatct ccaatctcgt tggcagggag tgcggtaaag
     7981 actttcgttg agatacccag ggcttgcaaa ttacaagcga tgttaatttc tgatccgcca
     8041 aaataagtcg aactggcaac atgatcgccg atactggtgg catctaatgg tgagattcga
     8101 attaatggtt cgccaaacag taatattttc gtcatccatt agttcctttc tggtttagaa
     8161 tagctttact tggctaatac ttctttcaaa taagcagcga cttcatcatc ttggcagttt
     8221 tcaaagaagt attcttggaa atatttgcca gagatggtgt ctttgaggaa gtcttggtcg
     8281 attgttttaa ggatggtcat caaatcattg tgggtgattt gtttcacctc gtttaagata
     8341 cgagcgttgc gttgttcagg gattacacgt tctcttgggt agccaccgcc catttcttca
     8401 gcaaataagc gatcaaacat caatttgagg gtcagttctg ccccccagcc aaatcctttg
     8461 gcataaggga tagacaaggc gttaccacca ttgatttgag aataaaggta agcgtcagtt
     8521 gggtccactg ctagaccaca gacaacacca gggaagctgt ttaaagcaag catagcccct
     8581 acacccgtac cacagccggt aacaacaaag tcaactgcct ttgtatttaa aaggatggca
     8641 gccattagtc cgttctgcac ataagttaat tgactttctc cttcttctcc acgcatacca
     8701 tagttaaata attggtagtc ttttttatct gtcgcttctt ttagactatc gtaaataatg
     8761 tgattcttgc tagcttgact attttcattg attaatgcga ttttcataag atcttctttc
     8821 tatttttact caggttgttt tccgatgtag gctaagatac cgccatctac atataggatg
     8881 tggccgttga caaaattgct ggcatcacta gcgagaaaga cagcagggcc catcaaatct
     8941 tcaggatttc cccaacgtgc agcaggtgtt tttgcaatga tgaactggtc aaatgggtgg
     9001 cgagaaccat cttcttgcaa ctcacgaaga ggtgctgttt gaggagtggc aatataaccc
     9061 ggtccaattc cgttacattg gatattggct ccaccgtatt cagacgcaat gttgcgggtc
     9121 aacattttca agcccccttt agcagcagca taagcgctaa ctgtttcacg tcccagttcg
     9181 ctcatcatcg aacaaatatt gataattttt ccatgccctt tctttatcat agaaggaata
     9241 actgcctttg aaacgataaa tggtgcgttt aagtcaatat cgatgacctt acggaaatca
     9301 gcggcgctca tttcgcacat tggaactcgg cggataatac cagcgttatt aacgaggatg
     9361 tcaatgacac caacctcttg ttcgatttgc ttgaccatgg cttggatacc gtcctcgtct
     9421 gtcacgtcac agacatatcc atgggcttcg atgccaactt cacgataagc ttcaatccct
     9481 ttattgacca gatcttgatt gatatcgtta aagacaatag tagcgccggc ttcagcgtag
     9541 gatttggcaa tagcaaatcc aattccataa gaagcgccgg tgatgagagc aatttttcct
     9601 tttaaagaaa actgctcaat tgagaatgat gtatttgtca tttgatactt cctttcaaat
     9661 ttgttaagac ttctctataa tcaaattata ttctagtaaa ccggttttgt caataaataa
     9721 atatttttat ttataaaaag gtttgttttc ctaaaaaaac ggaagatttt gaaatttctg
     9781 cctattaaaa tggttaaaaa gataatgaaa gcgctaatat ttttttaaaa aaactattga
     9841 caagataaaa ataaaggatt acaatgggga atataaagta aaccggtaaa cctaaacaag
     9901 aaaggagaaa agatgaaaat tgtacttgta gggcatggac attttgctac agggatttat
     9961 agttctttac aattgattgc aggtaatcaa gaaaatgtgg aggcgattga ctttgtggaa
    10021 ggaatgtcag cagatgaact caagcaaaaa atcttacttg caatttcaaa tgaagaagaa
    10081 gttttaatcc taagtgatct cttgggagga tcgccattca aggtttcttc taccataatg
    10141 ggagaaaatc cagtcaaaac aatgaatgtt ctctcgggtt tgaacttagc catgttaatg
    10201 gaagcagtct ttgctagaat ggctcatagc tttgatgagg ttgttaataa atcagtagtg
    10261 gcggcccagg gcggagtcgt aaatggtaaa gaattgtttt caacggatgc agaggaagaa
    10321 gatttcgaat tgggtattta aagggtaaaa gaatgataaa aaaggttacg attgaaaaaa
    10381 taaaatcgcc tgagcgcttc ttagaagtac cacttctgac gaaagaagaa gtcggccagg
    10441 caatcgataa ggttattcgg cagttagaac tcaaccttga ctatttcaag gaagatttcc
    10501 cgactccagc tacctttgat aatgtctatc caatcatgga taacacggaa tggaccaatg
    10561 gtttctggac aggagaactg tggttggctt atgaatacag tcaacaggat gcatttaaaa
    10621 acatcgctca taaaaatgtt ctttctttcc tggatcgtgt caataagaga gtagaattgg
    10681 atcaccatga tctcggcttc ttgtacacac cgtcttgtat ggctgaatat aagataaatg
    10741 gagatggaga ggctagagaa gcaaccttga aagctgcaga taagttgatt gaacgctatc
    10801 aagaaaaagg tggttttatt caagcttggg gagacttggg caagaaagag cattaccgtt
    10861 tgattatcga ctgcttgctc aatatccaac tcttattctt tgcttatcaa gaaacaggcg
    10921 atcaaaaata ctacgatatt gcagaaagcc atttctatgc ttcagctaat aatgtaatcc
    10981 gtgatgacgc ttcgtccttc cacaccttct attttgatcc tgagacaggt caacccttta
    11041 aaggtgtaac gagacaaggg tatagtgatg attcatgctg ggcacgtggt caatcatggg
    11101 gagtctatgg tattcctttg acttatcgtc acttaaaaga cgagtcctgc tttgacttgt
    11161 ttaagggtgt gaccaattat ttcttgaatc gtctgccaaa agatcatgtg tcctattggg
    11221 atttgatttt taatgatggt agtgatcaat cacgagattc ttcagcaaca gctatcgccg
    11281 tctgtgggat tcatgaaatg ctaaaacatc tcccagaggt ggatgctgac aaagatattt
    11341 ataaacatgc tatgcatgcc atgcttcgtt ccttgatcga acattatgca aatgatcaat
    11401 ttacccctgg tgggacaagt ctcctccacg gtgtgtactc atggcattca ggtaaaggag
    11461 tggatgaagg caatatctgg ggtgactact attatctaga agcccttatc cgtttctaca
    11521 aagactggaa cctatattgg taggaggaga aatatgacaa tgccaaatat tattatgacc
    11581 cgtatcgatg aacggttgat tcatggacaa ggacaacttt gggtaaaata cctaggttgt
    11641 aatacggtca ttgttgccaa tgacgaagta agcacggaca agatgcaaca aactctgatg
    11701 aaaacagttg tgccagactc agttgccatg cgtttcttcc ctttgcaaaa ggtgattgat
    11761 atcattcaca aggctaatcc tgctcaaacg atctttatcg ttgtaaagaa tgtgaaggat
    11821 gctttaacct tggtagaagg tggtgtccct atcaaagaaa tcaatattgg gaacattcac
    11881 aatgctactg gtaaagagca agtgacacgc tccatcttcc tgggtgaaga ggacaaggtg
    11941 gccctcaagg aattgagcca aactcatcaa gtaacattta atacgaaaac aactccaaca
    12001 ggaaatgatg gagctgttca agtcaacatt atggactata tttaaaagag gagatcgtta
    12061 tgtcgattaa tgtatttcaa gcgattttaa ttggattatg gacagctttc tgttttagtg
    12121 gaatgctgtt aggaatttac accaatagat gtattgttct gtcatttggt gtcggaatta
    12181 ttctaggtga tctgcctact gctcttgcaa tgggagctat tggtgaattg gcttatatgg
    12241 gattcggtgt tggtgctgga ggtactgttc caccaaaccc aatcggacct ggtatctttg
    12301 gtaccttgat ggctatcact agtgctggta aagtcagtcc agaagcggct cttgccctct
    12361 ctactccgat tgctgtggcg attcaattct tacaaacttt cgcctacact gtacgtgctg
    12421 gtgcgcctga aacggcgatg aagcacttga aaaaccataa tttgaagaaa ttcaagttca
    12481 ctctaaatgc aacaatttgg ttgtttgcct ttattggatt taccttgggt tgcttgggtg
    12541 ccctttcaat ggataccttg ttgaaactcg tagactacat tccaccggta ttacttacag
    12601 gtttgacagt tgctggtaaa atgctcccag ctatcggttt tgcgatgatc ttgtcagtga
    12661 tggctaagaa agagttgatt ccctttgtct tgttgggata tgtttgtgca gcttatctaa
    12721 acatcccaac aattggtatt gcaattgtag gtactatctt tgctttgatt gaattttata
    12781 acaagccaaa aacagcggat catgtggtag aggaggaagc acacgatgac tggatctaac
    12841 aaattaacaa aacgtgatta tcttaaaacg tctttgcggg cattcttttg tcaaaatgga
    12901 tttaactata gtaactatca agggttggga tatgccaatg tgatgtatcc tgctttgaaa
    12961 aaacactatg gagaggatca ggaagttttc taccaagcct tggaagaaaa ctgtgaattc
    13021 tataatacca acccacactt cctgcctttt attaccagct tgcatcttgt aatgttggaa
    13081 aatggccgtc cggcaaaaga aacacgtagc atcaagatgg ccttgatggg accattggca
    13141 ggtattgggg attctctttc tcaattctgt ttagctccat tgttctcaac catcgcagct
    13201 tcgtttgctc aagaaggctt ggttgccggt ccaatcttgt tcttccttgc gatgaatacg
    13261 attttaacag cgattaaatt gtcaactggt ctgtatggat acaaactagg aacaactgtg
    13321 attgataaac taagcgaaca gatggcaacg atttctcgta ttgccaatat tatcggtgta
    13381 accgtaattg ctggtttggc agcgacatct gttaagatta tggtgccgat tacctttgct
    13441 gcaggggaag ttaaagcaga cgctaaacaa agtatcgtaa gtattcaggg aatgcttgat
    13501 aaggttgctc cagctcttct accagcccta tttacacttt tagtttacta cttgatcaaa
    13561 gaaaagaaat ggacaacata taaactcgtt attttaacag ttatcatcgg aattatcgga
    13621 agctggctta agattatagc ttaatggata caacattgtt ttatggaata gtgattgtct
    13681 tggcagtgag tcccctttta ctgtcaagct ttcattctat tcgtcagcaa aagttgcttc
    13741 gcaaacagat ggagcaacga caagagtatt tagcttcttt aacatctggt gatgaagtgt
    13801 tgttattgtc tggaattcat ggaaaaatca tttctatcaa agatgacttg gtctccttgc
    13861 agattgcaaa aggtgtggtc atctatgtag aaaaggaaag tgtaatggga aagacaaaag
    13921 aactgctttt taagtagttc tttttctggt aatagataat gaaagaagaa agaagacaat
    13981 tttttgaaag aatcgatgga aaccaatgtc gtgattatat cttgtcccac tgttcaaaag
    14041 actatgagaa agtcaagcgt tcccttgaac gcttgatgga caatcgtttt atgtttgata
    14101 gtccttggga tatggagcct tgttcaaaaa tccatcaaat ccagccgatg gtatgggatc
    14161 aagtatttga agatgatcca gaatgggctt atatgctcaa tcgacaagaa tatctcttgc
    14221 agtttatgat agggtatctg gtagaaggag ataaggacta tattcaaaag tgcaagttct
    14281 ttctatttga ttggattgag caggtgagag aattttctcc tcaatccttg atgactagaa
    14341 ccttggatac gggtattcgt tcctttactt ggttgaaact actcttgctc ctcttgaaat
    14401 ttgacttgct agaggagaaa gaactagaga aaattttggt cagtctagaa aagcagattg
    14461 actttatgaa aagccactat cgcgccaagt acacccttag taactggggg attttacaaa
    14521 caattccgat gcttgctatc tattatttct tttcagataa gatggaccta gaagaagctt
    14581 accattttgc ttcagaggag ttgaaacagc aaattgagac acagatttta ggagatggaa
    14641 gccagtttga acagtcgatt ctctatcatg tagaggttta taaagccttg ctggatttgt
    14701 gtctcttgct tccagacttg caagatagtt accaagagtt gctggaaaag atggcgacct
    14761 atattcaaat gatgacaggc ttagatggac ggattttggc ttttggtgat agcgattcta
    14821 cagaaacgac agaaattttg agcctgtttg ctgtggtttt gaacaaggaa gaccttctta
    14881 acggtctgga tgttaaagtc gatttgctta gcctcttgtt cctggggcga gaaaaggtca
    14941 agcgactgca ggaatttgaa aggagagctt ggcagcctag gtccatgatc tttgaagact
    15001 ctggacatgt ctgcattaag gatgaacatc gttatctatt tttcaaaaat ggtccgctag
    15061 gaagtgccca tagccatagt gacgagaata gtttttgctt acagtatcaa ggccaaccta
    15121 ttttcataga tgctgggcgt tattcttatc gggagatata tgaacgttat ctcttaaaga
    15181 gtgcttggag tcattcgacc tgcattgtag atgggaaagc tccggaaaga atcacgggat
    15241 cctgggaata tgaatactat cctcactccc tgttttgtca ccataaagaa agggagggag
    15301 tgcattatat tgaaggggct tattggtcag cagaacctga tttgccttat cttcacaaga
    15361 gaaaaatcct catgttggta gaggatgtct ggctcttggt agatgacatc aggtgtcaag
    15421 gtcagcatga ggcgttgact cagtttatcc ttgacaagga tgtgacctat caagatggga
    15481 aaatcaatca gttgagacta tggagtgaag ttgattttga tttggaagat accatcattt
    15541 ctcctaaata caatgagctt gaaagaagta gcaaactcac caagcgccaa ttctttgaga
    15601 atcagatgct ggattatacc atcattgcgc atgagagttt tgaaatcatc cgtcattctg
    15661 tctaccagac agatgatcgt gaagtggaaa atgctctggc ttttgaagtg aaaaatgacg
    15721 aaacagacaa gctgattctg ttattaagcg aggatattgg tgtaggtgaa aaattgtgcc
    15781 tcgttgacgg aacaaaaatg cgtggaaaat gtctagtata tgataaaata aatgagagaa
    15841 tgattcgctt gcagtgctag aaataggcat tttgaatagt gaacatgtta taataagtat
    15901 tagtaggagg tgttttagat tggagaagaa actgaccata aaagacattg cggaaatggc
    15961 tcagacctcg aaaacaaccg tgtcatttta cctaaacggg aaatatgaaa aaatgtccca
    16021 agagacacgt gaaaagattg aaaaagttat tcatgaaaca aattacaaac cgagcattgt
    16081 tgcgcgtagc ttaaactcca aacgaacaaa attaatcggt gttttgatcg gtgatattac
    16141 caacagtttc tcaaaccaaa ttgttaaggg aattgaggat atcgccagcc agaatggcta
    16201 ccaggtaatg ataggaaata gtaattacag ccaagagagt gaggaccggt atattgaaag
    16261 catgcttctc ttgggagtag acggctttat tattcagccg acctctaatt tccgaaaata
    16321 ttctcgtatc atcgatgaga aaaagaagaa aatggtcttt tttgatagtc agctctatga
    16381 acaccggact agctgggtta aaaccaataa ctatgatgcc gtttatgaca tgacccagtc
    16441 ctgtatcgaa aaaggttatg aacattttct cttgattaca gcggatacga gtcgtttgag
    16501 tactcggatt gagcgggcaa gtggttttgt ggatgcttta acagatgcta atatgcgtca
    16561 cgccagtcta accattgaag ataagcatac gaatttggaa caaattaagg aatttttaca
    16621 aaaagaaatc gatcccgatg aaaaaactct ggtatttatc cctaactgtt gggccctacc
    16681 tctagtcttt accgttatca aagagttgaa ttataacttg ccacaagttg ggttgattgg
    16741 ttttgacaat acggagtgga cttgcttttc ttctccaagt gtttcgacgc tggttcagcc
    16801 ctcctttgag gaaggacaac aggctacaaa gattttgatt gaccagattg aaggccgcaa
    16861 tcaagaagaa aggcaacaag tcttggattg tagtgtgaat tggaaagagt cgactttcta
    16921 aaatgaagga aaatgacttg caatctctgt taagaaataa aataatccca cctagaacaa
    16981 gctaggtggg attatttgcc tatgaaatga gaaattatgg gagcaagctc ctaaatcaac
    17041 tgtttttgat ctacttcttt aactacttga taaaagttat agaagtaggc caaacttgaa
    17101 atgatggtta cgactaggaa tattgaaaat ttccattgga cagggttggt taaaagttgt
    17161 ggaaaggata tgaggagaaa gaagagggct gcgttgagga caggtatccg ttttgattgt
    17221 attttctcaa gtcctttatt gagcgcagga agaaagagga gtaggagtag taaaactgta
    17281 tgagaaacag ctcctgaaat aagggcaaag aaaaggaaaa tactgataaa aacatgaatg
    17341 atcagtagtc tagctagtga tttcataagg tacctcctaa tcctggtctt ttttagctct
    17401 tgcaatacga agtgagtcga caatatgtat catcactccg aaaaagaaag ctcccagtat
    17461 agttttaaaa atatgttttg tatttagaag agaactgata aaatttggat tttcacttgt
    17521 tagggtatca atgagtggaa ttataaaaaa tatcactgtt ccataaatcg aacctgcttt
    17581 cagaccagga taacgtaact gtctcttttc ttttttcata gggcacctcc taatcctcat
    17641 cttgattttt cttagttttt gcaatgcgac gggagatgag gaactgtatg ctcgctccga
    17701 agaaaataga accgagaatg cttgatacac catttcttat agtgagaaga gaatgaaaat
    17761 agtcctgacc ttcacctatg agtatcctga gaagaggagt tataaaaaac atccatagac
    17821 caaagaacaa acctgctttc agacctgggt aatgtagttg cttactttct ttctcgctca
    17881 gcatgtctgg atcaatagct gtaatccctg tttttttcat ttggtaggtg acatagccag
    17941 cagcgatgag ggcaatcact aaaatcagag gaggatagat tagagccact tcttgagggt
    18001 atttataggc cagaaggagt ggaataagat ttccgaaaat catcagataa aagaggatga
    18061 taaagacttg gttcccaata cgatcggcct cacgccgttt gtattcgtca aggggaccag
    18121 aaataccgta tgtgcgtttg atcagttttt cagtgaaggt ttcttttttc atgagtttgc
    18181 tcctttttta aaaatcatcc tcccaaaaga gactgttgag gtcagtttgg aggctgcggg
    18241 cgagattgag acagagttcc aaggttggat tgtacttgtc gttttcaatc atattgatag
    18301 tctgtctcga gacaccgata tccttggcga gctcgagctg ggaaatgccc agttccttgc
    18361 gaaattcttt cacacgattc atctggtctc ctttctgatt tgtgtcgtat atatttgact
    18421 ttattatagt cttttaaaca taaagtgtca agtatttttg acatattttt tgaagaaata
    18481 gtagtctcct tgtcctattt gtctgacaag tgcaagctgg tcggatttgt ggtaaaatag
    18541 ataagatatg acaaaagaat ttcatcatgt aacggtctta ctccacgaaa cgattgatat
    18601 gcttgacgta aaacctgacg gtatctacgt tgatgcgact ttgggtggag caggccatag
    18661 cgagtattta ttaagtaaat taagtgaaaa aggccatctc tatgcctttg accaggatca
    18721 gaatgccatt gacaatgcgc aaaaacgctt ggcaccttac attgagaagg gaatggtgac
    18781 ctttatcaag gacaacttcc gtcatttaca ggcacgtttg cgcgaagctg gtgttcagga
    18841 aattgatgga atttgttatg acttgggagt gtctagtcct caattagacc agcgtgagcg
    18901 tggtttttct tataaaaagg atgcgccact ggacatgcgg atgaatcagg atgctagcct
    18961 gacagcctat gaagtggtga acaattatga ctatcatgac ttggttcgta ttttcttcaa
    19021 gtatggagag gacaaattct ctaaacagat tgcgcgtaag attgagcaag cgcgtgaagt
    19081 gaagccgatt gagacaacga ctgagttagc agagattatc aagttggtca aacctgccaa
    19141 ggaactcaag aagaaggggc atcctgctaa gcagattttc caggctattc gaattgaagt
    19201 caatgatgaa ctgggggcgg cagatgagtc catccagcag gctatggata tgttggctct
    19261 ggatggtaga atttcagtga ttacctttca ttccttagaa gaccgcttga ctaagcaatt
    19321 gttcaaggaa gcttcaacag ttgaagttcc aaaaggcttg cctttcatcc cagatgatct
    19381 caagcccaag atggaattgg tgtcccgtaa gccaatcttg ccaagtgcgg aagagttaga
    19441 agccaataac cgctcgcact cagccaagtt gcgcgtggcc agaaaaattc acaagtaaga
    19501 gggaaaaaga tggcagaaaa aatggaaaaa acaggtcaaa tactacagat gcaacttaaa
    19561 cggttttcgc gtgtggaaaa agctttttac ttttccattg ctgtaaccac tcttattgta
    19621 gccattagta ttatttttat gcagaccaag ctcttgcaag tgcagaatga tttgacaaaa
    19681 atcaatgcgc agatagagga aaagaagacc gaattggacg atgccaagca agaggtcaat
    19741 gaactattac gtgcagaacg tttgaaagaa attgccaatt cacacgattt gcaattaaac
    19801 aatgaaaata ttagaatagc ggagtaagat atgaagtgga caaaaagagt aatccgttat
    19861 gcgaccaaaa atcggaaatc gccggctgaa aacagacgca gagttggaaa aagtctgagt
    19921 ttattatctg tctttgtttt tgccattttt ttagtcaatt ttgcggtcat tattgggaca
    19981 ggcactcgct ttggaacaga tttagcgaag gaagctaaga aggttcatca aaccacccgt
    20041 acagttcctg ccaaacgtgg gactatttat gaccgaaatg gagtcccgat tgctgaggat
    20101 gcaacctcct ataatgtcta tgcggtcatt gatgagaact ataagtcagc aacgggtaag
    20161 attctttacg tagaaaaaac acaatttaac aaggttgcag aggtctttca taagtatctg
    20221 gacatggaag aatcctatgt aagagagcaa ctctcgcaac ctaatctcaa gcaagtttcc
    20281 tttggagcaa agggaaatgg gattacctat gccaatatga tgtctatcaa aaaagaattg
    20341 gaagctgcag aggtcaaggg gattgatttt acaaccagtc ccaatcgtag ttacccaaac
    20401 ggacaatttg cttctagttt tatcggtcta gctcagctcc atgaaaatga agatggaagc
    20461 aagagcttgc tgggaacctc tggaatggag agttccttga acagtattct tgcagggaca
    20521 gacggcatta ttacctatga aaaggatcgt ctgggtaata ttgtacccgg aacagaacaa
    20581 gtttcccaac gaacgatgga cggtaaggat gtttatacaa ccatttccag ccccctccag
    20641 tcctttatgg aaacccagat ggatgctttt caagagaagg taaaaggaaa gtacatgaca
    20701 gcgactttgg tcagtgctaa aacaggggaa attctggcaa caacgcaacg accgaccttt
    20761 gatgcagata caaaagaagg cattacagag gactttgttt ggcgtgatat cctttaccaa
    20821 agtaactatg agccaggttc cactatgaaa gtgatgatgt tggctgctgc tattgataat
    20881 aatacctttc caggaggaga agtctttaat agtagtgagt taaaaattgc agatgccacg
    20941 attcgagatt gggacgttaa tgaaggattg actggtggca gaatgatgac tttttctcaa
    21001 ggttttgcac actcaagtaa cgttgggatg actctccttg agcaaaagat gggagatgct
    21061 acctggcttg attatcttaa tcgttttaaa tttggagttc cgacccgttt cggtttgacg
    21121 gatgagtatg ctggtcagct tcctgcggat aatattgtca acattgcgca aagctcattt
    21181 ggacaaggga tttcagtgac ccagacacaa atgattcgtg cctttacagc tattgctaat
    21241 gacggtgtca tgctggagcc taaatttatt agtgccattt atgatccaaa tgatcaaact
    21301 gctcggaaat ctcaaaaaga aattgtggga aatcctgttt ctaaagatgc agctagtcta
    21361 actcggacta acatggtttt ggtagggacg gatccggttt atggaaccat gtataaccac
    21421 agcacaggca agccaactgt aactgttcct gggcaaaatg tagccctcaa gtctggtacg
    21481 gctcagattg ctgacgagaa aaatggtggt tatttagtcg gggtaaccga ctatattttc
    21541 tcggctgtat cgatgagtcc ggctgaaaat cctgatttta tcttgtatgt gacggtccaa
    21601 caacctgaac attattcagg tattcagttg ggagaatttg ccaatcctat cttggagcgg
    21661 gcttcagcta tgaaagactc tctcaatctt caaacaacag ctaaagcttt ggagcaagta
    21721 agtcaacaaa gtccttatcc tatgcctagt gtcaaggata tttcacctgg tgatttagca
    21781 gaagaattgc gtcgcaatct tgtacaaccc atcgttgtgg gaacaggaac gaagattaaa
    21841 aacagttctg ctgaagaagg gaagaatctt gccccgaatc agcaagtcct tatcttatct
    21901 gataaagcag aggaggttcc agatatgtat ggttggacaa aggagactgc tgagaccctt
    21961 gctaagtggc tcaatataga acttgaattt caaggctcgg gctctactgt gcagaagcaa
    22021 gatgttcgtg ctaacacagc tatcaaggac attaaaaaaa ttacattaac tttaggagac
    22081 taatatgttt atttccatca gtgctggaat tgtgacattt ttactaactt tagtaggaat
    22141 tccggccttt atccaatttt atagaaaggc gcaaattaca ggccagcaga tgcatgagga
    22201 tgtcaaacag catcaggcaa aagctgggac tcctacaatg ggaggtttgg ttttcttgat
    22261 tacttctgtt ttggttgctt tctttttcgc cctatttagt agccaattca gcaataatat
    22321 gggaatgatt ttgttcatct tggtcttgta tggcttggtc ggatttttag atgactttct
    22381 caaggtcttt cgtaaaatca atgaggggct taatcctaag caaaaattag ctcttcagct
    22441 tctaggtgga gttatcttct atcttttcta tgagcgcggt ggcgatatgc tttctgtctt
    22501 tggttatcaa gtgcatctag ggattttcta tattgtcttc gctcttttct ggctagtcgg
    22561 tttttcaaac gcagtaaact tgacagacgg tgttgacggt ttagctagta tttccgttgt
    22621 gattagtttg tctgcctatg gagttattgc ctatgtgcaa ggtcagatgg atattcttct
    22681 agtgattctt gccatgattg gtggtttgct cagttttttc atctttaacc ataagcctgc
    22741 taaggtcttt atgggtgatg tgggaagttt ggccctaggt gggatgctgg cagctatctc
    22801 tatggctctc caccaagaat ggactctctt gattatcgga attgtatatg tttttgaaac
    22861 aacttctgtt atgatgcaag tcagttattt caaactgaca ggtggtaaac gtattttccg
    22921 tatgacgcct gtacatcacc attttgagct tgggggattg tctggtaaag gaaatccttg
    22981 gagcgagtgg aaggttgact tcttcttttg gggagttggg cttctagcaa gtctcctgac
    23041 ccttgcaatt ttgtatttga tgtaagaatg gcaccctgat gtttcagggt gtttttgtgt
    23101 ttaaatacac aatgaaaatc aaagaacaaa ctagaaagct aactttaggc tgctcaaaat
    23161 ataatagatt gaaactagaa tagtacacct ctacttctaa aacattttta gaaatcgatt
    23221 tgactgtcct gattgatttg tcctgttctt atttcatttt actatacagt tttgagatgg
    23281 ttgatagaac tgacgaagtc agctcaaaac actgttttga ggttgtagac aaggcgaagc
    23341 tgatgtggtt tgaagaggtt ttcgaagagt gtaaaaaaat attggtcagt taaagtcaaa
    23401 attcttgacc ttttctgacc aatgtagtat attatgaacg taaggtaaat gaaagcctta
    23461 ctagaacact tatttaaagt aaaatagaaa gaggtgagtc tatgtttcat ctagcaatct
    23521 tcagaggtaa agatagtcta ctcctgcttg aaaaagaaaa accagaaata gtacgtaggg
    23581 tagcggttta gctagtctaa attttttaaa acaatggtca aagatagtca atatcagtaa
    23641 tcataactaa gtaaacaaaa agaggtaaag aatatgaata acaactttaa taattttaat
    23701 aacatggatg atttatttaa ccaattgatg ggtggtatgc gaggatatag ttctgaaaat
    23761 cgccgttact taattaatgg acgcgaagtc acacctgagg aatttgctca ctatcgtgcg
    23821 actggtcaat taccaggaaa tgcagaaact gatgtgtaaa tgccacaaca ggcatcaggt
    23881 atgaaacaag acggtgtcct tgcaaaacta ggtcgaaact tgacagcaga agcgcgtgag
    23941 ggcaagttgg atcctgttat cggacgaaac aaggaaattc aagaaacatc tgaaatcctc
    24001 tcacgccgca ccaagaacaa tcctgttttg gtcggagatg caggtgttgg taagacagca
    24061 gttgtcgaag gtctagcgca agccattgtg aacggagatg ttcctgctgc tatcaagaac
    24121 aaggaaatta tttctattga tatctcaggt cttgaggctg gtactcaata ccgtggtagc
    24181 tttgaagaaa atgtccaaaa cttagtcaat gaagtgaaag aagcagggaa tattatcctc
    24241 ttctttgatg aaattcacca aattcttggt gctggtagca ctggtggaga cagtggttct
    24301 aaagggcttg cggatattct caagccagct ctctctcgtg gagaattgac agtgattggg
    24361 gcaacaactc aagacgaata ccgtaacacc atcttgaaga atgctgctct tgctcgtcgt
    24421 ttcaacgaag tgaaggtcaa tgctccttcg gcagagaata cttttaaaat tcttcaagga
    24481 attcgtgacc tctatcaaca acaccacaat gtcatcttgc cagacgaagt cttgaaagca
    24541 gcggtggatt attctgttca atacattcct caacgtagct tgccagataa ggctattgac
    24601 cttgtcgatg taacggctgc tcacttggcg gctcaacatc cagtaacaga tgtgcatgct
    24661 gttgaacgag aaatcgaaac ggaaaaagac aagcaagaaa aagcagttga agcagaagat
    24721 tttgaagcag ctctaaacta taaaacacgc attgcagaat tggaaaagaa aatcgaaaac
    24781 cacacagaag atatgaaagt gactgcaagt gtcaacgatg tggctgaatc tgtggaacga
    24841 atgacaggta tcccagtatc gcaaatggga gcttcagata tcgaacgttt gaaagatatg
    24901 gctcatcgct tgcaagacaa ggtgattggt caagataagg ccgtagaagc tgtagctcgt
    24961 gctatccgtc gtaaccgtgc tggttttgat gaaggaaatc gcccaatcgg cagcttcctc
    25021 tttgtagggt ctactgggat tggtaagacg gagcttgcta agcaattggc actcgatatg
    25081 tttggaaccc aggatgcgat tatccgtttg gatatgtctg aatacagtga ccgcacagct
    25141 gtttctaagc taattggtac aacagcaggc tatgtgggtt atgatgacaa tagcaatacc
    25201 ttaacagaac gtgttcgtcg caatccatac tctatcattc tcttggatga aattgaaaag
    25261 gctgatcctc aagttattac ccttctcctc caagttctag atgatggtcg tttgacagat
    25321 ggtcaaggaa atacagtaaa cttcaagaat actgtcgtta ttgcgacctc aaatgctgga
    25381 tttggctatg aagccaattt gacagaagat gcggataaac cagaattgat ggaccgtttg
    25441 aaacccttct tccgtccaga attcctcaac cgctttaatg cagtcatcga gttctcacac
    25501 ttgactaagg aagacctttc taagattgta gatttgatgt tgactgaagt taaccaaacc
    25561 ttggctaaga aagacattga cttggtagtc agtcaagcgg ctaaagatta tatcacagaa
    25621 gaaggttacg acgaagtcat gggggttcgt cctctccgtc gagtggttga acaagaaatt
    25681 cgtgataagg tgacagactt ccacttagat catttagatg ctaaacatct ggaagcagat
    25741 atggaagatg gcgttttggt tattcgtgag aaagcctaag acagaatttt taggataaaa
    25801 aagaaggagc cagctgaaaa aaactggttc cttttgaggt acgacgggca tgtcgtgtag
    25861 taggttgaaa ctagaatagt acacatctac ttctaaaaca ttgttagaaa tcgatttgac
    25921 tgtcctgaac gatttgtcct gttcttattt cattttacta tatatctgaa tatctgaggt
    25981 gtaagtcctc ggtgggcacc cactaccggt gaacccaata gcgattccca agcctgacta
    26041 tcgtgaggta gtggattaaa acggtctggg gatagaccgt tttaagtctg acgctggaaa
    26101 taagaatcgt cagaggaagg gatagcgaaa tcgtggcttt acgaacagga acgtgatagt
    26161 aaggcgtata tagcggataa gggggtctca aactctaaag ttcaaaaagg tagtcgtaac
    26221 ctatatgcgt aaatcacgag agcaactgaa tttgttcatt cgaggatgga taaactattt
    26281 ctcattggg
//
LOCUS       DBEROT010000032        24731 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.32, whole genome shotgun sequence.
ACCESSION   DBEROT010000032 DBEROT010000000
VERSION     DBEROT010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24731
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.32"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..657
                     /locus_tag="ACL8CG_001513"
                     /pseudo
     CDS             1..657
                     /locus_tag="ACL8CG_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(867..3125)
                     /locus_tag="ACL8CG_001514"
     CDS             complement(867..3125)
                     /locus_tag="ACL8CG_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1344085.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKVLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
     gene            complement(3354..3584)
                     /locus_tag="ACL8CG_001515"
     CDS             complement(3354..3584)
                     /locus_tag="ACL8CG_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGS1344086.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3774..4457
                     /locus_tag="ACL8CG_001516"
     CDS             3774..4457
                     /locus_tag="ACL8CG_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1344087.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4457..5191
                     /locus_tag="ACL8CG_001517"
     CDS             4457..5191
                     /locus_tag="ACL8CG_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1344088.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5345..6202
                     /locus_tag="ACL8CG_001518"
     CDS             5345..6202
                     /locus_tag="ACL8CG_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGS1344089.1"
                     /translation="MTQIIDGKALAVKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6344..7216
                     /locus_tag="ACL8CG_001519"
     CDS             6344..7216
                     /locus_tag="ACL8CG_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGS1344090.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7498..8181
                     /gene="rpiA"
                     /locus_tag="ACL8CG_001520"
     CDS             7498..8181
                     /gene="rpiA"
                     /locus_tag="ACL8CG_001520"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGS1344091.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            8195..9406
                     /locus_tag="ACL8CG_001521"
     CDS             8195..9406
                     /locus_tag="ACL8CG_001521"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGS1344092.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9408..9965
                     /locus_tag="ACL8CG_001522"
                     /pseudo
     CDS             9408..9965
                     /locus_tag="ACL8CG_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893195.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9965..10774
                     /locus_tag="ACL8CG_001523"
     CDS             9965..10774
                     /locus_tag="ACL8CG_001523"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS1344093.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            11250..11646
                     /locus_tag="ACL8CG_001524"
                     /pseudo
     CDS             11250..11646
                     /locus_tag="ACL8CG_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
     gene            11959..12234
                     /locus_tag="ACL8CG_001525"
     CDS             11959..12234
                     /locus_tag="ACL8CG_001525"
                     /inference="COORDINATES: protein motif:HMM:NF012956.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGS1344094.1"
                     /translation="MENIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQ
                     SKPWWQVDLAKEETIRQINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12259..12772
                     /locus_tag="ACL8CG_001526"
                     /pseudo
     CDS             12259..12772
                     /locus_tag="ACL8CG_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
     gene            13426..14136
                     /gene="deoD"
                     /locus_tag="ACL8CG_001527"
     CDS             13426..14136
                     /gene="deoD"
                     /locus_tag="ACL8CG_001527"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS1344095.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKFGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14159..14683)
                     /locus_tag="ACL8CG_001528"
     CDS             complement(14159..14683)
                     /locus_tag="ACL8CG_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGS1344096.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14736..14972)
                     /gene="rpsT"
                     /locus_tag="ACL8CG_001529"
     CDS             complement(14736..14972)
                     /gene="rpsT"
                     /locus_tag="ACL8CG_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGS1344097.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(15040..15960)
                     /gene="coaA"
                     /locus_tag="ACL8CG_001530"
     CDS             complement(15040..15960)
                     /gene="coaA"
                     /locus_tag="ACL8CG_001530"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGS1344098.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16158..16563
                     /locus_tag="ACL8CG_001531"
                     /pseudo
     CDS             16158..16563
                     /locus_tag="ACL8CG_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16770..17360
                     /locus_tag="ACL8CG_001532"
     CDS             16770..17360
                     /locus_tag="ACL8CG_001532"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1344099.1"
                     /translation="MSKMYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDF
                     GSQLLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEK
                     NNAKATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17357..18634
                     /locus_tag="ACL8CG_001533"
     CDS             17357..18634
                     /locus_tag="ACL8CG_001533"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGS1344100.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYCPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18652..19314
                     /gene="deoC"
                     /locus_tag="ACL8CG_001534"
     CDS             18652..19314
                     /gene="deoC"
                     /locus_tag="ACL8CG_001534"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGS1344101.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGSDFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            19301..19690
                     /locus_tag="ACL8CG_001535"
     CDS             19301..19690
                     /locus_tag="ACL8CG_001535"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS1344102.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19780..20832
                     /locus_tag="ACL8CG_001536"
     CDS             19780..20832
                     /locus_tag="ACL8CG_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGS1344103.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20976..22511
                     /locus_tag="ACL8CG_001537"
     CDS             20976..22511
                     /locus_tag="ACL8CG_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344104.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVVDISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            22504..23562
                     /locus_tag="ACL8CG_001538"
     CDS             22504..23562
                     /locus_tag="ACL8CG_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344105.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23565..24521
                     /locus_tag="ACL8CG_001539"
     CDS             23565..24521
                     /locus_tag="ACL8CG_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344106.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7251 a         4435 c         5578 g         7467 t
ORIGIN      
        1 atgggctaca ctcgaaaaaa agaaccacac ctactatgaa caagacccag aaaagtagcc
       61 ttatttctta agaattttaa tagtttaaag cacctagcac ctgtttagat tgatgaaaca
      121 ggattcgata cttattttta tcgagaatat ggtcgctcat taaaaggtca gttaagaaga
      181 ggcaaagtat ctggaagaag atatcagaga atttctttgg ttgcaggtct aacaaatggt
      241 gagttaatcg ctccaataac ttacgaagag acgatgacga gcgacttttt tgaagcttgg
      301 tttcagaaat ttctcttacc aacattaaac acaccatcgg ttattatagt aaaataaaat
      361 aagaatagga taaatcgatc aggacagtaa aatcgaattc taacaatgtt ttagaagtag
      421 atgtgtacta ttctagtttc aatctactat attatggata atgcaagatt ccatagaatg
      481 gggaagctag aacttttatg cggagagttt gggcataaac ttttacctct tcctccctac
      541 tcacctgagt acaatcctat tgagaaaaca tgggctcata tcaaaaagca cctcaaaaag
      601 gtattaccaa gttgcaatac cttttacgag gctcttttgt cctgttcttg tttcaattga
      661 ctgtagcaga ttgaaataag atgagaacaa atcgatttgg aaagtaaaat taatttctat
      721 aaatgtttta gcaattgttt cgtactattt cagattcagt ctactatata tcataatgga
      781 caaagggcaa gctgtcaaga aattacagtt attttagtaa aaaaagaagc agaaaaattt
      841 cattttctac tccttttcta taggatttat ttttcttttt cagaactttt aacttcagtt
      901 tttttggcag atttaatctg aatgtttccc ttgctagtca taactgcttt gagaactttt
      961 tcgcttggat tttcaaggta gtagtcagtg attgtgtcct caatatagtc ttgaatagtt
     1021 cgacgaagtg ggcgtgctcc catttttgga tcataaccta ggtcaaccaa cttttccttg
     1081 accttgtcag ttacatccaa acgaatgttg ttgctagaga ggcgcttgtt aacatctgct
     1141 agcatgagct cgacaatctg aaggaggtta tccttgctga gagccttaaa ttcgataatg
     1201 ccatcaaaac ggttcataaa ctctgggcta aagaagttac cgagttcacc gaggacagaa
     1261 ttggtacgtc cttctctagc agcaccaaat ccaacgctag cttcggtctt tcctgtacct
     1321 gcatttgagg tcatgataat gatggcatcc ttgaagctaa cggtgcgtcc ttgcccgtct
     1381 gtcaaacgac catcgtccaa gacttgaaga aacatgtgca taacatctgg gtgagctttt
     1441 tccacttcat cgagaaggat gagagaatat ggattgtggc gaactttttc agttaattga
     1501 ccagcctcat catagccaac ataacctgga ggagcgccga ccaacttagc cacactatgt
     1561 ttttccatgt attcactcat atcaaagcga atcatactat cagcagaacc aaaaagttcg
     1621 atagccagtt gtttggaaag ttctgtctta ccgacaccag ttggcccaac gaagaggaag
     1681 cttccgattg ggcggttagg ggtaccaagt ccgacacgat tacggcgaat agccttggca
     1741 atcttatcga ctgcatcatc ttgaccaata acatgagact tgagatcttc ggctagatgg
     1801 atgagttgag attgttcttt ctctttcaaa tcaccaacag ggatattggt tttctgctcg
     1861 ataatgtgct caatagtttt ctcgctgatg ataggagtat cctggtctgt gatctttttc
     1921 ttttgcattt ccttatactt ggcaatctgg tcgcggaagt aggccgcctt ctcaaaatct
     1981 tcttctcgtg tagcttgaga cttgagattt tcagcctcaa tcaagcgctg atcaattact
     2041 ttaggatcca caaaattcaa ggtcaagttc atcttagaac cagcttcatc taggaggtca
     2101 atggccttgt caggcaagaa gcgatcttgg atgtagcgat tggaaagagt tgcagctgct
     2161 tcaatcgcag catctgtata ttgaacgtgg tggtaatctt cgtatttctt ttgaatccct
     2221 ttgagaatag tgattgtttc gtccaccgtt ggttcatcga ctttaacagg ctgcatacga
     2281 cgctcgaggg cagcatcctt ttcaatgata cggtattcat tgagggtagt agcaccgact
     2341 agttgcagtt ctccacgagc aagggctggc ttgaggatat ttcctgcgtc catattacca
     2401 tcactcgcag aaccagcacc aacaatttca tggatttcat cgataaagag gatgatgtct
     2461 tcacgtttgc gaatttcttc catgagtttt tgcatgcgtt cttcaaattg tcctcgaatc
     2521 cccgttcctt gaactaagct aaccacatcc agacggatga cttgtttacc ttggagttta
     2581 tgtggcacat cgccatcgac aattttctga gctagacctt cgacaacggc cgtttttccg
     2641 acaccaggtt caccgataag gacaggatta ttcttggttc tacgattgag aatctcgatg
     2701 acacggataa tctcatcgtc gcgcccaata acggggtcaa tgtctccacg acgggcaatt
     2761 tcagttacat taataccaaa ttcttccagc aggccttttt cttggctagg tggcggagtt
     2821 tgagcagatc cacgattttg ggaaccataa ccgccgtttc caccgtaacc tccacctgat
     2881 tgggttgggg gaataggagg agtattgcta gaaggtctga aattgtttag atcattgaag
     2941 aaatcaccaa agggatcgaa gtcacgattg ttcagatccg tcataccttt gaagaggcta
     3001 ttgttaggat ctgttttgat aatcttatag cagttttgac agaggtcaat ttgtttttgt
     3061 tttccattga gattggtgta aagatgaatt gttgagtcgt taattttaca gttttgacaa
     3121 agcatacatc tacctcattt ctttctttag cctgacttgt ttaaaggtca aaaatagtca
     3181 aattctatac tctcattata acaggattgg ggtgtaaagc aagtaaaaag attgaagctt
     3241 tgagaagttg ttacaatgaa aatttttgtg aatttggact ataaaaaaat cctatttgtg
     3301 agacaaaaag gattttactt agacatgcag ggacaatccc agcttgtttt agattagtag
     3361 agaagttcgt aaatttccat tgcgattaag tcaatgctat caaacgtata cgtttcgcga
     3421 tcttctacgt cacgaagggt aaagattggg ccgttttctt cgtcgtggct gtacgcaact
     3481 tctgcaacaa caactccttc gcgttcaaaa ttacgtttta aatttccgcc atcgtttgcc
     3541 attgcttcaa ggcggttgat gattctaacc aaatgtgatt ccattttgat tctccttcat
     3601 ttcttatcgt tactatttta ccataaagga ggccaacttg actagaaaaa actaagattt
     3661 ctcactaatt ctgctagttt aaagattttt aaataaattg gataaaagat ttaaatttta
     3721 attcaaaaca tgttataatc atacagtatt ctattttaga aagcagtgtg actatgaatt
     3781 tttctttttt acctaagtat ttaccttatt ttaactatgg ggctgttgtg acgattctta
     3841 tttctatctg tgttatcttt ttgggaacta ttttgggtgt tgtcttggct tttgggcaac
     3901 gttcaaagtt taaaccgctt gtttggttgg ccaacttgta cgtttggatt ttccgtggga
     3961 caccgatgat ggttcaaatt atgattgcct ttgctcttat gcatatcaat gctccgacta
     4021 ttcagattgg aattttaggt gttgattttt cgcgtctgat tccagggatt ttgattatct
     4081 ctatgaatag tggtgcttat gtttcggaga ctgttcgtgc cggaatcaat gcggttccaa
     4141 aaggtcagct agaggcggct tattcgctag ggattcgtcc taaaaatgcg atgcgttatg
     4201 tgattttgcc acaagcaatc aaaaatatct tgccagcatt ggggaacgaa tttatcacca
     4261 ttatcaagga cagctccctc ttatcagcta ttggggtcat ggagttgtgg aatggggcta
     4321 caacagtttc tacaacaacc tatctacctt taacaccact tttatttgca gcattttact
     4381 acttgattat gacctctatt ctgacagtag ccttgaaagc ttttgaaaaa catatgggac
     4441 aaggagataa gaaataatga cagaaacctt gataaaaatt gaaaatttac ataaatcttt
     4501 tggaaagaat gaagtattga agggaatcaa cctcgagatt aaaagaggag aagttgtcgt
     4561 tatcatcggt ccttcaggga gtgggaaatc taccttgctt cgctctatga atttgttgga
     4621 ggaagcaacc aaggggaagc ttatctttga gggagtcgat attacggaca agaagaatga
     4681 cttgtttgcc atgcgtgaga agatgggcat ggttttccaa caatttaacc tctttcctaa
     4741 tatgactgtg atggaaaata ttaccttgtc acctatcaag actaaaggtg aaagcaggga
     4801 agttgctgag aagagagccc aagagctttt ggaaaaagtt ggtttgccag ataaggcaga
     4861 cgcttatcca cagagtctgt cgggtgggca acaacaacgg attgccatcg cgcgtgggtt
     4921 ggctatggaa ccagatgttt tgctctttga cgaaccaact tcagccttgg atcctgaaat
     4981 ggtaggtgag gtattggctg ttatgcaaga ccttgccaag tcagggatga ctatggttat
     5041 cgtaacacat gagatgggat ttgcccgtga ggtggcagat cgtgttatct ttatggcaga
     5101 cggtgtggtt gttgaagatg ggacacctga gcagattttt gaacaaaccc aagaacaacg
     5161 gactaaagat ttcttgagta aggttttata atctatttta aaatttcaag acaagattag
     5221 tgaaaagttc aaccagagct ttttcttata gtttgaaact ataggataac ctaggaaaga
     5281 agtgttagag ggcactagca gtttttggta taatggaaga tatttgaaag aaaagagaag
     5341 tgatatgaca cagattattg atgggaaagc tttagcggtc aaattgcagg ggcagttggc
     5401 tgaaaagact gcaaaattaa aggaagaaac agctctagtg cctggtttgg tagtgatttt
     5461 ggttggggat aatccagcca gccaagtcta cgttcgcaac aaggagaggt cagctcttgc
     5521 ggctggttcc cgtagcgaag tagtgcgagt tccagagacc attactcaag aggaattgtt
     5581 agacctgatt gctaaatata atcaggatcc agcttggcat gggattttgg tccagttgcc
     5641 attaccaaaa catatcgatg aagaggcggt tttattagcc attgacccag aaaaggatgt
     5701 ggatggtttc catcccttaa acatgggacg tctttggtct ggacatccag tcatgattcc
     5761 ctcgacacct gcaggaatta tggaaatgtt tcatgaatat gggattgact tggaaggtaa
     5821 aaatgcggtc gtcatcggtc gttcaaatat cgttggaaaa cctatggctc agcttctttt
     5881 ggctaaaaat gcgacagtaa ccttgaccca ctcacgaact cataatcttg ccaaggtggc
     5941 tgctaaagca gatattcttg tagtcgcaat cggccgcgcc aagtttgtga ctgctgactt
     6001 tgtcaaacca ggtgcggttg tcattgacgt tgggatgaac cgagatgaaa atgggaagct
     6061 ctgtggagat gttgattatg aggcagttgc accacttgct agctatatca cgccagtccc
     6121 tggaggtgtc ggtcctatga ccattaccat gctgatggag caaacttatc aagcagcact
     6181 tcggacattg gatagaaaat aagagaaaca ttcgattaat agagtgtatt ttctatagct
     6241 atatctaaaa tggcagaaat gaatattaaa ttttagatat aagattacaa aaggaggtct
     6301 gcgtctcctt tttattgtat aataaaagtg agaggaaaaa aggatgaaag tgattaatca
     6361 aaccttatta gaaaaagtta ttattgaacg ttctcgttca agtcataaag gagattatgg
     6421 tcgtctgctg ctgcttggtg gtacttatcc ttatggaggt gccatcatca tggctgcttt
     6481 agcagctgta aaaagcggtg caggattggt gaccgttgga acggacaggg aaaatatccc
     6541 ggctctgcac agccatttac ctgagcctat ggccttttct cttcaagacc agcaattgtt
     6601 aaaagagcaa ttggagaagg cagaagttgt cttgttgggg cctggtttac gagacgatgc
     6661 ttctggagaa aatctagtaa aacaggtctt tgttaattta agccaaaatc agattttgat
     6721 tgtagacgga ggtgccttga ccattcttgc taggacaagt ttgtcatttc cctcaagcca
     6781 gcttatccta actcctcacc aaaaagaatg ggaaaaatta tctggaatta cgattgaaaa
     6841 gcaaaaggaa gatgcaacgg ctagtgttct gacttccttc cctcaaggaa caattttggt
     6901 ggagaaaggc ccagctactc gtatttggga agttggccaa tctgattatt accagttaca
     6961 ggttggtggt ccttatcagg cgactggggg aatgggagat actctggctg ggatgatcgc
     7021 aggatttgta ggccaattcc gacaggccag tctctacgag cgtgtggcag tagcgaccca
     7081 tcttcattca gccatagccc aagaactatc tcaagaaaat tatgtggtct taccgacgga
     7141 aatcagcagg tatcttccca aaataatgaa aattatttgt caacaagaga gggtaagcaa
     7201 agataaactt gtttaaaata gacagataaa tctacttcct tctcttaatt tatgattctt
     7261 gaaatgcgcc tgctttaagg ctaaactaga cgtatcaaag ttaagagttt gtttttgtaa
     7321 ctggaaagag atgaacaaat caaatacata aaagataaac tcatttttat tcgtttggta
     7381 aaaataaaat gcatattttt aaagaaagat tgatgaaaaa tgtagatttg atgtttttac
     7441 ttgaataaaa agcggtttca tagtaaaata agaactgaga atgatggagg taaatcggtg
     7501 gaaaatctga agaaaatggc aggtatcaag gctgctgagt tcgtgagcga tggaatggtc
     7561 gttggacttg gaacaggctc gactgcctat tattttgtcg aagaaatcgg tcgtcgtatc
     7621 aaggaagaag gattgcagat tacagctgta acaacttcta gtgtgaccac taaacaggca
     7681 gaaggcctta atatcccgct caagtctatt gaccaagtag actttgtcga tgtgacggtt
     7741 gatggcgcgg atgaagtgga tagtcagttt aatggaatca aaggcggtgg tggtgccctt
     7801 ctcatggaaa aggtggtcgc aacaccatca aaagaataca tttgggtggt ggatgaaagc
     7861 aagctggtcg aaaaactagg tgcttttaaa ttgccagtag aagtggttca gtatggtgca
     7921 gagcaggtct ttcgtcattt tgaacgagct ggctacaaac caagtttccg tgaaaaagac
     7981 ggccaacgtt ttgtgacgga tatgcagaat tttatcattg acctcgcctt ggatgtcatt
     8041 gaaaatccaa ttgcttttgg acaagaattg gaccatgtcg ttggtgttgt ggagcatggt
     8101 ttattcaacc aaatggtgga taaggtaatc gttgctggac gagatggagt tcagatttca
     8161 acttcaaaaa aaggaaaata gaagggggca taagatgtct aaatttaatc gtattcattt
     8221 ggtggtactg gattctgtag gaatcggtgc agcaccagat gctaataact ttgtcaatgc
     8281 aggggttcca gatggagctt ctgacacact gggacacatt tcaaaaacag ttggtttgaa
     8341 tgtcccaaac atggctaaaa taggtcttgg aaatattcct cgtgaaactc ctcttaagac
     8401 tgtagcagct gaaatcaatc caactggata tgcaacaaaa ttagaggaag tatctcttgg
     8461 taaggatact atgactggac actgggaaat catgggactc aacattactg agcctttcga
     8521 tactttctgg aacggattcc cagaagaaat cctgacaaaa atcgaagaat tctcaggacg
     8581 caaggttatt cgtgaagcca acaaacctta ttcaggaacg gctgttatcg atgattttgg
     8641 accacgtcag atggaaactg gagagttgat tatctatact tcagctgacc ctgttttgca
     8701 gattgctgcc cacgaagaca ttattccttt ggatgaattg taccgtatct gtgaatacgc
     8761 tcgttcgatt acccttgagc gtcctgccct tcttggtcgc atcattgctc gcccttatgt
     8821 aggtgaacca ggtaacttca ctcgtacggc aaaccgtcgt gacttggctg tatctccatt
     8881 ttccccaact gttttggata aattgaatga ggctggtatc gatacttatg ctgtgggtaa
     8941 aatcaacgat atctttaacg gtgctggtat caaccatgac atgggtcaca acaagtcaaa
     9001 tagtcatgga attgatacac tattgaagac tatgggactt gctgagtttg aaaaaggatt
     9061 ctcattcaca aacctagttg actttgatgc cctttacggc catcgtcgta atgctcacgg
     9121 ttaccgtgat tgtttgcatg agtttgatga acgcttacct gaaattatcg cagctatgag
     9181 agagaatgac cttctcttga ttactgcgga ccatggaaat gacccaacgt atgcagggac
     9241 ggatcacact cgggaatata ttccattgtt ggcatatagc cctgccttta aaggaaatgg
     9301 tctcattcca gtaggacatt ttgcagatat ttcagcgact gttgccgata actttggtgt
     9361 ggaaactgct atgattgggg aaagtttctt agataaattg gtataagatg acgcgctatg
     9421 ctttgctggt gagaggtatc aatgttggta gtaagaataa ggtcgttatg gcggagcttc
     9481 gtcaagaatt gacaaacttg ggactggaaa aggttgagag ctacatcaac agtggcaata
     9541 ttttctttac ttcgatagat tccaaagccc aattggttta aaagctagag actttctttg
     9601 cagtccatta tccatttatt cagagctttt ctttactgag tctagaggac tttgaggcgg
     9661 aacttgaaaa tctaccagct tggtggagca gagacttggc acgaaaagat tttctctttt
     9721 acactgaggg tttggatgtg gaccaagtca tcgcgacagt tgaaagttta gagctgaaag
     9781 atgaagtgct ttattttaga aaacttggga ttttctgggg gaaattttct gaagaatcct
     9841 attctaagac tgcctatcat aagtacttgc tgaaggtgcc tttctaccgc cacattacta
     9901 ttcgtaatgc taaaaccttt gacaaaattg gtcaaatgct aaaaaataat aaaggagaca
     9961 cataatgaca tttttaaaca aaatccatga aactgctact ttcctgaaag aaaagggaat
    10021 tgcagcccct gagttcggtc taatccttgg gtcaggactt ggagaattgg cagaagaaat
    10081 cgaaaatcca gttgtagtag actatgctga gattccaaac tggggccgtt caacagtagt
    10141 cggtcatgct ggtaaattgg tatatggtga actggcaggt cgcaaggtct tggctcttca
    10201 aggtcgtttc catttctatg aagggaatcc tctggaagtg gtgactttcc cagttcgtgt
    10261 gatgaaagtt cttggatgtg aaggtgttat tgtaaccaat gcagctggcg gtatcggatt
    10321 tggtcctggt accttgatgg ctatctcaga ccatatcaac atgacggggc aaaatccatt
    10381 gatgggtgaa aacttggatg actttggccc acgtttccca gatatgtcta gggcctacac
    10441 accagaatac cgtgccactg cccatgaagt ggctaaaaaa cttaatatca agcttgatga
    10501 aggtgtctat atcggagtta ctggtccgac ttatgaaaca ccagcagaaa ttcgttccta
    10561 taagacactg ggagcagatg cagttggtat gtctacggtt cctgaagtta tcgtggcagc
    10621 ccactctggc ttgaaagttc taggaatttc atgtatcact aactttgcgg ctggtttcca
    10681 agaagaactc aatcacgaag aagttgtaga agtgactgaa cgtgttaaag gtgatttcaa
    10741 aggcttgctt aaagcgattc ttgctgaatt gtaagaaaaa agatttaaaa ggggaagtac
    10801 ctctgttttt tcaggattga ctgcctatcc ggattaaaga agaaacagag gaatactatg
    10861 agcttcttcc tgctcttata actgaaagaa gcggaagaat aggtatgtct gatctgatag
    10921 ccagcattgt gaaagacaag attctaggat actagcatta gcttcctagc caagcagact
    10981 agtatgataa ggagagatga gaatgaattg actttctgaa tttctcagtc ttatcatata
    11041 tagcacaatg agatttcgct tgagtctgct tgtaaataaa cgaaaagaaa gataagaaat
    11101 aatgaaaatt ggtcaacgaa ttatgcgctt tggcataaaa aattaagtat cggagttgta
    11161 tctgttgtag tcggctttga tttctagctc cagctggaat ttcagccaat gaagtaaagt
    11221 aagatgtaac atctgaagtg gtaataggtg tgttagattc taaggaggaa ttgaaagagt
    11281 cagaaaatga tgctctaaaa ctagaaactc ctcttagaga ggagccaaga ctagctcctc
    11341 aaacgcttcc ggaagcaagt gaagttagtt cttgaaaaca aaagggaaga gtcaaaagta
    11401 gagataacag aaccagctca agcggatgat atccgcaagg ttgttgggga attagccaag
    11461 gatataagta ttactaagtt gtatatgaca ggtcattttc ttggatgtta cctagctcag
    11521 attgcagcgg ttgaagctta ccaaaaatat cctgattttt ataaccatgt attgaggaga
    11581 gtgacaactt tcagtgctcc taaagtgatt acttccagaa ctgtttggaa tgctaagaat
    11641 ggtttctggg atgttggttt ggaaagtcgt aaattagctg ttagtggaaa aattaagcat
    11701 tatgtggttg ataatgacaa tgttgtgact cccttgattc ataatgatcg tgatattgtt
    11761 acatttacag gtaattcacg ctttaaacac cgttctcgtg gctattttga aagtccaatg
    11821 aatgatattc ctaactttaa tattggtaaa caagctacct ttgataaaca tggttatcgt
    11881 gatccgaaat tggataaagt gcgattcttt aagaaacagg ctctacctca atcttctagt
    11941 caaccaagcg ctgaaccaat ggaaaatatt gccttaggaa aacaggttac tcaaagttcg
    12001 acagctttcg gaggagatgc tagaagagct gtggatggca aagtcgatgg taactatggt
    12061 cacaattctg tcactcatac aaacttccaa tctaagcctt ggtggcaagt agatttggct
    12121 aaagaagaaa ccattcgcca aatcaatatt tacaaccgaa cagacactgc ccaggataga
    12181 ttggcaaact ttgatgtcat tcttttagac agttctggta aagaaattga gtgaaaacgt
    12241 ataacatctc ctaaagatgt gtcagcacaa attacgatta accataaaaa aagcgcgcta
    12301 tgttcggatt gagctagaag gctataatgc cctcagtctt gcagaagttg aagttttccg
    12361 ctttatagct acgaatggtg aaacggcgat acaagtttct aagtcagttc aaccaatcag
    12421 tcagactcct gtgaaagata aaacattgac aattcaacac agtggagctt acattgcccg
    12481 ctactccata acttgggaag aagttacagt agataaagat ggaaaccaag ttgttcgtag
    12541 tcattcttgg gaaggaaacg gtcgcaacca gactgcaggt tttgtcctca acctcccaat
    12601 caaagaaaat atgagaaatc tgcgagttaa gattgagaaa aagacgggcc tactatggaa
    12661 tagatggcaa acaatctatg aaaacagacc aattttagct caaccccacc gtaaaattac
    12721 ccattggggt acgacattga attccaaggt gagtgacgat gatgtcttgt aatctgatgg
    12781 tagaatgaca gttagtttgt ctagtttata agaaagtact acctgagctt gaatagaact
    12841 caggtagctc tctatgaaag aacaaaatta atactcaatg aaaatcaaag agcaaactag
    12901 gaaactagcc gcaggttgct caaagcacta ctttgaggtt gtagataaga ctgacgaagt
    12961 cagtcacata tataatccaa ggcgacgttg acgtggtttg aagagatttt agaagagtat
    13021 aaacagaaag gtagagcgcg tgttctaatt tgaacacgag tagaaaactt ttctaaaaac
    13081 aaaaacgaaa ggatgggtaa actgtattcg ctgaactgaa tacgggcgac tctcctctaa
    13141 atcaaaatta agaaaggaat tgaccccacc ctaaaagtag tgggaaaaag atagttggtc
    13201 tagcgagcat cgctcactgc gcccaactcc tattttccct tcgctttttg atgggtttgg
    13261 tatctttctc aatataaaat ataaaataaa gaaaggtaga gcgcgtgttc taatttgaac
    13321 acgagcggaa aactcggaaa atagataatc tgactgaaaa atcaggattt ctcgtcaggt
    13381 tcctaatttt cagtcgtttt cttctcgctc tttgtatcat aaattatgtc tatccatatt
    13441 gctgctcagc agggtgaaat tgctgataaa attcttcttc ctggggatcc tcttcgtgct
    13501 aagtttattg cggagaattt ccttgatgat gctgtttgtt ttaacgaagt gcgtaacatg
    13561 tttggttaca ctggtactta caagggtcac tgtgtatctg tcatgggaac tgggatggga
    13621 atgccatcta tttcgattta tgcgcgtgag ttaatcgtag actacggtgt gaagaaattg
    13681 attcgtgtgg gaactgcagg ttctttgaat gaagaggttc atgttcgtga attagttttg
    13741 gcgcaggcgg ctgcaaccaa ctcaaacatc gttcgtaatg actggccaca gtacgatttt
    13801 ccacaaattg ctagctttga tttgcttgat aaagcctacc atatcgccaa aaaatttggt
    13861 atgactactc acgttgggaa cgttttgtca tctgatgtct tttactcaaa ttactttgaa
    13921 aagaatatcg agcttggtaa atggggagtc aaggctgtgg aaatggaagc agcagctctt
    13981 tactatcttg ctgcccaata ccatgttgat gcgctagcta tcatgaccat ctctgatagc
    14041 ttggtcaatc cagacgaaga cacaactgca gaagaacgtc aaaatacctt cactgatatg
    14101 atgaaggttg gtttggaaac cttgattgca gaataattat agccaaaaag gaagcccttt
    14161 atgaattgta ggacttcctt ttcttatcca gaaattgatc tagttctctc tgatttcgaa
    14221 gaatagtgac tttatgtgaa tattcttggc aaagtttttg gtaattttct ttttgagttt
    14281 tgctacgccc atcccaaaga atccatctga taaactccca ctcaaagcgt tcagggcaat
    14341 ctgccgccat actttctctg acttttccac ggtatttaag ataacgctta aaggctctaa
    14401 agagacaggt caatggcaaa aaattgagaa agatgatttg gtcagcttct tgcattcgtt
    14461 cttggtagta gcaccaagaa taattaccat cgatgaccca agctttatgc ttggtgagaa
    14521 agttttttat ctcggttaac atccattcgc agtcactgtc ttgccaacca ggttgaaatt
    14581 ggagtgtgtc catgtgcagt tttggaatgg agtagtagtt agataacttt tctgctagag
    14641 ttgacttacc agaaccagaa tatccgataa ttgtgatttt cattttctac cttttcctat
    14701 ttggagacaa aaaaacagcc tctatggact gtttcttatt tagcaagttt agctgaaaga
    14761 cgagctttat cgcggcttgc tttgtttttg tgaatcaaac ctttagtttc tgctttatcg
    14821 atagctgagc tagcagcacg gaaaagttct tcagatgggt ttgcttcaaa agcttttata
    14881 gcagtacgca tagctgattt ttgagctgag ttcttttcgt tttgtttaac gttcaattca
    14941 gcgcgtttga tagctgattt aatgtttgcc aatgttctta cctccatatt tactaactat
    15001 accattatat atgaaaactt acgttttgac aagggaaaat tattttttta agtaaatttc
    15061 atcgatttca tggttcttgc ttttatgaag aatcacttct gcacgatttc tggttggttc
    15121 aatataattt tgtagatttg tgagattgat actggtccag acctgatggg caaaggcttc
    15181 cacttcccca atcggcatct gagtaaaacg ataatagtag ctatcagggt cgttttgggc
    15241 tagactcagc attttcaaga aacggtccag ataccaactt tcaatatcat ccactccagc
    15301 atctacatag atggaaaagt caaagaagtc agtgatatag agacgatcgt tttgtggatt
    15361 ttgaaagaca ttgattccct caacaattac aaaatcagca gctttgacac tttgtttctc
    15421 ttcgggtacg atgtcgtaaa cttcatgaga atagacagga atatctacat cttgtccatt
    15481 tttgatgcgg tccaagaagt tgagaagagc ttccatatca tagctttcag gaaatccttt
    15541 acgatttaaa atcccctgct caatcaaggt ttgattggga tagagaaaac catcagttgt
    15601 aaccaactca accgtagcat ctgtaaacgt acgggacagt aggatttgaa gtaggcgact
    15661 ggttgtggat tttccaacgg caacactccc agaaacccca ataataaaag gttgagattt
    15721 actttcacgt tggaggaaaa ttccttttga aaaggctaaa tcttccttag ttcgcttgta
    15781 aatctgaatc agatgagcca aggggagata gatatctgta acgtcttgga gactgatttg
    15841 gtcattaaaa ctcttgatag attccaattc ttcttctgtc aaaggaggtg ttgtctttcg
    15901 atgtaaagat tgccaagtct ggcggctgat tttttcaaaa tgtaaaaatt cgttggtcat
    15961 ttgttttccc ctagatattt tgtctatcat accataaaaa tctaaaaaaa taaagcggtt
    16021 tcttgaatgt ggtaagtcaa tggtatatag tataagtgat caatttattg atgaaatagg
    16081 agatagattc tactgattta taagtttata agcttataaa gggggctttt tagttcacaa
    16141 cttataggag gtgtactatg aaaatcttaa aacgttacat attggaactc tgttttattt
    16201 taagttttgc tttacctttt ataaaaggag ccaatgcaga taatggtaga tgctttgtgg
    16261 aaacctatta tggttttact tttttgatgg aacatgctat tgtaacagct gtctttatct
    16321 gttcgctctt aattgctttc ttactaaaaa aaacgatggg cgaaatggat tgctgctggt
    16381 agttattgct ttttagtcct atggattgcg acagagggtt atttcttccg catgtcacta
    16441 gaagatttga tacgactttg gacaagtttg gaaatcctga cacaaacgta tcagttgggc
    16501 ttttatctaa acattttgtt gggaattttg ttgataataa agtattttaa ggttaagcaa
    16561 tagaaataat aatctgcctg attatagatg ataaactttt tgtttttatc tggactgtga
    16621 tatttatagt tctaaatggt ttattattta taagtgttga aagagattga agaaaatggc
    16681 ttcgtgactc gctttcttcg gtctttttcg ttttattatc aatttgtaaa cgatttacaa
    16741 tttgagtcaa attatggtaa aatagtgtca tgagtaaaat gtattatgca gaaaatcctg
    16801 acgctgctca cgacattcat gagttgagag tagagttgtt gggacaaaaa atgacctttt
    16861 taacggatgc gggtgttttt agcaagaaaa tagttgactt tggaagtcaa ctattgctca
    16921 agtgtcttga ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt tacggacctt
    16981 tgggtttgtc cttagctaag gcttatggag ttcaggctac tatggttgat atcaacactc
    17041 gtgccttaga tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg acgattttcc
    17101 agtccaacat ctatgaacaa gttgaaggac attttgatca tgtcatttcc aatcctccta
    17161 tccgtgcggg caagcaagtc gttcatgaaa tcattgagaa aagtaaagat ttcttggaaa
    17221 ctggtgggga tttgacaatc gtcatccaga aaaaacaagg ggctccaagt gctaagtcca
    17281 agatggagga tgtgtttggt aattgtgaaa tccttaaaaa agacaaagga tactatatcc
    17341 ttagaagtgt gaaagaatga gagcagttga tttaatacaa aaaaaacgag acggtcaaga
    17401 actgacttca agtgaaattg aatggctggt agaaggctat gtgtcaggaa ctgttcctga
    17461 ttatcagatg tctgcctttg ctatggctgt ttattttaaa ggaatgacga ctcgtgaaat
    17521 ttctgattta acgatgaata tggttaagac tgggcaagag tttgacctgt cagccattga
    17581 tggtgtgaaa gttgacaagc attctactgg tggtgtcggc gataaggtaa ccttgatttt
    17641 agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc gtggtcttgg
    17701 ccatacaggc ggaacaattg ataaattgga gtccattaag ggctatcaag tagaacgtag
    17761 tcaagaggat tttattcgtc aggttcagga tattggagta tctgtcattg ggcaatcaga
    17821 ccagctggtc aaagcagata agcttctcta tgcccttcgt gatgtgaccg caactgtcga
    17881 cacgattcct ttgattgcga gttcggtgat gagcaagaaa attgcggcag gggcggatgc
    17941 tattttgcta gacgtgactg tcggtgaggg tgccttcatg aagacggttg atgaggcgcg
    18001 tgagttggct caaactatgg tagatcttgg taaggttgtt ggacggaaga cagtagcagt
    18061 gattacggat atgagccagc ctttgggacg agcgattgga aatcgtctgg aaatccttga
    18121 agcattggag attttgcaag gtcaaggacg tcaggatatt acccacttta tttgtgaatt
    18181 ggctcaaatt atgcttggtt tggcaaatgt taacaaaact gttgaagaag ttcgccaaca
    18241 tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc aaggtggaga
    18301 cttggaagac ctctattgtc ctgtaaatgt agctcatgtg gtggaaatcc ctgctcagga
    18361 aacgggtgtc atttcagctc ttccagctat ggactttggt ctttatgcca tgaggctggg
    18421 tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa acaggaattg tttttgaaaa
    18481 gaagattgga gactccgttc aaaagggtga aattgttgca aaagtataca caaatgaaaa
    18541 aattccacct caactagtta cagatttcca aaaatgtgtt aaaataagtg atgaagtgaa
    18601 aaaaatccgt gaaattgtag aaatcatctc ctaaatggag ggaaaaccga aatgaaatta
    18661 aataaatata tagatcatac gcttttaaaa caagatgcaa agaaaaaaca aattgatagt
    18721 ttgttgtctg aggctagaga gtatgacttt gccagtgttt gcgttaatcc gacctgggtt
    18781 gaacatgcta aaaaaggact tgaaggcaca gatgttaagg tttgcacagt agtaggtttc
    18841 cccttgggag caacaacttc aactgtgaaa gcttttgaaa caaaagaagc tatccaaaat
    18901 ggggctgatg agattgacat ggtaatcaat gttggggctc tcaagtcagg tgatttggcc
    18961 ttggttgagt cggatattcg tgcagtagtg gaagcaagtg gggacaagtt agtgaaagtc
    19021 attattgaag cttgccttct gacagaccaa gaaaaagttt tggcttgcca attagcccaa
    19081 aaagcaggat ctgactttgt caaaacatct actggctttt caactggtgg tgctacgata
    19141 gcagatgtta gattaatgcg tgaaacagtt ggatctgata tgggagtcaa ggctgctggt
    19201 ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac ccgtatcgga
    19261 acgtcagctg gggtagctat tttaaaagga gaattggcag atggcgacta ctgagttgat
    19321 tgaactggca attgaaacca gcaaacatgc ctatgtcccc tattctcact ttcctatcgg
    19381 agcagtttta gtagccaaag acggaagtgt ttacacggga gtgaatatcg aaaatgctag
    19441 ctatcctttg accaattgcg gtgagagaac agctattttt aaggctatat ctgaaggcca
    19501 aagagaattt tcagaattga ttgtctatgg tcaaactgaa aaaccgatct cgccatgtgg
    19561 tgcttgtcgc caagtgatgg ctgaattttt tgaacaagat ctaaaagtga ccttagtcgc
    19621 aaaagataaa tcgacggtcg agatgacggt cggggaatta cttccatact cttttacaga
    19681 cttaaactag tctgagtcgc tctctgagtg gcacggtcct tgtggccaac caatccatac
    19741 ttgcaacatc gttgcacatc ttatttagga ggttcagtaa tgaacaagaa acaatggcta
    19801 ggtcttggcc tagttgcagt ggcagcagtt ggacttgctg catgtggtaa ccgctcttct
    19861 cgtaacgcag cttcatcttc tgatgtgaag acaaaagcag caatcgtcac tgatactggt
    19921 ggtgttgatg acaaatcatt caaccaatca gcttgggaag gtttgcaggc ttggggtaaa
    19981 gaacacaatc tttcaaaaga taacggtttc acttacttcc aatcaacaag tgaagctgac
    20041 tacgctaaca acttgcaaca agcggctgga agttacaacc taatcttcgg tgttggtttt
    20101 gcccttcaca atgcagttga agaagcagct aaagaacaca ctgacttgaa ctatgtcttg
    20161 attgatgatg tgattaaaga ccaaaagaat gttgcgagcg taactttcgc tgataatgag
    20221 tcaggttacc ttgcaggtgt ggctgcagca aaaacaacta agacaaaaca agttggtttt
    20281 gtaggtggta tcgaatctga agttatctct cgttttgaag caggattcaa ggctggtgtt
    20341 gcgtcagtag acccatctat caaagtccaa gttgactacg ctggttcatt tggtgatgca
    20401 gctaaaggta aaacaattgc agccgcacaa tacgcagccg gtgcagatat tgtttaccaa
    20461 gtagctggtg gtacaggtgc aggtgtcttt gcagaggcaa aatctctcaa cgaaagccgt
    20521 cctgaaaatg aaaaagtttg ggttatcggt gttgaccgtg accaagaagc agaaggtaaa
    20581 tacacttcta aagatggcaa agaatcaaac tttgttcttg tatctacttt gaaacaagtt
    20641 ggtacaactg taaaagatat ttctaacaag gcagaaaaag gagaattccc tggcggtcaa
    20701 gtgatcgttt actcattgaa ggataaaggg gttgacttgg cagtaacaaa cctttcagaa
    20761 gaaggtaaaa aagctgtcga agatgcaaaa gctaaaatcc ttgatggaag cgtaaaagtt
    20821 cctgaaaaat aatggatgga agtcatttct taggaagcgg ccaagggccg cttttttaag
    20881 agttgagaca aagtcatttt gtctcagtaa agcttgctac tagacaaact agcaagtttt
    20941 attgaaataa aataagactc tgaaaggaag agcacatggc acacgaaaat gtcattgaga
    21001 tgcgtgatat taccaaggtg tttggtggat ttgttgccaa cgacaaaatc aacttgcacc
    21061 tacgaaaagg tgaaattcat gcacttttag gagaaaatgg ggctggtaag tccacgctaa
    21121 tgaacatgtt agcaggcctt cttgaaccaa ctagtggtga aatcgcggtc aacggtcaag
    21181 ttgtcaatct cgactcccca tctaaagcag ctagcttggg aatcgggatg gttcaccagc
    21241 actttatgtt ggttgaagcc ttcacagtgg ctgaaaacat cattttaggt agtgaattga
    21301 ctaaaaatgg tgtgctagat atcgctggag ctagcaaaga aatcaaggct ctttctgaac
    21361 gttatggctt agctgttgac ccttctgcca aggtagtaga tatctcagtt ggagcccaac
    21421 aacgtgtaga aattttaaaa acactttata ggggggctga tatccttatc tttgacgaac
    21481 caacggctgt tttgactcca tcagaaattg atgagttgat ggctattatg aaaaatcttg
    21541 tcaaagaagg aaaatcaatt atcttgatta cccacaaatt ggatgaaatt cgcgcagttt
    21601 ctgaccgtgt tacagttatc cgtcgtggga aatcaattga aaccgttgaa attgcagggg
    21661 ctaccaatgc tgatttggcg gaaatgatgg taggacgttc tgtttccttt aaaacagaga
    21721 agcaagcctc taaaccaaaa gaagtggttt tgtctatcaa agatttggtg gtcaatgaaa
    21781 accgtggtgt tccagctgtt aaaaatctgt ccttggatgt tcgtgctgga gagattgttg
    21841 gtattgcggg gattgatgga aatggtcagt ctgaactgat tcaagccatt acaggtcttc
    21901 gtaaggttga atctggtagc attgagctaa aaggagattc aattgtaggc ttgcacccac
    21961 gtcagattac agaactaagt gttgggcacg ttccagaaga ccgtcaccgt gatggcttga
    22021 ttttggaaat gatgatatct gaaaatattg cccttcaaac ctactataaa gaaccacata
    22081 gtaaaaatgg aattttgaat tattcaaata ttacttctta tgctaaaaag ctgatggaag
    22141 agtttgatgt tcgcgctgcc agtgaattag ttcctgcagc tgcactctca ggaggaaatc
    22201 aacaaaaagc aattattgct cgtgaaattg atcgagatcc tgatctcctt atcgttagcc
    22261 agccaactcg tgggttggat gtcggtgcca ttgagtatat ccacaaacgc ttgattgaag
    22321 agcgtgataa tggcaaggct gtccttgttg tcagctttga attggatgaa attttaaacg
    22381 tctcagaccg tattgccgtt atccacgatg gtaagattca aggtattgta tcaccagaaa
    22441 caaccaataa acaaggactt ggtgtcttga tggctggtgg aaacttggga aaggagaaga
    22501 gtgatgtcta aaaaattaca acaaatttcg gttcccttga tttctgtatt cctaggaatt
    22561 ttactcggag ccattgtcat gtggatcttc ggttatgatg ctatttgggg ctacgaagaa
    22621 ttgttctata cagcctttgg cagtctgcgt gggattggag aaatcttccg tgctatgggt
    22681 cctctggtct tgattggtct tggttttgcg gttgccagtc gagctggttt ctttaacgtc
    22741 ggacttcctg gtcaggcttt ggcaggttgg attctcagtg gttggtttgc cctgtcgcat
    22801 ccagatatgc cccgtccctt gatgattcta gcaaccatcg tgattgcctt gattgctggt
    22861 gggattgtcg gagcgattcc aggtattctt agggcctatc tagggacgtc agaggttatt
    22921 gtaaccatca tgatgaacta cattgtcttg tatgtaggga atgcctttat ccatgctttc
    22981 cctaaagact tcatgcaaag tacagattcg accattcgtg ttggggctaa tgcaacctat
    23041 cagacacctt ggttggctga gttgactggt aactcacgga tgaatattgg tattttcttt
    23101 gccatcattg ccgttgcagt tatttggttc atgctcaaga aaacaactct tggttttgaa
    23161 atccgtgcag ttggtcttaa tccacatgct tcagaatatg ctggtatttc tgccaagcgg
    23221 actattatcc tatctatgat tatttcaggt gccttggcag gtcttggtgg agctgttgaa
    23281 ggtttgggaa ccttccagaa cgtctatgtt caaggttcgt cattagctat cggatttaac
    23341 ggaatggcgg ttagtttgct tgcggccaac tcaccaattg gtatactctt tgcagccttc
    23401 ctatttggcg ttctccaagt tggggctcct ggtatgaatg cggcgcaggt accatctgag
    23461 cttgtcagca ttgtaacagc gtctattatc ttctttgtca gtgttcatta ccttatcgaa
    23521 cgctttgtca aaccgaaaaa acaagttaaa ggaggtaagt aaagatgtct attataacct
    23581 tgctccccct cttggtgtct tctatgctga tttactcagc acctctcatc tttacaagta
    23641 tcggtggtgt tttctctgaa cgtggtggtg tggtaaacgt tggccttgaa ggaattatgg
    23701 ttatgggtgc cttttctgga gttgtcttta accttgaatt tgcagaacaa tttggagcag
    23761 caactccatg gctatccttg cttgtagcag gattggttgg tagtgttttc tctatcatcc
    23821 acgcagcagc gacggttcat ttccgtgcag accatgttgt cagcggtacg gtattgaact
    23881 tgatggcgcc tgccttggct gttttcttag ttaaagttct ttataacaaa ggacaaaccg
    23941 acaacctaag tcaaactttt ggacgctttg atttcccagt cttggcaaat atcccagtga
    24001 ttggtgatat ctttttcaag tcaactagtc tacttggtta tctggcgatt gccttctcat
    24061 tccttgcttg gtttattctc tttaagactc aatttggtct tcgtctccgc tctgtcggtg
    24121 aacatcctca agcagcggat accttgggaa tcaacgtcta caagatgaga tatttaggga
    24181 ttattatttc aggttttcta ggtggaattg gcggagcgat ttatgcgcaa tcaatctcag
    24241 ttaacttctc agtgacaact attgttggac ctggatttat cgcccttgct gcgatgatct
    24301 ttgggaaatg gaatccaatc ggtgctatgc tttctagtct cttctttgga ctttcacaaa
    24361 gtttggctgt tatcggttct caattgccgt tcctacaagg agtgccagcg gtttatcttc
    24421 aaattgcacc ttatgttttg acaattcttg tcttagcagc cttctttgga aaagcagtcg
    24481 caccaaaagc agatggtatc aactacatca aatcaaaata agcatacaaa aaaacgtcag
    24541 tccaatgact gaactgcccc ccaaaagtta gacagaaaaa atctaacttt tggggtgttt
    24601 ttattatgaa attaagttat gatgataaag ttcagatcta tgaactaaga aagcaaggat
    24661 atagcttaga gaagctttca aataaatttg ggataaataa ttctaatctt aggtatatga
    24721 ttaaattgat t
//
LOCUS       DBEROT010000033        24009 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.33, whole genome shotgun sequence.
ACCESSION   DBEROT010000033 DBEROT010000000
VERSION     DBEROT010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24009
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.33"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1065..1268)
                     /locus_tag="ACL8CG_001540"
     CDS             complement(1065..1268)
                     /locus_tag="ACL8CG_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pncT"
                     /protein_id="HGS1344107.1"
                     /translation="MEKIDYITLNEVELETISGGDDCFIGDIGCIGWGLLKSIGGMIK
                     PAPYVPPVCIPKSSWNPAPPVPC"
     gene            complement(1586..1789)
                     /locus_tag="ACL8CG_001541"
     CDS             complement(1586..1789)
                     /locus_tag="ACL8CG_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HGS1344108.1"
                     /translation="MNTKMMSQFSVMDNEMLDRIEGGIFGVDDALFWAGLGYVAGSIV
                     DTAIDDFTNQCRKNPHQWFCVRV"
     gene            2070..2657
                     /locus_tag="ACL8CG_001542"
     CDS             2070..2657
                     /locus_tag="ACL8CG_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGS1344109.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADNTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            2584..4227
                     /locus_tag="ACL8CG_001543"
                     /pseudo
     CDS             2584..4227
                     /locus_tag="ACL8CG_001543"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            4238..5599
                     /locus_tag="ACL8CG_001544"
     CDS             4238..5599
                     /locus_tag="ACL8CG_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGS1344110.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLETTTDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5656..5784
                     /gene="blpC"
                     /locus_tag="ACL8CG_001545"
     CDS             5656..5784
                     /gene="blpC"
                     /locus_tag="ACL8CG_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGS1344111.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(5855..7195)
                     /locus_tag="ACL8CG_001546"
     CDS             complement(5855..7195)
                     /locus_tag="ACL8CG_001546"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1344112.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKVFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(7209..7946)
                     /locus_tag="ACL8CG_001547"
     CDS             complement(7209..7946)
                     /locus_tag="ACL8CG_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1344113.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYTNSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(7951..8289)
                     /locus_tag="ACL8CG_001548"
     CDS             complement(7951..8289)
                     /locus_tag="ACL8CG_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1344114.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8565..8894
                     /locus_tag="ACL8CG_001549"
     CDS             8565..8894
                     /locus_tag="ACL8CG_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS1344115.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKTETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(9062..10111)
                     /locus_tag="ACL8CG_001550"
     CDS             complement(9062..10111)
                     /locus_tag="ACL8CG_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344116.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10108..10839)
                     /locus_tag="ACL8CG_001551"
     CDS             complement(10108..10839)
                     /locus_tag="ACL8CG_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344117.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVADPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10907..11317
                     /locus_tag="ACL8CG_001552"
     CDS             10907..11317
                     /locus_tag="ACL8CG_001552"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS1344118.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11327..11614
                     /locus_tag="ACL8CG_001553"
     CDS             11327..11614
                     /locus_tag="ACL8CG_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344119.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            11776..12015
                     /locus_tag="ACL8CG_001554"
     CDS             11776..12015
                     /locus_tag="ACL8CG_001554"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344120.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12349..13485)
                     /gene="dnaJ"
                     /locus_tag="ACL8CG_001555"
     CDS             complement(12349..13485)
                     /gene="dnaJ"
                     /locus_tag="ACL8CG_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGS1344121.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13887..14243)
                     /locus_tag="ACL8CG_001556"
     CDS             complement(13887..14243)
                     /locus_tag="ACL8CG_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGS1344122.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(14245..16068)
                     /gene="dnaK"
                     /locus_tag="ACL8CG_001557"
     CDS             complement(14245..16068)
                     /gene="dnaK"
                     /locus_tag="ACL8CG_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGS1344123.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16548..17072)
                     /gene="grpE"
                     /locus_tag="ACL8CG_001558"
     CDS             complement(16548..17072)
                     /gene="grpE"
                     /locus_tag="ACL8CG_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGS1344124.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(17099..18133)
                     /gene="hrcA"
                     /locus_tag="ACL8CG_001559"
     CDS             complement(17099..18133)
                     /gene="hrcA"
                     /locus_tag="ACL8CG_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGS1344125.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKTLQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(18297..18807)
                     /locus_tag="ACL8CG_001560"
                     /pseudo
     CDS             complement(18297..18807)
                     /locus_tag="ACL8CG_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            19415..21748
                     /gene="hsdR"
                     /locus_tag="ACL8CG_001561"
     CDS             19415..21748
                     /gene="hsdR"
                     /locus_tag="ACL8CG_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGS1344126.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYSRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            21761..23224
                     /locus_tag="ACL8CG_001562"
     CDS             21761..23224
                     /locus_tag="ACL8CG_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS1344127.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            23224..>24009
                     /locus_tag="ACL8CG_001563"
     CDS             23224..>24009
                     /locus_tag="ACL8CG_001563"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1344128.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRIVEAIESALEKVDEYAESYNRLEQLDK"
BASE COUNT         7715 a         4818 c         4334 g         7142 t
ORIGIN      
        1 tgaacaccaa caagacgctt aaatcgtgca tcagttagtt atttacttgc ttcataattc
       61 atagaactat agtaaaatga aataagaaca ggataaatcg atcaggacag tcaaatcgat
      121 ttctaacaat gttttagaag tagaggcgta ctattctagt ttcaatctac tatactatac
      181 catattttgt ttcgcaggga atctattata aaagggtaag tatttcaaaa acacttaccc
      241 ctttatactt tattaagctc tactttttat aatacttcaa tccccaaatg aaaggaagat
      301 gttccgtttt ttagcaagaa aagttttcat ttctttgctc ctttcttttt agttaaagca
      361 aaatagatca taactgcaat cacataggct atggtataaa atagctgata ccaaatactt
      421 tccctaagcg gataaagaaa gatggacatg attagataca agatgaaaat gataagtatt
      481 tttttcttca taaaatttcc tcctaaatgt gtgatttatc ttagttgaac aagaatcttt
      541 acactgctag tatagcactc attttgacct tggattactc aaatcatgaa tggtcatcaa
      601 aacatcttga acaataacaa gattttcatc tatacaaaaa tagttatact caacaacaat
      661 caaactaaag aaccaaataa atatagctta acatactttt tttggatttc aagcaatact
      721 gataaaatta ataataaatc tgtggtagta cttcccatcc ctactgcttt ccaattttat
      781 aatattatta attaaataat atatgagaaa aaacgaacaa gactgtgtta ataatctatc
      841 ttattcgttt tatttattag acttgttcag aaattatttg aagcagtatt agctggttag
      901 aaagtgaatt tttaacgttc caaccagcca ttagtttcta gttttcgact cttgcaataa
      961 gctaaaataa tcctgaacaa cacatgtata ttatagttgc gaagattcaa caaaatagcg
     1021 aacaagtcga ttattcattt tttatataag tttacaataa ctttttaaca tggaactgga
     1081 ggtgcaggat tccacgaact ttttggaatg catactggag gaacatatgg agcaggtttt
     1141 atcatccctc cgatactctt caaaagcccc cagccgatac atccgatatc tccaataaaa
     1201 cagtcatctc caccactaat cgtctctaat tctacttcat tcaaagtaat ataatcaatt
     1261 ttttccattg ttataattca ttcctttcgt tttactcaag gcacaacaca gaatgaaaaa
     1321 gtgttgtact ctttatttta taatgtttat aataatagtg agaaaaccta tcactactac
     1381 aaatcacggg gaggtgaata agtgagtgat atagccaata tctcgcattt ttataggtgt
     1441 cattctttct atcaagcaca agaactgtga ctaggagcac gtaaacttat aacagaataa
     1501 gcgactcgtt tgcaaaagaa tagtttctat cactgcatag gtcattaagt tatataaatt
     1561 cttatacaat acaacactac tatatctata cacgaacaca gaaccactga tgaggatttt
     1621 tccggcattg attcgtaaaa tcatcaattg ctgtatcaac aatgctacct gcaacatagc
     1681 ctaaccctgc ccaaaacaaa gcatcgtcaa ctccaaatat tcctccctct atcctatcaa
     1741 gcatttcatt atccataaca gaaaattgtg acatcatttt tgtattcatg acaaatactc
     1801 cttttttatt tttaattttt gtcttgttgc aactttgaca agtttagtat atcattattt
     1861 tttaattttt ttcatccaaa tcttgaattg gcatcgaaac gtcttgaatt agctttttta
     1921 tttcaagcca cctctaaatg tttaaaaaaa ataatttcta atcacttttt taccattcag
     1981 gaagttttaa tgactattca agatttcata aaatatgaac ttagttttat ggcataatat
     2041 acctatccac tatatgaaag gaattgccaa tgacttctta taaacgtaca tttgttcctc
     2101 aaatagatgc gagagactgt ggtgtcgctg ccttagcctc gattgctaaa ttctatggtt
     2161 cagatttttc tctagctcac ttgagagaac ttgcaaagac caataaagaa gggacgactg
     2221 ctcttggcat tgtaaaagcc gctgatgaaa tgggctttga aacaaggcct gttcaagcag
     2281 ataacactct ctttgacatg agtgatgtcc cctatccatt tatcgttcac gttaacaaag
     2341 aaggaaaact ccaacattac tatgttgtct atcaaacaaa gaaagactat ctgattattg
     2401 gtgatcctga cccttctgta aaaatcacta aaatgtcaaa agaacgcttt ttctctgaat
     2461 ggactggagt agctattttt ctagctccca aacccagcta tcaaccccat aaagataaaa
     2521 agaatggtct actaagcaag cttccttcct ctgattttca aacaaaaatc tctcattgct
     2581 tacattgttc tctcaagctt attggtcact attatcaata tcggtggttc ttattatctc
     2641 caaggaatct tggatgaata catcccaaat cagatgaaat caactttagg aatcatctca
     2701 gttggtctgg ttatcaccta tatcctccaa caagtcatga gcttttccag agattatctc
     2761 ctaaccgttc tgagccagag attaagcatt gatgtgattt tatcctatat tcgccatatt
     2821 tttgaacttc ccatgtcttt ctttgcgaca cgtcgtacag gagaaatcat ttcacggttc
     2881 acagatgcta actctattat agatgccttg gcttctacca ttctttctct ttttctggat
     2941 gtttctattc tgattcttgt agggggcgtc ttactggcac aaaaccctaa tctcttcctt
     3001 ctttctcttc tttccattcc tatatacatg ttcatcatct tttcttttat gaagcctttc
     3061 gaaaaaatga accatgatgt catgcaaagt aattctatgg ttagctctgc cattatcgaa
     3121 gatatcaacg ggattgaaac tataaagtcg ctcacgagtg aagaaaatcg ctatcaaaat
     3181 atagacagcg aatttgtaga ttatttggaa aaatccttta agctcagtaa atattctatt
     3241 ttacaaacga gtttaaagca gggaacaaaa ttagttctga atatccttat cctatggttt
     3301 ggcgctcaat tagtcatgtc aagtaaaatt tctatcggtc agctgattac ctttaacaca
     3361 cttttttctt actttacaac tcctatggaa aatattatca acctccaaac caaactccaa
     3421 tctgcgaagg tcgctaataa ccgtttgaac gaagtctatc tagtcgaatc tgaatttcaa
     3481 gttcaagaaa accctgttca ttcacatttt ttgatgggcg atattgaatt tgatgacctt
     3541 tcttataagt atggttttgg acgagatacc ttaacagata ttaatctcac gattaaacaa
     3601 ggagataagg ttagcctagt tggagttagt ggttctggta aaacaacttt agccaaaatg
     3661 attgtcaatt tctttgaacc ctacaaaggg catatttcca tcaatcatta ggatattaaa
     3721 aacattgata aaaaagtctt gcgccgtcat attaattacc taccacaaca agcctatatc
     3781 tttaatggct ctatcttgga aaacttaacc ttgggcggta atcatatgat tagccaagaa
     3841 gatattctaa gagcttgtga attagctgaa attcgtcaag acattgaaag aatgcctatg
     3901 ggctatcaaa ctcagctctc tgatggagct ggtctatcag gaggacaaaa gcaacgaata
     3961 gccctcgctc gtgctctttt aactaaatct cctgttttaa tactagacga agctactagc
     4021 ggtcttgatg tcttgactga gaaaaaggtt atagataatc ttatgtccct aactgataaa
     4081 accattctct ttgtagccca tcgtctcagt atagccgaac gaactaaccg tgtcattgtt
     4141 cttgaccagg ggaaaatcat tgaagttggt agtcaccaag agttaatgca agcgcaagga
     4201 ttctaccatc atctattcaa taaataagga gaatgtcatg aatcctaatc tttttagaag
     4261 cgtcgagttt tatcagagac gttaccataa ctatgcgaca gtgttaatta tacctctttc
     4321 attactattt actttcatct tgattttctc ccttgttgcc acaaaagaaa ttactgttac
     4381 ttcccaaggg gaaatcaccc ctacaagtgt cattgcatct attcagtcga ccagtgataa
     4441 tcctatcctt gctaatcatt tagtggcaaa tcaagtagtt gaaaaagggg acttactcat
     4501 caaatactct gaaacaatgg aagaaagtca gaaaactgcc ttagcaactc aattacaaag
     4561 acttgagaag caaaaagaag gacttggaat tttgaaacaa agcttagaaa caacgactga
     4621 tcttttttct ggcgaggatg aatttggcta ccataatacc tttatgaatt ttactaaaca
     4681 atcccatgat attgaactgg gtatcacaaa gactaacact gaagtttcaa atcaagctaa
     4741 tctttccaat agcagttcat cagctattga acaagaaatt acaaaagttc aacaacaaat
     4801 tggagaatat caagagttga gagatgctat cataaataac agagcacgct taccaactgg
     4861 caatccgcac cagtcaattt tgaatcgtta tcttgtagcc tcacaaggac aaacacaagg
     4921 aactgcagag gagccatttt tatctcaaat taatcaaagt attgcaggtc ttgaatcatc
     4981 tatcgcaagc ctcaaaattc agcaagctgg tatcggaagt gtagcaactt atgataacag
     5041 tttagcaacc aaaattgaag tactccgcac tcagttttta cagacagcct cacagcaaca
     5101 actaactgtg gagaatcaat taacagaatt aaaagtacaa ctagatcaag cgacacagcg
     5161 tttggaaaac aataccttaa cctccccaag taaaggtatc gttcatctga acagcgaatt
     5221 tgaaggtaaa aatagaattc caactggtac agaaattgct caaatattcc ctgtcatcac
     5281 agatacaaga gaagtactaa tcacttacta cgtatcttct gactatctac ctctactaga
     5341 taaaggacaa actgtaagat taaaactgga gaagattgga aatcacggca ccaccatcat
     5401 cggccaactt cagacaattg atcaaactcc taccagaaca gagcaaggaa atctctttaa
     5461 attaaccgct cttgcaaaac tatctaacga ggatagtaaa ctcatccaat atggcttaca
     5521 aggtcgcgtc actagtgtaa ctacaaagaa aacatatttt gattatttca aagataaaat
     5581 tttaacccat tctgattaat tttcagataa cactctataa ctatttatta tcttatcaaa
     5641 aaggagaatc ataacatgga taagaaacaa aacctaactt catttcaaga actaacaact
     5701 accgaactca accaaattac aggtggagga ttgtgggaag atttattata taacattaat
     5761 agatatgctc attacatcac ataagaactt catcatccaa tacaactata aaaaaataag
     5821 accgagaaac aagtactctc ggtcttattt ttcatcattc tgtatgtatc acagtaagta
     5881 cctgacgaaa gacttgattt tgacaggtgg tatttagact ggtattagga tggctttcca
     5941 caatcttcat gacggtatag agaccaactc ctctctcctc ccctttagaa ctggctccaa
     6001 aggagaagat ttcagaaata tcgatgccct cttctttgat ggagttttcg atgataaagg
     6061 tctcctgtgc tccatttttt aaaaaggcga ttgaaacatg aggttgacta gcttccacac
     6121 tggcttcaat agcattgtca caaaggatag acacaatggt tagaaaatca agtagactca
     6181 tcccctcgac ctgaatctcc tcaggaactt cgacattaaa gacaatgttc ttatctctgg
     6241 cttttaaaaa tttccctgct agaagacttt tgagggcttt atcacgaata tttaccaatc
     6301 tgcccaggtc atatttattg ttctgcaatt tctgactgga atcctttaag acggagccat
     6361 agacctcttt tatctgctcc atatcctcct cttcaatgcc cagacgtaag ctagtcaaga
     6421 ggttggtata atcatgacga aagctccgta cttccttgta aagctcctct atatgccgac
     6481 tatagcgttc catatctcta tagcgcaggg cctgctcttg ttccaatctc tcatagagtt
     6541 tttccttcaa ataggtatcc aatttcttga taacccccat aaaaaagagt aggtaaaaga
     6601 ctaggatgag atggcgaaca gtctttgatt gaatactttg ttcatattca aaaaaagaca
     6661 gactttccat gactagatag tagccaccca ttatccagtt aatctgagtc agggactttt
     6721 gaaaggcttt atcgagaatc tcctttctca agctagtaaa atcgtagtcc aaccatttca
     6781 aaaaagctag agaaatgaag aaattgaaaa ttattataca taacccagta aatgagtagc
     6841 catcatatac ttgcccttgt cccaaaaatg gaagcacaaa ataggagact cctctataaa
     6901 agagattcac caatatcatt ggaaagagac cataaaagaa aaggagtttt ttaggaagcc
     6961 ctctcaataa taagaaagat aagcctatgc cgtacaaggg ttccataaaa taagataggt
     7021 aaacatttcc tactatatag ctaatcatca caaaaacaaa ggccaacagt atcttaaaaa
     7081 gaaagacctt aaaaatcctc tcgaaagtaa gatcaattcc atccacctta aagaagatga
     7141 caatttctag tccattagta acaagtgtat acaacaatat ccaagcaatg ttcataaatt
     7201 ctcctagctc agtgtaattt attgatggcc tcagacactt ccctgacctt ataacgggcg
     7261 attagacaac ttccaccatt gggaaagaaa agcagttttt ctttcttatc caaatgcacc
     7321 acatttgcag gattgatgag aaaagagcgg tggcactgca agagacgggg ctcctgcttg
     7381 aaaacctcct ctaaactcgc tgtaaattcc agcctgtctg tcttggtata gagaataaca
     7441 cgatgggctc tgggcgacgt ttcgagatag taaacctctt taaaaggata ctgaaattgg
     7501 gcaaattttg atttaaagta aaagcaatct tccgccagac ttttactatc ttgactattg
     7561 gtatagagga gggctgtctc gatccgagat tcaaactcct ctgctgacaa ggccttatca
     7621 atgtagtcca aagcagacac ttggtagcga aaagacaggg gcataaactc cgagtgagtc
     7681 gtcacaaaga caatcagggc ataaggatcc cgatcccgaa tctttctagc cacttccagt
     7741 cccttcatct cttcatttcg aatctcaatg tccaaaaaga atagctgatg ggcccccttc
     7801 tcatgcacct ctgccagcag ttggtccggc ttgccaaata cctcaaaaga gctaggaatg
     7861 atatgatgtg ctttcaaaag tttctcaatc gtcgtttcaa ttctagtctg ttgggaaaaa
     7921 tcatcttcta aaacaaatat tctcatcttc ttactctccc tctttcaacc atttttgacg
     7981 aatttctcta tagcgacgtc tggcatactt gacagcgtat tgaccttctt ctccgagaaa
     8041 aaggattctt tcttgaaaat caatcgattt taatttatca agattaacca aacaatttcg
     8101 atgacatctc atcaaggttt ccccatattg gttctcaaga ttacttaaat tttgaagcat
     8161 attaaaacta gcttcttctg taacaatctg tacggtatgg gctttagttg gatgtgtttg
     8221 gatatagtag atatcgtcga cgtttacttt atagactgtt ttctgcgtct gaataatcat
     8281 atgtttcatt ggattctcct cctaagaaaa gaataacaga aaagttctag cccaagccca
     8341 cccaatccta aacagtcttt gaaagctcct aaaaggatta ttttctacaa catcatgatg
     8401 agcttacaac tattttatca taaaattcac tcagcgcaat tcaagacatt tcaatgacaa
     8461 ttaaagattt gaataaaaaa aaagaattaa aagtgataaa ctaacagtat caaaacacag
     8521 ttgccagaag taagactggc acccagatta aaggaggcat tcccatgaca gatacagacc
     8581 ccatcaaaag agctcatact ttgattactg acttaaacaa agcctaccaa gcatgcaaac
     8641 aggcaagcgc tgacgacgtc cgctttcagg agcaattaaa ctctattctt ggttttctag
     8701 ccaagactga aacagtggat aatcgattct tgattgaact agaaaaattt taccagactt
     8761 ccagtcttct catgggactc agcgctcttg atccagatgc tccaactcgc gccgcttggc
     8821 gggcctatga ccgcttccac tttgaccaag tcaagaccaa gttaatactc aatgaaaatc
     8881 aaagagcaaa ctaggaagct agccgcaagc tgtacttgag tacggtaaga cgacgctgac
     8941 gtggtttgaa gagattttcg aagagtataa gtctctacgg accaaccatt atcctgtagt
     9001 aacaaaaaag aagttgagac agactgaact caacttcttt tttagtgtcg tatcagcaat
     9061 gttagtcctg catctgacgt tttacctgat aaggcaaata caagactagt aaaaccaaac
     9121 cagctcctag taaggctaga agggctagtt tttcttggaa ggtaatcaac ccaacaacta
     9181 attccacaag taaaacaaaa ctggtcaatc ctcgaactac ctcctgtaag cctttttcct
     9241 tttgcccctt gtccagcgga aagagttggg tcaaatactg gtagtcaaag gcatgataga
     9301 gggccagcaa ctggaagagc aagaggtagt taaagagaac taccactgct gtcgcaatcc
     9361 aagcttgctc gataaaaacc tgcgccagta cggaaagtaa gagaagacga agactgagag
     9421 caaagaggtc gccatttcgc agataagaac gcagatagag attttgccaa atcttcccag
     9481 gcaccttctg aacagccttt aagataaagt ccagataggc acgacgctta acgctgtttg
     9541 aaattccctt gacctgcgta aagagggcaa agaaacgaag caagacttgc ttacgcttgc
     9601 tttcttggga aatgacatag tcccaatcca gtccagtttc agtgaaaaat ttgctggcct
     9661 tttgacgaaa gtggaaatat tttcctaccc ccaataaaag cacatagagc agaaaaactg
     9721 gcaagccata acccattgct aaaaataaag gcgcaaataa cagcaagaaa agggtctgta
     9781 caaagagcca aaagactagg gaaatgccag tttgacgctt gagatggagc ttgatttcct
     9841 cttctccaac taagagaaag agcttgtctg gagcctccat ataggtggca attcctcccc
     9901 aaagtaaaag taaaacagag gtaattccta caaacaaaag gataggccaa tgattttcag
     9961 gaaaatgttg taagagttga ctgtactggt aggctagaaa gcccaacagg acaagcagga
    10021 acaagacaaa gtggtcattg agaacatagc gcagataacc aagacactcc ttacgaaagg
    10081 cctgctttct ctttaaaaac aagtctttca taggtcctcc tcttttgtca gagccaagta
    10141 aatatcattc aaactagcct caggcatatc aaaggcttcg cgtagttgca ggagattgcc
    10201 tttggcacgc acctctccct tgtgaagaat gacaaaggca tcacacatct tctccgccga
    10261 atccagcacg tgggtactca tgagaataga cttgcccttt tgcttctcca cttccaaaag
    10321 ctgaatcaaa tcagaaatag ccagcggatc aagaccaagg aaaggctcat ccacgatgaa
    10381 aagacttgga tccgccacaa aagcacagat aatcatgacc ttctgcttca tcccttttga
    10441 aaaatgaaca gggaaccagt ctaatttctg ttccaaacgg aacattttta acaagggctc
    10501 tactcgttcg aaagccactt tttgctcaat accgtaagcc atagcaaccg tttcgatatg
    10561 ctctctgagg gtcaattcct catacagact aggcgtctca ggaatgtagc caatctgctt
    10621 gcggtagcta gtcgcatctc cttgcagagt caggccattg atattgatgg agccactata
    10681 aggtgccaac agaccgataa tctcattgat cgtcgttgat ttcccagcac cattgagacc
    10741 aatcaaaccg accaactgcc cactttcaac agtaaaggac acatctttca aaacaggaac
    10801 atgaacatag ccacctgtca ggtttttaat ttctaacata ttttctccaa atctggtata
    10861 atgtagctat attatatcaa aattcagtac agtagaggta gattttatgt cagattgcat
    10921 tttttgtaaa atcatcgcag gggaaattcc tgcttcaaaa gtatatgaag atgagcaggt
    10981 ccttgccttt cttgatatct ctcaagtaac actaggacac accttggtcg tgccaaaaga
    11041 acactatcgc aatcttttgg agatggatgc tacgagcgcc agccaactct ttgcccaagt
    11101 accaaaagta gctcaaaaag tcatgaaagt cactaaggct gctggtatga atatcatttc
    11161 caactgtgaa gaagtcgctg gtcaaacagt ttttcatact cacgttcacc ttgtacctcg
    11221 ctacagtgct gacgatgacc tcaagattga ttttatcgcc cacgaaccag actttgacaa
    11281 acttgctcaa gtcgctgaaa ccatcaaaaa cgcttaagga gttgctatga aattatccaa
    11341 cctactgcta tttgcaggag ctgcagccgg aagttatctg gtcacaaaaa atcgccaaac
    11401 catcacagat gaagtcttga ataccactga ccgcgttcaa gctatcaagg acgatgtgga
    11461 tattatccaa aacagcctgc aaatcattga ccagcaaaaa gaacttatca aggaatacca
    11521 agaagacttg acttacaagt ttaaggtctt ggaaaaggat atccagacta gactagctgt
    11581 gataaaagaa atgcagggaa ctgaagataa gtaaaaagag cccgacggct cttttttaaa
    11641 acgtaaacaa gttatagtga attgaattta gaatagcaca tcatagtttc taaagcattg
    11701 ttagagatta ctttaaaatc ctcttatcaa tttgttcata ttctatttca atctactata
    11761 tatatcccat caactatgca tcataattta ggtaactcat actcaataaa aatcaaaaag
    11821 caaactagaa agctaggcac agactgctca aaacaccgtt ttaaggttgt ggatagaact
    11881 gacgaagtca gctcaaaaca ctgttttgag gttgtggata gaactgacga agtcagtaac
    11941 catacccatg acaagccgac gctgacgtgg tttgaagaaa tttttgaaga gtatcattca
    12001 ccatttcaca actaaatcga agactttctg ccgtaatgaa aacacctgaa acagcttggt
    12061 ttcggctatc cggaaacttt aagacttagg ttcaaagttt aggtatggaa cttcgaagga
    12121 ggtcgctacc gtccgtcatt acttaggaaa gtcttaaaaa atctataaag taaaaagagc
    12181 ccgacagctc tttttgttta tactcaatga aaatcaaaaa gcaaactagg aaactagcca
    12241 cgggctgctc aaaacactgt tttgaggttg tagatacgac tgacgaagtc agtcacatat
    12301 atacggcaag gcaacgctga cgtggtttga agagattttc gaagagtatt attctccatc
    12361 aaaggcatct ttaatatggt caaagaagcc ttttttcttt ggatttactt tcaagtcacc
    12421 agcagccgcg aattctttca aggctacttt ttggcggtcg ttcaagcctg tcggtgttac
    12481 gacattaaca gtaacgtatt ggtcaccaac tgcaccgcca cgaaggctcg gtgccccctt
    12541 actacgtagg cggaacttct taccagtctg agttccctct ggaataacca attcaacatc
    12601 accgtgaaca gttggaatat ctactgtatc accaagagcc gcttggacaa agttgaggtt
    12661 gagattgtag aagatagtcg ttccttcacg ttcaaacttg tcgctagctt ccacagaaac
    12721 tactacatac aagtcaccat aaggtccacc gttaaagcct gcttcacctt gaccagcgag
    12781 gcgaatttgt tgacctgttt ccacaccagc agggattttc acatgtacgc tatgagcttg
    12841 tttctcatga cctgttccat gacaggttgt acatggatat ttgatttctt ttcctcgacc
    12901 gtgacagaca tcacaggtta cttggcgacg catcatacca agaggagtct gcgtatcgac
    12961 gttaatgaca ccagcgccat gacagcgtcc acaagtgact ggacttgtcc ctggcttagc
    13021 accagatcca ttacatgtac gacagccagc ttcacgatga tacttaactt ccttctcagt
    13081 tccgaagata gcttcttcaa aggtcaaatt gacacgatac tggagatcat ctccttggcg
    13141 aggagcgttt ggattgcgcg aagaaccgcc tccgccgaag aaacttgaga aaatatcctc
    13201 aaaaccaccg aagccacctg ccccattgaa accgccgaaa ccaccagctc caccaaaacc
    13261 accattggcg cctgcagcac catactggtc ataggcagca cgtttttggt cgtcactcaa
    13321 agtctcatag gcttcttgaa cttccttgta cttgtcctca gcaccaggct ccttgttgat
    13381 atctgggtga tattttttgg aaagcttacg ataagccttt ttgatttcgt ctgccgaagc
    13441 gtttttggat acccccagac gatcataaaa ttcagtattg ttcataattc aagatacaaa
    13501 gggcgtcaaa cggacacagc catctaggag ttttgacgac ggacgcttac gtcctagaaa
    13561 aaactatctt tttggcacag tccatagccc gtgttcagtt acgaacaccc ttattccttt
    13621 ctattgatgt tctgaatcga accaccattt aggtcgggtt caattccttt cttttatatt
    13681 tagtaagaaa ttctgaaacc cgtgttcagt tacgaacact ctttgttcct ttctattgat
    13741 gagacaaaac ccaaacaaat gagattccgt ccctttttat cgaaaaacag aggctgggtt
    13801 gcaacctctg caaataagta aattaacttt attttgattt taaatatcct ataagtacag
    13861 aaatatttat atatttttgt ctcttcttag tatttgccta tataattcca attgatcata
    13921 agaaatacaa ctactgtcca aatcatacca attatgaacg gtattacaaa tttatatgtt
    13981 tgtatttcta atgatatcat agctgatacc atcgctgata caaatgcaga caacaatact
    14041 gaagtaacaa aattccttac cgcttcatca tttttgacac aactatcatg ctcagctaat
    14101 ataatttctc tatatatagt caaacattct actggaatat tatctataaa accttttgct
    14161 gcttcatagt tgtcagcttg attacaaaaa tcattataaa cttttcgtgt attttttaga
    14221 tactcatcat ccaatacact catcttattt ttccgtaaac tctccgtcta cgacgtcatc
    14281 gcctgcgttt cctgttgctt gtgcgccttc tgctccttct tgagcttgtt gcgctgctgc
    14341 ggcttgttcg tagagtttca cagcaaggcc ttgagctttt tcgttcaacg cttcaagttt
    14401 cgctttcatg tcgtccaagt tgttgtcttc ttgagctttc ttaaggtcat caagggcagc
    14461 ttgggcagcg tcacgttctg cgtcgaagcc tttaccttca gtttccttga ttgtcttttc
    14521 agtcgcaaag attgcttggt ctacttcatt acgaaggtct acttcttctt tacgtttctt
    14581 atcggcttca gcgtttgctt ctgcatcttt catcatgcgg tcgatttctt cgtcagtcaa
    14641 acctgagttc gattggatga caatagtttg ttctttttga gttccaaggt ctttggcctt
    14701 aacagacacg ataccgttct tgtcgatgtc aaatgttact tcgatttgag gaattccacg
    14761 aggtgcagct gggatatcag tcaattggaa gcgtccaaga gtcttgttat ctgctgccat
    14821 tgggcgttca ccttgaagaa cgtggatatc aacggctggt tggttgtctg ctgctgttga
    14881 gaagacttgt gatttagatg ttgggattgt agtgttgcga tcgataagtt ttgtaaatac
    14941 tccacccatt gtttcgatac caagtgacaa tggcgttaca tcaagaagga caacgtcctt
    15001 gacatcacca gtaatcacac caccttggat agccgcaccc atagcaacta cttcatcagg
    15061 gtttactgat ttgtttggtt ctttaccagt ttcagcttta acagcttcaa caacggcagg
    15121 gatacgagtt gaaccaccaa caaggataac ttcgtcaatt tctgacaagc tcaaacctgc
    15181 atctgaaagg gcttgacgaa ctggaacttt tgtacgttca acaaggtcac gagtcaaatc
    15241 gtcaaatttc gcacgagtca aagtcatttc caagtgaaga ggtccagcct cacctgcagt
    15301 gataaatggc aagctgattt gtgttgaagt tacaccagaa aggtctttct tcgctttttc
    15361 agccgcatct ttcaaacgtt gcattgccat cttgtcagta gacaagtcga taccgttttc
    15421 tttcttgaat tctgctacca agtggtcaat gattttttgg tcaaagtcgt caccaccaag
    15481 tttgttgtcc cctgcagttg acaatacgtc gaagacaccg tcacccaatt caaggataga
    15541 gacgtcgaat gtaccaccac caaggtcaaa taccaagatt ttttcttctt tgtcagtctt
    15601 gtccaaacca taagcaagag ctgctgcagt tggttcgtta acaatacgtt ctacttcaag
    15661 accagcaatt ttaccagcgt cttttgttgc ttgacgttga gcgtcgttga agtaagccgg
    15721 aactgtgata acagctttgg ttactttctc accaaggtag tcttcagcgt agcctttcaa
    15781 gtattgaagg atcatagctg agatttcttg tggagtgtat tcttttccat ttgcagaaac
    15841 tttttcagaa gttcccatct tagatttgat agagataact gtatctgggt ttgtgactgc
    15901 ttgacgtttt gcagcatcac caacgatgat ttctccgttt ttgaatgaga ctacagatgg
    15961 agttgtgcgg ttcccttctg ggtttgcgat gattttgctt tcagttcctt caagaactgc
    16021 aactgctgag tttgttgtac ctaagtcaat accgataatt ttagacatgt gtttttctcc
    16081 ttgttagtta attttctatt tttctttttg atactcttct taagtggcga cgccgtcaga
    16141 gcttgacttc gtcaatctct ttgactaaac tttgagccta aggtctcaaa atttgcgcaa
    16201 atagcaccac ggcgaagagt atcgtctttg gttcgcttcg ctcactatta caaagccaaa
    16261 catattttat ctttcttcat agtttattgt cgtttcggac aagttttcta ttctgtaaat
    16321 tgcgacacga ggagtcgaaa tcgattttat ttcgacgacg agttagtaag gaagctaggc
    16381 aaacgccata tcgattgccg ttttctgacg agttgcttta gctaccgtca gaattgccga
    16441 atcgaacacg ccctaagctc tgagtaaaaa agatagattt tcttgtgttc atcgaacact
    16501 tcgtcaatct cctattttta ctgcgagctt tttacgagct ttgtatctta gttatacacc
    16561 actaccattg ctgggcgtag gatgcggtca tggagtttgt agcctttttg aaagacttgg
    16621 gcgatggtat ctactgggtg ttcatcgtct gctgggagag tttggatggc catatggtag
    16681 ttatggtcaa attcgccatc tgctgcgatt tcttcaattc cttcttcttt caaagcgtga
    16741 atcaagcttt cttgcaccat cgccaagccc ttcttcacat catctgtcaa accttcaact
    16801 gcaagtgcac gctcaaggtt gtcaagagat ggtaagattg cttttgccaa gtcctggcta
    16861 cgataacgtt gcaagttttg acgttcttca ttggcacggc gttggatatt ttgcatttct
    16921 gcatgagcgc gaagatattt gttttcgaac tcatctgcac gttcatttgc caagtccaac
    16981 tcagactttt caggagttgt ttcttcagct gtttccacaa cttcctcttc ttgaacttct
    17041 tctacttctt cattttttat atcttgggcc atgttcgcct cctttaatga tttcaatctt
    17101 aatgtacttc gtaatgatta ctgctgaggt agcggtaaaa atctgtcaac ttcatggtca
    17161 aaacacggtt gaccacattg acttgattga ttagctgttg gtaatccaga ttaactggac
    17221 cgataatggc tagaattcca actccccgat aaggaatgag gaacttacta ctaatcaccg
    17281 ctaggtcagc taaacaggac tcttgaccgt ctgcaacacg aacattttgc atctgatcct
    17341 cacgcaaccc ctcacgaatc tccaaggcca ccttttgcgg ttggtcaaag aactgatagg
    17401 ctgctagatt ggcaaaattc aagagatgga ccttgcccgc catcacaatg ttttcgttga
    17461 acatttcctt aaagatgtgt tcaaagagat cgatgacatt atccgttgtt gtaaagtaac
    17521 gctggataat ctgcggaatc tccgtccgaa tcttgtagtg aatatctaaa acggtgtgac
    17581 cgaggaaacg ttcctgaatg atgctcttca gtttcagcaa atcctcctgc aagaagttcc
    17641 ttggaatcag aaactgacta gtaaccgttc gcgactcgtc tagggtaaat accgccaagg
    17701 ctgtatgttg ccccaaaaca acgatatcaa aggctgtcaa acgttgcctg ctcggctcaa
    17761 catccagtgc cactaccgta cagccactca ggtctgttag caagttagca gcctcttgca
    17821 gaatatcctc caatttgaag aattcctgat caaaggcttt gacaatctca tatacctcat
    17881 tttcagccag tcggtcaaaa tccagtgagt gtttcacata gtactgaaaa ccagcaacac
    17941 ttggcatccg accgcttgaa gtatgagcct tctcaagcaa cccttgtttt tctagttccg
    18001 ccatgtcatt acgaatggtt gcactgctag agttaataga ctcttgcaag gtttttgatc
    18061 cgacaggttc gtgcgttttg gtaaagatgt caataatcag atttaaaata tcctgctgac
    18121 gctctgtaac catctcatca ctcctctctg tctgatcaat tagcactcaa tgcatccaag
    18181 tgctaactca tgattctatt atacaccctt agaagagaat gtcaagacaa aaactcaaaa
    18241 aattagcact cttttatcaa gagtgctaaa aatcaatctg aagacctaga accttgctat
    18301 tcatctactc ggtatttcct ttttagtctg aaataaccat gaattagata agaaatcaga
    18361 aaagcatata aaacaaaaaa taagaaagaa agacatagaa agatcctctc taaacaaact
    18421 catacaaaca acaagaccac ctaagaaagt agctgtacag gaacgaagtc tagatcgcat
    18481 aacttcccat ttgagcccct tactcatata gacttgatcc tctggaagta aatcagaaga
    18541 cgatttacga agaatcgaac aagaacctgc tcctatcaat tcccaacctc tatctctaaa
    18601 atcttgcagt tcacgcttat gctctttaag aaatctagaa tcatagatac gatagataac
    18661 atcgtccggt tgaccttgct caaaatagaa caaaccaaaa cgactcgttc tatacctcca
    18721 acctttcaaa tgcatctcat gtaaatattc ttctttcttg tccaaatcaa caatggtgaa
    18781 aatccgaaat tctactctgc tattcattgt cttaccccaa aattagaaaa catgcctggc
    18841 gttatttatt agataattct ttccactttt gactcaatct ccaaaaaata taagaaatct
    18901 gaatcgcaaa aactatcaat aaaacccaat ctattatgaa aatcaaaaac actttccaac
    18961 tgaaagaact acctccagta acaaactttg agaaaaacgg tagtagagct aaaaagagaa
    19021 gtaaaatagg aagcatccgc attgttaaaa tccgtttggc ataaaaaaat ctttatttaa
    19081 actaaaatat tatagcaaaa tttacgccag tttttgaacg gctgatgtag atattttata
    19141 ctttcaaaat gtttaaatgt gattatttat ttttgaaaaa tagctcacca gcccgactga
    19201 aagtgcttat agaatgataa taagtcgcct gccgaaaaca gcggaaaata gcggtgttat
    19261 gcggagataa tctgacgcga tgcgaaagta tattgcatac ttattttcaa caatttagca
    19321 gagtattttt ataagtgtga tataatagaa gtataatttg ttctgatagt ttattttatg
    19381 gagaagtaga tttttagaat gcggagggtt caatatggtt gagtttataa agtctaagaa
    19441 agaaatgagt gaggaggata ttaaagcaaa tttcatcact cctgctattg tatccaaagg
    19501 atggaaaaat ggtgagcata tcgcttacga agaatacttc actgatggtc gaattgaagt
    19561 tagaggagat aaggctcgtc gtaaagaagg aaaaaaatca gactattcac tgtattacca
    19621 atttggaact cgaattgcaa ttgttgaggc aaaggataat aaacacagcg ttcgagcagg
    19681 attacaacaa gctattgaat atggagagat tttagatgtt ccatttgttt attcttcgaa
    19741 tggtgatggc tttattgaac acgaccgtat cacgagagaa gaacgtgagc tggagttaga
    19801 cgaattccct actcgtgaag aattattttc tcgtatgacg aaggaaaaag gattgacgta
    19861 cgaaattaca gaagctatct caactccata ctatacagac gccttctcaa tgaaaacgcc
    19921 acgctattat cagcaaatag ctatcaaccg tactattgaa acagttgcca gaggacaaaa
    19981 acgagtaatg tttgtgatgg caacaggaac ggggaaaacg ttcatggctt ttcaaattat
    20041 tcatcgcctt cgaaaagctg gtttggctaa acgagtttta ttcttagcgg atagaaacat
    20101 cttagtagac caaacgatgg ctgaagactt taagccattc gaaaaggtaa tgacgaaaat
    20161 tacaccaaaa cttttgactg ctcctgaaaa attaaattct tttgaaattt atctagggct
    20221 ttatcagcaa ctaactggtg aagatggaac tgaaacacat tatcaaaaat ttgacaaaga
    20281 cttctttgat ttaatcgtaa ttgatgaagc gcaccgtggt tcagctaagg aaaacagtaa
    20341 ctggcgtaag ataattgatt atttcagttc tgcgacacag attgggatga ccgctactcc
    20401 taaagaaacc aagaatgctt ccaatacgga atactttggt gagccaatct atacttatag
    20461 tttaaaacag ggaatcgagg atggtttttt ggctccatat cgtgttatga gggttaattt
    20521 agatgtggat gtggatggtt atcgtccaga aactggaaaa gttgatgcta acggacaatt
    20581 aatagaagat aggtactaca gcaggaaaga ttttgataaa accattgtca ttgatgatag
    20641 aacgcaaaga gttgccaagt ttgtttctga ttatatgaag caaaacaatg cacgatttga
    20701 taaaacaatt gttttttgtg ttgatattga ccatgccgag cgaatgcgtg ctgcacttgt
    20761 aaaagagaat ctagacttag tccaagaaga ctatcgttat gtcatgcaag taactggtga
    20821 caacgctgaa ggaaaagctc aactggataa ctttatggat gtcaattcta attttcccgc
    20881 tattgtaaca acgtctaaat tattaacgac aggagttaat gctaaaacat gtcgtttgat
    20941 tgttttagac tctaatatcc aatccatgac tgaatttaaa caaattattg gtcgtggcac
    21001 acgtctttat cctcaaaagg ggaaagaatt ttttacgatt attgattttc gaaatgttac
    21061 caatttgttt gctgaccctg attttgatgg tgagccagtg aaggtgctgg aaacaggtgc
    21121 gaaaacagtc agtggttcta cgcccggttt cgtagatgag gaaggtgacc cagtagaaaa
    21181 atatatcgtt acagacaagc aggttaccat tcttaattct actgttcaag tattggatga
    21241 aaacgggaaa ctgattaccg aaagcctgac cgactacact cggaagaata tcttaggtag
    21301 ctacgccact ttgaacgatt ttatcacagt ttggcatacg gcggataaaa agaagcttat
    21361 cttagacgaa ctttataaaa aaggagttta tctagatgct attcgagagt cggagggaat
    21421 atcagaacaa gaaatcgatg attttgattt actcctaaaa cttgcctatg gtcaaaaaga
    21481 attaaccaaa acggaacgta tcaataaact caaacaaagc ggatatttat ataaatatag
    21541 tgaggaagcg cgtgctgttt tggaaatttt actgaacaaa tacatggata aaggtattgg
    21601 agaactcgaa agcattgaaa cattaaaact tccagaattt cagatatatg gtggaacctt
    21661 caaaatcatc aatacttatt ttggagataa aaaacgatat ttacaagcaa ttaaagaatt
    21721 ggagcaagag ctatttacag tagcttaatg aaaggaaagt atgtcaatta catcatttgt
    21781 aaaaagaatt caagatatca ctcgaaacga tgctggtgtt aatggtgatg ctcaacgtat
    21841 tgagcaaatg tcttggttat tattcttaaa aatttatgat agccgtgaaa tggtttggga
    21901 attagaagaa gacgagtatg agtcaattat cccagaggaa ttaaaatggc gaaattgggc
    21961 tcatgctcaa aatggggaac gggtattgac aggcgatgaa ttacttgatt ttgtcaataa
    22021 caagttattc aaagagttga aagagcttga aataacttca attatgccta ttcgaaaaac
    22081 gattgttaaa tcagcttttg aagatgcgaa caactatatg aaaaatggcg tcttgttacg
    22141 ccaagtcatc aatgttattg atgaagttga tttcaatagc cctgaagatc gtcattcgtt
    22201 taatgatatt tacgaaaaaa ttcttaaaga tattcaaaat gctgggaact caggagaatt
    22261 ttatacgcca cgtgcagcga ctgattttat tgccgaagtt cttaacccaa aacttggaga
    22321 atcaatggca gaccttgctt gcggaacagg aggcttcttg acttcgactc tgaaccgttt
    22381 aagtagtcaa cgtaaaacta gtgaagatac caaaaaatat aatacagctg tttttggtat
    22441 tgaaaagaaa gcatttcctc atcttttagc agttacaaat ctgtttcttc acgaaattga
    22501 tgaccctaaa attgttcatg gaaatacttt agagaaaaat gttcgtgaat atacggatga
    22561 tgaaaaattt gacattatta tgatgaatcc accttttgga gggtcagaat tagaaacaat
    22621 aaaaaataac tttccagcag aattacggag ttctgaaaca gctgatttat ttatggctgt
    22681 cattatgtat cgtttgaaag aaaatggtcg tgttggagtt attttacctg atggttttct
    22741 atttggtgaa ggtgtaaaaa ctcgcttgaa acaaaaactg gtagatgagt tcaacttgca
    22801 tacgattatt aggttgcctc atagtgtctt tgcaccgtat acaggaatcc atacgaacat
    22861 tcttttcttt gataaaacaa agaaaacaga agaaacttgg ttttatcgtt tagatatgcc
    22921 agatggttat aaaaatttct cgaaaactaa gccgatgaag tcagaacact tcaatcctgt
    22981 tcgtgactgg tgggaaaatc gtgaagagat tctggaaggt aagttctaca aatctaaatc
    23041 atttacacct agtgaattgg ctgagttgaa ttataattta gaccagtgtg gttttccaaa
    23101 agaggaagag gaaatcttaa atccctttga gttgattcag aattatcaag cggaaagagc
    23161 aactttaaat cataagattg ataatgtatt agctgatatt ttgcagttgt tggaggacaa
    23221 ataatgacac cagaacaact taaggcaagt attctccaaa gagcgatgga agggaaatta
    23281 gtgccgcaaa atcccaatga cgaacctgca agtgaattat taaagagaat taaagctgaa
    23341 aaagaaaaac ttatcagtga aggaaaaatc aaacgagata aaaaggaaac tgagatattt
    23401 cgtggtgatg atgggaaaca ttatgggaag tttgctgatg gaagcactca agaaattgat
    23461 gttccttatg atattcctga tacttgggag tgggtgagga taaaatcaat ttattggaat
    23521 tttgggcaaa ataagccaga gaaatccttt aggtatatag atacgtctag tattgataga
    23581 aaaaagaaca taatcaacta caaaaatcta caatatcttt cacctgaaca agcgccttcc
    23641 cgtgctagaa aattagtttc gcagaatagt gtcttatttt caacagttag accatatcta
    23701 aaaaatattg ctgtagttag agaacttaaa gagtatttga tagctagtac agcatttatt
    23761 gttttggata ctttacttaa cgaaacatat ttgaaatatt atttattatc agataatttt
    23821 atcaatcgtg ttaataataa atctactgga acaagttatc ctgcaatcaa tgattataat
    23881 tttaatctat tattaattgc tctcccccca ctatccgaac aacaacgaat agtagaagca
    23941 atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa gttataatag actagaacag
    24001 ctagataaa
//
LOCUS       DBEROT010000034        22744 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.34, whole genome shotgun sequence.
ACCESSION   DBEROT010000034 DBEROT010000000
VERSION     DBEROT010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22744
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.34"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            138..392
                     /gene="blpM"
                     /locus_tag="ACL8CG_001564"
     CDS             138..392
                     /gene="blpM"
                     /locus_tag="ACL8CG_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HGS1344129.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            408..611
                     /gene="blpN"
                     /locus_tag="ACL8CG_001565"
     CDS             408..611
                     /gene="blpN"
                     /locus_tag="ACL8CG_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HGS1344130.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            855..1004
                     /gene="blpO"
                     /locus_tag="ACL8CG_001566"
     CDS             855..1004
                     /gene="blpO"
                     /locus_tag="ACL8CG_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGS1344131.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1108..1227
                     /locus_tag="ACL8CG_001567"
     CDS             1108..1227
                     /locus_tag="ACL8CG_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS1344132.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1737..1930
                     /locus_tag="ACL8CG_001568"
                     /pseudo
     CDS             1737..1930
                     /locus_tag="ACL8CG_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2013..2411
                     /locus_tag="ACL8CG_001569"
     CDS             2013..2411
                     /locus_tag="ACL8CG_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGS1344133.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            2449..3138
                     /locus_tag="ACL8CG_001570"
     CDS             2449..3138
                     /locus_tag="ACL8CG_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1344134.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3180..3413
                     /gene="blpZ"
                     /locus_tag="ACL8CG_001571"
     CDS             3180..3413
                     /gene="blpZ"
                     /locus_tag="ACL8CG_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGS1344135.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLSSDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3564..4175
                     /locus_tag="ACL8CG_001572"
     CDS             3564..4175
                     /locus_tag="ACL8CG_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1344136.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4336..5130
                     /gene="ccrZ"
                     /locus_tag="ACL8CG_001573"
     CDS             4336..5130
                     /gene="ccrZ"
                     /locus_tag="ACL8CG_001573"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGS1344137.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5127..5762
                     /gene="trmB"
                     /locus_tag="ACL8CG_001574"
     CDS             5127..5762
                     /gene="trmB"
                     /locus_tag="ACL8CG_001574"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGS1344138.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            5888..6367
                     /gene="rimP"
                     /locus_tag="ACL8CG_001575"
     CDS             5888..6367
                     /gene="rimP"
                     /locus_tag="ACL8CG_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGS1344139.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6411..7547
                     /gene="nusA"
                     /locus_tag="ACL8CG_001576"
     CDS             6411..7547
                     /gene="nusA"
                     /locus_tag="ACL8CG_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGS1344140.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7569..7862
                     /locus_tag="ACL8CG_001577"
     CDS             7569..7862
                     /locus_tag="ACL8CG_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGS1344141.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7855..8154
                     /locus_tag="ACL8CG_001578"
     CDS             7855..8154
                     /locus_tag="ACL8CG_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGS1344142.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8171..10963
                     /gene="infB"
                     /locus_tag="ACL8CG_001579"
     CDS             8171..10963
                     /gene="infB"
                     /locus_tag="ACL8CG_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGS1344143.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11214..11564
                     /gene="rbfA"
                     /locus_tag="ACL8CG_001580"
     CDS             11214..11564
                     /gene="rbfA"
                     /locus_tag="ACL8CG_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGS1344144.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            11843..12622
                     /locus_tag="ACL8CG_001581"
     CDS             11843..12622
                     /locus_tag="ACL8CG_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344145.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYLILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            12624..12806
                     /locus_tag="ACL8CG_001582"
     CDS             12624..12806
                     /locus_tag="ACL8CG_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344146.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            13221..13454
                     /locus_tag="ACL8CG_001583"
     CDS             13221..13454
                     /locus_tag="ACL8CG_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGS1344147.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            13454..14788
                     /locus_tag="ACL8CG_001584"
     CDS             13454..14788
                     /locus_tag="ACL8CG_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGS1344148.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEVFEAFAIEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            14798..15052
                     /locus_tag="ACL8CG_001585"
     CDS             14798..15052
                     /locus_tag="ACL8CG_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGS1344149.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            15148..15543
                     /locus_tag="ACL8CG_001586"
     CDS             15148..15543
                     /locus_tag="ACL8CG_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS1344150.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            15827..16390
                     /locus_tag="ACL8CG_001587"
                     /pseudo
     CDS             15827..16390
                     /locus_tag="ACL8CG_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            16393..16953
                     /locus_tag="ACL8CG_001588"
     CDS             16393..16953
                     /locus_tag="ACL8CG_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1344151.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEVI"
     gene            16953..17531
                     /locus_tag="ACL8CG_001589"
     CDS             16953..17531
                     /locus_tag="ACL8CG_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1344152.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGVTFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            17524..20175
                     /locus_tag="ACL8CG_001590"
     CDS             17524..20175
                     /locus_tag="ACL8CG_001590"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGS1344153.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDARFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTINPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            20245..21000
                     /locus_tag="ACL8CG_001591"
     CDS             20245..21000
                     /locus_tag="ACL8CG_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGS1344154.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            21277..22080
                     /locus_tag="ACL8CG_001592"
     CDS             21277..22080
                     /locus_tag="ACL8CG_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGS1344155.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYENATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(22196..22744)
                     /locus_tag="ACL8CG_001593"
                     /pseudo
     CDS             complement(22196..22744)
                     /locus_tag="ACL8CG_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         6912 a         4087 c         5097 g         6648 t
ORIGIN      
        1 tctaatgtaa tttttgcaat tcaagacgtt tcgatgacta ttcaagatct ggatgaaaaa
       61 ttttaaaaaa cgatgatata ctaaacttgt caaagttaca acaagacaaa aattaaaaat
      121 aaaaaagagt atttgtcatg gatacaaaaa ttatggaaca atttcatgaa atggatataa
      181 ctatgttatc tagtattgaa ggaggcaaga ataattggca aactaatgtc ttagaaggtg
      241 gtggtgctgc ttttggtggc tgggggctag ggacagctat ttgtgctgcg agtggtgttg
      301 gagcaccatt tatgggagca tgtggataca taggagctaa atttggtgtg gatctttggg
      361 caggagtaac aggggcaacg ggtggatttt aataaaagga gacttgtatg aatacttatt
      421 gtaatataaa tgaaacaatg ctgagtgagg tttatggagg taattccgga ggagcagctg
      481 tagttgctgc tttaggttgt gcagcgggtg gagtgaaata tgggagactt ctaggaccat
      541 ggggcgctgc aataggagga attggaggag cagtggtttg tggatattta gcctataccg
      601 ctacatcata aaaatgaaag ctaaatttta tgaaggctat attctttatt attctcttcg
      661 cttttcaaac ctatcttatt tatctatcca taagtatctc cgataaaaaa caaaagacta
      721 ttgaattaac atcattgaat tgttttgtca tattatttct aatctatgat aaattaattt
      781 ttctctttat tgcctatgtt tttttgataa tttttatatt aaacttgttc cgtaactgaa
      841 aagtgatata ctatatggat acaaaaatga tgtcacaatt tgcagttatg gataatgaaa
      901 tgcttgcttg cgttgaaggt ggagatattg attggggaag aaaaattagt tgtgcagcag
      961 gggttgcata tggcgcaatt gatgggtgtg caacaacggt ttgacatttc tattgggaac
     1021 atttgctata ggaataggtg taactggtgc tgcaggtgga gctatacttg gaggtgtagc
     1081 ctatgcagca atatgttggt ggtaattatg gattttaaaa gttttattat tggtttagta
     1141 gttggtatat ttggtcctta tatggatgac ttaattagaa aaatattttc aaaatcttcc
     1201 aaaaaggata cggatagtac tctctaaaaa ataaatttct cccctgtatt tgctagctta
     1261 atttacaggg gagtttcttt aatattgttt cgcctgtcaa aatgatatgt gatagcagga
     1321 tgaaaagtct acaaacaagt tggtatcaat acaatataaa gaggaaagta tgtttttaat
     1381 gcttactttt taaatttttt aacaattcaa gatgtttcga tgacaattca agatttggat
     1441 gaaaaatttt aaaaaacaat gatatactaa acttgtcaaa gttgcaacgg gtgctgctac
     1501 attatgttaa aaatcgctct tgattgataa gttggatttg ttaggaaagg agtaaataat
     1561 tatggataag aaaaagatag tttcgactat aatatgtata gtatttcttg tagtgtcagt
     1621 agataatttt tttagagact taaccccgtt actgttcatt ttaaatatta ttggcctgtc
     1681 ttgcttttca gtgctaacat acattaacat aaaagagata ctcttaaata taagtaaatg
     1741 atgatttggt tagtcctaga accaatcaac ttatgtttat cggcttggca gattttatgt
     1801 ttgtcatttg tttgtataga ggtatttcag aaacagaatt ctatcaacaa ctaatcgctt
     1861 atataggtgt attctctgct tgtttagcac gcttctgctc atgtggggct tgaagtatta
     1921 taaaaagtag ctttctatcc ttttctgaca ggatatttga gtagaaggct ctattaaatt
     1981 gttagtgaaa taaatgaatg gaggtattta atatgaaata cagattattt tttgttattt
     2041 tcttgagtag tgtgttggat attcttttag ggacattttt acaaatctct atcgtatcta
     2101 ttgggtggct tgttctttac agtggtttgt ttgaagcagg agttttcctt cttgctaata
     2161 aaggggtggc ggtaaaaatc aaggaagtag atattcgaaa tcgctttaaa tttatttttg
     2221 gaaaaacctt atggtttcaa attcttttgc tcatcttttt gataatcaaa ctttatcttg
     2281 gtttggatgc gaggttgatt ttattctatg gacatatttt cattgtcttt aatgccttaa
     2341 tgtatctatt atctagtagt caggttagcc ttaaaaaaaa acaaactgtc ttcttaatct
     2401 tacagcagta gagcctgaca aggtgaggtc atagtaggga ggatttctat gaaaaagtat
     2461 caacttctat tcaaaataag tgcagtcttc tcttacttat ttttcgtatt tggtctttct
     2521 cagctgacgc ttatcgtcca aaactattgg caattttctt cccagattgg caatttcgtc
     2581 tggattcaaa atatcttgag tttacttttt attggagtca tgattgtggt tcttgttaag
     2641 acaggccatg gttatctctt ccgcattcca agaaaaaaat ggctttggta ttcgattttg
     2701 acagtattag tggtagtgtt ccagatctct tttaacgttc agacagctaa acatgttcag
     2761 tcaactgcgg aaggttgggc tgtattgatt ggttatagtg ggactaactt tgcagagcta
     2821 ggtatttata tagccctgtt ctttctggtt ccactgatgg aagaattgat ttatagagga
     2881 ttactgcaac atgctttctt taagcattcg cgatttggtc ttgatttgct tcttccttct
     2941 attttatttg ctctccctca tttttcaagc ctgcctagtc tgttagatat cttcgtcttt
     3001 gcaacagttg gaatcatctt tgctggtttg acccgctata ccaagagcat ttatccatcc
     3061 tatgcggtgc atgtgatcaa taatattgta gcgaccttcc cgtttttgct cacttttcta
     3121 catagggtct tggggtaaaa aaacaaaagg cttgcttttc agccatagag gaggtcatca
     3181 tgtataaaca cttatttttc ctagattcca aaactttaga tcggttgaca ccctatattc
     3241 tagtcttgtc ttctgacacc attgctttta atgtttttgt gctaaccttt gtatctgcgg
     3301 tggtttttaa tttcctaaat tccatgctag ctttaatggc tatattcata ggggctggct
     3361 atgtggtcgg attttggtta ctaatactca atgaaaatca aagagcaaac taggaaacta
     3421 gccgcaggct gtacttgagt acggcaaggc gacgttgacg tggtttgaat ttgattttcg
     3481 aagagtataa aatggtttgt tttggaaagg ctagaactaa agaatgacgt gtaggaagtc
     3541 tgtttgttga ggaggataat tttatggagt tttttgataa atttcatgcc ttgtgttttg
     3601 gatttttagt actaataatt gtcattacag ttccttatac gattaaccat gggggttttt
     3661 ttcaaaatga atctgcattg attcttgtaa gtcttcttgt aacctcgctg agtgttgctt
     3721 atgctagaaa gtttgaaatg atttcttttg ggatgttaag caagaaacaa cttttgcttt
     3781 tcattgcaat ctttcttcta agtgtacttg agacgctggt ttatattcat ttcttcgctg
     3841 tttcttctgg ctcaggggtc caacacttgg cggaagtcag cagaggaatt tccctgtctt
     3901 tgattttaac tacctcagtt tttggcccca tccaggagga actcattttc agaggacttc
     3961 ttcaaggtgc ggtttttgac aattcttggt tagggcttgt gctaacttcc tctctctttt
     4021 ctttcatgca tggaccttct aatgtccctt cgtttatttt ttatctactt gggggtttgt
     4081 tgctgggctt tgcttataaa aagagtcaaa acctatgggt ttctactcta gtccatatgc
     4141 tttacaacag ttggccactc ttatattatt tataaaaatt atgaaaaggt aagcagaaga
     4201 cggtgcttac ctttttcaag ctataatgat acccaagcca atccagaggc ttttctttga
     4261 gaatcgggtt agagtggttg acgaataggc caaaaactag tagaatagta aggaaacttt
     4321 atacggagga aagaaatgga tttgggtgat aatgagctaa cactgactcc catacctggg
     4381 aaaagtggca aggcttatat gggtagctat cctgatggga agcgcatctt tgtaaaaatg
     4441 aacacctctc caatcctacc tggtctagct agagaacaaa ttgctccaca attattatgg
     4501 agtcgtcgtt tggcagatgg gcgtgatatg tgtgctcaag aatggttgac aggcaagata
     4561 ttgaccccct atgatatgaa tcgtaagcaa atcgtcaata ttttaacccg tcttcatcgc
     4621 tcacgtccgt tgatgacaca attgagtcgt ttgggctatg ccatggaaac acctgtagat
     4681 ttactacagt cttggcagga aacggctcca gatgctttgc gtaaaaatca ttttatcagt
     4741 gaagtgatgg ctgatttacg tcagactatt ccaggattta gagaggacca tgcgaccatt
     4801 gtccatggag atgtacgaca tagtaattgg attgagacag atagtggctt gatttattta
     4861 gtagattggg attcggttcg cttgaccgat cgcatgtttg atgtggccca tatgctctgc
     4921 cattatattt cagaacatca gtggaaggaa tggttgacct actacggtta caagtacaat
     4981 caaacggtat taagtaaatt gtattggtat ggtcaattgt cttatttgag tcagatttcc
     5041 aagtattata tgaaccaaga tttagaaaat gtcaatcggg agattcatgg tttgcgtcat
     5101 ttccgagaca agtatggaaa gagaagatga gagttagaaa tcgtaaaggg gcaacagaat
     5161 tactagaggc aaatccccag tatgtggtcc tcaatccctt ggaagccaag gcaaaatggc
     5221 gggacttgtt tggcaatgat aatcccattc atgtggaagt tggaagtgga aagggtgcct
     5281 ttgtttcagg tatggccaag caaaaccctg acatcaacta tatcgggatt gatattcaaa
     5341 agtctgtttt gagctacgct ttggacaagg tgcttgaagc tggagtgtct aacatcaagc
     5401 tcttgtgggt agatggttct gacttgactg actactttga agacggtgag attgatcgct
     5461 tgtatctgaa cttttcagat ccatggccga aaaaacgcca tgaaaagcgt cgtttgacct
     5521 acaagacctt tttggatacc ttcaaacgta tcttgcctga aaatggagaa attcatttca
     5581 agacggataa ccgtggcttg tttgagtaca gtttagtgag cttttctcaa tatggcatga
     5641 aactcaatgg tgtctggcta gatttgcatg ccagtgattt tgaaggcaat gtcatgacag
     5701 aatacgagca aaaattctca aacaaggggc aagttatcta ccgagttgag gcagaatttt
     5761 aagagatagc ctaaaattag gctgtacaag tgcttttgct ttacataagt tggcaaacgt
     5821 gctatactga tagtaagaat atgaaaagtg aggcggggaa atatcttcgc ctcttgctta
     5881 tgaggaggtg gacgcaatcg caacaatcgt agaattagtc agagaagttg tagaacctgt
     5941 catagaagct ccttttgaac tcgtggatat cgagtatgga aagattggca gtgacatgat
     6001 tctcagtatt tttgtagata aacccgaagg aattaccttg aacgacacgg cagacttgac
     6061 agaaatgatc agtcctgtcc tagacaccat caagccagat cccttcccag aacaatattt
     6121 cctagaaatt accagtccag gtttggaacg tcctttgaaa accaaggatg ccgtcgctgg
     6181 agcggttgga aaatacatcc atgtcgggct ctaccaagcc atcgataagc aaaaggtctt
     6241 tgaaggaacc ttgttggcct tcgaagagga cgagttgact atggaatata tggacaagac
     6301 gcgtaagaaa accgtccaaa ttccatacag tttagtatca aaagcacgtt tagcagttaa
     6361 attatagaaa aagaaaggat agcttttgag gattcaaaag tgaagaaaac atgagtaaag
     6421 aaatgctaga ggccttccgc attttggaag aagacaaggg aatcaaaaaa gaagatatca
     6481 tcgacgcagt agtagagtcg cttcgttccg cttatcgcag acgctatggt cagtcagaca
     6541 gcgtagctat tgacttcaac gaaaaaacag gtgactttac agtttatact gtccgtgaag
     6601 ttgttgatga agtatttgat agccgtttgg aaatcagctt gaaagatgct cttgccatta
     6661 attcagctta tgaacttgga gacaaaatca agtttgaaga agcaccagct gagtttggtc
     6721 gtgtagcagc ccaatctgcc aaacaaacca tcatggaaaa aatgcgcaag caaacacgtg
     6781 ccatcactta caatacttac aaagaacatg agcaagaaat catgtctggt acagtagaac
     6841 gctttgacaa ccgctttatc tatgtcaacc ttggtagcat cgaagcccaa ttgtcaaaac
     6901 aagaccaaat tcctggagaa gtttttgctt ctcatgatcg tatcgaagtt tatgtttaca
     6961 aggttgaaga caaccctcgt ggtgtgaacg tctttgttag ccgtagccat ccagaaatga
     7021 tcaaacgttt gatggagcaa gaaattccag aagtttatga tggaactgtt gaaatcatga
     7081 gcgtggctcg tgaagcaggt gaccgtacga aggttgctgt tcgtagtcac aatccaaacg
     7141 tggatgctat cggtacaatc gttggacgtg gtggtgctaa tatcaagaag attactagca
     7201 aattccaccc agctcgttac gatgctaaaa atgaccgcat ggtaccaatc gaagaaaata
     7261 tcgatgttat cgagtgggta gcagatccag ctgaatttat ctacaatgcc atcgctcctg
     7321 ctgaggttga ccaagttatc tttgatgaaa acgacagcaa acgtgccttg gtggttgttc
     7381 cagataacaa gctttctctt gccattggtc gtcgtggaca aaacgtgcgc ttggcggctc
     7441 acttgactgg ttaccgtatc gatatcaagt ctgctagcga atttgaagcc atggaagacg
     7501 ctgcttcagt agagttggaa gtagaaaacg atactgtaga agaataaaag ctgctagagg
     7561 agggaaagat gaaaacaaga aaaatccctt tgcgcaagtc tgttgtgtct aacgaagtga
     7621 ttgataagcg tgatttgctc cgcattgtca agaacaagga aggacaagtc tttattgatc
     7681 ctacgggcaa ggccaatggc cgcggcgctt atatcaaact agacaatgca gaagccctag
     7741 aggcgaaaaa gaagaaggtc tttaaccgca gctttagcat ggaagtggaa gaaagctttt
     7801 atgacgagtt gatcgcttat gtggatcaca aagtgaaaag aagagagttg ggacttgaat
     7861 aagcaaaaga taagtaatct cttggggctt gctcagcgag cagggcgcat catatcgggt
     7921 gaagaattgg tggtcaaggc cattcaagac ggcaaggcca agttggtctt tctagctcat
     7981 gatgctggac ccaatctggc caagaagatt caagataaaa gtcattatta tcaagtagaa
     8041 attgtaaccg tgttttcaac actggaatta agcatagcag tcgggaaatc gagaaaggtt
     8101 ttggctgtaa cagatgctgg atttacaaag aaaatgaggt ctcttatgga atagaagagg
     8161 aggacgtgat ttgtctaaga aaagattgta cgaaatcgca aaagaacttg gaaaagaaag
     8221 taaagaagtt gtagcgcgtg caaaagagtt gggcttggat gtgaaaagcc actcatcaag
     8281 tgtggaagaa gctgtcgctg caaaaattgc tgccagcttt aagcctgcag ctgctccgaa
     8341 agtagaagca aaacctgcag caccaaaagt aagtgcagaa aagaaagccg aaaaatctga
     8401 gccagctaaa ccagctgtag ctaaggaaga ggcaaaaccg gctgagccag ttgctccgaa
     8461 aacagaaaaa gtagcagcga aaccgcaaag tcgtaatttc aaggctgagc gtgaagcccg
     8521 tgctaaagag caggcagaac gacgcaagca aaataagggc aataaccgtg accaacaaca
     8581 aaacggaaac cgtcagaaaa acgacggccg taatggtgga aaacaaggtc aaagcaaccg
     8641 cgacaatcgt cgctttaatg accaagctaa gaagcagcaa ggtcagcaaa aacgtagaaa
     8701 tgagcgccgt cagcaagagg ataaacgttc aaatcaagcg gctccacgta ttgactttaa
     8761 agcccgtgca gcagccctaa aagcagagca aaatgcagag tacgctcgtt caagtgagga
     8821 acgcttcaag cagtatcagg ctgctaaaga agccttggct caagctaaca aacgcaagga
     8881 accagaggaa atctttgaag aagcggctaa gttagctgaa caagcacagc aagttcaagc
     8941 agtggttgaa gtcgtccctg agaaaaaaga acctgcagtg gatacacgtc gtaaaaaaca
     9001 agctcgacca gacaaaaatc gtgacgatta tgatcatgaa gaagatggtc ctagaaaaca
     9061 acaaaagaat cgaagtagtc aaaatcaagt gagaaatcaa aagaatagta actggaataa
     9121 caacaaaaag aacaaaaaag gcaataacaa gaacaaccgt aatcagactc caaaacctgt
     9181 tacggagcgt aaattccatg aattgccaac agaatttgaa tatacagatg gtatgaccgt
     9241 tgcggaaatc gcaaaacgta tcaaacgtga accagctgaa attgttaaga aacttttcat
     9301 gatgggtgtc atggccacac aaaaccaatc cttggatggg gaaacaattg aactcctcat
     9361 ggtggattac ggtatcgaag caaaacaaaa ggttgaagtg gataatgctg acatcgaacg
     9421 tttctttgtc gaagatggtt atctcaatga agatgaattg gttgagcgtc caccagttgt
     9481 tactatcatg ggacacgttg accacggtaa aacaaccctt ttggatactc ttcgtaactc
     9541 acgtgttgcg acaggtgaag caggtggtat tactcagcat atcggtgcct accaaatcgt
     9601 ggaaaatggt aagaagatta ccttccttga tacaccagga cacgcggcct ttacatcaat
     9661 gcgtgcgcgt ggtgcttctg ttaccgatat tacgatcttg gtcgtagcgg cagatgacgg
     9721 ggttatgcct cagactatcg aagccattaa ccactcaaaa gcggccaacg ttccaatcat
     9781 cgtagccatt aacaagattg ataaaccagg tgctaaccca gaacgcgtta tcggtgaatt
     9841 ggcagagcat ggagttatgt caactgcttg gggtggagat tctgaatttg ttgaaatctc
     9901 agctaaattc aaccaaaata tcgaagaatt gttggaaaca gtccttcttg tagctgaaat
     9961 ccaagaactc aaggcagacc caacagtgcg tgcaatcggt acggttatcg aagcgcgctt
    10021 ggataaagga aaaggtgcgg tcgcaaccct tcttgtacaa caaggtacct tgaatgttca
    10081 agacccaatc gttgtcggaa ataccttcgg tcgtgtccgt gctatgacca acgaccttgg
    10141 tcgtcgtgtt aaagttgctg gaccatcaac accagtctct atcacaggtt tgaacgaagc
    10201 accgatggcg ggtgaccact ttgccgttta cgaggatgaa aaatctgcgc gtgcagcagg
    10261 tgaagagcgt gccaaacgtg ccctcatgaa acaacgtcaa gctacccaac gtgttagcct
    10321 tgaaaacctc tttgataccc ttaaagctgg ggaactcaaa tctgttaatg ttatcatcaa
    10381 ggctgatgta caaggttctg ttgaagccct ttctgcctca cttcaaaaga ttgacgtgga
    10441 aggcgtcaaa gtgactatcg tccactcagc ggtcggtgct atcaacgaat cagacgtgac
    10501 ccttgccgaa gcttcaaatg cctttatcgt tggtttcaac gtacgcccta caccacaagc
    10561 tcgtcaacaa gcagaagctg acgatgtgga aatccgtctt cacagcatta tctacaaggt
    10621 tatcgaagag atggaagaag ctatgaaagg gatgcttgat ccagaatttg aagaaaaagt
    10681 tattggtgaa gcggttatcc gtgaaacctt caaggtgtct aaagtgggaa ctatcggtgg
    10741 atttatggtt atcaacggta aggttgcccg tgactctaaa gtccgtgtta tccgtgatgg
    10801 tgtcgttatc tatgatggtg aactcgcaag cttgaaacac tataaagacg acgttaagga
    10861 agttacaaac ggccgtgaag gtggattgat gatcgacggc tacaatgata ttaagatgga
    10921 tgatgtgatt gaggcgtatg tcatggaaga aatcaagaga taagattttt tgctcctttc
    10981 ttaggtggtg agggacgcaa gcaaaccgat ggtttcattg cttatttttg agcctagggt
    11041 ctcaaaaatc ccccgtgatg ggactgataa atcagttcca tcactttcac cacggcgaaa
    11101 gaagcagatg acttcaaatt gaacttcgtt tcaatttaaa ctgaaaatca agaagtttaa
    11161 aatagctagg tctgctggcc tagcttttgg ttcaaagtag agaaaggaat atcatggcaa
    11221 atcatttccg tacagatcgt gtgggcatgg aaatcaagcg tgaagtcaat gagattttgc
    11281 aaaagaaagt ccgtgatcca cgtgtccaag gtgtgaccat cacagatgtt cagatgctgg
    11341 gtgacttgtc tgttgccaag gtttattaca ccattttgag taaccttgct tcggataacc
    11401 aaaaagccca aatcgggctt gaaaaagcaa ctggtaccat caaacgtgaa cttggtcgca
    11461 atttgaaatt gtacaaaatc ccagatttga ccttcgtcaa agacgagtcc atcgagtatg
    11521 gaaacaagat tgacgagatg ctacgcaatc tggataagaa ctaaagaaga ggggttgccc
    11581 ctcttttttg gtggaggaaa ataggttgaa tttgaaatgg aaaaatattc ttttataata
    11641 gattgaaact agaatagtac gcctctactt ctaaaatatt gttagaaatc gatttgactg
    11701 tcctgatcga tttgtcctgt tcttgtttca ttttactata aaaaaggggt tctgtatttt
    11761 ttaatgttat ctaattagaa aatgcttttt ttgtaggaaa tataatatga taaggtgtaa
    11821 aaaagaaata aggagtttgt atatggctga acaagactta gctatgcaag tattacaaca
    11881 agtggtaaaa ctaccagttg ttaaggttga tcgttcgaaa tttttagtgg ataagttttc
    11941 caaagaattg ggtccacagg acattcctac cttattggaa caaggtccaa cgtctctctt
    12001 atctcaagaa atcttagatc gagtggctaa tgcctgtatt agggataatg ttttattagc
    12061 gagtgggact tctgttttgg caggattacc tggagggctt gctatggcaa ttaccattcc
    12121 agctgatgtg gctcaatttt atggtttctc tctgaaattg gcccaagaat taggttatat
    12181 ttatggttat gaggatcttt gggcttcacg cgatgagttg agtgaagatg ctcaaaatac
    12241 ccttttgctt tatctaggcg tcatgttggg ggtgaatgga actgctgctt tgctacgtgc
    12301 tggtggtata acaattgcca aacaggtaat gaaaacagta cctaataaag ctttaacaaa
    12361 gacgctttgg tatcttattt tgaaaaaagt tttaagaata tttggtgtga atcttaccaa
    12421 gggagggctg gccaaaggaa tggggaaatt tattcctatc ttgggtggta tcatttcagg
    12481 tggtttaacc tttgcaacta tgaaaccgat gggtgaaagc ttgcagaaag aattgtccaa
    12541 gctagttaac tatagtgaag ttcaatatca agaagatgtt gaaacaatcc gaaaagaggc
    12601 tgaaatcatc gaaggagagt aatatgggac tcataaaaac tctagctaaa atttatggta
    12661 attacttttt gaccgtgcaa ggtgtaaaag tgatgaaaac gataaagaaa gatgaccatg
    12721 tcgttgttgg tctgggaaaa ctctttattg cagataagct aatggatacg gctcggtggc
    12781 tcattaagcc agaggagaga gaatgaaatt tttttggtct tcttgctatt ctttttatca
    12841 aaccgattat tgagattgtg aaattctttt ggatgatcat ttcttttgca gtccaattgc
    12901 tgttttacaa gatattattt aagatattgg attggctctt taaacttatc tagatggtaa
    12961 tccaagtcgc agagaactag caggaactcc actgctagtt ttttattctc tttccatatg
    13021 gtataatata agcagtaaaa tcattttata ctcttcgaaa atctcttcaa accacgtcag
    13081 cttcaccttg ctgtatatat gttactgact tcgtcagttc tatccacaac ctcaaaacac
    13141 tgttttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtattag
    13201 aacatacaat ggaggtcgtc atggacaata tcatcgatgt gtcaattcct gttgcagaag
    13261 tggtggacaa gcatccagaa gtcttggaaa ttctagtgga gttgggtttt aaaccccttg
    13321 ccaatccctt aatgcgcaat acagttggtc gtaaagtatc acttaaacag ggttctaagc
    13381 tagcaggaac tcctatggac aagattgtac gcacactgga agcgaatggc tacgaagtga
    13441 ttggattaga ctaatggcag atgaacggat tcatgtccta cgggatattt tattagaatt
    13501 gcataatggc gcctctcctg agtcggttca ggagcgtttt gatgcgacct ttgcgggtgt
    13561 ctcagccatt gagatttccc ttatggagca cgagcttatg aactcagact caggtgtcac
    13621 ctttgaagat gttatggaac tctgtgatgt ccatgccaat ctttttaaaa atgctatcaa
    13681 aggtgtcgaa gtttcagata ctgagcatcc aggtcaccca gttcgtgtct ttaaggaaga
    13741 aaatttggcc ctccgtgcag ctttgattcg cattcgtaga ttgttagata cctatgagtt
    13801 gatggaagac gaggaaatgc ttgcggagat gcgcaagggc ttggtgcgtc agatgggact
    13861 tgtggggcaa tttgacatcc attaccaacg taaagaagaa ctcttctttc ctatcatgga
    13921 gcgctatgga cacgattcac ctcccaaagt tatgtgggga gtggatgatc agattaggga
    13981 actctttcaa acagctctaa cgacagccaa gtcactacca gaagtgtcaa ttagcagtgt
    14041 aaaggaagtt tttgaagctt ttgcgataga gtttgaaagt atgattttca aggaagagtc
    14101 catcctcctc atgattctcc ttgagtcttt tactcaggat gactggcttc agattgcgga
    14161 ggagagcgat gcctatggct atgccatcat ccgtccgtca gagaaatggg tgccagaacg
    14221 acagagcttt attgaggaaa agattgcaga ggagcctgta cagctagata cggcagaagg
    14281 tcaagttcaa caagttatag atacgccaga aggccatttt accattacct ttacccctaa
    14341 ggaaaaggaa gctgtgctgg accgccatag tcaacaggct tttggtaatg gctatctttc
    14401 agtcgagcag gccaatctca tcctcaatca tctccctatg gagattacct ttgtcaataa
    14461 agaagatatt ttccagtatt acaatgacaa tacgccagct gatgagatga ttttcaaacg
    14521 gacgccgtcc caagtcgggc gcaatgtcga actctgtcat ccgcctaagt atttggacaa
    14581 ggtcaaggct atcatgaagg gacttcgtga ggggaccaag gacaagtatg aaatgtggtt
    14641 caagtctgag tcgcgaggca agtttgtcca catcacctat gctgcagtac acgatgaaaa
    14701 cggagaattc caaggtgtac tggaatacgt tcaggatatc cagccctacc gtgagattga
    14761 tacggactat tttcgtggat tagaataagg agaaaaaatg agttacgaac aagaatttat
    14821 gaaggaattt gaagcttggg tcaataccca aatcatgatt aacgacatgg cgcacaagga
    14881 aagccaaaaa gtttacgaag aagaccagga cgagcgtgcc aaagatgcca tgattcgcta
    14941 cgagagtcgc ttggatgctt atcagttctt gcttggtaag tttgaaaact tcaaagcagg
    15001 caagggattc catgatttgc cagaaggctt gtttggtgag cgaaattatt aaacgagaaa
    15061 gattcttgat ttttcactaa aatcttgata gaatgtttat gttaaatcct tgtcagagca
    15121 gggatttttt attgaaagga ttttatcatg tcaaagaaac tcaatcgtaa aaaacaatta
    15181 cgaaatggcc tccgtcgcgc aggtgccttt tcaagtactg tgactaaggt tgtagatgag
    15241 acaaaaaaag tcgtgaagcg tgcagaacag tcagcaagcg cagctggtaa ggcagtttct
    15301 aaaaaagttg aacaagcagt agaagctacc aaagagcaag ctcaaaaagt agctaattct
    15361 gtagaagatt ttgcagcaaa cttgggtgga cttccacttg atcgtgccaa gactttctat
    15421 gatgaaggaa tcaagtctgc ttcagatttc aaaaactgga ctgaaaaaga actccttgcc
    15481 ttgaaaggaa tcggcccagc taccatcaag aaattgaaag aaaatggcat caagttcaag
    15541 taatttttct tgagccttgc atttccgaga aaaacttgct acaatagagc cattagaggt
    15601 gttttgaatc ccacatttta cagaaagtgg cggtgctgag aagtccacaa atgtgtcaaa
    15661 actggttgct aatggatgaa aaattgaaat aaaagtgtct ttttgcttta aagacgagag
    15721 ttgcgggcaa ctgcccgaaa ttgggtggta ccgcggataa atacattcgt ccctgtcatg
    15781 tagatggcag ggcttttctt ttgtgtctta gtcaaaggag gttgttataa aacaatcatt
    15841 taaaactaat aaactatatt atagttttcc tgtttttatt ttaggatatc aagatcagaa
    15901 ttttggctat aacattacga cctgtagttc ctcgtatagt ctaggagatt gggttgtaat
    15961 tggagtcgtt gcgagagaga atgccgcaga gcagatcaaa cagtatcaaa aatttactgt
    16021 gaatatttct gatgaaactt ctatgcttgc gatggagcag gctggtttta tcagtcatca
    16081 ggagaaattg gaacgtttgg gagtgcatta tgaaatttct gaacgaactc agactcctat
    16141 tttagacgcc tgtccacttg ttttagattg tcgggtagat aggattgttg aggaagacgg
    16201 tatttgccac atctttgcca agattcttga gcgacttgtt gccccagaac tcctggatga
    16261 aaagggacat tttaaaaatc aactgtttgc cccaacctat ttcatgggag atgtatatca
    16321 gcgcgtttat cgctatctgg acaagcgtgt agatatgaag ggcagtttca tcaaaaaaag
    16381 cgaggaagaa ggatggcaag aactgagctg ccagataaaa tcgaaacaga acgtctcgtt
    16441 ttacgagtcc gtactgtggc ggatgctgag gatatctttg actatgctag tttgccagag
    16501 gtcgcctatc cagcaggttt tcctccagtc aagaccttgg aagatgagat ttattatctg
    16561 gagcacattc ttccggagcg taatcaaaag gaaaatctcc cagcaggcta cgggattgtc
    16621 gtcaaaggaa cggataagat cgttggctct gtcgatttca accatcgcca tgaagatgat
    16681 gtgctggaaa tcggctatac cttacaccca gactattggg ggcgaggtta tgtgccagaa
    16741 gctgcgcgtg ccttgattga cttagccttt aaagatttgg gtcttcacaa gattgaacta
    16801 acttgctttg gatataacct tcaaagtaaa cgagtcgcgg aaaagcttgg ctttaccctc
    16861 gaagctcgca taagagaccg aaaggatgtt caaggaaacc gctgtgacag tctgatatat
    16921 ggcttgctga agagcgagtg ggaggtgatt tgatgcatct tttcatcatt ggtgctccag
    16981 catcaggaaa aatgaccatt ggtcaagaat tatctcgact gacggatgct accctatttt
    17041 ataaccatca agccattgat tttgcactag aaatctatca ggactataca gaggaaatgt
    17101 gggaatttgt tcgtggagtc actttttcat tccttggagc aagtgcaaga aatcagcgat
    17161 cagtaatttt aacagatgta attgattttt caaatcagta tcatctgata tatttaaagc
    17221 aaattcagaa tttgttggat gattatcatc aagagattct ttttgttgag ttggaaacaa
    17281 gtcttgaaga gtgcatacgt cgaaatcgaa cggagaatcg attaaagcac aaacccttaa
    17341 aacgacatat tgaggtatct gaaagagaaa ttttagagac cgctgaaaca cttcaattaa
    17401 attcccaata tcaaccgaat gagttgcacc actactttaa aataaataat acgaatttgt
    17461 ctgcagaaga agctgctaag cagattcaaa ataaaataaa caaaatagag aaaggacaca
    17521 cacatgtcta aagaactttc atctaaatac aatccagccg aggttgaggc tggtcgttac
    17581 caaaaatggc ttgatgctga tgttttcaag ccttcaggcg atcaaaaggc taagccttat
    17641 tcaatcgtta ttccaccacc aaacgttaca ggtaaacttc accttggtca cgcttgggat
    17701 acaactttgc aagatattat catccgtcaa aaacgcatgc aaggttttga taccctttgg
    17761 cttcctggga tggaccacgc agggattgcc actcaggcta aggtagagga gcgcttgcgt
    17821 ggtgagggca tttcccgcta tgaccttggt cgtgagtctt tcttgacgaa agtctgggaa
    17881 tggaaagacg aatatgccac tactatcaag gaacaatggg gcaagatggg gctctctgta
    17941 gactactctc gtgagcgttt cactcttgac gaaggtttgt caaaagctgt tcgtaaggtc
    18001 tttgtggacc tttacaagaa aggctggatc taccgtggtg agtttatcat caactgggac
    18061 ccagcagctc gcacagccct ttctgatatt gaggtgattc acaaggatgt cgaaggtgcc
    18121 ttctaccaca tgaactacat gctggaagat ggttcacgcg cccttgaagt tgctacaact
    18181 cgtcctgaga ctatgtttgg ggacgttgcg gttgcggtta atccagaaga cccgcgctac
    18241 aaggacttga ttggtaaaaa cgtcatcctt ccaatcgcta ataaactcat cccaatcgtt
    18301 ggagatgagc acgcagatcc tgagtttggt actggtgtcg tgaaaatcac acctgcccac
    18361 gatccaaatg acttcttggt tggccaacgt cataacttgc cacaagtcaa cgtcatgaac
    18421 gacgacggaa ctatgaatga gcttgccttt gaattttcag gcatggatcg ttttgaagct
    18481 cgtaaggcag tcgttgctaa gttggaagaa atcggtgccc ttgtcaaaat cgaaaaacgt
    18541 gtccattcag tcggtcactc agaacgtaca ggtgtcgtag ttgagccacg cttgtctact
    18601 caatggttcg tcaagatgga ccaattggct aagaacgcca ttgccaacca agacacagag
    18661 gacaaggtcg aattctaccc acctcgtttc aacgatacct tccttcaatg gatggaaaat
    18721 gtccacgact gggttatctc tcgtcagctt tggtggggtc accaaatccc tgcttggtat
    18781 aatgaagcag gcgaaatcta tgtcggcgag gaagccccag cgggcgatgg ctggaaacag
    18841 gacgaagatg tccttgacac ttggttcagc tctgccctct ggcccttctc aaccatgggc
    18901 tggcctaata ccgaaactac tgactttaaa cgctactatc caaattcaac actcgtaaca
    18961 ggctatgata ttattccttt ctgggtatca cgcatgattt tccaaggaat tgaatttaca
    19021 ggaaagagcc catttaaaaa tgctcttatc catggtctaa ttcgtgatga agaaggacgt
    19081 aagatgtcta aatctcttgg aaatggcatt gacccaatgg atgttattga taaatatggt
    19141 acagatagtc ttcgttggtt cttgtcaaac ggctcagctc ctggtcaaga cgctcgtttc
    19201 tcttacgaga aaatggatgc ttcatggaac tttattaaca aaatttggaa catttctcgc
    19261 tatatcctca tgaacaatga aggtttgacg ctggatgtgg cgcatgacaa tgtcacaaaa
    19321 gttgcaacag gtgaggctgg taatgtgacg gaccgctgga ttctccacaa tctcaacgaa
    19381 accattgcaa aagttactga aaactttgat aagttcgagt ttggtgtggc tggtcatatc
    19441 ctttacaact tcatctggga agaatttgcc aactggtatg ttgagttgac caaggaagtc
    19501 ctttatagcg ataacgaaga agagaaagtc atcacacgtt ctgttctact atacactttg
    19561 gacaagatcc ttcgtctcct tcacccaatc atgccatttg tgacagagga aatctttgga
    19621 caaatctcag aaggatctat cgttacagca gaatacccaa ctatcaaccc agcctttgaa
    19681 gaccttgctg ctcacactgg tgtggaaagc cttaaagact tgatccgtgc cgttcgtaat
    19741 gcgcgtgcgg aagtaaacgt tgctccaagc aagcctatca ctatccttgt taagacaagc
    19801 gatagcgact tggaagcctt ctttaacagc aatgtcaact acatcaaacg tttcacaaat
    19861 cctgaacact tggaaatcgc atcaaccatc cctgcacctg aactggctat gtcaagcgtc
    19921 atcacaggag ccgaaatctt cttgccactg gtagacctct tgaatgtcga agaagaattg
    19981 gcacgtctgg aaaaagaact tgccaaatgg cagaaagaac tcgacatggt tggcaaaaaa
    20041 ctcagcaacg aacgcttcgt cgccaacgct aaaccagaag ttgtccaaaa agaacgcgac
    20101 aagcaagcag attaccaagc taagtatgat gcgaccgtag cacgtattga tgagatgaag
    20161 aagttggtga aataaacaca gaaacacggt gatgagccgt gttttttggt ataatgaaat
    20221 caatatctat tgatggagaa agtgatgtcc aaacaccctc attatgaatt gttaaattta
    20281 attggctacg gtcttgccaa gtttgacaag ctttttataa aagaatttca atgctctagc
    20341 aagtcggagt tttatcgcta tgtggtttct ctgggaattg ctgaaacaac tggagttgta
    20401 aaaaatagaa tggatttatt tgatccttat tttgacaata atcgaaaagg ttggtggcag
    20461 aaagctgaag tttatcgttt tcgtaaagat ttaattgata tgatgtttgg aaatgaagat
    20521 gttcatagtt atgctgaaat agttaaaatg ttacttgcca gtgaagggaa gaaaacaggc
    20581 ataaccatcg ttgaaaaacc aatagttcga actaaattca aacgtctaca ggaaacggga
    20641 atggaggctg agaattattt tatccttcat tttgataaag aagaaaaatt ccaaggtgga
    20701 cagttaaccg atgcccgtct ttatggtgat ggatatgact ttcaggtaga tgtccaagag
    20761 tattcttacc ttgccgaagt aaaaggtatc cgaaaatcta aggggcgtgt gcgtttaact
    20821 gcaaaagaat ttgaaaaagt caaggagttt caatcggatt ttattttatc cttggtcaca
    20881 aatctagatg atattccaaa gttagtgtta atcgataatc ctttaaaaca ttttgagttt
    20941 aaaaagaata ttatcaaaaa tgaaatcatt gaatatagaa gcgtagagga tttgtattag
    21001 ttccccctta acttttccag ttgaaggaac gagaagtctt gacaggtcaa cgacttaatg
    21061 aactggaaat caacggtatt cgtttgacta agttttaaga tggcgaaatc ggtattgaat
    21121 ttatcagtag tgctgattat aactctttta ttatttacat gaagtatata tatatatcat
    21181 agaacctatt gtgaggactt tttatagttt aagccagttt ccaaccaatt tcgtgattta
    21241 ctggtaatga agaaaaacaa ttgaaaggat atttctatgc aatcaactta caacattgac
    21301 aatccaaact tgtcttatga agcgaagcgt gatttatggc ggataggttt tggtctgcag
    21361 aaagttgaca atctagtgcc atcagcgtat atggaatctt tggctgagaa acagtcccgg
    21421 ggagaactga cttatgagca ggtttatgag aatgcaacgg cttatcacca tactattgat
    21481 gcaagtacgg aagaggcaga cttggtttct ctacgtattg tagaactatt gtctcgaaga
    21541 ggctttagct ttagtcctgc gaccttactt gctattcata aggagttgtt tcaagatata
    21601 tttgaaccct ctattccggt ggggcaattt cgtcagacca atatcacaaa gaatgaacct
    21661 gttttgaatg gtgaaagtgt tgtgtactct gattactcca tgattcaaat gaccttagat
    21721 tatgatttta atcaggaaaa acaagttgca tatgcgacac taactcaggc ggatgtggtt
    21781 aaacaaatcc agcattttat ttcaggaatc tggcagattc atccatttcg cgaaggaaac
    21841 actcggacag taacggtctt tttgattcag tatcttcgtg agtttggttt tgatattgat
    21901 aatacaccat ttcagcaaca ttccaaatat tttcgtgatg ccttggtatt agataatgca
    21961 aagattttac agcgacgttc tgagttttta acagcttttt ttgaaaatct cttgctcggt
    22021 ggtcaaaatg atttgtcttc agaaaaaatg tatctagatt tagacctcga tttttcataa
    22081 tccaaatact gagtaaacat tgaattttag gcaaaaatga agtaaatatt ctcacaagaa
    22141 aacgtatatc atcaaagttt taggtgtact gaccccaaaa agttagacaa ataatttatc
    22201 cgaaggattt agttctgtat tgcacaaggc taagtccttt tagttttacc ttaattcgtt
    22261 tattgttgta gtaatcaata tagtctacaa tagcttgttc caattgatta agtgatttaa
    22321 atgttttctc atagccataa aacatttccg atttcagaat cccaaagaag gactccatca
    22381 taccgttgtc ttggctgttt cccttgcgtg acatagatgc ttgaattccc ttactcttag
    22441 gaaccgatga taagaatcgt gtcggtattg ccagccttgg tcactatgga gaatcgtatt
    22501 ctcgtagtgc ttctctgtga atgcctgttc caacattgtt tgtacttgtt ctaagttggg
    22561 tgaagttgaa agattatagg cgataatttc gctgttaaag ccatctaaaa ctggtgataa
    22621 gtaaagcttt tgagtacttg ctggaatggc aaattctgtc acatctgtgt agcacttttc
    22681 cattgtttta gatccttcaa attggccttg aatgagattc tctgccttct taccaacgtc
    22741 tcct
//
LOCUS       DBEROT010000035        21738 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.35, whole genome shotgun sequence.
ACCESSION   DBEROT010000035 DBEROT010000000
VERSION     DBEROT010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.35"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(36..884)
                     /locus_tag="ACL8CG_001594"
     CDS             complement(36..884)
                     /locus_tag="ACL8CG_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGS1344156.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNHHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAS
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            1036..1314
                     /locus_tag="ACL8CG_001595"
     CDS             1036..1314
                     /locus_tag="ACL8CG_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGS1344157.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            1316..3379
                     /locus_tag="ACL8CG_001596"
     CDS             1316..3379
                     /locus_tag="ACL8CG_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS1344158.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3457..4713)
                     /gene="tyrS"
                     /locus_tag="ACL8CG_001597"
     CDS             complement(3457..4713)
                     /gene="tyrS"
                     /locus_tag="ACL8CG_001597"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGS1344159.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADTVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            4855..7317
                     /gene="pbp1b"
                     /locus_tag="ACL8CG_001598"
     CDS             4855..7317
                     /gene="pbp1b"
                     /locus_tag="ACL8CG_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGS1344160.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            7382..8293
                     /locus_tag="ACL8CG_001599"
     CDS             7382..8293
                     /locus_tag="ACL8CG_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1344161.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            8523..9221
                     /gene="dapD"
                     /locus_tag="ACL8CG_001600"
     CDS             8523..9221
                     /gene="dapD"
                     /locus_tag="ACL8CG_001600"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGS1344162.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            9289..10419
                     /locus_tag="ACL8CG_001601"
     CDS             9289..10419
                     /locus_tag="ACL8CG_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGS1344163.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            10431..10970
                     /locus_tag="ACL8CG_001602"
     CDS             10431..10970
                     /locus_tag="ACL8CG_001602"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGS1344164.1"
                     /translation="MKSELRKQVLQGMKAISQEQKQFIDQTLTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            10954..11631
                     /locus_tag="ACL8CG_001603"
     CDS             10954..11631
                     /locus_tag="ACL8CG_001603"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGS1344165.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(11698..12597)
                     /gene="galU"
                     /locus_tag="ACL8CG_001604"
     CDS             complement(11698..12597)
                     /gene="galU"
                     /locus_tag="ACL8CG_001604"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGS1344166.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKTVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(12619..13635)
                     /locus_tag="ACL8CG_001605"
     CDS             complement(12619..13635)
                     /locus_tag="ACL8CG_001605"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS1344167.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            13847..14287
                     /locus_tag="ACL8CG_001606"
     CDS             13847..14287
                     /locus_tag="ACL8CG_001606"
                     /inference="COORDINATES: protein motif:HMM:NF037495.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344168.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     ILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFAK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(14402..14833)
                     /locus_tag="ACL8CG_001607"
                     /pseudo
     CDS             complement(14402..14833)
                     /locus_tag="ACL8CG_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(14895..15545)
                     /gene="phoU"
                     /locus_tag="ACL8CG_001608"
     CDS             complement(14895..15545)
                     /gene="phoU"
                     /locus_tag="ACL8CG_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS1344169.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(15560..16312)
                     /gene="pstB"
                     /locus_tag="ACL8CG_001609"
     CDS             complement(15560..16312)
                     /gene="pstB"
                     /locus_tag="ACL8CG_001609"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1344170.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(16314..17129)
                     /gene="pstA"
                     /locus_tag="ACL8CG_001610"
     CDS             complement(16314..17129)
                     /gene="pstA"
                     /locus_tag="ACL8CG_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS1344171.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(17122..17985)
                     /gene="pstC"
                     /locus_tag="ACL8CG_001611"
     CDS             complement(17122..17985)
                     /gene="pstC"
                     /locus_tag="ACL8CG_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS1344172.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(18103..18978)
                     /locus_tag="ACL8CG_001612"
     CDS             complement(18103..18978)
                     /locus_tag="ACL8CG_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGS1344173.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTTKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(19145..20476)
                     /gene="pnpS"
                     /locus_tag="ACL8CG_001613"
     CDS             complement(19145..20476)
                     /gene="pnpS"
                     /locus_tag="ACL8CG_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGS1344174.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(20477..21184)
                     /locus_tag="ACL8CG_001614"
     CDS             complement(20477..21184)
                     /locus_tag="ACL8CG_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1344175.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(21268..21738)
                     /locus_tag="ACL8CG_001615"
                     /pseudo
     CDS             complement(21268..21738)
                     /locus_tag="ACL8CG_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="cupin domain-containing protein"
BASE COUNT         6301 a         4168 c         4718 g         6551 t
ORIGIN      
        1 tacggcaagg cgacgttgac gtggtttgaa gagtattaga atgctttccc aaccaaaatc
       61 tctgcttcga tggtaatctc tgtcagttgg ctccagtcaa tcttgctctg gtcaacgtga
      121 aagaggagag gagtcatact gagtagggct tggagttgtt ctgctgtgat agtcttagtc
      181 agagaggcag tttgactaga taggatggta aagtgttcct ggaaatgctc cttgatatct
      241 tggttagaat actccttgtt tgtcagctgg tcctgtactc tttgacggat ttctttgagg
      301 tgattttcag ttgggataac ctttatcaag ataccgtctt tggataaaac gcgacgaaat
      361 tctccatagt tggcaggtga gaagatatca agcaggatat ccatgctagc gtcttttata
      421 ggaaggcgtg ccaagtcgcc aacgaaccaa ttgactgccc agttgggttc acttttagca
      481 gcgatttgga ctgaatcttt ggagatgtca aaggcataga aagttttttc agagtgactt
      541 tcttgtagtt tgcgagaata gaatccttca ccacaaccga tatccaaaat tgttgtggta
      601 gtttttgagc ttgcaagcaa gtcagataca gcatctaaga tagcttggta aaagccggct
      661 tctaggattt gttgacggtt ttgaaaattt tccttgtcat agttagcaga ttgcttgatt
      721 tgaggtgcta gattgacata gccaaatttc gccaagtcaa aagaatgatg gttgcagcac
      781 ttgaaattag tctctaacag agtcagattt tcttgacaga taggacaggc aaaggcagtc
      841 gcagaagcaa aacgctgaag tttgggcttg agatttgtat tcatagttta agtgtatcaa
      901 aagaggcaaa tgaaagcaac tttaggaata agtagatggg agattcagta gaaataaaac
      961 taattctcca atttatagaa tgaaattgct tttatatcta aattgctata taataatgat
     1021 aaggaggaaa taagtatgtt aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct
     1081 tcattatttt tgggtggtgt cgcatttggt acccttggtt tgaaaatctt agcaagtaag
     1141 gaagctaaaa aaggttattc taaagctttg gctaaggctt acaagttgaa agacgagcta
     1201 gatgcatctg tttctgtcgt gaagcaacat ggagacgatg tcttgcaaga tgccaaatat
     1261 ttgtacgagc aagagaaaaa agaagagcaa ttagatagcc ttataggtga ataatatgtc
     1321 ttttaaagtg ctacatagag gataccaaca tatccgacta tcatcttctt tttcacttac
     1381 cttggatatt caagactatc ttcgttcctt ggcgagagat gaaaagggga ttgagtctat
     1441 ccagttttac atggatcaac agcactttac tctacgcata aaagaaggct tttctgtatt
     1501 agataatgca gaagcctttt taaaaagaat tgataaaggg aaagtttctg agttgatgac
     1561 tcttcccatt cgtagagaag agagtgctta ttctattgtt tcaggtgcag cggttaagcg
     1621 tgtacttttt cgtagttttg tgccgtatcc tattcgctat atatggactt gttatcaggc
     1681 tttgggttat attagagaag cctatcaaac actagcgcgt aaggaactaa cgatggaagt
     1741 cttggactgt tcggctattt tattgtcttt gtttatgaac caatccaaga cagctagcaa
     1801 tatcatgttt atgcttgatt tggggaatca tttagatcag tggtccttga aaaaaactgc
     1861 aacagattta gaacagagtc ttcttgcaaa agagagcgat gtattcctag tacagggcga
     1921 tacggttgtt agtatcaaga gttccgatgt tcaaatagga gatgtcttga tcttatctca
     1981 aggaaatgaa attctgtttg atggacaagt agtttcaggt ttaggtatgg tcaacgaaag
     2041 ttccttgaca ggagagagtt ttccagttga aaaaagagag tctgatttgg tttgtgcaaa
     2101 tacagtatta gaaactggag agttacgcat tcgtgtaaca gataatcaga tgaacagccg
     2161 tattttacag ctgattgagt tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg
     2221 ctatttcatc aagatggcgg ataaagtcgt caaatataat ttcttggggg ctgggctgac
     2281 ttacctattg acaggttctt tttctaaggc tatttctttc ctattggtcg atttctcctg
     2341 cgctttgaaa atctctactc ctgtagctta tttgacagtt atcaaggaag ggttgaaccg
     2401 tgaaatggtg attaaggatg gagatgttct ggagaaatat ctggaagttg atactttctt
     2461 gtttgataag acaggaacaa tcacaactag ttatcctata gttgaaaagg tgttaccttt
     2521 tggagactat agtgaggaag atattctcag aatcagtgcc tgtcttgagg aacacattta
     2581 tcatcctatt gctaatgcca tcgtcaagca agctgagata gagggaattg aacatgagga
     2641 aatgcatggg aaactccaat atatcgcaag caaggggatc aaatctcata tagatggcca
     2701 accagttctt attgggaatt atgtcttgat gcaggatgag cagattcata tcagttcaga
     2761 acaaaatgct ttaattgaag agtacaagag tcactacaat ctcttattct tggcttatca
     2821 aaatgaattg attggaatgt tctgcattca tactcctttg agaaaagaag caaaaacagc
     2881 cttggataaa cttaaggcac aggggaaaaa attgattctg gcaacaggag acaccttgat
     2941 taggacagag gaattagtca aagatttgcc ctttgatcag gtctatacag acttgaaacc
     3001 tgatgggaaa tttgagttag tagagaaact gcagaaagca ggtcacacta ttttgatggt
     3061 tggagatggc ttgaatgact cagcggcttt aactctatca gatatcggtg tggtgatgaa
     3121 tgagagtgca gatatttcta agcagatgag tgatatctta ttgttagata atcgtttgga
     3181 tttcttccaa gagttggatt cgttatcatc atctttgcaa acactcatca agaaaaatat
     3241 tcaggatacc gttgtcgtaa atagtagttt gattggcttt ggcttattta attggttcag
     3301 tccttcaaat ctctctatct tacataatct aacaaccttg cgcattgtcc tgcgtagcct
     3361 gtctattaaa aatagataga tgagagttat taacagcaaa aaggagttac ctttctcgag
     3421 gttaactcct ttgtttatag atagatgttg aatagtttag taagtcaata caaagtattt
     3481 tttcttccca cgacggataa cagtcagttc attttctaac ttatcagcgt cactcaagac
     3541 atagtcaagg tcttggatgc ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc
     3601 acgggcttgg cgttttgagt taactatacc agatgagacg agcagttcca cgatattgtt
     3661 gttttcgtct gcctgtactt ggtagtttgg cacaccacga agtccttgtt tgagctcttt
     3721 gacagaaagg tttttgatgt ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt
     3781 gtaggcttct tctccgtgaa caagtgtaac aacttcacga gccaagactt tttgagccaa
     3841 gcgttcgtgt ggcgctgctt caaattgttt acgaatatct tcaatctcat caagtgacaa
     3901 gaaagtaaag attttcaaga agcgaacagt gtcagcgtcc atcacgttca tccagaattg
     3961 gtacatttcg tatggagaag tcttttcggg attaagccag acggcatttc cttctgattt
     4021 accaaatttc ttaccagttg catctgtgat tagtggaaca gtgataacgt gaccagtctt
     4081 gtccgcctta cgacgaagca attcggtacc agctgtcata tttccccact ggtcagaacc
     4141 accgatttga agagtgacat tatggtcttg gttaaggacg aagaagtcgt acccttgcat
     4201 gatttggtaa gcgaactcag tgtaagaaat tcctgtttcg atccgttttt taacagattc
     4261 cttactcatc atgtagttga ccgtgaagta ttttccaata tcacggagga agtcaatgaa
     4321 gctgatgctg ccaaaccagt cgtagttgtt gaccatgaca gccttgtttt cgccattttc
     4381 aaagtcaaga aaacgagaaa gttgtccttg gatagacttg acccagccat ctactgtgtc
     4441 ttttgtttgg agactacgtt cagcatcttt gaaggacgga tctccgatga gacctgtagc
     4501 accgccaacg agcgcataag gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat
     4561 tgcgacaagg tggcctaggt gaaggctgtc agcagttgga tcgtagccag tataataaga
     4621 aacttgacct tcttctaggg ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa
     4681 accacgatct tttagctcat caaaaatgtg catgtgtctt ttctcctttt taaaattatt
     4741 gtttctacct attgtatcac aaacttgggc aatagcctag cagaataggg aagaaagtgg
     4801 ctattttatt gaaaatttcc cttttgtggt ataatagata gagtgaggaa atccatgcaa
     4861 aatcaattaa atgaattaaa acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat
     4921 aaaaaatcag ctagacctgg caagaaaggt tcaagtacca aaaaatctaa aacattagat
     4981 aagtcagcca ttttcccagc tattttactg agtataaaag ccttatttaa cttactcttt
     5041 gtactcggtt ttctaggagg aatgttggga gctgggattg ctttgggata cggagtggcc
     5101 ttatttgaca aggttcgggt gcctcagaca gaagaattgg tgaatcaggt caaggacatc
     5161 tcttctattt cagagattac ctattcggac gggacggtga ttgcttccat agagagtgat
     5221 ttgttgcgca cttctatctc atctgagcaa atttcggaaa atctgaagaa ggctatcatt
     5281 gcgacagaag atgaacactt taaagaacat aagggtgtag tacccaaggc ggtgattcgt
     5341 gcgaccttgg ggaaatttgt aggtttgggt tcctctagtg ggggttcaac cttgacccag
     5401 caactaatta aacagcaggt ggttggggat gcgccgacct tggctcgtaa ggcggcagag
     5461 attgtggatg ctcttgcctt ggaacgcgcc atgaataaag atgagatttt aacgacctat
     5521 ctcaatgtgg ctccctttgg ccgaaataat aagggacaga atattgcagg ggctcggcaa
     5581 gcagctgagg gaattttcgg tgtagatgcc agtcagttga ctgttcctca agcagcattt
     5641 ttagcaggac ttccacagag tcccattact tactctcctt atgaaaatac tggggagttg
     5701 aagagtgatg aagacctaga aattggctta agacgggcta aggcagttct ttacagtatg
     5761 tatcgtacag gtgcattaag caaagacgag tattctcagt acaaggatta tgaccttaaa
     5821 caggactttt taccatcggg cacggttaca ggaatttcac gagactattt atactttaca
     5881 actttggcag aagctcaaga acgtatgtat gactatctag ctcagagaga caatgtctcc
     5941 gctaaggagt tgaaaaatga ggcaactcag aagttttatc gagatttggc agccaaggaa
     6001 attgaaaatg gtggttataa gattactact accatagatc agaaaattca ttctgccatg
     6061 caaagtgcgg ttgctgatta tggctatctt ttagacgatg gaacaggtcg tgtagaagta
     6121 gggaatgtct tgatggacaa ccaaacaggt gctattctag gctttgtagg tggtcgtaat
     6181 tatcaagaaa atcaaaataa tcatgccttt gataccaaac gttcgccagc ttctactacc
     6241 aagcccttgc tggcctacgg tattgctatt gaccagggct tgatgggaag tgaaacgatt
     6301 ctatctaact atccaacaaa ctttgctaat ggcaatccga ttatgtatgc taatagcaag
     6361 ggaacaggaa tgatgacctt gggagaagct ctgaactatt catggaatat ccctgcttac
     6421 tggacctatc gtatgctccg tgaaaagggt gttgatgtca agggttatat ggaaaagatg
     6481 ggttacgaga ttcctgagta cggtattgag agcttgccaa tgggtggtgg tattgaagtc
     6541 acagttgccc agcataccaa tggctatcag accttagcta ataatggagt ttatcatcag
     6601 aagcatgtga tttcaaagat tgaagcagca gatggtagag tggtgtatga gtatcaggat
     6661 aaaccggttc aagtctattc aaaagctact gcgacgatta tgcagggatt gctacgagaa
     6721 gttctatcct ctcgtgtgac aacaaccttc aagtctaacc tgacttcttt aaatcctact
     6781 ctggctaatg cagattggat tgggaagact ggtacaacca accaagacga aaatatgtgg
     6841 ctcatgcttt cgacacctag attaacccta ggtggctgga ttgggcatga tgataatcat
     6901 tcattgtcac gtagagcagg ttattctaat aactctaatt acatggctca tctagtaaat
     6961 gcgattcagc aagcttcccc aagcatttgg gggaacgagc gctttgcttt agatcctagt
     7021 gtagtgaaat cggaagtctt gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa
     7081 ggaaaagaag tagaggtcac aggttcgact gttaccagct attgggctaa taagtcagga
     7141 gcgccagcga caagttatcg ctttgctatt ggtggaagtg atgcggatta tcagaatgct
     7201 tggtctagta ttgtggggag tctaccaact ccatccagct ccagcagttc aagtagtagt
     7261 tctagcgata gcagtaactc aagtactaca cgaccttctt caagggcgag acgataattc
     7321 tctaaatgaa gtggccaatc aatggattgc cacttttttc ctttcgtgtt acaataaggg
     7381 tatgaatcag tatcagaaaa agattgttaa cggaaaaatt tattcgctcc tatccggctt
     7441 aatatgggga atctgtggaa ttttaggaga gtacttcttt actcattatc aggtgtcttc
     7501 gggctggatt acctctatgc gtttgacact ggcagggagt cttgtactca tttggtctgc
     7561 aatacaatta aaatcgcaag tgctagatat ttggcgagac aagaaaaatt acctgccctt
     7621 tttagcctat gctattttgg ggattttttc agttcagtat tttttctatc tctgtgtaga
     7681 atactcaaat gctacgacag caactatttt acagtttatt agccctgtct ttatcctctt
     7741 ttataatcgc ttggtttatc aaaaacgagc gtcaaaaagc gctgttttct atgttttggt
     7801 tgccatgctg ggtgtttgct tgatggcgac aaagggagat ctctctcagt tatccatgac
     7861 gccgctagct cttataacag gtttgctgag tgccatgggt gttatgttta atgttatctt
     7921 gccccaacct tttgctaagc gttatggttt tgttcctacg gttgggtggg ggatgatttt
     7981 ggcaggtttg tttagcaatg tcctctcgcc ggtttatcag ctttccttta ctcttgatat
     8041 ttggagtatc ttgatttgcc tcattatcgc tttctttgga acggcttttg cttttttcat
     8101 ttccatgaag gctgtgtcct tggtttctcc tttggtggtt gccgttatca gtgccagtga
     8161 acctctctct tctgctctct tgagtgtttt gttcttagga ttagtagtgg attggtccct
     8221 ccttctagct atagccttga ttattttacc catgatattt ttgtctatag aagaagcgaa
     8281 agaaagtaga taaaaagtct tttcttaatt ctaaaagtgt gctatactag aatagtcaat
     8341 aaaacacggg gagatagttg tgaagagtgt ttttaggttg tatcggtagg ggcttgcttt
     8401 taccgacagc acgttttatc tcacatccct aaaaaatcat acctaaaaac agacaaaaag
     8461 gtttcaaatt tgaggccttt tttggtagaa taggtatcat tataacgaac caggaggcac
     8521 ctatgactgc tacaaaaatg aacgctcaag aaattatcca atttatcgcc aatgctgaaa
     8581 agaaaaccag tgtcaaagta acctttgagg ggcaactcgc aactgctgtg cctagctctg
     8641 ttgtcaaact aggaaatgtc ctattcggag actggaagga cgtggctccg cttcttgaag
     8701 gtttggtaga aaatcaagat tatgttgtcg agcaagatgc tcgtaattct gcagttcctt
     8761 tgctagataa gcgtgctatc aacgctcgta tcgagccagg tgctattatc cgtgaccagg
     8821 tggaaattgg tgacaatgct gttatcatga tgggagctgt tatcaatatc ggtgctgaaa
     8881 tcggtgctgg aaccatgatt gacatgggtg ccatccttgg tggccgtgct atcgttggaa
     8941 aaaatagcca cgttggtgca ggtgcagttt tggcaggtgt gattgagcca gctagtgctg
     9001 aaccagtccg tgtcggagac aatgttctta tcggtgctaa tgcagtggtt atcgaaggag
     9061 tccaaatcgg tagtggttca gttgtcgctg caggagctat cgttacccaa gatgtcccag
     9121 aaaacgtggt agtagcaggt gttccagctc gtatcatcaa agaaattgat gcccaaaccc
     9181 aacaaaaaac agcgctagag gatgcgcttc gtaccttgta attgtaaaag taaaaaagag
     9241 gcggaaccct ttttccagcc tctttctgct atatcggagg acagatagat gttagatttg
     9301 attcagacta gacgagcttt acaccagatt ccagagattg gcttggagga gttcaagact
     9361 caggcttatt tgctggatgt gattgagaaa ttgactacgg gcaaggattt tgttcaaatt
     9421 cgtacttggc ggacagggat tttggtctac ctgcagggaa gtcagccgga gcgaaccatt
     9481 ggttggcgga cagatattga tggcctgcct atcgtcgaac aaacaggtct accttttgct
     9541 tctcaacacc aaggtcgcat gcatgcctgt ggccatgatt ttcatatgac cattgcctta
     9601 ggctgtcttg agcgcgccct tgaggagcaa cccaagaata atctgctctt tctatttcag
     9661 cctgctgaag aaaatgaagc tggtggtatg ctcatgtatg aggatggtgc ttttggagat
     9721 tggttgccaa accaattcta tggtctccat gttcgtccag atttgaaagt cggccagatt
     9781 gcgactaata ctcatacact ctttgcagga acttgcgagg tgaagatccg tttcaaaggc
     9841 aaaggtggcc acgcagcttt tcctcatgaa gccaatgacg ccttggtggc ggctagttac
     9901 tttgtgaccc aagtgcagtc agttgttagc cgcaatgtca acccaatcga gggagcagtg
     9961 gtgaccttcg gcgtttttca agctggaacc accaacaatg tcatcacaga cacagctttt
    10021 ttacatggaa ctattcgtgc cttgacacag gacatgagtc tcttggtgca aaagagggta
    10081 aaaacagttg cagaaggggt tgcagctgcc tttgatatgg aagtcgaagt ggaactcaaa
    10141 caaggtggat acctacctgt tgagaacaat ccagccttgg cgcgtgaact gatggacttc
    10201 tttgacgaaa aagacggaat cgagttgatt gatatcgaac ctgctatgac aggcgaggac
    10261 tttggttatc tcctttcaaa ggttgatggc gtgatgtttt ggctaggtat cgatagtccc
    10321 tacgctcttc atcaccctca aatgagtcct aaggaagaag tcttagctat tggggtggct
    10381 gcggtgtcta gtttcctgaa aaagaaggca gcagaataga gggcttgtct atgaaatcgg
    10441 aattacgcaa gcaagtcttg caaggaatga aggctatatc tcaagaacaa aaacagttta
    10501 tagatcaaac tttaaccgag cggcttttac accatccctt ctatcaagaa gccaaggtca
    10561 tcgcaaccta cctctctttt tctcatgagt ttcaaacgcg ggaactgatt gagcaggcgc
    10621 tgaaggacgg caagaaggtt ttaataccca aaacttatcc caaggggcgc atggactttg
    10681 tagtctatga tctgcagcag ttggtaaaaa ctgcctttgc cttactggag ccacagggag
    10741 atttggaagt ggtggatgta tctcagattg atttgattca tgttcctggc ctggctttta
    10801 cgacggatgg atatcggatt ggatatggtg gaggttatta tgaccgctat ctggaacatt
    10861 tttctggtca tactttgagt acggttcatc cttgtcaaat tcaggacttt atacctgaaa
    10921 accatgatat tcctgttcag gaggtattaa ttgatgaagg aaatctttga tagacgttac
    10981 cctgtgacga gtttcttcct cttagtgacg gccttggtat ttttactaat gttggtcact
    11041 gcaggcggga actttgacag ggcagataca ttatttcgat ttggagccat gtatgggcca
    11101 gctattcgcc tctttcccga gcaggtttgg cgtctcttgt ctgccatttt tgttcatatt
    11161 gggtgggaac atttcattgt taatatgctt tcactttatt atcttggaag gcaggtagag
    11221 gagattttcg gttctaagca gtttttcttt ctctatcttt tatcaggaat gatgggcaat
    11281 ctctttgttt ttgtatttag tcctaaatcc ttagcagcag gcgcctctac ctctctttat
    11341 gggctatttg ccgcgattat tgttcttcgc tatgcaactc gcaatcctta tattcaacag
    11401 ctagggcaat cctatctgac actttttgtg gttaacatta ttggaagtgt tctgattcca
    11461 ggaatcagcc tagcaggcca tatcggtggt gcagttggtg gcgcatttct agcagttatc
    11521 tttccagtta gaggagaaaa acggatgtat aataccagcc agagattagg agcggtagtc
    11581 ttgttcgtag gactcgccat tttgcttttc tacaagggaa tgggaatgtg acgaagttga
    11641 aagaaaattt gtgtaatgaa aaaagataag gcattttttg aaccttatct ttttatttta
    11701 ttccttctca gtcaattctt ttccaagttg gatgaggtaa ttcttcaaat catctttgac
    11761 ttgtggatgt ttgagggcgt agtcaataga tgttttcata aagccaaact tatccccaac
    11821 gtcgtaacga gctcctgtaa attcacgggc aaaaacacgc tgtgttttat taagagtatc
    11881 gattgcatca gtaagttgga tttcatttcc agcaccagga gcttgctttt cgagaatctc
    11941 aaaaatttca ggcgtgagga ggtagcgtcc gataatagca aggtcgctag gagcgtcctc
    12001 tggagctggt ttttcaacaa aggtttcaac actgtaaaga ccatcttttc cttcgccttg
    12061 cggagcaata accccgtaag cagatacttc gtcatgaggg actggcatga cagcgatagt
    12121 agacgcgtgg gtacgctcgt agtcatccat gagttgtttg gtaagtggaa cagtcttttc
    12181 gtctgtgata tccatcaagt catcacccag cataacaaca aaaggttcat ttccaacgaa
    12241 agccttggct tgcaaaacag catcgccgag accacgtgga tgcgtttggc ggataaaatg
    12301 caggcgcatg ccagttgttt catcaactag cttcagaaga tctgttttcc ctttttcttt
    12361 gagattatat tccaattcaa agtttgaatc aaagtggtcc tcaatagaac gttttgattt
    12421 accagtgaca actagaatat cttcaatacc tgatttgaga gcttcttcca cgataaactg
    12481 gatagttggt ttgtctacga ttggcaacat ttctttggca agggccttgg ttgctggtaa
    12541 aaatcgagtt cctagtccag cagcagggat gactgccttt ctaacttttg atgtcataaa
    12601 aatcctttct atagagggtt aagaccactc attttctgct ttaaattcat tgttcatgat
    12661 gtcataaatg gcatctttga tattggttcc gtgataaata acttggtaaa tagcctgtgt
    12721 aatgggcata tagactccaa gttcttgggc tagttcatag gctgctcgag tcgttgaaat
    12781 tccttcgatt accatgccca tattagcttc tatatcagct agggattctc ctcgtccgag
    12841 agcatctcca gctctccagt tacgagagtg gatggaagtt cccgttacga tcaaatctcc
    12901 cacaccagat aagccgctat aggtcaatgg actggccccg agtgctaccc ctaggcgggt
    12961 gatttctgct aaacctcgag cgatgatggc tgccttagca ttatcaccaa atccaagacc
    13021 atgtaaagct ccagcaccga cagcaataat atttttaaga gcaccagcag tttcaacccc
    13081 gataacatcc gtattggtat aaagtcggaa gtagtgatta ctaaatagct cctgaacgta
    13141 ttgagctgtt tgtaaatctt tagaagcagc agttattaaa gttaggtcac gcacaatggt
    13201 ctcttctgca tgactaggcc ctgaaacaac gacgatatca ctacggagat gttcaggaat
    13261 ttcttcttca agaatggttg ataatcgttt atggctatca ggttctaatc cctttgatgc
    13321 gtgcatgatg ataaccttat ggtccaaggt ttgtgcaact tgctgggcaa caagtcgtgt
    13381 cacttttgtt gggacaacaa acaaaatcgc atccacattt ttcaatgttt ctgctaagtc
    13441 ggtgtaggca atgatatttt cgtctagaac gacatcttta aagtagtgct tattagtatg
    13501 gtgtgtatta atttcattga tttgctcggg aagatttccc caaatacgta cctcgtgtcc
    13561 attgtcattt aagacttgtg aaagggcggt tccccaagaa ccaggcccca agacggcgac
    13621 ggtttgtttt tccatgattt cctccttgat agatttcttt ctcttattct atcatattct
    13681 aggggatttt gcacttgcat tactggggta tggtggaaaa atacacaaag accgagatga
    13741 agggataaac tcttagtctt tagttaaagt gagaagaaat ctgatagata gtttgattca
    13801 gtatatgctt ataatagagg taaacaactc aggaggttct tgtaggttgc gagagtttgg
    13861 cgaaaaaatt aaaagattac gtttggctaa aaaaatcagt cgttcagaat tttgtggtga
    13921 tgagtctgaa ttaagtatcc gtcaattaat tagaattgaa aatggagaat ccagaccaat
    13981 actaacaaag ttaaaatata ttgctgaacg tttggaggtt gaagattaca agttgatgcc
    14041 aagttatata gagttggata aggaatacct agaattgaag tatttcttga tgaggactcc
    14101 tacatacgaa gatgaaacta tcgcccaaaa gaaagagagt gtttttgcta agatttttga
    14161 agagtattat gataggctac ctgaggaaga aagatttatc atcccaaatt attcatatct
    14221 agcactagcg aactacacag ttcaaaaatt accagaaaag ctagttgaaa tactgtcctt
    14281 ctggtgattt tgcttaattt ctgatgttag agacataatt gaggagattt gtcttgattt
    14341 tttcctaaaa aagggcagac tcctcccttg gtttgatgct cgatttttaa aataaggtga
    14401 cttattctgt taggcatgtt ttcccctgcc ctctagctct atatggaaca gggagtatca
    14461 gatttatctg gcagattgta tcaaataagg cttgaaactg ttttgaatag gcgtatagac
    14521 ttgagaattt gagaatatgt cgtctagcag tagagacata ttttccggca atatgaagga
    14581 agagacgtcg aaaacgcttg atagtcaagg cctttacttc atcaccagct agctgcttta
    14641 aaaagaggta gagattataa gccagacagc ccatcatcat acgtacttca ttcttaatca
    14701 tggtcgaact atctgtctta tccccaaaga atcctgcttt cctttctttg ataaagtttt
    14761 cagcattccc tcgttcacga tagaattgaa acagctcctc actatctaca ctgcttaaat
    14821 tggtcaaatg aactttttta caaccataaa aaagagcact taatcgtact cttctctttt
    14881 aaggattagt tgaattaatt caaatccact agttctcctg tttctaggta gactaggcgt
    14941 tcacaaatgt tagcaatgta atcagcgaag cgttccagat gccctatgat ataaaggtat
    15001 tgtgttccat tgggaattga ggtttcttgg tctttcataa gtccaatgat ttcctttgat
    15061 aaggcataat aatattggtc aatctgttca tctttttgag caatactaat agcttttgag
    15121 gcttggtgca aaggaaaggc aaccaataaa tcggatagca tgctgaggga taatttaccc
    15181 atttggtgta actgttcttc gtcaggggct agttgatttt cttttagttg caaaacagct
    15241 ttagcaatgc ctgccatatg gtctcccata cgttcaaggt ctgaacaaga agacatgatg
    15301 ctaatcacaa atcgaaggtc agacacttgt ggctgctgca aggccaacaa acgggcacag
    15361 gtcaattcga tagcgctttg accttggttg atagcatgat ccttattgat aattagctct
    15421 gccatctcct tgtctttgga ggctaaggcc agtaaggttt ttgaagctgt ttcaaggaca
    15481 agttgcccta gtcctaaaaa ggattgttct aattcatgca attctaagtc aaattgattt
    15541 ctcataggtt tttccttcct tatccgaacc gtcctgaaat atagtcttct gtgcgctgat
    15601 cttttggatt ggtaaacacg tcaacggtgt ctccaaattc gcaaatttct cctgttaaga
    15661 aaaaagcagt tttatctgaa atacgtgaag cttgttgcat gttatgggta acaatgataa
    15721 tcgtataatc cttttttagt tgctgaatga ggtcttcaat ttttaaagtg gagatagggt
    15781 ctaaggctga agtcggctca tccattaaca gaacatcagg ttctactgct aaagctcgcg
    15841 caatgcaaag gcgttgctgc tgaccgcctg ataaggacat ggcactcttt ttaagattat
    15901 ctttgacttc gtcccaaatg gctgcccctt ttaaagattt ttccactaag gcatctaatt
    15961 gttttttgtc tcgaatacca tgtgtccttg ggccataagc cacgttatca tagatagaca
    16021 tggcaaaggg attaggctgt tgaaaaacca tccctacacg cttgcgtagc tgattaaggt
    16081 tgaatttgct actataaata tcttgctcat ctaagaggac ttggccttca atatggcaag
    16141 aaggaaccaa atcgttcatc cgattaaggg tttttagaaa agttgattta ccacaaccag
    16201 atgggcctat caaggcagta atctgtcttt ctggtaattg aatcgaaata ttttttaagg
    16261 cttgaaaatc cccgtaaaat aagtctaggt gtctgactga aaatgttccc atactaggaa
    16321 gctcctttca caagttttcg agataataag cttgatagag tatttatcat taaaacagta
    16381 ataatcaaaa tcacaccggt agcataggct tcattgacat gtagcccctc acttgacagc
    16441 atatacatat gcagggctag agaacgacct gaagacatga gactacttgg cgtattggta
    16501 gaggtaccta atgtatacat gagggcagct gtctcaccaa cgatacggcc aatagctagt
    16561 atcactccag ctaaaatacc tggcatggca actggtagaa caattctaaa aacagtccgt
    16621 aacttacctg ccccaagtcc ataacttgct tgacgcatgc tatcactaac agataaaagg
    16681 gcttcttctg ttgagcgaat aatgactggc aacaccatga tgactgaggt taagattcct
    16741 gataacagag agtattgaaa acctaagaag actacaaaga agagcatgcc aaacagacca
    16801 aaaacaatgg aaggaatccc agacaaggta tctgaggcca atcgcataat tttaacacaa
    16861 agggaatctt tttttgtata ttccacaaga taaaaaccag caaaaatccc tatgggcaag
    16921 gctaaaagaa gagcaccaaa aaccagaata acggtggaaa taatcgctgg cataagggaa
    16981 atgttctcag aagtataagt ccaagaaaag agggatagac ttagatgagg taagcctttg
    17041 atgaggataa aaccaatgat taaaaagaga gagccaaagg ttaaagctga aaaacaataa
    17101 acgagaagtt ttagcaggta tttactcata agatgatttt cctttcaagt aggcaaagta
    17161 ggcattaatc aagagaataa ggaaaaagag aactgctgag gttgcaataa gggcttccct
    17221 atgctgacct gatgcgtaag ccatttccag aacaatattg gttgttaagg ttctggttcc
    17281 tgaaaagagt ccacttggaa taatcggctg gttgcctgcc accaaaataa ctgccatggt
    17341 ttcacctact gcgcgaccga ttcctaaaat aactgctgat aaaataccag atctcgcagc
    17401 tggcaagatg acactaaaaa tactccgttc atgactagct cctagagcca agctaccaga
    17461 ataatacgtt ttgggaactg ttcggatagc agattctgac aaactgataa tggttggcaa
    17521 aatcattatt cctaatagta acgaagcggt taggacactc atgccatttc ctaaaaaggt
    17581 tctaatccaa ggcaccaata attgtaggcc gaaaaaacca taaacaatag atggaatggc
    17641 cgccatcaag ttgatagctg attttaagaa gccatagacg ggctttggac aataataaac
    17701 cataaacacc gatgtcaaga tgcctgttgg caccccaatc acaatcgctc ctaaggtaat
    17761 taataaggaa ccaacgatca ttggtaaaat accatagctt gccggaatgt tcgttggcga
    17821 ccaatcactg cctaataaaa aacgggcaaa gccgtagtta gccatgaaag gtaagccatt
    17881 actaaaaata aagaaacaga ttagcaaaat agctacaaca gctactgttg cactcatgaa
    17941 aaaaattgcc ctaaaaactg cttctttgaa ggcttgtttt atcacatctt gtcctttcta
    18001 gtgaagaaag taagggagat acgacacctc cctacttgcc ttctttatct tattgtacga
    18061 tgaaacgttt gcatctcttt agagatttat ggagcaaaca ttttatttaa tcttgtccca
    18121 ggtggttaat ttgccactaa aaacgtctgc aagttcagcc atactgactt ggcttgcctt
    18181 attgtcatta ttgaccacaa cagcaatacc gtctaaagca atagcatcat gggtgagact
    18241 cttaccttct tcaggagtta attccctaga aaccatacca atatcagcgg ttttctcctt
    18301 aacagcggta atacctgctg aagatccatt agaggtaata tcaatcgtaa cttctggatt
    18361 ttctttttta taagcttctg ctaatttttc cattaaagaa gatactgaag tggaacctac
    18421 aacagacaac ttgcctgata agtgttggct tgtatattct gtggtttcgg ttttagcttc
    18481 aataaattta ttatctgtga ccacttgttg accttgtttg gagtggataa agctgataaa
    18541 atcttgacct agcttggaaa gattagaaga ccaaacaatg ttgaagggac gttgaagagg
    18601 gtattcacca tctaaaactg tgtctcgact agccttgaca ccatcaatct ctaaagcctt
    18661 gacagatttc gttaaagatc ccaaggagat gtagccgata gcattagcat tcccttgaac
    18721 tgctgagaga acaccttctg tactattttg aatcacagct gttttggtag tgttgtcaat
    18781 ttttttatca ccgtcttttt tgagaatccc tgtgatttct gtgaaggcac cccgtgttcc
    18841 agagccattt tctcgtgaaa tcacctcaat cgttcctgaa gctgactgtt tggaagcagc
    18901 tgactgattg ccacaggcaa caagcccaaa tcctgataag ccaatggctg caagagtaag
    18961 catttttttg aatttcataa taatcacctt tatctctatg tatttttctt gtgtaggctt
    19021 actacattta tagtctaaca agtctttgta aaggtttatc cctgattcat gtaaagattg
    19081 tgtaaagaat caaaaaaagc cacttttgaa aaatggctgc tcctaaaaat agctttaaaa
    19141 attattagtc ctgtgcgaaa gattggttag gaagaaaaat cgtgaagcaa ctgcctctgc
    19201 caagctgact cgtcaccgtg acttggccac ctaataattg actgagttct ttgacaatgg
    19261 caaggccaag accagtgcca ccagtttgtc tgcttcgacc tttattaact cggtaaaaac
    19321 gttcaaaaat acgatcctgc tctaattgac taataccaat ccctgtatct gatacagaaa
    19381 tcttaatgcc ttcgttcacc ttttgggtct tgacctcaat ttttccccct tgttcagtgt
    19441 aacggatggc attggataaa agattgagta agatttggga aagtaattga ctatctgata
    19501 cgagggtgac atcatctggc acctgcacct ttagctgtaa atccttcttc ttgagctgag
    19561 gttgcaagct ttgagtcaaa tcctgtacaa attctgccaa agaaagggtc gtccattgta
    19621 taggcatttg ttgagcctta gataaggtaa gaagatgctc aacaatatgc tcaagacgca
    19681 aactttcttt gtaaataatg tctagaaagt catccttgag cgcttcttct tcagctgaca
    19741 tccccttaat ggtttcagca aagcccttaa tcgaagtaac tggtgtcctc aattcatggg
    19801 aggcatttga gacaaaggct aaatttaact tttcataagt tctaatcgtt gttaaatcat
    19861 atagcaagac gagcacagct tccacagatt gggtggggct aaaaacggga actgctgtca
    19921 cttctaaaat caagtcaccc tcatgaaacc cacttacttc ttgttttaac cttgtttttt
    19981 gatcaaaggc ttggtgaact aaattccgaa tatccatccg tttgaggtca tcaagtgaac
    20041 ttatgtcgcc gtccacatcg ggaaaataat gaggcagaga gcgactggat aataacatct
    20101 gaccttgagc ggaaactaaa aacgtcccca tggttaggtg cgacagaaga acctccattg
    20161 tttcggctag atccttgtat tgctgatcct gttgggagac tttggttttt aggccagaca
    20221 catactgagc caaagacttt aagtcttctt gccctttttc taaaaagtat tcactactgg
    20281 tcaagagagg ttggtgcaag gtctcaaaag caacttccca tttccaaagg caaaagagcc
    20341 agtagccacc tagtcccaaa gaaagggcta gaagaaagag accgatgcct ttactgatcc
    20401 aagttaatgc catccctgca atcagaatga ggctaacact tagattgact agccaaaatt
    20461 gaaggtagcg tttcatctat aactccttga acttataacc atacccccga atggttcgaa
    20521 taaattgagg ggctttagga ttgtcttcaa ttttttccct taacttacca atatgaacgt
    20581 ccaccaaacg tgtttcctgc ccaaagtcat acccccagat acgttccaaa agacgctctc
    20641 tagtcagtgt catgttggga tgtttcataa gatagagcaa gagttcaaat tcttttgggg
    20701 tcaaactcag taacttattc gccttgtaga cttcatgacg ctcagggtat actttcaagg
    20761 tcccaaatag ccaagaatcg tcagcgatat tatctgaatc atctccttct tgttctcctt
    20821 tagttcgcct gaggacagcc ttgacacgcg ccagcaattc tctagggcta aaaggcttgg
    20881 tcaggtagtc atcagcccct aattccaagg ccaaaacctt atcaaattca tcacttttcg
    20941 cagaaaccat cataattgga gttttgacgc ctttggctct cagccgctta caaacttcca
    21001 tgccatctaa ttgtggtaac atgatatcaa gcaagataaa atcaaagggt tctgtttctg
    21061 ccaaagctaa ggccttccgt ccatttgtta ccaattgagt agaaaagcct tccttactta
    21121 aatggtagtc aagcaatttc agaatgtgtt cttcatcatc cactaataag acttgttttg
    21181 tcatctatta tctcctattg gtaacattat accacaatta tcagaaatcc taacattgct
    21241 aaatcagatt aaatttgctt atcaagacta gtatctggtc aaacgctcaa tcatctcctt
    21301 gtgctctgga taggtcgcca gtagatctac cctttcaaat aattcaaaat cctcaaattc
    21361 aaaaccagga gcaacaagac aagaaaccag agcatcatcc ttatcaactg ttgatcccca
    21421 aatagtgccc ttaggaacac agtagtgaag ttgttgccct ttggatatgt ccaggcctaa
    21481 agtgactgct tcgtagtgac catctgctgt aatcatgtga acagtaagtg gggattctgc
    21541 atgaaaatac cagatttcat ctgctgtcaa tcggtgaaaa tgtgaaggat tcgtttcttc
    21601 ttaataagaa ataaatactg gtataaagcg cccttccctt accagcaagg tttatagtgt
    21661 ctgaagcttt ttttgtttgt ctaaaatagc caccttcaac atggggagct aactctagag
    21721 ttcttatcaa gtcttctt
//
LOCUS       DBEROT010000036        20979 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.36, whole genome shotgun sequence.
ACCESSION   DBEROT010000036 DBEROT010000000
VERSION     DBEROT010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20979
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.36"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..1152
                     /locus_tag="ACL8CG_001616"
                     /pseudo
     CDS             1..1152
                     /locus_tag="ACL8CG_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
     gene            1226..1399
                     /locus_tag="ACL8CG_001617"
     CDS             1226..1399
                     /locus_tag="ACL8CG_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344176.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            1585..2112
                     /locus_tag="ACL8CG_001618"
     CDS             1585..2112
                     /locus_tag="ACL8CG_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGS1344177.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            2239..2967
                     /locus_tag="ACL8CG_001619"
     CDS             2239..2967
                     /locus_tag="ACL8CG_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGS1344178.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            3651..3812
                     /locus_tag="ACL8CG_001620"
     CDS             3651..3812
                     /locus_tag="ACL8CG_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344179.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            3904..5583
                     /locus_tag="ACL8CG_001621"
     CDS             3904..5583
                     /locus_tag="ACL8CG_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGS1344180.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            5851..6417
                     /locus_tag="ACL8CG_001622"
     CDS             5851..6417
                     /locus_tag="ACL8CG_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344181.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            6738..6926
                     /locus_tag="ACL8CG_001623"
     CDS             6738..6926
                     /locus_tag="ACL8CG_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGS1344182.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            6988..7746
                     /locus_tag="ACL8CG_001624"
     CDS             6988..7746
                     /locus_tag="ACL8CG_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS1344183.1"
                     /translation="MVVYIRQSNLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            7804..8658
                     /locus_tag="ACL8CG_001625"
     CDS             7804..8658
                     /locus_tag="ACL8CG_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGS1344184.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            8770..9654
                     /locus_tag="ACL8CG_001626"
     CDS             8770..9654
                     /locus_tag="ACL8CG_001626"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS1344185.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            9817..11435
                     /locus_tag="ACL8CG_001627"
                     /pseudo
     CDS             9817..11435
                     /locus_tag="ACL8CG_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            11710..12165
                     /locus_tag="ACL8CG_001628"
     CDS             11710..12165
                     /locus_tag="ACL8CG_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344186.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNIIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            12610..13086
                     /gene="pezA"
                     /locus_tag="ACL8CG_001629"
     CDS             12610..13086
                     /gene="pezA"
                     /locus_tag="ACL8CG_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGS1344187.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            13086..13847
                     /gene="pezT"
                     /locus_tag="ACL8CG_001630"
     CDS             13086..13847
                     /gene="pezT"
                     /locus_tag="ACL8CG_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGS1344188.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            13875..14165
                     /locus_tag="ACL8CG_001631"
     CDS             13875..14165
                     /locus_tag="ACL8CG_001631"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344189.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFLVILIRLFFLVQKNILVFLC"
     gene            14159..15031
                     /locus_tag="ACL8CG_001632"
     CDS             14159..15031
                     /locus_tag="ACL8CG_001632"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344190.1"
                     /translation="MLAEAIIKNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDI
                     HPHILHGVEISAADKLHIVCIYDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNN
                     QKIVNYIAHFNSYDILKKGSHLSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKE
                     VGVLSLGQKVVAMLDFLLAYSDYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQ
                     RQIILATHNATIVTNSMTDQVVIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDS
                     FKHKMSIYETALSE"
     gene            15850..16209
                     /locus_tag="ACL8CG_001633"
     CDS             15850..16209
                     /locus_tag="ACL8CG_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGS1344191.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSSFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            16219..16584
                     /gene="mobC"
                     /locus_tag="ACL8CG_001634"
     CDS             16219..16584
                     /gene="mobC"
                     /locus_tag="ACL8CG_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGS1344192.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIDKSHCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            16571..18421
                     /locus_tag="ACL8CG_001635"
     CDS             16571..18421
                     /locus_tag="ACL8CG_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="HGS1344193.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSYEEMVEMYNVNFTNNDKLYEYRNDRQEKHQQNIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQKYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFAKQEIASRLEFLLNC
                     VNSLEALLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEENQKKYKVYIRETTSYFVYNK
                     EHLDKNQYIKGRTLIRQLTNDSRVIPYRRPTVERLQEKISEISLLIELTETDKKYQDI
                     KDNLVSEIAELDIKLTQTNEKIATLNKMAEVLIDSKSEGSGSQKLARHEFSKLNMTES
                     TTLEQVNEELLKLQQEFGNVLDEYEKTIRKLGQLFKVFDECINKEIMNEI"
     gene            18677..20109
                     /locus_tag="ACL8CG_001636"
                     /pseudo
     CDS             18677..20109
                     /locus_tag="ACL8CG_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         7879 a         2979 c         4121 g         6000 t
ORIGIN      
        1 gatgaaaaag gagaaaaagt attaaacaaa aatggaaaac caaagacaag aaaagtagaa
       61 ctaacaacct ggaacgatac aggcaatgta gaacaatgga gagaaaattt ttcagatctt
      121 tgtaacaaat atttagaaag agcaggagca gaaaaaagag tagaccatag gagttttaaa
      181 agacaaaatt cagattatct accgacaatc catttaggat cagcagcaag tgcaatggaa
      241 agaaagggaa tagaaactga caagggaaac tataatagag aaataagaaa atataatcaa
      301 cttgtaaaaa caataaaaga agagataaaa acattaaagg gttggatagg aaatttatta
      361 gataacttat ctactgctta tgaaaaattt aaggatatcg aaagagataa ggtaatagac
      421 aaccctaaac tttttaatct aacaaattat ctattaactt attcagaaat tcaaaaagaa
      481 aaaagtaaat atctaaaagg atatgcaaaa actaataaag aaaaatatga cttcaaaaag
      541 ctaacaagtg catatagtta tttaagaaaa aacaacatag aaaccatagg tcagttacaa
      601 acaaaaatag aaactttaaa gtctaatagt tataggctaa ataaaaaagc aaagacaatc
      661 cataaagaaa tggaagatgt agaaaagaaa attctatact atgaaatcta caaagccaaa
      721 aaagaagttt atgaagaata tcaaaagaaa aatatattca caaaagaagc attttataac
      781 aaacataaga aagatataga ccaatataaa gtagtaagtg ggaaattaaa aaaactccta
      841 tcagataagg aaaaactaag tcctaaaaag tggaatgaag aaaaaattct tttaatgtaa
      901 aatcttgaag aaataaataa agaaaaagac aagataaaag atgaatacca ggaaattaat
      961 catataaaat attcagtaga ttttgtaaac aaagaacttg gtatagattt atccatagaa
     1021 atagataagc taataaaaca gggagaaaaa ccaagtgtaa tagcacagat taaaaagttc
     1081 caagaccaag tcaataaaga taatgaatac agagaaatga tgaaaaacaa gaaaatggat
     1141 caagaaagat aagacctggt aaaaatatct tatccaagct ataatatgac caaacaacta
     1201 aagtcagatc taggaggtaa tagagatgaa taaaaggcaa gagctaatag atgaactcat
     1261 aaaagcaaat gaagatggaa catacaaaac ctataaaagc acagaagaaa taaaagcaat
     1321 gaacaatgaa gaaatacaga ttatatattc caacatgaaa aactatctat cagacaaaag
     1381 aacacacata aactattaaa ggtggaaagg tagtgtaagc tatttttaaa agtataaaag
     1441 gtacaaagac ctaagaaata tataaaaaca tcaaaataaa gtattccacc accaagaaca
     1501 ataaaataaa aacaagcaaa gggaagtata gaaaaattaa aacctatact tccctttttt
     1561 aattcaaaca aaggagagaa aagcatgata aacgaagaaa taagcaagga agcaggtcaa
     1621 gcagcacaaa ccataatatc atacacaata aaggcaacaa aagaatcaat caatttagaa
     1681 aaagaaataa gaaaaaagat gaatgaaact ttagaaaaag caaatggaaa cttaaaaagt
     1741 cttatgggcg atgaaatgaa aataaaagat ctctacaaga aaggacaact agaaaatata
     1801 agcatagatc aaatcgacct caaagactta aaaaaagaac taaacaaact tggagtaagt
     1861 ttctcagtaa tgaaaaacaa agaaagcaaa aactatgaaa tattcttcca agccaaagac
     1921 ataaaagtaa tggaatatgc ctttaagcaa gtcatagcca aggaaaataa aaaagaaaaa
     1981 gaaagtatcc taaaacaaat aaagaaatac aaagacctat ccaaaaacaa agataagaca
     2041 aaagaaaaag gaaaaaggaa agtaaaagaa aaagtaaaac caaacaaaaa agatatgacc
     2101 agagaaatct aaagggagta acgaaaagtt acacccttaa ataaccataa taacaagact
     2161 tccgaaaaac agaagtccag aattccgaaa atcggaaatc aagaatttcg attatcgaaa
     2221 atcaagaaag gagcagatat ggcaacaaac aaaagatact attggataaa attaaaagaa
     2281 gaatttttca cagacaaaag gataaaaagg ttaaggagaa tatctggagg agatacctat
     2341 acgataatct acctaaaact tctactacta agcctaaaag atgagggcaa actctattat
     2401 gacggagtag aaagtgattt tataaaagag ttagcactaa ccatagatga aacagacgat
     2461 gatgtaatgg taacagtaaa ttatttaatc aatcaaggct tattagaagt tgtaacagaa
     2521 aatgatgaat actacctaac tgaaatacca aacttaatcg gatcagaaac agcctgggca
     2581 gagaaaaaaa gaagatacag acaaaataaa cagaggacat tgtccttaat gagtccaacc
     2641 catgtccgac aagagataga gatagagaaa gatatagaga tagataaaga gagagaggga
     2701 gagatagata aaaagtccac ccccattttt tatggagaat tcaaaaatgt aaggttaagc
     2761 aaagaagaat ataaaaatct aaaagaaaaa ttaaactcac acacagatat aatgataaat
     2821 aaactatcca gatacatgga aagcagtggt aagacctatc aaaaccacta tgtgacaatc
     2881 ttaaaatggt atgaagaaga taaagacaaa ctaagacaga aaggtttaaa taaaaaaatg
     2941 aattatgatg taggagaatc tttatagata aaaagaggtg gaaaggcact attaaagact
     3001 ttaagtttaa aaaggtatca aagtatgcca gagataaaaa aatataaata tgacacttta
     3061 aaggcgatta gaaaattaaa gaaatgctag aagactttta gatgacagtt accaagaggg
     3121 tctaattttc actgctactt atgcagtagg aattggacct ttttatataa gcaaattcta
     3181 tttcaaaatt ggttaccaag aaagacttct tttcactgtt aagtataaga gggtaattta
     3241 tagaattttg ttacatcaag ataaatattt tctgatggtc aaattttaaa aagattaata
     3301 actctcgata aattttgaac cttaacaatt gaatagacca agacaagacg ttaattattt
     3361 ttggagcgta ataacctatc cgtcaagatc tttcggctga ataattcggc aaaaaaagtt
     3421 ctgctaagca aaaagaaagt gagcgataag taagagtttg aatataggga gggataccct
     3481 atccgctatg aagaaaatga ggataatgat acttctaagg ttgaagccgg ctcatccgga
     3541 atagaggcgg aggtgagatt cctatgttgc taatccaaag cacttgtcaa tgtcaaaaaa
     3601 cttaattaaa caaataatta ttagatataa aactttagag gaggtatata ttggacaatg
     3661 actggaatgg attggctgat ttaatagcaa atctgattgc aaaatatgct ggtgctttag
     3721 atttagataa tctacccgat ccaacgccag caaaaaatca agagatgaaa aatagttttg
     3781 acatggcaaa aacacaaatt gagacggact aataaaagtg ttataatata cttgaaatga
     3841 tagtccaaac ttaaattaaa aaaattatat atgatataga aaaattatat tgaggttaat
     3901 actatgtcaa aagaaaaaat aaaagtatac ctctatacac gagtatctac gtcaatacag
     3961 atagaggggt attcgttaga ggcacaaaaa tcacgaatga aagcttttgc tatttacaac
     4021 gattatgaaa ttgttggaga gtatgaagat gccgggaagt ctggcaagtc tattgaaggt
     4081 agaatacagt tcaatcgaat gatggaagat ataaaatctg gaaaagatgg agtatctttt
     4141 gttcttgtgt ttaagttatc aagatttgca agaaatgccg ctgatgttct ttctacactt
     4201 cagataatgc aggattatgg agttaatctt atctgcgttg aagatggcat tgattcatct
     4261 aaagatgctg ggaaactaat gatttctgtt ttatcagctg tggctgaaat agaaagagaa
     4321 aacatccgta ttcaaacaat ggaaggttgc attcaaaaag caagggaagg aaaatggaat
     4381 ggtggctttg ctccgtatgg atataaactt gaagacggca agctgtttat aaatgaggaa
     4441 gaggcagttg caataagaac gattttcgac cagtatgtaa atactacgat aggagccaat
     4501 gggatatcta aatacttaga gaatcatgga attagaaaaa tcccaagaca gaatggtaag
     4561 aatcctttgt ttgatgcagg tcttataaga aagatattaa agaatcctgt atataatggg
     4621 aaaatagcat ttggaagaag aactttagaa aaagttcatg gtacaagaaa tgaatataag
     4681 caggttgaac aagatgaata tctaatatct gaagggatac atgaagctat agtttccgat
     4741 gaagtttggc aagctgctca ggttaagcta aaatctcaag caaagaaata tgagcatgtg
     4801 aataaaggaa aagatacacg cacacacttg ctttctggaa ttgtaaaatg cccgatatgt
     4861 ggagtgggaa tgtttgggaa caagtgtatc aagaaaaaga aagatggcac aaagtataaa
     4921 gatttttatt actatggttg taaacatagg cagatgataa gaggtcataa gtgtacattc
     4981 agtaagcaaa ttagagaaga attgttagat gatgctgttg cagaggtgat tgtcaagata
     5041 gtaagtaatc cgaaatttgc ttctatgatg caagaaaaaa tcaacatgaa ggtggatacc
     5101 tctgaaatag aaaaagaaat agataattac caaaaggaat tgagaaagag tcattctaca
     5161 aagtttaagc taattgagga aatagataat ttagatgttg aagataagca ctataagaga
     5221 aggaaacagg atttagatga tagactatat cgtatgtatg acaaaataga tgaattagaa
     5281 tcatcactaa ttgatgcgaa agcaaagaaa cagactattg aagctgaaaa acttacagga
     5341 gataacatat ataaggttct gatctatttt gataagctct ataaagtcat gaatgatgta
     5401 gagcgtaggc agttaatttc agctttgatt tctgaaattc aagtttatga agaaaaacaa
     5461 tctaacggac aatggctaaa atccattact tttaagctac cgattataga agaaaatctc
     5521 aacatagatt tggacaatga tgaacaagtt gaatgtgtaa gtttattaga gaaacgtagt
     5581 taatcctcaa aaggttcccc aaactttttg agtcccactg acgcatcacg ctgaggcggt
     5641 atcactgctt gtacgagttg aagcatcagc gaagtaaaag tagatgttca gccaatgcga
     5701 cgaggtgaga ccgaaggtcg ataaggtgtg ttctgggtat aggactcgta aagtaagtag
     5761 gaaatatgat gagatgatac agagagcctg aattggtcag gtgacgtgct tatttacatt
     5821 agcctgataa tgaaaatgga gagattatcg atggttatat tggaattgta ccaaaatgat
     5881 tattctaaag atttagtagc atttgattcc atagaagatg ggaaagcctt tgtagctcaa
     5941 atcccgggat acactctgga aacagaagat ggttttgaag tggagtattt taatcctaaa
     6001 aacataccgg attatatgga aattattttt aacggaaata ttgttccttt atctaaattt
     6061 atgttcgatc ctgaggaaaa tgtaaacatt atttggaaag agatttcaaa tttatccctc
     6121 aaaaatgata gagtgatcga aggatattca aaaattgatg catatgtcgt taacaaccat
     6181 gaagttaaag cctatgtcga aacaagagaa acgaactatc gtaaagcaaa agacttctta
     6241 gaaagccgcg gatatgaaat cgacagaagc tttttcggaa gtgaagacgg tgaagcgatt
     6301 ctttacagaa aaaaagggat cgaagtttgg catttcttgt gtcacttaga cccaatgttt
     6361 gtagagattg aagatgtaga aggatatgtt aaagaagaag ttggagagat tcaatagtca
     6421 accaaagttc cttgtgagta tatacctttg ctagtaaaag agtcaaaacg ttataacgaa
     6481 ggggggaaga aaacccttga gtgtaagtct ttttcttgtt tagagggaaa gtattagagt
     6541 agccgctcat aatttatact agatttgata actgatttga gacagatttt atttctataa
     6601 atattgtgaa aattttttaa taccaaagat ttaaagttac tgtgttaaaa atcctctcca
     6661 cttttaaact aatgtattat aaaagccagt tgacacaagt gttacacctg tgatagaatt
     6721 aacttgaggt gatgaaaatg gcaaccgata aaaatagaat aatgattagc ttggatgata
     6781 aaaatctaga gaaacttgaa aatttagtag aagatgctag agatagaagg ggaatgcgac
     6841 taacaaagtc ccaggttatt gaattactcc taaataccgt tgattatttc gatgatatta
     6901 tgggggctat ttactcaaaa aaataagagc aaaattgcta ttatttttta caaattggtg
     6961 taacactagt gatataggag tgatgaaatg gttgtttata ttagacaaag taacttacca
     7021 agtgaggttt caattaataa atacaatgct caagtaggtg cctacttaca aggagaagaa
     7081 gctgttttat atcaatcttt ttctgaaata aaagagttaa caagtgaaga tatagttgta
     7141 gattatataa tggagactag agcattacta aaaatgatgg gcttaaacgt tccggttcat
     7201 gactatccta ttgagcttaa agagttttat ggtcgaaaga tttatgctgg tattttagga
     7261 gagattgtga atatacctga taattgggga aaatttatta agcctaaagc tggttcaaaa
     7321 gtctttactg gaagagttgt taatggaacc catgatttaa taggtattgg tctacctttc
     7381 gactatccta tatggattag tgaggttgta gaattcatag ctgaatggcg ttgttttgtg
     7441 ttagatggtc gcgtattaga tgttcgaccc tatacaggtg attatcatgc acaatttgat
     7501 gcaagtgtaa ttgatgaagc gatatcatgt tggaaagatg cgccaatagc ttatggacta
     7561 gatatcggtg ttactcgcga tggcagaaca cttgttgttg aagtaaatga tggttatgca
     7621 ttgggaaatt atggcctatc tcctttaaaa tcaatcaatt ttcatagagc taggtggaaa
     7681 gaaatggtaa aaccctattt tgaaaaaaat gaaattttta aaatccaaca ggatgttgtt
     7741 ttctaaaata aatatggtat ataaccaata taaaaagcat caaaatgaac aaggaggaat
     7801 ctgatgcttg gagcaattat tggagatatt gtcggttctg tttacgaatg gaacaatatc
     7861 aaaacaaagg actttccttt atttcggaag gactgctttt ttacagatga cacggttatg
     7921 acctgtgctg ttgcagaagc aattatgaat ggtggacaaa aagacgattt cattgacgcg
     7981 atgaagaaat atggcagaat gtatccgaat gctgattacg gtgctcggtt taatgcatgg
     8041 ctaaacagcg ataaccgtga gccttataat agctttggga atggatcagc tatgcgtatt
     8101 tctccatgtg cttggatcat ggactgtggt ttttatgcga aaactggtat gtggccatca
     8161 tctagaggac ttacgagtct ttctgcagag gtaactcata atcatccaga aggtgtcaaa
     8221 ggcgctatgg ctacagctga tgctatcttt ctatgtcgtt tttactttgg tggttattgt
     8281 agagagtacg agcaatcaat taacgacaat cctacagagt gtaaaagacg aattaaggat
     8341 tatatagaaa aagaatacga ttacaatcta tctcaaactt tagatgaaat ccgtcctaac
     8401 tatcgtttta acgaaacatg tcaggaaact gtccctcaag ccattatcgc ctttcttgaa
     8461 agtagagact tcgaagatgc gataagaaat gccatctcac ttggtggcga cagtgatact
     8521 ctcgcagcaa tcacttgtag catagcagag gcagcttacg gtattcctga ttggatcaag
     8581 gataaggcct attcttactt ggatgaaccc ttaaaggatg tagttaggcg atgggaaaat
     8641 agaataaaag cgtattaatc tccagtacgt cagatttctc ttttctgtat tttcattgta
     8701 taataggatt acatttactt gcatacgacg aaatgtaaac atttctgttt aaaattaagg
     8761 ataaaatcaa tgaaaaaagc aatggtaatt atcaacccta cttctggtgg cgagaaggct
     8821 ttggattaca aagaaaagct ggagaataaa gcaaaagaat actttgaata tgttgaaacc
     8881 aaaattaccg aaaaagcgct ggatgcaaca cattttgctg aagaagcttc tcgtgagcag
     8941 tatgatgcag tggttgtgtt tggtggagat ggaactgtca atgaagtcat ttcaggtatt
     9001 gatgagagag actacattcc taagttaggg attatcccag gcggtacggg taacctcatt
     9061 acaaaacttt tggaaatcaa tcaagacatc gatggcgcaa ttgacgaact ggattttgat
     9121 ttaaccaata agattgatat cggtaaagca aatgacaact attttggtta tatctttagt
     9181 atcggttctc tgcctgaggc gattcacaat gttgaaatag aggacaaaac aaaattcggt
     9241 attttaacct atgctgtaaa taccatgaag tctgtcatga cagatcaggt ctttaacatt
     9301 aaggttgaga cagaaaatgg aaattatgtt ggtgaagcta gccatgtttt ggtccttttg
     9361 acaaattact tcgctgataa gaaaatcttt gaagaaaaca aggacggcta tgccaacatt
     9421 ttgattctga aagatgcctc tatattctcc aaattatccg tcattcctga tttattaaaa
     9481 ggggatgttg tcgcaaatga taatatcgag tatatcaaag cgcgtaatat taaaatctct
     9541 tcagatagtg aattggagtc agatgttgac ggagataaat cagataacct acctgtagaa
     9601 atcaaagtcc tagctcagcg agtagaagta ttttcaaaac cgaaagagga ttagtatata
     9661 gagaaagcct tttttaaggc tttttgtata ctttaaaaga tagttccttt aacaacggac
     9721 attccttgca aatagtttac aaaaatagta tactggattt attgagtttg aaaacgtttg
     9781 cgtaaaattt gaatgaatac tttaggagac aaattgatgg aattgagtgc tatttaccat
     9841 aggcctgagt cggagtatac ctatctttat aaggataaga aactccatat tcgaattcga
     9901 actaagaaag gggacattga aagcatcaac ttgcactatg gggacccttt tatctcagag
     9961 atacagaagg tcaaaatatt ttgtatggcg ataaagggtg tgtggaaaat tctctagaaa
    10021 atcttcatgc aattgggaat ggatttaagt tgccttatct tcatgagatt gatgcctgca
    10081 aggttcctga ctgggtttca aatacggtat ggtatcagat atttcctgaa agatttgcca
    10141 atggcaatgc tctattaaac ccagaaggga ctttagactg ggattcatct gtcacaccta
    10201 agagcgatga tttctttggt ggtgatttac aggggattat tgatcatatg gattacttgc
    10261 aagacttggg tattactgga ctatatcttt gtcccatctt tgaatctaca agcaatcaca
    10321 agtacaatac gacagattac tttgaaattg accgtcattt tggagacaag gagacctttc
    10381 gggaactggt ggatcaagcg catcatcgtg gcatgaaagt catgctggat gcggtattta
    10441 atcatattgg ttcgcaatct cttcaatgga aaaatgtcgt caaaaatggt gaacagtctg
    10501 cttataagga ttggttccat attcaacaat tcccagtgac aactgaaaag ctagttaata
    10561 agagagactt accctatcat gtttttggtt tcgaggacta tatgcctaag ctaaatacag
    10621 ccaatccaga ggtcaagaat tatcttttaa aggttgcgac ttattggatt gaagagttta
    10681 atatcgatgc ttggcgtttg gatgtggcta atgagattga ccatcagttc tggaaggatt
    10741 ttcgtaaggc agttttagct aaaaatcctg atctttatat cctaggagaa gtctggcata
    10801 catctcagca ttggctaaat ggagatgagt tccatgccgt catgaattat cctttatctg
    10861 atagtatcaa ggactatttc ttacgaggaa ttaagaagac agaccagttc atcgatgaaa
    10921 tcaattgaga gtctatgtat tacaagcagc agatttcaga ggtcatgttt aatctcttgg
    10981 attcacatga tacagagcga atcctgtgga cggccaatga agatgttcaa ctggttaaat
    11041 cagccttagc ctttttcttt ttacaaaaag gaacaccgtg catttattac ggaaccgagc
    11101 tagccttgac tggaggacca gatccagatt gtcgtcgttg tatgccttgg gaacgtgtat
    11161 caagtgacaa tgatatgctg aactttatga agaggctgat taagattcgg aaatacgcgt
    11221 cagtaatcat ttcgcatggc aagtatagcc ttcaagaaat caaatctgat ctagtagctc
    11281 tggaatggaa atacgaagga cggatcctca aagtaatatt caaccaatca acagaagatt
    11341 atcttttaga gaaagaagca gtagcactag caagcaattg ccaagaattg gagaatcagc
    11401 ttgtcatctc tccagatgga tttgtgattt tctaaaaact agttgatgaa gattatggta
    11461 catttcatat cttatatagt ataataaggc tagttactaa acttgtaaag gagaacttaa
    11521 atgaattgta gaggacatga aacaagacaa agaattgtta gagattttga agtttagcct
    11581 aaagcacata ttaagctgtt agcaaatcaa caaaaacata gtgatgcagg agcaactatt
    11641 gaagatgaat attatgtatt tatcgctgag agtaaaattg atggcaagaa ggaagttatt
    11701 cagtgttgca tgggtgcggc aagggatttt ttagaactaa ttaatcacaa agggctacct
    11761 ctttttaatc cgcttgtagg tgattctcat gtaaataata gacaagaata tgacaataca
    11821 gggagtggaa atttacaacc tgaaaagtgg aatgaaactg caaagcagct ttataatatt
    11881 ataatgtggt tgattatttt atggaatgct aagccggata cacctttatt taattttaaa
    11941 gacgaagtaa ttaagtataa aacatatgag ccttttgaaa gcagtataaa aagagtaaat
    12001 actactataa agaatggtag taaagggaaa actctgactg agatgattaa tggctacaga
    12061 gcggataacg atattagaga tgaaatttgt aactttaata ttctgaaaaa taaaattcgt
    12121 gatatgaaag accaacaagg aaatacaatg gaatcttact tttagttatt gttgaatttt
    12181 gggtattcta taaaatatcc taattgagat ttaaatagta gactatacaa tatagttaaa
    12241 atatcagtaa aaacaacact ttattgaggt attggatacg ctttgctaat agcctaataa
    12301 tcacatgtgg agtgttgcta caacgaaaaa ggtgataatc cttgatttca agctatttta
    12361 taagcatttt gtctttgtag ataaaggcaa ttttgacaat aaaaatccta aaaggtgaat
    12421 cgttatagat gtatttgtag atatcgtttg cgcatcgaaa aaattaatac aagaataaat
    12481 atttatggct ctttaggtga cttttataga agtaaagttt aggatagaaa aacaagaaat
    12541 aacgcaccat ttttggtgcg tcatgctttt ttatgctata atggatttat aaaaataaag
    12601 gagtttgcta tgattggaaa gaacataaaa tccttacgta aaacacatga cttaacacaa
    12661 cctgaatttg cacgaattat aggaatttct cgaaatagct tgagtcgtta tgaaaatgga
    12721 actagttcag tctctacgga attaattgac atcatttgtc agaagtttaa tgtatcttat
    12781 gtcgatattg taggagaaga taaaatgctc aatcctgttg aagattatga attgactttg
    12841 aaaattgaaa ttgtgaaaga aagaggtgct aatctattat ctcgactcta tcgttatcaa
    12901 gatagtcagg gaattagcat tgatgatgaa tctaatcctt ggattttaat gagtgatgat
    12961 ctatctgact tgattcagac aaatatctat ttagtagaaa attttgatga aatagagaga
    13021 tatagcggct atttggatgg aattgaacgt atgttagaga tatctgaaaa gcggatggta
    13081 gcttaatgga aatccaagat tatactgata gtgaattcaa acatgcttta gcaaggaatc
    13141 ttcgttcact gacaagagga aaaaagtcca gtaaacaacc tatagcgatt ttgcttggag
    13201 gtcaaagtgg tgccggtaag actacaattc atcgtattaa acagaaagaa tttcaaggaa
    13261 atattgttat catagatggt gatagttttc gttctcagca tccacactat ttagaactgc
    13321 agcaagaata tggcaaagac agtgtagaat ataccaaaga ttttgcagga aaaatggtag
    13381 agtctttagt aacaaaattg agtagtttga gatacaatct tttgatagag ggaactttac
    13441 gaacagttga tgttccaaag aaaacagcac aactcttgaa aaataaggga tatgaagtac
    13501 aattggcctt aattgcgaca aagcctgaat tgtcgtatct aagtactctt atccgttatg
    13561 aagaactgta cattatcaat ccaaatcaag cacgcgcaac tccaaaagaa catcatgatt
    13621 tcattgtaaa tcatctagtt gataatacac gacaattgga agaactggct atctttgaaa
    13681 gaattcaaat ttaccaacga gatagaagtt gtgtatatga ttcaaaagaa aatacaactt
    13741 cagcagcaga tgttcttcaa gagttactgt ttggggagtg gagtcaggta gagaaggaga
    13801 tgttgcaggt gggggaaaag agacttaatg aattacttga aaaataaaca attgatattt
    13861 ttaggagagt agaaatgaga gggtttaata acaagataaa gtctgtttat caagaactaa
    13921 caaattccaa agagaaattc ggtagctttc acaagacttt aattcatttg catacacctg
    13981 tttcttatga ttacaagcta ttttctaatt ggactgcaac gaaatataga aaaattactg
    14041 aagatgaact atatgatata ttttttgaaa ataagaaaat aaaagttgat aagacaattt
    14101 ttttagtaat tttgataagg ttgttttttc tagttcaaaa gaatatatta gttttcttat
    14161 gttagcagag gcaatcataa aaaatggaat agaaatagtt gtagtaactg atcataatac
    14221 taccaaaggt attaaaaagt tacaaatggc agtctcaatc ataatgaaaa attatccgat
    14281 ttatgatata catcctcata ttttacatgg agtagaaatt agtgcagcag ataaattgca
    14341 tattgtatgt atatatgatt atgaacaaga atcatgggtt aatcaatggt taagtgaaaa
    14401 tattataagt gagaaagatg gaagttatca acattcactg actataatga aggatttcaa
    14461 taatcaaaaa atagttaact atattgctca tttcaatagt tatgacattt tgaaaaaagg
    14521 ttctcactta tcaggtgcat ataaacgaaa aattttttct aaagaaaata cacgattttt
    14581 ggagtttaat attaactcga aagaatcttc gcaacaactt gatattctct ataaagaagt
    14641 tggtgtatta agtttgggac aaaaagttgt agccatgctt gattttttat tagcatatag
    14701 tgactattct aaagacttca gaccattgat tattgatcag cctgaagaca atctagacaa
    14761 tcgttatatt tacaggcatt tagttcagca gtttagagat gtgaaagctc aacgtcaaat
    14821 tattttagca acacataatg ctacaattgt aacaaattct atgacagatc aagttgttat
    14881 tatggagtca gatggagtta acggatggat tgaatcacag ggatatgtta gtgaaaaata
    14941 tataaaaaat catatcatca atcaattaga gggaggaaaa gattccttca agcataaaat
    15001 gtctatatat gagacggctt tatcagagta gagtcagaaa aagtaggtta gaaatttagc
    15061 ctactttttt ctttgttcga caggcatagt gtacatctga ggtccaagtc ctctgtggat
    15121 atttgctgca gatgaaacca atagcgactc ctaagcctga atatcgtgag gtagggggga
    15181 taggaaggaa ttagcgaaat caaggttcta caaacagaat cgtgacttga agccatatat
    15241 agcggatgag gaactctaaa atccaaatag gtgtcgtaac ctatatacgt aaattacgag
    15301 agtaaactag gaaagatgta cggcttattc cgtgagcgtt taggacgtag tacaacaaat
    15361 catgggagtc agctgaacac atagtattga agaaatttct gtaatggaaa tggagcgaag
    15421 aagtgaacaa ttaaatgaat acctctctaa ttaaatttgt caattctaat tcctggtatg
    15481 aaaagacagt gacctaaaaa tgtaaacgat gggagctgat tataaatata ggacggtaca
    15541 tgcagtggtg ttagagatta gtccctactt gatttgtgat aacttcccca actttcttct
    15601 gctatacttt tctcaacttt taaaaatcca actaagaatt ttacctggga gtttgggggc
    15661 gtagccacca agttatctta tggttagctg tcaaaactgg aaggttttgg ttagctggcg
    15721 atatgatttt ttgggtattg tgaccacaat gcctgagctc gcaaagaccg aacaaggact
    15781 ttaagaaatt tcccgtatga cacacggggt cggggtttac ccgagaaagg atgaaagtga
    15841 ggaaaagaga tgtctgaaca gtaccgtgac attcgaaaag aggtaaatct aaccgcagat
    15901 gagctaaaac agattgaaaa aatgatggag gttgataatt atcgtcactt ttcatcattc
    15961 gtcagggata aaattttgat gactgatgac aaacagttag ctgccaaaga atggttttcc
    16021 ctttggcagt ctcaaaagtt tgaacagatc agtcgagatg tgcatttggt tttgattatc
    16081 gcaagagaga atcaccaagt gactcaagaa cacgtgtcaa tcttattgac ctgcgttcaa
    16141 gaattgattg cggaagtcaa tcaagtacag tcactcagtc gtgggtttcg tgaaaaatac
    16201 atgagatagg aggctactat ggtttatcgt tatcgtacca atctcaaaaa agtatttcta
    16261 acagattcag aattacatca attgaatgag cgaatcgata agagtcactg tcaaaatttt
    16321 tcagtctatg ccaggaaagt gttgctgaat cccaatatgt catttgtcac cattaatacg
    16381 gatacctatg accagttagt atttgaattg agacggatcg gaaataacat taatcaaatt
    16441 gcgcgtgcta tcaatcaaag ccgtctgatt tctcaggaac agttacaaga attgagtaaa
    16501 ggagtcggag agttgatcaa ggaagtggac aaagaatttc aagtggaagt gaaaagattg
    16561 aaggagtttc atggtagtca ctaagcattt tgcgacacac ggaaaaaaat atcgtaggcg
    16621 tttaattaag tatatcctca atcctgataa aacggacaat ttgaaattag tatctgattt
    16681 tggtatgagc aattacttag actttcctag ctatgaagaa atggtagaaa tgtacaatgt
    16741 caactttacc aataatgaca agttgtacga atacagaaat gaccgacaag aaaaacacca
    16801 acaaaatatt catgcccatc acctcattca atcattttct cctgaagata atctgacacc
    16861 tgaagaaatt aaccgcattg gttatgagac cattatggaa ttaacaggag gccgttttcg
    16921 tttcatcgta gcgactcata cagacaaaga tcatattcat aatcacatct taatcaacgc
    16981 cattgactgt aattcagata aaaagttgat atggaattat gccttggaac gaaaccttcg
    17041 tatgatttca gaccgcattt ctaaaatggc tggggcgaaa attattgaaa agcgtttctc
    17101 ttaccgtgac tatcaaaaat atagagcgac tagccataag tttgaactaa agcaacgtct
    17161 ttattttttg atgcagcagt caaaatcctt tgatgatttt ttagaaaaag cagagcaatt
    17221 acatgttcat attgatttta gtcagaagca tagtcgattc atgatgacgg atcgggcaat
    17281 gacaaaacca attcgaggac gtcaactcag taaacgagat ttatatgatg aagatttttt
    17341 tagaatgcat tttgccaagc aagagattgc aagtcgttta gaatttttgt tgaactgtgt
    17401 caattcttta gaagcgttac taacaaaatc aaaagaattg aatctaacca ttgacttaaa
    17461 acaaaaaaat gtaatcttta tacttgaaga aaatggaaag caattcagtc tgagtcataa
    17521 aaaaataagt gatgagaaat tatatgatgt caattttttt caagattatt ttaaaaataa
    17581 ggaagtaggt gtttcagaag gaatagaaaa tctacaggca cagtaccgtg cttttcaaga
    17641 agaacgagat aaggagaagg tatctactga agaaattgag gaagcctttg agacatttaa
    17701 ggaaaaacga gatgccgttc atgaatttga agtaaaactt acagaacacc aaattgagaa
    17761 gttagttgat gaggggattt atatcaaagt gtcctttggt ataaatcaga gtggtcttat
    17821 tttcattcct aactatcaac tggatattat ggaagaagaa aatcagaaaa aatataaagt
    17881 ctacattcgt gagacaacct catattttgt ctataacaaa gaacatttgg ataagaatca
    17941 gtatatcaaa gggagaacct tgattaggca gctaaccaac gatagtcgag taataccata
    18001 cagaagaccg actgttgaaa gacttcaaga aaagatttct gagattagcc tcttgattga
    18061 gttaactgag acagataaga aataccaaga cattaaagac aacttggttt ccgaaatagc
    18121 agagctagat ataaaactga ctcaaacaaa tgaaaaaatt gccaccttaa ataagatggc
    18181 ggaagtactt atcgattcta agagtgaagg ttcgggtagc caaaaactag ctaggcatga
    18241 attttctaaa ttgaacatga cagaatcaac aactttagaa caagtcaatg aagaactttt
    18301 gaagttacaa caggaatttg gtaatgttct tgatgagtat gagaaaacaa taagaaagct
    18361 tggacaatta tttaaggttt ttgatgagtg tatcaataaa gaaattatga atgaaatata
    18421 aatcagactg aagacaaact caaatttttt tggatatctt ttctgtttat ggttgccaat
    18481 atcggtttaa cttctaaaac aaacattaat aaaaatgcat tcaaagacga ttttacctat
    18541 tttacgatta cgcttcgacc ccaaatcatt aaagttgtct atgctctatc attgcatcac
    18601 tggacttgtc aagagttaag ataattcgga gtccactgaa aaagtcatcg tatgatggta
    18661 tactaaagat gaggtgatgg tatgcttgat aatcgatgtt agtccctatt ctactctgtg
    18721 tgatattgtt gttcccaaaa ctcatttttt acgacagcta atggaactct gtgattttag
    18781 ttttatttat gacgagctgg aaaagaatta tcaacctgac ttcggatgtc gttcctactc
    18841 tctccttatc atgatgttca agtatctctt attaaaagac atctataagt tgtccgatgt
    18901 ggatgtggtg gagcgctcct tttctggtat gaccttcaaa tacttccttg gtctagctcc
    18961 tgttattgaa ccgtcctcat tgactaaatt ccgaaaactt cggaacaaag atgaacgatt
    19021 acttgatttg ctcatcgcta aatctgttca gattgcgata gagctcggtc tgattaaaag
    19081 taacattctc attgtggatg cgactcatac caaagttcat tacaatcaca agaaacctca
    19141 agaagtcctc cgagaacgct caaaagcctt gcgtaaaacg atttatcagt attcggaata
    19201 tatcaaggca gaatttccta gtaagcctca ggaagatact ctagtagctg aattaagata
    19261 tacacaagaa gtaatatcag tccttgagaa gcatgacgaa ttgactggaa taccagctat
    19321 ctcacaaaat tcaattacct taaagaagct gtagaggatg acttagagca cttggaatcc
    19381 tctgtcaaag aagaagcaag aattggacat aagtcagccg atagttcctt ttacgggtac
    19441 aaagagcatt ttgccatgac cgatgaacgg attattactg cctgtgtggt gacatcgggt
    19501 gaaaaaagtg atggtcctgt tttagaagaa ctctatcaca aatctaagga taatggcgtg
    19561 acgattgaag ctattgttgg agatagggcc tactctggga aggataatat gcaatttacc
    19621 aagaaagaac gtgtgcattg agtcgctagg ccatatccaa ctatttcaaa aggctttcgt
    19681 aggaaggaag atgagttttt ctataacaag gacgcaggtc tctttgtttg tccagaaggg
    19741 catatggcac taaagaaggc aaagacagga agaaggacgg ctcaggaaac ccactatttt
    19801 gacatcaagc actgtcaaat atgcccttca aaagtgggct gttataaaga aggggctaag
    19861 tctaagactt atttgatacc ccttaagagc gatgaacata ttttccagaa gaggtttcag
    19921 gaagcgccct attttaaaga aaaggccaaa catcgctaca agatagaagc caaaaatgcg
    19981 gaacttgaaa acagacatgg tcttaatgta gctagagcac caggtctttt aaacatggag
    20041 ttacaagccg ccacaaccat atttgtggtt aatatgaaga ggattataac tctaataaac
    20101 caaaaataag gaaaagcaaa gaggaatcta tccaagcagg agatagatcc ctcttttttc
    20161 attttagttg aactgtagag cttacttttt cagtggactc gatgattagt gactattttt
    20221 ttcaaactct attggttatt ggtaccctaa tgccgaatgg agatatttag gattgtaata
    20281 gatttcaata tatttaaaga tttcgttcaa tagttgcgaa attggcatca ttgacaagtt
    20341 ctctttttat gttttgtaaa aggattccat gggtgcatta tcatatggat ttccttttcg
    20401 actcaggcta gacttgcatc ttttctgttt aaggagttct tgaaatctag ctccagtata
    20461 ttgagatcct tgatcggtat ggccgactag ttcttatttg agattttctc tatgataagc
    20521 ttgattgaaa acattcgtta ccaacttatc ttgcattcga tttcccattg cctaaccaac
    20581 aatttttctg ctataaacat atatataatg ataaataaag agtacctgct tttgtcggaa
    20641 tataagttaa atcccccagc cagatttcat ttttaccttt tgtttgaaaa cactgattaa
    20701 tcaaattggg tcgtgttaat gaggaatgcc gacggctata gtacttgtat ttatagcgga
    20761 ttcctttagc atagagacaa atatgacaat attttaaata aaatgattga caacgctttc
    20821 ttttattgat ataatgaaaa tgtaatatgt atcaaattga tcaatcaact atcttgttta
    20881 tcacttctta agaggacgat gtcatgaaaa gaagaaaaat atattccttt tttgcgtagt
    20941 tacaattgca tctagtttgt ttctccctac agttttagc
//
LOCUS       DBEROT010000037        20706 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.37, whole genome shotgun sequence.
ACCESSION   DBEROT010000037 DBEROT010000000
VERSION     DBEROT010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20706
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.37"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..315)
                     /locus_tag="ACL8CG_001637"
     CDS             complement(<1..315)
                     /locus_tag="ACL8CG_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGS1344194.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDD"
     gene            complement(437..2395)
                     /gene="ftsH"
                     /locus_tag="ACL8CG_001638"
     CDS             complement(437..2395)
                     /gene="ftsH"
                     /locus_tag="ACL8CG_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGS1344195.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMSGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2411..2953)
                     /gene="hpt"
                     /locus_tag="ACL8CG_001639"
     CDS             complement(2411..2953)
                     /gene="hpt"
                     /locus_tag="ACL8CG_001639"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGS1344196.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2957..4234)
                     /gene="tilS"
                     /locus_tag="ACL8CG_001640"
     CDS             complement(2957..4234)
                     /gene="tilS"
                     /locus_tag="ACL8CG_001640"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGS1344197.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(4231..5499)
                     /locus_tag="ACL8CG_001641"
     CDS             complement(4231..5499)
                     /locus_tag="ACL8CG_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGS1344198.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5492..5614)
                     /locus_tag="ACL8CG_001642"
     CDS             complement(5492..5614)
                     /locus_tag="ACL8CG_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGS1344199.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            complement(5619..5987)
                     /locus_tag="ACL8CG_001643"
     CDS             complement(5619..5987)
                     /locus_tag="ACL8CG_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGS1344200.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5980..6246)
                     /locus_tag="ACL8CG_001644"
     CDS             complement(5980..6246)
                     /locus_tag="ACL8CG_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGS1344201.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6314..9838)
                     /gene="mfd"
                     /locus_tag="ACL8CG_001645"
     CDS             complement(6314..9838)
                     /gene="mfd"
                     /locus_tag="ACL8CG_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGS1344202.1"
                     /translation="MVTLLDLLSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKRKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNK
                     KDYEILEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9839..10408)
                     /gene="pth"
                     /locus_tag="ACL8CG_001646"
     CDS             complement(9839..10408)
                     /gene="pth"
                     /locus_tag="ACL8CG_001646"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGS1344203.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10479..11594)
                     /gene="ychF"
                     /locus_tag="ACL8CG_001647"
     CDS             complement(10479..11594)
                     /gene="ychF"
                     /locus_tag="ACL8CG_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGS1344204.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11714..12880)
                     /locus_tag="ACL8CG_001648"
     CDS             complement(11714..12880)
                     /locus_tag="ACL8CG_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1344205.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKGGATVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQIRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS"
     gene            complement(12976..13428)
                     /locus_tag="ACL8CG_001649"
     CDS             complement(12976..13428)
                     /locus_tag="ACL8CG_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGS1344206.1"
                     /translation="MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQ
                     NDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETME
                     NIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK"
     gene            complement(13428..14432)
                     /locus_tag="ACL8CG_001650"
     CDS             complement(13428..14432)
                     /locus_tag="ACL8CG_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGS1344207.1"
                     /translation="MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNS
                     QLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQL
                     SISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTA
                     LEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARA
                     TMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAR
                     EKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
                     "
     gene            complement(14581..15537)
                     /locus_tag="ACL8CG_001651"
     CDS             complement(14581..15537)
                     /locus_tag="ACL8CG_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1344208.1"
                     /translation="MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTI
                     TGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMF
                     FNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISK
                     NNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINS
                     LNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFC
                     VTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD"
     gene            15694..15927
                     /locus_tag="ACL8CG_001652"
     CDS             15694..15927
                     /locus_tag="ACL8CG_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1344209.1"
                     /translation="MEQWTLKACRVNAGYTLRQVAKKVNKNFQTVSKYEKDSTYIPFE
                     LLKELSAIYQVKLDNIFLGDSTKKIELNKRELQ"
     gene            16017..16643
                     /locus_tag="ACL8CG_001653"
     CDS             16017..16643
                     /locus_tag="ACL8CG_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HGS1344210.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIKTWEAKPKHAHSTMNNLLLKAVTDMNAKQLVKSRGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSV"
     gene            17095..17547
                     /locus_tag="ACL8CG_001654"
     CDS             17095..17547
                     /locus_tag="ACL8CG_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344211.1"
                     /translation="MTETTYENLTRRINRISAEMQEIGEKNGLSRLSLLASQTKFIKE
                     ELSRLLWIELPELNDSHKIEAVSKSTTGMFFHPGIFEMDAMRQAFFKRQAMHFFENEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            17544..17744
                     /locus_tag="ACL8CG_001655"
     CDS             17544..17744
                     /locus_tag="ACL8CG_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344212.1"
                     /translation="MTLDLDNMTQAEFDKQMAEIKERNPNIFQLISDFLDRKVTPEEV
                     DEFLKMERAEQVEYIKNYQARV"
     gene            17746..17961
                     /locus_tag="ACL8CG_001656"
     CDS             17746..17961
                     /locus_tag="ACL8CG_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344213.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPDYGRYIQLAGVNVWGGME"
     gene            17958..18251
                     /locus_tag="ACL8CG_001657"
     CDS             17958..18251
                     /locus_tag="ACL8CG_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344214.1"
                     /translation="MSYTMNLYPDIEKIPDETYFTKEIFLATCLNNTIRIAVARGVLT
                     SQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            18232..18573
                     /locus_tag="ACL8CG_001658"
     CDS             18232..18573
                     /locus_tag="ACL8CG_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGS1344215.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            18566..18841
                     /locus_tag="ACL8CG_001659"
     CDS             18566..18841
                     /locus_tag="ACL8CG_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344216.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG"
     gene            18981..19841
                     /locus_tag="ACL8CG_001660"
     CDS             18981..19841
                     /locus_tag="ACL8CG_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HGS1344217.1"
                     /translation="MTIYEARGFQSNLVYPFDKMEPFQYIERFKPLVVPESADPEEYK
                     RTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVAVTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            19894..>20706
                     /locus_tag="ACL8CG_001661"
     CDS             19894..>20706
                     /locus_tag="ACL8CG_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5906 domain-containing protein"
                     /protein_id="HGS1344218.1"
                     /translation="MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVTEKV
                     AMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDV
                     RIKPREWPQIKLMVRTLAKIRKPLESANLVPVKNGIIDLRTKELLPFSPKYVITSKIS
                     TAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYG
                     DGNNGKGTFQRFLINLIGESNISALKPAQFGEKHNLETLVGKVCNIGDEAPNE"
BASE COUNT         6457 a         4004 c         3516 g         6729 t
ORIGIN      
        1 atcatctagc cagagacctc cctcacttat acgatgactg agctcaccca cttcttcata
       61 gggttcttta tcgtatctac gcttctgact ttcctgctta cggatatagt ctaaaattcg
      121 atttcgaaac ttggttttga aatatttcct taaacgtgga atatcgtcta ccagtccttc
      181 ttctctacta atcaattcat gtaagcagag catgccttct tggtcccaat ccgacaattc
      241 ccataaatga aggtaatatt catttctaca cttatacaca gtcccttgga cttcttcata
      301 caattcttta atcataattt tcccctttct agatacagtc taacagatta gaaaacacat
      361 ttgttccatt ttctccattc tgttcccttt agctcctaaa ctgcacaaaa aagagaggct
      421 ccagcctctc tcagggttat ttttcgtcat tcatttttga ctttacttca tcataggata
      481 gtgcatgaga ttcctcttct actgcttcag gcatctttcc tgtttcgtaa agagctttaa
      541 tttgtgtact atccaatgtt tcgtatttca ataatgcttc tgcaattaac ttgtgagttt
      601 cacgatttga ctgaataatt tcagcagctt tatttcgtgc ctcatttaat aatgaacgaa
      661 cctcttcatc aatttcataa gctgtttgtt ctgaaattga tttttgagga ctctgtgcac
      721 cagacatagc atggtttcct tcatattgta ctgggccaag tttttcactc ataccgtact
      781 ctgtaaccat tgcacgcgcc atttgtgtcg cttgttcaaa gtcgtttgaa gctcctgtag
      841 tttggacatt aaagataatt tcttcagcta cacgtccacc cattaagcca gccaattgct
      901 ctttcatatc ttctttagat agaagcattt gatcctcttt aggaagtgca atcatgtatc
      961 cgcctgcacg gccgcgtggt acaattgtaa ccttatggac aacgcgagca ttcgacaaga
     1021 ctagaccaac aatggtatgt cctgcctcat ggtaagcaac caattctcgt tctttttgtg
     1081 aaactgtctt atctttctta gaaggtccag caataactct atcttctgct tcatcaatat
     1141 ctgaagcatc aattatcgat ttattgcgac gagcagcaac taaagctgct tcattcaaga
     1201 cattctctaa atcagcacca acaaagcctg gagtttgttg agccactaat ttcaaatcaa
     1261 catcttctgc taaaggcttg ttcttagcgt gaactttcaa gattgcttca cgacctttaa
     1321 catcaggacg gccaaccaat acttttctat caaaacgtcc tggacgcaaa agggcaggat
     1381 caagtacatc tgaacggttt gtcgcagcga tgacgataat cccttcattt ccctcaaaac
     1441 catccatctc aatcaaaagt tggttcaagg tttgttcacg ttcgtcatta cctccgccga
     1501 gaccgactcc acgttgacgt ccaacagcat caatttcatc gataaagatg atagctggtg
     1561 ctgctttttt ggcatcctca aaaagagagc gaacacgact agctccaact ccgacaaaca
     1621 tttctacaaa gtcagaacct gagatactaa agaatggaac acctgcttct ccagcgactg
     1681 ccttagcaag caaagtctta cctgtccccg gaggtccctc caaaagaaca cctgctggaa
     1741 tacgggctcc aagttttgtg aatcgttttg gatcttttaa gaactcaaca acttcaacta
     1801 gttcttgttt ttcttcctca gctccagcaa catctgaaaa tcttacttta atatcttctt
     1861 tatttgctgc tttagcctta ctacgtccaa aactcattgg attacggcca ttgcctcctc
     1921 ccatatttcc catcatagag aataggaaga agaatagaat tccaaatggc acaatggata
     1981 cgagtagatt aatccatata ccacttgaac tttcatgctt aacagttact tctgctttat
     2041 ggtcagtagc aagtttttgc aattctgata cggtagtatc tgcaggaaga atagtgctgg
     2101 taaatttctc taccttagta acagatggcg tgaaaaactg aatgcctgtt ccttctttac
     2161 ttgttttagg atttttatag acaccagaaa cttcgataac actaccattt ggttggtaag
     2221 ttaattcttt tacattacca tcggtaattt cttgtaccaa ctcagtatag ttgatttgct
     2281 gacttcctcc tgagttattc ccagaataga aatactggaa tcctgtcaca aggaaaaaga
     2341 taaataataa ccatagaaaa ggatttttaa ttaaaccatt attttgtttt ttcattaaag
     2401 attattcttt ctaatttgaa tacacttcct ctttcaatac tccaatataa ggaagattac
     2461 gataattttc tttgtagtct aaaccataac ctactacaaa ctcatttggg atagtaaagc
     2521 aggtatagtc tgcctcaatt tctacaacac gtccttctgg tttatccaac aaggttgcaa
     2581 ttttaacaga agctgcttct ctttctttaa acatatctcg caaattcttc aaagtttgac
     2641 ctgtatcaat gatatcttct acaaatagaa catgtcttcc tttgatatct tgagtcacat
     2701 cttgtttaat attgataaca ccactacttg ctgttccacc atggtagcta gaaaccatca
     2761 tgaagtccat ttcaatatgt gtatcaatat gtttgaccaa ttcagccata aaaggaatag
     2821 atccttttaa aatcccaact aagattggat tttttcctgc atagtcttta gttaattgag
     2881 cacctagttt tttagctgct tctgtaattt catcgtgtga aacgaggact tttttaatat
     2941 cgttttctaa cattttttac ctatctattt tttctatata aagtacagtg ttcattatat
     3001 catttttcgt ttttttactc aaattattgg tcgcaattcc caaaattgag acaatttcac
     3061 caaattgctc aataataaga gcagagtttc tcttttccat agggattttc aaatcaataa
     3121 ataaacgtct gagttttttt ctatgcccat tttgaatcaa aacatctcct gtttttcgat
     3181 gacgaatgtg tatggatgtt tcacgtgaaa caggtatttg ttgaattgat tcaccttcta
     3241 atggaagtcc aaaggaaaat aaatatcctt gataagctac ctgattttga tagtgtaaca
     3301 caagttcatc ttccttttca tcagcctgcg gactgatttt acaaatctga aactgttggt
     3361 actcttttat caattcatag ccatttttaa tcggatgacg atactggctt ttagatttta
     3421 aaatctgctg aacttcagca aactgagctt ttgtaagatt caaatctgga aaacgattca
     3481 gataagtttg aagtaaaact ctttgtgtag actcagagta agaaaataac tgctgtaaat
     3541 cttccacatt aatattgtta gataattcag ctattgccaa atcataatct aaaatttcat
     3601 tgccaatgcc taagattgca tccctaaatc gaggattttc tttttccaat tctggtaagt
     3661 aagagtttcg aatacgattt cgaaaataat gattctcctg atttgatgta tcttcaaagt
     3721 gaaaaattga tggaaagtct tttttctgaa aatgcaagaa gggacgaatg atttctatct
     3781 ctccgactac ttgcttctcc ttaattcctg atagatagcg caagcgagtt cctcgaatca
     3841 agcgcatcaa aatcgtttcc acctgatcat cagcatggtg ggcagtgact aaagctgtcg
     3901 cacctgtctt tttcataacc tcttgaaaaa aatcataacg aaaatttcgt gcacgcgctt
     3961 ctgaaaattc tcctgaaaaa ttgctgatat aaataggaag ctctgcttca gcagccaact
     4021 tccttaattc cttttcttcc caatctgatt caattctctg cttatgattc acatgagcca
     4081 gaatcaattc aatctctaac tctttttgat aagtagacaa taccttaaat agaaacatag
     4141 aatctaatcc accagaaaga gctagaaccg ccttagcatg ctttttgaaa tatcccttct
     4201 tgagaaaatg atttaaaaaa tctggttccc tcattttaga acctcataaa catccttggc
     4261 tatcttagaa atcgtatcat aatcagaatt cttagtgaaa atagaaagaa taaatggaga
     4321 atctgcatag acaacacccg tatcatgctt aaattcatcc gcatctccaa ttttatgagc
     4381 tactttaaca gaaacacctt tggcaattcg ctgactatca aaatctgttt tagtcaaaga
     4441 ctctagcaca aatccatttt gattataaat agcttccata aacttcccgg ccatcttaga
     4501 agaaatcaat ttttcttttg gatcccaatc atctcccata atggcagaca tcttggattt
     4561 gaatgtggca tcagattggt ttgaaatgta atatcccaat agattatgag ctacattatc
     4621 agattctttt gatactttcg taattaaatc ctttaaagaa tattctttat tatcttcttt
     4681 tttaggaaga ctaccacttc cctctggttt ataagaacct ggaaaatcat tgactgcaga
     4741 tacgtatttt acagtcgtat ctaactgata aagaccctca tttatttttt cttgcgtata
     4801 atagagatag gagagtttca aaacgctggc tgcatacatc ttttcatctt gattgatacc
     4861 agcttctttt ccagtagtca gttgcttaac ataaatagag aaagaatctt tctgatattt
     4921 ttcagataac atttcttgaa ctttactcat ccgattatct tcttcagaag ttgattcttt
     4981 agctacccat ccagcctgat caatatgtag aaattctctt ccttctacaa acatggtctt
     5041 gtcgattgat acttgcgaat aagctgataa ggatgatttc acttctttta aatcataagg
     5101 actattgtac agtttaaagt cagattctaa ccatactttt tttattgttg gagttacctc
     5161 tgattgatca tataaaaatc gtttgtccgc agctataaat tgatgatttg atagcttaaa
     5221 tactggaatt ccttgtttat ttaagcgcca ctcggttatt tgaaaacttg ttttgggagt
     5281 caatttccca gattccacta ctaaatcttc attcgcataa acaggaacct ctccataaac
     5341 catgggagaa cttaattttt ctctaaaata aataccaaag tcagattgtg aaaggtaata
     5401 aatttctttc gaagtataga cgacttcttt ttctgtgcta acgacttttg aaatggtcaa
     5461 aaaacttggt aacaacaaaa taattaagaa tttacgcatt cttcctttcc ttttcttctt
     5521 gtaaacgcaa taattgattt ttatcagcca attcttccag cttttcatct gacaaactca
     5581 aaaattgctc tattacgtct aataaatttt ccattttatc acctttgaag caagtcagga
     5641 atcgtataaa ctttttccct cgacttagaa taatagtact tcgctcgtgt atatttagca
     5701 gcataatctt catctttcaa cttggtagca aatgctgtct ccttatcctt ttcatcactc
     5761 aaagtttgat actgagtttg caagtctgct aattgctgac gtctttggag taattgctga
     5821 taactctgcg ctaaattaaa agttggcaag ataaataata gcataatcaa aatcaatacc
     5881 cctcccataa aacgattccg tttttgtcgt tctttcatca ggtagcgacg acgttggtat
     5941 tcattttgaa taaaagaatt attcaattgt acaatatttt tagacatttt cttctacccg
     6001 tgtttcactg ataatttcat acattcctgc tgcatcttct ttttttgtac tatctttcat
     6061 ctctagtact tttacaagca gcaacttatt gccaaagcga atttcaactt ggtcattaac
     6121 tttcaagtcc gttgaacttt tggccaagat tccattaacc ttgattctac ctttatctgc
     6181 tacttccttt gcgactgtac gacgcttgat aattcgcgat acttttaaat atttatctaa
     6241 tctcatcctt attacctcaa tttattattg taccattttt atctattttt atctatttta
     6301 tagaagaaaa atatcaaatg gaattttctt ccttaaactc ttttatctct aataaacttt
     6361 ctccaaaaat cagcagacct tctaaaattt cataatcttt cttattttgg acatcaaata
     6421 caagctccat taatccctta ttctcagcga tgcctgcttt taagttcgtt acggataaag
     6481 ctttaaaata atcttgagct aaaaacaatc gttgagtgac tttttcaaat tgaattgtaa
     6541 ttttattatc ttttctttta ttatcttttc tttccacacg ttgaacaaag accttgtcca
     6601 agtatgattt aaccaaacca atctctaaaa gataggctac tacatctggg tattctccaa
     6661 aacggtctat caactcctct tgtaactctt cataattgac acggttgtca atttgacgaa
     6721 ttttcttgta aatttcaatc ttatgtcgtt gatcagaaat ataagtatca ggaagatagg
     6781 catcaatttg caaaatcaac tcagcattcc ctttggttct tgtgttagcg ttagcattac
     6841 cgtttcgttt agcaatagct tcctctaata actgcgaata caattcaaaa ccaacagaat
     6901 caatgaaacc agactgggat tttcctaaaa gatttcctgc tccacgaatc gaaagatctc
     6961 gcattgcaat cttaaagcca gagcccaatt ctgtaaatcc tttaatcgct tctaatctct
     7021 tttcagagac ttcactgatt gatttttctg gacgatacat gagataagca taagcaatac
     7081 gattactacg accgactctt cctcttaact gatataaggt tgacaagccc atatggtccg
     7141 cattttcaat aaataaagta ttagcatttg gaatgtccac ccctgtctca ataatagtag
     7201 tcgtcaccaa gatatcgtat tgtccctcaa taaagtctaa tagagtattt tccaactgga
     7261 cttcactcat tcgaccatga acatatccaa tcgaagcctc cggaatcaac tcctgtaatt
     7321 ctgaaacctt ctgaacaatt gtgtcaactt tgttgtaaag ataataaact tgacctccac
     7381 gctccatttc acgcaagaca gcatcacgaa tgacactatc attcttttcc aaaacatagg
     7441 tctgaacagg atagcgatta gtcggcggag tttcaataac agataaatct ctgattccca
     7501 gcatagacat atggagggta cgagggattg gcgtagcggt caaggttagg acatccactt
     7561 gtttcttcag ttctttcaaa gtttccttat gcttgacacc aaatcgctgt tcctcatcaa
     7621 taatcatcaa gcccaaatca gcaaacacaa catcttttga caaaacacga tgtgttccaa
     7681 tcaaaatatc gacttgaccg tttttcaatt tttcaagtgt tgcagtctgc tcttttttac
     7741 ttctaaagcg actcaacaca tcaatattaa ctgcaaaatt ttggaatcgt tccttaaaat
     7801 tcgtatagtg ctgttgcgct aaaaccgtcg tcggaactag aatgacaacc tgtttgtgat
     7861 cattgactgc tttaaaggct gcacgcatag caacttcagt ctttccaaaa ccaacatccc
     7921 caactaaaag tcgatccatt ggctgagaag cctgcatatc cctcttgatt tcctcaatac
     7981 tacgaagttg atcatccgtt tcaacataag ggaaagcatc atcaaaggca tcttgatcat
     8041 catcatcagc tgagaaagca aaacccttca actgactacg ttcagagtag agtttgatta
     8101 aatcatcagc tatatcctct acctggttct taaccttttg cttggccttt ttaaaatgac
     8161 cgtcatttaa tttattgagt tttggagctt taccatcact tgaaatatat ttggacagta
     8221 gatgaatctg ttccacgggg atagaaattt gatcaccatt ttggtattgg acactgacat
     8281 aatcgcgatg aattcccttg atttcaatgg tttcaattcc tagatattga ccaatcccat
     8341 ggatatgatg gacaacatag tccccttttt caagttcatt gtaatctttt aatctctctg
     8401 catttgaaac atgttgtctt cgaaaacgac gctttaattt cttttgaaaa atctcatgtt
     8461 cagttatcaa taaaatcttt tcatctacaa aatgaaaacc atgtctgaga ttaccctcta
     8521 ttaagtttac agattcttta cagatacttg tcttatctct agaatccaat ttaatctgat
     8581 attcctctaa catatcctcc aatgttttac ttcccattga attgctagac tgcagaataa
     8641 tggtgtaatc cattttttta tatcgttcaa tttcttcttt tagaaaagaa aactgattga
     8701 aaaattcctg cataggatat tgattgaatt gataaatttt gtcaaatttg agatttccta
     8761 aacccttttg aagattagag aaaaaggtca ctggactttg ttttttatag atttgttcaa
     8821 tatcagaaaa atactgcata tcagaaaatg ctttactatt ctgtaattct tctgtaaagt
     8881 actgcgctaa ttctctttca aagacttcat actgattcat caatttttga taatcatcaa
     8941 agaatattgg agtatctttt tcaatataat caaagacagt ccatgtctta tcatagcaca
     9001 aagataaaaa cttccgagag tctgcatgac tttgtttttg gtgaaaactt gaaagaattt
     9061 cttctaggta tgatttcaaa ataggtgata aagtttttga aatttgtttt tctaaagctg
     9121 actgtcctcg ttgataatcc ttttctctca aaagcatatc actagctgga aagatagtga
     9181 gttctgtctt attttctttc gataattgtg tttctacttc aaatgacctg ataccatcaa
     9241 tttcatcacc aaaaaactca attcgacaag gttctaactg ggatatttca aaaatatcta
     9301 aaatatctcc tcgaagacta aattcgccct gagtttgtac ttgagtaact tttcgatagc
     9361 cattttcctt taactgatgg ataaacgcgt gttgatcata ttcttcacca actgagattt
     9421 ttacaatact atctttgaat gcattgggag acggtaaaat caatcgactt gctgcgatat
     9481 tacaaactaa aatccctttc ttagatgaat cagtcaaaaa acgcaaggct tcaacccgtg
     9541 aaataatttt ttcctgtgaa gacatcaaaa actccaccat aggagcatca tctaccaaaa
     9601 atggatagac gagttcctca cccaagatag atataagatc actaacaagt ccttctgctt
     9661 ctccataagt tgacgtcaat aacacaatcc tatcttcttt ttctaaactg cttgcaattg
     9721 caagagcctt agtagatgtt gataaaccaa gtattagttg tcttttctta tctgttaaat
     9781 tttgatgcca ttttttaatc tgatcatttt ctgagagtaa atctaataag gtcaccattt
     9841 atccgttata cctctgcatt gttttctcaa aatttttctc ttgtaaatag tagtttacag
     9901 aatcgtcaac tttgtcaaca gactgtaaaa taccgatata atcatccctg tcaaacttac
     9961 tcaaaacatg atgaacaact gacataccat ttttaggtct tccaattcca atcttaacac
    10021 ggttaaagac ctgagttcct atatgttgaa taatagactt gataccatta tgaccacctg
    10081 ctgagccttt tgctcttaaa cgaattttcc caacttccat gtcaagatca tcgtaaatga
    10141 taagtaaatc gtcaatatcc aaaccatagt aagttaataa agcatgaact gcttttccac
    10201 tttcattcat aaaggtcgtt ggtttaacca gataaatttt ttctccattt aggaaaaagg
    10261 atgctaggtc agcttgaaat atcttatcgt gtgtaaaagt gacattctgt ttcttcgcta
    10321 gttgatcaat caacataaaa ccaacattgt gttttgtttc aaaatattta tcccctggat
    10381 ttcccaaacc tacaagtaat ttggtcattt atttttcctt tcaaaagcca aaagggttgg
    10441 aatttttttc caacctaatt gacaccattt attaattttt agacattaaa gcggaattcc
    10501 atgatatcgc catcttgaac gatatattct tttccttctt cacgcaagcg tccagcttct
    10561 tttacggcct tttcagatcc gtatttcact agatcttcat atgacatggt tactgcacga
    10621 ataaagcctt tttcaaagtc tgagtggata ataccagctg cttgaggagc cttcatacca
    10681 cgtttgaaag tccaagcgcg aacttctttt tcaccagctg tgaagtaagt tcccaatcca
    10741 agcaagtggt aagctgcacg cgtcaactta tctacacctg attctgtcaa accaatggct
    10801 tcaagaaact cttttttatc ttcatcatcc aattcagaaa tttcttcctc agcacgcgca
    10861 gaaataacga ctacttcagc attttctgtc gctgcaaatt cacgaatttg tttgacatag
    10921 tcgatagagt caggttctga aaccacatcc tcgtccacat tagctacata aagaactggt
    10981 ttagtcgtca aaaggaaaag acctttgaca accttttgtt cctcatctgt aaattcaatg
    11041 gtacgagctg atttcccgtc ttctaggact ggtttaatct tttgaagaac attgaattct
    11101 gctactgatt ctttatcttt ttgcgtacgt gccatctttt ctacacgcgc atatcgtttg
    11161 ttcactgatt ctaagtcagc aagaattaat tccagattaa ttgtatcaat atctgcaagt
    11221 ggatctacaa aggcgtcttc acgtccttgc tcgcgcatta cattttcatc atcaaaagca
    11281 cgaactacgt gaacaatcgc atctacttca cgaatattgg ccaagaattt attccctagc
    11341 ccttctcctt ttgaagctcc ttttacaatc cctgcaatat ctgtaaattc aaatgttgtg
    11401 ggaactgtct ttttaggagt tatcatttca gttagttttt gtaggcgttc atctggaact
    11461 tccaccattc caacatttgg atcaatagtc gcaaatgggt agtttgctgc ctctgctcct
    11521 gcttttgtaa ttgcattaaa tagtgttgat ttaccaacgt ttggcaaacc aacgatacct
    11581 gctgtcaaag ccatatttct cattctccgt tttcatttca atccctaata ttataacaca
    11641 aaaagggaaa acttgctaaa attccttgat atagctattt cccataactg aaataataat
    11701 tttatggact tttttaggaa ctttttaatt tttcaatagc tttttcataa aatgaagtag
    11761 catttttctg attgtctttg gataggtggc tataaatatc catggtcata gaaagttttg
    11821 catgaccgag ccgtatttgt atctctttgt aaggtagtcc agcattgagc aagatactag
    11881 catgagtgtg gcggaaggcg tggaacgtaa aacgagggca tccagcacgt tccaaatgtt
    11941 ttactaacct gaaactaagc attctagcgt ctatatgctt atcaaagcta ttagagaata
    12001 ctttctcata ggtcaacccc atttctttcc ctatttggga ttgtcttgct ttatagagcc
    12061 gtagcatgag caccgtctta ttatccaagt caattaccct aatacttgat ttagtcttag
    12121 ggccagtgat ttctttgata atatttaacg ttttatttac gtctagtgtg ccgtttttta
    12181 ggtcaatatc agaccatttg agggctaaac actcacgaat acgcaaacca gtcgctaaaa
    12241 gcgtcttata tagcaccgta tcgtagaaat ttttgtaagt gtttggcagc tgctccaggt
    12301 aagtcaagaa tttttttaag ttatcatcat ccagatattt cagtttttgc ccttcttttt
    12361 ccttacgacg tggcacgata acatcacggg cagggttaaa ggggatagct tgcaaagata
    12421 cggcatattt aagtatgcgt ttgtttagag agtgaaggag cggatattct tggaatcctt
    12481 tgcctagttg attatagtct tttgcccatt gattgacttg cttttgaatg attgggggcg
    12541 tcagtttatc cagcctataa tttccgaaag ctggaagtag atatttatct attttgaatt
    12601 tggtacccat taaggtcgat tttttaaccg tatggcagta cgtttctagc caattctcca
    12661 ccagttcggc gtaagtcttt atctccaccg ctttatatac tgtagcccct cctttttcaa
    12721 agtcgatttg agcctgtagc gctttggctt tgagttctct cttggttcgc cctgatatag
    12781 tcgtcttgac tttcttacct gttacggtat cgataccaag gtagacgcta gagcgataga
    12841 ctgtagaccc gtcttttttg gtgtattctg ttattttcat gatgataaac ctttctaaaa
    12901 tacatcagca ggcaagctat tattaaaaag gttttagatt atggtttata tcatgttgag
    12961 cttacgggaa agattttatt tgttattttc ttcagctaaa gctatctgta caagtttttc
    13021 ttttactttt tcagtgagtt cctcatagta gagaattgaa gaaataattt cttttaaaaa
    13081 attgaaatcg attaacccca ttgctaccca taagacaata ttttccattg tttcgataaa
    13141 gaagggaatg aggtaatcaa ggtgattgat tgttaaaaat ttaataccga agacaatgct
    13201 acttctctta tttccatcat tgaacatatg aaattgaact gtattaaata ctagcactgt
    13261 aagttttgtt tcaaagtctg gatagtaatc gtcattctgt aagtgttcaa atacactaaa
    13321 tacccttccc ttatctttaa caccgtgtaa accacctatt ttctcaatta cttcaatgtc
    13381 gtgtagtaaa attgcttctt cagcagaaaa ataattgatt ttatccatta tttatctctc
    13441 aatctttcaa aaacttggcg gtgttcatca atttgttccg aaagtgattt actttgttcg
    13501 ccaataaatc tttcaaaatc ttcttcagaa attggacgga tatattctgc taatttctca
    13561 tgtttggcat tcctgaaaga tagatcccta ctagccattt tctctctggc atgcattaaa
    13621 tggggttctt gcattgggtg atttgctaat ctctgaatta tctcgattac atcagtatta
    13681 gttagttttt gatttgaaga cttactcttt tgttcaatct cataagcaac ccctttctca
    13741 aaactagcaa taactataag tacctcacta tacattgttg cgcgagcatt atcattttta
    13801 ttcaatttca gtattttttt atattctgat gctctttctt taaagattgc tttgtaaatt
    13861 tcattcgtta attgaccata tttaaaatta cttccagaga catacttatc aatggcattt
    13921 gtaaatattt ttctagcatt atcttcttct aatgcagtcg atagataatt tttgtcacgc
    13981 tggtttataa attttacatg gccaccagtc ttctcagtta acacattaat gacaatatca
    14041 agtagggtat ttcttacttg cttagctata tcactattgg ttaacaacat agcaaaatta
    14101 agcaatgttc tgaacgatga gatacttaat tgtgtaactt tgctaccgac atttgtgtcg
    14161 gtagcaaaag cattttcttt aaatttagct agtttttctc cacgtaaagt gtgataacca
    14221 ttttcagtaa gctccgtttt atgagcttca acaagtcttt caatagttcg aatgtcgact
    14281 tcgaaaaagg tagctagctg agaatttgta aaataaaaag tatcctcaaa gtagaaacca
    14341 ggtactttta aaatctcttc agctttttgt aatgctaaag aattatttaa aatattttgt
    14401 ctttctattt gtgaggttgt cagatcagtc ataatttctc ctttttgtcg agttaatttg
    14461 ccaataactc ccgatatttc aagagtttta ttttattttc gtgtcgttag agtatattag
    14521 aaaatcttga actccgcgaa tacacgcgct tcaggattgt tgaacattgt ggcgcgtggg
    14581 ttagtcgctg aagtgttccc tgatttcttc agctaaatca ttcaagcggt tctgaatacc
    14641 tttatagtaa tcaaattcaa tggtgtcaat gatgtcactt ttttcagtaa atatcttgtt
    14701 ttttgtaaca caaaagctat tatttgtatt attgtgaaca aggtcattta tctcattttg
    14761 aacagaagat attttccttt gtaagcaata gcctaagatt tttcgatctt gaatacctat
    14821 tttttcaatt atttcattca cttcaaagac aactgcccca tagctatcaa ttttattgtt
    14881 aaggctattg ataagattag aaatttcaga atgcacatag gaggtattga gagcttgctc
    14941 acgttcaata acgtttatta aacgtgtaat atattcgtta gtaatcatgg tgagtacatt
    15001 attataagcg tactccctag cttcgcgctg tttggaaagt agtagagcct cattattttt
    15061 tgagatatct gataaatcaa gtccgttgaa aatttcaaca ataccagggt ttattattga
    15121 agactgaaga acgcgaccca aaacaccctg gtcaaatgct atttttcctc gaatgtactc
    15181 catattcata taatcttttt taaagctaag tatttctttg attttattga agaacatctc
    15241 aaaaaccttt tctctttgat tattatctag caactctttt agtgtgctgg ttgaaactgt
    15301 atcaataaac cgcagatcta ggaaagattt ttttacgttc aaaaaatcag ctattttttg
    15361 taaattccca gcggttggta aagattttcc ttttacatat cccgtaattg tacttttagg
    15421 aatatctaaa gcgttatgaa ggtcaatttg tctaacccct ttttgttcca taagaaggtt
    15481 gagccgttta gagaagtatt ctctattttc aagatcttga ggactatttt tagccatgac
    15541 tttaaccctt tcagttgtaa gttatacatt gattataaca caaaataaaa acaaagtacg
    15601 aaaataaata aacttttttc taaaaacact tgactaagta cgaaaataat agtactatta
    15661 acttatcact tttgaaagga attgttagat tatatggaac aatggacgtt gaaagcctgt
    15721 agagtaaacg ctggttatac tttgcgacag gttgctaaaa aggtaaataa gaattttcaa
    15781 actgtctcca agtacgaaaa agatagtaca tatataccgt ttgaactttt aaaagaattg
    15841 tctgcaattt accaagttaa attggacaat atttttttag gagatagtac gaaaaaaata
    15901 gaactaaata aaagagagtt gcaataatga gagtattatt ttaagtcaat ggtggcagaa
    15961 atcaaaccag acataacaat agatgaatta ttttatagct agaaaggagc aaaccaatgg
    16021 aactagtcta tatggacggt aaaaaagagc cgtatacact gagcagtatt gtggcagagt
    16081 gtgcagaagt caagcacaga catttgaaga ttttgctaaa taaacaccga gaggacttcg
    16141 agagtttcgg aaaggtgcaa tttaaaattt caccttcaga aagtgggcaa aatgtacggg
    16201 actatatttt aaatgaacaa caagcaacat tgctgatcac ttacttacga aatacagaac
    16261 ccgtaaaaga gtttaagaag aacctagtca aagcattctt tgaaatgcgt gaggaacttt
    16321 ctaagtttcg tatgcagagg gcgctagaaa agccaaaaag aaaaaccttg catgacagta
    16381 ttaaaacatg ggaggcaaaa cccaagcacg cgcatagcac catgaacaac ctgttactga
    16441 aggcagtaac tgacatgaac gctaagcagt tagtaaaaag ccgtgggggc tataatggca
    16501 ttgatagctt gaccagtgac gagctggagc aataccaggc atttgaggat atggtaatag
    16561 ccatgattgg cttgaatatg agttatcagg aaatcaaagc tatggcattc agaaataaaa
    16621 aaacacgcca aagaagcgtg tgagagcaac aaaaaaggct tagcaataac cacaccgcag
    16681 agcctttcac actaacacta aaacgaattt aacaaaaagc aggcaagcta ttatcaaaga
    16741 ggttttagta aagatttata cctagattat agcatattta gggcaatttg accatacgga
    16801 gagcgccaac tctttaaact ggtactttct cacgctttca atttggcgag tctgagcgtg
    16861 aggctagtac ttacaagaaa aaactgtata agaaacaact caaaaagccc cacgctcaga
    16921 agtttggcga ccgagagcat gaggctgtag gcaagaaaaa ctgtataaga aacaaccatt
    16981 caaaatcccc acactcgcca tcgctcaact ttgagtgtga ggatcagcag gtatagtaaa
    17041 aggtattaaa tggcccttag ggcaactaca caacatagaa acagaggtaa aaacatgaca
    17101 gaaacaacat acgagaattt aactagacgt ataaacagaa ttagcgcaga aatgcaagaa
    17161 attggcgaaa aaaatgggct tagtagactt tcgttattgg caagtcagac aaaattcatc
    17221 aaagaagaat tatcccgttt actttggatt gaactccctg aattgaatga cagccataaa
    17281 atcgaagcgg tctctaaaag cactacggga atgtttttcc accctggtat ttttgaaatg
    17341 gacgctatgc gacaagcatt ctttaaacgc caagctatgc acttttttga gaacgaagca
    17401 gagcaacagg cgtatataga acatgctgaa aaggagtatt tagaggctac tataacctta
    17461 aaagatattc tttttaactc taaaaatgga actcagagag taaataaaag ttgtcttata
    17521 gagaagtttg aggaggcaat gcaatgacac tagacctaga caacatgaca caagcagaat
    17581 ttgataaaca aatggctgaa atcaaggaga gaaatccaaa catttttcaa ctgatttctg
    17641 attttttaga tagaaaggta acacccgaag aggtggatga gtttttgaag atggagcgag
    17701 ctgaacaagt ggaatatatt aagaattatc aagcgagggt ataacatgaa tgagctagat
    17761 ataagtaaca cacaggctgc tgtcttaatc gtgattttga ttggcttact gctttattta
    17821 aaccaccgag accgcaaaaa aagcgcccaa attgagcgag aaaaccaaca gacgataaaa
    17881 acacctagcg aggatttaaa ccctgattat gggcgatata tccagcttgc aggagtcaac
    17941 gtatggggag ggatggaatg agttacacaa tgaatttata ccccgatatt gaaaaaatac
    18001 cagatgaaac ctattttact aaagagattt ttctagcaac gtgcttgaat aacacaatca
    18061 gaatagcagt agccagagga gtgctaacat ctcaactttt agacaaagaa actaaagaag
    18121 ttgtttgtaa aaccttggat acaatcatag aaaatcaaaa agctattttg caaggggtag
    18181 cgagcggaca aataaccttt gtaaataaaa gcaaaggaga ggaggggttg gatgagtcta
    18241 tcagagaatg acaagcgagt tttaagacta atcaaggtag gggctgagaa ctccataaca
    18301 gggtcagaaa ttagcctgac aaccaagcta acagaaagaa ctgtacgtga cattatcaag
    18361 cgtctagtag ttaagcacaa catccctatt gtaggggtta gatgtggcgt ttttagtggg
    18421 tactttattc cagcgaataa aggcgagtta ctagatggcg ctaaggcttt ttacaaccaa
    18481 gtacaggagg agagcaagcg cctagcggtg ttgatgaata gcgacctaga aagctacaaa
    18541 gaaaccttga aggaggtggg cggatatgtt tagcctaagc cgagaaagcg agcaagacct
    18601 agcgcatggc attctggagg tagtggaaag atacctggaa gcgcgtgaga aagtaccgcc
    18661 aagattgacc aagttaataa atagagttga actcaaagag gaattgaaaa ttagtgacaa
    18721 cacgctgaat aagtgggaaa gtcagggttt aagacgctat caaccgccgg acgatggtgc
    18781 tagaataata ttttatttag tggatgacat tcgtaggttt atgggggtgg agaatgggta
    18841 gatataacac acacccagcg caaggcggag gtcattatca tgacattaaa ttgtataagc
    18901 accgtggcag atctttggaa cagttccaag aacaaaagct actgaagaag ttaaaaaaaa
    18961 acgcaaaaag gggcgatagt atgacaattt atgaggctag aggtttccag agtaatcttg
    19021 tctatccatt tgataagatg gagccgttcc agtacattga acgctttaag cctttggtag
    19081 tccctgaaag tgctgatccg gaggaataca aaagaactca ggcgccatat tgtttaagtg
    19141 gtaaggttat gccggagaaa aacgggagtt acaaacgaaa caactccagt ctaatctatc
    19201 gggatttgat tttccttgat tatgacgata tacaggggac gactgaggac ttcatagaag
    19261 ccgtttctag cgctttgttt ggctactctt atatcttata cccgactatc aaacatagca
    19321 tagaaaagcc ccgttttcgc cttgtggtga aatctaacaa cgtgatgaac gaggcaacct
    19381 ataagcaggt agtaaaagag attgctgaca agattgggct accctttgac atggccagtt
    19441 taacctggtc acaactccaa gggctaccag taacaacagg cgacccagca acttatcaaa
    19501 agattgtaga gcatggactt gattatccag tccccaaggt tgaaccaaga gcgaagcaag
    19561 gaactactga gcgttataaa cctagagtaa gtggccagag gtcaatgact atgaggatca
    19621 ttgacacgct tttcaacgga tttggagacg agggagggcg taacgtggca gtgacacgct
    19681 ttgtgggatt actcttcaat aagtgggttg attgtgacct agagaccgcc tatgaactga
    19741 caaagatagc caatagtgtg acagttgaac cattgcctat tgaagagcta gaccgcactt
    19801 ttagcagtat agcacgggct gagtatagaa agagaggtta gaaccataga actagaagaa
    19861 ttagcaaacc taaaaagtga aatcatggag gtaatggagc aagaacaccc tcctagaacg
    19921 atgaaggagc ttgaaaatcg tatctttaaa gctggagaag aatggcgggc agaacatact
    19981 gaaactaagg taaatgagac cacaggggac gttaccgaaa aggttgccat gcctcagaca
    20041 ttcacagtag caaaaatact gagcgagatt gtcacattta cttttatcag caagagcaat
    20101 atacctgatt atagcctgct ctatatctat gatttagacg agggtatcta taccgctagt
    20161 aatgatctat tcaatctttt gtgtaagacc tttgacgtta gaattaaacc cagagagtgg
    20221 ccacagatta agttaatggt tagaacattg gcaaagatac gaaaaccttt agagagtgct
    20281 aaccttgtac ctgtaaagaa tggcattatt gacctaagaa ctaaggagct actccccttt
    20341 agtcctaagt atgtaattac aagtaagata agcacggcct accacgcgcc taaacgagtc
    20401 ccaacagata gagagggcaa aacttttgat gattggctaa actcaatcgc ttgtaatgat
    20461 agtgaactgg taacactgtt ttggcagatt atccttgaag ctattaaccc taaccatacc
    20521 cgaaataagt ttgctatctt ctacggggac ggtaacaatg gtaaagggac attccagcgc
    20581 ttccttatca atctgatagg ggaaagtaat atatcagcct tgaagcctgc acagttcgga
    20641 gaaaagcata acttggagac cttggtaggt aaggtttgta atattgggga tgaagcgcct
    20701 aacgaa
//
LOCUS       DBEROT010000038        20506 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.38, whole genome shotgun sequence.
ACCESSION   DBEROT010000038 DBEROT010000000
VERSION     DBEROT010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.38"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..808)
                     /gene="folK"
                     /locus_tag="ACL8CG_001662"
     CDS             complement(<1..808)
                     /gene="folK"
                     /locus_tag="ACL8CG_001662"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGS1344219.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALK"
     gene            complement(851..1405)
                     /gene="folE"
                     /locus_tag="ACL8CG_001663"
     CDS             complement(851..1405)
                     /gene="folE"
                     /locus_tag="ACL8CG_001663"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGS1344220.1"
                     /translation="MDRQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(1398..2708)
                     /locus_tag="ACL8CG_001664"
     CDS             complement(1398..2708)
                     /locus_tag="ACL8CG_001664"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS1344221.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKARNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENG"
     gene            complement(2710..3684)
                     /gene="folP"
                     /locus_tag="ACL8CG_001665"
     CDS             complement(2710..3684)
                     /gene="folP"
                     /locus_tag="ACL8CG_001665"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGS1344222.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASTIRLADEAENLDLKQYK"
     gene            complement(3779..4486)
                     /locus_tag="ACL8CG_001666"
     CDS             complement(3779..4486)
                     /locus_tag="ACL8CG_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1344223.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(4539..5957)
                     /locus_tag="ACL8CG_001667"
     CDS             complement(4539..5957)
                     /locus_tag="ACL8CG_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGS1344224.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAAGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            6147..6959
                     /locus_tag="ACL8CG_001668"
     CDS             6147..6959
                     /locus_tag="ACL8CG_001668"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1344225.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7298..8317
                     /gene="adhP"
                     /locus_tag="ACL8CG_001669"
     CDS             7298..8317
                     /gene="adhP"
                     /locus_tag="ACL8CG_001669"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGS1344226.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            8551..9540
                     /locus_tag="ACL8CG_001670"
     CDS             8551..9540
                     /locus_tag="ACL8CG_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1344227.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            9568..10371
                     /locus_tag="ACL8CG_001671"
     CDS             9568..10371
                     /locus_tag="ACL8CG_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGS1344228.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            10395..11306
                     /locus_tag="ACL8CG_001672"
     CDS             10395..11306
                     /locus_tag="ACL8CG_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1344229.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(11362..12696)
                     /gene="pepC"
                     /locus_tag="ACL8CG_001673"
     CDS             complement(11362..12696)
                     /gene="pepC"
                     /locus_tag="ACL8CG_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGS1344230.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(12808..13530)
                     /locus_tag="ACL8CG_001674"
     CDS             complement(12808..13530)
                     /locus_tag="ACL8CG_001674"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS1344231.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEIFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVEIFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILLASIA"
     gene            complement(13753..13983)
                     /locus_tag="ACL8CG_001675"
     CDS             complement(13753..13983)
                     /locus_tag="ACL8CG_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS1344232.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(13993..15234)
                     /locus_tag="ACL8CG_001676"
     CDS             complement(13993..15234)
                     /locus_tag="ACL8CG_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGS1344233.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(15256..15408)
                     /locus_tag="ACL8CG_001677"
     CDS             complement(15256..15408)
                     /locus_tag="ACL8CG_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344234.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(15429..15707)
                     /locus_tag="ACL8CG_001678"
     CDS             complement(15429..15707)
                     /locus_tag="ACL8CG_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGS1344235.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(15700..15963)
                     /locus_tag="ACL8CG_001679"
     CDS             complement(15700..15963)
                     /locus_tag="ACL8CG_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGS1344236.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(16065..20456)
                     /locus_tag="ACL8CG_001680"
     CDS             complement(16065..20456)
                     /locus_tag="ACL8CG_001680"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGS1344237.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFETKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFINKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
BASE COUNT         5860 a         4844 c         3965 g         5837 t
ORIGIN      
        1 ttttcaaagc atcatacaag ttgcggatcg gttgttttaa tatcggatgg ataaaatgag
       61 gcgcaatttc ctgtaaggac tcaaggacaa aaaggcgttc cgctatgtaa ggatgaggca
      121 atatgaggtc gtctgtataa aggatctggt cctccacaaa gagcaagtcc aaatcaatca
      181 aacgaggtcc ccaatgcact tctctcaccc gtcccagctc tgactcaatg gctaacaagg
      241 tttctaacaa gtcttgtgct ggtagccagg tttccacctc aaccacttga ttggcaaagc
      301 tatcctgctc cactccaccc caaggctccg tcgctaagac actggactct ttgagaatat
      361 ggatgccacg agctcgcagt ttgtcaatgg cttgcttcaa gtttgcttgt ttatctccca
      421 tattgcttcc tagggcgata aaggctcgtt gcttgcggcg atgaatggtt accgagcaag
      481 tatctagtga caaatgcacc ggtgcccaag gttttttcag ttccaacttc atttcttgga
      541 caagaggata agactcaaag gtacgttcca ccagtttata ggctaccgtt tcaatcaaat
      601 cttcactcgt ttcctgaaac caagtcgtcc actgctgaca caattctccg taatggacag
      661 aggctgttaa atccaagtct gtagctgcct tggtcatatc ataggatagg atggctgaaa
      721 cgacaaattt ctgccccaat tctttctcac taggaaaaag accatgatag gcaaacattt
      781 ccaaatcctt aatctgcagt tgatccataa tgattccttt ctagaaaaat ccgcttgaag
      841 cggattcttt ttatagcccc attaaacgat aagcttggtc acggagatcc ttatctgttt
      901 caaatagacc acgagctact gtcgtcaagg ttgcagtgcc tggttttcta acaccacgca
      961 tactcataca catatgttcc gcctcaatga caacaaaggc tcctttagca cctagatagt
     1021 ccatcaaggc atcggccact tcgatattca aacgttcttg aatttgtggt tttttcgaat
     1081 aaacttcaac cgtacgggct agcttagaca agcctgccac acgaccatct ggaatgtagg
     1141 caatgtgcgc tctaccataa aatggcaaga agtggtgttc acacatggta tggaaaaaga
     1201 tatccttttc taccaccata ttatcgtcaa taatttcaaa ggattttgac aaatgttcct
     1261 ctgctgtttg accaagacct gaaaaaatct cttgatacat acgggctaca cgagcaggtg
     1321 tttcctgcaa gccctcgcga ttagcgttct ctcctacagc ctcgataatc atttttacag
     1381 ctgcttcaat cttttgtcta tccattctcg ttcttcctct ccatcagata ggccctcact
     1441 tggctcaaga aatacaagga acctgtgaca atcctaactg tttgtttctc ttctttttta
     1501 tctgtcaaat tctgctctag aaaatcatgc caatcttggt agctgagatt tctagcctta
     1561 gctgcctctt tcagcacgct ttcatccgtc gcccgactat ccgcaaaatg tgttagagta
     1621 agctcggtat ctggcatggc tcccagcaag tccaacatat cctccaaggc tttggttttg
     1681 atacaagtga agaggatttc cttatgataa tccgcaaaac gttcttgcaa ggttaccaac
     1741 aaggccttga tagcatgggg attatgggct ccatccaaaa tcatcaaggg atctcttgac
     1801 acgatttcca aacgccctgg ccaacttgtt tcttccaagg cttgaccaag aaaatcattg
     1861 cttgctagct ctcgaccatc ttcttgacaa aaagtatcaa gtaaagctat ggccatccca
     1921 gcattctcta tttggtacaa accaagcagg ctagtctgga agcgaccttg tctgacagca
     1981 cttgtatagt caaagacttc ccctgtcacc acactttctt gatgacgaac ctgataatct
     2041 gtcccgtagg caagtctcgg cgcatctttc ccttccgcaa tgcggtcaat cacagtcaag
     2101 gcttctggag caatacgccc tgttaccaag ggcatccctt gtttgataat acctgccttc
     2161 tgctctgcta tggcctccaa ggtgtcacca agtagggcca catgatccaa gccaatagtt
     2221 gtaattcctg tcaaaatggg ctgacagaca ttggtactat ccaaaagtcc acccatgcca
     2281 acttccatga tagccacatc tacttgctct gaggcaaagt agtcataggc tagggctgtg
     2341 ataatctcaa actcggttgt gccctgtaaa ttggcgaccg cttctccctc cagcaaagac
     2401 tgatagtctg ccatgagagc ttctagcctc gcttctgaga tcgattcccc attgatgcta
     2461 atctggtctg tgtaatgaat gagatagggc gaactaaaca cgccaactct cagccctagc
     2521 ttttctagca tctttttcaa aaaagcaata gtcgagccct tgccgttagt ccctccgata
     2581 tggaggacct tgagtttgag atggggattg ccacgcaaag ctaacagttc caccattcgt
     2641 tccaagccaa aatgcggttg atccgtccgg tagttagcaa tccactgatt gttttcaatt
     2701 tctttcatct tatttatatt gttttaaatc taaattttcc gcttcatcag ccagacgaat
     2761 ggtagaggca atttcaactg ccatcctgtg actagctacg tcatgcacgc gcaccacttc
     2821 tacaccctgt ctcgcagcaa tactagttac atgagccgaa gccgtgtccc gatttcggaa
     2881 accaagctct gtctcaggat tgacttcaaa cccactttct tcaaggatat tgatgacaaa
     2941 tcgcttgcgc gacactccga gaaagattgg atagcccttc tgatgtagtt tatccaggtc
     3001 ccgtaaaagg aggagatttt ctttcttggt cagaccaaag ccaattcctg gatccaacag
     3061 gatattttct ggtgcaatac cagcttctgc cgctctcgct agtgctcgtt caaagaaagc
     3121 caccatcaag tcttcgattg gcaatgtttc aaagtcagct aactcttttt ctgtaaaggt
     3181 ttgaccaaaa ccaaaatgag ggaagataag cgaactagga tgctgaggtc gagccataac
     3241 tgggttaaac atgatgacca ctttcgctcc agctttagca accacatggg ccattttttc
     3301 atcacccatg agaccagtga tatcattaac tagattggca ccagcagcca aagcagcctc
     3361 tgccacctga cttttccaag tatcgataga aataaggaca tcgctttcct tgcgaatcgc
     3421 tttgatcact ggaacaacac gctggatttc ctcttctatc tcaacatagc tacttcccgg
     3481 ccgagtcgat tctccgccga tatctagcat actggctcct tctgcgatca acttccgagc
     3541 ctgctggagc gcctgctcaa gagcaaaaaa ttgaccaccg tccgaaaagg agtctggggt
     3601 tacattgata attccgcaaa taactgtctt tgcatgattg gctttacttg acatatcggt
     3661 cactccctca aggattttca tcatattatt tttctatttt accataaaaa gaaaaagatg
     3721 gacacgattg cattcatctt tccctagtag aaagaggtcg gttcctacat aaaaactttt
     3781 aaacagaaat tcctaatgtc cgactcataa tcaccacaag agccaacaaa cagaaagcaa
     3841 tcccattaac aatcatgtga agcaagatcg acatttccaa acgttgggtc ttgtaggctg
     3901 tccaagatag aactgtcgac atacctccat aaatcaataa agaaggtaaa ttacttggtt
     3961 gatgcaataa agcaaacaca atcgtaccga ctacaaatcc caagttctcc ttgcctcgga
     4021 aaatcttttt aggaacaatc ccacgacaca agatttcctc acaaatcgga gcaagcaagg
     4081 ctagcaagaa gaaactggaa atcaacgaac tattttgaac catatcatta atctgagact
     4141 ggttagctgt tgtcgtctca tttgacagtt gcaataaaat ggaaccaagt atatttgacc
     4201 cgacaataac tagataactc aagcccaaac gtgccaaatc tttagctcta aaaaaagaaa
     4261 aattaaaact agctaacttg gttttacgag ctcccataat aaatagagcc agaaccacaa
     4321 ttgaaaggcc agcaactatc agccctgact gtagcagggc tacttctttt aaagtcaaaa
     4381 tagaggtaac cactagggga acctgatata aaaggacggc aagtaaaaag accaaaatcc
     4441 agcctgcacg attcaacaat tctttccaca tatttttctc tttcatcacc tatctccttt
     4501 gtattaaaaa aggggggaaa tccccctggg tcattctatt ataaggccat gctgatgtag
     4561 ttaaggataa acaaggcatc caaaatccaa atcatggcat gaacatcttt aacttgacct
     4621 ttgacaagct tagtcaaagt gtaagtcaag aaaccaactg caatcccttg agtgatagag
     4681 tagctgaatc ccataaagat agatgtgaag aaggcaggaa ctgcttcaga catatcatcc
     4741 caatggatat ttttcaagct accaagcatc ataatcccaa cgataatcaa gattggagct
     4801 gtagccgctg ttggtacgat cgctagaagt gggctaaaga agcttgaaat cgcaaaacag
     4861 atagctacaa ccaaggctgt caaaccagta cgtccacctg caccgatacc agcagcagac
     4921 tcaacataag tcgttacgtt tgaagtacct gcaatggcac cgactgtcgt tccaatcaaa
     4981 tcagagtaaa gagccttatc caatttggct gattggtgat tttcaccatt tgtcgctaca
     5041 ataccaactt tttcacctgt accgatcaag gtaccaattg tgtcaaaaat atctgtcaat
     5101 gagaaggcaa gaatggccat cagagtttca ggcaagcgag ctgtatctga aaccaaagct
     5161 cccaaacctt ctgaaccaag agctgcacca aagattgtct tcaaatcttc aaaagctgca
     5221 ccaacatggt tattagcaaa atcgatacta gacaaatcaa ccaaaccagc tgcaatagca
     5281 agaacagttg ttgtcaagat agagagaata attccccctt taatcccttt gatgacaaag
     5341 aagatagtaa tggcaagtcc tgcaagagcc actaaaacag ctggattatt aaagctgacc
     5401 aatcctggaa ctgctgaaga gtttgctgca atcgttgctt gagctttgtc agccccttct
     5461 cctacaacag tatagttgcc tggatcaatc gtaaatttca aaagtccagc attcttaatc
     5521 cctacatagg caaggaagac accgatacca gctgaaatag ccgagcgaag ggcatttgga
     5581 atcgattcaa tgatcatttt acgaacattt gtcaaggtaa taaccaatga aataatccca
     5641 cagatgaaga ccatagctag ggcttcttgc catgaataac caagtccaaa tacgactgta
     5701 aaggtaaaga aggcattgag tcccatacct ggtgcttgag cgtatggcaa gttagcatag
     5761 aaggccatca tcaaggtacc agcaactgca ccgataatcg ttgcaagaaa cacaccctga
     5821 gcaggcattc ctgtttgtga aagtatttgt gggtttacaa agagaatata gctcattgca
     5881 aagaaagttg ttaaaccagc gagaacctct gtacgaacgt ctgtaccgtt ctcttttagt
     5941 ttaaataatt tgtccatcat caatctcctt ttaattttta cgaacaataa tagaattata
     6001 tcatttatca ttcacttttt caatgtcttt gtttgatttg tttaagaaat taatccaatt
     6061 tcattttttg tttggaatct gcttttctgc ctgctttctg ttataataga agacatctta
     6121 tctgaaaaca cactagaaag gtccatatga cgaaaaaaat tattgcagtt gacctagatg
     6181 gaaccctgct caactcagac agtcaaattt ctgactttac caaaaaaacc atcaaaaaag
     6241 ttgctgaaaa aggccatcag gttattatta cgacaggtcg cccttaccgt atgtcaaaag
     6301 atttttaccg tgaactgggc ttagacactc ctatgattaa cttcaacgga tcccttactc
     6361 atttaccaga ccaagtttgg gattttgaaa agtgtttgac tgtagacaaa aaatatctgc
     6421 tagatatggt tcaacgttca gaggacattc aagccgattt tatcgctgga gaatatcgta
     6481 aaaaattcta cattacaaat cccaatgaag aaattgccaa tcccaaacta tttggtgtag
     6541 aagctttcca gcctgaagat caattccagc ctgaattggt gaccaaggac cctaactgta
     6601 tcctcttgca gaccagagcc agtgacaaat atgccttggc aaaagacatg aacgccttct
     6661 accagcatca actttctatc aatacctggg gaggtccgct caatatcctt gaatgtaccc
     6721 caaaaggtgt caacaaggcc tttgctttgg actacttgct caagataatg aatcgtgaca
     6781 aaaaagattt gattgccttt ggagatgaac acaatgatac cgaaatgctc gcttttgctg
     6841 ggaagggtta tgccatgaaa aatgccaatc cagagctact cccttatgca gatgagcaaa
     6901 tttcccttac caacgaccaa gatggggttg ccaaaaccct acaagactta ttcttataac
     6961 ctatactgat actcaatgag aatcaaagag caaactagga agctagccgt aggttgctca
     7021 aagcactgct ttgaggttgt agatgaagct gacgtggttt gaagagattt tcgaagagta
     7081 tgaccagctt gcaagctggt ctttgtgctc ttttcacagt ctcatcaacc agttaatcga
     7141 ttgttctact ttttgtctcc aaaaccttgg aaaaggcttt cttttgtgat atacttcaca
     7201 tataaataca agagagctcg tcacactcga ctctgttgac aaaaaatcaa tccagtcccg
     7261 ttgtccctgt tctcggtcaa tatcaaggag gatagctatg aaagctgttg ttgtaaatcc
     7321 agaaagcact ggtgttgcta ttgaagaaaa agtactccgt ccacttgaaa ctggggaagc
     7381 acttgtagaa gttgaatact gtggcgtttg ccacaccgac ctccacgttg ctcatggtga
     7441 ctttggtcaa gtcccaggac gtgttcttgg gcacgaaggt atcggtatcg ttaaagagat
     7501 tgctccagat gtgaaaagcc ttaaagtcgg tgaccgcgtc agcgttgctt ggttctttga
     7561 aggatgtggc acttgcgaat actgtacaac tggtcgcgaa accctttgcc gtacagtgaa
     7621 aaatgctggc tactcagtag acggtggtat ggctgaacaa tgtatcgtaa ctgctgacta
     7681 tgctgtcaag gttcctgacg gacttgatcc agcccaagct tcttctatca catgtgctgg
     7741 agtaacaacc tataaagcta tcaaagaagc aaaagttgaa ccaggccaat gggttgttct
     7801 ttacggtgct ggtggacttg gtaacctcgc tgttcaatac gctaaaaaag tattcaatgc
     7861 tcatgttatc gcagtcgata tcaacaatga caaacttgcc cttgcaaaag aagtaggcgc
     7921 tgacattgtg attaacggcc tcgaagttga agatgtagct ggactcatca aagaaaaaac
     7981 tgatggagga gctcattcag ctgtcgtaac tgctgtgtct aaagttgcct tcaaccaggc
     8041 tgttgactcc gttcgtgctg gtggtcgcgt cgtcgctgtt ggtcttcctt ctgaaatgat
     8101 ggaactcagc atcgttaaaa cagtcctcga tggaatccaa gtcatcggtt ctcttgtcgg
     8161 aactcgtaaa gacttagaag aagccttcca atttggtgca gaaggtctgg tagccccagt
     8221 tgttcaaaaa cgtccagtag aagatgctgt tgccattttc gacgaaatgg aaaaaggtca
     8281 aatccaagga cgtatggtac tcgacttcac ccactaatct aatagaaacc tattttcaaa
     8341 gttggaagct tcttccaact tttttatatt aaatttttaa ataagaattc aagattactc
     8401 ctcaaaaact caacatatca acatacaaaa ataaaaattt tttaattttt tatgataaat
     8461 agttgctttt tttatgaaaa cggtttatac ttaaacagtc ttaaagtttt cttaaatgaa
     8521 aactaaaaca aaaaaggagg aatgacaata atgagtatcg gaatcattat tgcgagccac
     8581 ggcgaatttg ctgcgggtat tcatcagtca ggatctatga tctttggtga acaagaaaag
     8641 gttcaagttg tgacctttat gccaaatgaa ggtcctgatg atctatacgc taagtttaat
     8701 aacgctgttg ctgcatttga cgcagaagat gaggttctag ttttggctga cctttggagt
     8761 ggttctccat ttaaccaagc tagtcgcgtg atgggagaaa atcctgagcg taagtttgcc
     8821 atcatcacag gacttaactt accgatgttg attcaagcct acacagagcg cctcatggac
     8881 gctgctgcag gtgtagaaaa agtcgctgct aatatcatta aagaagccaa ggatggcatc
     8941 aaagctcttc cagaagagct aaatccagtt gaagaagttg caagcgctgc agctgctcca
     9001 gttgcccaag ctgctatccc agaaggaact gttatcggag acggtaaatt gaaaatcaat
     9061 cttgcccgtc ttgacacacg tctacttcac ggtcaggttg caactgcttg gactccagat
     9121 tcaaaagcaa atcgtatcat cgttgcttca gataacgtgg ctaaagacga ccttcgtaaa
     9181 gaattgatta aacaagcagc tccaggtaat gtcaaggcta acgtggttcc aattcaaaaa
     9241 ctgattgaga tttcaaaaga cccacgtttt ggagaaacac atgcccttat cttgtttgaa
     9301 acacctcaag atgcccttcg tgccatcgaa ggcggcgtgc caatcaagac tcttaacgtt
     9361 ggttctatgg ctcactcaac aggtaaaaca ttggtcaata ccgttttgtc tatggacaaa
     9421 gaagatgttg cgacatttga aaaaatgcgt gacttgggtg ttgaatttga tgtccgtaaa
     9481 gtaccaaatg attctaaaaa agatttgttt gacttgatta acaaagccaa tgtcaaataa
     9541 gccattattt atgaaaggat tttaaacatg tctattattt ctatggtttt agtagtcgtt
     9601 gtagccttct ttgcaggtct tgaaggcatc ctcgaccagt tccaatttca ccaaccactt
     9661 gtagcctgta cccttattgg gcttgtaaca ggtcacttgg aagcagggat tatcctcggt
     9721 ggatcgcttc aaatgattgc ccttggttgg tcaaatatcg gtgctgctat cgctcctgat
     9781 gctgcacttg cttctgtcgc tgctgccatt atcatggttc ttggtggtga ctttaccaag
     9841 actggtatcg gtgttgccca agcggttgct atccctcttg ccgtagctgg acttttcttg
     9901 acaatgattg ttcgtacaat ttcagttggt ttggttcata ctgcagatgc tgccgctaaa
     9961 aaaggtgact tcggcgctgt ggagcgtgcg catttcattg cgctactctt ccaaggactt
    10021 cgtatcgcgc ttcctgcagc tcttctcctt atggtaccaa ctgaaactgt acaaagtatc
    10081 cttagtgcca tgccagactg gctcaaagat ggtatggcta tcggtggtgg tatggtcgtt
    10141 gccgttggtt acgccatggt tatcaacatg atggcaactc gtgaagtatg gccattcttc
    10201 gctcttggtt tcgttctcgc tgctgtgtca gatattactc taatcggatt cggtgctatc
    10261 ggtgttgcta tcgctcttat ctaccttcac ctttctaaaa ctggtggaaa tggtggcgga
    10321 ggagccgcaa cttctaacga cccaatcggc gatatcctag aagactacta agataagaaa
    10381 ggactgaaaa catcatgact gaaaaacttc aattaactaa atcagatcgt aaaaaagttt
    10441 ggtggcgttc aaccttctta caagggtctt ggaactttga acggatgcaa aacttgggct
    10501 gggcttatac actcattcca gctatcaaaa aactctatac taaaaaagaa gatcaaatcg
    10561 ctgctcttga gcgtcacctt gagttcttca acactcatcc atacgtagct gctccagtca
    10621 tgggggttac tcttgcgctt gaagaagaac gtgctaacgg tgtggaaatc gatgacgctg
    10681 ctatccaagg ggtcaaaatc ggtatgatgg gacctcttgc tggtatcggt gacccagtat
    10741 tctggtttac agtacgccca atccttggat ctctcggtgc ttcacttgcc cttactggca
    10801 atatcttggg tccactcctc ttctttgttg catggaactt gattcgtatg tcattcttgt
    10861 ggtatgttca agagattgga tacaaggctg gatcagaaat cactaaagat atgtctggtg
    10921 gtatccttca agatatcact aaaggagctt ctatccttgg gatgttcatt cttgctgtcc
    10981 ttgttcaacg ctgggtaaat attaaatttg ctttcgatgt ttctaaagtt caactagatg
    11041 aaaaggctta tatccattgg gataaattgc cagaagggtc taaaggtatc caagaagcat
    11101 tcgcacaagt aggacaagga ttgtctcaaa ctcctgaaaa agttactact ttccaacaaa
    11161 acttggatat gttgattcct ggattatcag gactactcct tactttactt tgcatgtact
    11221 tacttaagaa aaaagtatct ccaatcacta ttatccttgc cctcttcgca gtgggtattg
    11281 tggcacatgt tcttcacatc atgtaatcaa gcaactaaaa aggaaccagg ttctaaaatc
    11341 tgattccttt tttctatgct tttattcagc caaggctccc attggatccc atggtgcaag
    11401 tacaattggt tctgctccat aggcagcttg ttcttctgct gtcagcaatt ccttacgaac
    11461 aacgatttgg tatgtgtatt cgtccatcca agcgtctgag gcaacaaagt aaccatctgt
    11521 accgaccttg tctccccatg agttttcaac cttccacttg gttgatttac cattttcgtc
    11581 caagtcaaca cctgtcaaga ccatggcgtg ggtcatcaag ctttcgctat agtccaaacg
    11641 tccagccttg tcttgagtaa gtttaatgtc catgcttgat tcaaagtcat aaacatctgt
    11701 cgcaaggatg ccagccttac ggttactgag ctggccgaca tcagaaccaa accaaacagt
    11761 ctcacctgct tgcatttggg caatcgccaa ttctttcaag cgctccattg gaacgttgat
    11821 gtaacgaact gcacggctac caaccacatt ccccaacatc tcaactgtgt aagattttcc
    11881 gtaaggttta tcagcagttg gagcattgat aacagaaacg tagtcttcta aaggaagatt
    11941 gacatatttc ttgtaaaact cttgtggtgt gattcctttt tcacttttgt agttgttatc
    12001 tttatcgcga taagcaaagt caaacttgcg tggtggaagt cctaatgaca tagcaagaaa
    12061 gttaaagatt tcttgcaaga ggtcttcttt cttagcttga acagtcgctt gatctgcacc
    12121 agaaacaagc aagtcacgca agatttgagc atcttgacga agcaatttat taaggatcgc
    12181 atttagctca cgactgctgc tagatgaaac agactcagga taaactgact taggcacgac
    12241 accgtatttt tcaaagaggg aaacgaccat atcccattga ccaccatctt gttgaggtgt
    12301 ttgaagtaag aagctaacct tgcggctagt caattcttgg tctgaagtcg caatgacttg
    12361 ctccaagaac cagtttgatt tctcatactt atcccagaag aaagtgtggg cttgtgacaa
    12421 ctcaaagttc tccaatttgt attgcgagat gagtttgtgg cggaaggtgt tgagagccgc
    12481 aaacatccag caacgaccag acgctttctg gttagtgacc ttgtccttgg ttaaatccaa
    12541 tgagaaaaca ggtgtgttgt ctacatggct ttggcgacgt tccagagctg caaaaattcc
    12601 gttgtggcta gcagcatttt caatcgcttg gtattttaca tttgcttcat agttggcaaa
    12661 tagtttatca gtaaatgatt cttgaatcgc gttcatagat tcctcctttt attctacagt
    12721 ctattataac tcttttcaca aaggaagcaa ctaaaaaaca taaaaggtaa ggacattctc
    12781 cctcaccttt ttcgaatata aatcaaatta agcaatacta gcaaggagaa tttctaattc
    12841 ttccttggtc aagcgacgcc attcccctcg ttccaggttc tcatctaata ctaaagttcc
    12901 catagtcaat cgttgcaagt ccaccacttc cttgccacag tagcccacca tacgcttgat
    12961 ctgatgaaac ttcccttctg caatggtcac acggatttgg ctttgattct tttctgtatc
    13021 tatggataca agctccagta tagcgggttg acaggtaaag tctttgagag gaataccctc
    13081 agcaaatatc tccacatctt cttgggtcat gattcccttg acttgtgcca gataagtctt
    13141 gtccacatga cgcttgggcg aaagaagaac atgagccagc tgaccatcat tggtcaagag
    13201 caaaagacca tgcgtgtcaa tatccaagcg tcctactggg aaaatttcct tactccgcgc
    13261 caagtcatcc aacaagtcca gaacggttct gtgcttggga tcctcagtcg ctgatataac
    13321 tcctttgggc ttgttcatca tgtagtagac aaactcttca tactccaaca cttgcccatc
    13381 aaagcgaatc tcatctattt tttcatcaat ctgcaattta gctgattttt cttttttacc
    13441 atttacagtc acgcgcccag ccttgagcaa gtttttgacc tcagtccgac ttcccaccgc
    13501 acaggcaact aaaaatttat ctaatctcat agaactatta tatcatatca aaaggaggct
    13561 ggtacaatga ccaacctcct tttcgtttca tactcttcaa aaatctcttc aaaccgcgtc
    13621 aacgtcgcct tgccgtatat atgttactga cttcgtcagt tctatctgca acctcaaagc
    13681 agtgctttga gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtatc
    13741 agatttaaga aattaacttc ctcgtctcca aaaaatagct aagacaatca tggcacctaa
    13801 aacagctggg ataatagctg ttcctgataa aactggcccc caagttccaa agagcaagtg
    13861 acctagaaag gctccgatcc aaccgagaaa catttttcca aaacatccca ttcgctctcc
    13921 acgattggtc atagcacctg ctaaaaatcc cactaggaga ccaacgaaca tacttcctaa
    13981 catattatct ccttaatttg cccaattccc attacggaaa agaggtactc gcgttccatc
    14041 ctcacgaata ccatcgatat ccatttggtt agaaccaatc ataaagtcta cgtgaacatc
    14101 tgaacggtta agccctgcag cttcaagctc ctcttcgctc atctccgctc catcaacaac
    14161 gctagtcgca taggctgcac cgatagccaa gtggtttgac gcattttcat cgaaaagggt
    14221 gttaaagaag gtaatgcctg actgagaaat tggacttgga tctggtacca aggcacattc
    14281 acccaaggca cgcgcacccg cattttcaaa gacaaggtct ttcataacct gatcaccctt
    14341 ctcagcagtg atatctacga tttgtccatc cttaaaggtc accttaatgc cttcaatgat
    14401 atttccgttg tagctaagcg gttttgtaga agtgacataa ccatctgcac gacggaagtc
    14461 aggcgctgtg aagacctctt ctgtcggcat atttggcaag aattcttcgc cctgtgcatt
    14521 gacagcacca gctgattccc aaacgtggtt ctttggcaaa ccaagtgtta aatctgttcc
    14581 tggcgctgtg tagtgaaggg ctgaaaattg ctccttatta agcatatcgg ccttgctctt
    14641 gagaatggct gcatgttcct cccaagcctt aacaggatct gcttcgtaga cacggcaagt
    14701 tttgaaaatt tggtcccaaa ggaaatcaac tgcttcttcg tcgctcgcag catttgggaa
    14761 gactttctta gcccactcaa gtcctgctgc agctgctaca gtccagctaa ccttgttaga
    14821 ttgagttgcg attcgcattg gcttcatggc aagtcccata gctttagcag aagctgaaag
    14881 cttgtcagcg tccactccgt tcaaggcacc tggatcagat gaacgaactc caagacggct
    14941 agccttgttc tccaagagat agttcatctc agcaatcttg tattctggca cattgtccaa
    15001 acgctccatc ggggcatgga ggaatttctc acggttaatc acatcatctg tccactgaac
    15061 gatgacctca tgcgcaccca aggcataagc ttctttcacg attagatgtg ccaattcacg
    15121 ttgctccaca tcaatagaga gagccaaagt gtgaccaggt tgcacgttaa ttccgttcgc
    15181 aaccaacaat ttcgcatatt tttctagatt ttctttaaaa tttggtaaaa ccatcctgtt
    15241 ttctcttttc tatttttatt tttctttcaa agcagaaaag attcctgcta aagcaatagc
    15301 acctgacaag agtgctgtcg atagaagaat tgtacgatca gcaagttcta attgatattc
    15361 aaataccttc ttagccggct tatcttccgc aaatattctt agtttcatga gaaccccctt
    15421 aaaatagatt aaaataaatc actgtgactg cctgtcctca gcaaatttaa aatcaattcc
    15481 gacttatcta ctttataaac caaaagccaa tctggctggg tatggcattc acgaactcct
    15541 tgaaaatgct tggatgccgt caatgaatga tcacgatatc tggcaggatg ttctttttct
    15601 tgaaccagaa aattcaaaac ttcttctaat aattctgcct tcaaaccacg cttcatagcc
    15661 aacttaaaat cttttttaaa ctgtttatga taacgaatct taagcacgta agtcctccat
    15721 caaatctgag actgattcaa aagactggct catattacga ttttggtcta aatccgttaa
    15781 cacttggagc aacttccgat tttcgtctag tctaacatca aaaggtaatc cctgatattg
    15841 aattgcctga cgaaggaaaa tattaatagc tgttgtcata tccattccca gattactaaa
    15901 cacctgttgg gcctgctcct taacctcact atccagacgg atgctcatac tcatctttga
    15961 catactctca ccctctttcc atagactatt ttaacaaaaa agaaagctaa tgtaaatcta
    16021 ttggatatac gttagcctct tctaatagat tattaagcaa ttttttaaaa caactcatca
    16081 aacaaactca actggttatc ctctggcata tttccaagaa tacccatctc atccatcttt
    16141 tcaaccaagg ttgatgagag tccaccacgc ttgcgtagtt ctgttttaga gaggaattct
    16201 ccctcttcac gcgcccgcac cagttgcttg gcaacgttct ctcccagacc atccattgct
    16261 acaaatggtg ggataagggt atccccgtcg atgaggaact ctgtcgcctg actacggtag
    16321 agatctaatt tgccaaactt gaaacctcgt tcccacatct cattgacaat ctcaagagtt
    16381 gtatagagat cgatttccac attagaggct tcattgttct tccgtttttc agagatttct
    16441 tccattctgc gcttgatggc ctccaagccc gcacccatgg tcttgatatc aaaagcctta
    16501 gcacgaatgg agaagtaagc acagtagtaa taaataggat ggtgaacctt gaagtaagct
    16561 acacgcaagg ccatcataac gtaggctgcc gcatgggcct tagggaacat gtacttaatt
    16621 ttcccacagg attcgatata ccactctggc accttattag ccttcatggc ttcgatatag
    16681 ccatttctct cctcttctga aatctttagc cacaaaccct tacgtacccg ttccataatg
    16741 gtaaaggcca tcttaggttc cagacccgca tgcatgaggt aaaccatgat gtcgtcccga
    16801 caaccgataa cagtcgatag gtccgctatt ccttgcttaa tcagatcctg agcattcccc
    16861 aaccaaacgt cagtaccgtg ggacagacca gacagctgaa gcaattccgc aaaggttgtc
    16921 ggatgggttt cgtctaccat tccacgtacg aaatttgttc caaactctgg aatccccaac
    16981 atacccgtag gcgttccaat ttgttcaggt gttaccccta gcacatcagt cccagaaaag
    17041 agtgccatca cgccttcgtc atccatagga attttattag ggtcaatacc agacaaatcc
    17101 tgaagttttc gaatcatggt cggatcatca tgtcccagta catcgagttt gaggacgttc
    17161 tcatcgatat cgtggaagtt aaagtgagtg gtctgccatt cagccgtgac atcatctgct
    17221 ggatactgga caggcgtaaa atcgtagaca tccatgtagt tcggaataac aacgattccc
    17281 cccgggtgtt ggcctgttgt ccgcttgaca cccgccgctc cttgagcgag gcgttctact
    17341 tctgcatcac gataaaactt gccataatct cgctcgtaac ccttgacaaa tccataggca
    17401 gtcttggcag ctaccgtacc aaccgttccc gcacggaagg catattcttc accaaagata
    17461 tcacgcacat ccaagtgggc gctaggctga tcttctcccg agaagttcaa gtcaatatca
    17521 ggaaccttat ccccatcaaa accaaggaag gtctcaaacg gaatatcctg tccgttttta
    17581 ctgagtttgt gaccacagtt tggacagtcc ttatggggca tatcaaatcc tgaaccgtac
    17641 gaaccatctg tgataaactc actgtactga cactgaccac agacatagtg aggagagaga
    17701 ggattgacct ccgtaatccc aatcatggtc gcaacgaaac tagatccgac agacccacga
    17761 gaaccaacca aataaccccg ttcattagaa cgttgcacca gcatctgcga tgccagataa
    17821 atcacagcaa atccattccc cagtatggat gttaattctt tttcaatccg caaatcaaca
    17881 atatctggca gcggatttcc ataaatctca aaagctttct tataggtcaa ctcagcaact
    17941 gtttcttcag ccttgttgat gaaaggcgta tacaagtcac ccttaacgac ttcaacgggt
    18001 tcaaatattt ctgccaaggc attagtgttt tcaataacca gtttacgagc cagttcctct
    18061 cccaaaaagg caaattcatc caacatctca ttagtcgttc gaaaatgagc ctttggaagt
    18121 ggcgctggtt gggcatgttc accatgaccg atagttcggt taatcatcgc accctgtccc
    18181 aaactacgga cgataatttc acgataaatc tcttcttccg gttcgatata gtgaacattt
    18241 cccgtagcca gaacaggctt gccaaggcga tctccaacct ctatcaaact cttgataatg
    18301 gtctggagtt cctccatatc cttgacctgc tctttggcaa tcaagggcgc atagatagcc
    18361 ggtggcatga cctcgataaa gtcataatac ttggccacct caaccgccgc atccacacct
    18421 tgagaaacga ccacgtcaaa aacttcaccc tctgaacagg ctgaacctaa aatcaagccc
    18481 tctcgatggg catctagaac cgttctcgga atccgtggca ctccttcaaa atacttggta
    18541 ttagacaagg aaaccagctt aaagatattt tttagaccta cctgattctt gacatagatg
    18601 gtcgcatgct tgatccgagc ttttttgtaa gaatctggac tgattagatc aatgttgagt
    18661 ctagctaaat cggtcacacc atgtttttct gctacctctt tgataaagat gaaaagcaga
    18721 cgaccagtcg cttccgcatc gtagttggcc atgtggtgat gttccaaggc cacaccaaaa
    18781 cgcttggtca aaggccccaa accatggcgt ttatactcag gatagaggtt tctagcaaac
    18841 tccagcgtat caataactgg ctgactaatc tttggaagac catgacgctc ataattagca
    18901 ttcataaagc caacgtcaaa ggcagcattg tgggcaacta ggaccgtatc cttgcaaaat
    18961 tcttggaatt cttgcaaaac ttgttctagt ggtttggcat ttttgacatg atcatctgta
    19021 attccagtta actctgtagt aaaagctgac aagggatgcc caggattgat aaattcatca
    19081 aattcagcaa taacattccc cttgtacatc ttagaggccg caacctgaat caagtcatta
    19141 tagatagctg aaagtcccgt cgtttccacg tcaaagacca cgtaggttgc ttctgataag
    19201 tccatctcca cttcgttata gacgataggg acacggtcct ccacgatatt ggcttctatc
    19261 ccatagatca gctggattcc cgctttctta gccgccttat agccatgtgg aaaggactgg
    19321 acattcccat ggtctgtgat agcaaccgcc ttgtgtcccc acttagcagc tgttgcaaca
    19381 atctcttcga cctctggcaa agcatccata gtcgacatgt tagtatgagc atgaaactca
    19441 acccgacgct caccttctgg catcaaatcc ttccgctcat agtgaacaac ttcctgcaga
    19501 tcctgtacgt tcatagtcaa atcgcgtgtg aagttattca tctccacatt ccctcgaact
    19561 cggagccaag aattcttctt gatgaggtca aacttctggg cctcttcctc gtttttaacc
    19621 cacttttgca tagaaaaact tgaagtatag tccgtcattt taaagttgat taaaacacga
    19681 cctgttctag tcactttttg ctccacatca aaaacaaccc cttcaaatac cagacgattt
    19741 tcctctgtcg tcacttcgat cataggagta atctccgcct tatccagctt gggtttagct
    19801 gcagcttttt tcgcttgaaa atcaaagact ggtttctctt ccgctggagg aggtgccatc
    19861 tgctccagtt gttccatagc acggagcgct tcctcattgg cagcttgaac aatctgctca
    19921 ttttcagcat gaaaggcctc ttcctgctct tgggtcagga catcattctt ctcgacttga
    19981 cagttaaaag ttggaaaacc aaacttttca agttgtttgg ctaaattagg aagatgattc
    20041 ttcttaaaat gttccttatc aatcgcttca gatccttcaa taaatagctg attaccctca
    20101 gcacgaactt gcaaattttg ataaagggac ttaaaacctt gactagcaca tggaccttca
    20161 gagaaagcct ccctatagta ggactgcaag agctgatttg aaaattcttg agaccgagcc
    20221 ttagtttcaa aaacagcttt attgcctgtc ttagaaaatt cttcgctcaa acctttcttt
    20281 aattctaaaa agatttcaat cggtaaaata ttagaaaata cgaaatgaaa ctcccatacc
    20341 ttactaattt tatgaaccac aactcgctca atattggcct gtgctaaagc aggagcctgt
    20401 ctcatttcag caggcatccc caattgattc atcaaaattt caaaactatt tgacattcat
    20461 tttcctcaca ttattcttct actattttac catatttaga ggtatt
//
LOCUS       DBEROT010000039        20238 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.39, whole genome shotgun sequence.
ACCESSION   DBEROT010000039 DBEROT010000000
VERSION     DBEROT010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.39"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            69..311
                     /gene="relB"
                     /locus_tag="ACL8CG_001681"
     CDS             69..311
                     /gene="relB"
                     /locus_tag="ACL8CG_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGS1344238.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            313..567
                     /locus_tag="ACL8CG_001682"
     CDS             313..567
                     /locus_tag="ACL8CG_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGS1344239.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            614..1357
                     /locus_tag="ACL8CG_001683"
                     /pseudo
     CDS             614..1357
                     /locus_tag="ACL8CG_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(1646..2632)
                     /locus_tag="ACL8CG_001684"
     CDS             complement(1646..2632)
                     /locus_tag="ACL8CG_001684"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGS1344240.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2826..5294
                     /gene="gyrA"
                     /locus_tag="ACL8CG_001685"
     CDS             2826..5294
                     /gene="gyrA"
                     /locus_tag="ACL8CG_001685"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGS1344241.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5294..6037
                     /gene="srtA"
                     /locus_tag="ACL8CG_001686"
     CDS             5294..6037
                     /gene="srtA"
                     /locus_tag="ACL8CG_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGS1344242.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWNAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            6281..7078
                     /locus_tag="ACL8CG_001687"
     CDS             6281..7078
                     /locus_tag="ACL8CG_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGS1344243.1"
                     /translation="MISSEFISKIEFACNKKEGLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            7226..8486
                     /locus_tag="ACL8CG_001688"
                     /pseudo
     CDS             7226..8486
                     /locus_tag="ACL8CG_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            8582..9856
                     /locus_tag="ACL8CG_001689"
     CDS             8582..9856
                     /locus_tag="ACL8CG_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGS1344244.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKEHDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            9866..10744
                     /gene="truB"
                     /locus_tag="ACL8CG_001690"
     CDS             9866..10744
                     /gene="truB"
                     /locus_tag="ACL8CG_001690"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGS1344245.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            10985..11287
                     /locus_tag="ACL8CG_001691"
     CDS             10985..11287
                     /locus_tag="ACL8CG_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS1344246.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            11395..12033
                     /gene="udk"
                     /locus_tag="ACL8CG_001692"
     CDS             11395..12033
                     /gene="udk"
                     /locus_tag="ACL8CG_001692"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS1344247.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            12161..13501
                     /gene="xseA"
                     /locus_tag="ACL8CG_001693"
     CDS             12161..13501
                     /gene="xseA"
                     /locus_tag="ACL8CG_001693"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGS1344248.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLIIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            13479..13691
                     /locus_tag="ACL8CG_001694"
     CDS             13479..13691
                     /locus_tag="ACL8CG_001694"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGS1344249.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            13688..14563
                     /locus_tag="ACL8CG_001695"
     CDS             13688..14563
                     /locus_tag="ACL8CG_001695"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGS1344250.1"
                     /translation="MKKQEKLALVESVLEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIASLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIVFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            14556..15371
                     /locus_tag="ACL8CG_001696"
     CDS             14556..15371
                     /locus_tag="ACL8CG_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGS1344251.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            15364..15795
                     /locus_tag="ACL8CG_001697"
     CDS             15364..15795
                     /locus_tag="ACL8CG_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1344252.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            15802..17469
                     /gene="recN"
                     /locus_tag="ACL8CG_001698"
     CDS             15802..17469
                     /gene="recN"
                     /locus_tag="ACL8CG_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGS1344253.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSEIYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            17471..18199
                     /locus_tag="ACL8CG_001699"
     CDS             17471..18199
                     /locus_tag="ACL8CG_001699"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1344254.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            18278..20101
                     /gene="lepA"
                     /locus_tag="ACL8CG_001700"
     CDS             18278..20101
                     /gene="lepA"
                     /locus_tag="ACL8CG_001700"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGS1344255.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         6122 a         3580 c         4685 g         5851 t
ORIGIN      
        1 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
       61 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
      121 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
      181 ccctagaaga tgaatacgat gctcgtgtgg cagatttagc ctatcaagag tatttagaag
      241 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
      301 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
      361 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaagac
      421 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
      481 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
      541 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacagta tagaaagtaa
      601 ggagagtaaa aatttgaaga aaaaatggtt ttttgcagat tattatgaca caacaattat
      661 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgactgattt
      721 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
      781 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
      841 tttattgacc attctccctt taaatgctat ttttacagtg tttcgattag gacgtatctt
      901 ccgcttagca aggctgacaa aattactgaa actgactcgt ttacttagaa taattggact
      961 tacaggtaaa ctagaaagaa aaattagtag attcttacga acaaatggat tgatttatat
     1021 cttgtatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     1081 aaaatccttc tcagatagtc tttggtgggc tcttgtgaca gtaactactg ttggttatgg
     1141 tgatattgtt ccagtttccc tttttgggaa atggctagca gttttactga tgcttgtcgg
     1201 tattggaaca atagggatgc taacaagtgc tttgacgaac ttttttgtaa aggataatcc
     1261 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagctaaa gaatattaat
     1321 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     1381 aatatcataa aggtgagaca aaataaaact tgattcgagg agaaatcaag taagtcttga
     1441 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     1501 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     1561 tgatggggtg ctatttcaac ttcaacctac tataatacag aaaaaaacaa ctccctgatg
     1621 attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat tctggatttt
     1681 tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt
     1741 ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca acaacagctg
     1801 gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact gaaagtggaa
     1861 gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct actgcgatac
     1921 cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga acaccttcga
     1981 acaattcaat caattcagct tcttgaacat tttgagtgtc tttaaggaat tcttcaaggt
     2041 ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca
     2101 tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt gcttgacgga
     2161 aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg aaaccagaga
     2221 atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg aagatacctt
     2281 tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg tttttaccta
     2341 caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatc acaacaaggt
     2401 cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa gtgaaggcaa
     2461 gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt ggaatttcga
     2521 taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa gatgaaccta
     2581 cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc attgttttaa
     2641 acatctcctt aattttatta ggggattttc cctagacaac ttcattctat cacttttaaa
     2701 aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg gtttagaggc
     2761 tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa atgaggcatt
     2821 tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt
     2881 ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt cgagatggct
     2941 taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg accccagaca
     3001 aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat cacccacacg
     3061 gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc taccgttaca
     3121 tgcttgtaga tggtcatggg aattttggtt ccatggatgg agatagtgct gccgctcaac
     3181 gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat atcaacaaaa
     3241 atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg gtcttgccag
     3301 cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg atggcaacca
     3361 atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc atggataatc
     3421 ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt ccaactggtg
     3481 ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa ggttcgattg
     3541 tcctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgc atcgttgtaa
     3601 cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt cgcttggttc
     3661 aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc
     3721 gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat aacctcttca
     3781 aaatgaccca aatgcaaacc aattttggtt tcaatatgct cgctatccaa aatggtatac
     3841 cgaaaatttt gtctcttcgt cagattttgg atgcttatat cgagcaccaa aaagaagtgg
     3901 ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat atcttagaag
     3961 gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt gctagtgaaa
     4021 cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc
     4081 aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat
     4141 ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt gctaagcctg
     4201 aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa ttttctgata
     4261 aacgccgtac agagttgatg gttggacaga tcttgagtct cgaggatgag gacttgattg
     4321 aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt ttggatcagg
     4381 acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg
     4441 atgactttgt tcgtgagtta gtgtcaacta gcacacatga tcatctgctc ttcttcacaa
     4501 acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt cggactgcca
     4561 aagggctacc agtagtcaat ctcttgaaat tggatgaaga cgaaagtatt cagacggtta
     4621 tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc cgtcacggta
     4681 ttgtgaagag aactagtgtt aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc
     4741 tgaatttaaa ggatgaagat gagttaatca atgtcttgtt ggcagaagga gatatggata
     4801 ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta
     4861 tgagccgtat cgccactggt gtgaaaggtg ttaaccttcg tgaaggagac acagttgttg
     4921 gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa ggatatggta
     4981 agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga atgcagacag
     5041 ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa ggggatgagg
     5101 atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc aatatttcac
     5161 aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat gctcagatag
     5221 tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa aacgaaacag
     5281 aaggtgaagc ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa aaaatctgct
     5341 gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt ttaatactca
     5401 aattcgaaat attttcatag tctggaatac caataagtat caagttagcc aggtatcaaa
     5461 agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt ctgtcaaagc
     5521 tatctcttcg gaagctgttc taacttctca atggaatgct caaaaattac cagttattgg
     5581 gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac ttgataatgt
     5641 taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag aaggaaatta
     5701 tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt tattttctcc
     5761 tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata aagtttatac
     5821 ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag ttgatgatag
     5881 agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta cagaacgtat
     5941 tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatctg atgaaatcct
     6001 aacagctttc aatcaaccat ataaacaatt ttattaatac aaatcagtga aatcatggat
     6061 ttcactgatt ttttaagatt ttcataaaaa tatagtaaaa tgaaataaga ataggacgaa
     6121 tcgttcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
     6181 agtttcaatc tactataaac ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt
     6241 tgtgatataa ttatcaagaa aaaagattta ggagtttatt atgatttctt cagaatttat
     6301 ctcaaagatt gaatttgctt gcaataagaa agaaggtctt tatagtcaaa gcaaatttaa
     6361 gtatgcgatt cgttcgatgt tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc
     6421 agttggggct gacttgatta ataaaattgc accaggtagt ggacgcttcc tctttccatt
     6481 cgtttttgct tggggcttgg cctacattgt ttttttgaat gccgagttgg tcacttcaaa
     6541 catgatgttc ttgactgctg gtagtttctt aaaaaaaatc tcttggagaa aaacagctga
     6601 gattttacta tactgtacct tgttcaacct tatcggagcc ttgatagcag ggtggggctt
     6661 tgctcattcg gcagcctatg cgaatctgac acacgatagt ttcatctcag gtgttgttga
     6721 gatgaagtta ggccgctcaa atgaattggt cttgcttgag gcgattttgg caaatatttt
     6781 cgtaaatatt gcgattctgt catttatttt ggtcaaagat ggtggtgcca aactttggct
     6841 tgtgttgtca gctatttaca tgtttgtatt cttaacaaac gagcacattg cggcgaactt
     6901 tgcttctttc gcgattgtga aattcagtgt tgctgcggat tcaattgcca acttcggtgt
     6961 tggaaatatg cttcgccact ggggtgtgac tttcatcgga aactttatcg gaggaggcct
     7021 cttgatgggt cttccatatg ccttcctcaa taaaaacgaa gatacttatg tagattaaga
     7081 aaatgagcac gattgagtcg tgcttttttc attttcaaaa taaggtaaca gctatttctt
     7141 atatcaaaat atagaaaact gatatttgta aactataact caaggtgcta caatatcctt
     7201 aataaaataa tatggaggtc accttatgac ttgtgatttt aaatttgaaa ctctacaact
     7261 acatgctggt caagttgtgg ctccagctac taagtctcgt gcagtgccga tttaatcaaa
     7321 caacattttt tgtttttgat gacacgtagg aaggtgccga tatgtttgcc ttgaggaaac
     7381 cagggaacat ttatactcgt atcaccaatc ctacaacagc tgcccttgaa ggtggtgttg
     7441 aagcgctagc aacagcatca ggtatgactg cagtgactta tacgattttg gcgcttgccc
     7501 atgctggtga ccatgtagtg gctgcttcga ctatttacgg tggaaccttc aatcttttga
     7561 aagaacccct tcctcgttat ggtatcacaa caacctttgt cgatattgat aatttggagg
     7621 aagtagaagc agctatcaaa gacaatacca agcttgtctt gattgaaacc ttgggtaacc
     7681 ccttgattaa tattccagac ctggaaaaac tggcagagat tgctcataaa catcaaatcc
     7741 cacttgtgtc agacaatact tttgcaacac cttatttgat taacgtcttc tctcatggcg
     7801 ttgacattgc cattcactct gcgactaagt ttatcggtgg gcatggtaca actattggag
     7861 gaataattgt cgatagtggt cgttttgact ggacggcttc agggaaattc cctcaatttg
     7921 ttgacgaggg tccaagctgc cacaatttga gctatactcg tgatgtgggt gcagcagcct
     7981 ttattatagc tgttcgagtt caattgcttc gtgatacagg tgcagccttg tcaccattca
     8041 atgctttcct cttgctacaa agacttgaaa ccctttcact tcgtgtggaa cgccatgtac
     8101 aaaatgctga gacaattgtt gattttcttg tcaaccatcc taaggtagaa aagataaatt
     8161 atccaaaact tgcagatagt ccttatcatg ccttggctga gaaatacttg ccaaaaggtg
     8221 tcggttcaat ctttaccttc catgtcaaag gtggcgagga agaagcacgc aaggtcattg
     8281 ataatttgga aatcttctca gaccttgcta acgtggcaga tgccaagtct cttgttgttc
     8341 atccagcaac aaccactcat ggtcaattgt cagaaaaaga cctagaagca gcaggtgtca
     8401 caccaaatca aatccacttg tctatcggac ttgaaaatgt agatgatttg attgaagact
     8461 tgcgcttggc cttggaaaaa atttaaagaa aaagaagata aacagtggtt ttcgactcgc
     8521 tgtttttgat tttccttcat gcatgatata atggttacag aagtctagaa agaggaatgt
     8581 aatgaacgaa atcaaatgtc ccaactgtgg ggaagtcttt acagtaaatg aaagccagta
     8641 tgctgaactt ttgtcccaag tgagaacggc agagtttgat aaggaactac acgataggat
     8701 gaggcaggaa ctggccttgg ctgagcaaaa ggctatgaat gagcaacaga ctaaactggc
     8761 tcagaaggat caagaaattg cgcaattaca gagtcagatc caaaactttg atacagaaaa
     8821 agaattggcc aagaaagaag ttgaacagac aagccatcag gccttattgg ctaaggacaa
     8881 ggaagtacag gctttggaga accaattggc cactttgcgt ttggagcatg aaaatcaact
     8941 gcaaaagacc ctttctgacc tagaaaaaga acatgatcag gtcaaaaatc agctcctctt
     9001 gcaagaaaag gaaaatgagt tgtctttggc ttctgttaag caaaactatg aagcccagct
     9061 taaagcagct agtgaacaag tcgagtttta taagaatttt aaggctcaac aatctacaaa
     9121 agcgattggg gaaagcctag aacagtatgc agagagtgag tttaacaagg ttcgtagttt
     9181 cgcctttcca aatgcttact ttgagaagga taacaaggtc tcttcgcgtg ggtctaaagg
     9241 ggactttatc ttccgtgagt gtgatgaaaa tggagttgaa atcatttcta tcatgtttga
     9301 gatgaaaaac gaagcggacg gaacagagaa gaagcacaag aatgcagatt tttacaagga
     9361 attggacaag gaccgtcggg agaagaactg tgagtatgcc gttttggtga ccatgcttga
     9421 ggccgataat gactacttta acacagggat tgttgacgtc agccacgagt atgaaaaaat
     9481 gtatgttgtt cgtcctcaat tctttatcca gttgattggt ctcttacgta atgcggcgct
     9541 aaattcccta aaatacaagc aggagttggc cttggttcgc gagcaaaata ttgacattac
     9601 gcattttgag gaagatttgg atgcctttaa gctagctttt gctaagaact ataattcagc
     9661 ttcgactaac tttggaaaag ctattgatga aatcgacaag gccatcaaac gcatggaaga
     9721 ggttaagaaa ttcctgacca catctgaaaa ccaactccgt ctagctaaca acaaattgga
     9781 agatgtctct gttaaaaaat tgacccggaa aaatccaaca atgaaagcga agttcgaagc
     9841 actgaagggg gagtagaaag caaaaatgaa cggtattatc aacttaaaaa aagaagcagg
     9901 aatgacctcg catgatgcgg tttttaaact gcgtaagatt ttgggaacca agaaaattgg
     9961 tcatggtgga accttggatc cggatgtggt gggtgttttg ccgattgcgg ttggcaaggc
    10021 gacacgcatg gtcgagttta tgcaggacga gggtaagatc tatgaggggg aaattactct
    10081 gggttattcc acgacgactg aggatgctag tggggaagtg atcgcagaaa cccctgtttt
    10141 gtctcccttg gatgaaaagc ttgttgatga agcgattgct agcttgactg ggcctattac
    10201 ccagattccc cctatgtatt cggcagttaa ggttaatggt cgcaagctct atgagtatgc
    10261 gcgtgctggt caggaagtgg agcgtccaga acgtcaggtg accatttatc aatttgagcg
    10321 aacaagtccg atttcttatg atggccaact tgcccgattc acttttcgtg taaaatgcag
    10381 taaagggact tacatccgta ctttgtcagt tgatttgggt gaaaagcttg gttatgcggc
    10441 tcatatgtcc catttgactc gtactagtgc tgctggctta caattagaag acgctcttgc
    10501 cttggaggaa attgctgaaa aagtagaggc tgggcaatta gattttctcc atcctttaga
    10561 gattgggaca ggtgaccttg tcaaagtttt cctaactcca gaagaggcta cagaagttcg
    10621 ctttggtcgt tttattgagc tagaccaaac ggacaaagaa ctggctgcct ttgaagatga
    10681 taaattgtta gccattctag aaaaacgggg caatctctat aagccaagga aggtttttag
    10741 ctagatcgtt taggaataaa aatcgggtga tagataacaa ttgcttgata aaaccccata
    10801 ctaatagtag aatggttttg ggaattataa tattccaatt gttgcgagtt gtaggtactc
    10861 aaataatcta tatagaaatt tagaggtgtg aaatgaagca atttaaaatt ctttcagata
    10921 aatatttaga gtccattaca ggttctggtg ggaacttagg cccaggattt ggtgtgataa
    10981 ttccatgatg cgaaatgagt ttcgagaaag ggtggagcaa cttcttcaac aaaaagaaat
    11041 aaatgaaaat agtgagttga gtcacctgtt tcgtcttgct atacaaaatt tagacagaaa
    11101 tgaaaaatac caaacggtca tggccaattt gagtcaaggg ttgtcacttt acctcatgac
    11161 gcatcattac caggcaccta agtctgtcat tgattttggt ttatggattg ccaaagctcc
    11221 tagccaggaa agagggagac tggctttctt gcagatgctt gctcaaaccc tacagggctt
    11281 tcgttaaaac tgtcgaacat cagagggaag actctggtgt tttttgctga tgagactata
    11341 aattttgtaa aaaatgtgat agaatagacg acggataaaa taacggagga tagcatgcaa
    11401 aatagaccaa tcattattgg agtgacaggt ggttctggtg gtggtaaaac cagtgtttca
    11461 agagccattt tatcgcattt tcctgatgaa aagatttcca tgattgagca tgattcatac
    11521 tacaaggatc agtctcattt gacctttgaa gagcgtgtca aaaccaacta tgaccatcct
    11581 tttgcctttg atacagactt gatgatcgag cagattaagg aattgttggc agggcgtccg
    11641 gtggacatcc cgacctacga ctatacagag catacacgga gtagcaagac ctatcgtcag
    11701 gagcctcaag atgtctttat cgttgagggc attttggtct tggaggacaa gcgtctgcgc
    11761 gatttgatgg atatcaagat ttttgtggat acggatgacg atgtgcgtat tattcgtcgt
    11821 atcaagcgtg atatggagga acgtggccgt agccttgata gcgttattaa ccagtactta
    11881 ggtgtggtca aaccaatgta ccaccagttt atcgagtcaa ctaagcgtta tgctgatatc
    11941 gtcattcctg aaggggttag caataccgtg gctatcgacc tgttgacgac caagattgca
    12001 aagattttgg aagaagctcg aaacagcaaa taatcacatg tggaggcctt gcctcctttt
    12061 tctatttttc cctcataatg gtacataaat ggagattttt aggcatattt ttggtataat
    12121 aatacccata aaagagcaag taaatgaata gtaggtggag atggaaaagt atttatcggt
    12181 aacaactttg accaaatatc tgaaaatgaa attcgataaa gacccatact tggaacgggt
    12241 ctatttaact ggtcaagttt ccaactttcg taaacgacct actcaccaat atttctccct
    12301 aaaggatgac catgcagtta ttcaagcgac catctggtct gggatttatc agaaattagg
    12361 gtttgacctg gaagaaggaa tgaagatcaa tgtgattggg cgtgtacagg tctatgaacc
    12421 aagtggtagc tactccatca tcattgaaaa agctgagcct gatggggttg gggcgcttgc
    12481 gattcagttt gaacaactta agaaaaaatt gacagaagaa ggtctgtttc aagaacgctt
    12541 caagcaagct ctaccccaat tttctaagag aattggggtg gtaaccagcc gtagtggagc
    12601 cgttattcga gatattatca caaccgtcag caggcgattc ccaggtgttg acatccttct
    12661 ttatccgacc aaggttcaag gtgaaggggc tgcggaggaa attgctagaa atattgcgcg
    12721 tgctaatcaa cgggacgatt tggatttgat cattattggt cgtggaggtg gttctattga
    12781 ggatctctgg gcctttaacg aagaaattgt ggtacgagct atttttgaat ctcgtttgcc
    12841 agttatctct agtgtggggc atgagacgga tgtgaccttg gcagattttg tggcagatcg
    12901 acgcgctgca acgccaacag cggcggctga actggcaaca cctgtgacca agttggatgt
    12961 attagctcat ttgcaaaatc aggaaaaacg gatggcaacg gcagtccgaa atgttctatc
    13021 taagaaacaa gaggctttga aaaaatgcag tcagtctgtt atctttagac aacctgagcg
    13081 cttgtatgac ggttatttgc aacgcttgga ccaactgcaa ctgcgtttga aacaaagttt
    13141 gcgaactcgg atttctgata acaaacaatt agttcaagca agaactcatc aattagtaca
    13201 attatcacct gttaccaaaa tccaacgcta tcaagaccgt ttaggacagt tggacaagct
    13261 cttaggtagc caaatggcgt tagtttatga cgccaaggtt gctgaggcca agcgactttc
    13321 ggaagctttg ctcatgttgg atactagccg aatcgtggcg cgtggttatg ctattgtcaa
    13381 aaaagaagag tccattgtag attcggttga gagtttgaag aaaaaagacc aagtaacgct
    13441 tttgatgcga gatggtcaag tagaattaga ggttaaagat gtcaaaacaa aagaaatttg
    13501 aggaaaatct agcagaactg gaaaccattg tccaaagttt ggaaaatggt gaaattgctc
    13561 tggaagatgc gattactgcc tttcaaaagg gcatggtctt gtcaaaagag ctccaagcta
    13621 cgctggacaa ggctgaaaag accttggtaa aggtcatgca agaagacgga acagaaagtg
    13681 attttgaatg aaaaagcaag aaaaattagc tcttgtcgag tcggttttgg aagattttta
    13741 tggagaccag cagtttgcct ctagtttacg ggagtctgtt ctctattcta ttcatgctgg
    13801 tggcaagcgt attcggcctt ttctcttgtt agaagttctg gaagccttgc aggttgccat
    13861 caaacctgct cacgcgcagg tagctactgc cttggagatg attcatacag ggagcttgat
    13921 tcacgatgac cttcctgcta tggatgatga cgattatcga agagggcggt taaccaatca
    13981 caagaaattc ggtgaagcta tggccatttt ggctggagat gccttattct tagacccata
    14041 tgccttgatt gcgcaggcag atttgccaag tcagatcaag gtggacttga ttgccagctt
    14101 atcccttgct tcaggtagtc tgggtatggt ggcagggcaa gttttggata tggagggcga
    14161 acaccagcac ttgtctctgg aagaacttca gactattcat gccaataaga ctgggaagtt
    14221 actagcctat cccttccaag cggcagctat tatagctgaa ttgtcacctg aaatgcaggt
    14281 gaagctgaaa actgtgggtg aattgattgg acttgctttt caagtcagag atgatgtact
    14341 ggatgtgaca gctagttttg aggaaatcgg taagacacct caaaaggatc tgcaggcaga
    14401 aaaatcaacc tatcctgcct tgttgggctt ggaagagtcc attgtctttt gtaaccaaac
    14461 cctggatcaa gctaatgaaa aattggaaga aattgcccag caggttccct ttgaaacaga
    14521 atcgattgta agtgtagtag aaagtttgag aatcaatggc taaggaaaga gtggatgtac
    14581 tagcttataa acaggggttg tttgaaacga gagagcaggc caagcgaggt gtgatggctg
    14641 gcctagtcgt agcagtcctt aatggagaac ggtttgacaa gccaggagag aaaattccag
    14701 atgacaccga attaaaactc aagggggaga aactcaagta tgtcagccgt ggtggtttga
    14761 aactggaaaa ggccttgcag gtctttgatt tgtcggtgga tggcgcgact acgattgata
    14821 tcggggcctc tactggaggt tttaccgatg tcatgctaca gaatagtgcc aagttggtct
    14881 ttgcagtcga tgttggtacc aatcagttgg cttggaaatt acgccaagac ccacgagttg
    14941 tcagcatgga gcaattcaat tttcgctatg ctgaaaagac tgatttcgag caggagccga
    15001 gctttgccag tattgatgtg agtttcattt cccttagtct gattttgcca gccttgcacc
    15061 gtgtcttggc tgatcaaggt caggtggtag cacttgtcaa acctcagttt gaggcaggac
    15121 gtgagcagat tgggaaaaat ggaattattc gagatgctaa gattcatcag aatgtccttg
    15181 aatctgtaac agctatggca gtagaggcag gtttttcagt ccttggcttg gacttttctc
    15241 ccatccaagg tggacatgga aatattgaat ttttagcgta tttgaaaaaa gaaaagtcag
    15301 caagcaatca gattcttgct gagattaaag aagcagtaga gagggcgcat agtcaattta
    15361 aaaatgaata aaaaagaaag acttgaaaaa attagaagat tggtgacaga ttatcaaatc
    15421 ggcacgcaag aagaaattgt agaacatttg aaagaagcag gtatcactgc cactcaggcg
    15481 acggtatccc gagatatcaa agagttaggt attgtcaaaa ttcctttgag agacaacacc
    15541 tatgtctacg aattgccaaa atcaatcgta aaaagtctgc aactggctga agacaatatc
    15601 gaatcggctg aattgatgga taagatgatc aatctccaag ttattccagg aaatacggct
    15661 tttgtaaaag ctcagttaat cgagactttt gcagacaaga tttttagctg tttgactgat
    15721 gatagctcga ttttagtcat tgccagaagt ggaagtctag cagaggaaat ctttgaacaa
    15781 gtaaaaaatt ggtaggtcta tatgttactt gaaatttcga taaaaaactt tgccattatt
    15841 gaggctattt ccctcaattt tgaaaagggg atgactgtcc tgactggtga aacgggtgca
    15901 gggaagtcga ttatcattga tgccatgaat atgatgttgg gagctcgtgc gacgacagat
    15961 gttattcgtc atggtgcacc aaaggcagag attgaggggc ttttctcagt tgagaatagt
    16021 cgtcttttac aggaaatttt tgatgagcaa ggtttagaat taggtgatga aattatcatc
    16081 cgtcgggaaa tcttgcaaaa tggtcgtagt atcagccgtg taaatggtca gatggttaat
    16141 ctgtctgttt tgcgagctat tgggcaacat cttgtagata ttcatggtca gcatgaccat
    16201 gaggagttaa tgcgtcccca actgcatatc cagatgttgg atgaatttgg tgatgccgct
    16261 ttttgggact tgaaagaaac ctatcaaacg agttttgatg cctatcggaa aatgcgcaag
    16321 caggttctgg aagtcaagaa aaaccaacag gaacacaagg cacgtatcga aatgttggaa
    16381 tttcaaatgg cagagattga ggcagcaaac ttgcaggctg gagaagactt ggctctcaat
    16441 caagagcgag ataaactcct caaccacaaa aatattgcgg atacactgac caatgcctac
    16501 agtatgttgg acaatgaaga tttttcaagt ctggccaatg ttcgttcagc tatgaatgac
    16561 atggaaagtg tcgaagagta tgatcctgaa taccgtgaaa tttcaagctc tctgtctgag
    16621 atctactatg ttttagaaga cattagcaaa cgtttggaag ctatcattga ggaccttgat
    16681 tttgatggca atcgcctcat gcaggttgag aatcgtttgg acctccttca tactattact
    16741 cgtaagtatg gtgggactgt tgatgatgtt ttgctttatt ttgccaagat tacggaagaa
    16801 tacaatctct tgacaggcaa taatctttcg tctgaggaca tggaagcaga gcttaagaag
    16861 ttggaagtca atcttgtcaa tttggcaggt caacttgctt ctgctcgtca taatttggct
    16921 cagcaactcg aagctgagat taaacaagaa ctgcaagatc tttatatgga aaaagcccag
    16981 tttcaggttc gttttagtaa gggaaaattc agtcgtgagg gaaatgaaat ggttgagttt
    17041 tatatttcaa ccaaccctgg agaagacttt aaacccttgg ttaaggttgc ttctggaggg
    17101 gaattatctc gtctcatgtt agccattaag tctgcctttt cacgtaaaga aggcaagact
    17161 agcattgtct ttgatgaggt ggatacggga gtttcaggtc gtgttgctca agctattgct
    17221 cagaaaattc ataaaattgg tcagcatggt caggttttgg ctatctccca tttgccacaa
    17281 gtaattgcga ttgcagatta tcaattcttt attgagaaga ttagtaatga ccattcaacg
    17341 gtttcgactg ttcgtctctt gacggtcgaa gagcgagtgg aggaagttgc caagatgttg
    17401 gcaggtgatg atgtgacaga agcagccctg acgcaagcca gagaattgtt gagaaacagg
    17461 gagaaataag atgacagatt attatgtaat tggagatgtt cacggaaaag ctgggatgct
    17521 ggaagacctt cttaaaacct gggatggtca gacccagttg ctctttctag gtgatttgat
    17581 tgacagaggt gaggatagtc accgtgttct tgaaatggtc aaggacttgg tggacaatca
    17641 aggggctatc tgtttgtctg gaaaccacga gtatatgttt ttgacttggc tagatgaccc
    17701 agaagaaagt tatgaccatt atcgtcgcaa tggtggagat acaaccatta actctatcct
    17761 aggtcgtccc ttggatgcac cagttgatgg agtagaagat gccaagcggg ttgccgctga
    17821 agcggcagac ttggtcgaat tcattcgtca aatgccattt gtagtagaga cagacaagta
    17881 tatctttgtt cacgcaggta ttgatttgac cttggacgac tggcatgaaa caacagatta
    17941 taaaaaagta tggcttagaa aaccattcca cggagctgaa aatcatactg gaaaaaccat
    18001 tgtcttcggt catacaccgg tctatggttt gttacagcaa gaacgcggta catctgagct
    18061 ttggactaca gaagatggca agattggaat ggatggagga gctgtttatg gtggtgtcct
    18121 tcacgggatt gtctttacag accaaggaat gacagaacac cactttatcg aaaatgacgg
    18181 ctttgtcgct gaagattagt actcctagca gggtatggtc ttgtcaaaat atcaaaaaca
    18241 atttataata aatagatacc ctgaaaggaa gagaatcatg aacttagaag aattgaaaaa
    18301 acgacaggag aagatccgta acttctctat tatcgcccat attgaccacg gaaaatcaac
    18361 tctagcagac cgcattttgg aaaaaacaga gacggtttca agtcgtgaaa tgcaggccca
    18421 gcttttggat agcatggagc tagagcggga acgtggaatt actattaagt tgaatgccat
    18481 cgagttgaat tacactgcaa aagatgggga aacttatatt ttccacttga ttgacacacc
    18541 agggcacgtt gactttacct atgaagtttc acgttcgcta gctgcctgtg agggtgctat
    18601 tttggtggtc gatgcggctc aaggaattga ggctcaaact cttgccaacg tttatctggc
    18661 tttggataat gatttggaaa tcatgcctat cattaataaa attgacctgc cggctgcaga
    18721 tccggagcgc gtgcgtacag agattgaaga tgtgattggt ttggatgcca gtgaagcagt
    18781 tttggcttct gccaaggctg gtattgggat tgaagaaatc ctcgagcaaa ttgtagaaaa
    18841 agtaccagca ccaacgggtg atgtgacggc gccacttaag gccttgattt tcgactctgt
    18901 ttacgatgct taccgtgggg ttatcctcca agtacgtgtc atggacggag tggtcaaacc
    18961 tggtgataag attcagctca tgagcaatag taagaccttt gatgtggccg aagtcggtat
    19021 ttttacacca aaagcggttg gtcgtgattt ccttgcgact ggtgatgttg gttacattgc
    19081 ggcgtctatc aagacggttc aggatactcg tgtgggtgat accgttacct tggcaaccaa
    19141 tcctgcggca gaaccattac atggttataa gcagatgaat cctatggtct ttgcgggtct
    19201 ctacccaatc gaatcaaaca agtacaatga cctgcgtgaa gcgcttgaaa aattgcaact
    19261 gaatgatgct agtcttcagt ttgaaccaga aacatctcag gcacttggat ttggtttccg
    19321 ttgtggattt cttggacttc tccatatgga tgttatccag gaacgtttag agcgtgagtt
    19381 caatattgac ctcatcatga cagctccgtc tgttatttac aaagttaatt tgaccgacgg
    19441 tgagtctatg gatgtgtcta acccatctga gtttccagac ccaactaaga ttgcgaccat
    19501 tgaagagcct tatgtcaagg cgcaaatcat ggtaccacag gagttcgtcg gagcagtaat
    19561 ggagctagct cagcgtaagc gtggggactt tgtgactatg gactatattg atgataaccg
    19621 tgtcaatgtt atctatcaaa ttcctcttgc tgaaattgtc tttgacttct ttgataaact
    19681 taagtcttca acacgtggtt atgcaagctt tgactacgaa ttgtcagaat atcgcccatc
    19741 taagctggtg aaaatggata tccttctcaa tggagataag gtggatgctc tcagctttat
    19801 cgttcacaag gactttgcct acgaacgtgg gaaactcatc gttgataaac tcaagaaaat
    19861 catccctcgc caacaatttg aagttccaat ccaagcggct attggacaca agattgtcgc
    19921 tcgtactgat atcaaggccc ttcgtaagaa cgtacttgct aaatgttatg gtggtgacgt
    19981 ttctcgtaag cgtaaactcc ttgaaaaaca aaaagctggt aagaaacgca tgaaatccat
    20041 cggatcagtt gaagttccgc aagaagcctt cctcagcgtc ttgagtatgg atgaagaata
    20101 agttatcaga aatgcctttc cttgttcaca ggaaatttat ataagaatca atagtaaagc
    20161 aggcttagat ggtctgcttt tttagttttt atactcttcg aaaatctctt caaaccacgt
    20221 catcgtcgcc ttaccgta
//
LOCUS       DBEROT010000040        18723 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.40, whole genome shotgun sequence.
ACCESSION   DBEROT010000040 DBEROT010000000
VERSION     DBEROT010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18723
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.40"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..393
                     /locus_tag="ACL8CG_001701"
     CDS             <1..393
                     /locus_tag="ACL8CG_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGS1344256.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKENK"
     gene            812..1186
                     /gene="dhaM"
                     /locus_tag="ACL8CG_001702"
     CDS             812..1186
                     /gene="dhaM"
                     /locus_tag="ACL8CG_001702"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGS1344257.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNAAA
                     LLQAGAELSVIQTQLAELEINK"
     gene            1645..2358
                     /locus_tag="ACL8CG_001703"
     CDS             1645..2358
                     /locus_tag="ACL8CG_001703"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGS1344258.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2372..3019
                     /locus_tag="ACL8CG_001704"
     CDS             2372..3019
                     /locus_tag="ACL8CG_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344259.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCIGDFPHDFFDTYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3155..3808
                     /locus_tag="ACL8CG_001705"
     CDS             3155..3808
                     /locus_tag="ACL8CG_001705"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGS1344260.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3818..4282
                     /locus_tag="ACL8CG_001706"
     CDS             3818..4282
                     /locus_tag="ACL8CG_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGS1344261.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECATREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4295..5563
                     /locus_tag="ACL8CG_001707"
     CDS             4295..5563
                     /locus_tag="ACL8CG_001707"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGS1344262.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5577..5837
                     /locus_tag="ACL8CG_001708"
     CDS             5577..5837
                     /locus_tag="ACL8CG_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344263.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5848..7209
                     /gene="pdrM"
                     /locus_tag="ACL8CG_001709"
     CDS             5848..7209
                     /gene="pdrM"
                     /locus_tag="ACL8CG_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGS1344264.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7363..8331
                     /locus_tag="ACL8CG_001710"
     CDS             7363..8331
                     /locus_tag="ACL8CG_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGS1344265.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYHWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8347..9339
                     /locus_tag="ACL8CG_001711"
     CDS             8347..9339
                     /locus_tag="ACL8CG_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex E1 component
                     subunit beta"
                     /protein_id="HGS1344266.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            9557..10600
                     /locus_tag="ACL8CG_001712"
     CDS             9557..10600
                     /locus_tag="ACL8CG_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGS1344267.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10646..12349
                     /gene="lpdA"
                     /locus_tag="ACL8CG_001713"
     CDS             10646..12349
                     /gene="lpdA"
                     /locus_tag="ACL8CG_001713"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGS1344268.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12413..13402
                     /locus_tag="ACL8CG_001714"
     CDS             12413..13402
                     /locus_tag="ACL8CG_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGS1344269.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13473..14543)
                     /gene="xerS"
                     /locus_tag="ACL8CG_001715"
     CDS             complement(13473..14543)
                     /gene="xerS"
                     /locus_tag="ACL8CG_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGS1344270.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSALENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(15118..16668)
                     /locus_tag="ACL8CG_001716"
     CDS             complement(15118..16668)
                     /locus_tag="ACL8CG_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGS1344271.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMSDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16684..17463)
                     /locus_tag="ACL8CG_001717"
     CDS             complement(16684..17463)
                     /locus_tag="ACL8CG_001717"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGS1344272.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17450..18301)
                     /gene="ylqF"
                     /locus_tag="ACL8CG_001718"
     CDS             complement(17450..18301)
                     /gene="ylqF"
                     /locus_tag="ACL8CG_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGS1344273.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            18383..18575
                     /locus_tag="ACL8CG_001719"
                     /pseudo
     CDS             18383..18575
                     /locus_tag="ACL8CG_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844782.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         5685 a         3492 c         3953 g         5593 t
ORIGIN      
        1 gaccatgttc aaagaaacaa aaatggtcaa gctgatacca atcaaacgga aaaaccaagc
       61 gaggagaaac ctcagacaga aaaacctgag gaagaaaccc ctcgagaaga gaaaccgcaa
      121 agcgagaaac cagagtctcc aaaaccaaca gaggaaccag aagaagaatc accagaggaa
      181 tcagaagaac ctcaggtcga gactgaaaag gttgaagaaa aactgagaga ggctgaagat
      241 ttacttggaa aaatccagga tccaattatc aagtccaatg ccaaagagac tctcacagga
      301 ttaaaaaata atttactatt tggcacccag gacaacaata ctattatggc agaagctgaa
      361 aaactattgg ctttattaaa ggagaataag taaaggtagc agcattttct aactcctaaa
      421 aacaggatag gagaacggga aaacgaaaaa tgagagcaga atgtgagttc tagttctcat
      481 ttttttatga aaatgtgcaa aatatagtag attgaaatta gaatagtata cctctacttc
      541 taaaacattg ttagaaatcg atttgactgt cctgttctta tttcatttta ctatatctta
      601 acagatagtg taaataaagg taaactattt actggctaat taatcagtta aacactagtt
      661 aaggagtaat gataaaaaag aacaatacta ttattgatgg ccagtctgtt ggctcttgtc
      721 ttaggagcat gtggtttttt ggacatatcg atcctggatc attctcatca ggattactat
      781 ttactgctat tttagaaact ggggtggttt gatggaaagt attggtcttg ttatcgtttc
      841 acattccaaa cacattgcag aaggtgttgt tgaactgatt agtaaagtag ctaaagatgt
      901 tccgattact tatgtaggag gaaccgaggg cggaggaatt ggaacgagtt ttgatcaagt
      961 agatagggtt gtttccgaaa atccagcaga tactttactt gccttttttg acctaggttc
     1021 tgctaaaatg aacttaaaaa tggtgactga tttcagtgat aaaagtatca tcatcaacag
     1081 ggttccaatt gtagaaggtg cctataatgc agctgctctt cttcaggctg gtgcagaact
     1141 gtcagttatt caaacacagt tagcggagct tgaaatcaat aaataaggaa ttttactata
     1201 actcttttta taggtaagct attgattatc tcaactataa aatgttaagt aaatgatttc
     1261 aaaatcagaa agggattgct ttatgcagtt cctttttatt ttaacaggag tgaaactata
     1321 gtgtttctaa attgtgaatc aatcaaaact gattgtgatg gggctattct agctttagaa
     1381 tccttcaaaa attaaaattt aaggcaatca attacttgga agagtatgaa agcatttagt
     1441 ttataggaat tctaggccta gaattacata tgtatttatg aagacggggt gttcgatagt
     1501 tagtattgtt ctattctgaa agatttgagc tgtcagttgt atagaaagtg ttcgaatttt
     1561 ttttaagtga ttaaattagt taattgtatg aggtgcttta tgatataatg ttcttaatga
     1621 attttcagaa aggaaaacct caaattgttc tacaaatttc tactcttcga cctcgaccac
     1681 actcttcttg attttgatgc tgctgaggat gtggctttga cccaacttct aaaagaagaa
     1741 ggagttgcgg atattcaggc ttataaagat tattacgttc ctatgaacaa ggctctctgg
     1801 aaagacttgg agctgaagaa aatcagtaaa caagagctgg ttaacacgcg cttttctcgt
     1861 ttattttctc attttggaca ggaaaaagac ggtagttttc ttgcccagcg ttaccaattt
     1921 tatctcgctc agcagggaca aacactatcg ggcgctcatg atctcttgga cagcctcatt
     1981 gagcgtgatt atgacttgta tgctgcgaca aatggcatta ctgccattca gacaggacgt
     2041 ttggctcaat ctggtctagt accttatttc aatcaagtct ttatctcaga acagttgcaa
     2101 actcaaaagc cggatgctct cttttatgaa aagattggcc agcaaattgc tggatttagt
     2161 aaagaaaaga cgctgatgat tggagattct ctaaccgccg acattcaagg tggcaataat
     2221 gcggggattg acactatctg gtataatcct catcacctcg aaaatcacac acaagcccag
     2281 ccgacttacg aagtctattc ttaccaagac ttgctggatt gtttagataa aaatattctt
     2341 gaaaagatca cattttaaag gagattagct aatgactaca aaaaaagcta atattactat
     2401 tgaagagtac attgaaatgt ctgaagttga ttttaatgaa gctgttaatt atgaatttac
     2461 atctgacact tgtcaattag caaatagtat ttatcaatct ctttttaagt tttttgataa
     2521 gaaaaatttc tctggcgatt taatttttac ttggaaatct ccatcattag tcaaagaagg
     2581 ggattatatt gggagaaggg attcacaagt agataatctt agagtaatag gaaatatatt
     2641 tccgaattat cttactaatc gaaaatatag cctcaatatg aatcgtaatg gctgtatagg
     2701 agattttcct catgactttt ttgatacata cctagatcat gtagcaaaat atgcctacga
     2761 acaaaaagtt aataatatta aagagtatta tcctttaaaa agagcgattt tacaccaaga
     2821 gaatgcattg tattttcgat tgttttctaa ttttgatgac tttttagaaa aaaattattt
     2881 aaagactata tggcaagttt ctaaagaaac tcctttttct gaaatggatt ttaatatgtt
     2941 taaaaatatt tcagaaaaga taatcttcga aagaggtagt aaaatgctta atgatttaaa
     3001 aagtaattat aaaaaatagc cagtctttat aaactgtatt cacgtattca aatcgtatat
     3061 agtcgattta ttaaatcttt agataaattg taaaaagtgg tttccatagc cactttttgc
     3121 tataatagag gcagtaaaaa tgaaggagtc agctatggaa cactcgtctt ggcatgcttt
     3181 gattaaggcg caattacctg agggttattt cgggaaaatc aatcagttta tggagcaggt
     3241 ctattctcag gggattattt atccacccaa ggaaaaggtt tttcaggctc tcttgacaac
     3301 actgcttgaa gaagttaagg tggtaattct agggcaagac ccctatcacg gaccaggtca
     3361 agcgcagggc ttgagttttt ctgtacctga ctctatccca gctccaccat ccttgcaaaa
     3421 tatcttgaaa gaattgtcag atgatatcgg agttaagaaa tctcatgatt tgacagcttg
     3481 ggctgagcaa ggagtcttgc ttcttaatgc ttgtttgact gttcctgctg gacaggccaa
     3541 tggtcatgct ggtcaaatct gggagccttt tactgatgct gtgattcagg tggtcaatca
     3601 tctagataga ccagtcgttt ttgtactctg gggagcttat gcacgtaaga agaaggcctt
     3661 agttaccaat cctcatcact tgattatcga atcagcccat ccaagtcctt tgtcggttta
     3721 tagaggattt tggggttcca agcccttttc caaggccaat gcattcttaa aagagacagg
     3781 acaagagcca atcgattggc ttagataagg agaaaatatg cctcagttag cgacgatttg
     3841 ctacattgat aatgggaaag aactgctcat gctccatcgt aataagaaac ccaatgatgt
     3901 ccatgaaggg aaatggattg gtgtgggtgg taagctagag agaggagaga cgccccagga
     3961 atgcgcgacg cgtgaaatcc ttgaagaaac agggctcaaa gccaagccag ttctaaaagg
     4021 tgtcatcact tttcctgaat ttacaccaga tttagactgg tacacctatg tttttaaggt
     4081 gacggagttt gagggcgact tgattgactg caatgagggg acgctagaat gggttcccta
     4141 tgatgaggtt ttgagcaagc cgacttggga aggtgaccac acctttgttg agtggctttt
     4201 agaggataaa cccttctttt cagccaagtt tgtttatgat ggggataaat tgttggatac
     4261 ccaagttgat ttctatgaat aaaggagaaa gcagatgcta ctaatcaaaa atggtcgtgt
     4321 aatggatccc aagtctggtt tggatcaagt ttgtgatgtc ttagttcaag atgggaaaat
     4381 tatcaaaatt gcgcctgaga tcacggaaga aggagcagaa acgattgatg ctactggtct
     4441 tgtggttgct cctggtttgg tcgatattca tgtgcatttc cgtgaacctg gtcaaacaca
     4501 taaagaagac attcatactg gtgccctagc agccgctgca ggtggtttta ctactgtcgt
     4561 catgatggct aataccagtc caaccatttc agacgtggag actttgcaag cagttctcca
     4621 gtcagctgcc aaagagaaga ttaatgtcaa gacagttgcg accattacta aaaactttaa
     4681 tggtaaaaac ttgactgact ttaaggcact cttagaagct ggtgcggttg gtttctctga
     4741 tgacggtatt ccgcttgaga gcagtaagat tgtcaaggaa gccatggagg aagccaaaaa
     4801 actcaatacc tttatcagcc ttcatgagga agatccaggt ttgaacggtg ttcttggctt
     4861 taatgaaaat attgctagag aacatttcca tatctgcggt gctactgggg tggctgagta
     4921 cgctatgatg gcgcgtgatg tcatgattgc ctatgcaact aaagcccatg ttcacatcca
     4981 gcatttgtct aaggaagaaa gtgttaaagt agtggagttt gctcaggggt taggtgcaga
     5041 agtcacagca gaagtagcgc cacagcattt ctctaagaca gaagcacttc ttttaacaca
     5101 aggtagcaat gctaagatga atccaccgct tcgtttggaa tcagaccgtc gtgccgttat
     5161 cgaaggtctc aaatcaggtg tcatcacagt tattgcgact gaccacgcgc ctcatcatgt
     5221 agatgaaaaa aatgttgagg atattaccaa agcgccatct ggtatgactg gcttagaaac
     5281 atccctgtct ctcagcttga cctatttagt agaagctggt gagttgagct tgatggaatt
     5341 acttgaaaaa atgacataca acccagccaa gctttacaac tttgaagcag gttacttggc
     5401 tgagaatggt ccagcagata tcactatttt tgatgccaag gctgaccgct ttgtggactc
     5461 ccattttgct tccaaagcag ctaattcacc attcatcggt gaaaccttaa aagggcaggt
     5521 taaatatacc atctgtaagg gacaaatcgt ctatcaagct tgataggagt tagaatatga
     5581 attattttcg aaaacgtagg gagagacaag cgaaatctaa tagtggaatt tactgtcccg
     5641 cagctaatcg ttccaaaatt caatatgaaa ctaaagaaaa agctgaccat gcggttcaat
     5701 atgataacgg aggtttagtt agaagctatt attgtcgtac atgtgcgtgt tggcatacta
     5761 cttcaaaatc taataaacct ccgctaagtt tgaaaaacta tggtctgaaa ctctttggtt
     5821 tagataaatc agaatagaaa gagaagtatg tataagacaa agtgtttacg agagaagtta
     5881 gtattatttt taaaaatttt cttcccaatc ctgatctacc aatttgccaa ttattctgcc
     5941 tcttttgttg atactgcaat gacaggtcaa tacaacacta tggacttggc tggtgtatct
     6001 atggcaacca gtatctggaa tcctttcttt acatttctaa cagggattgt gtcagccttg
     6061 gtgcctatca ttggtcacca tcttggtcga ggcaaaaagg aagaagttgc gtctgatttt
     6121 taccaattta tttatttggc cttgggccta tctgtggtct tgctggggat ggtacttttc
     6181 ttggcaccaa taatcttgaa tcatattggg ttagaagcag cagtagcggc agtagcggtt
     6241 cgctatcttt ggtttttatc tatcgggatt atccccttgt tgctctttag cgtcattcgt
     6301 tccttgctgg attcgctggg cttgaccaaa ctgtccatgt acctcatgct tttgttactc
     6361 cctctcaata gcggatttaa ctatctcttg atttacggtg cctttggtgt tccagaactg
     6421 ggaggggctg gtgctggttt aggaacatcc ttggcctact gggtcttgct tgggatttct
     6481 gttctggttt tatttaaaca ggagaagctc aaagccttac accttgagaa acgaattcca
     6541 cttaatatgg ataaaattaa ggaaggagtt cgtttaggtc tgcctattgg gggaactgtc
     6601 ttcgcggaag tggctatctt ttcagtggtt ggcttgatta tggctaagtt ttcgcccttg
     6661 attatagcta gtcaccagtc agctatgaac ttttcaagtc ttatgtacgc ctttcctatg
     6721 agtatctcat cggctatggc tattgtcgtt tcctatgaag tgggagccaa gcgatttgat
     6781 gatgcgaaaa cctatattgg tctaggaaga tggactgccc tcatttttgc ggccttcacc
     6841 ttaaccttcc tttacatttt taggggaaat gtggccagtc tttatggtaa cgacccaaaa
     6901 tttatcgatt tgacagtgcg ttttttaact tatagtcttt tcttccagtt agcagatacc
     6961 tttgcggcgc cgcttcaggg aattttgcgg gggtataagg atacagttat tcctttttac
     7021 cttggtttgc ttggttattg gggcgtagca atccctgtgg ctacgctatt tgattcccta
     7081 acagattttg gagcttattc ttactggatc ggcttgatta ttagtttgat tgtgagcggg
     7141 gcgctctacc gttggcgttt aactgtgatt atgaagagat ttgaatcttt agcaaaatcc
     7201 aaatgctaaa aagtttgtga aaaaatattc ttgacaagaa aatcccttgt tttcacgggg
     7261 ttttcttttt tattttgtga aatttctttt agaaaaactt tgacagtatt tgccaaaagc
     7321 ggtaaaatag taaggtaaga agaaagttag aaaggcaaga agatgtcaac tttagataaa
     7381 aatcttttgc tagaaatgtt ccgtaagatg gaagaaatcc gtcgcatgga cttaaaaatt
     7441 gcacaattag taaagaaagg gaaagtgcca ggaatgacgc acttttctgt tggtgaagag
     7501 gcagctaacg tgggggctat gttagctctc aatccagatg atctgattac ctcaaaccac
     7561 cgtggacacg ggcaagctat tgctaaaggg attgacctca acggaatgat ggctgaaatc
     7621 cttggtaaat acactggaac ctgtaaaggg aaaggtggat ctatgcatat cgctgacctt
     7681 gatgctggga accttggtgc caatggtatc gtaggtggtg gtatggggat cgctgtcggt
     7741 gcagccctca gtcagcaaat gcaaaatacc ggtaaaatcg ttgtctgctt ctttggagat
     7801 ggtgcgacca atgaaggtgt tttccacgaa gcagtgaaca tggcttctat ctggaacctg
     7861 ccagtcattt tctattgcat taacaacggt tacggtatct ctgcggatat caagaaaatg
     7921 accaatatag aacatatcca tcaacgtagc gccgcttatg gaattcctgg aatgttcatc
     7981 gaagacggta acaatgtcat cgatgtctat gaaggatttc agaaagctgt ggaccatgtt
     8041 cgcagtggca atggtccagt cttgattgaa agtgtaactt atcactggct cggtcactca
     8101 tcatctgacc ctggtaaata tcgtacgcgt gaagaagtgg aattgtggaa acaaaaagat
     8161 ccaatcgaaa acctccgcaa ttaccttatt gaaaataaca ttgcaagtgc cgaagaattg
     8221 gaagaaatcc aagcgcaagt aaaggaagca gtagaagctt ctgttaaatt tgcagaggaa
     8281 agcccattcc caccgcttga atcagccttt gaagatattt acgcagacta aggagaaaga
     8341 gataaaatgg aaacaaaaac aatgtccttc cgtgacacca ttatccttgc tatgtctgag
     8401 gaaatgcgtc gcgatgaaaa tgtgttcttg atgggagaag acgtcggtgt cttcggagga
     8461 gacttcggta cttctgttgg aatgcttgaa gaatttggtc cagaacgtgt ccgtgactgt
     8521 ccgatttctg aagctgccat ctctggagca gcagcaggag cagccatgac aggacttcgt
     8581 ccaatcgtcg atatgacctt catggacttc tctgttattg ccatggacaa tatcgtcaac
     8641 caagctgcta aaacacgtta catgtttggt ggtaaaggtc aggttccaat gactgttcgt
     8701 tgtgcagctg gtaacggagt tggctctgcc gcccagcact cacaatctct agagtcttgg
     8761 tttactcaca ttccaggact taaggttgtg gcacctggaa cacctgcgga catgaaaggc
     8821 ctgcttaagt cttctatccg tgataacaac ccagttatta tacttgagta caagtcagaa
     8881 tttaaccaaa aaggggaagt gccagttgat ccagactaca caattccact tggggttggt
     8941 gaaatcaaac gccaagggac ggatgtaaca gttgttactt atggaaaaat gcttcgccgt
     9001 gtggttcaag ctgctgaaga attagcagaa gaaggaattt cagttgaaat tgttgaccca
     9061 cgtacccttg ttccgcttga taaggatatc atcataaact cagtgaagaa gactggtaag
     9121 gttgttctgg tcaacgatgc ccacaaaaca agtggctata tcggtgaaat ttcagctatt
     9181 atttcagaat cagaagcatt tgactatcta gatgcaccaa tccgccgttg tgcaggagaa
     9241 gatgtgccga tgccttatgc acaaaaccta gaaaatgcaa tgattccaac agttgaaagt
     9301 atcaaagatg caatccgaaa aacttataac aaagactaga gttacataag ataagttatg
     9361 taaataaaac aaagctgacg agaaactttg tatcttttag gtgcagagct cttcgtcatt
     9421 aatatcttag attagagcac gggctaaaag ctcggaaaaa agataaatct ccttggcttc
     9481 atcgaagcca tcgtcgattt cctatttttc agtcgctttt gacgcccttt gtatcataaa
     9541 tagaattgga gaggtcatgg ctgatgacaa gctaagagcg actcctgcag ctagaaagtt
     9601 agcggatgat ttagggataa acctctacga cgtttctggc tcaggtgcaa acggtcgtgt
     9661 ccacaaagaa gacgtggaaa cttataaaga cacaaacgtg gttcgcattt cgccacttgc
     9721 aaaacgaatt gccctcgaac ataacattgc ttggcaggaa atccaaggaa ccggtcatcg
     9781 tggtaaaatc atgaagaagg atgttttggc cctgcttcct gaaaatatcg aaaacgatag
     9841 catcaaatct cctgctcaga ttgaaaaagt ggaagaagtc cctgataacg taacaccata
     9901 tggtgaaatc gagcgtattc caatgacacc aatgcgtaag gttattgccc aacgcatggt
     9961 tgaatcttac ttgactgcgc caaccttcac cctaaactat gaagttgata tgactgaaat
    10021 gttggctctt cgtaagaagg ttcttgagcc aatcatggaa gcaactggga agaagactac
    10081 tgtaacagac cttctttcac ttgcagttgt taagactctt atgaaacacc catacatcaa
    10141 cgcttcattg acagaagatg gcaagactat tatcactcac aactatgtca atcttgccat
    10201 ggcagttggg atggataatg gattgatgac acctgttgtt tacaatgctg agaagatgag
    10261 tctttcagaa ctggttgtag cctttaagga tgttattggt cgtaccttgg atggtaaatt
    10321 ggctccaagt gagttacaaa attcaacatt cacaatcagt aatttgggaa tgtttggtgt
    10381 tcagtccttt ggtccgatta ttaaccaacc caactcagct atccttggtg tcagttcgac
    10441 aatcgagaag ccagttgtcg tcaatggtga aattgtgatt cgcccaatca tgagtttagg
    10501 attaaccatt gaccaccgtg tcgtagatgg tatggctggt gctaagttta tgaaggactt
    10561 gaaagagttg attgaaacgc caatctcaat gttaatttaa gagcaagagt attcattttt
    10621 aagatataga taaaggaagg aagacatggc cttagaagta attatgccaa aagccggcgt
    10681 ggatatgaca gaaggacaaa tcgtccaatg gaataaaaaa gtcggagaat ttgtaaaaga
    10741 aggagaaatc cttttggaaa tcatgactga taaagtcagc atggaattgg aagccgaaga
    10801 agatgggtac ttgattgcca ttctcaaagg agatggtgaa actgtccctg taacggaagt
    10861 tatcggttac cttggtgaag aaagggaaaa catcccaaca gctggagcag catcgccaga
    10921 agctagccct gtacctgtag caagtacctc aaacgatgat ggtaagagcg atgatgcttt
    10981 tgatatcgtt gtgattggtg gaggtcctgc tggttatgtt gcagccatta aagctgccca
    11041 actcggcggt aaggttgccc ttgttgagaa atctgaactt ggtggaacct gcttaaaccg
    11101 tggatgtatt ccaaccaaga cctaccttca taacgctgaa attattgaaa atatcggtca
    11161 tgctgcaaat cgtggtatcg tgattgaaaa tcctaacttc actgttgata tggaaaaact
    11221 tttagaaact aaatctaaag ttgttaatac tcttgttggt ggtgttgcag gacttcttcg
    11281 tagctacgga gttactgttc ataaaggaat tggtacaatc actaaagaca agaacgtctt
    11341 ggtaaatggt tctgaattgc ttgaaaccaa gaaaatcatt cttgctggtg gttcaaaagt
    11401 cagcaagatc aacgtccctg gtatggaatc tccacttgtc atgactagtg atgacattct
    11461 tgaaatgaac gaagtgccag aaagccttgt tatcatcggt ggtggagttg tcggtatcga
    11521 actcggtcag gccttcatga cgtttggttc aaaagtgact gttatcgaaa tgatggaccg
    11581 tatagttcca gctatggatg cggaagtttc taagaacctt cgcttgatcc ttgagcgtaa
    11641 aggaatgacc atcttgactg gtactaaact gcaagaaatc attgaggaaa atggtcaact
    11701 tcgtatcaag gttgaaggaa aagacgatat catagcaagc aaagctcttc tttcaattgg
    11761 tcgtatgcca gaccttgaag gtattggaga ggttgagttt gaattggatc gtggttgtat
    11821 caaggtcaat gaatacatgg aaacttcagt tccaggcatt tatgcaccag gtgacatcaa
    11881 cggtactaag atgttggctc acgcagcttt ccgcatgggt gaagtttccg ctgaaaatgc
    11941 ccttaaagga aatcatgcag ttgccaaatt gaatttgact cctgcagcca tctacactct
    12001 ccctgaagta gcagcagtag gtttgacaga agaacaagcc cgtgagaaat acgatgttgc
    12061 catcggtaag tttaactttg ctgctaatgg tcgtgctatt gcatctgacg cagctcaagg
    12121 tttcgtaaaa gttatcgctg ataagaaata cggagaaatc cttggtgtac acattattgg
    12181 tcctgcagcc gcagaattaa taaacgaagc atcaagcatc atcgaaatgg aaatcactgt
    12241 tgaggaaatg ctgaagacca tccacgggca cccaacttac tctgaagtga tgtacgaagc
    12301 gtttgcagat gttctaggaa tggccatcca ttcacctaag aaaaaataaa acgaagatag
    12361 attagactgg aaggttattt ccagtttcta tcatataaag taaagggata tcatgaaata
    12421 cattatcaat cattcaaatg acactgcttt taatattgcc ttggaagaat acgcctttaa
    12481 acaccttttg gatgaggatc aaatcttcct actttggatt aacaagccat ctatcattgt
    12541 tggtcgtcac cagaacacta tcgaagaaat caaccgtgat tatgttcgcg aaaatggtat
    12601 tgaggtagtt cgccgtatta gtggtggtgg agctgtttac cacgatttaa ataacctcaa
    12661 ctacacgatc atctccaaag aagatgaaaa taaggcattt gacttcaaga gcttctcaac
    12721 tccggttatc aataccctgg ctcaacttgg ggttaaagct gagttcacag gtcgtaatga
    12781 ccttgagatt gatggtaaga agttctgtgg taatgcccaa gcctatatca acggccgtat
    12841 catgcaccac ggttgcttgc tctttgacgt tgatttgtca gtcctcgcaa atgcccttaa
    12901 ggtttcaaaa gataaatttg aatcaaaagg tgtgaaatcc gtccgtgccc gtgtaaccaa
    12961 tattatcaat gaattaccaa aaaaaatcac agtcgaaaaa ttccgtgatt tactcttgga
    13021 atacatgaaa aaagagtacc cagagatgac tgaatacgtc ttttcagaag aagaattggc
    13081 cgaaatcaat cacatcaagg atactaagtt tggaacttgg gactggaact atggtaaatc
    13141 acctgaattt aacgtccgtc gtggaaccaa attcactagt ggtaaggttg aagtctttgc
    13201 taacgttact gaatcaaaaa tccaagacat caagatttat ggtgacttct ttggtattga
    13261 agacgttgct gcagtagaag atgtccttcg tggggtgaaa tacgaacgcg aagatgttct
    13321 taaggcgcta aaaaccattg atatcacacg ctacttcgct ggtattagcc gtgaagaaat
    13381 cgctgaagcg gtagttggat aaatcaaaaa gaagttggcc aactaaccaa cttctttttg
    13441 atatttattt acataattta aaatacgtaa aattataaac tatctagagc attcttttgt
    13501 tcatcattaa caatatgggt atagaggtca gtgacttgtg tgctggcatg tcctagttgg
    13561 tgactgacta aaacttgtga tttagtcgca tcatagagcc tagttgctag cgtatggcgc
    13621 agtttatggg gtgttacacg cactttaaaa tcctctgagt atttagcaac cattttctca
    13681 acgctagaag catcgatacg attaggaaca cctctgtaga gagttaaaaa aagggctgta
    13741 tctgtttttt ccgttttata gcgttgattc cgaatggcca gataattctc taaataaggt
    13801 ttagcaaaag cagcgacatt gactgagtca cgtttgccac cttttcgagt aacatcaata
    13861 accatcattt ttagattgag atctcttaga tctagattaa cagcttcaga taagcgaaca
    13921 ccagatgcca agagaagggc aataatggct aaatctcgtt ctttattttt gttgaatgat
    13981 gagagagctc gatttgaaag ctgttgtggg tgctcttgat cgatataagt tagaaaacct
    14041 tctgtttcat cacctagaaa gagtttttgc ttgatatttt cagctctggc agcaagggtt
    14101 tctttctttt tcttggttga aacttttttc attacattac gatagaaata aggttccccc
    14161 tgatcgtttt caacctcctc ggttagatac ttgtaaagac tagaaagtgc tgataaggtt
    14221 cgattgatag ttgtctgtga aacaccttgt tttgttgtat tagcattcag caagggacgt
    14281 tcacgtagat aaaggataaa ggattccatg tctttcttag acatattttc caaagctgat
    14341 aaaggaatat cggatatttt atcagcgttt gaaataccag actccaaaac ccagctgaaa
    14401 aatcggtcat attccttaag gtattcgtac agggttgtaa aactgtaggg tacagccagc
    14461 ttagattggt agtattccag aacataccag ggcatgagtt gttttagttt gtcgattcgt
    14521 tccagtaaaa tctcacgttt catgtatttt ctccataagt aagtatacta gtagtatagc
    14581 atagacttgt atatttttca agaaaattat agtttttcag aaagatgtta taggagtttt
    14641 tcaaagtgat aaaaagactt agacctacaa acaaaacaga ataaggaaaa tctcacccac
    14701 taaacttctg ttaatactac ataactgaag agctatataa ggagctatga gatacaaaac
    14761 acattgtata atagattgaa actagaatag tacatctgga cttctaaaac attgctagaa
    14821 attgatttga ttgtcctgat tgttttatcc tatttctatt tcatttcact atataattgc
    14881 tattgttttc tttttcatga ttttaatctt actgtacaga tttgatacag taaactcctt
    14941 tccagcttta tgctttatca tttctaactt aattatagtc ttatttttaa taaagttcaa
    15001 ttatttatat gtaaaattcc tcatcagtaa aaaataaccg atctcatttc tgagaatcgg
    15061 ttttctaaat aaatcaaact gatcatttac ataacataaa ttatgtgaat gatcatacta
    15121 caacaacaaa tctttgactt ttccaatttc actttttgga ataaccaggt gaatcatatc
    15181 acccagatac attctggttg agccgttaac tgtttggctc ttgccattat ggacttgagt
    15241 tgtgatgagg acgttgtgtg gtaagttgag ttcatgaact tgtttcccag caattttatc
    15301 agaaactggt atttcgataa gtgtaacttc tccttcgcta gatacttctt ctggaagcat
    15361 tttttccagc atggcttcat agactggcgt acctttgagc aaatccatga taatataaga
    15421 aacaagagtg acaagaccaa gtggcatgag gttgcgaata tctcctacca tctcagttac
    15481 gaggatcata gcggttaagg gagcttttga tatggctcca aaatagccac tcattcctag
    15541 aatgacaaat atagggaatt gctcttgact gacaagtcca agattgacac agataacacc
    15601 aactaaggca ccaagcaaag aaccaagagc taaaatgggt aggaaaattc ctcctggcag
    15661 tccacttcca tagctaatca tactccaaat aaagcggatc aaaaagtaag ctaataaaac
    15721 ttggaaacta aaattttgtt cagttaaaga aaggacaagc tgatttccgc caccaaggat
    15781 ttgaggtaag aagattccga ctggtatgat aaggataaaa gccaagatgg gataataagc
    15841 cctatccaaa tggatttttt gaccaatcaa gtcataaact cttccaacgt ttaatacagc
    15901 tttctcatag agaaaacctg aaaatccaag gaaaattccc atgacgagat atatccaata
    15961 ctggtctagg gtcatgggag gaatgttatc tgacatatcc aatactggtg tcaaaccgaa
    16021 catgagtaga gacacaaagt ttgctacgat gctggctgct agagttgaga cccagaaaaa
    16081 gcgcgaaaaa tggtgataga cttcttctac aacaaagaga agtgctgcaa taggagcatt
    16141 aaaggctgcg gctaaacctg ctgcagctcc actggcaatc aaggaacgtt cctctactgg
    16201 actggatttg agccacttgg caattccttt accaccaact gctccaagtt gaatgctggg
    16261 tccctctcga cccagcatga gtccactggc aatagcaaga atacctagca catatttttt
    16321 ccaaagaatg ccccaccagt tgagggacat gaggcctttc agttcggctt cgacttgagg
    16381 aattcctgag cctttaatat ctttttctga ccgtgttagt ttggcactga gccaacagat
    16441 gagtatataa aacaaaacca gtacaaaaag attgcgcact aagtaccctt gatcttgata
    16501 aactccttgt atcaggtgga agcccttttc aattaagaaa cgaaaggatc cgacgataat
    16561 tccaacgatg aggccgacaa tgattcctcg accaacttgg gatagtatag tgctggatgc
    16621 aaaggcgaat tctttcttag aacggactat ttccgactgt tcctccatgg tatttccttt
    16681 caattaactt tcttttttac ctaaaaccag tgatttaacg ggttcaaagc tggttcggtg
    16741 aattggggta actcctagtt ttgtgaggcc ttccagatgt ttagctgtgc catatcctgc
    16801 attagtagcg aaatcatagc cagagaactg ctgatcgtat tctttcatca attcatcacg
    16861 tgttaccttg gctactatag atgctgctgc gatagagagg gagttggcat ctcctttgat
    16921 aatggaggtt tgtgaaatgg gcaagtccag tttcatggca tcaatcaaaa ggtgctctgg
    16981 ttgagggctg agctgggaga ttgcttcttg catggctagt ttggttgctt catagatgtt
    17041 gacttggtcg atgacctgat tatctatgat accaattcca atcgacaagg cttggtcttg
    17101 aacggcttgg aaaatctcca gatgtttctt tttaggaatt ttcttgctgt cgttgagacc
    17161 tttaatctta caatttttag gtaaaataac ggccgcagcg actacaggac cagcaagagg
    17221 accacgacca acctcatcaa tacctgcaat taaggtcaat ccttgcttat aaagttcttt
    17281 ttcataagaa agcatggatt ccaagcgcaa attttcatct aattcagctt gaatggctct
    17341 tttacgcttg ctgatttcct tttgaactcc tgagcgatta tccttttcaa gatctaaaaa
    17401 aatagggctt tctaactcct tgactgtcac aaggagttct ttgatttctt taatcgttgc
    17461 catcgaggtc ttccaatgta tctaaggtat agttaccgag tttgccatca cggacttcct
    17521 tcacgaagag actgtaaaaa cggtcatagt catcacggaa accgagggcg cgggtcatat
    17581 ccataataat cacaggcgct tcttcttcaa ttttcatttg tttgaagcgt tcagccagct
    17641 tttctggata atgttctttg aaataattga taccaaaaat ggtaacctca tccataggaa
    17701 gcaactgatc cttgatagct ccagtcaatg ccaacttaag tgcaacagtt tcatcctcaa
    17761 acttaggcca gagaatcccc ggtgtatcca agatttccag atctttattg gttttaagcc
    17821 attgttgacc ttttgtgacc cctggcttgt ttccaacaac agcaatcttt ttaccagcca
    17881 aacggttcat cagagtggat ttaccagcgt ttggaatccc gataatcatg gtacgcaagg
    17941 tttcaatctg aatcccacgt tctttctggc gagcaatctt atcagccatg agcttcttgg
    18001 ccgcatctgt tacaactttt acagtcactt gctctttgga gttgatagct agcgtctgga
    18061 ttccttgtga ttcaaaatac tgacgccatt ccttggtcat tgctggatca gccaagtcgg
    18121 ccttgtttaa aatcaagagt tttggtttat caccaacaat cttggtcaac ataggatttt
    18181 gactagatag aggcaagcgt gcatctacta aaatcgtcac aaaatcaaca aattttaaat
    18241 tctcctgcac ctgtcgacga gctttagaca tgtgaccagg aaaccattga atagtagcca
    18301 ttgagttttt tcctttcata gcaaggattt agatccccta ttttatttta ctatagtttg
    18361 aacatagaga gttttcaaat gaatgatgtc caaacagttc ttgttttatg acatagaaat
    18421 ctactttata ttatatcatg ccttctttat tttgtccgat gatagccttt taccctatct
    18481 tttaccctat accctatcct ataccctata tagaaaaaag ccatcaaatg atgacttttc
    18541 agagggagca aaaaactgtc ctctttatgt tttaaacatt taacccaaat cattcatacc
    18601 tctctcaact agatgtaact tacaaaaccc ctgacctcat gagccacttt cttcctcctc
    18661 atgaggtcag ttttactttc tgctgttcca gtatcgtttt tcctcgctag atttcctcaa
    18721 aag
//
LOCUS       DBEROT010000041        18305 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.41, whole genome shotgun sequence.
ACCESSION   DBEROT010000041 DBEROT010000000
VERSION     DBEROT010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.41"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..161)
                     /locus_tag="ACL8CG_001720"
     CDS             complement(<1..161)
                     /locus_tag="ACL8CG_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1344274.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKY"
     gene            1337..2596
                     /locus_tag="ACL8CG_001721"
     CDS             1337..2596
                     /locus_tag="ACL8CG_001721"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS1344275.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2612..3163
                     /locus_tag="ACL8CG_001722"
     CDS             2612..3163
                     /locus_tag="ACL8CG_001722"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1344276.1"
                     /translation="MNVWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            3156..4433
                     /gene="spxR"
                     /locus_tag="ACL8CG_001723"
     CDS             3156..4433
                     /gene="spxR"
                     /locus_tag="ACL8CG_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGS1344277.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4449..5309
                     /locus_tag="ACL8CG_001724"
     CDS             4449..5309
                     /locus_tag="ACL8CG_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGS1344278.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5690..6494
                     /locus_tag="ACL8CG_001725"
     CDS             join(5690..6058,6060..6494)
                     /locus_tag="ACL8CG_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HGS1344279.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLTVLKTAYQLKHAKGG
                     RKPNLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            6686..8977
                     /gene="pcrA"
                     /locus_tag="ACL8CG_001726"
     CDS             6686..8977
                     /gene="pcrA"
                     /locus_tag="ACL8CG_001726"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGS1344280.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVTQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            9020..9700
                     /gene="radC"
                     /locus_tag="ACL8CG_001727"
     CDS             9020..9700
                     /gene="radC"
                     /locus_tag="ACL8CG_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGS1344281.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9697..10386)
                     /locus_tag="ACL8CG_001728"
     CDS             complement(9697..10386)
                     /locus_tag="ACL8CG_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS1344282.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(10404..11045)
                     /locus_tag="ACL8CG_001729"
     CDS             complement(10404..11045)
                     /locus_tag="ACL8CG_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGS1344283.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(11128..11343)
                     /locus_tag="ACL8CG_001730"
     CDS             complement(11128..11343)
                     /locus_tag="ACL8CG_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS1344284.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(11351..11698)
                     /locus_tag="ACL8CG_001731"
     CDS             complement(11351..11698)
                     /locus_tag="ACL8CG_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGS1344285.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11703..12818)
                     /locus_tag="ACL8CG_001732"
     CDS             complement(11703..12818)
                     /locus_tag="ACL8CG_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS1344286.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12828..13787)
                     /locus_tag="ACL8CG_001733"
     CDS             complement(12828..13787)
                     /locus_tag="ACL8CG_001733"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS1344287.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13900..14469)
                     /locus_tag="ACL8CG_001734"
     CDS             complement(13900..14469)
                     /locus_tag="ACL8CG_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGS1344288.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14597..15268
                     /locus_tag="ACL8CG_001735"
     CDS             14597..15268
                     /locus_tag="ACL8CG_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGS1344289.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            15252..16070
                     /locus_tag="ACL8CG_001736"
     CDS             15252..16070
                     /locus_tag="ACL8CG_001736"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGS1344290.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            16067..16963
                     /locus_tag="ACL8CG_001737"
     CDS             16067..16963
                     /locus_tag="ACL8CG_001737"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1344291.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            17007..17981
                     /gene="pta"
                     /locus_tag="ACL8CG_001738"
     CDS             17007..17981
                     /gene="pta"
                     /locus_tag="ACL8CG_001738"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGS1344292.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAVLKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         5439 a         3326 c         3991 g         5549 t
ORIGIN      
        1 tcatatttct tcattagact tccacaatca gggcaagatg gagcctcata atccagctta
       61 gcgataattt ctttgtgggt atccatattg atgatatcta gaatcttgat gtttgggtct
      121 ttaatatcga gcagttttgt gataaaatgt aattgttcca tatgattctt tctaatgatg
      181 gttttgtcgc ttttcattat aggtcatatg ggactttttt tctacaataa aataggctcc
      241 ataatatcta taggggattt acccactaca aatattatag aaccggattt tgtggtacga
      301 caggcatgta tagcaaactg aatctggaat agcacagcat atcttctaaa atattgttat
      361 aaattgattt gaatttcaaa attaaattgt ttgattctta tttcaatttg ttatagtata
      421 tctgatgtca aagttctcgg cgagtcaaat agcgattccc aagcctgact atcgtgaggt
      481 agcggattaa aatggtctgg ggatagaccg ttttaagtct gacgctggaa ataagaattg
      541 tcagaagaag ggatagcgaa atcgtggctc tacgaacagg aacgtgataa taaggcgtat
      601 atagcggata agagggcctc aaactctaaa gtccaaaaag gtagtcgtaa cctatatgcg
      661 taaatcacga gagtaattga attcgtacta agattttcta ttttcactgt aaccttttaa
      721 cgtccttata tcttgtatac acgaggaaag atgtacgact tatcccgtga ggtctatcac
      781 tataaagaga aaacgacaga tagaagcgat cctgagtcac ggttatcttt aaaatagatt
      841 gtctgatagg atgctagcct gaaaacgtct tgttcatgaa atatagggac ggtatgtata
      901 aaacgcttct gtgaactgag agaaggggga gaagttcttg ataaaattta gttgaacagc
      961 cgtattccga tacttagata agagatctag tcttagctcc tactcggttt cagaggataa
     1021 aaaagggcaa tagcgattcg agaaagatta tactcttcga aaatctcttc aaatcacgtc
     1081 aatatcgcct tgccgtacgt gtaggatact gactacgtca gttccatcta caacctcaaa
     1141 acagtgtttt gagcaacctg cggctagttt cctagtttga tctttgattt ttattgagta
     1201 ttagtaattc agttactaac tcgtcaactc tgatttatcc aataaaattg aaaaggatgg
     1261 aaaaaaggat aaatttatga tatactttat tttgaagacc ttattagaaa tcttgaaaga
     1321 gtattgaaaa cttagaatga gaaaaattgt tatcaatggt ggattaccac tgcaaggtga
     1381 aattactatt agtggtgcta aaaatagtgt tgtggcctta attccagcta ttatattggc
     1441 tgatgatgtg gtgactttgg attgtgttcc agatatttcg gatgtagcca gtcttgtcga
     1501 aatcatggaa ttgatgggag ctactgttaa gcgttatgac gatgtcttgg agattgatcc
     1561 aagaggtgtt caaaatattc caatgcctta tggtaaaatt aacagtcttc gtgcatctta
     1621 ctatttttat gggagcctct taggccgttt tggtgaagcg acagttggtc taccgggagg
     1681 atgtgatctt ggtcctcgtc cgattgactt acaccttaag gcgtttgaag ctatgggtgc
     1741 cactgctagc tacgagggag ataacatgaa gttatctgct aaagatacag gacttcatgg
     1801 tgcaagtatt tacatggata cggttagtgt gggagcaacg attaatacga tgattgctgc
     1861 agttaaagca aatggtcgta ctattattga aaatgcagcc cgtgaacctg agattattga
     1921 tgtagctact ctcttgaata atatgggtgc ccatatccgt ggggcaggaa ctaatatcat
     1981 cattattgat ggtgttgaaa gattacatgg gacacgtcat caggtgattc cagaccgcat
     2041 tgaagctgga acatatatat ctttagctgc tgcagttggt aaaggaattc gtataaataa
     2101 tgttctttac gaacacctgg aagggtttat tgctaagttg gaagaaatgg gagtgagaat
     2161 gactgtatct gaagacagca tttttgtcga ggaacagtct aatttgaaag caatcaatat
     2221 taagacagct ccttacccag gctttgcaac tgatttgcaa caaccgctta cccctctttt
     2281 actaagagcg aatggtcgtg gtacaattgt cgatacgatt tacgaaaaac gtgtaaatca
     2341 tgtttttgaa ctagcaaaga tggatgcgga tatttcgaca acaaatggtc atattttgta
     2401 cacgggtgga cgtgatttac gtggggccag tgttaaagcg actgacttaa gagctggggc
     2461 tgcactagtc attgctgggc ttatggctga aggtaaaact gaaattacca atatcgagtt
     2521 tatcttacgt ggttattctg atattatcga aaaattacgt aatttaggag cggatattag
     2581 acttgttgag gattaaaccg tagaggtgtt tatgaatgtt tggaccaaat tagcaatgtt
     2641 ttcttttttt gaaacggatc gcttgtattt gcgtcctttc ttttttagtg atagtcagga
     2701 cttccgcgag atagcttcaa atccagaaaa tcttcaattt attttcccaa cgcaggcaag
     2761 tctggaagaa agtcaatatg cactggccaa ttactttatg aagtcccctt tgggagtgtg
     2821 ggcaatttgt gaccagaaaa atcaacaaat gattggttct attaaatttg agaagttaga
     2881 tgaaatcaaa aaagaagctg agcttggcta ttttttgaga aaagatgctt ggtcgcaagg
     2941 atttatgaca gaggttgtta gaaaaatttg tcagctttct tttgaggaat ttggcttaaa
     3001 acaattatct atcattaccc accttgaaaa tgaagctagc caaagagttg ctcttaagtc
     3061 tggatttagt ttgttccgtc agtttaaggg aagtgatcgt tacacaagaa aaatgcggga
     3121 ttatcttgaa tttcggtatg taaaaggaga gttcaatgag taagcatcag gaaattctaa
     3181 gctatttgga ggaattacca gtaggtaaaa gggtcagtgt tcgtagcatt tcgaatcatc
     3241 taggagttag tgatggaaca gcctatcggg ctattaaaga agctgaaaac cgtggaattg
     3301 tggagacccg tcctagaagt ggaacaattc gtgttaaatc ccagaaagtt gctatagaga
     3361 gattaacgtt tgctgaaatt gcagaagtga cttcttctga ggttctggct gggcaagaag
     3421 gtttagagag agaatttagt aagttttcaa ttggtgccat gactgaacaa aatatcttgt
     3481 cttaccttca tgatgggggg ctcttgattg tcggagaccg aacccgtatt cagttgctag
     3541 ccttggaaaa tgaaaatgca gttctggtta cagggggatt tcaggttcat gatgatgtgc
     3601 ttaaactggc caatcaaaaa gggattcctg ttctaagaag taagcatgat acctttaccg
     3661 tcgcgaccat gatcaataaa gccttgtcaa atgtccaaat caagactgat attctgacag
     3721 ttgagaaact ttatcgccct agtcatgagt atggttttct gagagagaca gatacagtta
     3781 aagattattt ggacttggtt cgtaagaatc gtagcagccg tttccctgtt atcaatcaac
     3841 atcaggtcgt tgttggcgtt gtaaccatga gagacgctgg tgataaatca ccaagcacga
     3901 caattgataa ggttatgtct cgtagtctat ttttggttgg attatcgaca aatattgcca
     3961 atgtgagtca acggatgatc gcagaagact ttgaaatggt accagttgtt cgaagcaatc
     4021 aaactttgct tggcgttgtg acgcgacgag atgtcatgga gaagatgagc cgttcccaag
     4081 tttcggctct accaactttt tctgagcaga ttggacaaaa gctctcttat caccatgatg
     4141 aagtagtcat tacagtggaa ccctttatgc tagaaaaaaa tggagttttg gctaatggtg
     4201 tattggcaga aattctgacc cacatgaccc aagatttagt tgttaatagt ggtcgcaatc
     4261 tcattatcga gcagatgctg atctactttt tgcaggctgt tcagatagat gatatattgc
     4321 gcattcaggc acggattatt catcatacga gacggtcagc tataattgat tacgatattt
     4381 atcatggtca ccagattgtt tcaaaagcaa atgtgactgt taaaattaat tagaaactag
     4441 gagaaaagat gataacatta aaatcagctc gtgaaatcga agctatggac aaggctggtg
     4501 attttctagc aagtattcat ataggcttac gtgatttgat taagccaggc gtagatatgt
     4561 gggaagttga agaatatgtc cgccgtcgtt gtaaagaaga aaatttcctt ccacttcaga
     4621 ttggggttga cggtgccatg atggactatc cttatgctac ctgttgctct cttaacgatg
     4681 aagtggctca cgctttccct cgtcattata tcttgaaaga tggtgatttg ctcaaagttg
     4741 atatggtttt gggaggtccc attgctaaat ctgacctaaa tgtctcaaaa ttaaacttca
     4801 acaatgttga acaaatgaaa aaatacactc agagctattc tggtggttta gcagactcat
     4861 gttgggctta tgctgttggt acaccgtccg aagaagtcaa aaacttgatg gatgtaacca
     4921 aagaagctat gtacaagggt attgagcaag ctgttgttgg aaatcgtatc ggtgatatcg
     4981 gtgcggctat tcaagaatac gctgaaagtc gtggttacgg tgtagtgcgt gatttggttg
     5041 gtcatggtgt tggcccaact atgcacgaag aaccaatggt tcctaactat ggtattgcag
     5101 gtcgtggact ccgtcttcgt gaaggaatgg tcttaaccat tgaaccaatg atcaatacag
     5161 gcgattggga aattgataca gatatgaaaa ctggttgggc gcataagacc attgacggtg
     5221 gattgtcatg tcagtatgaa caccaatttg tcattacgaa agatggacct gttatcttga
     5281 ctagccaagg tgaagaagga acttattaat aaaaagtgaa aagactactg gaagtttatt
     5341 ttgataaaaa atccagtaga tcttttcata ataaaacgca ttgtatcaag tgttaggggc
     5401 tgatatcatg cgtttttctg cttttaagat tttttccaac tctgtttgta agcgcatcat
     5461 aacaaagggt ctaggattca gggctctcct cctatatact attagtaaag taaaactaag
     5521 ggaggatatt ttagtgtcgc agtctattgt tcctgtagag attccacaat attgtcgttt
     5581 tgattctaaa aagagaaatg gaattctgtt taatgttcgt attgccaatc ttaaatttac
     5641 cttttttaga ttagacttcc tgcgaaacaa aatatggtat agtagttcca tgaattatga
     5701 agcaagtaaa caactaactg atgcacgatt taagcgtctt gttggtgttc agcgcacgac
     5761 ttttgaagag atgttaactg tattaaaaac agcttatcaa cttaaacatg caaaaggtgg
     5821 acgaaaacct aatttaagcc tagaagacct tcttatggcc actcttcaat atgtgcgaga
     5881 atatcgaact tatgaacaaa ttgcggctga ttttggtatt cacgaaagca acttactccg
     5941 tcggagccaa tgggttgaag taactcttgt tcaaagtggt tttacgattt caagaactcc
     6001 tctcagttct gaggacacgg taatgattga tgcgacggaa gtaaaaatca atcgccctaa
     6061 aaaaagaatt agcgaatgat tctggtaaaa agaaatgcca cgctatgaag gctcaagcga
     6121 ttgtcacaag tcaagggaga attgtttctt tggatatcgc tgtgaactat tgtcatgata
     6181 tgaagttgtt caaaatgagt cgcagaaata tcggacaagc tggaaaaatc ttggctgaca
     6241 gtggttatca agggctcatg aagatatatc ctcaagcaca aactccacgt aaatccagca
     6301 aactcaagcc gctaacagtt gaagataaag cctataacca tgcgctatcc aaggatagaa
     6361 gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aatgatttca acaacttatc
     6421 gaaatcatcg taaacgtttc ggattacgaa tgaatttgag tgctggtatt atcaatcatg
     6481 aactaggatt ctagttttgc aggaagtcta ttgaggtatt gagctagttt atgaaaaaat
     6541 tgggtgaaaa agtcgagtgt tttagaaacc cacagtgtag tattctagtt tcaatccact
     6601 atattttgct actccccgta aagtttctat tttccctgat ttctgatata atagaaatat
     6661 tgacttcaag agtaaggaag agaagatgaa cgcattatta aatggaatga atgaccgtca
     6721 ggctgaggcg gtgcaaacga cagaaggtcc cttgctaatc atggcagggg ctggttctgg
     6781 aaagactcgt gttttaaccc accgtatcgc ttatttgatt gatgaaaagc tggtcaatcc
     6841 ttggaatatc ttggccatta cctttaccaa caaggctgcg cgtgagatga aagagcgtgc
     6901 ttatagcctc aatccagcta ctcaggactg tctgattgcg accttccact ccatgtgtgt
     6961 gcgtattttg cgtcgcgatg cggaccatat tggctacaat cgtaatttta caattgtgga
     7021 tcctggtgaa cagcgaacgc tcatgaaacg tattctcaaa cagttgaact tggatcctaa
     7081 aaaatggaat gaacgaacta ttttggggac catttccaat gctaagaatg atttgattga
     7141 tgatgttgct tatgctgccc aagctggcga tatgtatacg caaattgtga cccagtgtta
     7201 tacagcctat caaaaagaac ttcgtcagtc tgaatccgtt gactttgatg atttgattat
     7261 gctgaccttg cgtctctttg atcaaaatcc tgatgttttg acctactacc agcaaaaatt
     7321 ccaatacatc cacgttgatg agtaccaaga taccaaccac gctcagtacc aattggtcaa
     7381 actcttggct tcccgtttta aaaatatctg tgtggttggg gatgcggacc agtctatcta
     7441 cggttggcgt ggtgctgata tgcagaatat cttggacttt gaaaaggatt accccaaagc
     7501 caaggttgtc ttgctggagg aaaattaccg ctcaaccaaa accattctcc aagcggccaa
     7561 cgaggttatt aaaaataata aaaatcgccg tcctaaaaat ctctggactc aaaacgctga
     7621 tggggagcaa atcgtttact atcgtgccga tgatgagctg gatgaggctg tatttgtagc
     7681 cagaaccatc gatgaactta gtcgcagtca aaacttcctt cataaggatt ttgcagttct
     7741 ctatcggact aatgcccagt cccgtacaat tgaggaagcc ctgctcaagt ctaacattcc
     7801 ttataccatg gttggcggaa ccaaattcta cagccgtaag gaaattcgcg atattattgc
     7861 ttatctcaac cttattgcta atttgagtga caatattagt tttgagcgta ttatcaacga
     7921 gcctaaacgt ggaattggtc taggtacagt tgagaaaatc cgtgattttg caaatttgca
     7981 aaatatgtct atgctggatg cttctgctaa tattatgttg tctggtatca agggtaaggc
     8041 agcccaatct atctgggatt ttgccaatat gatgcttgat ttgcgggagc agctagacca
     8101 cttaagcatt acagagttgg ttgagtccgt cctagaaaaa acaggttatg tcgatattct
     8161 taacgcccaa gcgactctag aaagcaaggc acgggttgaa aatatcgaag agtttctttc
     8221 tgttacgaag aactttgatg acaccacgga tgtgacagaa gaggaaactg gtctggacaa
     8281 actgagtcgt ttcttaaatg acttggcttt gattgccgac acagattcag gtagtcagga
     8341 gacatcagaa gtgaccttga tgaccctgca tgctgccaaa ggtctcgaat ttccagttgt
     8401 ctttttgatt gggatggaag aaaatgtctt tccacttagt cgtgcgactg aagatccaga
     8461 tgaattagaa gaagagcgcc gtctagccta tgtaggtatc acgcgtgcag agaaaattct
     8521 ctatctgacc aatgccaact cacgcttgct ttttggtcgt accaattata accgtccgac
     8581 tcgttttatt aacgaaatca gttcagactt gcttgagtat caaggtctgg ctcgtcctgc
     8641 aaatacaagc tttaaggcat catatagcag tggtagtatt tcctttggtc aaggtatgag
     8701 tttggctcag gctcttcaag accgtaaacg cggtgctgcc ccaaaatcaa tccagtcaag
     8761 cggtcttcca tttggtcaat ttacagctgg cgcaaaatca gcatctagcg aggcaaattg
     8821 gtccattggt gacattgctc tccacaagaa atggggagag ggaactgttc tggaagtttc
     8881 aggtagcggt gctaggcagg aattgaaaat caatttccca gaagtaggtt tgaaaaaact
     8941 tttagccagt gtggctccaa ttgagaaaaa aatctaattt tccatccttc tcacgaataa
     9001 taaagtgagg aggattttta tgtacagtat ttcattccaa gaagattcac tattaccaag
     9061 agaaaggctg gccaaggaag gagttgaagc gcttagtaac caagagttgc tagctatttt
     9121 actcaggaca ggaacacgtc aagctagcgt ttttgaaatt gcccaaaaag tcttgaacaa
     9181 tctttcaagc ctaacggatt tgaaaaaaat gaccctgcag gaattgcaga gtttgtctgg
     9241 tattgggcgt gttaaggcca tagaattaca agctatgatt gaactggggc atcgtattca
     9301 caaacacgag actcttgaaa tggaaagtat tctcagcagt caaaagttgg ccaagaagat
     9361 gcagcaggaa ttaggggata aaaaacaaga gcacctggtg gcactctatc tcaatactca
     9421 aaatcaaatc atccatcagc agaccatttt tatcggttct gtaactcgta gtatcgctga
     9481 accgcgagag attctgcact atgcaatcaa gcatatggcg acttctctta tcttggtcca
     9541 caatcatcct tcaggagcgg tagcgcctag ccaaaatgat gatcatgtca ctaaacttgt
     9601 taaagaagcc tgcgaactga tggggattgt tctcttggac catttgattg tctctcattc
     9661 taattacttt agttatcgtg aaaagacaga tttaatctaa agttcattaa cgacatagtc
     9721 aaagagtttc ttatctttgg gacgattttc aaaaagaagt tctggatgcc attggacacc
     9781 gagaaaggcg acatcatccg tactcatgac agcctcaatg ataccatctt taggatcatg
     9841 agccacaact tttaaatttg gtgctaagtc cttgatgctc tggtggtgga aggagttgat
     9901 atgagagatt tctccataga tttcttggag aacggtatct ggttctgtta ccaagcgttg
     9961 agttgtgtac tcaacagaag aatcctgcca atggtcttcg atatcttggt acaaagttcc
    10021 acccatggca acgttaaaga gttgggtacc acggcagaca gagaaaatgg gctttttctg
    10081 tttaatagct tccttgatga gggccagttc gaagatatct ctttgaaggt gatagtcatc
    10141 gctatcaatg gttttgggtt cgccataaaa ttttggatcg acattttgcc cacctgtcaa
    10201 gatgagcttg tcaatcaaac tgatatagtg gcaggccatt tcttgatcac caatcggtag
    10261 gatgatggga atccctccag catctttaac gccttcaaca aagccttttg ctgcgtagct
    10321 catcatgatg tcatcatctg gatgagcttt ttcgtttcct gtaatcccaa taactggttt
    10381 tttcataaaa tgattttcgc tttctaatcc tcttttcgca tgaagtagag gagggtttgg
    10441 agttcacttg tcaaatcgac atactgaacg accacgtctt ttggtaaatg cagatggact
    10501 ggtgaaaaac tgagaattcc tttcacacca gcatcaacca agagattagc aacctcttgt
    10561 gacttgacgc tgggaacagt taggatagca gtcttcacat cagcatcctt gattttatcc
    10621 ttgatctgag aaatcccgta aatgggaatc ccgtcaggag tttgggtacc gacttcagga
    10681 tggtcgtcta ggtcaaaggc catgataatc ttcatcttgt tacgttcgtg gaagcggtag
    10741 tggagaaggg catggcccat atttccaata ccaaccagca tgacattggt aatagagttg
    10801 tcattgagca aatcggcaaa aaatgtcatt agttttttga catcatagcc aaaaccacga
    10861 cgaccaagtt caccaaaata ggaaaaatca cgacgtacgg tcgctgaatc aataccgata
    10921 gcctctgcaa tttgcttaga gttggcacgt tcaatctttt ctgcatgaaa tctcttaaaa
    10981 attcgatagt agagagagag tctttttgct gtagcttttg gaatagcaaa ctgtttatct
    11041 ttcacaaaat cacaaccttt ctattcttct attgtataga aacattgtga aaaaatcaac
    11101 aaaaataaga aaaaactaag aaaaatctta gttttgatgt aaaaaatctg catgagatag
    11161 aaaacggtag aggtctccga ccagcccctg ataaactttt ttgcccctaa aagtcagaga
    11221 agtcacataa agtgtatctg gtaaggttac acatcctgac aaagtcaaca tgagagcctc
    11281 atgatcctca tacttgagag tacgctctac atgatagcag tccttatagg tcagttcaaa
    11341 cattttggct ctatctttcc gattttgtaa agacaccacg ttctaccaag ctatccatga
    11401 ggaagtagaa tttttcctga tgaatatggt ggtcttctga tttgaaaata tcaactagac
    11461 gaaggccaaa cttgtcagtg atattgattt tagcccctgt aagttccttg ttaatgatga
    11521 ttttgagttg gaagccttca ccgctgtttg gcactttttc caaaaggcga gtcagttcat
    11581 agttaccaac cttagtttca aaaaaggtgt tatctttgag ggtgaatttt ttaacagaag
    11641 ggctaagagt gtaatcgtaa cgacaatttt ttaactgaat gattttttca aatgccatat
    11701 ggctaacctc cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc ttcaacggta
    11761 ttttgtggcg acaaactgat gcgaagggat tccttcaagc gttctgaatt tgcgccatac
    11821 atggctttaa gaacatggct ggattggaca acgcctgcag tacaggctga gccagtagag
    11881 attgaaattc cagctaaatc tagccgaagg agtaagaggt catttttctg accaggaaat
    11941 ccaatattga gaacataagg gagatgatgt tttcctctat tcaagtaata ctgaatgccc
    12001 tccagctctg ccagaaaggc agtttctaga ttttgtacat gttgaaaatg ttcttcttgt
    12061 ttttctaggt cttcttttag ggctgcaacc atgcctacga tggcaggcag attttcagtt
    12121 cctgcacgtt ttttctgttc ctgatctccg ccatgtagat aggaatcaaa gtccatgcta
    12181 gatgcgtaga gaaaaccgat tcccttagga ccatggaatt tgtgggcaga agcagtgaga
    12241 aaatcaatgc ccaattcttc tgaatgaatt gggattttac caatagcctg aactgcatca
    12301 acatgatagg cagcagggtg ttgcttgagt atttggccaa tttcagcgat gggaagtagg
    12361 tttcctgtct cattattggc aaacatagta gaaaccaaaa tcgtatcgtc acgtaaagcc
    12421 ttttgaattt gctgggctgt gatttcttga ttttctggct ggataatggt tgcttcaaat
    12481 ccaaagtgtt gaaccaagta atcaattgtt tcaaggacag catggtgctc gatggcagtt
    12541 gtgatgatat gttttccttg ttcttggtga cgaagacagt agccaatgat ggtagtatta
    12601 ttgccttcag tcccaccaga agtgaaaaag atatgttgag gttttgtcct tagtaactgg
    12661 gctagttcct gacgggcttc tcgcaagagt ttgccagctt gacgaccatg accatgaata
    12721 ctagaaggat ttccgtgggt ttcttgcata accttggtca tagctgaaat agcaactgct
    12781 gacataggag tcgttgcagc attgtccaaa taaatcaaag aatcacctta tttcttttta
    12841 ttgtaggcaa agagtgggct gactggtttt ctttcgtgaa tacggacgat agcatcacca
    12901 attaactcac tagcagtgat gtagcataca tttttaggag ttttttcttt tgttgctact
    12961 gaatcagtca caagaatttc tttaatatta gtattgtcaa gaagctcagc agctccctcg
    13021 acgaagagac cgtggctaga aacagcataa atttctgtag ctccttcacg ttcaacgatt
    13081 ttagaagctt cagagaaggt acgtcctgta tttaaaatat catcaatcaa gatagctttc
    13141 ttaccttcaa catcaccaat aatataacct tcgttacgag ttgcatcgtc ttgagggtag
    13201 tcgataatgg cgataggagc atcaagatat tcagccaggc tacgcgcacg tttgacacct
    13261 gaatttttag ggctaacgac aacaacatct gaaccaagca atcctttatc gcagtaatgt
    13321 tttgcgaata ggggaacagt gaaaagatta tccactggaa tatcaaagaa accttgaacc
    13381 tgaacggcat gcaaatcaag agtcaggata cgatcaactc cagccttaac cagcatattg
    13441 gcaactagtt ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg acgtgcatag
    13501 ccaaaatatg gaaggacaac gttgatactg tgggcacttg cacgcacaca agcatcgacc
    13561 atgattaaca attccattag gtggttgttg acagggaaac ttgttgattg aatgatgtaa
    13621 acatcataac cacggacact ttcttcgata tttacttgga tttctccgtc tgaaaattga
    13681 cgtgatgata gttttccaag tgggacacca acagcttggg caattttttg tgcaatctct
    13741 tggttagagt tgagtgcgaa aagtttcatg ttttttctat ctgacattat agaccgtcct
    13801 ctgtaaactt tataaatcct agttatattt accttacata tatgaactgg gatttgtgta
    13861 tttttatctt ttctatttta ccaaaaaatg gagattattt cagctatttt tcatactttt
    13921 gacaaatcga accaattttg aaggagcttt ttggtaggaa atctgatttt tctctaaaaa
    13981 ttgtcggaaa tcctgtttgc cttgctcatg attttccact tcaagctcca attcgtaatc
    14041 tgttatatca aagtatcggc tctgatccag tgccatgaga ccaatagctg ttttcatttc
    14101 atagcgaagc gttgttagac aaccaagaac ctgccagttc ttactttgga taccatgttt
    14161 cgccaattca tccagtacta gcccttgagg aagttcttcc ttactcagat agttctcagc
    14221 atcttttagt tgcaattttt ggttgtattc catgtttcca acactctgcg ggactttgag
    14281 tgtcaactca gcccagtctt caaaggttcg aatgcgcata gcgactttct tttctcgcag
    14341 ttcaaaatca ggcgtgtcga tgtagtaatt tgtttgaaga acaggagtga cacctgtgaa
    14401 ctggtctttt agacgattgt attcatcttt tttcaatagt gttttcaatt caatttctaa
    14461 atgtttcatt tttcttacct ttttttatcg ttgaaagcgg atttatggta taataagcat
    14521 tgtatttatt gtatatgaat ctggagaaaa aatcaaagat atttttgacg gataatatga
    14581 gaacaaggga gaatatatga ccttagaatg ggaagaattt ctagatcctt acattcaagc
    14641 tgttggtgag ttaaagatta aacttcgtgg tattcgtaag caatatcgta agcaaaataa
    14701 gcattctcca attgagtttg tgaccggtcg agtcaagcca attgagagca tcaaagaaaa
    14761 aatggctcgt cgtggcatta cttatgcgac cttggaacac gatttgcagg atattgctgg
    14821 cttacgtgtg atggttcagt ttgtagatga cgtcaaggaa gtagtggata ttttgcacaa
    14881 gcgtcaggat atgcgaatca tacaggagcg agattacatt actcatagaa aagcatcagg
    14941 ctatcgttcc tatcatgtgg tagtagaata tacggttgat accatcaatg gagctaagac
    15001 tattttggca gaaattcaaa ttcgtacttt ggccatgaat ttctgggcaa cgatagaaca
    15061 ttctctcaac tacaagtacc aaggggattt cccagatgag attaagaagc gactggaaat
    15121 tacagctaga atcgcccatc agttggatga agaaatgggt gaaattcgtg atgatatcca
    15181 agaagcccag gcactttttg atcctttgag tagaaaatta aatgacggtg taggaaacag
    15241 tgacgataca gatgaagaat acaggtaaac gaattgatct gatagccaat agaaaaccgc
    15301 agagtcaaag ggttttgtat gaattgcgag atcgtttgaa gagaaatcag tttatactca
    15361 atgataccaa tccggatatt gtcatttcca ttggcgggga tggtatgctc ttgtcggcct
    15421 ttcataagta cgaaaatcag cttgacaagg tccgctttat cggtcttcat actggacatt
    15481 tgggcttcta tacagattat cgtgattttg agttggacaa gctagtgact aatttgcagc
    15541 tagatactgg ggcaagggtt tcttaccctg ttctgaatgt gaaggtcttt cttgaaaatg
    15601 gtgaagttaa gattttcaga gcactcaacg aagccagcat ccgcaggtct gatcgaacca
    15661 tggtggcaga tattgtaata aatggtgttc cctttgaacg ttttcgtgga gacgggctaa
    15721 cagtttcgac accgactggt agtactgcct ataacaagtc tcttggcggt gctgttttac
    15781 accctaccat tgaagctttg caattaacgg aaattgccag ccttaataat cgtgtttatc
    15841 gaacactggg ctcttccatt attgtgccta agaaggataa gattgaactt attccaacaa
    15901 gaaacgatta tcatactatt tcggttgaca atagcgttta ttctttccgt aatattgagc
    15961 gtattgagta tcaaatcgac catcataaga ttcactttgt cgcgactcct agccatacca
    16021 gtttctggaa ccgtgttaag gatgccttta tcggtgaggt ggatgaatga ggtttgaatt
    16081 tatcgcagat gaacatgtca aggttaagac ctttttaaaa aagcacgagg tttctaaggg
    16141 attgctggct aagattaagt ttcgaggtgg agctattctg gtcaataatc aaccgcaaaa
    16201 tgcaacgtat ctattggacg ttggagacta cgttaccatt gacattcccg ctgaggaagg
    16261 ctttgaaacc ttggaggcta ttgagcatcc attagatatt ctctatgagg atgaccactt
    16321 tctagtcttg aataaaccct atggagtggc ttctattcct agtgtcaatc actctaatac
    16381 cattgccaat tttatcaagg gttactatgt caagcaaaat tatgaaaatc agcaggttca
    16441 cattgttacc agactagata gggacacttc tggcttgatg ctctttgcca agcacggtta
    16501 tgcccatgca cgattagaca agcagttgca gaagaaatct atcgagaaac gctactttgc
    16561 tttggttaag ggagatggac atttggagcc agaaggggaa attattgctc cgattgcgcg
    16621 tgatgaagat tccattatta ccagacgagt ggctaaaggc ggaaagtatg cccatacttc
    16681 atacaagatt gtagcttctt atggaaatat tcacttggtc tatattcacc tgcacactgg
    16741 tcgaacccat caaatccgag tccatttttc tcatatcggt tttcctttgc tgggagatga
    16801 tttgtatggt ggtagtctgg aagatggtat tcaacgtcag gctctgcatt gccattacct
    16861 atccttttat catccatttt tagagcaaga cttgcagtta gaaagtccct tgccggatga
    16921 tttcagtaac cttattaccc agttatcaac taatactcta taaaaactgt ctcagagtat
    16981 aattattatc ttaaaggaga aaactcatgg aagtttttga aagtctcaaa gccaaccttg
    17041 ttggtaaaaa tgctcgtatc gttctccctg aaggggaaga gcctcgtatt cttcaagcaa
    17101 caaaacgctt agtaaaagaa acagaagtga ttcctgtttt gcttggaaat cctgaaaaaa
    17161 ttaaaattta tcttgaaatt gaaggaatca tggatggtta tgaggtcatc gaccctcaac
    17221 attatcctca atttgaagaa atggtttctg ccttggtgga gcgtcgcaag ggcaaaatga
    17281 ctgaagaaga tgtacgcaag gttttggttg aagatgtcaa ctactttggt gtgatgttgg
    17341 tttacttggg cttggttgat ggaatggtgt caggagcgat tcactcaaca gcttcaacag
    17401 ttcgtccagc tctacaaatc atcaaaactc gtccaaatgt aactcgtact tcaggagcct
    17461 tcctcatggt tcgtggtacg gaacgttacc tatttggaga ctgtgccatt aacatcaatc
    17521 cagatgcaga agccttggct gaaattgcca tcaactcagc aatcacagct aagatgtttg
    17581 gcatcgaacc taaaattgcc atgttgagct attctactaa aggttcaggg tttggtgaaa
    17641 gcgttgataa ggtcgttgaa gcaactaaaa ttgctcacga cttgcgtcct gaccttgaaa
    17701 tcgatggtga gttgcaattt gatgcagcct ttgttcctga aactgcagtt ctgaaagctc
    17761 ctggaagtac ggtagctggt caagcaaatg tcttcatctt cccaggtatc gaggcaggaa
    17821 atatcggtta caagatggct gaacgcctgg gtggctttgc ggctgtagga cctgttttgc
    17881 aaggtttaaa caagccagtt aatgatcttt ctcgtggatg taatgcagat gatgtttaca
    17941 agttgaccct catcacagca gctcaagcag ttcatcaata gtgaaaacta taaagtgata
    18001 tactatgcta tactgtagtt atgaaactat gtacgaaaag cactgccatt aattcctgag
    18061 aactaaatta ctgattggtg tcaaaaagga aaacttccaa gcgatgatat cctgtctata
    18121 cacgacctat agaaatctgt aatatacata tccgtaaaac gataaattcc ctttttgatt
    18181 ttaaatgagt atgaaaagag aattttttgg ctctttgtca actgtagtgg gttgaagaaa
    18241 agctaagctc gagaaaggac aaatttcgtc ctttcttttt tgatgttcaa agcgataaaa
    18301 atctg
//
LOCUS       DBEROT010000042        18095 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.42, whole genome shotgun sequence.
ACCESSION   DBEROT010000042 DBEROT010000000
VERSION     DBEROT010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.42"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            181..990
                     /locus_tag="ACL8CG_001739"
     CDS             181..990
                     /locus_tag="ACL8CG_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGS1344293.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            995..1696
                     /locus_tag="ACL8CG_001740"
     CDS             995..1696
                     /locus_tag="ACL8CG_001740"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS1344294.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1721..2638
                     /locus_tag="ACL8CG_001741"
     CDS             1721..2638
                     /locus_tag="ACL8CG_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HGS1344295.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2666..4207
                     /locus_tag="ACL8CG_001742"
     CDS             2666..4207
                     /locus_tag="ACL8CG_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HGS1344296.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4226..4684
                     /locus_tag="ACL8CG_001743"
     CDS             4226..4684
                     /locus_tag="ACL8CG_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS1344297.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4686..6908
                     /locus_tag="ACL8CG_001744"
     CDS             4686..6908
                     /locus_tag="ACL8CG_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004308 - exo-alpha-sialidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sialidase domain-containing protein"
                     /protein_id="HGS1344298.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6948..8057
                     /locus_tag="ACL8CG_001745"
     CDS             6948..8057
                     /locus_tag="ACL8CG_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS1344299.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            8214..9104
                     /locus_tag="ACL8CG_001746"
     CDS             8214..9104
                     /locus_tag="ACL8CG_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS1344300.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            9129..9452
                     /locus_tag="ACL8CG_001747"
     CDS             9129..9452
                     /locus_tag="ACL8CG_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344301.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            9442..11433
                     /locus_tag="ACL8CG_001748"
     CDS             9442..11433
                     /locus_tag="ACL8CG_001748"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HGS1344302.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            11449..11925
                     /locus_tag="ACL8CG_001749"
     CDS             11449..11925
                     /locus_tag="ACL8CG_001749"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HGS1344303.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11959..12540
                     /locus_tag="ACL8CG_001750"
     CDS             11959..12540
                     /locus_tag="ACL8CG_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344304.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            12605..13612
                     /locus_tag="ACL8CG_001751"
     CDS             12605..13612
                     /locus_tag="ACL8CG_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HGS1344305.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILES
                     TPYHLSIDILEDPSQTEISLMTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYG
                     S"
     gene            13602..13922
                     /locus_tag="ACL8CG_001752"
     CDS             13602..13922
                     /locus_tag="ACL8CG_001752"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HGS1344306.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            13985..15760
                     /locus_tag="ACL8CG_001753"
     CDS             13985..15760
                     /locus_tag="ACL8CG_001753"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HGS1344307.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            15761..17146
                     /locus_tag="ACL8CG_001754"
     CDS             15761..17146
                     /locus_tag="ACL8CG_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HGS1344308.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            17169..17780
                     /locus_tag="ACL8CG_001755"
     CDS             17169..17780
                     /locus_tag="ACL8CG_001755"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HGS1344309.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            17822..>18095
                     /locus_tag="ACL8CG_001756"
     CDS             17822..>18095
                     /locus_tag="ACL8CG_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344310.1"
                     /translation="MDKALSLSKLFLLTVSGYLFQNFGLLDNENVSTNLDLGLVNRKC
                     NYIESKRVITRYLSFMELLLYTISKVKLLEDILMPQPIVPVEIPQSR"
BASE COUNT         6116 a         2584 c         3596 g         5799 t
ORIGIN      
        1 ttcttacaat acatataatt acgataaaaa gaataaaaac tattatattt ttatgtttgt
       61 tgttctgtta tgaaacgaaa gaaattggaa actagtttct aatttatgaa aaatattgaa
      121 aaaaaaaaaa aaagtgttaa aataaagaat gtaaacgttt acttcaacta aggagctcat
      181 atgttactgc aaaaagaact aattccaatg atagaagcta acttaccaaa tatggcatat
      241 gctgaaaaag acattgctaa attcttctta aaacagcaac ctctgaatga ttattcatct
      301 aaagcattgt gcgaatacct taatgtatcc aaagcaacat tgactcgatt tgcgaaaaaa
      361 tgtggtttta aaggttttag acaattcatt ttcaaatacc aagagatgat tcatgagaaa
      421 gaaaagttgg cattatatac agaggcaaca gaaaaagttt tatccgacta tgaggaaatg
      481 ttgagaaaaa cttacacggt tcttgatgaa gttcaacttg agcgtattgc tgagatgata
      541 gaaactgctg agcgtgtata tctctacggt aaaggaagtt ctgttcttgc tttacaagaa
      601 atgaagatga gatttatgcg tctcggagtg attggtgaag tattatcaga cgaggatatg
      661 attttgtgga gtagcttact acttaatgaa aattgccttg tcattggagc atccatttca
      721 ggtcaaactg atattgtact agaaggtcta caaaaagctg cagataaagg cgctaaaaca
      781 gttttaatga ctacaagaaa atttgacgaa gaagattgtt tctttgatga actattgtta
      841 ttagcttcga ccgatcatct ctcgtatggc aatcgcatat cacctcagtt tccaatactt
      901 ttaattacag actgcttatt ctctaattat ctggaaagtc cagagagaca atattattac
      961 aatcaaacta ttatccataa ggaggaataa taaaatgagc caaatttgga ctaaagaaaa
     1021 atttataagc caagttcaag gtggagtcat tgtttcttgt caagctttac ctggtgaagc
     1081 cctttataat gaagaattta gcttgatgcc ttttatggct aaagcagctt tagaggcagg
     1141 agcagtgggc attcgcgcaa attctgtgcg tgatattaaa gcaattcaga aagtagtaga
     1201 tttaccaata attggaatta tcaaaaggga ttatccacct caagaaccat atattactgc
     1261 tacgatgaaa gaagtagatg aacttgtaga atgcggaaca acagtcattg catttgatgc
     1321 aactttaaga ccaagatatg atggcttagt tgtcagtgaa tttatcaaaa aaataaaaga
     1381 aaaatatccg aatcaattgc tgatggcgga tgtaagtaat ttagatgaag gtctctatgc
     1441 atttaaatca ggcgttgatt ttgttggtac aacattatca ggttacacaa gtacaagtgt
     1501 acaatcagat gagcctgatt ttgaactaat gaaaaaattg gctgatttta atattccggt
     1561 aattgccgaa ggaaaaattc attatccaga acaattaaaa aaagcttata gtttaggtgt
     1621 taccagtgta gtcattggtg gagcgattac acgtccaaaa gaaattgctc agcgatttat
     1681 taatgtcatc aaataaaaaa caatataaag gagaaatctg atgaaagatt taactaaata
     1741 caaaggcgtt atccctgcat tttatgcttg ctatgatgaa aatggtgaaa ttagccaaga
     1801 tcgtgtaaaa tctctggtac aatatttcat tgacaaaggt gtaaaaggta tctatgtaaa
     1861 tggttcttca ggtgaatgta tttaccaaag tgtagaagat cgtaaacaaa ttattgaagc
     1921 tgttatggaa gttgctaaag gtaaattaac agttatcaac catattgcat gtaataacac
     1981 gaaagatagt atcgaattgg caaaacattc agaaagtgtt ggagtcgatg ctattgcagc
     2041 tatcccacct atttatttca aattgccaga gtattcaatc gcagcatatt ggaatgcaat
     2101 gagtgaagct gcgtcaaata cagattttat tatctataat attccacaat tggcaggggt
     2161 tgcgttgact ggtagtttgt atgcaacaat gcgtcaaaat cctcgtgtga ttggagttaa
     2221 aaattcttct atgcctgtac aagatattca aatgtttgta gctgcaggtg gagaagatta
     2281 cattgtattc aatggtccag atgaacaata tcttggtggt cgcttgatgg gagcagaagc
     2341 tggtattggt ggtacttatg gcgttatgcc agatttgttc ttgaaattgg aaagtttgat
     2401 tcaagaacga gatttagata cagctaaaaa acttcaatat gctatcaatg aagttatcta
     2461 taagatgata tcaggtaagg caaatatgta tgctgtagca aaagaagttt tgcgtctaaa
     2521 tgaaaaactt gatttaggtt ctgttcgtca acctttagaa gcattggcag aaggtgactt
     2581 ggaagttgca aaacaagcag cagaacttat tcaacaagca cgaaaagaat ttttataata
     2641 aataaaatca atatggagat atgttatggg cacaacagga tttacaataa ttgacttaat
     2701 tatcttgatt gtttatttac ttgcggtgtt ggttgcaggt atctatttct ctaaaaaaga
     2761 gatgaaagga aaagagttct ttaaaggaga tggttcggtt ccttggtatg ttacttcggt
     2821 atccattttt gccacaatgc tcagtccgat ttccttcttg ggactcgctg gtagctctta
     2881 tgcaggtagc tggattttat ggtttgctca attagggatg gtagtagcta ttccactgac
     2941 aattcgtttt atcttaccta tctttgcacg gatagacatc gatacggcat atgattactt
     3001 ggataaacgt tttaattcta aagcacttcg tattatttca gcactcttgt ttattattta
     3061 tcaattggga cgtatgtcta tcattatgta cctcccatca gctggtttat cagtattgac
     3121 aggaattgac atcaatattt tgattatttt gatgggtgta gttgcaattg tttattctta
     3181 tactggtggt ctaaaatccg tattatggac agactttatt caaggtgtga ttctgattag
     3241 tggtgtcgtt ttagctttat ttgtactgat tgctaatatt aaaggtggct ttggtgcagt
     3301 agcagaaaca ttagcaaacg ggaaattcct tgctgcaaat gaaaaacttt tcgatcctaa
     3361 cttgctttca aactccatct ttttaattgt gatgggttca ggctttacaa tcttgtcttc
     3421 ctatgcttca tctcaagatt tggttcaacg ttttactaca acacaaaata ttaagaaact
     3481 taataagatg ttgttcacaa acggtgtttt gtcacttgca actgcaacag tcttttactt
     3541 gattggtaca ggcttgtacg tattctatca agtacaaaat gcagatagtg cagctagcaa
     3601 tatccctcaa gaccaaatct ttatgtactt tattgcatac cagttaccag taggtatcac
     3661 aggtttgatc ttggcagcga tttatgcagc atctcaatca actatttcaa caggtttgaa
     3721 ctctgttgca acttcatgga cattggatat tcaagatgtc atttctaaaa atatgtcaga
     3781 caatcgtcgt acgaaaattg cacaattcgt atctctagca gtaggtttat tctcaattgg
     3841 tgtttccatt gtcatggctc actcagatat taaatctgca tacgaatggt tcaatagttt
     3901 catgggactt gtacttggtc tacttggtgg tgtatttatt cttggatttg tttctaaaaa
     3961 agcaaataaa caaggtgctt atgcagcgct gattgtatca accatcgtca tggtatttat
     4021 taaatacttc cttcctccaa cagctgttag ctactgggca tattcattga tttcaatctc
     4081 tgtatcagta gtttcaggtt atattgtatc tgttcttact ggaaataaag tatctgcacc
     4141 taaatataca acgattcatg atattacaga aattaaagcg gattcaagtt gggaagttcg
     4201 tcactaatag aaaagagaaa ataatatgat tatttctgaa caatctgatt ttaaacgata
     4261 tgcttctgtc aataaatatt tttcaaaagt ctgtgatttt ttagaaaata caaatttgac
     4321 agatttagtt gatggaaaaa ttgatattga cggggaaaat gtttttgcaa attgtatgac
     4381 ttatctagct gatggagttc caggagatat ttttgaaact cataagaaat atttagatat
     4441 tcatattgtt gttgaaaata ctgaaaaaat ggcagtaact tccccagttc gtgcccagtc
     4501 acgtgtacct tttagcgaag agaaggatat tgctttttac gatagcaaag actatcaaat
     4561 tgttgaattg cttccaggga atatgttggt gacttttgaa gaagatcttc accaaccaaa
     4621 gattcattgc aatgatgaaa ctgttaaaaa acttgttatc aaagttttaa acgaggaaaa
     4681 ataaaatgaa aaaaaatatt aaacaatatg taaccttagg tactgtagtg gtattatcag
     4741 catttgttgc taactcagtt gcagctcagg agactgaaac ttctgaagta tcaacaccaa
     4801 agttggtgca acctgttgca ccaacgactc cgatttcgga agtacaacct acatcggata
     4861 actcttcgga agttactgta caacctcgaa cagttgaaac tactgttaag gatccatctt
     4921 ctacagcgga agaaactcct gtcttagaaa aaaataatgt tactttaaca gggggcggag
     4981 aaaatgttac taaagagtta aaggataaat ttactagcgg tgactttact gtagtgatta
     5041 agtacaatca gtcaagtgag aaaggcttac aagctctgtt tggaatatct aattccaaac
     5101 ccggtcaaca aaatagttat gtagatgtgt tccttagaga caatggtgag ttggggatgg
     5161 aagcgcgtga tacttcttcc aataaaaata acctagtatc cagacctgct tcagtttggg
     5221 gtaagtacaa acaagaggct gtgactaaca ctgttgcagt agtagcagat tcagtcaaaa
     5281 aaacatattc tttatacgca aatggtacaa aagtagtaga aaagaaagtg gataatttcc
     5341 taaacatcaa ggatattaaa ggtattgatt actatatgct tgggggagtg aaacgtgcag
     5401 gaaaaacggc gtttggtttt aacggaacac tagaaaatat caaattcttt aatagtgcat
     5461 tggatgaaga aactgttaaa aagatgacaa caaacgctgt tactggacat ttaatttata
     5521 cggctaatga tacaacaggt tctaactatt tccgtattcc agttctgtat acttttagca
     5581 atggtcgggt attttcaagc attgacgctc gttacggtgg aactcatgat ttcttgaata
     5641 aaattaatat tgctacaagt tatagtgatg ataatggtaa gacatggact aaaccaaaat
     5701 taacattggc attcgatgat tttgcgccag taccattaga atggcctcgt gaagttggtg
     5761 gacgtgactt acaaatcagc ggtggtgcaa cctatattga ctctgttatt gttgaaaaaa
     5821 agaacaaaca agtactcatg tttgctgatg tgatgcctgc tggagtaagt tttagagaag
     5881 caactagaaa agattcaggt tataaacaaa ttgatggtaa ttattacctt aaattaagga
     5941 aacaaggtga tactgattac aattatacta ttcgtgagaa tggtactgta tacgacgatc
     6001 gtaccaacag accaactgaa ttttcagtag ataaaaattt cggtattaaa caaaatggta
     6061 attatttgac ggtagagcaa tattcggttt catttgaaaa taataaaaag actgaatatc
     6121 gtaatgggac taaagtccat atgaatatct tctacaaaga tgcattgttt aaagtagtgc
     6181 caacgaacta tattgcatat atttctagca atgatcatgg cgaatcttgg tctgcaccaa
     6241 ctttattacc tcctataatg ggacttaatc ggaatgcgcc atatttaggt cctggacgtg
     6301 gaatcattga aagctcaact ggacgtattc ttattccgtc ttacactggt aaagagtctg
     6361 cgttcattta tagtgacgat aatggagcat cttggaaagt taaagtagtg ccacttcctt
     6421 ctagttggtc agcagaagca caatttgtag aattgagtcc aggagtaatt caagcatata
     6481 tgcgtacaaa taatggtaaa attgcatatt taacaagtaa agacgcaggt actacttgga
     6541 gtgcaccgga atatttgaaa tttgtttcaa atccaagtta tggaacacaa ttatcaatca
     6601 tcaattatag ccaattgatt gatggtaaaa aggctgtcat tttaagtact ccaaactcca
     6661 caaatggtcg taaacacgga caaatttgga ttggtctaat taatgatgat aatacaattg
     6721 attggcgtta tcatcacgac gttgattata gtaactatgg atactcatat tcaacattga
     6781 cagagttacc aaatcatgaa attggattga tgtttgaaaa atttgattca tggtctcgta
     6841 atgaacttca tatgaaaaat gttgtaccat atataacatt taagattgaa gatctgaaaa
     6901 agaattaaag ctgaaatttg aaaatatata aaaagaggat aaaaattatg gtaaattacg
     6961 gtattgttgg agctggatat tttggagctg atttagctcg ctcaatgaac aaaattgaag
     7021 atgcaaaagt ggttgcggta tttgacccaa atcatggaga agaagttgct caagagttgg
     7081 gatcagatgt ttgtgcaagt ttagatgaac ttgtagcacg tgaagatatt gattgtgtga
     7141 tcgtagcttc acctagctac cttcaccgtg aaccagttgt gaaagctgct caacatggca
     7201 aacacgtatt ttgtgaaaag ccaattgcat tgtcttatga agattgtaaa gccatggttg
     7261 acgcatgtaa agaaaataat gtcatcttta tggctggtca catcatgaac ttctttaacg
     7321 gtgtacacca tgctaaagaa ttgattactc aaggtaaaat cggtaaagtt ctttattgcc
     7381 atgctgctcg tacaggttgg gaagaacaac aaccaactgt atcatggaag aaacttcgtt
     7441 ctcaatctgg aggacatttg taccaccata ttcatgaatt agattgcatt cagtttatca
     7501 tgggaggact tcctgaaaaa gcgacaatgg taggaggcaa tgtatatcat aaaggtgaaa
     7561 actttggtga tgaagatgat atgctcattg taaacttaga atactctgat gatcgttatg
     7621 ctgttttgga atatggtaat gctttccgtt ggggtgaaca ctacgtcttg attcaaggaa
     7681 ctgaaggagc tatcaaactt gacttgttca atactggcgg tactcttcgt gttaaaggtg
     7741 aaggagaatc acacttctta gttcatgaaa ctcaagagga agatgatgat cgtacagcta
     7801 tctataccgg tcgtggtatg gatggagcaa ttgcgtacgg taaaccagga gtacgttgcc
     7861 cattatggtt gcaaacatgt attgataaag aaatggaata tctacatgac atcattaaag
     7921 gtggagaaat tacagaagaa tttgaaaaac ttctcaatgg tgtagctgct ttagaatcaa
     7981 tcgctaccgc tgatgcatgt actttatcag ttaaagaaga tcgaaaagta agtctttcag
     8041 aaatcacaaa tgcttaactt ttgtaaaaca gaatagtaaa ttcttgtcat tatataattt
     8101 ctaaagttct gtgatacaac tcattgaata aagaaataga gatgggactg ggataatgcc
     8161 cagtcccatt ttttatcaaa aagtaatgag atcaaaaatg tgggagtgtt gaaatgaaga
     8221 ttataggtat cgatattggc ggaacaacaa ttaaggcaga tttatacgat gagtttggaa
     8281 cgagtttgaa tcatttcaaa gagatagaaa caattattga ctatgatttg ggaacgaatc
     8341 agatattaaa tcaggtctgt gatttaattg gtgagtatac tttaaatcat tcaattgatg
     8401 gtgttgggat ttccactgct ggagttgtta atgctaatac tggagaaatc atctatgcag
     8461 gctatacaat accagggtat atcggagtaa actttactgc cgaaatagaa aaacgttttg
     8521 ggttgtatac ttttgttgaa aatgatgtta attgtgctgc attaggtgaa ttgtggaagg
     8581 gacaagccaa agataagaaa aatgtagtaa tggttactat tggaacaggt ataggaggca
     8641 gtattattgt caacggacaa attgttaacg gatttaacta tactgctggt gaagtaggtt
     8701 atattcctgt aggtaattcg gattggcaaa gtaaagcctc aacaaccgca ttgattcatt
     8761 tatatcaaaa aaagagcttg aaaactaatc aaactggacg tactttcttc actgatttaa
     8821 gatctggaga taaagttgct gaagaaactt ttgaaatttt tgtagaaaat ctaacaaaag
     8881 gtttattaac gatttcttat ctacttaatc cagaaattct catattagga ggtgggattc
     8941 tggatagtaa ggatattttg ttacctgaaa ttcaaagttc tttagctaaa aatgcaatgg
     9001 ataataggtt tttacctaaa aatcttgtgg cagctacatt aggaaatgaa gctggtcgta
     9061 taggagctgt aaaaaatttc ttagatagaa tttctaataa atagtatgta agataaggag
     9121 gtgtcacaat gactaactct gtattttcga caatgcaaga tattgagaat gttgcaaccg
     9181 atattataaa atcatatgat aatgagattt atacttataa agctgtttcc caagaagaat
     9241 tggaaaaact agaaaaaagt tatgatgaaa aaagtcacga agaattagtt tcaatagaaa
     9301 gcaatttaga aatgaaacaa cagaacctta ttgatgaggt taataaaaca atcaaggaaa
     9361 atgatgcaaa tattcagtat atttcatcaa gtaggagagg agaatttgta gaaaaaatta
     9421 ttggtagggt ggtagaaaaa tatggccatt agtcagatga aaagaatctc tctactattt
     9481 tctaaaagta gtcttgatga tgttttaaaa actattcaag aactagagtc agtgcagttc
     9541 cgtgatttaa aggttcagga taactggtca gaagctctag aaaaagatga agttgtattt
     9601 ccaactattc aaatttttca tacttctaat tccaatcatg gggttattga gggaaatgat
     9661 gccttgactt atttgatgaa tcaacaacaa catttagaag caactgtaga gaaattacaa
     9721 gaatacctac cgaaagaaaa cacgtttaaa ttattgcagc aacctccgat aactacctct
     9781 tatgaagaat tagagaaatt tggtaaagct aatgttgctg agggtgttct taaaaaagtg
     9841 aatcatcaaa ttaacagagt tcatgaatta gaaagacaca ttcaaagtaa taatgaggaa
     9901 atagagcgat taataaagtg ggaaaaatta gaaattgttc ctgcgaattt agaacaattt
     9961 tctttctgta aaggaaaagt cggaacaatt ccaaggactg aagataatcg cttatacaat
    10021 agtcttttag aaaacaatat tgaagttcaa gaaatatttt ctaatgatag agagtacggt
    10081 gttgttgttt tctatcagtc tagttactct atagattttg atgaatactt atttgaacca
    10141 tttgattatt ctagaaagga attaccgaag cagcgagtag tagatttaga tcaagaaaac
    10201 atgcagttaa taactgaaaa agagaatatt atcgcatcgt tgcaagattc aaagaaatat
    10261 ttgatagatt tacaatggca aatagactat attttatcta tctatgctcg tcaaatctct
    10321 aagaataact ttttgtgcac tccgcatcta gttgcattag aaggatggat agaagaaact
    10381 cgtattttat attttataaa agttatggat gagcattttg gacattctat ttatatttat
    10441 gaatcggaaa cattgacgga taatcaagat gaaataccta tcaaattaac gaatcattct
    10501 ttaattgaac catttgaatt attgacagaa atgtatgctc tgcccaaata ttatgagaaa
    10561 gatcctacac ctgtattagc accattttac tttacatttt ttggaatgat ggttgctgat
    10621 ttaggctatg gtttactatt gtttttagga acaatgttag cattaaaaat ttttcatcta
    10681 ccttcagcaa ctaagagatt tttaaaattc tttaatatat taggggtagc cgttgcaatt
    10741 tggggtggaa tctatggctc attttttgga tatgagttgc catttcatct gatatctaca
    10801 acctctgatg tcatgactat attagtagtg tcagttgtgt ttgggtttat tacagtattt
    10861 gcaggtttgt tagcttcagg actacaaaaa gtaagaatga agaaatatgc agaagcatat
    10921 aattcaggat ttgcgtggtg tgttattctg cttggcttgt tatttattgc tgttggaatg
    10981 ttgatgcctg atatgagacc gttatttgta ttagggaaat gggtatctat ttttaatgct
    11041 gtggggattt tgattgtttc tattattcaa accaaaagct tgtcaggtat tggagcagga
    11101 ttgtttaatc tatataacat ttcatcttat ataggtgatt tagttagttt cactcgattg
    11161 atggcattag gattatctgg agcaagtata gcatcagctt tcaatttaat tgttggtttg
    11221 tttccgggaa tattggctaa actgacaatt ggattagtat tattcattct tttacatgcg
    11281 atcaatattt ttctatcgtt actatcagga tatgttcatg gagcacgtct gatatttgtt
    11341 gaattttttg gtaagtttta tgagggtgga ggaaaaccat ttcaaccttt gaaggcttct
    11401 gagaaatata ttaaggttat tacaaagaat taatggagga tatatataat ggaacattta
    11461 gcaacttatt tttcaaccta tggaggagct ttcttcgctg cattgggaat tgtattggcg
    11521 gttggattaa gcggtatggg gtctgcttat ggagttggta aggctgggca atctgccgca
    11581 gctttactga aagaacagcc tgaaaagttt gcctcagctt tgatattgca attattgccc
    11641 ggaacacaag gattatatgg ttttgttatt ggaattttaa tttggttgca attaactcca
    11701 gaacttcctt tagaaaaagg cgttgcttat ttctttgtag ctcttccaat tgctattgta
    11761 ggatactttt cagctaagca tcaaggaaat gtagcagtag cgggaatgca aatcttggct
    11821 aaaagaccaa aagaattcat gaagggagca attttagctg ccatggtaga aacctatgca
    11881 attcttgctt ttgtcgtatc attcattttg acccttcgtg tataagaaat aaatttgcaa
    11941 ttcaaaggag gtgtctaaat gagcaattta gaaaacttac gagagtctgt tattgaacaa
    12001 gctcatgaaa aagggcgtat gaaattattg gattccaaaa agaagattga tgatgaattt
    12061 gaaatgcaaa agtcgctcat tataaagaaa aaagaagctg aacatgaacg aaagttaaaa
    12121 gaattgcaac agaaatatca aataattttt caacaattaa aaaataagga acgccaatca
    12181 acgttagtat caaaacagaa aatattaaaa gaactttttc aatctgcttt actagaaatg
    12241 gaatcttgga gtgcagataa agaaatggag ttcatctatc gaattctgga acgatattca
    12301 caacaagagg tcatagtaac ctttggggaa cggactttag ctaaattcaa tttggaacaa
    12361 ttagagaaat tgaaattctc ttttccaaat tatttattta gtgaacaacc tatctcaaat
    12421 gaatcaggct tacttatttc aataggtaaa attgatgata actatttgta taaaacatta
    12481 attggatcga tttctaagga agaaagttca agtatcgcaa atcaaatttt tatcaattaa
    12541 ggatgaaatt ggttaatcct tcttagaaat ttggagtatt ccaataaaat tagaaaggta
    12601 ttttatggat actaatcttt tttcaaaaat aaatacgacg atttcggtaa aagaaaacga
    12661 ttttattaca gaagaaaaat ttcaaaaaat tatacaatcc aaagatacgg agacattggc
    12721 atttatctta gaatcaactc cctatcattt atcgattgac atcttagaag atcctagtca
    12781 gacagagatt tcgctaatga caaaattagt caatgattat agatgggcct atgctgaaag
    12841 tccgtctgat ataattgtga ctttatttgc tttacgatat gtttatcata atatcaaagt
    12901 tttattaaaa tctaaggcgg caattaagaa agatttttct aaattattaa ttccaatagg
    12961 gatttttgat atagaaagtt taaaacattt agtttcttcc ttacattcag atacacttcc
    13021 tgattttatg gttcgtgaag tagaatcaat ttggaatgag tatgaaactt ttaataatat
    13081 tcgtgtactt gatgtcggag ctgatctagc atattttaaa catctgaaac ttttatctaa
    13141 tgagttagat gaggtactgt ctcaggttat tgtcgaaatg attgactttt ataatattat
    13201 tactgtaaaa cgtggtttat ctcaaaataa gagtcatggg gatattttac aattactttc
    13261 agatgaagga agtatttctg ctaaagaatt tatatacatt gtagaaaatc aagaaatatt
    13321 tgtgtggttc aataaaataa atccaagctt agattcaatc ttttcaactt atgaattgaa
    13381 gatgcaggac gcaacaattt catcttctga gttagaattt ttatgtgatt tactattgta
    13441 taaaacttta gatcaaggaa ggtacaatgt agaggggccg ttagttcttg ctagatattt
    13501 attgggatgt gagtttgaag taaagaatct cagaatgatc atatcagctc ttcaaaatac
    13561 aattcccttt gaatcaataa aagaaaggat acgcccacat tatggaagct aataagtata
    13621 aaattggcat aattggtagc cgtgatatta ttttaccatt tagcatgatt gggtttgata
    13681 tatttcctgc ctaccaagaa caagaagcta taaatacact aagaaaatta gctcaatctg
    13741 attatggtgt catttatatc actgaagaca ttgcttcaat gatattagat acaattcgcc
    13801 attatgattc ccaagttgtg cctgctatta ttttattacc gactcataaa caaggtttaa
    13861 atttaggatt aaaacgtata gaggataatg tagagaaagc agtaggacac aatattttat
    13921 aataatgtac aaaattgtct gtaatattat tctataattt ttggacttag taaggagaat
    13981 aactttgact caagggaaga ttataaaagt atcgggacct ctagttattg catcaggtat
    14041 gcaggaggct aatattcaag atatttgccg tgtaggtaag ctagggttaa tcggtgaaat
    14101 tattgaaatg agaagagatc aggcatctat ccaagtctat gaagaaacat ctggtcttgg
    14161 tccgggagaa cctgttgtta caactggaga acctctctcg gttgaattag ggccaggatt
    14221 gatttctcaa atgtttgatg gcatacaacg cccattagat cgatttaaat tggctactca
    14281 taatgatttt ctagttcgtg gggtagaagt tccaagtttg gatagagata ttaagtggca
    14341 ttttgattcc actatagcaa ttggtcaaaa agtgagtacg ggtgatattc ttggaactgt
    14401 caaggaaacc gaggtagtta atcataaaat tatggttcct tatggagtat ctggagaagt
    14461 cgtttctatt gcatctggcg attttacaat tgatgaagtt gtatatgaaa taaaaaaatt
    14521 ggacggtagt ttctataaag gaacgcttat gcaaaaatgg cctgtccgca aggcgcgtcc
    14581 tgtttctaaa cgtttaattc cagaagaacc attaatcaca ggtcaacgag ttattgatgc
    14641 attctttcca gtaaccaaag ggggagctgc agcagttcct ggaccgtttg gagcaggaaa
    14701 gacagttgta caacaccaag tagctaaatt tgccaatgtt gatattgtta tttatgtcgg
    14761 ttgtggagaa cgtggaaatg aaatgacgga tgtactgaat gagtttcctg agttgattga
    14821 ccctaatacc ggacaatcaa ttatgcaacg gacagttctg attgctaata cttcaaatat
    14881 gcctgttgct gctcgtgagg cttcaattta tacaggaatt accatggctg agtattttcg
    14941 tgatatgggc tactctgtcg ccattatggc tgattcaact tcacgttggg cagaagcgct
    15001 acgtgaaatg tcaggacgtc tagaagaaat gcctggtgat gagggttatc ctgcttatct
    15061 gggaagtcgt atcgctgaat attatgaaag agcaggacgt tctcaggttc tagggcttcc
    15121 agaacgtgaa ggaacgatta ctgctattgg agctgtatcg ccacctggtg gagatatttc
    15181 agaaccagtt actcaaaaca ctttacggat tgtgaaagtt ttttgggggc ttgatgctcc
    15241 gttggcacag cgacgtcatt ttcctgcaat taactggctt acatcttatt cactatataa
    15301 agacagtgtg ggcacttata tagatggtaa agagaagaca gattggaata gtaaaataac
    15361 tcgtgcgatg aactacttac aacgggaatc tagtttagag gaaattgttc gtcttgttgg
    15421 aattgattct ctgtctgata atgaacgact aacgatggaa attgctaaac aaattcgaga
    15481 agattatttg caacagaacg cttttgattc ggtagataca ttcacttcgt ttgcaaaaca
    15541 agaagcaatg ctaagtaata ttctcacttt tgctgatcag gcaaatcatg ctttagagtt
    15601 gggttcttac tttacagaga ttatggaagg taccgtggca gttcgagacc gtatggcgag
    15661 aagtaaatat gtttcagaag atagattaga tgaaatcaaa attatatcaa atgagattac
    15721 acatcaaatt catttgatat tagaaacagg aggtctataa atgagtgtta taaaagaata
    15781 cagaactgct agtgaagttg ttgggcctct tatgattgtt gaacaagtaa ataatgtgtc
    15841 ttacaatgag ttagttgaaa ttcaacttca taatggagaa attcgtcgtg gacaagtttt
    15901 agagatccac gaagataaag caatggttca gctttttgaa ggatctagtg gaataaattt
    15961 agaaaagtct aaaattcgtt ttgctggtca tgcattagaa ttggctgtat ctgaggatat
    16021 ggttggtcgt atttttaatg ggatgggaaa accaattgat ggtggaccag atttaattcc
    16081 agagaaatat ttagatattg atggtcaagc tattaatcct gtatctagag attatccaga
    16141 tgaatttatt cagacaggga tctcctctat tgatcatttg aatactcttg tacgtggtca
    16201 aaaattacca gtattttcag gttcgggctt acctcataat gaattagctg ctcagatagc
    16261 aagacaagcg actgttttaa attctgatga aaattttgcg gttgtatttg cagcaatggg
    16321 tattactttt gaagaagctg agttttttat ggaagaactc agaaaaacag gagcgatcga
    16381 tcgttcggtt ttatttatga acttggcaaa tgatcctgca attgagcgta ttgcaactcc
    16441 ccgcattgct ttaactgcgg cagagtatct agcttttgaa aaagatatgc acgttctagt
    16501 tatcatgacg gatatgacta actattgtga agcgttacgt gaagtctcgg cagctcgccg
    16561 tgaagttcca gggagacgag gctatccggg atatttatat acaaatttat caactctata
    16621 cgaaagggct ggtcgcttag ttggtaaaaa aggttcggtg acacagattc ctattttaac
    16681 aatgccagaa gatgacataa cacatccaat tcctgattta actggataca ttactgaagg
    16741 gcaaattatt ttgtcgcatg agttgtataa tcaaggttat cgtccaccaa tcaatgtttt
    16801 accttctctc tctcgattaa aagataaggg atctggagaa ggtaaaactc gtggagatca
    16861 tgctccaact atgaatcaac tgtttgcagc ctatgcccaa gggaaaaagg ttgaagagtt
    16921 agcagtagta ttaggagaat cggctttatc tgatgtagat aaattgtatg tgaggtttac
    16981 aaagcgtttt gaagaagagt acataaacca aggattttat aaaaatcgaa atatagaaga
    17041 tacgttgaat cttgggtggg aattactatc aattcttcct agaacagagt taaaacgtat
    17101 caaagatgat ttgcttgata aatacttacc tttggtagaa gtttaatccg gaaatggagt
    17161 gattatctat ggtacgtttg aatgtaaaac caactcgtat ggaattgaat aacttaaagg
    17221 aacgtttgac aacagctgaa cgtggacata agttattaaa ggataaaaga gatgaattga
    17281 tgaggcgatt tatttctttg attcgtgaga ataatcaact tcggaaagaa gtggaaagtt
    17341 atctaattga taatctaaaa tcctttgcag ttgctaaatc attaaagaat tctcaaatgg
    17401 tggaggaatt attttcaatt ccatcgaaag aaattgaatt atttgttgag aaagaaaata
    17461 tcatgagtgt aacagttcct agaatgcata tgaatattac ttctcaaaat gagaacagtg
    17521 aatacagcta tttatcttct aatagtgaaa tggatgatgt atttgctaca atgaatagtt
    17581 taatttataa attactaaga ctggcagaag ttgaaaaaac gtgtcagtta atggctgatg
    17641 aaatagaaaa aacacgtaga cgtgtaaatg gtttagaata ctcgattatt ccaaacttgt
    17701 cggaaactat tcattatata gaattgaaac tagaggaggc agaaagagcc aatttagttc
    17761 gtattatgaa agtgaagtag atcctttatt tagattatta attagatgaa caaatatcag
    17821 cttggataag gctttaagcc tttctaagct ttttttattg acagtatcag gatatctttt
    17881 tcaaaatttt ggtttgttag ataatgaaaa tgtttctact aatctagatt taggattagt
    17941 aaatcgtaaa tgtaattata tagaaagtaa gcgcgtcata acaaggtatc tatcattcat
    18001 ggagctcctc ctgtatacta ttagtaaagt aaaactattg gaggatattt taatgccaca
    18061 acctattgtt cctgtagaga ttccacaatc tcgtc
//
LOCUS       DBEROT010000043        17687 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.43, whole genome shotgun sequence.
ACCESSION   DBEROT010000043 DBEROT010000000
VERSION     DBEROT010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17687
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.43"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            5..92
                     /locus_tag="ACL8CG_001757"
     tRNA            5..92
                     /locus_tag="ACL8CG_001757"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Ser,seq:gct)
     gene            complement(218..1153)
                     /gene="birA"
                     /locus_tag="ACL8CG_001758"
     CDS             complement(218..1153)
                     /gene="birA"
                     /locus_tag="ACL8CG_001758"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGS1344311.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1150..2010)
                     /locus_tag="ACL8CG_001759"
     CDS             complement(1150..2010)
                     /locus_tag="ACL8CG_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS1344312.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2118..4280
                     /locus_tag="ACL8CG_001760"
     CDS             2118..4280
                     /locus_tag="ACL8CG_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGS1344313.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENQNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHTQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4372..5631
                     /locus_tag="ACL8CG_001761"
     CDS             4372..5631
                     /locus_tag="ACL8CG_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1344314.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5645..6511
                     /locus_tag="ACL8CG_001762"
     CDS             5645..6511
                     /locus_tag="ACL8CG_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1344315.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6525..7358
                     /locus_tag="ACL8CG_001763"
     CDS             6525..7358
                     /locus_tag="ACL8CG_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1344316.1"
                     /translation="MKQDERKALIGKYILLILGTVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7365..7505
                     /locus_tag="ACL8CG_001764"
     CDS             7365..7505
                     /locus_tag="ACL8CG_001764"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344317.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKATLTWFEEI
                     FE"
     gene            7716..9158
                     /gene="gtfA"
                     /locus_tag="ACL8CG_001765"
     CDS             7716..9158
                     /gene="gtfA"
                     /locus_tag="ACL8CG_001765"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGS1344318.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFRDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9296..10489
                     /locus_tag="ACL8CG_001766"
     CDS             9296..10489
                     /locus_tag="ACL8CG_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGS1344319.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11176..13155
                     /locus_tag="ACL8CG_001767"
     CDS             11176..13155
                     /locus_tag="ACL8CG_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1344320.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNVDKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13222..14718
                     /locus_tag="ACL8CG_001768"
     CDS             13222..14718
                     /locus_tag="ACL8CG_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344321.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14718..15644
                     /gene="oppC"
                     /locus_tag="ACL8CG_001769"
     CDS             14718..15644
                     /gene="oppC"
                     /locus_tag="ACL8CG_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGS1344322.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15653..16720
                     /locus_tag="ACL8CG_001770"
     CDS             15653..16720
                     /locus_tag="ACL8CG_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344323.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16731..17657
                     /locus_tag="ACL8CG_001771"
     CDS             16731..17657
                     /locus_tag="ACL8CG_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1344324.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
BASE COUNT         5205 a         3156 c         3708 g         5618 t
ORIGIN      
        1 aattggagaa ttactcaaga ggctgaagag gacggtttgc taaatcgtta ggtcgggtaa
       61 ctggcgcaag ggttcgaatc ccttattctc cgttttaatg agagtttgta actctctttt
      121 ttatttttag agccaataaa acttcagatc cgtaaaactt aattgaatta ctaatctgaa
      181 gttattttta tatcgtttat attataattg tgttatttta cttccaacta ttgagagaaa
      241 tttcgccact atttagccag atttcttttc cgttatcaca ttgaactaaa agttttccat
      301 tttctgagat gtctttagca agtcccttgt agtctttttg ctcgagtgtg aaagtgactt
      361 cttttcctag aatgaatgac tgttttttgt ataggtataa tagctcttct gctggtgttt
      421 cgaagaaagc acgccagatt tctatgatca attcattcct tgttatagga gctgtagctt
      481 taaataagct ggcagctttt tcttttaatt cctgagggaa gtctttaata gtgaaattga
      541 tacctactcc aataatgata tctgtgacta agccagtttc tacagaggtc attgcttcag
      601 taaggattcc tccaatttta tgattgttta gatagatatc attgacccat tttatgtcga
      661 catctattaa agttaggttc ttaatggctt tgtagacagc tccagctaca agtagtgtgt
      721 aggatggtaa tttgtcatag gggagatttg gtttaagatg gagtgtcata taaataccac
      781 cttgtggtga gtagaaggaa cgttgaaaac ggcctcggcc tgctgtttga taggaagcta
      841 gatagagggt atttgcttca tggcctaaat caattgcttc ttttgcatct agttgtgttg
      901 attttgtttc gggtttaaag ctgactttaa ttggaagatt ttcttctaga atctctggaa
      961 gaataaggtc accattcatc agtttatatc ctctattttt gatactatca atttcaatgc
     1021 cttcttgttc tagtcgcttg atggctttcc aaattgctgt tcggcttagg gatagttttt
     1081 ctgcgatttt ttctccgctg atatagtcgg tttctttaga taggatttgg tagacagctt
     1141 ggtaggattt cataatgttg cctttcttac tagttggtat tgagagtatt cttttcttgt
     1201 atgacttgga gtctgattaa agtattgttt ataagctttc gaaaaatgga gtggatctga
     1261 aaaacctacc gagtatgcaa ttaccttgat ggactcttgg gtattttcga gaagttgtct
     1321 agctcggtgc attcgaacgt agagtaggta ttctttgggt gataaggtat taaattcttt
     1381 gaatacgctt gataagtagc ttctgtgaac ggatagttct tttgctaaat cttgaattgt
     1441 aagtgattga ggatagtggc tatcaattaa tcgtttgcat tcaagataga gttggtgggt
     1501 tgatgaaata ttcttttttt tctgattggg agcaatagtt cccagatgaa acatcagttc
     1561 atgaagttgt cccatgatat ggagttgagc taattcactt gattttgtaa tctgagcgaa
     1621 gcggacaatg tctgagatga gttttgcagt agtctgggta tgacaagttt cagattggat
     1681 gagataggat tgatcagaaa tttgagaaag agcaaaataa tcaggggatt tccctccagt
     1741 gattcctaac cagtagtagg cccaaggttc tttactatct gcttgataaa aggttagttc
     1801 ctctggtttt aatagaaaga aatctccttc ttttaaatca acaattttac ccttgtaata
     1861 aaattttcct tgtcctttag taatgtaatg tagaacgtat gtatcacgaa tggctggacc
     1921 aaaagagtaa ttaggtgtgc attcctcata tccataaaag cttagggcaa ggtcgattgt
     1981 tccagtctgg tattctgaaa aaactaacat gtgctacctc ccacctaaca ttttaccata
     2041 ttcttgagac atttttctat tttggaaagc gatttcaggt gataaaatat aatcaataaa
     2101 gtgatgaggt gaagtaaatg ggagttagga tagagaataa tctattttat gttgagagta
     2161 aaaatctaag tttgattatt gaaaatcaaa atggctactt acttttgaaa catttaggaa
     2221 agactattaa gaactataaa ggttccaata gtgtttatga acgagaccat gccttttcag
     2281 gaaatccaac ggctactaat cgaaccttta gtttagatac tcagcgacag atttttggac
     2341 aacatggctt aggagatttt aggaaaccaa ccatacaggt tcagcatagt gtaactgaag
     2401 taacagactt tcgatttgta gaagcaaaga ttttaaaagg tcagaatggt ccacagggct
     2461 taccttctcc acatagcatg gacgatacag agactcttgt cttaatgtta gaagattcta
     2521 aggctcaact tagtctgact ttgtattata ctacttttaa taatgatgcg actattgcta
     2581 gctacagtaa attagataat aatagtaatc aggaagttgt catccataaa gatttttctt
     2641 ttatggctga ttttccagct gcagattacg aaatagtaac tctgcagggt gcttatgctc
     2701 gtgaaaagac tgttagacgt caacaggtag aacaaggaat cttttcgatt agctcaaacc
     2761 gaggtgcttc tggtcatact caaacaccag ctcttctact atgcgaacaa ggagtcacag
     2821 aggatgctgg gaatgtgttt gctattcaac taatgtatag tggcaacttt gaagcttttg
     2881 ttcaaaaaaa tcaattgaat gaagttcggg tggctattgg cattaatcca gaaaactttt
     2941 cttggaagtt agcccctgag gaatactttg aaacaccggt agctttagtg actcattcag
     3001 atcagggatt aactggtatt agtcatgaaa gtcagaattt tgtactgaag cacattatgc
     3061 taagtgaatt ttctaaaaaa gaacgtccaa ttctaatcaa taactgggaa gctacttact
     3121 ttgactttca gagagaaaaa ctgttagagt tagcagatga agctaagaaa gttggcattg
     3181 aactttttgt attagatgat ggttggtttg gcaatcgttt tgatgataat cgtgctttag
     3241 gtgattgggt tgttaatgag gaaaaactgg gtggaagtct agaaagtctg atttcagcta
     3301 tccatgaaag aggtttgcag tttggacttt ggttagaacc cgaaatgatt tctgtagata
     3361 gtgatttgta tcgtcgacat cctgactggg ctattcaggt tcctgactat gagcatactt
     3421 attctcggaa tcaattagta cttaatcttg ccaatcctca ggtagtagaa tacttgaaaa
     3481 gtgtcttaga tcaactccta tcttatcatg atattgatta cattaaatgg gatatgaacc
     3541 gcaatatcac taagctaggg aatggattaa cttatctaga gacacagatg caatctcatc
     3601 agtacatgct ggggctttac gaactcgttt cttatctgac agagaagcac agccatattc
     3661 tctttgagtc ctgctctggt ggtggtggac gaaatgatct tggtatgatg cgctatttcc
     3721 cacaagtctg ggctagtgat aatactgatg ccattgcacg tttaccaatt caatacggtt
     3781 catcctatct ctatccaacc atttctatgg gggctcatgt gtcagcagta ccaaatcatc
     3841 agatgggacg aatgacacca ttagaaacac gtggccttgt agcaatgatg ggaaatttgg
     3901 gctatgaact tgatttgaca aatttatcag atgaagagaa agctacgatt gctaatcagg
     3961 tgaacttgta taaagaatta cgaccagtag ttcagttagg acagcagtat agactaatta
     4021 atcctgatac tgcatccaat gaagcagctg tacaatttaa ttacggaaat caaacgattg
     4081 taacctacgt tcgcgtttta tctgttgtag agaccatgga aacaacttta aaattaaaag
     4141 atttggatga agagggacta tataaattac aggaaaatgg cgaagtttac tcaggtgcag
     4201 aactaatgta tgcgggctta actgttatct tatcccaagg agattttttg agtagacagt
     4261 atatttttag aaaactatga tatgtactga cctcaaaagt tagatttatt ctatctaact
     4321 tttgaggtgc agtttgataa gggtgtataa atttataaag gaggctttct aatggaatgg
     4381 tataaaaaaa tcggacttct tgcaactaca ggtttagctt tgtttgggct cggtgcttgc
     4441 tccaactatg gtaaatctgc ggatgacaca gtgaccatcg agtatttcaa ccagaaaaaa
     4501 gaaatgacca aaaccttgga agaaatcact cgtgattttg agaaggaaaa ccctaagata
     4561 aaggtcaaag tcgtcaatgt accaaatgct ggtgaagtat tgaagacacg cgttctcgca
     4621 ggagatgtgc ctgatgtggt caatatttac ccacagtcca tcgaactgca agaatgggca
     4681 aaagcaggtg tctttgaaga tttgagtaac aaagactacc tgaaacgcgt gaaaaatggc
     4741 tacgctgaaa aatatgctgt aaacgaaaaa gtttacaacg ttccttttac agctaatgct
     4801 tatggaattt actacaacaa agataaattc gaagaactgg gcttgaaagt tcctgaaacc
     4861 tgggatgaat ttgaacagtt agtcaaagat atcgttgcta aaggacaaac accatttgga
     4921 attgcaggtg cagatgcttg gacactcaat ggttacaatc aattagcctt tgcgacagca
     4981 acaggtggag gaaaagaagc aaatcaatac cttcgttatt ctcaaccaaa tgccattaaa
     5041 ttgtcggatc cgattatgaa agatgacatc aaggtcatgg acatccttcg catcaatggc
     5101 tctaagcaaa agaactggga aggtgctggc tataccgatg ttatcggagc cttcgcacgt
     5161 ggggatgtcc tcatgacacc aaatgggtct tgggcgatca cagcgattaa tgaacaaaaa
     5221 ccgaacttta agattgggac cttcatgatt ccaggaaaag aaaaaggaca aagcttaacc
     5281 gttggtgcgg gagacttggc atggtctatc tcagccacca ccaaacatcc aaaagaagcc
     5341 aatgcctttg tggaatatat gacccgtcca gaagtcatgc aaaaatacta cgatgtggac
     5401 ggatctccaa cagcgatcga aggggtcaaa caagcaggag aagattcacc gcttgctggt
     5461 atgaccgaat atgcctttac ggatcgtcac ttggtctggt tgcaacaata ctggaccagt
     5521 gaagcagact tccatacctt gaccatgaac tatgtcttga ccggtgataa acaaggcatg
     5581 gtcaatgatt tgaatgcctt ctttaacccg atgaaagcgg atgtggatta ggagtagaga
     5641 gactatgaaa aaagtattac aaaaatattg ggcatgggct tttgtggtca tccccctctt
     5701 gttacaagca attttcttct atgtgccgat gtttcaagga gccttttaca gttttaccaa
     5761 ctggacagga ttgacttata actacaaatt tgtcggctta aacaacttta agctcctctt
     5821 catggatcca aaattcatga atgcgattgg ctttaccgca atcattacga ttgccatggt
     5881 ggttggtgag attgcactcg ggatcttcat tgcgcgtgtc ttgaattcta aaatcaaagg
     5941 ccaaaccttc ttccgtgctt ggttcttctt cccagctgtt ttatctggtt tgacagtggc
     6001 tttgatcttc aagcaagtct tcaactacgg tcttccagcg attgggaatg cccttcatat
     6061 tgaatttctc caaaccagtc ttttagggac taagtgggga gcaatctttg cggctgtctt
     6121 tgtccttctt tggcaagggg tggctatgcc catcatcatc ttcctagctg gtttgcaatc
     6181 tattccaact gagattacag aggcagcaag gattgatggt gcgactagca agcaagtttt
     6241 ctggaacatt gaattgcctt acttgctacc aagtgtctct atagtcttta tcctagccct
     6301 aaaaggtggg ctgactgcct ttgaccaagt ctttgccatg accggtggtg gtccaaacaa
     6361 tgccacaacc tcacttgggc tcttggttta taactatgcc tttaaaaaca accaattcgg
     6421 ttatgccaat gccattgccg taatcttgtt cttcttaatt gtagtgattt cgatcatcca
     6481 attgagagta tctaagaaat ttgaaattta agaggagaag catgatgaaa caagatgaaa
     6541 gaaaagccct gattggcaaa tacattctat tgattctagg aacggttctg attttagtgc
     6601 cgctccttgc taccctcttt agttccttca aacccactaa ggatattgta gataatttct
     6661 ttggttttcc aaccaacttc acatgggaca actttagccg tctcttagct gatgggattg
     6721 gaggctatta ttggaactct gtcgtcatca ctgtcttgtc tttacttgca gtaatgatct
     6781 ttatccctat ggcagcctac tccatcgctc gcaatatgag taaaagaaaa gcctttacca
     6841 tcatgtatac cctcttaatc ctcggaatct tcgtaccttt ccaagtcatc atgattccga
     6901 ttacggttat gatgagtaaa ctcggtttgg ctaatacctt tggtttgatc ttgctctact
     6961 tgacctatgc gattccacag accctctttc tctatgttgg ctatatcaaa atctcgattc
     7021 cagaaagtct ggatgaagca gcagagatcg atggggctaa tcaatttaca acctatttcc
     7081 gcatcatctt cccaatgatg aaaccgatgc atgcgacaac catgatcatc aatgcccttt
     7141 ggttctggaa tgacttcatg ttgccactcc ttgtcttgaa ccgggattcc aaaatgtgga
     7201 ctctgccttt gttccaatac aactacgcag gccaatattt caacgactac ggaccaagct
     7261 ttgcctctta cgtggtcggc attatcagta tcaccattgt ctatctcttc ttccaacgcc
     7321 atatcatttc aggaatgagc aacggggcag tgaagtaata ctcaatgaaa atcaaagagc
     7381 aaactaggaa gctagccgca ggttgctcaa aacactgttt tgaggttgtg gatgaaactg
     7441 acgaagtcag taaccatacc tacggtaagg caacgctgac gtggtttgaa gagattttcg
     7501 aatagtataa gaagagctca tggaatctat agtctttgac acagaggaag agttcagctt
     7561 gttgataatt ctatgtagaa aacaagaaag tagtactttg tttatcacag tctatattag
     7621 tacgagtttg atgataaata gagatttaaa atgaatttta tttatgaagc cagatcatat
     7681 gagacttggc ttcaattaga aaaaggagag taatgatgcc aattcaaaat aaaaccatgt
     7741 tgattaccta ttctgatagc cttggaaata atcttaaaga cttatatgat aatttggaag
     7801 agcattttcg agatgctatt ggaggagttc accttttacc atttttccca tcaacaggtg
     7861 atcgtggatt tgcgccagtt gactacgacg aagtggactc agcttttggt gattgggagg
     7921 atgttaagcg tttaggtgag agatattatc ttatgtttga ttttatgatt aatcatattt
     7981 ctcgtcaatc caagtattat aaggactatc aagaaaaaca tgaagccagt gaatttaaag
     8041 ctctcttttt aaactgggat aagttttggc cagaaaaccg tccgacacag tctgatgtag
     8101 atttaattta caagcgtaag gatcgtgcac caaagcaaga gattgtgttt gaagatggtt
     8161 cagtggaaca tttgtggaat acctttggtg aagagcagat tgatcttgat gtgaccaaag
     8221 aagtaactat ggaatttatc cgtaagacca ttcagcactt ggcaagtaat gggtgtgatt
     8281 tgattcgtct agatgccttt gcttatgcag tgaagaaatt ggatactaat gatttctttg
     8341 tggaaccaga tatttgggat ttattggaca aagttcgaga tatcgctgct gagtatggga
     8401 cagagctttt acctgagatt catgaacact attcgattca gtttaaaata gcagaccatg
     8461 attactatgt ttatgatttt gctcttccaa tggtgacact ttatactctt tacagttcca
     8521 gaacagagcg tttggctaag tggttaaaga tgagcccgat gaagcaattt acgacgctag
     8581 atacccatga tgggattgga gtagtagatg tcaaggatat cctgaccgat gaggagattg
     8641 actatgcttc aaatgaactc tataaggttg gagccaatgt caaacgtaag tactctagtg
     8701 ccgagtataa caacttagat atctaccaaa tcaattcaac ctactattca gcgcttggag
     8761 atgatgatgt caagtatttt ctcgctcgtc taattcaagc ttttgcccca ggtattcctc
     8821 aggtttacta tgtgggtcta ttagcaggca agaatgactt gaaattatta gaagaaacta
     8881 aagaaggtcg aaatattaat cgtcattact atagcaacga ggaaatagca aaagaagtgc
     8941 aacgacctgt tgtgaaggcc cttctcaatc tattttcttt ccgtaaccgt tcagaagcct
     9001 ttgatctaga agggactact gagatagaga caccaacagc tcacagcatt gtaatcaaac
     9061 gtcaaaataa agataagtcc gtaacagcag tagtagaaat tgatttgcaa aatcagactt
     9121 atcgggtaat tgagaatgga gttgaagtat cattttgaag ccttgatatg gtggataaaa
     9181 tagggttttt attttggaaa acgtttcctt tgttttcaaa ttgctaaaaa agtggtacaa
     9241 tataggatag cttactatta tctgaatcag ctgatttgga gagaaaggat tcattttgaa
     9301 atcaataggc tttattgaaa agctgaaggg gttgtctagt aaagagctga ttttattggg
     9361 aattatccta agtatctttt taccctttta tctttttgta gttgtactct gtttatatat
     9421 tatcagtttg atttttacag gagacatgaa aagtattctt cagaaaatgg gggagcatcc
     9481 gatgctgctt ctttttctta gctatagtac tgttatatcc attcttgcac aaaattggat
     9541 gggtcttgtg gcttcagtag gaatgtttct atttactatt ttctttttgc actatcagtc
     9601 gattttatcc cataaattct ttcgattgat tttgcagttc gtcttgtttg gtagtgtctt
     9661 gtcagctgct tttgccagtt tagaacattt ccaaattgtg aagaaattta actatgcttt
     9721 tctttcaccc aatatgcagg tgtggcatca gaaccgggca gaagtgacct tctttaatcc
     9781 taattattat ggaattattt gttgtttctg tattatgatt gctttctatc tgtttacaac
     9841 gaccaagttg aattggttga aagtattctg tgtgattgca ggctttgtta atctctttgg
     9901 tttgaacttt actcaaaatc gaactgcctt tcctgctatt atcgctggag caattatcta
     9961 tctctttacg actattaaaa actggaaggc cttttggctt agtattgggg tcttcgcgat
    10021 tggtttgagt ttcctctttt ctagtgattt gggagttcga atgggtactt tagactcttc
    10081 tatggaagaa cgcatttcta tctgggatgc tgggatggcc ttgtttaagc aaaatccttt
    10141 ttggggtgaa gggccattga cctatatgca ctcttatcct cggatacatg ctccttatca
    10201 tgaacatgcc cacagtcttt atattgatac gattctgagt tacggaattg tgggtaccat
    10261 tttattagtt ttgtcttctg ttgctcctgt tcgcttgatg atggatatga gtcaggagtc
    10321 ggggaaacgt ccgattatcg gcctttatct atctttcctt acagtggttg ctgtgcacgg
    10381 aatttttgac ttggctctct tctggattca gtcaggcttt attttcttgc tagttatgtg
    10441 cagtattcca ttggagcatc gaatgttggt atcggacatg acggattaag ttttataagt
    10501 ttgaaatctt ctaccttggg taggagattt ttttatacga tgggcatgtc gtgcatctga
    10561 ggtgtaagtc ctctgtaggg atccactacc ggtgaataca atagcgctcc ccaagcctga
    10621 ctatcgtgag gtagcggatt aaaatggtct ggggatagat cgttttaagt ctgacgcagg
    10681 aaataagaat tgtcagagaa agcaatagtg aaatcgtagg ctatgaatag aaacgtgata
    10741 gcgaggagca tatagtggat aaggtagcga gaaattttaa agtataaaag atagtcttaa
    10801 tctatatatg taaatcacaa aagtaattga attcggaata aggttggtgt gaaaagacat
    10861 agtaaactga atcttgaata ctagaatgat acttctacaa tattgttata atttaatttg
    10921 aattccaaaa tcacattgtt ccgtccgtat ttcattttac tgtatgtctt cctaaactcc
    10981 aaagtttctg cgtcaaattt cctattttca ctgtagtctt tgacacttcg aacgacaatt
    11041 tgaatcatat attcaaaaaa aaatgaaaaa tttgtgccaa caagcctaaa tattctgaaa
    11101 atttgtttga tttttaatgg ataatgtgat ataatggttg tcaatctata attcacataa
    11161 acagaggagt agaaaatgaa aaaaaatcgt gtatttgcta cagcaggtct tgttttatta
    11221 gcagcaggtg tacttgcagc atgcagttct tcaaaatcat ctgattcatc agcccctaaa
    11281 gcttatggct atgtttatac agcagaccca gaaaccttgg actacctgat ttcaagtaaa
    11341 aatagtacaa cagtagtgac ttcaaatggg attgatggtt tattcactaa cgataattac
    11401 ggtaatcttg ctcctgcagt tgcagaggat tgggaagtct ctaaggatgg tttgacctac
    11461 acttataaga ttcgtaaagg ggttaaatgg tttacctctg atggagaaga atatgcagag
    11521 gtgacggcta aagatttcgt gaacggttta aaacacgcag cagataaaaa atcagaagct
    11581 atgtatttag ctgaaaattc ggttaaaggc ttggcagatt atctatcagg aacttcaaca
    11641 gatttttcaa cagttggtgt caaggcggtt gatgattata cgttacaata cactttgaac
    11701 cagcctgaac cgttctggaa ctctaagttg acctattcta ttttctggcc tctgaatgaa
    11761 gaattcgaaa catcaaaagg aagcgatttt gctaaaccaa cagatccgac atccttgctt
    11821 tataatggtc cattcttgtt gaaagggttg actgcaaaat cttctgtaga gtttgtaaaa
    11881 aatgagcaat attgggataa agaaaatgtc cacctagata ctatcaatct agcttactat
    11941 gatggatcag atcaggagtc gctagagcgt aacttcacta gtggagctta tagttatgcc
    12001 cgtctttacc ctaccagctc caactattct aaggttgcag aagaatacaa ggacaatatc
    12061 tattacacac aatcaggctc tgggattgct ggtctgggtg tgaatattga tcgccaaagt
    12121 tacaactata cttctaaaac tacagattca gagaaagtag ctactaagaa ggcattgctt
    12181 aacaaagatt tccgtcaagc cttgaatttt gctcttgatc gctcagctta ctcagctcaa
    12241 atcaatggta aagatggagc agctttagca gttcgtaatt tatttgtaaa accagacttt
    12301 gtttcagctg gtgagaagac ctttggtgat ttagtcgctg ctcaacttcc tgcttatggt
    12361 gatgagtgga aaggtgtgaa tttagctgat gggcaggatg gtttattcaa tgttgacaag
    12421 gccaaggcag agtttgcgaa agctaagaaa gctttagaag cagacggcgt tcagtttcct
    12481 attcatctgg acgttccagt agaccaagca tcaaaaaact acatatctcg tattcagtcc
    12541 tttaaacaat ctgtagaaac agttcttggt gttgaaaatg tcgttgttga tattcaacaa
    12601 atgacaagtg atgaattcct taatattact tactatgctg ccaatgcttc atctgaggat
    12661 tgggatgtat caggaggagt ttcatggggt ccagactatc aagacccatc tacttacctg
    12721 gatattttaa aaacaactag cagtgaaact acaaaaacat atttaggatt tgataatcca
    12781 aatagccctt cagtagttca agttggtttg aaagaatacg ataaattagt tgatgaagct
    12841 gccagagaga caagcgactt gaatgtccgt tatgaaaaat atgcagcggc tcaagcatgg
    12901 ttgacagata gttcactctt tattcctgct atggcttctt ctggtgcagc accagtgctt
    12961 tcacgaattg ttccatttac tggagcttct gcgcaaacag gctctaaggg gtcagatgtt
    13021 tacttcaaat atttgaaatt acaagataaa gtggtgacta aggaagagta tgaaaaagct
    13081 cgtgaaaaat ggttgaaaga aaaagctgaa tcaaatgaga aagctcaaaa agaattggca
    13141 agtcatgtga agtaaataat ttctaataga actttctctc catgaggaga aggttctttt
    13201 gggattttta aaggaaataa tatgaaaaaa tatattttta tgcgtgtttt gcggtcattg
    13261 gtttcgattt tcttagtaac gactttgacc tacacgatta tctatacctt ggttcctcga
    13321 aaattgattt tcaagcagga tcctaactat aataaaattg cgacaacggc tgataaacgt
    13381 gataactatg aaaatactgt gtttgagcgt atgggctaca ttgagtatta cgatactaaa
    13441 gagttgcaag aaaaggcaag tagcatggat tcttctgtaa cagtagaagc aaatgcgacc
    13501 aataaagcta tttatgaaaa gtacatcaat caattaggtc atggttggac tttgggagaa
    13561 tttactgaaa gtggtcaatt ctatgctact cgtgaaattc caatttttga acgtgttttt
    13621 cacttctatg ctaacttgat tgacattgac catacaaata aaatccaaga ccctgaaaat
    13681 ccagacttga aacgctacct tcgttttgaa aatgatccag ctatcggatg gtcattggtc
    13741 ggttcaggaa ctaaacataa atatctcttg tactttaaca gtcagttccc atttgttcat
    13801 caaaactttg tgaacttgaa tttaggtgac tcttacccaa cctatgctaa tacaccagtt
    13861 cttcaggtta ttactcaagg tcaaggacaa accaaaactg cccaagttca gttcccaaca
    13921 ggtaagaaaa cgtcttctgt aaatatttac tcaagaacct acaagtcacc tagtcaggct
    13981 gactctcgtg aagtagctag ctatgggaaa gatgatcctt atacagcgac tgaaagtaat
    14041 taccaatatc catctatgat tgtcagctct gctattactg gtttgattgg tttggttctt
    14101 gcctatgctc ttgccgtgcc acttggttca gccatggctc gtttcaagaa cacttggatt
    14161 gatagcctct caacagggac tttgaccttc ttgcttgctc ttccaacgat tgccttggtt
    14221 tacatcgttc gattgattgg atcatctatt gcccttccag attcattccc tatcttggga
    14281 gctggagatt ggcgttctta cgttttacca gcagtcatcc ttggtttgtt gggtgctcct
    14341 gttacagcca tttggattcg tcgttacatg attgacttgc aatctcaaga ctttgttcgt
    14401 ttcgctcgtg caaaaggttt gtctgaaaaa gaaatttcaa acaaacacat ctttaaaaat
    14461 gccatggttc cgctggtttc aggaattcct ggtgccatta ttggggttat cggtggtgca
    14521 acccttactg aaacagtctt cgccttccca ggtatgggta aaatgttgat tgactctgta
    14581 aaagcatcta ataactctat ggtcgttggt cttgtcttca tctttacatg tatttctatc
    14641 ttctcacgtc ttttgggaga tatttggatg actattattg acccacgtat taaattgact
    14701 gagaaaggag gcaaataatg tctacaatcg ataaagaaaa atttcagttt gtaaaacgtg
    14761 acgattttgc ctctgaaact attgatgcgc cagcatattc ttactggaaa tcagtgttta
    14821 aacaatttat gaagaaaaaa tcaactgtag tcatgttggg aatcttggta gccatcattt
    14881 tgataagttt catctaccca atgttttcta agtttgattt caatgatgtc agcaaggtaa
    14941 acgactttag tgttcgttat atcaagccaa atgcggagca ttggttcggt actgacagta
    15001 acggtaaatc gctctttgac ggtgtctggt tcggagctcg taactccatc ctcatttctg
    15061 tgattgcgac agtgattaac ttggttatcg gtgtttttgt cggtggtatt tggggtattt
    15121 caaaatcagt tgaccgtgtc atgatggaag tttacaacgt catctcaaac atcccacctc
    15181 ttttgattgt tattgtcttg acttactcaa tcggagctgg attctggaat ctgatttttg
    15241 ccatgagcgt aacaacatgg attggtattg ccttcatgat ccgtgtgcaa atcttgcgct
    15301 atcgtgactt ggaatacaac ttggcgtcac gtactttggg aacaccaacc ttgaagattg
    15361 ttgccaaaaa tatcatgcct caattggtat ctgttattgt gacaaccatg actcaaatgc
    15421 ttccaagctt tatctcatac gaagccttct tgtctttctt cggtcttgga ttaccgatta
    15481 cagtgccaag tttgggtcgt ttgatttcgg attattcaca aaacgtaaca accaatgctt
    15541 acttgttctg gattccattg acaacccttg tcttggtatc cttgtccctt ttcgtagttg
    15601 gtcaaaactt agcggatgct agtgatccac gtacacatag ataggagtag aaatgacaaa
    15661 agaaaaaaat gtaattttga ctgctcgcga tattgtcgtg gaatttgacg ttcgtgacaa
    15721 agtattgaca gccattcgcg gcgtttccct tgaactagtt gaaggagaag tattagcctt
    15781 ggtaggtgag tcaggatcag gtaaatctgt tttgacaaag accttcacag gtatgctcga
    15841 agaaaatggt cgtattgccc aaggtagtat tgactaccgt ggtcaggact tgacagcttt
    15901 atcttctcac aaggattggg aacaaattcg tggtgctaag attgcgacta tcttccagga
    15961 cccaatgact agtttggacc ccattaaaac aattggtagt cagattacag aagttattgt
    16021 aaaacaccaa ggaaaaacag ctaaagaagc gaaagaattg gccattgact acatgaataa
    16081 ggttggcatt ccagacgcag atagacgttt taatgaatac ccattccaat attctggagg
    16141 aatgcgtcaa cgtatcgtta ttgcgattgc ccttgcctgc cgacctgatg tcttgatctg
    16201 tgatgagcca acaactgcct tggatgtaac tattcaagct cagattattg atttgctaaa
    16261 atctttacaa aacgagtatc atttcacaac aatctttatt acccacgacc ttggtgtggt
    16321 ggcaagtatt gcggataagg tagcggttat gtatgcagga gaaatcgttg agtatggaac
    16381 ggttgaggaa gtcttctatg accctcgcca tccatataca tggagtctct tgtctagctt
    16441 gcctcagctt gctgatgata aaggggatct ttactcaatc ccaggaacac ctccgtcact
    16501 ttatactgac ctgaaagggg atgcttttgc cttgcgttct gactacgcaa tgcagattga
    16561 cttcgaacaa aaagctcctc aattctcagt atcagagaca cattgggcta aaacttggct
    16621 tcttcatgag gatgctccaa aagtagaaaa accagctgtg attgcaaatc tccatgataa
    16681 gatccgtgaa aaaatgggat ttgcccatct ggctgactag gaggaaggaa atgtctgaaa
    16741 aattagtaga aatcaaagat ttagaaattt ccttcggtga aggaagtaag aagtttgtcg
    16801 cggttaaaaa tgctaacttc tttatcaaca agggagaaac tttctcgctt gtaggtgagt
    16861 ccggtagtgg gaaaacaact attggtcgtg ctatcatcgg tctaaatgat acaagtaatg
    16921 gagatatcat ttttgatggt caaaagatta atggtaagaa atcgcgtgaa caagctgcgg
    16981 aattgattcg tcgaatccag atgattttcc aagaccctgc cgcaagtttg aatgaacgtg
    17041 cgactgttga ttatattatt tctgaaggtc tttacaatca ccgtttattt aaggatgaag
    17101 aagaacgtaa agagaaagtt caaaatatta tccgtgaagt aggtcttctt gctgagcact
    17161 tgactcgtta ccctcatgaa ttctcaggcg gtcaacgtca acgtatcggt attgcccgtg
    17221 ccttggtcat gcaaccagac tttgttattg cagatgagcc aatttcagcc ttggacgttt
    17281 ctgtacgtgc ccaagtcttg aacttgctca aaaaattcca aaaagagctc ggcctgacct
    17341 atctcttcat cgcccatgac ttgtcggttg ttcgctttat ttcagatcgt atcgcagtta
    17401 tttacaaggg tgttattgta gaggttgcag aaacagaaga attgtttaac aatccaattc
    17461 acccatatac tcaagccttg ctttcagcgg taccaatccc agatccaatc ttggaacgta
    17521 agaaggtctt gaaggtttac gacccaagtc aacacgacta tgagactgat aagccgtcta
    17581 tggtagaaat ccgtccaggt cactatgttt gggcgaacca aaccgaattg gcacgttatc
    17641 aaaaaggact aaactagtaa tggttttata atttccatgt caatttt
//
LOCUS       DBEROT010000044        15506 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.44, whole genome shotgun sequence.
ACCESSION   DBEROT010000044 DBEROT010000000
VERSION     DBEROT010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.44"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            164..1927
                     /gene="aspS"
                     /locus_tag="ACL8CG_001772"
     CDS             164..1927
                     /gene="aspS"
                     /locus_tag="ACL8CG_001772"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGS1344325.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITESLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVRGVDFKVFSEAPAVKAIVVTGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1905..2846
                     /locus_tag="ACL8CG_001773"
     CDS             1905..2846
                     /locus_tag="ACL8CG_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS1344326.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLTFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(2882..3130)
                     /locus_tag="ACL8CG_001774"
     CDS             complement(2882..3130)
                     /locus_tag="ACL8CG_001774"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344327.1"
                     /translation="MKIKVQTRKLATGCSKHCFEVVDRTDEVSSKHGFEVVDETDGVS
                     SKHGFEVVDETDEVSSKHGFEVADRTDEVSNIHTVRRR"
     gene            complement(3272..4258)
                     /locus_tag="ACL8CG_001775"
     CDS             complement(3272..4258)
                     /locus_tag="ACL8CG_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1344328.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4268..5068)
                     /locus_tag="ACL8CG_001776"
     CDS             complement(4268..5068)
                     /locus_tag="ACL8CG_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGS1344329.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5329..6171)
                     /locus_tag="ACL8CG_001777"
     CDS             complement(5329..6171)
                     /locus_tag="ACL8CG_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGS1344330.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6173..7465)
                     /locus_tag="ACL8CG_001778"
     CDS             complement(6173..7465)
                     /locus_tag="ACL8CG_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGS1344331.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7576..8847)
                     /locus_tag="ACL8CG_001779"
     CDS             complement(7576..8847)
                     /locus_tag="ACL8CG_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1344332.1"
                     /translation="MSSKFMKSAAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9382..10914
                     /gene="malQ"
                     /locus_tag="ACL8CG_001780"
                     /pseudo
     CDS             9382..10914
                     /gene="malQ"
                     /locus_tag="ACL8CG_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            10940..13198
                     /gene="glgP"
                     /locus_tag="ACL8CG_001781"
     CDS             10940..13198
                     /gene="glgP"
                     /locus_tag="ACL8CG_001781"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGS1344333.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14243..14815)
                     /locus_tag="ACL8CG_001782"
     CDS             complement(14243..14815)
                     /locus_tag="ACL8CG_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344334.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNRRINF"
     gene            14892..15098
                     /locus_tag="ACL8CG_001783"
     CDS             14892..15098
                     /locus_tag="ACL8CG_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344335.1"
                     /translation="MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFSFRG
                     SVWGLVLALYHLLFIDKFVISNRK"
BASE COUNT         4611 a         2911 c         3302 g         4682 t
ORIGIN      
        1 aaggcgacgc tgacgtggct tgaagagatt ttcgaagagt attagcgcta atttttaggg
       61 ctttcacctg acttttaaag actggcaaac ttttctgatg attttcatga agagcctgcg
      121 cttttatggt aaaatagtaa cagaataaaa gaggagagaa ataatgaaac gtagtatgta
      181 tgctggtcgt gttcgtgagg aacacatcgg acaagaaata accttgaaag gatgggttgg
      241 ccgtcgtcgt gaccttggtg gtttgatctt tatcgatctt cgtgaccgtg aaggaatcat
      301 gcagttggtt atcaaccctg aaaaagtatc tgcagaggtt atggcaacag ctgaaagcct
      361 tcgtagcgaa tttgttattg aggtgactgg tcaggtcgct gcgcgtgagc aagccaatga
      421 taagttgcca actggtgcgg ttgagttaaa cgtgacagct cttattgtgc ttaacacagc
      481 taagacaaca ccatttgaga ttaaggatgg cattgaggca aatgacgata cacgtttgcg
      541 ttaccgttac cttgaccttc gtcgtccaga aatgttggaa aatcttaaac ttcgtgccaa
      601 ggtgacccac tctatccgca actacttgga tgagttggag tttatcgacg tggagacacc
      661 attcctttct aagtcaacgc ctgaaggggc gcgtgattat ttagtgccgt ctcgtgttaa
      721 taaggggcat ttttacgctc ttcctcaaag tccacaaatc acgaaacagc tcttgatgaa
      781 tgctggtttt gaccgttact accaaatcgt taaatgtttc cgtgacgagg acttgcgtgg
      841 agaccgccag cctgaattta ctcaggtcga cttggaaacg tccttcctta ctgagcaaga
      901 aatccaagat attacagaaa gcttgatcgc gcgcgtgatg aaggaaacaa aaggcatcga
      961 agtaacgcta ccattccctc gtatgaaata cgatgatgct atggctcttt acggttctga
     1021 caagccagat actcgttttg acatgttgct tcaggacttg acagaagtgg tccgaggtgt
     1081 agactttaaa gtcttttcag aagcacctgc tgtaaaagcg attgtggtca caggagctgc
     1141 ggacaactat tcacgtaaag acatcgacaa gatgacggaa gtagccaaac agtatggtgc
     1201 caaaggtctt gcttgggtca aggtggttga tggagaatta aacggaccag ttgccaagtt
     1261 cttgactggt atccaagaag aattgacaac agcgcttgtt cttgaagata aggacttggt
     1321 tctctttgtg gcggatacgc ttgaagtggc taatgcaaca ctgggtgccc ttcgtggacg
     1381 tattgctaaa gagcttggct tgattgataa tgataagttc aacttccttt gggtggttga
     1441 ctggccgatg tttgaatggt ctgaagaaga aggccgctac atgagcgccc accatccttt
     1501 cacacttcca caggaagaga ctgctcatga attagaaggt gatttggcta aggttcgtgc
     1561 cattgcttac gatatcgtct tgaacggtta tgagcttggt ggtggtagcc ttcgtatcaa
     1621 ccaaaaagac cttcaagaac gcatgttcaa ggctcttggt ttctcaactg aagaagccaa
     1681 tgaccagttt ggtttccttc ttgaagccat ggactatggt ttcccaccac acggtggttt
     1741 ggctatcggg cttgaccgtt ttgtcatgtt gcttgctgga gaagaaaata tccgtgaagt
     1801 cattgccttt cctaagaaca acaaggcaac tgacccaatg acacaagctc catcaacagt
     1861 cgctctcaaa caactagagg aactcagctt acaagtagaa gaagatgaaa caaacaaaac
     1921 gaattaagcg gtggcgctat tatctgcgcc gctttgctta tcagataaaa attttacgtg
     1981 tcttacaaag tatctctcga gaaaagtatg atgagaagat ttcggcctct ctggtctatg
     2041 gttttttatc agcagtagca gttaatttct ttttccaacc agggcatgtg tattcgagtg
     2101 gtgcaacagg tctggcacag attatctctg ccttgagtaa tcactggttt ggttttcata
     2161 ttccgatttc gctaaccttc tacgccatta acttcccttt gatggtctta gcttggtatc
     2221 agattggcca taagttcacc gtctttacct ttatcacggt atctatgagt tccttcttta
     2281 tccagtttgt ccctgtggca accttgacgg aggatcccat tatcaatgcc ctttttgggg
     2341 gtgttgttat gggtttgggg attggttttg ctcttcgaaa caatatctcc agtggtggga
     2401 cggatatcgt cagcctgact attcgcaaga aaacgggtaa gaatgttggt agtatttctt
     2461 tcttggtaaa tggaactatc atgctgatag caggtttgac ctttggttgg aaatacgctc
     2521 tttattctat gattaccatc tttgtctcta gccgtgtgac agacgcagtc tttactaagc
     2581 aaaagcgtat gcaggccatg attgtgacaa atcatccaga gaaggtaatt gaaaaaatcc
     2641 ataaaaaatt gcaccgcgga gcaaccatga tccatgatgc agaaggaacc tataatcacg
     2701 agagaaaggc agttttaatc actgtcatta cacgtgcaga gtttaatgaa tttaaacaga
     2761 ttatgacaca agtggatcca agctcctttg tctctgtctc ggaaaatgtt catattctag
     2821 gaagatttgt tgagatagat aattagtgat taatactctt cgaaaatctc ttcaaaccac
     2881 gtcagcgtcg ccttaccgta tgtatgttac tgacttcgtc agttctatct gcaacctcaa
     2941 aaccatgttt tgagctgact tcgtcagttt catctacaac ctcaaaacca tgttttgagc
     3001 tgactccgtc agtttcatct acaacctcaa aaccatgttt tgagctgact tcgtcagttc
     3061 tatccacaac ctcaaaacag tgttttgagc aacctgtggc tagcttccta gtttgcactt
     3121 tgattttcat tgagtataaa aagatcttgg gtaacaactc aatttcagta gaaaaggaag
     3181 taaatcttcc cacaataaaa cgcatagtat caagtttttt caatacctga tagtatgcgt
     3241 ttttgctttt aacgactttt tgcccagtct cttatttttc gataattttg tgggcgatca
     3301 attgacggta acaaatttgt ttattgtttt tattatcatt aataatctgg agaatagttt
     3361 caagggaaac acgaccaagc tctaaactat tgatatcgac ataggctgcc aagttgagct
     3421 tgggattaac cgagtcaaag ctgagaacag ggacatccag ctggtgtttg gcaatatagt
     3481 tacaaacacc ttcagctagg aggctatcgg ttgtgatgat agcatcaatt tgtggatcgt
     3541 gcttgaataa tcgcttgcta aatttatagc ccttttcttc cagaaactcg tcggcaaagt
     3601 agatgcgatt gttgtcagtg gtaagtttgt aatgtttaag cgcctgttca tagcctgtta
     3661 aacggtcttt ggtcacgaag agctttttac ttcctccgat aaaggcaatg cgtttgcagc
     3721 cttttttgat gaaatattca gtcgcatcaa aaccagcttg aacattgtcg ttgtcgacaa
     3781 gtgggatgaa aggagataga gatttaccta agataaggaa ggggaactgt tcttctgcga
     3841 cgagttttac gagagggtct tcttcttggg catagagaaa gattagccca tctacacgct
     3901 tgccgtagac catttgtgaa atagcgttga gacgctcctt ctcatctttc cctgttgcta
     3961 tctgaatggc atagtggttt tcagatgcga cttgagagat gccacgtaga accgatggaa
     4021 agaaaggatt ctggtagaag gcgtctgagt catcaggaag aactaatccg ataacctgag
     4081 tatagctgct taccaagcta cgagcgttga ggtttgggtg gtagttgagt tccttcatag
     4141 ctttgcgaac gcgttttttt gtttcgtcgc taatggttga tttattttga ataacacggg
     4201 ttacggttga aggcgaaaca ccagcagcct tggccacgtc tttaatcgta acgggcataa
     4261 aaatctccta tttatggtaa tttggatcac ggaaatgtgt tttataaaag atagtgacca
     4321 gatacagaac aaaaagaata ttttgtacag taatcagggt tgtcatattt tggccaaata
     4381 atcccaaaat aagtgtaatc agagtcggca atcctaaaca gttcaagata aagtgatagc
     4441 actctttaaa ggttctaaat gaaaagaggc gtgatttctt agtgatataa aggagaagac
     4501 tagctcctag agagacgata aagaaattca aaccaaagag gaagctcgca ccgagaacta
     4561 ggaagaggct gatatagaca cgattttgtt ggtaccagtc tttagaaatt gcttgggtca
     4621 agctgtcttt gcttttgaaa ctctcagtct gaatggctcg gtaagagatg cgggtcagtt
     4681 ccttgctttc cttgctgatg actagctcat ttgtatcgaa atgcagttgc aagtccttag
     4741 gtaattcctt gatttgactt ggaccaatca caacagaagg ggcttgacta gctgttccag
     4801 tataagttaa tgtgccatcg acaattgtag catgttcaga gagatcctgg acaacctcat
     4861 ttgtcagagg ttcatagaca ttatcgataa aagtttctag cggataggtc tcctgggagc
     4921 tgttttggat agcaatgggt accatagaca agctgataag gaagatactg gtaaagagaa
     4981 gttgaaacca gttgagctcg aaacgtttgg acaggggctt acgaaacccc caaatacttg
     5041 aaaaatagga aaatggatat ggaagcatag gtatctttct aaaaggtgtt ttctatatga
     5101 gtattattat atagagaaat gcgctttatt tcaagtctag ggggtaaatt gcttgctaca
     5161 aggatattat ttacagtgac aatcgctaat agtcaatgaa aatcaaagtg caaaccagga
     5221 agctagctgc aggttgctca aagcacaact ttgaggttgg agataaagct gacgtggctt
     5281 gaagagattt tcgaagagta taaaatgaaa aagggtggcg gggataaatt atcccttgtc
     5341 gccaccactt gtaagtcctg aaacaaagtt cttttgtagg aagaagaaga gaatacagat
     5401 tggaagggcg atgaggatag cacctgctga gaagtaggca atcttcaagt ttttcgcatt
     5461 gttaacgaag gtttggagac ctacggcaac agtaaagtat tctttctcac gaagcaagaa
     5521 actagagagg atgtagtccc cgaaaggtcc catgaaggcc cagagagctt gtacggcaac
     5581 cattgggcga acaagtggta gaacaatttg ccagaagcgg cggaagtgtc ctgcaccgtc
     5641 tagttttgca gattcgtcta aagacattgg cactgtatcg aagtagcctt tcatgagcca
     5701 agcattcatc gggataccac caccaacgta gaggaagatg aggaaccagt tgtggttaag
     5761 ggcgttcaac ataagcgcca taacgaagaa ggctgtcaaa gcggccatag ttggcaccat
     5821 ttggatgatc aagaagaaga ccaaactttg tttacgagcc aagaagttgt aacggctgta
     5881 agcataacca gcaagtacga tgatacttgt ttgaacagcc atggtaatta aggcgataat
     5941 caaagtgttg aggtaccaag taccgtacaa ggtttcagtg aagaggcctt taaagttatc
     6001 aaaattgagg tcgatattag tatctagttt aaaggctgag acgttacctg ctttaaaggc
     6061 tgacatgatg gtaatcaaca gtggatagat aattacaatt gatagaccaa tcaggtaaag
     6121 gtaagtaagg ctttgagtca gtctacgttt gagtttaatt gagttattca tcttagacgt
     6181 cctccatatc aaatgcgtgt agtttcttga atgcgatcat agagattgag atgacaatga
     6241 tagagataat caaggtaaca gctgccgcca ttgagtattg aggagatgta cctgttgtca
     6301 aacggtagat ccatgagatc aagatatcgg ttgaaccagc tccacctccg acactaccag
     6361 gtcctccacc attgaagagg tacatgatag agaagttgtt aaagttgaag gtgtattggc
     6421 taatcaaagt aggtgccgca acagccaaaa tcattgggaa agtgatgttg cggaattttt
     6481 gccaagcgtt ggcaccgtca atataagctg cttcgtaaag gtcgttagga atagattgca
     6541 agatacccaa agtcaaaacg tagatgtatg ggaatccgag ccaaccttgc atcataatca
     6601 aggcaatctt agtccaagtt gggtctgttt tccaaggaat aagagctcca tcaaggaaag
     6661 gaaggaattt agccaagatt ggcaatactt gagtgttgat agcaccgaca ctatcgttaa
     6721 acatgtttga gaatgtcaag atagtgatga aggctgggac agcccaagga agaaggaaaa
     6781 taacaccaaa gatacgtttt cctttgataa atggttggtt ggcaatgata gctgtgaaga
     6841 taccaattac gatttgtaaa gtagaagctg ccaaagccca aatgatagtc caagaaagaa
     6901 cagaaccaaa ggcagaacgg aaggtactca agctccaaat gtttgtaaag ttggtcaaac
     6961 caacccagtc caacaacttg tttggtggca agtgttggaa gtcgtagttg gtaaaggcga
     7021 tcatcaaggt tacgataact gggaagataa tcgcgaaggt catggcaaca taagatggaa
     7081 tgatcaagag gtaagggaag ccattttcat aaatcccttt gatcatgtct ttgagtgtgc
     7141 gtggaactgg aattccattg ttaatgcgtt ttgcaatcgt atgtgcatct ttgatatttg
     7201 agaaataaaa gagtacataa acgattacaa agattagatg gaaggcacca cgaatcagca
     7261 taaagaggga attatcacga cctggtttgt caccaagagt gatgaggttg ctcaattcag
     7321 gggttgcaag tgctaggaag taaaggacaa atacgatggt tacaccaagg aagataaaac
     7381 ctttggcttt ttgtttattg taaatctgtc ctaacccagg aatgatagac agcagggctg
     7441 ctttactagg ttgttgcttt tccatattaa ctcctttcat aggatactac ttttttataa
     7501 gaaagctaaa ttatttgtgt ctctattgat aaattcaaag ggggatttga tttccacccc
     7561 ccttgaacaa attttttatt caccaaattt ttgtttgatt gtttctttga tcaatgttac
     7621 agcatcgtta gcagctgttt tagcatcttt ttgaccactt acagcatcaa agagcatatt
     7681 tttcgctgga tcccaaactg cagacatttg agagatgttt ggcagtggtt gagtgttctt
     7741 gaactgtttg ataacagctg ttgtcaactc atcgttttta ccttcagcgt atgaacgagc
     7801 ctcagtatta gctgggattt cgttagtctt atcatataat actttttgtt gttcagttgc
     7861 aacaaggaag tctacaaatt tttgagaagc ttcaaggttc ttaacggctt gaggaatgac
     7921 ccaagcttta ccaccaccga atgcagcata ttcttttcca tttggaagag ttgggatagt
     7981 tgcaactccg tagtttactt tagcatcttt aaaggcttga gctttccaag gtccgtcgat
     8041 gatagcagct gttttacctt cttggaattg agtttggatt aagtttccag caccttctgt
     8101 atcttgcata cctttaggcc atttttcgta ccaagattta gcgtagttga tacctacgat
     8161 agaaccgtcg tttgcaagac cgatgtcttt agcgtcttta ccgttttggc caaagacgta
     8221 agcaccgtta ccggcaagaa gtccatatgt atagtagaag tttgtccagt cagctaggaa
     8281 ggcagtagtt ttaccatctt caccagcgaa tgcgtatttg ctatctttag caaggttttc
     8341 caagtcagca aatgtttttg gagcatcttt caccaagtct ttgttgtagt acataacaag
     8401 tgactcgata acggcaggag caccgtaaac tttaccatta gcagctgtta caagagattt
     8461 agttgtgtcg tctgttttag caccatcgct caatttcact tctgaaagtt gtccgtcaga
     8521 accaaggcta cctacacggt cgtatggagc catcataaca tcagggacat taccagattg
     8581 gttgtcaaga gaaagtttat caagacctcc tagagcatca ccagttttaa gagtgacttt
     8641 tactccagct tctttttcat aagctttagc aacctcttca atatagctct tatatccctc
     8701 gtctacatat acagtgagtt ctttgacttc agatgaacca gaatcagcag gcttatcagc
     8761 agttttgctt ccgcaagcta ccaaaagcaa gctagcaagt gtaacagttc caagcaccgc
     8821 agcgctcttc ataaatttag atgacatagt gtattcctcc caaagaatag caagttttat
     8881 tgataaggaa acgcaaacgt tttcctttat gagcttagta tagcacaaat agaaaacggt
     8941 tgcaagtatt ttttgtaaaa attttaaaaa atttttaagc ttgatttgat agcataattt
     9001 tgcattttaa tagaagaaaa gtatgaaata gataagaata cagtattttt aataaaaata
     9061 tatggaatat gtctaaagag ggaaaccagg aggggctacc tccctggttc taatccctat
     9121 ctattttcta tggacgtttg tgctttgtta catataaatt caagctccct aaggaggttt
     9181 tgtactttgt agactgtctc gtgagagtca aaccttagga ttagatagtt ttaagttatc
     9241 tttgctaaaa tgagttagtc tccttaaaaa taatcaaaaa agttttttaa aaacgcttgc
     9301 aattatgctt gaaaaggagt atacttataa gtaacgcaaa cgtttgcgtc tgcaaaatac
     9361 gcaacgttcc attattttaa cacacgaggt gctattatga aaaaacgtca aagtggtgtg
     9421 ttgatgcaca tctcttctct tccaggagct tacggaatcg gatcatttgg tcaaagtgct
     9481 tacgacttcg ttgatttctt ggtccgtaca aaacaacgtt actggcaaat ccttccatta
     9541 ggagcaacta gttacgggga ttctccttac caatctttct cagccttcgc aggaaacact
     9601 cattttatcg atttagatat cttggtggag caaggtttgt tggaagcaag tgaccttgaa
     9661 ggagttgact ttggtagcga tgcgtctgaa gttgactatg ctaaaatcta ctatgcacgt
     9721 cgtcctcttt tagaaaaagc ggtgaaacgt ttctttgaag tcggagatgt taaagatttt
     9781 gagaaatttg ctcaagacaa ccaatcatgg cttgagctct ttgctgagta tatggctatc
     9841 aaagagtatt ttgacaatct tgcttggact gaatggccag atgcagatgc tcgtgctcgt
     9901 aaagcttcag cacttgaaag ctatcgtgag caattggcag acaagttggt ttaccaccgt
     9961 gtgactcaat acttcttctt ccaacaatgg ttgaaattga aagcttacgc taacgacaac
    10021 cacatcgaaa tcgttgggga catgccaatc tacgtagcgg aagattcaag tgatatgtgg
    10081 gcaaatccac atctcttcaa aacagatgtc aatggtaagg ctacttgtat cgcaggatgc
    10141 ccaccagatg agttttctgt aactggtcag ctttggggta acccaatcta tgactgggaa
    10201 gcaatggaca aagacggcta caaatggtgg attgaacgct tgcgtgaaag cttcaaaatc
    10261 tacgatatcg ttcgtatcga ccacttccgt ggcttcgaat cttactggga aatccctgct
    10321 ggttccgata cagcagcacc tggtgagtgg gtgaaaggtc caggctacaa gctttttgca
    10381 gccgttaagg aagaacttgg tgagctaaac atcatcgcag aagaccttgg cttcatgaca
    10441 gatgaagtga tcgaattgcg tgaacgtact ggcttcccag gaatgaagat tcttcaattt
    10501 gccttcaacc cagaagacga aagcattgat agcccacact tggcacctgc taactcagtt
    10561 atgtacacag gaacacacga taacaatacg gttcttggtt ggtaccgtaa cgagattgat
    10621 gatgcgactc gtgagtacat ggctcgttac acgaaccgta aagaatacga aacagtggta
    10681 cacgctatgc ttcgtacagt attttcatca gttagcttta tggcaattgc aactatgcaa
    10741 gatttactag aattggatga ggcagctcgt atgaacttcc catctaccct tggtggaaac
    10801 tggtcttggc gtatgactga agatcaattg acaccagctg tcgaggaagg tttgcttgac
    10861 ttgacaacaa tttatcgccg aattaatgaa aatttggtag atttaaagaa ataagacaat
    10921 aatcaggaga caactaaaca tgttatcact acaagaattt gtacaaaatc gttacaataa
    10981 aaccattgca gaatgtagca atgaagagct ttaccttgct cttcttaact acagcaagct
    11041 tgcaagcagc caaaaaccag tcaacactgg taagaaaaaa gtttactaca tctcagctga
    11101 gttcttgatt ggtaaactct tgtcaaacaa cttgattaac cttggtcttt acgacgatgt
    11161 taaaaaagaa cttgcagctg caggtaaaga cttgatcgaa gttgaagaag ttgaattgga
    11221 accatctctt ggtaatggtg gtttgggacg tttggctgcc tgctttatcg actcaattgc
    11281 tactcttggt ttgaatggtg acggtgttgg tcttaactac cactttggtc ttttccaaca
    11341 agttcttaaa aacaaccaac aagaaacaat tccaaatgca tggttgacag agcaaaactg
    11401 gttggttcgc tcaagccgta gctaccaagt accatttgca gactttactt tgacatcaac
    11461 tctttacgat attgatgtta ctggttatga aacagcgact aaaaaccgct tgcgtttgtt
    11521 tgacttggat tcagttgatt cttctattat taaagatggt atcaactttg acaagacaga
    11581 tatcgctcgc aacttaactc tcttccttta cccagatgat agtgaccgtc aaggtgaatt
    11641 gctccgtatc ttccaacaat acttcatggt ttcaaacggt gcgcaattga tcatcgacga
    11701 agcaatcgaa aaaggaagca acttgcatga ccttgctgac tacgcagttg tccaaatcaa
    11761 cgatactcac ccatcaatgg tgattcctga attgattcgt cttttgactg cacgtggtat
    11821 cgagcttgac gaagcaatct caattgttcg tagcatgact gcctacacta accacacaat
    11881 ccttgctgaa gcgcttgaaa aatggcctct tgaattcttg caagaagtgg ttcctcactt
    11941 ggtaccaatc atcgaagaat tggaccgtcg tgtgaaggca gagtacaaag atccagctgt
    12001 tcaaatcatc gatgagagcg gacgtgttca catggctcac atggatatcc actacggata
    12061 cagtgttaac ggggttgcag cacttcatac tgaaatcttg aaaaattctg agttgaaagc
    12121 cttctacgac ctttacccag aaaagttcaa caacaaaaca aacggtatca ctttccgtcg
    12181 ttggcttatg catgctaacc caagattgtc tcactacttg gatgagattc ttggagatgg
    12241 ttggcaccat gaagcagatg agcttgaaaa acttttgtct tatgaagaca aagcagctgt
    12301 caaagaaaaa ttggaaagca tcaaggctca caacaaacgt aaattggctc gtcacttgaa
    12361 agaacaccaa ggtgtggaaa tcaatccaaa ttctatcttt gatatccaaa tcaaacgtct
    12421 tcacgagtac aaacgccaac aaatgaacgc tttgtacgta atccacaaat accttgacat
    12481 caaagctggt aacatccctg ctcgtccaat cacaatcttc tttggtggta aagcagctcc
    12541 agcctacaca atcgctcaag acattatcca tttaatcctt tgcatgtcag aagttattgc
    12601 taacgatcca gcagtagctc cacacttgca agtagttatg gttgaaaact acaacgttac
    12661 tgcagcaagt ttccttatcc cagcatgtga tatctcagaa caaatctcac ttgcttctaa
    12721 agaagcttca ggtactggta acatgaaatt catgttgaac ggagctttga ctcttggtac
    12781 tatggacgga gctaacgtgg aaatcgctga gttggttggt gacgaaaaca tctacatctt
    12841 tggtgaagat tcagaaactg ttatcgacct ttacgcaaaa gcagcatata aatcaagcga
    12901 attctacgct cgtgaagcta tcaaaccatt ggttgacttc attgttagcg atgcagttct
    12961 tgcagctgga aacaaagagc gcttggaacg tctttacaat gaattgatca acaaagactg
    13021 gttcatgact cttcttgact tggaagacta catcaaagtc aaagagcaaa tgcttgctga
    13081 ctacgaagac cgtgacgcat ggttggataa agtcatcgtt aacatttcta aagcaggatt
    13141 cttctcatct gaccgtacaa tcgctcagta taacgaagac atctggcact tgaactaata
    13201 ctcttcgaaa atctcttcaa accacgtcag ctttatctgc aacctcaaag cggtgctttg
    13261 agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaaa
    13321 tttatactaa tacattttgt aaaaaagcga gtttcgattg aaattcgctt ttttaaatgc
    13381 tgtggatttg ggtcaatctt gtctaaaaat agggaaatcc tagatacagt gaaggcttta
    13441 aatgctggtt tttactgtct ttagccttat attttttcgt agttggttac ctcatatctc
    13501 ttgtattcgc ttacataaag tattataata taattgtagg aaagaaggtg tttttatgat
    13561 atacacactt aaattggtgt tgtttattac ctttcttgta ataagcttgt tacctgataa
    13621 gatttttgga aaaaataaaa aaatttggaa aatagttttt gcaatattga cggcagtggc
    13681 agcattgtca tttatgtact aagttatttt aagaatgtag ggaaataaac cctacattct
    13741 ttttagtttt ttctgttttc taaattctat ttatccaagc gcttcaacat ttcttgcttc
    13801 ttcgcttcaa gttctgcacg cttttcttcg atttcggcat gttttttctc gagttcagaa
    13861 caacttgcat cattgctaaa ttcttttcgc catcaggaga tagggtgagt cgacatgtct
    13921 attactcacc caaagcagtc ctacaaagca ggaattttct gttacttttt tggaaatagt
    13981 aacgtttata cagctttgac acttcgtatc aaagcgccaa acacactccg agggatttac
    14041 agaaagcaga aaaggaatga tctggtataa gatcattcct tttctctctt tttctttaag
    14101 taattatata caatgtacga cgaagtcgtc attgcaatgc tgatccacca cctaaaggga
    14161 actttaaaca agattgataa gataaagaat ataaacaacg aaaatacgtt atacccaatt
    14221 aattttattg tatatctcat gattaaaagt taatccttct gttgttagga atggcatcat
    14281 ttttatccca taattgtgct aaataagtcc ccggtgataa taaattcata gcgaattcta
    14341 aagcaacatc atttacaaac caactaccta gatatctaga aattgctgaa cgaatagcac
    14401 tttttgctgc atgttttcct tttactttaa ttagatttgc aaggcctgca gtagttcctc
    14461 ctaatgctaa agctattgca gtatctaata gagcacccat ttgattaact gtaatacctt
    14521 gccaagctgc tctaaatgga gagtatgtag gtgggattgt ataatcgcct tgtaattgtc
    14581 ggttaattac ttctttgatc cattgttgtg agacgtctgg atgaaaagat tggatttcgt
    14641 ttgcaagtgt attgatttgt tcttctgtta gagaagtgac aggttgaagt tccatatttg
    14701 tttcaatttg tgatacttgt tcagaagcgt atacagctga aacacttgga atcgctgata
    14761 caattaacac aattgacgtc aaaaaaaccg aaataaattt cattaatttg ttcatgaact
    14821 tttctccttt ttatttgtat ctgcttacat tttatcatat actgttatta tagtcaaaaa
    14881 aatatgctat tatgttaaaa aaatattttt caaaatataa atggacggat ttattttgga
    14941 ttttatttgt tattttgacc tgcctctata ttggtaacca tgatttgttt actctcaatc
    15001 atcaagaatt ctcttttcgt ggtagcgttt ggggtctggt actggcctta tatcacttac
    15061 tattcattga taagtttgtt atatcgaatc gaaaataaag attagagcta tgcttgactg
    15121 gctactttta ggattgattt tggaggaaga ttttgtctct attatttatt attttaaatt
    15181 tatttatttt gtataagatc tattctttga ggcgggaaaa atcgaaatac ttgatttata
    15241 cggcctatat catatttggg gtaaatgtag tatatggtat tcaatggtta ttaaaagaac
    15301 tgatttcaac tatttcccct taatgtgtat ggaaactata acaaaacgca taagattaag
    15361 gtttgtgtac ctgttcttat acgtttttgt catattgaag attttcggta agttttctac
    15421 ttttgcgaag tctagtttat actcaatgaa aatcaaagag taaactagcc gtaggttgct
    15481 caaagtacag ctttgaggtt gcagat
//
LOCUS       DBEROT010000045        14832 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.45, whole genome shotgun sequence.
ACCESSION   DBEROT010000045 DBEROT010000000
VERSION     DBEROT010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14832
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.45"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(123..1745)
                     /gene="groL"
                     /locus_tag="ACL8CG_001784"
     CDS             complement(123..1745)
                     /gene="groL"
                     /locus_tag="ACL8CG_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGS1344336.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1761..2045)
                     /gene="groES"
                     /locus_tag="ACL8CG_001785"
     CDS             complement(1761..2045)
                     /gene="groES"
                     /locus_tag="ACL8CG_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGS1344337.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2201..2596)
                     /locus_tag="ACL8CG_001786"
     CDS             complement(2201..2596)
                     /locus_tag="ACL8CG_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGS1344338.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2674..3435)
                     /locus_tag="ACL8CG_001787"
     CDS             complement(2674..3435)
                     /locus_tag="ACL8CG_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1344339.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3477..4103)
                     /gene="ytpR"
                     /locus_tag="ACL8CG_001788"
     CDS             complement(3477..4103)
                     /gene="ytpR"
                     /locus_tag="ACL8CG_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGS1344340.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4119..4436)
                     /locus_tag="ACL8CG_001789"
     CDS             complement(4119..4436)
                     /locus_tag="ACL8CG_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGS1344341.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(4433..4732)
                     /locus_tag="ACL8CG_001790"
     CDS             complement(4433..4732)
                     /locus_tag="ACL8CG_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGS1344342.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(4930..5010)
                     /locus_tag="ACL8CG_001791"
     CDS             complement(4930..5010)
                     /locus_tag="ACL8CG_001791"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344343.1"
                     /translation="MASSSKMFRNTYTPDGYYVGNLGAWQ"
     gene            complement(5017..5208)
                     /locus_tag="ACL8CG_001792"
     CDS             complement(5017..5208)
                     /locus_tag="ACL8CG_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGS1344344.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5369..6043)
                     /locus_tag="ACL8CG_001793"
     CDS             complement(5369..6043)
                     /locus_tag="ACL8CG_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344345.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(6049..6495)
                     /locus_tag="ACL8CG_001794"
     CDS             complement(6049..6495)
                     /locus_tag="ACL8CG_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1344346.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6609..7112)
                     /locus_tag="ACL8CG_001795"
     CDS             complement(6609..7112)
                     /locus_tag="ACL8CG_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS1344347.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7109..7471)
                     /locus_tag="ACL8CG_001796"
     CDS             complement(7109..7471)
                     /locus_tag="ACL8CG_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGS1344348.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7537..8568)
                     /locus_tag="ACL8CG_001797"
     CDS             complement(7537..8568)
                     /locus_tag="ACL8CG_001797"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344349.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(8575..9396)
                     /locus_tag="ACL8CG_001798"
     CDS             complement(8575..9396)
                     /locus_tag="ACL8CG_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344350.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM"
     gene            complement(9412..9882)
                     /locus_tag="ACL8CG_001799"
     CDS             complement(9412..9882)
                     /locus_tag="ACL8CG_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS1344351.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(10006..10722)
                     /locus_tag="ACL8CG_001800"
     CDS             complement(10006..10722)
                     /locus_tag="ACL8CG_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1344352.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11603..13018)
                     /gene="ply"
                     /locus_tag="ACL8CG_001801"
     CDS             complement(11603..13018)
                     /gene="ply"
                     /locus_tag="ACL8CG_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGS1344353.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALMKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13029..13439)
                     /locus_tag="ACL8CG_001802"
     CDS             complement(13029..13439)
                     /locus_tag="ACL8CG_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344354.1"
                     /translation="MIKRGDVVVLYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDHLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(13432..14040)
                     /locus_tag="ACL8CG_001803"
     CDS             complement(13432..14040)
                     /locus_tag="ACL8CG_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344355.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14053..14511)
                     /locus_tag="ACL8CG_001804"
     CDS             complement(14053..14511)
                     /locus_tag="ACL8CG_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGS1344356.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14636..14746
                     /locus_tag="ACL8CG_001805"
                     /pseudo
     CDS             14636..14746
                     /locus_tag="ACL8CG_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         4309 a         3444 c         2688 g         4391 t
ORIGIN      
        1 aaatttgtcc tttctcgagc ttagctgact tcaacccact acagttgaca aagagcctat
       61 aaaaagaagg gttagtcatt ccctcctttt gtgtttttta taagttgttt tctatagaaa
      121 gcttacatca tcccgcccat catacttgga tccattgctg gagctggggc tactggttct
      181 ggtttattgg ctacgactgc ttctgttgtc aaaatcaagc tggctacaga tgctgcattt
      241 tgtagggctg aacgactcac tttaactgga tcaatgatac cttgatcaat catgttaacc
      301 cactcgccag ttgctgcgtt aaatcctata ccaagctcag catttttcaa acgatcgata
      361 acgatagatc cttcaaatcc tgcattgtga gcaatttgac gaacgggttc ttccaaagca
      421 cggagaacaa tattacgtcc tgttgcttca tctcctgtca attccaaggt agcaacagct
      481 ggaatcacat tggcaagagc tgttccaccg cctgcaacaa taccttcttc aacagctgca
      541 cgagtagcgt tgagggcatc ttcaatgcgg agtttcattt ctttcaactc agtttcagtt
      601 gcggctccga ccttaataac cgctacacca cctgacaatt tggccaagcg ttcttgcaat
      661 ttttcacggt caaattcaga agttgtagtt tcgatttgag acttgataac cgcaacacgg
      721 tgagaaatcg cttcaggatt tcctgcacct tctacaataa ccgtgctatc tttgtccacg
      781 gtcactctcg ctgcttgacc aagagcttca attgtcgcat ctttcaactc aagaccaagg
      841 tcttctgtga taactgttcc gcctgttaag atggcgatat cttcaagcat ggctttgcga
      901 cggtcaccaa aaccaggtgc cttgactgct actacgttga aggttccacg aatcttgttc
      961 aaaacaagag ttggaagagc ctcgccatcc acatcatccg caataatcaa gagtggacga
     1021 ttgctttgga gaatgctttc caaaagtggc aagatctctt ggatattgga aattttcttg
     1081 tctgtaatca aaatgtacgg attttcaagg tcagccacca ttttttcgct atctgtcacc
     1141 atgtactgtg aaaggtaacc acggtcaaac tgcattcctt ctacgacttc aagctctgtt
     1201 tccataccac gtgactcttc gatggtgatg acaccgtctt tgccaacttt ttccattgct
     1261 tcagagatgt actcaccaac tttttcagaa cgagaagata cggctgcaac ttgagcgata
     1321 gcttctttat tggcaacagg gatggcgttg tttttcaaag cttcaactgc tgcggcaact
     1381 gctgtttcaa tcccacgacg aataccgatt ggatttgcac ctgctgtgac gtttttgatt
     1441 ccttcacgga cgatagcttg ggtcaagact gttgcagtcg tagtcccgtc acctgcgata
     1501 tcattggttt tagaagctac ttctgatacc aatttggcac ccatattttc aaaatggtct
     1561 tctaattcaa tttctttggc aatagtcaca ccgtcattgg taatcaatgg tgagccaaat
     1621 gatttttcaa gaacgacatt gcgacctttt ggtcccaagg ttactttaac agtatctgca
     1681 aggatatcga caccacggac catagctgaa cgggcatctg atgaaaattt aatttctttt
     1741 gacatactta ctttctcctt ctattcttca atgattgcca agatgttagc ttcgcctacg
     1801 atgatatact tttcatcgcc atctttgaca tcaagacctg cgtgggcttc aactaagaca
     1861 cggtctccag ttttaacact tggagcaacc aagtcaccgt tcaaggtacg aacaccttgt
     1921 ccagtagcca caacttgggc tgttttggtt ttttcttggg ctgaacctgc gagaacaaag
     1981 cctccaacag tttgttcttt ttcttctact tttaagacca aacggtcccc taatggtttc
     2041 aacatctgat ttcctccata atgagataga tattattagc actctttata cctgagtgct
     2101 aattcatagt tctattgtat cacttagtca gaaataatca agaaaaaagt ctgactttct
     2161 caagataaaa agcctgagac caactcagac tttttaattc ttaaaatggc aattcttcct
     2221 cttccaagac caaatctgcc aaatcttggc ctgcattatt ttcacgcata gcacgttggg
     2281 cacgactttc caagagttgg aatcctgtca caaggacttc ggttacataa ttcatctgac
     2341 catttttctc aaagcgacgg gtacgcaatt ctccatcaac ggaaatgaga ctacctttgg
     2401 ttgcgtagct tgccaaagtt tctgctagtc tgccccatag gaccatattg acaaaatcaa
     2461 cttcacgttc accgttttgg tctttgtaac gacggttgac agcgatagtt gctcgcgcta
     2521 ctgacttgtc attgttggtt ttgtgcaatt ctggtgtaga cgttaaacgt ccaatcaaga
     2581 taactttatt atacatattt tcttcctcct acttatctat tcgtaggaaa tcaaaaaaag
     2641 ttacagaaat ttgtaacttt tcgagaaaat tttttatttt ttatgaacca tgaaacctgt
     2701 cgcctgttga ttggccataa tggtcatatc tgtaatctga acacgacgag gttgactagt
     2761 cacatagact actgtatctg caatatcctg agcttgcaaa gcttctattc cttggtaaac
     2821 ggacgcagct cgttctttat caccatgaaa acgcactgta gaaaaatctg tttcgacaat
     2881 tccaggctga atggttgtca ccttgatatc cgttgcgatg gtatcaattc gcagtccatc
     2941 cgaaaaggtc ttaaccgcag ccttggtagc tgagtaaaca gcggcaccag cataggcgta
     3001 gattcctgcg gttgacccca tattgataat atgaccttga ttgactttta tcattgctgg
     3061 caagaaacag cgagtaaccg ccatcagacc tttaacattg gtatccaaca tggtcaacat
     3121 atccaactcc tcatagtctt gatagggagc caagtcaaga gccagtccgg cgttgttgac
     3181 caagatatca atcctcccta tcgtttctag aatatcagag caaacagtct tcaccatgac
     3241 catatccgtc acatctagtg gaaaagtcca gacggtttga tttggaaagc ttactgcaaa
     3301 ctccgacttg aggatttcta atctgtctat ccgtcgtcct gttagaacga catcctcacc
     3361 ctgctccaga taagcacgcg caatcgcttc accgattcct gaggttgctc ccgtaatcac
     3421 aacatttttt gccatcttat ttccttctag ctggtctatc agatattaac aacttcttag
     3481 gcagtccagt gtttagctga gtcaaatggt gttccgacaa cttggtcttc tgataattca
     3541 agcaccccac gtttttgtgg agcatttggc agatgcaatt cacgaggact gcacatcata
     3601 ccaaaactct tttcaccacg aagttcacct gggaaaatga gattcccttt tggcatcata
     3661 gctccaggaa gcgcgacaat ggttttcaac cccacacgcg cattgggagc tcctgcaacg
     3721 atttgtacag tcttatcact tgcgactgca acttggcaga tgttgaggtg gtcactatct
     3781 ggatgggcta ccatctcaac aatttcaccg acaacaaact taggttcctt atcattaaca
     3841 atttcttctg taaaaccttc cgcctgcaac tcttggttca aacgagcgac ttgctcatct
     3901 gtcaaaaaga cttgaccgcg ctctgcagtt tcaaataaac ttgaaacttc gaaaatattc
     3961 caagccactg tttccccatt atctttgaga aaaacacggg ctaccttgcc tttgcgctcc
     4021 acatccagtt tggcatctcc gctatttttc acgatgacca taaggacatc accgacatgt
     4081 tctttattat atgtaaaaat cattgtttcc tttttctcct atttcagtcc tgctaaaaag
     4141 tcattgattt gttgcttgct tttacggtcg cgattgacaa aacgaccgat ttccttgtcc
     4201 ttttctagaa caacaaggct aggaattccg taaacatccc agagtttggc caaatccata
     4261 tactgatctc ggtccattcg aataaaggtg aactctggat tggtctcctc aatctctggt
     4321 aaggcaggat aaatataacg gcaatcgcca caccagtctg ccacaaaaag gaagaccttc
     4381 ttgcccgctt tttccactaa agatgctaat tcttctaaac ttgctggctg tatcataaga
     4441 cttcctcctc atagactagg tcttcatttt catagacaaa ggtataatga cggccatcct
     4501 caaaaatgac gccaccaacc aagctctcca gactgctttc gtaaacttga acatagaggg
     4561 tcgcaatttc ccccatgtcg gaaaaatggt ctcgcacaat ctctgtcaac tcttcctgag
     4621 tcttcatgag cttacggtca tctgcaactt ttttcgtagc aagagcaagg cttccaatac
     4681 ctagcagagc caagcctgcc atccacattt ttttagcttt cataccattc attttaacac
     4741 aaaaaaggct tcaggacaaa tgaggaagca gcagaaaagc aagtaaaaag cctcttcctt
     4801 taaggaaaag gacttcgtat actaagagca aactaggaag ctagccgcag gctgctcaaa
     4861 acacggtttt gaggttgtag ataaggcgac gctgacgtgg tttgaagaga ttttcaaaga
     4921 gtattattct tattgccagg cacctaagtt gccaacgtag taaccatcag gtgtgtaggt
     4981 attgcgaaac atcttacttg atgaagccag ataatactac ttgccattgt ctttgaccca
     5041 atcattcgca atcatggaac cagaagaact tacataatac cattctccct tgtcataaac
     5101 ccaagtactg actttcatgg ttcctgagca attaaaggca aaaaaactgt ccaatatcat
     5161 tcgtttttta aaagcatttg acactacatc atctacgctg tagtacatag atacatcaaa
     5221 cgtaaaagcc aaaatatcga aaaatataca acttttaaag gcagcatttc attttttaaa
     5281 gtctaacaac catagaactg aaatcagagc aaggcatcaa tttcctactc ttagtacgtc
     5341 tattttgatg gttgaagtga agattttttt atttaacgta gacaagctcc aacttcccaa
     5401 aggccacgtc tccacgaata atcaaggttt tgcttgttgg cgctacagga gcgtccgcct
     5461 tggctgcacc aaaggatgtt tctactttca aatcgacacg ccagtgttgt ggaacataga
     5521 cggttgcatt tccgaaggcc acttcaatat ttaaagttgc aaaatcacct agcatctctg
     5581 cattatcata gtagatttta gcatccccaa aagcgacttc cacttggtca tctacgagat
     5641 cttgatcttg cttatagaag gtcccgctac caaaagcgac ttccttatcc gtgacgactg
     5701 tttttttccc attgtaccac catttttttt cattccagaa cttacttgaa tgcgtcagat
     5761 aaccaacacc aagtaccacc aagatgctag cccaaataag agaatgattg gtaactggta
     5821 acaagtcata agcgtaattt gcaatgatga gcgccagtaa acctgtaaaa actgccgaag
     5881 tgagatgacg tctaaggatg gactcaatgg acttataagc aaaaaaaaca atacctagta
     5941 aaggccatat tttaccatcc aaagaaggaa ttccaaaatt cccttgcagc aagatccaag
     6001 ctgctaaaac caataaaaca ataccaaatg ctttcttttt catgtttttt acctcatgtt
     6061 tcttagattt tcttttagga gggattggta atgccgtgag acatgaacct ccttgtgcgt
     6121 ctgataaaag gaaatggtgc ccgttcctga aaaggacttg tccactgagt aaatctgacg
     6181 gatgtttgcg atcgttgact tggaaactcg attaaaatag cgaggcaaga tagactccaa
     6241 ctcatagagc ttgaggcgaa cctcataagc ttccttctgg ttatgagcgt agatcttgct
     6301 cccttctgtt tcaaagaaga gaatttctga caggtctaga taatattcac ctgtcccctt
     6361 gtaaaaagtc aacctcggag cctttgactc ttgcaagagc cgttgcaagt ctgcaatttc
     6421 atctgtcaaa gtgggggtct tgatgacaat ttcagtctcc tctaaattgc cgtcaatctc
     6481 aattcgtaac ttcatcacat ctcctttctg actctactat atcaaagcta aattaggaat
     6541 acaagggcaa aaaagcaagt ggtcaatttg aagcagtaag tggttgtagg actagcttaa
     6601 cttacatgtc agaataggaa gaaaaggaat ccccacacca aaccacaagc atagccaacc
     6661 aagacatcct tgggataatg aacaccccct aaaaccctca ccaaccccag caaagctgaa
     6721 aagatcaagc atactaagcc aataggtaga ctagcatgca gacaggccat ggagatgata
     6781 gttgccgaaa agacatggcg actgggcatc gaccgtcccg aactatcctt atcaagaagg
     6841 ggacagatat cccaagtttc ataaggtctc gggtgattga ttttcttacg aaacagggac
     6901 aaggccacaa aacctgatgc aggaataagc acataaaccc caacttgctg accaagtcct
     6961 agttgcaggt aagtggtgac tagcaagatc agatagacca ggggcatggc gactgtcatc
     7021 aaacgattga aactgcgtaa taggaataaa agaattggac gactagttag tctggagctg
     7081 atatttcgat accattcttg ataatttttc atttatgctt ctcatacttt tctagaactt
     7141 gttgagatgt tttccccttg gcaagccaat ccactagctt gtccaagcga cgtatttcct
     7201 gcatcagagg atcatcaatt tcctcaatac ggacaccgca aatcttccct gtaattgcaa
     7261 ttcgttcagg gacataatat ggtgcttgtc taaaaaaatc tccgtaagta acatccctat
     7321 ccagacaagc aagaacatca ctcacttcat accctgtcaa ccaactggtc acttggtgaa
     7381 ctgactctgc ctttccaccc tttcgctcaa cttttgcaat caaggctaag tagacagcag
     7441 caaatttcat attgtataat ttctgactca tacttctctc tttctatgtg tactagtata
     7501 aataagaaaa agaaggccgt caagccttct tttgatttat tcttctgctt catcttctgt
     7561 aaattgacta ttgtacaagt cagcgtagaa gccaccttgc gccatcagtt cctcatagtt
     7621 gccttgctcg atgatatttc catctttcat gaccaagatc aagtctgcat ttcggatggt
     7681 tgacaagcgg tgggcaatga caaaggatgt gcgtccttcc atcaaacggt ccatggcttt
     7741 ttggatcaat tcctctgtcc gtgtgtcaac agaagaagtc gcctcatcca aaatcaaaag
     7801 cggtgcatcc ttaagaaggg cacgagcaat agtcaatagt tgtttttgtc ctacagacaa
     7861 ggtcacggtg tcatccaaga tggtatcata gccatctggc aaggtcataa taaagtggtg
     7921 aattcccaca gccttactag cttccatcat tcgttcatca ctaatcccta tttgattata
     7981 gatgagattg tctcgaatag ttccttcaaa gagccaggta tcctgcaaga ccattgaaaa
     8041 ggcatcatgc acttctgaac gcgtcatagc cttggtatcc acaccatcaa tgtgaatact
     8101 tcccttatca atctcataga atttcatcaa aagattgaca atggttgtct taccagtccc
     8161 agtcggccca acaatggcaa ccttttgacc agcatgagct gtcgcagaga agtcatagtc
     8221 ttgaacattg acaccgtcca ccagaatttc tcctgctgac acgtcgtaga aacgtggaat
     8281 cagattgacc agagttgatt taccagaacc tgttgaccca ataaaggcca ctgtttgacc
     8341 agtttctgct ttaaagctaa catgttcaat aactgcctcc gaatttgccg catagcggaa
     8401 ggtcacatcc ttaaactcga cctgaccttt gaagttttca tcagtcagct gtacttgaac
     8461 agggttttgg atagaagaat gcaaatctaa aacttgatta atccgcttag cagagaccat
     8521 agttcgggga agaacgatga agagtgctcc catgagaagg aagcccatga caacctacat
     8581 ggcataagac atgaaaataa tcatgtcact aaagagaggc agacgcgcta tcggagcagc
     8641 gtcgttaatc acataggccc caatccagta aatcgctaca ctcaaaccac ttgaaatccc
     8701 catcatgata ggattcaaaa tagccataag acggttgaca aacaaattca aacgggtcaa
     8761 ttcatcattt actgctgcaa atttttcatt ttgataatcc tctgcattgt aggcacgaac
     8821 gacacgaata cctgttaaac tctcacgagt gatactgttc agtttatctg tcaacccctg
     8881 aatcaaggac tgttttggaa aggctagcgt catcaaaacg gtcgtcatca ggacgttgac
     8941 aatcactacc acaagtacgg cccagagcca gtattctgaa tgacctaaaa tcttcccaat
     9001 agcccagata gccataattg aaccacgcgt taccacttgc aagcccatag taatcaacat
     9061 ttgaacttga gtaatgtcat tggtagtacg cgtcaagagg ctaggaattg aaaatttctt
     9121 aatctctgtc tgcgagtaat ccaaaactcg gttaaaaata tcacttctca gcctactagt
     9181 ataagaagcc gccactcggg atgcaaaaaa tccaactgca actacggaca agaaggcaag
     9241 aaaggacatt cccatcatca tgcttgccgg ctgccacaac tcatctaaat tagtttcttg
     9301 actacctagc aaatccgtaa ttttcgagat ataggtcggc acttccaact ctagatagac
     9361 cgaaaagcaa gtaaagagaa tggctagtaa aatcatcccc attcttttct actaattctt
     9421 ttggctaatt tctttattct ctcctcctat tcccttgata tttgcctgta gttgaccgag
     9481 aactttctca aaaatcagta attcatcttc atcaatgtct tccatcaact gcttgtctat
     9541 gcgttcaaaa aaagccttaa cctgttgcat ctgagaacgt gctttgtccg tcagacgaac
     9601 aaacttagcc cgcttatcaa caggactcgc ctccaattcc accaaaccat tttgcactat
     9661 acgcttaacc agattactag caacagactt ggtaatattg agttcctgct cgatatcttt
     9721 aatcaagacc aagtcttggt ttttctcgcg attatccaaa aaacgcacaa cctgaccttg
     9781 cggcccaccc ataaattcaa tgccgcaacg tttggcttcc ttttgcacca tcaggtgaat
     9841 ttgatgacca aaacgcttaa agactaacat cggtttaccc ataatctccc ccttctaaat
     9901 aaaaatagtt ctctggagaa taattaaatt tctatgagaa ctattttctt gattaaaaaa
     9961 atcccaagtg attttctcac ttaggatcat gttctatagg ttaaattaaa acccatctac
    10021 gttcgtataa atcttttgga cgtcttcgtc gtcttcaaga acgctgtaaa gtttttcaaa
    10081 ggtttcaagg tcttcgcctg acaattccac ttctgactga ggaatcattt ccaattcagt
    10141 cacttggaat tcttcaatac cagactcacg gagggcaacg atagccttgt gaaggtcagt
    10201 tggcgctgtg taaactgtga ttgtaccttc ttgtgcttct acgtcatcca catccacatc
    10261 cgcttcgagc aattgctcaa agactgcgtc cgcatcttca cctccaaata caataacacc
    10321 tttgttgtca aagaggtaag aaacagaacc tgaagcgccc atgtttccgc cgtttttacc
    10381 aaaggctgca cggacattgg ctgctgtacg gttgacgtta gaagtcaaag tatccacaat
    10441 tagcatagag ccatttggcc caaaaccttc gtaacgtcct tctgtaaagg tttcgtctgt
    10501 gtttcctttg gctttatcaa tcgctttatc gataatgtgt tttggcactt gggcttgttt
    10561 agcacggtcg ataacgaatt tcaaagctga gtttgattct ggatctggat cacctttttt
    10621 agctgctaca tagatttcta caccaaattt tgcatatact ttagagttag ctccatcttt
    10681 agccgttttc ttggctacga tattggccca tttacgtccc attaggaatc tccttttttc
    10741 acattttaat ctttcttatt ataacacaag tttttttgat tttcactaga ggaaatggat
    10801 tttattagca aatcaagcta ggatagcact ttacctgcta agacggtctt gcctttctat
    10861 ctttatcaac agacactcat ccacattcaa aaaacaaact agaccattat ctgcaaatag
    10921 aaagtttcag ccaagtttga caaagtcagc tcaaattact gtttgaagtt tgtagatata
    10981 agcgacaaaa acaatcatac tgcacctttt gttgacagtc tactccagac atatcatagt
    11041 tcaagtaaat actttgaaat ccaacagttc ttataggcgc tattgtattc taagaaatca
    11101 atagaagagt ttctaagcaa acctctaata ctcaataaaa atcaaagaac aaaccagaaa
    11161 gctagccgca ggttgctcaa aacactgttt tgaggttgcg gatagggctg acctggtttg
    11221 aagagatttt cgaagagtat aatttacgtg ttcccaagat ggagaagtta gactagtaca
    11281 ctggcacttc taaaccattg ctagcaattg atttgttcat atttaatttc attttttcca
    11341 taaatgggta ttagatataa acagcaaaat atttccgata cgtgtcattc ttgaatttcc
    11401 aatcatctaa aacaagtaaa ggataatcaa tcccctgtat atcaaggaat tggctaccct
    11461 ttttactttt ttacacatcc tgtttgatag actcatttta acatcacgag catactccaa
    11521 tggaaatcgc taggcaagag ataaactttc agatatccgc agagagatca tcgcctcttt
    11581 ttgtcgcaag cattctcttc tcctagtcat tttctacctt atcttctacc tgaggataga
    11641 gagttgttcc ccaaatagaa atcgtccgct tacgcactag tggcaaatcg gttttttcat
    11701 aaaccgtacg ccaccattcc caggcaagcc cggtacactc tctaattttg acagagagat
    11761 tacgaacatt cccttttaaa ggaatactag tggtaaagtg agccgtcaaa tcctgcccat
    11821 ttctgtccca agccttagga gtcaagactt ccttaccttg atgatcatag gataattcat
    11881 cccaagtaat ataatattgg gcaacatagg caccactatg atccagcagt aaatctccgt
    11941 ttctgtaagc tgtaacctta gtctcaacat agtctgtact gttttgaaag gtcgcaacta
    12001 cattgtcacg taaaaaagaa gttgtatagg aaatcggcaa gcctggatga tctgctgtaa
    12061 agcgactgcc ttcttgaatc aagtcctcta ccatatccac cttgcctgtt acaactcggg
    12121 cacccgaact tgggtcgccc cctaaaataa ccgccttcac ttctgtattg tccaaaatct
    12181 gcttccactc tgtctgagga gctaccttga ctcctttcat caaagcttca aaagcagcct
    12241 ctacttcatc actcttactc gtggtttcca acttgagata gacttggcgc ccataagcaa
    12301 cactcgaaat atagaccaaa ggacgctctg cagaaattcc tctctgtttt aaatcctcta
    12361 ccgttacagt atcttgaaac acatctcctg gatttttaac agcgtctacg ctgactgtat
    12421 aataaatctg cttaaaatta acaatctgaa tctgcttttc acctgaatgg acagagttaa
    12481 aatcaatatc aagagaattc cctgtctttt caaagtcaga accaaacttg accttgagtt
    12541 gttccatgct gtgagccgtt attttttcat actgcattct agctgggaca ttattgacct
    12601 gaccataatc ttgatgccac ttagccaaca aatcgtttac cgctccgcga acacttgaat
    12661 tgctggggtc ttccacttgg agaaagctat cgctacttgc caaaccaggc aaatcaatac
    12721 tataagtcat cggagcacga tcaaccgcaa gaagagtggg attattctct aacaaggtct
    12781 catccactac gagaagtgct ccaggataga ggcgactgtc gttggtagct gttacagaaa
    12841 tatcacttgt atttgtcgac aagctccgct tctttctttc gataacaaca aactcatcgg
    12901 gtagctgatt accctctttg atgaaacgat tttcaatact ttctccctga tgggtcaaga
    12961 gtttcttttt atcgtaattc atagctagta taaagtcatt tactgcttta tttgccatct
    13021 tctacctcct aataagttcc tggattgagt tgcataaact cagacttgtt cagcgaaatc
    13081 agccgtggtt ggactaagtg atccaaaatt tcctcgtaca attcttctga gacattgcgt
    13141 cgccgtctgg ctagataaga agtcggaata accgtattat ccaacataaa taccttatct
    13201 aagtcaatca aggttggtct tgtaaaagga ttacgagcta gatccggctc ttctatcata
    13261 aagttcttga ccaaacgtct ggtcaagaga gctggtttga aggtctgatt tttaaccaac
    13321 tctttgtttt tagtcatgct gttgtcaata cagatataca tatgattctt cacagccaaa
    13381 tcgctactaa tagtcggaaa aggcaaataa agaactacaa catctcctct cttaatcaag
    13441 caagagcacc cccttttctc ctaatgtaac atagacagga ttgaccaagt cttctgattg
    13501 actcagaatt tccaaagttt gagtttggcg cgctgtcaat ttagtagcat cttgtctctt
    13561 caatacaaaa tgcttgtcgc caataacctt gacaatataa tccttctcca aagctgactg
    13621 gtaaatccac atcagatgtt gtctgtcctg agaactcaag agagaaggat tttcaagcct
    13681 cccgatagtc tgataaaaat caaaaacagg agctaactcc tgccaatctg attggctagt
    13741 tgtcaaggct agaaaaaggg ctttgcgagc tgatacttct tggttagcct tgagagttac
    13801 tttcccctcc aagtttttta gaaatcggga aactccagaa agcaaatttt tctctaactg
    13861 cgagaaataa aaacctttcg ttcccagaca taagtctttc atgtcgcttt ctctagcaaa
    13921 taagagctca aacatttgat agtaaaagaa aaatatctgg cactgggtcg cgctcatctt
    13981 ttccttatcg gcttcttttt ttaaccagag caagggcgac aggtagctgg attgagacat
    14041 ttcctctacc tcctactctt ttttaactgg agcatctgca ctagctgcca cttcttttga
    14101 ctggatactt tcccactggt taatctcctc tgagataaga ccttcgcatg tcttgacaaa
    14161 tagggcaaaa gccttggtct ttcctgcata tttctccgtt tggcattgat agaggaattt
    14221 ttctttctcc aggagttgcg cagttttttg gtaagaaatc caattttcct ttgcattata
    14281 caaattgata atcccctcac acagcaagcc gagactggat aaggcaaccg aaatcaaacg
    14341 gtagcgatca cctggcatag gaatagcaca aaagacagct atgaggaaac ctgccacgat
    14401 ttctgttatt tttaatacct tatagcgtct acgatgttga acgcttttct ttaaaaaatg
    14461 agctatctgt acgtctaatc gctctgtcag gtacatttct tctggcgtca tattcgtaac
    14521 tcctttcatt tactttgata accatagtat aacatatttg aatatcaaag tatagtaaaa
    14581 actggactat aacttattag acttcctgcg aaacaaaata tggtatagta gttctatgaa
    14641 ttatgaagca agtaaacaac taactgatgc acgatttaag cgtcttgtta gtgttcagcg
    14701 taccactttt gaagagatgt tagctgtatt aaaaacagct tatcaaaaaa gtcggacaag
    14761 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
    14821 aaactccacg ta
//
LOCUS       DBEROT010000046        14428 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.46, whole genome shotgun sequence.
ACCESSION   DBEROT010000046 DBEROT010000000
VERSION     DBEROT010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.46"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..586)
                     /locus_tag="ACL8CG_001806"
     CDS             complement(<1..586)
                     /locus_tag="ACL8CG_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1344357.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEI"
     gene            complement(583..1065)
                     /locus_tag="ACL8CG_001807"
     CDS             complement(583..1065)
                     /locus_tag="ACL8CG_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HGS1344358.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(1062..2198)
                     /locus_tag="ACL8CG_001808"
     CDS             complement(1062..2198)
                     /locus_tag="ACL8CG_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344359.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
     gene            complement(2205..2501)
                     /locus_tag="ACL8CG_001809"
     CDS             complement(2205..2501)
                     /locus_tag="ACL8CG_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HGS1344360.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(3044..3937)
                     /locus_tag="ACL8CG_001810"
     CDS             complement(3044..3937)
                     /locus_tag="ACL8CG_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1344361.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(3958..4152)
                     /locus_tag="ACL8CG_001811"
     CDS             complement(3958..4152)
                     /locus_tag="ACL8CG_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344362.1"
                     /translation="MKKVLKYFLVFVFLFLMNIFIFKILATLGFQLIMSEKSYIVLPL
                     FSLIVLYMIDKRIRKKKKSL"
     gene            complement(4563..4688)
                     /locus_tag="ACL8CG_001812"
     CDS             complement(4563..4688)
                     /locus_tag="ACL8CG_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS1344363.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(4691..4921)
                     /gene="blpU"
                     /locus_tag="ACL8CG_001813"
     CDS             complement(4691..4921)
                     /gene="blpU"
                     /locus_tag="ACL8CG_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGS1344364.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(5124..5414)
                     /locus_tag="ACL8CG_001814"
                     /pseudo
     CDS             complement(5124..5414)
                     /locus_tag="ACL8CG_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(5460..5693)
                     /locus_tag="ACL8CG_001815"
     CDS             complement(5460..5693)
                     /locus_tag="ACL8CG_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS1344365.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(5699..6691)
                     /gene="plsX"
                     /locus_tag="ACL8CG_001816"
     CDS             complement(5699..6691)
                     /gene="plsX"
                     /locus_tag="ACL8CG_001816"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGS1344366.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPMRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTIDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(6688..7458)
                     /gene="recO"
                     /locus_tag="ACL8CG_001817"
     CDS             complement(6688..7458)
                     /gene="recO"
                     /locus_tag="ACL8CG_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGS1344367.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQNLTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(7455..8624)
                     /locus_tag="ACL8CG_001818"
     CDS             complement(7455..8624)
                     /locus_tag="ACL8CG_001818"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1344368.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            8773..9783
                     /locus_tag="ACL8CG_001819"
     CDS             8773..9783
                     /locus_tag="ACL8CG_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGS1344369.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFISKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(9812..10015)
                     /locus_tag="ACL8CG_001820"
     CDS             complement(9812..10015)
                     /locus_tag="ACL8CG_001820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344370.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHRFEVADRTDEVS
                     SKHRFEVADRTDEVSNIYTARRR"
     gene            complement(10056..10493)
                     /locus_tag="ACL8CG_001821"
     CDS             complement(10056..10493)
                     /locus_tag="ACL8CG_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGS1344371.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(10578..13211)
                     /gene="polA"
                     /locus_tag="ACL8CG_001822"
     CDS             complement(10578..13211)
                     /gene="polA"
                     /locus_tag="ACL8CG_001822"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGS1344372.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPVLLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            13467..14374
                     /locus_tag="ACL8CG_001823"
                     /pseudo
     CDS             13467..14374
                     /locus_tag="ACL8CG_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
BASE COUNT         4477 a         3236 c         2325 g         4390 t
ORIGIN      
        1 aaatttcata aacccgtcct tcctctatta aaatcctttg agatttgcta atcaattctt
       61 gattcaataa attatgagat acatatataa tagtagagct ttctttcatg gaaattaagc
      121 gtttagcaat catatcaata cttcttgcat ccactgttga taaagtctca tcaataaaaa
      181 tataatccca atttttagca aaaattaagg ataagcctaa tttgaatttt gttccagtag
      241 atgctgtcat atagttatct ccgattttat tatcaaaaaa agtattaatt tgttctttat
      301 cctcaaatga tagatggatt tgaaaagaat cacacaacaa ctgcaaattt tcttctatag
      361 taaatggaac aaccccaagc tgattggtat caaggtatag tacatctttg gagacacaat
      421 tctttaaacc actatcaaaa gtctctagcc cagctaaaag ttgtagaagg gtgctctttc
      481 ctgaaccatt ctctccttca actctgtaaa ttcccttatc aatctctagt gatatatttt
      541 tcaatataca tttatcataa cttttagatt cattttcaat tttcataatt taattccctc
      601 tatcaacgct gctaaaatta ataaaagata agaaatgata taccatttta aattactttt
      661 tatataaata agtatatttt taattcccct atccttcaat aatcggtata aaagatactg
      721 actcatacct tgataccaaa taaaattcgg tatttcaata agagcatgag gtaatattcc
      781 ttttattgta gctactattc caatcatctg accagatata cccaattgta ttcctaaaga
      841 tagcaaatca aaaagttgca ataagggcga aatcggaaaa cagaatagat atagcaaaaa
      901 atttgtagaa tttgcctgta aaactgtcaa tgtaaattgt aattccagtt tcggaggtat
      961 agtagcaaaa gtctcatttt ttaatataaa gcttaaaagt aaacctagta aaaaacagac
     1021 tatacaaaat aacacatagt aaatcagaaa accacttttt ctcatctaat gccccctact
     1081 aaaattacaa atattatcag aaaacaatat aaaaccagaa aactccatct caataaacta
     1141 actgtacctt taattaaaaa tagagctttc ttataataga cataggctat aaaataattg
     1201 aatggaatca ataacaaatt caacaaaata ctttttatat cattactata acttgtcacc
     1261 ggaatcaaac ataacaacaa tgaaaattgt aagaaagaga ttaaatgcgt caacatcatt
     1321 agttgtgcat tcttaaaaaa gaaattcatt ttagaatgat taagagcaga taattgaagt
     1381 aaagctagat ctaccccaat tgaggattta tgattcccta ttattgcctc cattaatgta
     1441 atatatattg aggtataaag aaataatatt ggtatttttg tgtcatcaat tgataacatc
     1501 gtcatcatat accaaaatag ataggaaaga agaatactaa tcaaaataaa agaaaaagtt
     1561 aaccctttat ttaaccaaca aaaacgaagc aatataaata gactgctacg aaatcttttt
     1621 tgactcattc gactgctttt aaaatagaaa ttactcgcat gattatctaa tatccccata
     1681 actaaaataa aataattgag tagtatgaca taaattacaa cttgtccttg ttctatagac
     1741 aatagtccta tagataaaaa taagaacaat ttacttataa ttgaaaacaa actaggtaga
     1801 attaaagaaa taatttgaat agctatcaaa caaagagtaa tggataaata aaaatatcca
     1861 ataatatcta gaaaatacaa aataaataaa taaatgaatg attgtaaaat ttggaaagaa
     1921 taatatttct tgacaatggc aagaagatag agaaaaatat agtttttcct tatatagaaa
     1981 gtatttattt ttttactttg gataggcagt ttcatattat aacgattcaa agtagcgtaa
     2041 tctactacca aaaaaagtaa aaataatttc ccttgaaaag gaagatagct tttaaaatag
     2101 attgacaaac ttatgataac aaaaaacaaa agggttatcc caataaaatt aagataacct
     2161 aaaatacttt cacattcttt tttagaaagt attttcatct agttctacca tagagctgct
     2221 ttagcagcac ctttcttttt caatatataa agaactgttg ctgcaatacc cgaaccaata
     2281 gaacctactc ctgtgattgc acctacaatt gaaattactg ctgtaactgt actataagca
     2341 ctaatcaaat tgactacagt agcagcagct tttgtcgaaa ttcctaatgt cccagccaac
     2401 ataggaaaag aaacaacacc taagcttaac caactaatga ctgctaacat tgctgaaaca
     2461 ataagaaatt tattatgaaa ttccattctt ttagatttca ttttagtgta ctccttttgt
     2521 atattatgta tgttttattg agagttaatt cgcacatgtt gtattcctaa ctctcttcaa
     2581 atgttcgtct atattttata ctacttttat taacatatct ataataaata aattactact
     2641 acattttcct agattatcaa attactttta tatcactaag actcaataaa agataatgtc
     2701 tatttaactt ttatacgatt actacctcct ttttagttta cacttcctac atcataaata
     2761 aacatactaa accctcacaa tctccaaata actcttctat atcattgaaa attgagtttc
     2821 atcctctata ctaatgtagg aaacctatta aaacattcct ttaatccaat ataagaatac
     2881 cttgttccat taatctctac ccgatattat agatagaacc aaattcctat acttaaaagg
     2941 acaaataacg ttccaaccat aataaacctc ctttcttttt gagaacgttt tctttatagg
     3001 tttagtgtag caaaaacatg aaaaaaacaa catgacttag aagtcaggtt gttgggaaat
     3061 ctatctgttt ttctgctaaa attctctgaa ctaatacctg atcgtctagc aattctgcta
     3121 gagaaatcgc cttttcatag aaactttctg cctctaaaat attcttgtct acaaataaag
     3181 catattttgc ctttagcaaa aatagatgag gtcggtaaaa aacatgtctt gttttagcaa
     3241 taattttctc aaatgtttga atatatatca gactatcttc tgtctgaatt tggataaata
     3301 ggctcagaag aactttttcc atttgaacta ggctagcctt atcttcatat tctgaacata
     3361 gcaatacttt ttgagctaac tcctcaaaat gttctttatc ttctaatccc atagcacaac
     3421 aaaagaaata caattcaata atcaacaaat catttacaga aaaatatttc ttttttaata
     3481 actgctggaa atattcttcc actaacccta aaccgtaggt cacatctgaa ctaccataaa
     3541 tatcaaaacg agcttgtgtc acatccacaa ttaactgctc ttcctcaggc aaattctcat
     3601 aatagttttc atatatttcc tcaagtatag cttcttttcg ttcgattctt cccttatcag
     3661 cgtaggtttg agaatgaatc agctcatctt tgagttttag gaatcctttt ggaatctcta
     3721 taaccttaac atccacaata ttctgtaatg atactccaag tttatccgca atcaataata
     3781 atttaggaag tgttgctaaa gcttgcccat tttcaatacg tgctagctga cgaatcgtca
     3841 actctgattc atcaccacaa atatctatct gagtttttcc acaagatcgc ctaatagttt
     3901 tgattttata accaatttca cgtttcaact catccatagt aatactcctt aagttgatta
     3961 caaagatttc tttttcttcc taattctttt gtcaatcata tataaaacga taagcgaaaa
     4021 cagcggtaga acaatataac tcttttcact cattatcagc tgaaatccca gggttgctag
     4081 tatcttaaag atgaaaatat tcatcaaaaa tagaaaaaca aatactaaaa aatattttaa
     4141 aaccttcttc atttcttttc ttcaactttc ctaatttcta cacctatttt atcgaaaata
     4201 tatataaaac tccaaataaa cacttcgact gcactttttt tggcaaaaaa tagacagaac
     4261 aaacatccta cctactaaaa atatgatatg aaaggaaaat gattttttac tgacacccta
     4321 ggcaagcttg ggacaaataa atcattgata gcaacattta cgacatccta tttaaagttc
     4381 cttcaatttc taatgtcccc gctatttcta agccacctct ggtatgatct attcctagtc
     4441 agaatagata acaccgttct aaattacgat tcatagttac tccttttttg actcgttact
     4501 ataagactcc tatttacatg cgcaaaataa ttttgattca gattcatcat ttatagtttt
     4561 gattattttt taacagattt ttctgttttc ttctccgaag actttaaaaa tttttttcta
     4621 attaaatcat ccatataagg accaaatata ccaactacta aaccaataat aaaactttta
     4681 aaatccataa ttaccaccaa catgtcgctg cataggccac acctccaagt atagctcctc
     4741 ccacagcacc agttgctgca ccttgccatg ttcttgtttt aattcctagc tgaagacctc
     4801 gtgctgctcc tcctccaaca cctgctttgg caaaatctcc ccaattgcat ccgccacctt
     4861 caacgcaagc aagcatctca gtatccataa tttcaaattg tgacatcgtt tttgtattca
     4921 taacgaatac ctctttttta tttttaatat ttgtcttgtt acaaacttga caagtttagt
     4981 ataacagtat ctattaattt ttttcatcca aatcttgaat tggcatcgaa acgtcttgaa
     5041 ttagcttttt tgtttcaaaa tcatctctat ttttaaaaaa gatgttttct aatcactttt
     5101 ttactattag acttcctgca aaactagaat cctagttcat gattgataat accagcaatc
     5161 aaattcattc gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaacatttta
     5221 aacgttttta ttttggcaaa gatattctca accttgcttc tctccttaga tagcgcatga
     5281 ttacaggctt tatcttcaac tgttagcggc ttgagtttgc tggatttacg tggagtttgt
     5341 gcttgaggat atatcttcat gagcccttga taaccactgt cagccaagat ttttccagct
     5401 tgtccgatat ttctcatttc taaaaaccat ctacttccgt tgacttggaa ctccgattgc
     5461 tattttcctt gaatgatttt aaccacatct cctacgtttt ggagttggtc aatttcttca
     5521 tcgctgattt cgatactaaa ttcatcttcc agagtcaaga taaactccat caagtcaaca
     5581 gaatccgcat ccaaatcgtc tttcagactc aaggattctg tcacgacaaa gtcctctccc
     5641 tgtcgctctt ggataatggt cacaatacgg tcaaaaattt ctttttctgt catctctttt
     5701 attctcctga aaattcacgc gcagtctggg caactacgtc tgtttctagc atggtacgaa
     5761 tctggcgaat cgtactataa acagccttgg catcgcttga gccatgagtc ttgacaacag
     5821 gtgccttaac accaaacaag accgctccac caacatctga ataattgagc tgttttttca
     5881 aaccactgag gctgtccttg agaaggaggg cacctagttt cgctcgaaga ccaccacctg
     5941 taatagctgt cttgagcaag cccatgattc ccatagctgt cccttcgatg gatttgagca
     6001 cagcgtttcc cgtgaaacca tctgccacaa caacatctgc aacgccattc atcaaatcac
     6061 gcgcttccac gtttccgata aagttcaaac tttcatcagc cgccagtaat tcataagttt
     6121 ccttacgaag cgggtcgccc ttgctactct ctgttccgtt gttgagcaaa ccaacacgtg
     6181 gttgcgcaat gccacgaaca ttcttggcat agaaagaacc taggacagcg tattgatgga
     6241 ggtgctgggc tgtattttct gcattagcac cgaggtcaag catgtcaaaa cctttcccat
     6301 ctatagtcgg caatgttgac ataagtccag gacggtcgat attcttgata cgacccacga
     6361 tgaagaatcc tgctgccaac aaggcacctg tattcccagc cgaaaggaca gcgtctgctt
     6421 caccatcttt gacagccttg gctgccaata ccatactggc atttttctta ttcctaatag
     6481 ctctcatagg ttcatcatcc gaatcaatct tctcatccgt atggataatg ctgacgcgct
     6541 ctgtcgctgt cagatattgc ttgattttag cttcatctcc gtaaagttga acctcgatat
     6601 ctgaaaagtc agatagggct tgattgacac cctcaacaat ggcctgaggt gcgtaatcgc
     6661 cccccatggc atctactgcg atttttttca tttcttttcc tcttttagta attgtcccca
     6721 gtctgctagg gaatcaataa atttctttga ttttaggtga atcccaacgt actcttcata
     6781 taattgatcc ataaattggc gtagctcttg cttgattcca ggcttgagcg aaatggtctc
     6841 caaagtctca aaatcaatag cttgaaattg attgagcaga taggggatat tgggattgag
     6901 atgacaacgt ctcttatcct catgataatg ctctggacag aggcaggctc catatttgaa
     6961 agaaaagtca aaagcctgac caacccgatg gcagaagaca cactcattaa aattgaggct
     7021 gattccaaat cgagtcaaat tttgaatttc aaaaatattg gtcaaaacct gataatccaa
     7081 gcctgcttcc atcaactcca aagtcttttg caaaaaagca aacaagggag catcctgctg
     7141 attgtcctgc aaactagcat ctgcaagagc tgccacatag gtcgcatagg ccatgacaaa
     7201 gaggtcacta ttaatcttgg gaaaagtcat gacctcatga tagtcttcga tgtaactgag
     7261 tccgtcatca ttgattcgca agagaaatcg tgccagcacc aagggctgaa taacaggcgc
     7321 cagcttagac tgaccagcgt gtttgacaaa aaacatgcgt ttgccaacct gctctgtaaa
     7381 aattttgacg agcttgtcat cctcacgaaa attgcgattg taaagcacca agccttgact
     7441 cgtgatagac tgaatcatgc ttctctcatg tactcctcaa gtcgtttcat ggcttctttg
     7501 atagtctcca tgctggctgc ataagatagg cggacgtagc cttccccgta acgtccaaag
     7561 gctgcaccag ggataaaggc aacggccttc ttctgagcaa aatccttcag aaaagcaaag
     7621 gagtcttgat tgtagcccgc tggaatttta gcaaaaatat agaaggcacc gtctggtttg
     7681 ataatctcaa aaccaagagc agtcattttt tcgatgatat agtcccgacg ttggatatat
     7741 tccttcttca tgggctccgc atcgttttta ccagccgtca aggcttctac cgcagcatgt
     7801 tgcgccatgg tatttgcggc agtgaccaag tactggtgac tcttgattaa ctgggctgtg
     7861 aaggtcgcag gagcgaaaat cagccccaaa cgccaacctg tcatggcatg cgatttagac
     7921 aaaccattga taataatagc ctggtctctc aacatcgttc ctagagacac atgggcttcg
     7981 cctgtgtagg tcaattctga gtaaacctca tcacagacaa caaaaatttc gtacttgcgt
     8041 aaaacagctg ccaaggcctc taactgctct cgactgtagg taattcctgt cggattggct
     8101 ggatagttga gaataaccgc cttgagctta tcaccctgct ccaaaatggc cttctccaac
     8161 atctcaggag tcaagacaaa accattttca gtcgtatcaa tctcaacaat ttctgcccca
     8221 actaagttaa caatcggttc atagcctgga taagcaggag ctggcaaaag taccttgtct
     8281 ccctcttcca aaatagccgt caaagtcgca gataaagcct ctgtcgctcc gatagtgacc
     8341 aagatttcat tttcaggagc atagtccagt tggtactttt ccttaacaaa atcactggcc
     8401 gcctgacgta gagtcagcag accactcatc cctgtatagt aggattggtt ctgatcaatc
     8461 gctcgcttgg ccgcctcctt gacatggtct ggcgttgtaa aatcaggttc ccccaaggtc
     8521 aaacgcaaga ccccaggaat ctccgaaata gcctggtcaa actgacgaat caacgaaact
     8581 tgaattttat ctaactgttt attaaagcgc ttagttaagt ccatagatac ctcctacttt
     8641 caaaacgtat ctctattata ctacaaaagc cccccgaccg caaaaataca ttagagaata
     8701 gctttccact ttctatttta cttttcctgt ttataggtct ataatggtaa tagattttat
     8761 ttggaggttt ttatgtcatt tctatcaaaa aatggagcag gtatcttggc ctgccttctc
     8821 atttctatcg tatcttggta cttaggagga ttcttccctg tgattggcgc gcccgttttt
     8881 gccattttca taggcatgct cctacatccc tttctctcgt cctataaaca actggatgct
     8941 ggtttgacct ttatttccaa gaagttgctc caatatgccg ttgtcttgct tggttttggt
     9001 ctcaatatct cgcaggtctt cgcagttggc caatcttcac tccctgtcat cctgtccact
     9061 atctcaatag ctctgattat tgcctacctc ttccagcgtt tctttgcact ggatacaaaa
     9121 ctggctacct tggttggagt aggttcttct atctgtgggg gttctgccat tgcagcgaca
     9181 gcgcccgtta ttgatgctaa ggaaaaggaa gtagcccaag ccatttccgt tatctttttc
     9241 ttcaatgtct tggctgcgct catctttcca accctcggca cctggcttca tctatccaat
     9301 gaaggcttcg ccctctttgc agggactgcg gtcaacgaca cttcctctgt aacggctgcc
     9361 gccagcgctt gggacagtct ttaccaaagc aataccctcg agtctgcaac cattgttaaa
     9421 ctcacacgta ctttggccat tatccctatc acgctctttc tatcctactg gcaaagtcgc
     9481 caacaagaaa acaagcaaag cctacaactg aaaaaagtct tcccactttt tatcctttac
     9541 tttatccttg catcgctcct aaccaccctt ctgacctctc tcggtgtgtc tagtagtttc
     9601 tttacccctc tcaaacaact ctctaaattc ctcattgtca tggccatgag tgctatcggt
     9661 ctcaaaacca atctggtcgc tatggtcaaa tccagtggaa aatccattct tcttggagcc
     9721 atctgctgga ttgccatcat cctcaccact cttggtatgc agacccttat cggcattttc
     9781 taatactctt cgaaaatctc ttcaaaccac gtcaacgtcg ccttgccgta tatatgttac
     9841 tgacttcgtc agttctatct gcaacctcaa aacggtgttt tgagctgact tcgtcagttc
     9901 tatctgcaac ctcaaaacgg tgttttgagc tgacttcgtc agttctatct acaacctcaa
     9961 aacagtgttt tgagcagccc gcggctagtt tcctagtttg ctctttgatt ttcattgagt
    10021 ataacacaaa aggtagccca tcagctacct ttttcttatg cttcctcaat caagcgagta
    10081 tgttctctct tgatacagcg attcatcacg atatcatcac atccaccatc acgcaaaatc
    10141 tctttcgctt ctaaactttc aagtcctagc tgtgcccaaa aaatcttggc atcagctttg
    10201 agaaaatcac gcgccacatc gggcagaaat tcactgcgac gataaacatt gacaatatct
    10261 acaggaaaag gaatttcagc gaggctagca taagcctttt cacccaagat ttcgccacct
    10321 gccgccttgg gattgactgg gatgatttta tagccccgag cctgcatttc ctttgtcact
    10381 cgattgctgg ttgtttcttc acggtcagac aaacccacca cagcaagggt tttactcgtt
    10441 gcgagatact gacgaatcac gccatcactt ggattgataa attcttgact catagaaaac
    10501 ctcctttttc atcagtatag cacattttga aaaggtttgc agaattctac tacaaaaaag
    10561 gaggactagc ccccttttta tttagcctcg taccaggttg ccccttcatt ctcatctgcg
    10621 ataagaggaa cactgagttg aatggcttct tccatggttt gtttcaccaa ttttttcatc
    10681 tctaccaatt cagatttagg cacttcaagg acgatttcat cgtgcacttg taacagcatc
    10741 ttagtctgat aaccacctgc aaccaaggct ttatccagct gaatcatggc aatcttgaga
    10801 atatctgctg ccgaaccctg gataggtgag ttgatagcag ttcgctccgc aaaaccacga
    10861 atattgaagt tgcgcgaatt gatatctggc aactcacggc gacgcttaaa gagggtctct
    10921 acatagccct tatcacgcgc ctcccgcacc acttcatcca tgtagttttt aatacctgga
    10981 aaacgttcaa agtaggtatc aatgtaggct ttggcttcct tacgactaat tcccaaatta
    11041 ttagacaagc caaagtctga aatcccataa accactccaa agttaactgc cttggcattg
    11101 cgacggtcat ttgcagtcac attatcagga cgctcaatgc caaagacccg catggctgtc
    11161 gaagtatgga tatctgcccc ctcttggaag gccttaatca agtgctcatc cttagaaata
    11221 tgcgccaaaa cgcgcaattc aatctgtgaa tagtcagagc tgagtagcac actatcctcc
    11281 cactctggca caaaagcctt ccgaatcaag cgcccctgtt ccaatcgggc aggaatattt
    11341 tgcaagtttg gatccacact agacaaacgc ccggtctggg tcaaatcctg cacatagcga
    11401 gtatgaatct ttccatcagc caaaatccag tcctgcaagc caattacata agtagattga
    11461 atcttagcaa tttgacggta atccaggatt ttcttaacaa tcggagcaat aggagcgaga
    11521 cgctccaaca catccactgc tgtcgaataa cctgtcttgg ttttcttagt gtattctaga
    11581 ggaagtccca atttctcaaa gagaagcacg cccaactgct taggcgagtt gacattaaac
    11641 tcctcaccag ccagctcgta aatctcttga gtcagttttt caatgacaag ctcattttca
    11701 gcctgcatct caagcaaggt ctctttcttg accacaatcc cagcaatttc catcttggca
    11761 agaacaaaag ccagaggttg ctccatatca taaagaagct ctaattgccc attttcgctg
    11821 agtttttcaa gtagaacagg ctctgtttct accaaaacag caagtttaca agctaagtgt
    11881 tccaagaatt tctcacgttc aggaatggcc tttttaacac ccttaccgta gaaagtttca
    11941 tcatcaacca agtaagtctg accataaaga ctagcgatgg tcgcaatttc attgtcctcc
    12001 acagtcgaaa ggaggtattt agccaaacgg atgtcaaaag caggcgcctg caaatccaca
    12061 ccaaaacgtt gcaaaagaac tttaaccttc ttaaagtcat aaactctcag agatgttttt
    12121 tctaagaaat ccttgaaaat cgggtcttgc aacagctcaa gcttgtctgt ggcatagagc
    12181 ttatccccac aagaccaggc aaatccaacc aaattatccg tatggtaatt ctcaccaaaa
    12241 agctcaaagt ggaagataga ctcttcactc agcatatctt gactgatttg gtcaacaata
    12301 gtaaaatcca aaccctcagc cacatcagct gacgacacat ttaaagcctg cttgagctgt
    12361 ttgaatccca tctcatcgta aaatttccca agattttcaa catctggacc actatagacc
    12421 aagtcctcta aaccaatcgc aatcggtgcc ttggtatcaa tggtcgctag tgttttagac
    12481 aaaaaggcct gttccttgtc attgatgaga ttttccttca tcttagaagt cttcattcca
    12541 tcaatatttt cataaatccc ctcaagcgaa ccatgctcca gcaagagctt aatacccgtc
    12601 ttttcaccga ctttggtcac cccagggata ttatccgact tatcacccat gagcgccttg
    12661 agatcgataa actgagctgg tgtgaggccc atttcttcca tgaggtaatc tggcgtaaag
    12721 gcctcaaact cagccacacc tttcttggaa atttcaacca ccgtatgctc atccgtcagc
    12781 tgaatcaaat ccttgtcccc actgacaatg gtaatatcaa aaccatcctg ctctgctagc
    12841 ttatccagcg tcccaatgat gtcatccgcc tcatactgag ccagctcata gtgacgaatc
    12901 cccatatgat ccagcaactc acgaatgaaa ggaaattgct cacgaaactc atcaggagtc
    12961 ttggcccgac cacccttata gtccgcatac atctctgtcc ggaaggtcgt ctttcccgca
    13021 tcaaaagcca ccaaaatatg actcggctca acccgctcca acaaatgact caacatcaac
    13081 tgaaaaccat aaatcgcatt ggtatgcaaa ccagccgcat tcttaaaacg gtccaactgc
    13141 tgatacagcg caaaaaacgc ccgaaaagct acagaagacc catcaatcaa taataatttt
    13201 ttcttatcca tacacccatt ataaaggaaa gaatcaaaaa ataccattgg gaagagctag
    13261 agctagtatt tttcaaactt tttccgaata aatagataga gccagagaat ttagtaaacc
    13321 tagatttaaa aatgtgctat aatatagtat attgaatcta taatagtaca ccttgactgc
    13381 taaaatattt ctataaatta atttgacttt cctgatagag ttattcacat cttatttcaa
    13441 ctcactatag aaggaggaat aggaggattc tcagacatcc gggcatcagc ccaactaatg
    13501 atttgattgc taagaaaata ttcagcaatc cagaaatcac ttgtcaattt attcgcgata
    13561 tgctggactt gccagcaaaa aatgtgacca ttttggaggg aagcgatatt cacgtattac
    13621 tctccatgcc ttactcggtg caggattttt ataccagtat agacgtcttg gcggagttgg
    13681 ataacggtac tcaagtaatt attgagattc aagtccatca tcagaatttt ttcatcaatc
    13741 acttgtgggc ttacctgtgc agtcaggtta atcaaaatct tgaaaaaatt cgtcagcgag
    13801 aaggtgatac tcactagagc tacaaacaca tcgctcctgt ttacgccatt gctatcgtgg
    13861 atagtaatta tttctcagat gacctggctt ttcatagctt tagtatgcgc gaagacacaa
    13921 caggtgaggt attggcgatt accaacaatg gacaggaaaa ccatctggtt aagatggcat
    13981 tcttggaatt aaaaaataca gagaaaccag caaagacaag gttcgcaagc catggttgga
    14041 gtttttcggc aacaagccct ttacccagca accgcaacga gccattaccc aagcaaatca
    14101 actgctggac tacaagagct ggtccgagga ggacaggaaa atgtttaatc aactacatat
    14161 gcgagaagaa caagtcttgt tagcacagga ctatgccttg gaaactgcta gggctgaagg
    14221 ccttgaacaa ggattagagc gtgggaaagt tgaaggaagg gcagaaagga aactttttac
    14281 cttcctagac atagtacgcc aaggtcttct gacttctgag gttgccagcc agcaattagg
    14341 tatgtcagta tctgaatttg aggcactgtt gtaaaatggc tccataatat ccatagtggg
    14401 taaatcccct atggatatta tggagcct
//
LOCUS       DBEROT010000047        14151 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.47, whole genome shotgun sequence.
ACCESSION   DBEROT010000047 DBEROT010000000
VERSION     DBEROT010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.47"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..116
                     /locus_tag="ACL8CG_001824"
     CDS             <1..116
                     /locus_tag="ACL8CG_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS1344373.1"
                     /translation="AKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(431..2122)
                     /gene="argS"
                     /locus_tag="ACL8CG_001825"
     CDS             complement(431..2122)
                     /gene="argS"
                     /locus_tag="ACL8CG_001825"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGS1344374.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2258..2704
                     /gene="argR"
                     /locus_tag="ACL8CG_001826"
     CDS             2258..2704
                     /gene="argR"
                     /locus_tag="ACL8CG_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1344375.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2755..5289
                     /gene="mutS"
                     /locus_tag="ACL8CG_001827"
     CDS             2755..5289
                     /gene="mutS"
                     /locus_tag="ACL8CG_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGS1344376.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMENPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5436..7130
                     /gene="patA"
                     /locus_tag="ACL8CG_001828"
     CDS             5436..7130
                     /gene="patA"
                     /locus_tag="ACL8CG_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGS1344377.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7280..7723)
                     /locus_tag="ACL8CG_001829"
                     /pseudo
     CDS             complement(7280..7723)
                     /locus_tag="ACL8CG_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7921..9687
                     /gene="patB"
                     /locus_tag="ACL8CG_001830"
     CDS             7921..9687
                     /gene="patB"
                     /locus_tag="ACL8CG_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGS1344378.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9826..10515
                     /locus_tag="ACL8CG_001831"
     CDS             9826..10515
                     /locus_tag="ACL8CG_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS1344379.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10519..10698
                     /locus_tag="ACL8CG_001832"
     CDS             10519..10698
                     /locus_tag="ACL8CG_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344380.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10685..12034
                     /locus_tag="ACL8CG_001833"
     CDS             10685..12034
                     /locus_tag="ACL8CG_001833"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGS1344381.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12158..13618
                     /gene="gltX"
                     /locus_tag="ACL8CG_001834"
     CDS             12158..13618
                     /gene="gltX"
                     /locus_tag="ACL8CG_001834"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGS1344382.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESYENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            13632..14066
                     /locus_tag="ACL8CG_001835"
     CDS             13632..14066
                     /locus_tag="ACL8CG_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS1344383.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVSELIPYWWGEERASKFNER"
BASE COUNT         4153 a         2724 c         3183 g         4091 t
ORIGIN      
        1 ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct
       61 tcggattacg aatgaatttg attgctggta ttatcaatca tgaactagga ttctagtttt
      121 gcaggaagtc tattatttgg ttaggtgaat tagtgaagtg tttaggcaag tgtctctggt
      181 tacgacgtca tggcctctaa atcgattata tttaggggtc atgactagtg aagcagttag
      241 ctagttcgca tataagcggc tagcgtctaa caattaggaa ctttagttcc aataacttta
      301 agattacgac gttttaggac ataaatcgat catatttatg tcctaaaact agtgaagcgc
      361 ctagccaaag tccgaatagg atttggcgtt agttacttag attgctttgc aatcaagtaa
      421 ctttggcgat ttacatcttc tctggcgctt ctactccaag caagcgaagg gcttctttga
      481 gaacgactgc ggttgcgtag ctgagggcta gacggctgtc gcgttctggg ctttcatcca
      541 agatacgtgt atgtgcatag tatttgttaa aggattgagc caggctaatt gcaaatttag
      601 caatgataga aggttcaaag ttatctgccg cacggttgat aatacgtggg aagtcttgaa
      661 tgagtttaat gatttcccag ctttcagtat cattcaagct atagttgcca gctgtttctg
      721 gtttgaaatc ggctttgcgt aagatagatt ggatacgagc gtaggcatat tgaacgtaag
      781 gtccagtttc accctcgaag gataccatag cttctaggtc gaagtcgtat ccatttgtac
      841 ggtcggtttt gaggtcatag aatttaatgg ctccaacccc aacagcatgt gctacttggt
      901 ctttgttttc tagttcagga tttttagcct cgatttggac cttggcacgg ctaacagcct
      961 ctgcaacagt aggctctagc aagatgacat tccctttacg agtagagagt ttcttccctt
     1021 cttttgtaac caaaccaaaa ggaacgtgag taatgtcgtc actccagtcg tagcccatct
     1081 cttgcaagac agctttgagc tgtttaaagt gggcagattg ttcttgacca acgacataga
     1141 tagatttagc aaattggtat tcgtttttac ggtaaagggc tgcagccaag tcacgtgtga
     1201 tatagagagt tgcaccatca gatttcttga tgagggctgg atgttcaatt ccgtatttct
     1261 caagattgac aacttgggca ccttctgatt caagaagtag tcctttttca gaaagaatgt
     1321 ctacaactgc atccatctta tcattgtaga aggcttctcc gttatagctg tcaaattcaa
     1381 ccttcaattc attgtaaagg cggttaaatt ccactaaact ttcatcgcgg aaccattgcc
     1441 aaagagcgag agcttcctca tctccatttt caagtttacg gaaccattcg cgcgcttctt
     1501 catccaagct agggtcattt tcagcttcag cgttgatgcg gacatagagt ttaaggagtt
     1561 catcgattgg atgagctttt acagcttctt cgtcgcccca ttttttgtag gcaacaatca
     1621 acatcccaaa ttgtttaccc cagtctccca aatggttgac cttgaccgtt tgataaccga
     1681 ttttttggaa aatatgtgac aagctatctc cgataacagt tgaacgcagg tggccaatag
     1741 aaaatggttt agcgatattc ggactagaca tgtcgataac aacattttct tgtttgccaa
     1801 tattttggtc agcatagtgt tctttttcag tggtaacagc ttgcaatact tgagcagaaa
     1861 tggcagattt atcaaggaaa aagttaacgt aaggtcctgt tgcgacaact ttttcaaagg
     1921 cttggctgtt cattttttca gccagttcag ccgcaatcat ttgtggtgct ttacgttcga
     1981 cttttgcaag agaaaaagca gggaaagcaa tgtctcccat ttctgagttt ttaggggttt
     2041 ccagtaactt taaaatagcc tcttggtcca ggctatcaat gatgctagat aattcgctag
     2101 caatcaattc ttttgtattc attaagagct cctttttgga cttttctact attttatcac
     2161 aattttaaag aaagaagaaa aaatttttga aatctcctgt ttttttggta taatatggtt
     2221 ataaatatag ttataaatat gcacgcaaga ggattttatg agaaaaagag atcgtcatca
     2281 gttaataaaa aaaatgatta ctgaggagaa attaagtaca caaaaagaaa ttcaagatcg
     2341 gttggaggcg cacaatgttt gtgtgacgca gacaaccttg tctcgtgatt tgcgcgaaat
     2401 cggcttgacc aaggtcaaga aaaatgatat ggtgtattat gtactagtaa atgagacaga
     2461 aaagattgat ttggtggaat ttttgtctca tcatttagaa ggtgttgcaa gagcagagtt
     2521 taccttggtg cttcatacca aattgggaga agcctctgtt ttggcaaata ttgtagatgt
     2581 aaacaaggat gaatggattt taggaacagt tgctggtgcc aataccttat tggttatttg
     2641 tcgagatcag cacgttgcca aactcatgga agatcgtttg ctagatttga tgaaagataa
     2701 gtaaggtctt gggagttgct ctcaagactt atttttgaaa aggagagaca gaaaatggcg
     2761 atagaaaagc tatcacccgg catgcaacag tatgtggata ttaaaaagca atatccagat
     2821 gcttttttgc tctttcggat gggtgatttt tatgaattat tttatgagga tgcggtcaat
     2881 gctgcgcaga ttctggaaat ttccttaacg agtcgcaaca agaatgccga caatccgatc
     2941 cctatggcgg gtgttcccta tcattctgcc caacagtata tcgatgtctt gattgagcag
     3001 ggttataagg tggctatcgc agagcagatg gaaaatccta aacaagcagt tggggttgtt
     3061 aaacgagagg ttgttcaggt cattacgcca gggacagtgg tcgatagcag taagccggac
     3121 agtcagaata attttttggt tgccatagac cgcgaaggca atcaatttgg cctagcttat
     3181 atggatttgg tgacgggtga cttttatgtg acaggtcttt tggatttcac gctggtttgt
     3241 ggggaaatcc gtaacctcaa ggctcgagaa gtggtgttgg gttatgactt gtctgaggaa
     3301 gaagaacaaa tcctcagccg ccagatgaat ctggtactct cttatgaaaa agaaagcttt
     3361 gaagaccttc atttattgga tttgcgattg gcaacggtgg agcaaacggc atctagtaag
     3421 ctgctccagt atgttcatcg gactcagatg agggaattga accacctcaa acctgttatc
     3481 cgatacgaaa ttaaggattt cttgcagatg gattatgcga ccaaggctag tctggatttg
     3541 gttgagaatg ctcgctcagg taagaaacaa ggcagtcttt tctggctttt ggatgaaacc
     3601 aaaacggcta tggggatgcg tctcttgcgt tcttggattc atcgcccctt gattgataag
     3661 gaacgaatcg tccaacgtca agaagtagtg caggtctttc tcgaccattt ctttgagcgt
     3721 agtgacttga cagacagtct caagggtgtt tatgacattg agcgcttggc tagtcgtgtt
     3781 tcttttggca aaaccaatcc aaaggatctc ttgcagttgg cgactacctt gtctagtgtg
     3841 ccacggattc gtgcgatttt agaagggatg gagcaaccta ctctagccta tctcatcgca
     3901 caactggatg caatccctga gttggagagt ttgattagcg cagcgattgc tcctgaagct
     3961 cctcatgtga ttacagatgg gggaattatc cggactggat ttgatgagac tttagacaag
     4021 tatcgttgcg ttctcagaga agggactagc tggattgctg agattgaggc taaggagcga
     4081 gaaaactctg gtatcagcac gctcaagatt gactacaata aaaaggatgg ctactatttt
     4141 catgtgacca attcgcaact aggaaatgtg ccagcccact ttttccgcaa ggcgacgctg
     4201 aaaaactcag aacgctttgg aaccgaagaa ttagcccgta tcgagggaga tatgcttgag
     4261 gcgcgtgaga agtcagccaa cctcgaatac gaaatattta tgcgcattcg tgaagaggtc
     4321 ggcaagtaca tccagcgttt acaagctcta gcccaaggaa ttgcgacggt tgatgtctta
     4381 cagagtctgg cggttgtggc tgaaacccag catttgattc gacctgagtt tggtgacgat
     4441 tcacaaattg atatccggaa agggcgccat gctgtcgttg aaaaggttat gggggctcag
     4501 acctatattc caaatacgat tcagatggca gaagatacca gtattcaact gattacaggg
     4561 ccaaacatga gtgggaagtc tacctatatg cgtcagttag ccatgacggc ggttatggcc
     4621 cagctgggtt cctatgttcc tgctgaaagc gcccatttac cgatttttga tgcgattttt
     4681 acccgtatcg gagcagcaga tgacttggtt tcgggtcagt cgacctttat ggtggagatg
     4741 atggaggcca ataatgccat ttcgcatgcg accaagaact ctctcattct ctttgatgaa
     4801 ttgggacgtg gaactgcaac ttatgacggg atggctcttg ctcagtccat catcgaatat
     4861 atccatgagc acatcggagc taagaccctc tttgcgaccc actaccatga gttgactagt
     4921 ctggagtcta gtttacaaca cttggtcaat gtccacgtgg caactctgga gcaggatggg
     4981 caggttacct tccttcacaa gattgaaccg ggaccagctg ataaatccta cggtatccat
     5041 gttgccaaga ttgctggctt gccagcagac cttttagcaa gggcggataa gattttgact
     5101 cagctagaga atcaaggaac agagagtcct cctcccatga gacaaactag tgctgtcact
     5161 gaacagattt cactctttga tagggcagaa gagcatccta tcctagcaga attagctaaa
     5221 ctggatgtgt ataatatgac acctatgcag gttatgaatg tcttagtaga gttaaaacag
     5281 aaactataaa accaagactc actagttaat ctagctgtat caaggagact tctttgacaa
     5341 ttctccactt ttttgctaga ataacatcac acaaacagaa tgaaaaggag ctgacgcatt
     5401 gtcgctccct tttgtctatt ttttaaggag aaagtatgct gattcagaaa ataaaaacct
     5461 acaagtggca ggccctggct tcgctcctga tgacaggctt gatggttgct agttcacttc
     5521 tgcaaccgcg ttatctgcag gaagtcttag gcgccctcct tactgggaaa tatgaagcta
     5581 tttatagtat cggggcttgg ttgattggtg tggccgtagt cggtctagtt gctggtggac
     5641 tcaatgttgt cctcgcagcc tatattgccc aaggagtttc atccgacctt cgggaggatg
     5701 ccttccgtaa aattcaaacc ttttcttatg ctgatattga acaatttaat gcgggaaatc
     5761 tagtcgttcg aatgacaaat gatatcaacc agattcagaa cgttgtcatg atgaccttcc
     5821 aaattctttt cagacttccc ctcttgttca tcggttcgtt tatcctagcg gttcaaacct
     5881 taccttctct gtggtgggtg attgttctca tggtagtctt gatttttggt ttgactgctg
     5941 tcatgatggg aatgatgggg cctcgttttg ccaagtttca aacccttctt gagcgcatca
     6001 atgccattgc caaggaaaat ttacgtggcg ttcgtgtggt caagtccttt gtccaagaaa
     6061 aagagcaatt tgctaagttt acagaggtct cagacgagct tcttggtcaa aacctttaca
     6121 ttggttatgc cttttcagta gtggaaccct ttatgatgtt ggttggttac ggggcggtct
     6181 tcctctctat ttggctggtc gcgggaatgg ttcagtcgga tccgtctgtt gttggttcca
     6241 tcgcttcttt tgttaattac ctaagccaga ttatctttac cattgttatg gttggatttt
     6301 tgggaaattc tgtcagccgt gccatgattt ccatgcgtcg tattcgagaa attcttgacg
     6361 cagagccagc tatgaccttc aaggatatcc cagatgaaga gttggttgga agccttagct
     6421 ttgaaaatgt gacctttacc tatccaatgg acaaggaacc gatgctgaaa gatgtgagct
     6481 ttactattga acctggtcaa atggttggtg tagttggagc gactggtgca ggaaagtcaa
     6541 ccttggctca attgattcca cgtctctttg atccacagga aggggctatc aaaatcggag
     6601 gtaaggatat tcgagaagtg agtgaaggga ccctgcgtaa aacagtttcc atcgttctcc
     6661 aacgtgccat tctttttagt ggaacgattg cagataactt gagacagggg aagggaaatg
     6721 ctactctatt tgaaatggag cgcgcagcca atattgccca ggctagtgaa ttcattcatc
     6781 gtatggagaa aacctttgaa agtccagttg aagaacgggg aaccaatttc tctggtggac
     6841 aaaaacaaag gatgtcgatt gcgcgtggga ttgtcagcaa tccacgtatt ctgatttttg
     6901 atgattcgac ctcagccttg gatgccaaat cagagcgctt ggtgcaagaa gctttgaata
     6961 aggacttgaa ggggacgaca actattatta ttgctcaaaa aattagctcg gttgtccatg
     7021 cagacaagat cttggttcta aatcaaggac gattgattgg tcaaggcacg catgcagact
     7081 tggttgccaa caatgccgtt taccgtgaaa tctatgaaac acagaaatga aagacaaact
     7141 ataagaaaag tcaatagttt tatctaaact atttcttatt tcaatttgat gatttggcga
     7201 tgattttaga gcacggcaaa aagcccttga aaaagtccat tttttcaaag gtaatcctgt
     7261 gttaatttca gaaattacat cactttttgt tcgtcaaatg gcagctcttt tttaggatat
     7321 aaaacagggt tcggataagt ttttttgcaa ggtggatgat ggctacattg taatgttttc
     7381 cttgttctaa cttagtctta agataggtct taaaagcagg tgaaaagcga gggcatgctt
     7441 tggcagcttg tatgagtacc taccgcagat gaggggaacc ccgtttgacc attcttccag
     7501 ctaaatcaat ctgacctgac tgataaatag aagaatccag tccagcgaaa gcttgtaatt
     7561 gagcaggatt atcaaaggca tgaatatttc gaatctcggc taaaatgacc gcccctaaac
     7621 gattctcaat cccagtaacc gtcgtgatga ccgagttgaa ctcagccatc aagtcattga
     7681 cacatgtttc cgccttgtca atgagcctct tgtaatgttt gatgttttca ttacacgaga
     7741 taaaacgtct atgcgttatc aaactcatta ccaattaaaa caaaaagctg tggttagatc
     7801 ctttcggaaa ttgtcaagcg attggaggaa atgaactaat ccacagcggc ttattccaag
     7861 tataccactt gggctttggc agtagctaac tgcgctaaat ataatataag gaggagtaaa
     7921 atgaagacag ttcaattttt ttggcattat tttaaggtct acaagttctc atttgtagtt
     7981 gtcatcctga tgattgttct ggcgactttt gcccaagccc tctttccagt cttttctgga
     8041 caagcggtga cgcagctagc caatttagtt caagcttatc aaaatggcaa tccagaactt
     8101 gtatggcaaa gcctatcagg aatcatggtc aatcttggcc tgctggtttt ggttctattt
     8161 atctctagtg taatatacat gtgtctcatg acgcgcgtga ttgcagaatc gaccaacgag
     8221 atgcgcaaag gcctctttgg taagcttgct cagttgacgg tttctttctt tgaccgtcga
     8281 caagatggcg atatcctgtc tcattttacc agtgatttgg ataatatcct ccaagccttt
     8341 aacgaaagct tgattcaggt catgagcaat attgttttat acattggtct gattcttgtc
     8401 atgttttcga gaaatgtgac gctggctctc atcaccattg ccagcacccc attggctttc
     8461 cttatgctga ttttcatcgt gaaaatggca cgcaaataca ccaacctcca gcagaaagag
     8521 gtagggaagc tcaacgccta tatggatgag agcatctcag gccaaaaagc cgtgattgtg
     8581 caaggaattc aagaggatat gatggcagga tttcttgaac aaaatgagcg cgtgcgcaag
     8641 gcaaccttta aaggaagaat gttctcagga attcttttcc ctgtcatgaa tgggatgagc
     8701 ctgattaata cagccatcgt catctttgct ggttcggctg tacttttgaa tgataagtct
     8761 attgaaacaa gtacagccct aggtttgatt gttatgtttg cacaattttc acagcagtac
     8821 taccagccta ttatccaagt tgcagcgagt tggggaagcc ttcagttggc ctttactgga
     8881 gctgaacgaa ttcaggaaat gtttgatgca gaggaggaaa tccgacctga aaaggctcca
     8941 accttcacta agttgcaaga aagtgttgaa atcagtcata tcgatttttc atacttgcct
     9001 gataaaccta ttttgaaaga tgtcagcatt tctgccccta aaggccagat gacagcagtt
     9061 gttgggccga caggttcagg aaaaacgact attatgaacc tcatcaatcg cttttatgat
     9121 gttgatgctg gtggtattta ttttgatggt aaagacattc gtggctatga cttagatagt
     9181 cttagaagca aggtgggaat tgtattgcaa gattcggtct tgtttagcgg aacgattaga
     9241 gacaatatcc gatttggtgt gccagatgct agtcaggaaa tggttgaggt agcagcaaaa
     9301 gcaacccaca ttcacgacta tatcgaaagt ttgcctgata agtacgatac tcttattgat
     9361 gatgaccaga gcatcttttc aacagggcag aagcaattga tttcaatcgc tcgaaccctg
     9421 atgacagatc cagaagttct cattctcgat gaagcaactt caaacgtaga tacggtgaca
     9481 gaaagcaaga ttcagcatgc catggaggtg gttgtagcag gtagaactag tttcgtcatt
     9541 gcccaccgct tgaaaaccat tctcaatgca gatcagatta ttgtccttaa agatggagaa
     9601 gtcattgaac gtggtaacca ccatgaactt ttgaagctag gtggctttta ttcagaactc
     9661 tatcacaatc aatttgtttt cgaataagaa agaagttgtc ctatgtgggc agctttttct
     9721 tgtccataaa aaatgtttat cacagcctta aaaaaaacat attagacgaa agtcattttg
     9781 agtgatatga taggactatc gttagcattc gaaaggagag gcatcatggc tagaacggtt
     9841 gtaggagttg ctgcaaatct atgtcccgta gacgcagaag gcaaaatcat tcattcatct
     9901 gtatcttgta gattcgcaga gatcattcgt caagtcggtg gtctcccttt agtcattcct
     9961 gttggtgatg agtcagttgt acgtgattat gtggaaatga ttgacaaact cattttgaca
    10021 ggaggccaaa atgttcatcc tcagttttat ggagagaaaa agaccgtcga aagcgatgat
    10081 tacaatctgg tccgtgacga atttgaattg gcactcttga aggaagcgct tcgtcagaat
    10141 aaaccaatta tggcaatctg tcgcggtgtc caacttgtca atgttgcctt tggtggaacc
    10201 ctcaatcaag aaatcgaagg tcactggcaa ggactacctt tcgggacatc tcactctatt
    10261 gagacagtag aaggaagcgt ggtggctaag ctatttggga aagaaagtca ggtcaactca
    10321 gtccatcgtc aaagcattaa agatttggca cctaatttcc gtgtaactgc tattgattca
    10381 agagaccaaa ctattgaagc gattgagtct atcgacgagc accgcattat cggtttacag
    10441 tggcatccag agtttctggt taatgaagaa gatggcaatt tagaattatt tgagtattta
    10501 ttgaatgaac tgtaacgatt ggaacatctg gtcgttcttt cttttatttt ttcaaaattt
    10561 ttagaatgtg gcattttacg caaacgtttg aattctgata aaaattggag aaattcgaca
    10621 aaaaaacttg aaaaaaacga aggtaagcgt tatgatagaa aagaagaaat attggaggaa
    10681 gaacatgtca catattaaat ttgattattc aaaagtttta gacaaatttg ttgcaccaca
    10741 tgaagtggaa tacatgcaat cacaagtaac agcagcagat gaattgatcc gtaaaggaac
    10801 tggtgctggt agcgacttct tgggatggtt ggaccttcct gaaaaatacg accgcgaaga
    10861 atttgaccgc atcttgaaag ctgctgagca aatcaagtca gacagcgatg ttttggttgt
    10921 gatcggtatt ggtggatctt accttggtgc aaaagcagca atcgacttct tgaatcacca
    10981 ttttgctaac ttgcaaacaa aagaagaacg caaagctcca caaatccttt acgcaggaaa
    11041 ctcaatctca tctacttacc ttgctgactt ggtagagtat gttgcagaca aggacttctc
    11101 agtaaacgta atttctaaat caggtacaac aactgaacca gcgattgctt tccgtgtctt
    11161 taaagaactc ttggttaaga aatacggtca agaagaagct aacaaacgta tctatgcaac
    11221 aactgaccgc caaaagggtg ctgttaaggt tgaagcagac gctaacggtt ggggaacatt
    11281 tgttgttcca gatgatatcg gcggacgctt ctcagtattg acagccgttg gtttgcttcc
    11341 aatcgcagca tcaggagctg acatcaaagc tcttatggaa ggtgcgaatg cagctcgcaa
    11401 agactacact tcagacaaaa tctctgaaaa cgaagcttac caatacgcag ccgttcgtaa
    11461 catcctttat cgtaaaggct atgcaactga gatcttggta aactatgagc catcacttca
    11521 atacttctca gaatggtgga aacaattggc tggtgaatca gaaggaaaag accaaaaagg
    11581 tatctaccca acttcagcca acttctcaac tgacttgcac tcacttggtc aatttatcca
    11641 agaaggaact cgtatcatgt ttgaaacagt tgtccgtgtt gacaaacctc gtaaaaacgt
    11701 gcttattcct actttggaag aagaccttga cggacttggt taccttcaag gaaaagacgt
    11761 tgactttgta aacaaaaaag caactgacgg tgttcttctt gcccacacag atggtgatgt
    11821 accaaacatg tatgtgactc ttccagagca agacgctttc actcttggtt acactatcta
    11881 cttcttcgaa ttggcaattg ccctttcagg ttacttgaat gctatcaacc catttgacca
    11941 accaggtgtt gaagcttata aacgtaacat gtttgccctt cttggaaaac caggatttga
    12001 agaattgagc aaagaactta acgcacgtct ataatagaag aaaagagtgg tttgcccact
    12061 ctttttactc tctttatcca tagaaattgg actcagccaa gacttgtgat ataatataga
    12121 aagcaaaaag gcagacgcct agataatagg agaaactatg tcaaaagata tccgcgtacg
    12181 ttacgcacca agtccaacag gactactaca catcggaaat gctcgtacag cattgtttaa
    12241 ttacttgtat gcgcgccatc atggtggaac atttctcatc cgtatcgaag atactgaccg
    12301 taaacgccat gtcgaggatg gtgaacgttc acaacttgaa aaccttcgct ggttaggcat
    12361 ggattgggat gaaagtccag aatcatatga gaattatcgc cagtctgagc gtttagactt
    12421 gtatcaaaaa tacattgacc aactattagc tgaaggaaaa gcctataaat cttacgttac
    12481 agaagaagag ttggcagctg aacgcgaacg ccaagaagta gctggcgaaa caccacgcta
    12541 catcaatgaa taccttggta tgagtgaaga agaaaaagca gcttacatcg cagaacgtga
    12601 agcagcaggg atcatcccaa ctgttcgttt ggctgtcaat gagtcaggta tctacaagtg
    12661 gcatgatatg gtcaaaggcg atatcgaatt tgaaggtggc aatatcggtg gtgactggat
    12721 tatccaaaag aaagacggtt acccaactta caactttgcc gttgccatcg atgaccatga
    12781 tatgcaaatc tcccatgtta tccgtggaga cgaccatatt gctaacacac caaaacagct
    12841 catggtttat gaagcacttg gttgggaagc tccagagttt ggtcacatga ccttgattat
    12901 caactctgag actggtaaga agttatctaa acgtgatact aatacacttc aatttatcga
    12961 agattaccga aagaaaggtt accttccaga agcagtcttt aattttattg ctcttcttgg
    13021 ttggaaccca ggtggtgaag atgagatttt ctctcgtgaa gaactcatta aactttttga
    13081 tgaaaaccgc ctcagcaagt caccagcagc ctttgatcag aaaaaattag actggatgag
    13141 caatgattat atcaagaatg cagaccttga aaccatcttt gaaatggcaa aaccattctt
    13201 agaggaagca ggccgtttga ctgacaaggc tgaaaaatta gttgagctct ataaaccaca
    13261 aatgaaatca gtagatgaga ttatcccatt gacagatctt ttcttctcag atttcccaga
    13321 attgacagaa gcagagcgcg aagtcatgac gggtgaaaca gttccaacag ttcttgaagc
    13381 attcaaagca aaacttgaag cgatgacaga tgatgaattt gtgacagaaa atatcttccc
    13441 acaaattaaa gcagtccaaa aagaaacagg tattaaaggg aaaaatcttt tcatgcctat
    13501 tcgtatcgca gtttcaggcg aaatgcatgg gccagaatta ccagatacaa ttttcttgct
    13561 tggacgtgaa aaatcaattc agcatatcga aaacattcta aaagaaatct ctaaataaag
    13621 aggatacaat aatggacatc tgggaaaaga tgtacgaaga agcacagaaa ctatacaatc
    13681 cacatgaagt atcagacttt gtttatgcca atcatgttgt agctgcagta gaagcaggag
    13741 atggacaaat atttacagga ttctgtatgg agggaacctg tggtgttttc catctctgcg
    13801 cagaacgggc ggccctcttc aatatgtacc aattttcagg acaaactaag gttaagaaag
    13861 tattagcctt tcgagataaa ccaccttatg gtggaagttc agccatgcct tgcggtgctt
    13921 gtagagaatt ccttttagag cttaatgctg aaaataaaga tgcagaattc atgatggact
    13981 ataatataag aaaaacagtt aaagtctcag aactaatccc ttattggtgg ggagaagaac
    14041 gtgcttctaa gtttaatgag cgatagaaga gtcagtataa ttctggctct ttttactata
    14101 aattgaaaaa ataaaaaaaa ttagaaaaag tagttgacaa agtttgaaaa g
//
LOCUS       DBEROT010000048        13813 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.48, whole genome shotgun sequence.
ACCESSION   DBEROT010000048 DBEROT010000000
VERSION     DBEROT010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.48"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(56..964)
                     /locus_tag="ACL8CG_001836"
     CDS             complement(56..964)
                     /locus_tag="ACL8CG_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS1344384.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMKKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            1028..1297
                     /locus_tag="ACL8CG_001837"
     CDS             1028..1297
                     /locus_tag="ACL8CG_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGS1344385.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            1297..1677
                     /locus_tag="ACL8CG_001838"
     CDS             1297..1677
                     /locus_tag="ACL8CG_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS1344386.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            1766..1993
                     /locus_tag="ACL8CG_001839"
     CDS             1766..1993
                     /locus_tag="ACL8CG_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344387.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(2033..2758)
                     /locus_tag="ACL8CG_001840"
     CDS             complement(2033..2758)
                     /locus_tag="ACL8CG_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGS1344388.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            2920..4761
                     /gene="typA"
                     /locus_tag="ACL8CG_001841"
     CDS             2920..4761
                     /gene="typA"
                     /locus_tag="ACL8CG_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGS1344389.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            4781..5035
                     /locus_tag="ACL8CG_001842"
     CDS             4781..5035
                     /locus_tag="ACL8CG_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGS1344390.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            5399..5698
                     /locus_tag="ACL8CG_001843"
     CDS             5399..5698
                     /locus_tag="ACL8CG_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS1344391.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            5769..7790
                     /locus_tag="ACL8CG_001844"
     CDS             5769..7790
                     /locus_tag="ACL8CG_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS1344392.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            7792..8433
                     /locus_tag="ACL8CG_001845"
     CDS             7792..8433
                     /locus_tag="ACL8CG_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344393.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLSLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            8537..9889
                     /gene="murD"
                     /locus_tag="ACL8CG_001846"
     CDS             8537..9889
                     /gene="murD"
                     /locus_tag="ACL8CG_001846"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGS1344394.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVAFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            9893..10951
                     /locus_tag="ACL8CG_001847"
     CDS             9893..10951
                     /locus_tag="ACL8CG_001847"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGS1344395.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGNKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            10961..12127
                     /gene="divIB"
                     /locus_tag="ACL8CG_001848"
     CDS             10961..12127
                     /gene="divIB"
                     /locus_tag="ACL8CG_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGS1344396.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            12393..13094
                     /gene="pyrF"
                     /locus_tag="ACL8CG_001849"
     CDS             12393..13094
                     /gene="pyrF"
                     /locus_tag="ACL8CG_001849"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGS1344397.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPIIQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            13128..13760
                     /gene="pyrE"
                     /locus_tag="ACL8CG_001850"
     CDS             13128..13760
                     /gene="pyrE"
                     /locus_tag="ACL8CG_001850"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGS1344398.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMNLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
BASE COUNT         4182 a         2529 c         3072 g         4030 t
ORIGIN      
        1 aaaaagaacc aatgtgcagg ttgttgctag cctacatatt ggttcttatc atttctcaac
       61 tatcaaactg aacttcttct agtagatagt caataaagcg ttcgcccatc ttagataggc
      121 tggttttctc atgctggata tagaccagct caatcgggtc atcaatatcc agtgggatag
      181 aaacgatatt gtctccgttt aggttgctgt tcaaaatccc tgtcgcaatg gtataaccat
      241 ccaaaccaat caagagatta aagagggtgg cacggtcact gaccacaatg gatttcttgt
      301 ggtgttcttg agaaagaatc tcttctgaaa agtagaagga gttgtgcgtc ccttggtcat
      361 agctgaggta agggaaattc tccaaatcag acagtttcac cttgtctttc tttgccagag
      421 ggttggtctt gctgacaaag atatgcggtt gcgctgtgaa gagatggtgg gctagcaggt
      481 gattgtcatc cagcatcttg gttaaaacat cacggttgta actgtttaag aagaggaccc
      541 cgacctcact gcggaagttc ttgacgtcgt cgataatctc ccaagtccga gtttcacgaa
      601 ggaagagttc gtatttcttc atatcgcttt tcttgagcaa agagacaaag gcattgacca
      661 caaaggcata gtgttgagac gaaacgctaa agagttcgcg gtgggcaaca ggatttttat
      721 agcgttcctc cagaagctgg gtctgctcga caacctgacg ggcataagag agaaactcca
      781 tcccatcacg ggtcaaggta atacccttgg gattgcggat aaagatttca atgcccattt
      841 cattttccaa atctcgcact gcattggaga gactgggctg agtgataaag agttgcttgg
      901 ctgcctcatt catagagcca gtttcgacga ttttgataat ataatgtaat tgttgaattc
      961 tcatgttttt attgtaccac acttgcctta gaatcgccaa agaagatagg aaaataagga
     1021 gcattgtgtg agtctcttct tgaaaaaaac acaaaatttt gctagaatga gtcttatgaa
     1081 aacattctat gatgtgcagc aattcctcaa acgatttggt attattgttt acatgggaaa
     1141 acgcttatat gatattgaac tgatgaagtt ggaactatct cggatttacg atgcagggtt
     1201 gatggataaa ttagactatc tagaggcaga agcagttctt cgcagagagc acaaggtaga
     1261 attggattat attgagaaaa atggagaaaa gaactaatgg ttacttggat tttgtgggca
     1321 cttatactag caatgttggc gtggatgggc tttaactatc ttcgtattcg tcgtgcggct
     1381 aaaattgtgg acaatgagga gtttgaagcc ttgattcgta cgggtcaatt gattgatttg
     1441 cgcgacccag cagaattcca cagaaaacat atccttggtg cacgcaatat tccttcaagt
     1501 cagttgaaaa ctagtcttgc agcccttcgt aaagataaac ctgtccttct ctacgagaac
     1561 caacgtgcgc aacgagttac aaatgcagct ctttacttga aaaaacaagg tttttctgag
     1621 atttatatcc tttcttatgg cttggattct tggaaaggga aagtgaagac tagctaacct
     1681 tatttccaaa ttagtcgaat gataggatga agctattgtt ttatagtata attaatttgt
     1741 ataaaattta aggagttctt agaacataaa agaaaagaag aaaaatccac tttttgtggg
     1801 tatcttgtcg attattcttg gtttgttatt tccaattgta ggcctgattt tgggtatcat
     1861 aggattggtc ttggctattt cataccaaaa agagtcacaa ttagactata aaatagaaaa
     1921 gattcttaat atcttaggaa ttgtgatttc tgtagttaac tggattgtag caatcgcctt
     1981 aatttttcgg taaataaaag aaaaaagctt tagttttaaa gcttttttta ttttatcgac
     2041 tcatctctaa atagttttta atgatttgta actctttttg gttcaaaggg cggtagttac
     2101 cttctgctaa atctgggttc aatgtgaagt ccccaaattg gattctcttg aggctagtta
     2161 ccttaacacc aaccgagagg aacattttct tgatttgatg aaattttcct tctgaaatgg
     2221 tgatagaggc ttgactgagg gaaggacttg cagatagaat ctctagtttt gcgggtttac
     2281 agacagtacc atctaaaaag acaattccct tttgaaaggc ttggatatgg tcaggtgtta
     2341 gaagtccatt aacctcaact tgataagtct tatcgacatg atattgggga tggaggagtt
     2401 ggaagcccaa gggaccgtta tcggtcaaga gaaggagtcc tgttgtatct cggtccagtc
     2461 ggccgacggc atagagcttg tcagactgga tgtcagatgg aagcaggtcc atgacggtcg
     2521 gaagttcctt gtctttgttg gctgtaacga caccagcagg tttatgaagc ataagatagg
     2581 tgtgttcata gccttgaatg attcgatcct gaaaaaggag ttcttgtagt cctgtatcga
     2641 tattttgagc tagggagcgg gctgggcaac catcgactag aatttcccct ctgaggagtg
     2701 cttgcttcat ggcctttcgg ctaacttttt cttgggctaa taaattatct aaacgcatac
     2761 tgtgcctatc ttatcataag tcgcttgctt tgaaaaggct tgacgtgaaa agaaaagcgg
     2821 agtgaaaaca tttacacttg cttgagttat gttatttatt tgaaattatg gtataatcgt
     2881 tcagttagaa aataaatttt gaatattata gaggaaatca tgacaaaatt aagagaagat
     2941 atccgtaaca ttgcgattat cgcccacgtt gaccacggta aaacaaccct ggttgacgaa
     3001 ttattgaaac aatcagaaac gcttgatgca cgtactgaat tggcagagcg tgctatggac
     3061 tcaaacgata tcgaaaaaga gcgtgggatt accatccttg ctaaaaatac tgccgttgct
     3121 tacaacggaa ctcgtatcaa cattatggac acaccaggac acgcggactt cggtggagaa
     3181 gttgagcgta tcatgaaaat ggttgacggt gttgtcttgg tcgtagatgc ctatgaagga
     3241 accatgccac aaactcgttt cgtattgaaa aaagccttgg aacaagacct tgtcccaatc
     3301 gtggttgtta acaaaatcga taagccatca gctcgtccag cagaagtagt ggatgaagtc
     3361 ttggaacttt tcatcgagct tggtgcagat gacgaccagc ttgatttccc agtggtttat
     3421 gcttcagcga tcaacggaac ttcttcattg tcagatgatc cagctgacca agaagcgact
     3481 atggcaccaa tctttgacac gattatcgac catatcccag ctccagtaga taactcagat
     3541 gagcctttgc agttccaagt gtcacttttg gactacaatg actttgttgg acgtatcggt
     3601 atcggtcgtg tcttccgtgg tacagttaag gttggggacc aggttaccct ttctaaactt
     3661 gacggtacaa ctaaaaactt ccgtgttaca aaactcttcg gtttctttgg tttggaacgt
     3721 cgtgaaatcc aagaagccaa agcgggtgac ttgattgccg tttcaggtat ggaagacatc
     3781 tttgtcggtg aaaccatcac tccgacagat gcagtagaag ctcttccaat cctacacatc
     3841 gatgagccaa ctcttcaaat gactttcttg gtcaacaact caccatttgc tggtaaagaa
     3901 ggtaaatggg taacttctcg taaggtggaa gaacgcttgc aggcagaatt gcaaacagac
     3961 gtttcccttc gtgttgaccc aactgattca ccagataaat ggactgtttc aggacgtgga
     4021 gaattgcact tgtcaatcct tatcgaaaca atgcgtcgtg agggctatga acttcaagta
     4081 tctcgtccag aagttatcgt aaaagaaatc gacggtgtta aatgtgaacc atttgaacgt
     4141 gtacaaatcg acactccaga agaataccaa gggtctgtta tccaaagcct ttctgaacgt
     4201 aaaggtgaaa tgttggatat gatttcaact ggtaatggtc aaactcgttt ggtcttcctt
     4261 gttccagcgc gtggtttgat tggatactca actgagttct tgtcaatgac tcgtggttac
     4321 ggtatcatga accatacctt cgaccaatac ttgccattga ttccagggga aattggtgga
     4381 cgtcaccgtg gtgcccttgt ttctatcgat gctggtaagg ctacaactta ctcaatcatg
     4441 tctatcgaag aacgtggtac gatctttgtc aacccaggta ctgaggttta tgaaggaatg
     4501 atcatcggtg aaaactctcg tgaaaatgac ttgacagtta acatcacgaa ggcaaaacaa
     4561 atgaccaacg ttcgttcagc tactaaggac caaacagctg ttatcaagac gcctcgtatc
     4621 ttgacacttg aagagtctct tgagttcttg aacgacgatg agtacatgga agtaacgcct
     4681 gagtctatcc gtttgcgtaa acaaatcctt aacaaagcag agcgtgagaa agctaacaag
     4741 aagaaaaaat cagctgaata agagctagaa agagagaaag atggtctatt tagtcctagg
     4801 aattttactg ctcctactct atgtatttgc gacaccagaa agcattaaag ggactgtcaa
     4861 tatcgtcgct atggtatgta ttttagtggc actcttgatt ttattggttc tatcttttct
     4921 gaaaattttt caattaccaa cagaaatatt cctagcaata gccatgttga tcctagctta
     4981 ctttagtgtt agagacatca cactcatgcc agtcaaaaaa agtaaaagaa gataaaaaga
     5041 gagttttggc tctctttttt gctaggaatt ttacaagatt gcaatttatt tttgagttat
     5101 caccatctct tttgtttgga taatatgaat gggaaaaact tgaataaaat tctttaatgg
     5161 catctatttt atatttggtt agtactggtt gcatattatt ttgaaataaa actactatat
     5221 aatattattc atagaggcaa tgtagtaaaa tatctaaaaa attcgatttt ttccttgaca
     5281 acaaataata aaaatgatat ttttatcaca taagaaagcg gtttcaacaa aagagagagg
     5341 agggtttatt ttgttgcatt gttgctcaag gtgtgctttt tttgaaagaa aaaataaaat
     5401 gaaaacgaaa aaacatagat tacttgctct agctcttatt tcaagtttta cattattggg
     5461 agctgcatca gctgctgtac aatatccaga tggaggagta tggacgtatg gagaaggttc
     5521 aggaggtggt tgggcttttt caaattacta tcatggtaaa aaatatcatt attcttctct
     5581 tgtaagtaga tggaatagtc attcagataa aggagaagct tctgctggaa aaacctccta
     5641 tgcatggatt tggactaaat ggggagaaca agtagcattt tactgtgatt atgactaatc
     5701 gttcattgat ttaaatcgtt ccccttgtaa gaaattacag ggggaatttt gtttacaagg
     5761 agtctactat gaagaaacta ttcatattat tatcaacttt ttttctcagc ttcttccttg
     5821 cttggattat tgtcttacgt gcgccacaat atttatatgc aagctatgat tccgtttctt
     5881 tacttcgtgt caaaaaagat actcaggaac cgacgcgtga ggtatttgaa caggaattgg
     5941 agaattttgc aaactcagaa cagagtttaa tagctagaag aattgtagag ccgagtaagg
     6001 atgggacgac tcactttact tatgcaactt atggtcaggg aactttacca aaagaattcc
     6061 aagaagctag ccaagaaagt cgtgaacgta gtgatccgct aaatagttat ctccttttgt
     6121 caggctcctt gacgaaagaa aagcttgccg ataaattagg agatttgggt tataaagcaa
     6181 gtgctgaccg aaagataccg ccctattttc ttgcttttcg aatattacta aatcccctta
     6241 ttttaattag tttagcaata tttggcttat ctttctttgc tttagtgatt atcactcgga
     6301 ttaaggaaat gagagcagca ggtataaaac tcttttctgg tcagactctc ttatccatca
     6361 tggggcattc tttatctact gatatcaaat ggctccttct atcagccctc ctttccttcc
     6421 taggtggggg agtcgttctt tttagtcaag gtttgtttta tcctatcttg ttagccacct
     6481 atggttttgg gattagtttc tatctgttgt ttttattggc gatttcaatt ttactaatgc
     6541 ttctttatct aatgagtttg agttacaaag cattagttcc cgttattaag gggagattac
     6601 cccttaaacg cctgatgatt ttaaccctat tgtgtcagtt ggttgctgtc tttacagtag
     6661 gctacgctgt taagacaggt ttgatgtctt accaacgatt gaaagaactt gaaatttcaa
     6721 aacaagcatg gcaggataga gcagactatt atcaaatttc ttttggctta ggtgatagag
     6781 gaaaagatac agaaaatcag agcaagtggt atgcctttgc caaggaagca atcgaagaag
     6841 aacaagctct ttatgtaaag gataatctgc tccattttgc caatccacaa ggaaaaaatg
     6901 aacagggaga gacactggat acctatagtc cagatgctaa tacgctctat gttagtccca
     6961 gttatttgga caaggaaaag gtcgtggtag atgctgagac caaacagaag ttagcccatc
     7021 tccaaaaagg tgagtttatc ctcttgctcc cagaacattt gcgctctcga gaagcagaac
     7081 ttaagaaagt ttttgaagaa agattgagtt attatggaaa atctggtgag gaggcaagtg
     7141 ctcctttgga ttatgagatg aaagcgcacg ttagttatct ttcaatggga gaaaagcggt
     7201 ttgtttataa taacggtgag aatcccgtat ccactcagta tttgactgat ccgattttag
     7261 tggtattcac gccgacttct acaggtgata gttttatatc cttatctagt tggtctatca
     7321 atgctggaaa acaactcttt atcaaaggat atgagagtgg gctagaactc ttgaagaaag
     7381 ctggaattta tgagcaagta tcctatctta aagaaggaag aagtgtttat ctaactcgtt
     7441 ataatgaagt tcaaactgaa acagcaactt taatcttagg agctattgtg gggatagcta
     7501 gttccttgtt actattttat tctgtcaatc ttctatattt cgagcaattc cgccgagata
     7561 tcttgattaa acgaatttca ggtttacgat tttttgaaac acatgctcag tatatggtta
     7621 gccaatttgc cagttttgta tttggtgcta gtctctttat tttaagcagt cgagacttgg
     7681 tgattggctt gctcacttta ttggtctttc tagctagtgc agttttgacg ctttaccgtc
     7741 aagcgcagaa agaatctcgt gtttctatga caattatgaa aggaaaatag gatgattgaa
     7801 ctaaagaata tatctaaaaa atttggaagc cgtcagctat tttcagatac gaatcttcat
     7861 tttgaaggtg ggaaaattta tgccttaatc ggtacaagtg gctgtggtaa gacaacactc
     7921 ttgaatatga ttggacgatt ggagccatat gacaaagggc aaatcatcta tgatggcact
     7981 tctcttaagg acatcaagcc ttctgttttc tttagagatt acttaggata cttatttcaa
     8041 gattttggct taattgaaag ccaaaccgtc aaagagaatc tcaatctgag tttagttggt
     8101 aaaaagttga aggaaaaaga gaaaatctct ttgatgaaac aagctctaaa ctgtgtaaac
     8161 ctctcttatt tggatttgaa gcaacctata tttgagttat caggaggaga agcacaacgt
     8221 gttgcactag cgaagataat tttaaaggat ccgcctttga ttcttgcaga tgaaccaacc
     8281 gcttccttag accccaaaaa ttctgaggaa ttactttcca tcctagaatc tttaaaaaat
     8341 ccgaatcgga ccattattat tgcgacccac aatcctctga tttgggagca agtggatcag
     8401 gtcattcgag ttaccgattt atcacataga tgatatggta agattcagtt agaagaaaga
     8461 gtcacaaaca cactttgtgg cttttttatt tccataaaaa tggtaaaata gtaggagtag
     8521 aaatggagtt cgagacatga aagtaataga tcaatttaaa aataagaaag ttcttgtttt
     8581 aggtttggcc aagtctggtg aatctgcggc tcgtttgttg gacaagttag gtgccattgt
     8641 gacagtaaat gatgggaaac cattcgagga caatccagct gcccaatgtt tgctggaaga
     8701 agggatcaag gtcattacag gtggccatcc tttggaactc ttggatgaag agtttgccct
     8761 tatggtgaaa aatccaggta tcccctacaa caatcccatg attgaaaagg ctttggccaa
     8821 gggaattcca gtcttgactg aggtggaatt ggcttatttg atttcagaag caccgattat
     8881 tggtatcaca ggatcgaacg gtaagacaac cacaacgact atgattgggg aagttttgac
     8941 tgctgccggg caacatggtc ttttatcagg gaatatcggc tatccagcta gtcaagtggc
     9001 ccaaactgcg tcggacaagg acacgcttgt tatggaactt tcttctttcc aactcatggg
     9061 tgttcaagaa tttcatccag agattgcggt tattaccaac ctcatgccaa ctcatatcga
     9121 ctaccatggg tcattttcgg aatatgtagc agccaagtgg aatatccaga acaagatgac
     9181 agcagctgat ttccttgtct tgaactttaa tcaagacttg gcaaaagact tgacttccaa
     9241 gacagaagcc actgttgtag cattttcaac acttgaaaag gttgatggag cttatctgga
     9301 agatggtcaa ctctacttcc gtggtgaagt agtcatggca gcgaatgaaa tcggtgttcc
     9361 aggtagccac aatgtggaaa atgcccttgc gactattgct gtagccaagc ttcgtgatgt
     9421 ggacaatcaa accatcaagg aaactctttc agccttcggt ggtgtcaaac accgtctcca
     9481 gtttgtggat gacatcaagg gtgttaaatt ctataacgac agtaaatcaa ctaatatctt
     9541 ggctactcaa aaagccttgt caggatttga caacagcaag gtcgtcttga ttgcaggtgg
     9601 tttggaccgt ggcaatgagt ttgacgaatt ggtgccagac attactggac tcaagaagat
     9661 ggtcatcctg ggtcaatctg cagaacgtgt caaacgggca gcagacaagg ctggtgtcgc
     9721 ttatgtggag gcgacagata ttgcagatgc gacccgcaag gcctatgagc ttgcgactca
     9781 aggagatgtg gttcttctta gtcctgccaa tgccagctgg gatatgtatg ctaactttga
     9841 agtacgtggc gacctcttta tcgacacagt agcggagtta aaagaataaa atatgaaaaa
     9901 aattgtcttt acaggtgggg ggacggttgg acacgttacc ctcaatcttt tgttaatgcc
     9961 caagttcatc gaagatggtt gggaagtcca ctatatcggg aacaagcgtg gtatcgaaca
    10021 ccaagaaatc cttaagtcag gtttggatgt cactttccac tccattgcga ctgggaaatt
    10081 gcgtcgctat ttctcttggc aaaatatgct ggacgtcttc aaagttggct ggggaatcgt
    10141 ccaatcgctc tttatcatgt tgcgacttcg tccacagacc cttttttcaa agggaggctt
    10201 tgtctcagta ccgcctgtta tcgctgcgcg tgtgtcagga gtgcctgtct ttattcacga
    10261 atctgacctg tctatgggct tggccaataa aatcgcctat aaatttgcga ctaagatgta
    10321 ttcaaccttt gaacaagctt cgagtttggc taaggtcgag catgtgggag cggtgaccaa
    10381 ggtttcggac aaaaacactc cagaaccaga tgaattggtg gatattcaaa cccactttaa
    10441 tcccaaattg ccaactgtat tgtttgtcgg cggttctgca ggcgctcgtg tctttaacca
    10501 attggtgaca gaccataaga aagaactaac agagcgctac aatattatca atctaactgg
    10561 agattctagt ctgaatgagt tgaggcaaaa tctttttcgt gttgactatg tgaccgatct
    10621 ctatcaaccc ttgatggaat tggctgatat tgttgtgaca cgaggtggtg ccaatacgat
    10681 ttttgagctc ttggcgatag caaaattgca tgtcattgtt ccgcttggtc gtgaagctag
    10741 tcgtggtgac cagattgaaa atgcagctta ctttgtaaaa aaaggctatg cagaagacct
    10801 tcaagaaagc gatttgacct tggatagttt ggaagagaag ctttctcact tactaagtca
    10861 caaggaagat taccaagcta agatgaaagc ttctaaggaa ttgaaatctc tagcagattt
    10921 ttatcaattg ttgaaaaaag atttatcata aggaaagtaa atgtcaaaag ataagaaaaa
    10981 tgaggacaaa gaaaccctcg aagaattgaa agagttatca gaatggcaga aacgaaacca
    11041 agaatatcta aaaaagaagg ctgaagaaga ggcggctcta gctgaggaga aggaaaagga
    11101 aagacaagct cgaatgggag aagaatctga gaagtcagag gataaacagg accaggagag
    11161 tgaaacagac caggaagatt cagaatcagc taaggaagag tctgaagaaa aagtagcatc
    11221 ctcagaggct gacaaagaga aagaagagaa agaagaacca gagtctaaag agaaggagga
    11281 acaggataaa aagctttcta aaaaggctac aaaggaaaaa ccagccaaag caaagattcc
    11341 tggtatccat atcttgcgag ccttcacgat tttatttcca agtctgcttt tattgattgt
    11401 ctctgcctac ttgctcagtc cttatgcgac catgaaagat attcgtgttg agggaacagt
    11461 gcaaactaca gctgatgata ttcgacaggc ttcaggcatt caggattcgg attatacgat
    11521 taatcttctg ctagacaagg caaaatatga aaagcagatt aagtctaact attgggttga
    11581 atcagctcaa cttgtctatc aatttccaac taagttcact attaaggtca aggaatatga
    11641 tattgtggcc tactatattt ctggtgaaaa tcattatcct attctttcca gtggtcagct
    11701 tgagactagt tctgtgagtc tgaacagttt accagaaact tatttatcag ttctctttaa
    11761 tgatagtgaa caaatcaagg tttttgtctc agaacttgct caaattagcc cagaactcaa
    11821 ggcggctatc caaaaggtgg aattagcccc aagcaaggtg acatccgatt taattcgatt
    11881 gaccatgaat gattcggacg aagtcttggt tcctctatct gaaatgagta agaaactgcc
    11941 atattacagt aagattaagc cacaattgtc agaaccgagt gtggtcgaca tggaagctgg
    12001 aatttacagt tacactgtgg cggataaatt aattatggag gctgaggaaa aagccaaaca
    12061 agaggccaag gaagccgaga aaaaacagga agaagaacag aaaaaacaag aggaagagag
    12121 caattgaaat caaacgaccc agcgctcatc gcgtcgctag gtttaccttt tctcttatag
    12181 ttctttagtg accatgtttt tacttgacaa gtgctagtag aaataataga ataatagaaa
    12241 acctttaaag cagtccagag aggcagctaa ggttagacgg tgaaagggtg gagactaccc
    12301 atttttcgtg gaaccttgct gttggcaggt tccttttttc gtggcttctg ttggccagac
    12361 tctctcacta gtaaaggtaa aaggagaaac ctatgcgaga acatcgtcca atcattgctc
    12421 ttgattttcc tagttttgag gcggtcaagg aatttttagc tcttttccca gcagaagaaa
    12481 gcctttatct caaggtaggg atggagcttt attacgcagc ggggcctgag attgtgtcct
    12541 acttaaaagg tttgggtcat agtgtctttt tggatctcaa acttcatgac attcctaata
    12601 cagtcaagtc agcaatgaag atcctatctc agcttggtgt cgatatgacc aatgttcatg
    12661 cggctggtgg tgtagagatg atgaaggctg cgcgtgaagg tcttggaagt caagctaaat
    12721 tgatcgctgt aactcagctc acatcaacgt cagaagctca gatgcaggag tttcaaaata
    12781 tccaaaccag tctgcaagag tctgtgattc actatgccaa gaagacagct gaagctggct
    12841 tggatggtgt tgtttgctcg gctcaggaag tacaagtcat caagcaggct accaatccag
    12901 attttatctg tctgacacca gggattcgtc cagctggtgt tgcagttgga gatcaaaaac
    12961 gagtcatgac acctgctgat gcctatcaaa tcggcagtga ctatatcgta gtgggacgtc
    13021 ccattatcca agctgaggat cctgttgcag cttatcatac catcaaggat gaatggacac
    13081 aggactggaa ttaaagaact agattagaaa aataaaagga gaataccatg acacttgcta
    13141 aagatatcgc tagccacctc ttgaaaatcc aagccgttta cctcaaacca gaggaaccct
    13201 tcacttgggc atctggtatc aagtcaccga tttacactga taatcgtgtg acactagcct
    13261 atccagaaac tcgtacccta attgaaaatg gttttgtgga tgctatcaaa gaagcctttc
    13321 ctgaagtaga agtgattgca ggaactgcaa cagcagggat tccacacgga gccattattg
    13381 ctgataagat gaacttgcct tttgcctaca tccgtagcaa accaaaagac cacggagctg
    13441 gtaatcaaat cgaaggtcgc gtagctcaag gtcaaaaaat ggtagtggtt gaagacctta
    13501 tttcaacggg tggttcagtt cttgaagctg tagcagcagc caagcgagaa ggagcagatg
    13561 tacttggagt tgtagcgatt ttcagctacc aattgccaaa agcagataag aactttgcag
    13621 atgctggtgt taaacttgtg acgctttcaa actatagcga gcttatccat ctagcccaag
    13681 aagaaggtta catcacgcca gagggccttg atcttctaaa acgctttaaa gaagaccaag
    13741 aaaattggca agaaggttag gtcagtaaga taaagagaga cgaggctacc gagcctcttt
    13801 taccatttta ttt
//
LOCUS       DBEROT010000049        13366 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.49, whole genome shotgun sequence.
ACCESSION   DBEROT010000049 DBEROT010000000
VERSION     DBEROT010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.49"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            70..1329
                     /locus_tag="ACL8CG_001851"
     CDS             70..1329
                     /locus_tag="ACL8CG_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGS1344399.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1405..1540
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1579..2079
                     /gene="rplJ"
                     /locus_tag="ACL8CG_001852"
     CDS             1579..2079
                     /gene="rplJ"
                     /locus_tag="ACL8CG_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGS1344400.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2155..2523
                     /gene="rplL"
                     /locus_tag="ACL8CG_001853"
     CDS             2155..2523
                     /gene="rplL"
                     /locus_tag="ACL8CG_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGS1344401.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2710..2883
                     /locus_tag="ACL8CG_001854"
     CDS             2710..2883
                     /locus_tag="ACL8CG_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344402.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQS"
     gene            2880..3128
                     /locus_tag="ACL8CG_001855"
                     /pseudo
     CDS             2880..3128
                     /locus_tag="ACL8CG_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3142..3465
                     /locus_tag="ACL8CG_001856"
     CDS             3142..3465
                     /locus_tag="ACL8CG_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344403.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNLW
                     EVSHD"
     gene            3458..3838
                     /locus_tag="ACL8CG_001857"
     CDS             3458..3838
                     /locus_tag="ACL8CG_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS1344404.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3851..4045
                     /locus_tag="ACL8CG_001858"
     CDS             3851..4045
                     /locus_tag="ACL8CG_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGS1344405.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIV"
     gene            4087..4674
                     /locus_tag="ACL8CG_001859"
     CDS             4087..4674
                     /locus_tag="ACL8CG_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1344406.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYCASLIS
                     FLWMYAQRKQAHKVNMKSRIKWIGIGLASLLIISLCFSLIHAQESTNQANLIGLQYQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4876..5013
                     /locus_tag="ACL8CG_001860"
     CDS             4876..5013
                     /locus_tag="ACL8CG_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGS1344407.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5192..7801
                     /locus_tag="ACL8CG_001861"
     CDS             5192..7801
                     /locus_tag="ACL8CG_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGS1344408.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSERLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGGIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7834..9774
                     /locus_tag="ACL8CG_001862"
     CDS             7834..9774
                     /locus_tag="ACL8CG_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HGS1344409.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9771..11378
                     /locus_tag="ACL8CG_001863"
     CDS             9771..11378
                     /locus_tag="ACL8CG_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1344410.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11393..12133
                     /locus_tag="ACL8CG_001864"
     CDS             11393..12133
                     /locus_tag="ACL8CG_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344411.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12136..>13366
                     /locus_tag="ACL8CG_001865"
     CDS             12136..>13366
                     /locus_tag="ACL8CG_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS1344412.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYCKSY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILP"
BASE COUNT         4482 a         1881 c         2638 g         4365 t
ORIGIN      
        1 acctacggca aagtgaatct gaagtggttt gaagagagta caacttgtct tttaaaaaag
       61 gagtctataa tgaaagtctt tcagcatgta aatatcgtga cttgtgatca aaatttccat
      121 gtttatcttg atggaatctt agcagtcaag gattctcaaa tcgtctatgt cggtcaagat
      181 aagccagcgt ttttagaaca agctgagcag attatagact atcagggagc ttggattatg
      241 cctggtttgg tcaattgtca cacccattct gcaatgacag gtctgagagg gatccgagat
      301 gacagcaatc tccatgaatg gctcaatgac tatatctggc cagcagaatc tgagtttact
      361 cccgacatga ctaccaatgc ggtcaaagaa gccctgacag agatgctcca gtcaggaaca
      421 acaaccttta acgatatgta taatcccaat ggtgtggata tccagcaaat ttatcaggtg
      481 gtgaaaactt ccaagatgcg ttgttatttt tctccgactc tcttttcttc agagacagaa
      541 acaactgctg agactataag cagaactcga tccatcatag acgaaatctt aaaatataaa
      601 aatccaaatt tcaaggttat ggtagcacct cattctccgt atagctgcag tagagacttg
      661 ctggaagcga gtttggaaat ggcaaaagag ctaaatattc cgctccatgt ccatgtggcg
      721 gagaccaagg aggagtcagg aattatcctc aaacgatacg gcaaacgccc ccttgctttt
      781 cttgaagaac tgggttattt agatcatccg tccgtatttg ctcacggggt cgaattaaac
      841 gagagagaaa ttgaacgctt ggcatcttct caagtggcta tcgcccacaa tcctatcagt
      901 aacctcaaac tggcatcagg aattgctcca attatccagc tccaaaaagc gggagtagca
      961 gtcggaattg cgactgactc ggttgcttcc aataacaatc tagatatgtt tgaggaagga
     1021 aggactgcag ctcttcttca gaagatgaaa agtggggatg ccagccagtt tccaatcgaa
     1081 acagctctca aggtactgac aatcgaaggg gctaaggtcc ttggaatgga aaatcagata
     1141 ggaagtctgg aagtcggcaa gcaagcagat tttctggtca ttcaaccaca agggaaaatt
     1201 catctccaac ctcaggaaaa tatgctgtct cacctggttt atgcagttaa atctagtgat
     1261 gtagatgatg tttatatcgc cggagaacag gttgttaagc aaggtcaagt cctgacagta
     1321 gaactttaaa agaaaaatca cgaaaaattt taaaaaaagt ttgcaaaaat cttgcattct
     1381 ttttttgact atgctatact tatatacggt ttaaaaaaac tgcctaagac agtaggggag
     1441 ctcgactcat aaatatccta ccgaggacaa gacgtatcat gtaaaaagaa gcgtattgta
     1501 ctttcgtgtc taggtttggg cgcgtttttc tttttgaaaa attccccaag caaaataatt
     1561 acggaggtga acacactaat gagtgaagca attattgcta aaaaagcgga actagttgac
     1621 gtagtagctg aaaaaatgaa agctgctgca tctatcgtcg ttgtagacgc tcgtggtttg
     1681 acagttgagc aagatacagt tcttcgtcgt gagcttcgtg gaagcgaagt tgagtataaa
     1741 gttattaaaa actcaatctt gcgtcgtgca gctgaaaaag ctggtcttga agatcttgca
     1801 tctgtatttg ttggaccatc tgcagtagca ttttctaatg aagatgttat cgcaccagcg
     1861 aaaatcttga acgacttttc taaaaacgct gaagcacttg aaattaaagg tggtgcaatc
     1921 gaaggcgctg tcgcatctaa agaagagatt cttgcacttg caactcttcc aaaccgcgaa
     1981 ggacttcttt ctatgctcct ttctgtactt caagcgccag tgcgcaacgt tgctcttgca
     2041 gtcaaagcgg ttgcagaaag caaagaagac gcggcttaat cttaagctac acagcgtagc
     2101 ctagctacga aaaaaactat tataaaattt aaaacttatt tggaggaaat aacaatggca
     2161 ttgaacattg aaaacattat tgctgaaatt aaagaagctt caatccttga attgaacgac
     2221 cttgtaaaag ctatcgaaga agaatttggt gtaactgcag ctgctcctgt agctgttgct
     2281 gcagctgatg cagctgatgc tggtgctgct aaagattcat tcgacgttga attgacatct
     2341 gcaggcgaca aaaaagttgg cgttatcaaa gttgtacgtg aaatcactgg tcttggtctt
     2401 aaagaagcta aagaacttgt tgacggtgca ccagcacttg ttaaagaagg cgttgcaact
     2461 gcagaagctg aagaaatcaa agctaaattg gaagaagctg gagcttcagt tactcttaaa
     2521 taatagagta tcgcaatttg attgcggaat ccctatttac cagtctttga gagcgataag
     2581 cgattgatag aaactgataa attgatttgc tttcctgcca aaaattcttt ggcaggattt
     2641 ttgttttaat aaactttcgg gggtagacac tagattgtct accccttttt ttgtgtttcg
     2701 gaggtaatta tgcaaaagga aggacagtca tcacgtcaat tcgtgaagag tcatctcatg
     2761 actatcatgg gagttgatat tgtaaaagca actcagttag ttgatgaaat ggaacaagta
     2821 ggtttaatcc gatttgatga atttggaaat gttggaattt tagtcttgga gggacaatca
     2881 tgaagcgtat taccgctagt caatatcaga catcagagcg ttattataag ctccccaaac
     2941 ttttatttga gagtgaacgg tataagaata tgaaactgga ggttaaggtg gtttactcag
     3001 ttttaaaaga tcggttggag ttgtctttga gcaaaggttg gattgatgag gatggggcta
     3061 tttatttgat ttattccaat tcaaatttga tggcactttt aggctgttca aagtcaaaat
     3121 tactctccat gtgagtttga agtgacattt ttagatgatt accataaaaa acataactac
     3181 ccactatttt acgaatccta tcttcaaaac attatggaat tccttgaaag tcaggatata
     3241 aagaacggag ctgatgcctt tgtagatgat catcaaaatc ttgtttttgt tttatatgga
     3301 caaggctatc gagccgaggg aaaagaggga atacttacaa cccaagtaac tgtaaaagct
     3361 tatgatgaag acaagcaacc gattaacttc gcaaatttat tagattcctt aatcgtctca
     3421 gagtatcaaa tggaaccgaa tctttgggag gtctcccatg attgatctct atctaagtaa
     3481 aaatagccaa agaaatcaac ttcttttaga cttcttccaa aactatggca tcgaggtatc
     3541 ttgtcattca gtttctgaaa tgacaaagga taaattaatt gagatgatga gctattcttc
     3601 agattgtttt gagtttttat ctcccaattt attacgattt aagaaccgtg acaatttaag
     3661 attaacggat ttcattgaaa tgatattaaa aaatcctgaa ctaaccatca gacttcctct
     3721 tgcagtttca aataagagag tttatccaaa tctaaatttg gaggaagcta gagctttatt
     3781 gccaagagat acgaaacaat tgatttacat ggcgcaaaca cattatttat ctaactaaag
     3841 gagaagcaat atggctgaac gattttggga gaacttgtcc attattttgg ctgaaagaaa
     3901 tatcagctgg attgagctaa ccagaaaaat gtttgcggga gagtttcact atccaagtga
     3961 attgaatcgt ttgtatcaaa agattcgtca ctacaagatg gaacaacgaa tgcctcaaag
     4021 tccatgggta gaaaggattg tgtaggtatt agatttagat tatgaagatt tatttcggag
     4081 gtaactatga aaagaataat tccagtttat atattccaac aagtaaatgt cctattggta
     4141 tctctatact tactgaaatt tctttgtatc ggtgagttaa ctatactaca gattctatat
     4201 tgtgcgtcac tcatttcttt tttatggatg tatgcccaac gtaaacaagc gcataaggtc
     4261 aatatgaaat caaggataaa atggattggt attggattag ccagtctact gattataagt
     4321 ctatgtttta gtctaatcca tgcgcaagaa agcacgaatc aagcaaactt aattgggctt
     4381 caatatcaag ttccttggtt ttcattttta ttgttcttaa tcaatgcgag tatggttgaa
     4441 gaatttctgt atagagaaat tttatggaac ttggttagaa aattagatat tcgagttgct
     4501 ttgacaagtg ttttatttgc cttagcacat catccaggaa ccattatagc ttggtgtttg
     4561 tatgtatcgc tggggatgtt tttagggctt gtacgctaca aattggactt atggggcagt
     4621 atggggttac atttggtgtg gaacctacta gtttatagtt tgctgctttt ttaaaatagg
     4681 taacctgatt tttaggtaac ttctaaaact aacttccagt tttgggagag agatggaagt
     4741 tactttgaaa agttacggaa acattatttt ctatgtgaca acattgtata attgcttgca
     4801 ttttactggt ggagagagta taatgagggt ggataaagta cttaatccca aaaatttaaa
     4861 taggaggagc tagctatggc agaagaagta ttaaatcttc aattagtatc tgttcaagtt
     4921 gacgaaacag atgaagttga tggaatgcga tttagtacat tcagtacaaa tcgttgcggt
     4981 aactggagtg cttttagttg ggaaaattgt taattcattt aaattgtaaa ctttagagat
     5041 tctctggagt tatggatgtc gttccaatat gtgcacgttg gaatgttagt gcttatatgg
     5101 ggagaatcca aaggattctc cctttttatt taaataagtc tgtctagcta tagatatatt
     5161 aagtttgata aaatttcttg gagattttgt tatggattat aatttcaatt tggagcatcc
     5221 tttctttttc actaataatg attatagtac agatactagc ataaagtacc aagtaagtct
     5281 gccttttaat tggcacgaag taatgaataa tgatgagtgg gtttatcaat accctattgg
     5341 aaaatttgtt gaaagacaag ggtggaaaat acacattagt tcagagtata acagttcaca
     5401 tgaattgtta caagatgtag caaaaatttg ccatgaaatg cgaattccat ttaaacatct
     5461 tagtacagaa gacaaattta tcatgcgaaa cgggaaattg gttagtcgag gattttctgg
     5521 taaatttatt acatgttatc caaatcaaaa tgaattagag tcggttttgc aaaggttaga
     5581 aagtgcttta aagcaatata atgggccata tattttaagc gataaacgtt gggatgaagc
     5641 accaatatat ctgaggtatg gtgtgtttag gccgtcaagg gatgatgaaa agaaggttgc
     5701 tattgatgaa ttaattgttg gcgatgaagt tgttaaagat gaacgtttac cagtatttaa
     5761 aattccaaaa ggtatagtgc cccctgactt tttgaataaa tggcttgaca agaaagataa
     5821 aaaacaggga gactttccct ttattataga taatgcaatt agattttcaa acagtggtgg
     5881 gatatataat gctaggctaa aagaagatgg gaaaaaaata attttaaaag aggctagacc
     5941 gtatacaggt ctaggatttg atggtactta ttcttcagag agattagctt cggagtgcaa
     6001 agcactaaaa attctaaatg aatggagtga gacgcctaaa atatactggc acggtaagat
     6061 ctgggagcac accttcttag gaattgaaca tatgaagggc gttccactaa atagatgggt
     6121 taccaataat tttcctttat atgaagttgt tgataagacc aaagattatc tattgagagt
     6181 ttcaaagata gtagaaaaac tcatcgattt aacgaataag tttcattctg aaaatgtata
     6241 tcatcaagat ttacatttag gaaatatctt ggttaaggat gaagatgaga ttagtataat
     6301 agactgggaa caggctgtct tttcaaatga tgaaaaagtt gtacataaag ttgcagcccc
     6361 tggttttaga gcatggcgag aaacacttcc cagtgagata gattggtatg gtattagaca
     6421 aatagctcat tatttataca tgccactagt aactacatcg gatttgacat acaactatgt
     6481 aagtcaaacc aggatagaag gaaaaaaact atttgagtct ttgggttata caagagaaca
     6541 tatagattat gtagaaagtt tattgtcata tctagattct aaatgtccac agattgagaa
     6601 tatttccagg aaaaaagttt taaaacccat gcatgagatt agaactatcg agagtgagca
     6661 agatatacaa gattttatta taaaattatt gagagggttt acgctaactt atggacagtg
     6721 gcgtaaagaa tttcaatcaa gattcttccc agttcattat tatggtctga attttaatca
     6781 aggaattgcg ttttcagatt tagctatcct ttggagttat caacaactag ctaagaaagt
     6841 aaaaaatttc aagtttgatg actattatga gattcgaaca caggttatta atgaggcagt
     6901 aaataatttt aagaaatcgt ccctttctgg tctttttgat ggtaaaattg gtacaatctg
     6961 gctcatttat gaatttgggg agatagatcg ggcagttgaa ctttttacaa ctcattttat
     7021 agagatattt gagaattcac aaaataaaaa tttatatagt gggcaggctg gaattttact
     7081 ggttggactg tattttctta gtaaaggggg aattgataat aaactaggag aagaaatact
     7141 aattaggctt agagaatata ctttaaatta tatagaaaat ccagaaactt tttgtaaagt
     7201 tggcgctagt gatgttcaga gtaacgatcc ttatgagaat tttggtggat tactatatgg
     7261 tcacgcaggg gtagcttggc tcttcggtga agcttataaa ttaactggtg aaagtatcta
     7321 taaaaatggt ctagaattgg ctgtagataa agaattagtt gcttataaag tagatagtaa
     7381 taattcattg cagtacagcc aaggtcatag attactacca tatctagcaa ctggaagtgc
     7441 tggcctgctt ttacttatta atagaaataa agaaatcttg tcaagcaaat acttaaaata
     7501 tttaacttct ttagagaggg caactgatgt agttttttgt gtattaccag gtttatttaa
     7561 cggattttgt ggtcttgaag ttgctaataa tatatatagt gatatcgatg ataacttttc
     7621 aggacaaaag aaattaattg aacaacttta tagatatttg tgtgtaattg aagaaggatt
     7681 tgttattgcg ggagataatg gtttaaagat aacaacagat attgcttcgg gatttgcggg
     7741 tgttgcaatt ggattggtat caataatgga taataaattg acgattcttc ctcaaatata
     7801 atatttagat accattatta aggggtcata cttgtgaatc agagtaatga aatattttta
     7861 aatacaatac aggaaaaaac acactataag aggtctatct cttcatcatt tcaggaatta
     7921 aaaaaatgga attctttgat atttaggaga gggcgatatt ggtaccaatt tgataattgg
     7981 agtataccca atactggtgt aataaaggaa tggtatgtcg aagataatga ctggattcct
     8041 aaggttagtt cttccagttt agacaattca aattcactta aaattgtctt tgatgtggaa
     8101 aaatatactt tgccagatga tagtatctta caggatgtta ggatttcatc tgatgagagt
     8161 tatatagttt tggttgtatc ctcactgcgt agcactaatt taattggaat aaaaaaatat
     8221 actatggaag agttatttat cattgaagat atttcagtag aaagttcgtt ctatttgggt
     8281 aaattcggtg ttatgtatac tcgctccaaa gagtacggga ggccaagtaa gttattctat
     8341 aaatcttttg atagctttac agaagaggaa ctgtttgaag aaaacgaatg ctcttttcga
     8401 ttaaaaatag tccacattga tagcaataat tgttttgtaa agtcagtaga ctttcagaaa
     8461 ggcaggattt ttctatacag tttcgaccgg acgggttttg ttagacactc ttacacagaa
     8521 acggtagccc caacacctag agatatcgct ctatttagta cagaaaaagc acagtacttt
     8581 cttgggctct cttcaactga agaaaagaaa gatcaactaa ttctaaggga aacttcttcg
     8641 ggagacagag tttctattac tataccatat caagataggg ctagaagagt tcactgtata
     8701 ggacgttata tccttttaga ctgttcaaac gcagcgaatt ccgtctttta tcttgctaca
     8761 tttaaaaata atagtttgag ggagttgagt gttaataaga taacatttga tgaaaagaca
     8821 acactttatg aaaattcatt ttctgatcgt gttcttctgt ttttagagag gagaactttt
     8881 tacgaaaaaa tacttagttt tgatttaata gaaaatacat taaaaactga atttgaaaga
     8941 cccatcataa aatcgaataa tactaaatat ttttctaagg tgatttggac taaaaaagac
     9001 agttatgatg taagcatacc gatttcttta ttttggaaaa gtgaagatac ggatgagctc
     9061 ccaagaagaa aaaaatgtat tctaagtgtc tatggggctt atggtaagaa tgataattct
     9121 gatttagatg aaattatgtt atctataata gatgcaggtt ttatttatgc tatagttcat
     9181 gtaagaggtg gaggctattt gggtggtgaa tggtatcgct caggaaaggc gttaaacaaa
     9241 tggaattcta tcagagattt tattgaggga gtaaattatt taagggaaaa tgatgtaatt
     9301 gacagtaagc gattaggttt aataacttct agtgcaggtg gaataattgc tggtgcggtg
     9361 ttgaacgagg aaaaaaattt attgcaaagc attctcttat tttcgccatt tataaatcct
     9421 tatgatacac ttcagaatcc aaatgatcct ctttctaaga ccgaaatagc agagtgggga
     9481 gatattagag accctgaagt aaaggcttat ataaagtcat attcgcctat gcaaaatatt
     9541 gaaaaggcac gagactcaaa tactgttata gttaatattt tgggtgagaa agacccatat
     9601 attaataata acgaagtgat agagtggtca aagaaattaa attctattgg agttaaaagt
     9661 ttgttgtatt taaacaaagc agctggtcat ggaggtttta ctccatcaga tgttctctta
     9721 atgattgata ctttaaatta tttctttgaa gaagtgggaa ggaataactt atgaattatt
     9781 taaaatttat aaaaaagact aaacttatat taatggggat tttaatattt ctatcttcgt
     9841 ttaatggtgt cttgctctca ggaattattg tatatgcagg tagtttaaat cagacttcct
     9901 cattttctga cgttctaaga tttggtgcta taagtattct gggttggtca gcaatctata
     9961 tatcaaatta ctatttagaa gtaacggaag catcaataac taaagatata aatgtaaaaa
    10021 ttaaacaagg atattttaga gaacagtatc tttcttctga aatggttaaa gattactcat
    10081 ctattatttc agttttgtca aatgatttga gattaatcga agaaaactat tttagacaaa
    10141 tttttgaaat aatttcttca atattgttgt tcatcgtctc tctaagtttt atgctttatt
    10201 taaacttcct agtttcaata atatttattg tattatcagc attgccgatt atagtacctg
    10261 tctttatgaa gaagatgttg tctaattcag ctaatgagta ctctaacagc aatgcagagt
    10321 atactcacat aataaaagaa atttttaatg gttttaagac attaaaatct tattctgtta
    10381 ctaaagaaat aattagtttg tcggataaaa agttggataa actagaagat tctactttta
    10441 atttgaaacg atcagaggtt ctttcaaaat tggttgcagt actaatttca ggtttttgct
    10501 ttctagttcc cttggttgta ggatgttatt ttgtaattta tcataaaagc ctttctttta
    10561 gtgaactgat aggtattttc ttagcaaacg ataaagtttt agggccgata caatcaattg
    10621 cctattcatt aaataagata aatacaacca aagatttaag gaaaccgttt ttaaaatact
    10681 taagtggaga gaagaatttt atagacgctg aacatgataa taacggactg tatacttcat
    10741 caatagatga gatacacatg aaagatgttg tatattctat tacaccagaa aataaattaa
    10801 gtattgactt ctcatttaag tcaccattta gggtattatt aacaggaact tctggtagtg
    10861 ggaaaacaac gattttaaat ttaattaatg gttctttaaa gccacaaaaa ggttatgtaa
    10921 atttgttatc acatgggaaa aagagttcag attcaatacc aacagttgat cagacaccat
    10981 atatttttga cactactatt cgtgagaacg taactttatt tcaaaatgaa tatttttcag
    11041 atgatcagat aattgaggtg ttaaaaaagg taaatctata tgaagaatta gaaaagatag
    11101 atatactaaa ttatcaatgt ggtgaaaatg gtagtaattt gtctggaggt caaaaacaaa
    11161 aaatagcttt agctagagct ctgattagaa ataataaagt gtacttattt gacgaaatat
    11221 cagctaattt agataatgat aattcaaatt ccatacatga tattctgttc aatttaggta
    11281 tttcatttat tgaagtttca catcattatg acttaaatga caagagatac actgatatat
    11341 ataaattgga aaatggaaca cttttcaaaa ttaagtgatt ggaggcaaga atatggataa
    11401 agattatata ttaaaagtga aagggctgta tcatcaattt ttactaggaa ataataaaac
    11461 gttgcaagtg ctgaaaaatg tttctctttc tgcttcgaga ggagaattta taagtattct
    11521 aggaattagt ggttctggaa agtcaacttt attaaaatgt atttctagtt tgcttgaacc
    11581 aacaagtggg gaagtaattt taaatggaat caacccctat aaaatcagaa atgcaaaatt
    11641 gtcaagtata agacgtaacg aagtatcttt tatatttcaa gcatacaatt taataccttc
    11701 cctgccggta atagaaaata tagcacttcc tttgcgatta tcacaaaaaa aattaactat
    11761 taaaaatgta gaaaacttac tcaaaagaat gaagtttaat gctggcttaa acgattttgt
    11821 tggaactctg tctggtggag aacaacagaa ggttgctata gctagagcgg ttattgctga
    11881 tagtgatata atatttgctg atgagccaac tggggcttta gacagcgttt ctcgtgaagt
    11941 aatttttgaa ttattgagag agttagtagg ggcgggtaag tgtgtaatta tggtaacgca
    12001 cgatatagaa ttggcctcga aaactgatcg tgcattaata ttgaaagatg gaaaaatttt
    12061 caaagaactt catagaccta gcggggaaga gttgtataaa atcttagagg tacaatcaac
    12121 tacggaggaa tagagatgct cagattagtt tactatcaat ttttacataa taagaaacaa
    12181 tggttaggcg tttcaccagt aatttttgtt tcgagtttag ttatgggatt ggctgttaat
    12241 ggggtaatta atgttgagaa taattcgcaa gtatttgtcg gacttccaga tcctaaacca
    12301 atttttatgt ttccgatagt attcggagga gtaacattat tctttgtgct ctctaacata
    12361 ataaatatgt tggttgaaat ttttagagat gattacgaac ttctggaggt gttgggagca
    12421 agtcgccttc aactatcatt tcttgtgggg ggacagattt ttatcatttc ctcgattatt
    12481 agttttattg catatctatg ctctatattt gttacgtcaa attattatta ttttttacaa
    12541 tactttttcg gggaaaatat attacctgat atccaatttc aaacgagtgc tgttggatgt
    12601 atcattacag tagtgttgat ttcattttta gcctttctaa gtggttgctt ttatacgttc
    12661 aagaagatta gaaataggaa gagttctaaa ataaggcatg ttctttcaat agtaaaaaga
    12721 atactgctat tggctggttt tagtgttatc tggttgcttt ctttgcaaca aattttccaa
    12781 gatagcacaa ttttagcgaa ggcccagata atattcaata ttgtaatctt agatattgtg
    12841 attatttatc aattatctcc ttttatacag tcatgtttta tcaaactact ttctataatt
    12901 atatttagaa ataattttat gttcattgtt tcgaagtgga atttactata ttgtaagtct
    12961 tatataaaat ctatcagtgc tgcaattaca ggagctatat tactaatttc tagttttcaa
    13021 atgatttctc agaatatact atctcaattt caagatgaca gtgatttaga gctaaaagta
    13081 gcatttattg tctatgtagg agcaccaatt ttgatagtac ttgcaaatat tatttcaatt
    13141 gcatttttgt catcgcatca agaaaggatt gagattcagc aatttgaaat tttaggaact
    13201 tctaattacc agatggttaa gattaaagtt ggtgaggcta tatttttgac atttgttact
    13261 tcattaattg catttttact taacattaaa attatggctt taatatacta ctctttagag
    13321 gatattttaa tagatgatat gaatcttttg gggttaatac ttccaa
//
LOCUS       DBEROT010000050        12645 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.50, whole genome shotgun sequence.
ACCESSION   DBEROT010000050 DBEROT010000000
VERSION     DBEROT010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.50"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(294..2021)
                     /gene="ezrA"
                     /locus_tag="ACL8CG_001866"
     CDS             complement(294..2021)
                     /gene="ezrA"
                     /locus_tag="ACL8CG_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGS1344413.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEEKKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2103..4049)
                     /gene="gyrB"
                     /locus_tag="ACL8CG_001867"
     CDS             complement(2103..4049)
                     /gene="gyrB"
                     /locus_tag="ACL8CG_001867"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGS1344414.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4064..4627)
                     /locus_tag="ACL8CG_001868"
     CDS             complement(4064..4627)
                     /locus_tag="ACL8CG_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1344415.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4712..5266)
                     /locus_tag="ACL8CG_001869"
     CDS             complement(4712..5266)
                     /locus_tag="ACL8CG_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGS1344416.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAV
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5277..6500)
                     /locus_tag="ACL8CG_001870"
     CDS             complement(5277..6500)
                     /locus_tag="ACL8CG_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS1344417.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFCMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6537..8987)
                     /locus_tag="ACL8CG_001871"
     CDS             complement(6537..8987)
                     /locus_tag="ACL8CG_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGS1344418.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVFLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9187..10116)
                     /locus_tag="ACL8CG_001872"
     CDS             complement(9187..10116)
                     /locus_tag="ACL8CG_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGS1344419.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKIDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQVFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10256..10543
                     /locus_tag="ACL8CG_001873"
     CDS             10256..10543
                     /locus_tag="ACL8CG_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGS1344420.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10577..11911)
                     /gene="ciaH"
                     /locus_tag="ACL8CG_001874"
     CDS             complement(10577..11911)
                     /gene="ciaH"
                     /locus_tag="ACL8CG_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGS1344421.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11901..12575)
                     /gene="ciaR"
                     /locus_tag="ACL8CG_001875"
     CDS             complement(11901..12575)
                     /gene="ciaR"
                     /locus_tag="ACL8CG_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGS1344422.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         3846 a         2707 c         2242 g         3850 t
ORIGIN      
        1 aagttactca aagtacagat ttgaagctgc agataagact gacgaaatca ctttaatact
       61 aaatgaaaat caaaaagcaa actaagaagc tagcctcagg ctgtacttga gtacggtaag
      121 gcgacgctga cgtgatttga agagattttc gaagagtata aaacactgtt ttgaggtggt
      181 ggataaatcg gctgggtaaa aactcaatct caggagaaaa tgaagtaaat ctccccacaa
      241 ctatagaaaa agatttgatt ctgctcctca cacaataaaa tctttttctt ttattaaaaa
      301 cgaatcgttt cacgtgtttt ctcatatgag gtaacaaagc gattagttac accaggctct
      361 gccacttcca atgcttgaga aatcttgtca aatgaagcgt gataatcaaa ttctttttca
      421 aaaatatcta aagcttcgtt aaatgcttct tgaatgcgtt catcaaatga gcgatagcgg
      481 ttagaatatt gcaagagttg ctctgtcaaa gttgcatatt gtacaatatt ataagtttcc
      541 gtttctaaag cttccatatc attcgttgca atttcaagaa ctcgggtaac agattcaatg
      601 ttaatcattt tttgttctaa ctcaaccatt aaatcctcgg tattattgct tgccgtaaag
      661 aataacttca agaaagtttg tggaatacct ggcagattgc gtttttccat gtatcgcttg
      721 atagtatgga gacgattgac ataaacattg gccttttgac gtgcattaat atcatctttc
      781 tcaatttgtg tcaggcgctc actaactgaa atttgctcat cttcaatatc ttttagttga
      841 gtttgtaaat cctcaagatt ttcttcaaga actgaataag cttggggtgg ttcttcttga
      901 tttgaagtta cctcaacaat agctgcctca aaactctcta attctgtctg aatacgacga
      961 acatggcttg cagctgtctc aggaagtaaa taggtcttgt tcaaacgtgc aatatcttct
     1021 cccaataaag tattattctc tttcatatgt tgaagataag ttggaagagt tgcaagtaga
     1081 ttttccacta ctttctgagc agcaatttct cgagtaaaaa tatcatacaa ggcattgatt
     1141 tcctcttgtg cctgtccatt ctcatattcg gcattatcca attccaactg acgaatattc
     1201 tcttggtttt tcttgaatgc ttcataaagc aagtggaaac gcgcttcaat atccgtttca
     1261 acaaaatgat aattagcatc aattagttta cgataaccgg cttccaaatc ctgtaattga
     1321 tctggcaatt ctgtagaaag cgtcgtaacc aaggctggaa cacgatccac aatatgactt
     1381 aaggccaaaa tgtgattttc tgtattatcc aaaatcactg cggcttccac agggtcaccc
     1441 gatgaattca aggttacaaa ttgtgaaaat tcagattgga tattttctaa ttgtttttca
     1501 atttcatcca aggcttgacc atactgttct gaattttcag caactctatg ctgaagttcc
     1561 tcaaataaat ccaaagcatg aagaacacga ccactatttt tagattcttg cttctctaag
     1621 tctgccaaag cattgcgaat tgccgcaata tcttcttcaa tcaaagtaat ttgactctca
     1681 atttggtcaa tttgatgact ggccttgaga aaacgaaatg aatggttata accttctgct
     1741 tcaaagagat tattttcaat atcggcaaaa gagttgagag ataaatcgac ccatttttga
     1801 ttccattcac ggaaagccac ttgactttgt ccaatcaagt gcatattttt tacagcttct
     1861 acttcatcat ttactggaag attgtatagt tcttcttttt tttcttctag cgcctctaat
     1921 ctcccctcgt ttcgcttacg tagaaagatt gccactacat aagccagaac taaaatgact
     1981 gcaattgcaa ccattaaata aattagttgt ccattagaca tatcaaactc cttttttact
     2041 tgaaacaatc gtaacgatta tatcatattt tttagaccaa gggaactact tctccctatt
     2101 ttttagacat caagtgtact atagacagca ttttcttcga taaactcacg acgaggctct
     2161 actcgatccc ccatcaacat atcaaagatt ttatctgctt ctgcagcatc atctacagaa
     2221 actctagcca tcaagcgatg ttcgggatcc atggttgttt cccacagctg atgatcgtcc
     2281 atttcaccta gccccttata acgctgaata gtcggtttgg tacgaccttc actataacgg
     2341 gctaaagctt cttggagttt gatttcttga tctgcacccg gctggatata ttctttaatc
     2401 tcgcttccaa ccttgacacc atagattggt ggttgggcaa tataaacata accagcttct
     2461 aggattggtt tcatataacg ataaatcaag gttaaaagaa gggtacgaat atgggctcca
     2521 tcgacatcgg catcggtcat caaaacgagt ttttggtaac gggctttcga aacatcaaat
     2581 tctgcgccaa atcctgttcc catggctgtg aaaagactac gaatttcttc gttagctaga
     2641 atcttatcca tacttgcttt ttcaacgttc aaaatcttac cgcgaattgg aaggatagcc
     2701 tgaaactcac ggttacgacc agatttggct gatccaccag ctgagtctcc ttcgacgatg
     2761 aagagttctg tttcagcagg gttattagaa gaacagtctg ctagtttccc tggaaggttg
     2821 gaaatttcca aaccagattt tttacgtgtg acttcacgcg cacgcttggc agccacacga
     2881 gccttggcag ctaaaatccc tttttccacg atacgtttgg caatctgtgg attttccatg
     2941 aggaaatcgg agaaggcttc actgaagagg cgattggtaa tcttgaccac ttcgctattt
     3001 cccaatttgg tcttggtttg tccttcaaac tgtggatttg ggtgtttaac tgagataact
     3061 gcagttaatc cttcgcgaac atcttcccct gttaaattat cttcattgtc tttcagtaac
     3121 ttattcttac gagcataatc attgataaca cgagtcagtg ccgtacggaa accttgttca
     3181 tgcgttccac cttcatgggt atgaatatta ttggcgaaac tcatgacatt ttcatggtaa
     3241 cctgttgtgt actgcatggc tacctcaact gtaatatcat ccatctcacc gtctgtatag
     3301 attggtgtat caaagattac atccttgttc tcgttgatat attcaacgta actagcaatc
     3361 ccaccttcat aatgataatg cttggtttgt tccaaacctt ggcgcttatc agtgatagaa
     3421 atttgaagac cgcgatttag aaaggccaac tcttgaatcc gtttatttaa tttatcaaaa
     3481 tcaaaggttg ttgtttcagt aaagattttt gggtccggta tgaagtgaac cgttgttcca
     3541 gttctatctg tatccccaac cacctcaagg tctgcaacaa catgaccacg acggtattct
     3601 tggtaatgaa tcttaccgtt tttatggaca tgaacgtcta attgagtgga aagggcatta
     3661 actactgacg accccacccc gtgaagacca cctgaaacct tgtatccacc accgccgaac
     3721 tttcctccag catgaaggac tgtaaagacg gtctcaacag caggacggcc tgttttttcc
     3781 tgaatatcga ctgggatacc acgcccatca tccacaacag taatcgaatc atctggctca
     3841 ataaaaactt gaatatggct ggcaaatcct gccaaggcct cgtcaattga gttatcaaca
     3901 atttcccaga ctagatggtg aagaccttct tttgaggttg atccaatgta catccctgga
     3961 cgcatacgaa cagcctctaa accctctaaa acttgaattt gactggcatc ataatcctgt
     4021 gcctgcagat ttttgatttc ttctgtcatc ttattccttt ttcttatatg tctaatactt
     4081 gtcttaaatt cacgatactg gtaaacaagt gggtatcaag tcctgcagct tgacctgctt
     4141 cgatatcaat cggccgatca ccaatgacaa gaccagagct aatctgatac ttttctctta
     4201 aataaagcat ggattcggga tttggctttc tcttaaagcc tgagctagaa gtcaccactt
     4261 ctgtaaaata agctgctata gaggtttttt ctaaaatttc caaaacctga tcatttcgat
     4321 gagagaccaa aaaatgacgg ccaccttgat ttaaaatgtc ttccaatagg tcagaaactc
     4381 cttcaaataa aatcgggtgt tcaagctctc tggcttcatt ttccttgtac ttttctaaaa
     4441 aattctctaa attgggagcg aatgtctcaa tcgcaaaagg agtagaaacc tttaaagctt
     4501 gatagacact gtcatggtct tgtgtgatac catacagtgc caatgtttca acaaatgcag
     4561 ctgttgaagt ttcataatta tccagtaaag ttccacctaa atcccagatg taatcgtgat
     4621 atttcatacc cttcattata gcattttttt atgaaaaaag cgatgatttc cctgagtttt
     4681 ccacataaaa aacgagagaa taactcccgt tttactgatt tttaccaaag acatctcgat
     4741 agagcattcc tgttcgtaaa ctctctgcgt cccctcctag ttgctccacc aactcgtagg
     4801 caaaggcaag ggctgttgaa ggaccccgac tggttgtcaa ctgaccatct accactactg
     4861 tttccttgac gtagtgacca tcaaggattt gctcttgaac gccgtcataa caagtgtatc
     4921 gcttattttt caatatctct gcttgattga gggcaattgg taccgcacaa atggctgcta
     4981 gtttcttccc ttcttgctcg aagctttgca attcttgaat caaggtctga ttatcacgta
     5041 aatgtgcaga accaggcata cctccaggaa gaacaatcat atcatagtct gataaatttc
     5101 catcaaagac atgatctgct cttacttgga ttgcatgcga acccgttact tgctcttcaa
     5161 aaccaaccat atcacatgtg atattggctc gacgcaagac atctacaact gtcaaggctt
     5221 caatttcttc aaagccctga gctaacataa ctgctacttt taccatgatt ttctccttat
     5281 ttaatttgtt ttaatacaac ctttttccgt ttgaatggga cttttccgct cttttcttca
     5341 gctagattag tctggtaact catcgataaa agcaaaccaa caccaatcag attactgata
     5401 atagctgatc ccccttgcga aatgaaaggc aagggaatcc ccgtcaaagg aagtagtcca
     5461 gtcacagcac cgatattctc aaagatgtgg aagagcaaca tcataatcaa acctgtggaa
     5521 atataagtgt agaactggtt atttgattta agagtaatct tcaacatacg gtaaatcaac
     5581 atgagataga gggcaataac caggacagag ccaataaagc caaaatcttc tgcaataacc
     5641 gtaaaaatca tatctgactc tcgaactggg ataagcagat tcgaagcatt aaatccctga
     5701 ccaaataagc caccactccc aatggcaatc tgcccttgag cctgctggta agtcgttgtt
     5761 tgggcaaact caaagggatt gagccaagcc aaaatccgat taatttggta ggtcggcatt
     5821 ccaatctggt gaagaaaagc tcgtccgtcc ttgctaataa agatagctaa gaaaccagca
     5881 actcctgtta cagcagtcac aaatactggg ataataattt tccaagaaac ccctgataat
     5941 aaaacgattc ctgagaaaat ggctacaaaa accaaagccg tccccaagtc actttgaagt
     6001 gctaaaagaa ctaggactgg aatggtaaag agaatcatac agaaaattaa caaaaagtcc
     6061 agcggaaccg tgcgtctcca ttccttatgt ttctttgtaa attggacaat gacacgagcc
     6121 aacatgagga tataggatat cttcataaat tctgacggtt ggaatagggt aattccattt
     6181 attgataccc agtttttggc acccgttgat gcaactaagc ttggattata aaatacaatc
     6241 ggcaagatca taagtcccaa gcctaaaata tatagaaagg gggtcacctt ccaaagaaat
     6301 tctgtattaa agagcatgac cacaaaacca atcacaagcc ccaaggcaat ccaggcgacc
     6361 tgctgcccta aaatgggcag aatattattg gggtaatcat gactaacggc tatatagata
     6421 gccaccacac cgatgaccag tagaaaaaat actggcaaga gcaaactgta atcgactctt
     6481 gagtcgagag aacgtttcat atatactaac cttatacttt catacaatac tatttatcaa
     6541 agttcattaa aaaatctatc aatagcctcg tcaacttcgg atcgagagat ggttttaaca
     6601 gtcgcttctt ctgctagaga tgctactatt tgtttgccgt atcgttttcc gacgattctc
     6661 ctatccaaaa taagagttaa ggaacgttgg tattcacgtc tcatacttct tcccaaagcc
     6721 tgttttaaac gaataatggc cattggcaat tgataatcat aaaaggcatt tttcccttct
     6781 tgattcagtt cttgattaat ctttttcgtc aagggttctt gaggattttg gaaaggaagc
     6841 ctcggtacaa cttgaatcac aaaaggatgg cttgaaaaat caactccctc ccagaaactt
     6901 gctgcaccaa gcaagatttg ttgttcacct ttttcaaagc gtttctttag ctgatgaaca
     6961 tccccatttt tatactgggc caagtggcta actgtaagta aatccgatac tgctagaagc
     7021 atgtctttag cggtaaagag aaccaaaatc ggttgctgga aagcttgaat ttccactagt
     7081 aaagcagcta cctctctggc atagacttct aaggaggttt ctgttaccag agggaaatct
     7141 ttgaccatga ccacttcttg ttcctgtttt ccccgagatt caatcttgac aaatttagct
     7201 tcaggatagc ctaaaaggtc tgccaaagaa accctctgac taatctcaag agtagccgat
     7261 actcccagga cttggcaact ctcaggaagt aaagaggaca gaagagtacg gcctgatttt
     7321 gtagaagaaa tctgaatttt cttttgactc gtttcagtta cttcaagcca gtaatcacct
     7381 tcagctgtaa aatagcgaac cagctcatca aagccttcta cttctaattc tgaaaaatac
     7441 tgatggagat tgtccagaga atctaagata tttttcctag atttaccaga ctgaaattgt
     7501 tctatcaagt agagacactc aaagcgaata ctttctagta tccgttgttg aaccctgttt
     7561 tcttctccta ctaaagcctt atcaattaaa tcgataatag attgtatatc gtaggtctct
     7621 tgaagcagat tttctagagc taacaaaatc ttttggactt catcaataat cagtaaacgg
     7681 tcactgacaa attcaggatt atcttcaagt ctggtcacga gataggcatg attagtcact
     7741 aaaagcttgc aagtctctgc cctttcttga ctacgtttcc aaaaatcttc cgtcacaaat
     7801 aagctctggg atgataaatt cccatcatga cgaaggtctg ctagaaaatg ttggtaacgg
     7861 tagagttgcc cgatttcatc caaatctcct gtctctgtct cagtaagcca gaccaagact
     7921 tgcattttaa agcgtctaaa taagcgattt tcatcatttt cctgcaagga atgataaaag
     7981 gcatccaact tcagataatt ttgtggtccc tttaagctat gaatatctgt atggaacact
     8041 tccttgagac gtttaccttc ttcttccatg atttgatttt gaagaatctt tgtcggaaca
     8101 ctaagaacaa tttgtcgctc tttggattga gataaagcgg gtaagagata gccataggtt
     8161 ttcccaatcc ctgtcggcgc ttgaatcaga aagacaggtt catctttcaa tagcaagcca
     8221 acctctttag caaaactttc ttgttcctcc ctcacttcaa ggttcaacag agaaatattt
     8281 ttagaaaagt cttgagatag ttttcgtagc tccagagaag ctgccgtttt cttaaaatac
     8341 agaccttgaa cttggaccaa gtctggagaa ctcaggatag attggttgcg ataagtttcc
     8401 tcaataacca ggtaggactc atataggaga gcgtcagcca tttccagcaa gcgttccaag
     8461 agacctttag gaagctgggt catcttttcc cgtaaaaaaa gaagtaattc tgctgtagct
     8521 tgggcatctg aaagggctgt gtgtgcgtgt ttaagaggaa ttcctaattc tcgacacaaa
     8581 atcggcaagc tatatttttc cagttcaggg aaaaagacct gggccaattc gaccgtatca
     8641 acacgagggt ttcttagctc atagccttca aaaaataaat tttccgccaa gagattagca
     8701 tcaaactgaa cattatgggc tacaaaaatc ccatcctcca ccaagtcaaa tatttttctg
     8761 gcaacttgcg aaaaatcagg tgcttgcgcc agacgttggt ctgtcaatcc tgtcagttct
     8821 ttgatatgag catccaaggg ttcatgtgga ttgacatccg tcgtatagtg atcgacgatt
     8881 tctccgtcct caatcacgac aattcccact tggataattt tagccttact acctgtgcta
     8941 gttgcctcta aatccaccac aacatagcga ttaccaatcg ttttcattat aaaaaattat
     9001 accaaaaaaa gggccatttg gcacctgcaa acataggata attttcaaac tcaagaacac
     9061 tacttttctt aaaaatccca tcgaatagag cattctagcc tgctgatttt tgtaaaatag
     9121 tgaagaaata cgaaaaattg agagaagaaa tgtttgcatc ttccttctct caacgaatca
     9181 tgtattttat ctaaccatgt caggatcgta gtcataaaat cctgtatcaa ggaaacggtt
     9241 tttagggtga agtttacgaa cttcttcatc cagcaagaag acttgatcat ggctaaagtt
     9301 gccctcttga atcaagttac gcgcttggat aaagagtttt gcaatctcaa caaagttctg
     9361 accaggagtg tagagccctt ctagtttcca gcgagtaaag ccatgctcca ccaattctgt
     9421 taatttgatc atcaaatcaa ggtcattgtt ggcaaagata tgggtcccat gattatcttc
     9481 aaaaatggaa tagtggctct ctggatcact tggctcagcc aagaagaggt cacgtttatg
     9541 cgtcttttca tcatcgatat gtgtaaagtt atagtagttt tgcaagagtg gacgtttaga
     9601 atgatggatg acgctagcac cgtaaaccaa aacttcagca ggaatttcca aaatctctgg
     9661 cattttgaaa agttcagctg atggaatttc acgcgccaaa acagcctcag atgcgccagc
     9721 cttttgtccc cagaagttaa tctgacgact gctagttacc atggttgaag catcgtagat
     9781 ggtcttaaat gaataaccat cgcggttaac tacgtaaaag acgcctgcat ccccaatcgt
     9841 aatatagtct atcttgattt cttccaagaa gtctaagaaa ggcttgatac ggtccatcat
     9901 atcttggtgc atgagagcat tgaccgcaac gagcaattcc ttaccagcat catgaaccaa
     9961 cttagcgatt tcacgtaatt ggtcataact aaaggtcgtt ggcagacgaa ggccaaaatc
    10021 tttctcaccg acatagatac ggtctacgcc agcttcgagt agttgttcaa cttgttcaat
    10081 actttcagca gttgctgtaa tgacaatctt ttccataaga aaaattatac cacatttctc
    10141 caaaatcatc catgctttga aaatgaaaag ggactttatt ctttttgtaa cctttctgta
    10201 ataattctct gccgaaaaaa tgataaaata ggtatgtact gttaaggaga gaattatgcc
    10261 cgtaagaaaa ttacaatcct atgaggtaga ctatcaagaa gaattaaacc agcagcttcc
    10321 tcattaccaa gcttatacac ctgaagcgca atctgatgcc aatctcaagg aaatcctatt
    10381 ttttattaat atcgctgttt tttgtatctg tattgctatc tttagtttta tctttttagc
    10441 attaaaatta tcaactgctc ttgcctttgc cgcagcaatc ggattcagct tacttgtttt
    10501 aaaagttcaa cggtctatta tcaaacgaaa acgtagaaga taaatccaaa atatcgcccc
    10561 aattggagcg atatttttat tttttctttt tagatggtgt ctgaatggca atcttcactt
    10621 caaagattgt tcccttgggt ttattatctt tgacagtaac agttcctttt agagcatcta
    10681 caatttgctt ggctagggat aatcctaaac caaaaccacc tttttgccgg gttctagcct
    10741 tgtctactcg ataaaaacgg tcaaaaattt tctttttatc ttctgtcgaa ataccgattc
    10801 cattatcaga aacaagtaaa taaagattgc gatcggtcgc cgagataaga aaatcaattt
    10861 caccatcctc ctcagtatac ttgacggcat tatcgaaaag aatggtcatc agttgtttca
    10921 gaagaagctg atctgtgaca attgttcgat ggatacgatt ttcaaaacgg aagacacgat
    10981 tattttccga agcaatcatc tcatagtttg tgaaagttgt attaaaaaag ctagttggaa
    11041 cttctgcaag ctccggctta atcccatcat ctctccgagc taagttcagc aagcttgtcg
    11101 ttaaaaaacg catatttcgg acttcttcca aactcgatgc aatgctttcg ctcacatcca
    11161 taatggtagc ttctggctta cgaaaaaggg tctctaagcg attttgcaaa actgcgagtg
    11221 gagttcgtaa ctcatgactg gcattttcca caaaagactg ttgcttctgc atactctcaa
    11281 gcaggggcct aacactgacc ctagctagat agagactggc aagtaaagac aaaatccaga
    11341 aactagccat cacgaccaca atcaattgct catgcttttg actagcctgc tccaactgac
    11401 tggtattaat caagacagca gcatacttga tattggttga aaccgaacta atattggtct
    11461 ccatcaaaat cacacgatag atttcttcct gcccatagct attaaaaacc tgaatctggt
    11521 agatatgtcc tagttctttc ttttctaact taatcttatc caagcccaaa aatcgatttc
    11581 cagaaagaag ttgagtaaag tctttatcaa agagaatgac ttccgtattg gaactgacat
    11641 taggttttat ttctacttta ctagcgtccg ccctagcatt ttctaaatct ttaatctctt
    11701 ctgttgccct atttatagcc agctgaataa ctgcttgagg attttcactc agtccatgaa
    11761 gcttatcgtc caccgaagta taaagactcg aatgcatgac ttgtaaaata atcagagtca
    11821 ttgtagaaaa aatcagggtg aagacaccga agttgcggat aaaataacta aagtcatccg
    11881 cataccatgt ttttttaagt ttactgaaca tcttttaaaa gatacccaac actacgcaaa
    11941 gtttgcaaat tctctgcaaa agtggttccc tttaatttct tacggacttt tgaaacatag
    12001 acttcgacaa ccgaaatcgt tgtatcacta tcaaatcccc atagacggtc aaaaatctgc
    12061 gtcttaggca aaatcacatt ttgattttga aggaaataaa ctagtaaatc gaactctttc
    12121 cccagcaatt cgacaggagt atcttcaact ttaacggtat tggttgataa attaaccacg
    12181 atattcccat aagtcaaggt gttttcatta aacttccctg aacgtttgag aagggcctga
    12241 atccgcattt taagttcttc taggtagaaa ggtttggtca gataatcatc cgctcccagt
    12301 tcaaatccat gtcccttgtc atccaaactt tccttggcag tcataatcag aactggtgtc
    12361 gtaattccct tttcacgcaa ttcttttaag acttggaaac catttttttc tggcaacatc
    12421 aaatccagca aaatcaagtc atagacacca ctctcagctt cgtagagacc ttcttctcca
    12481 tcaaatacct gcataacatc cgcaaaatcg tctaaaaagt caaatactga atttgacaga
    12541 cctaggtcat cctcaaccaa taagattttt atcatgagaa actcctcctt attaaaacta
    12601 ttataccaaa tttgccttaa aaaaaactca actctctgca tttta
//
LOCUS       DBEROT010000051        12027 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.51, whole genome shotgun sequence.
ACCESSION   DBEROT010000051 DBEROT010000000
VERSION     DBEROT010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.51"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(156..1358)
                     /gene="rpsA"
                     /locus_tag="ACL8CG_001876"
     CDS             complement(156..1358)
                     /gene="rpsA"
                     /locus_tag="ACL8CG_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGS1344423.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRTARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1520..1591)
                     /locus_tag="ACL8CG_001877"
     tRNA            complement(1520..1591)
                     /locus_tag="ACL8CG_001877"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1557..1559),aa:Gln,seq:ttg)
     gene            complement(1601..1681)
                     /locus_tag="ACL8CG_001878"
     tRNA            complement(1601..1681)
                     /locus_tag="ACL8CG_001878"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1645..1647),aa:Tyr,seq:gta)
     gene            complement(1731..1961)
                     /locus_tag="ACL8CG_001879"
     CDS             complement(1731..1961)
                     /locus_tag="ACL8CG_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGS1344424.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2129..2773)
                     /gene="pcp"
                     /locus_tag="ACL8CG_001880"
     CDS             complement(2129..2773)
                     /gene="pcp"
                     /locus_tag="ACL8CG_001880"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGS1344425.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2788..3711)
                     /locus_tag="ACL8CG_001881"
     CDS             complement(2788..3711)
                     /locus_tag="ACL8CG_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGS1344426.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3708..4397)
                     /locus_tag="ACL8CG_001882"
     CDS             complement(3708..4397)
                     /locus_tag="ACL8CG_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGS1344427.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4462..5166)
                     /locus_tag="ACL8CG_001883"
     CDS             complement(4462..5166)
                     /locus_tag="ACL8CG_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1344428.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5222..6244)
                     /locus_tag="ACL8CG_001884"
     CDS             complement(5222..6244)
                     /locus_tag="ACL8CG_001884"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGS1344429.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6376..8847)
                     /gene="parC"
                     /locus_tag="ACL8CG_001885"
     CDS             complement(6376..8847)
                     /gene="parC"
                     /locus_tag="ACL8CG_001885"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGS1344430.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9048..9252)
                     /locus_tag="ACL8CG_001886"
                     /pseudo
     CDS             complement(9048..9252)
                     /locus_tag="ACL8CG_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(9267..11210)
                     /gene="parE"
                     /locus_tag="ACL8CG_001887"
     CDS             complement(9267..11210)
                     /gene="parE"
                     /locus_tag="ACL8CG_001887"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGS1344431.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11346..11987
                     /gene="plsY"
                     /locus_tag="ACL8CG_001888"
     CDS             11346..11987
                     /gene="plsY"
                     /locus_tag="ACL8CG_001888"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGS1344432.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3461 a         2726 c         2124 g         3716 t
ORIGIN      
        1 ttcaaaaaac ggatttttat cgctttgaac atcaaaaaag aaaggacgaa atttgtcctt
       61 tctcgagctt agcttttttc aacccactac agttgacaaa gagccgaaaa atcccttgtt
      121 tagtaaacaa aggattttgt gaattttcaa tttgattaaa gttcgatatc accaaacaaa
      181 tcagccattg aaaatcctgt ttgtgtttct ggaagttcga aatcacgctt ttcttgacgt
      241 cttggacgac gtggacgagc agtacgtttt tcttcttttt gtccttcttc ttgggctgga
      301 cgttcttcaa gagctttaat agaaagtgat acgcgttctg catctgcgtt aacttcaaga
      361 actttaactt gaacttcttg accaacttta agagcttctt ttggattttc aatccgtttg
      421 tgtgaaattt gtgatacgtg aacaagtcca tcgatacctg gcaatacttc aacaaatgca
      481 ccgaagtcag tcaaacgttt aactgttcct tctactacat cacctttagc caatttttgc
      541 tcaacgccat cccatggtcc tggtactgtt gctttaagtg aaagtgatac acgtccttct
      601 tcttcgttaa gatcaaggat tttcacttca atttcttcac caacagttac aactgatttt
      661 ggtgatacgt tacgttcatg tgacaattca gtcaagtgaa ccaatccgtc aacaccacca
      721 aggtcgatga aagcgccgaa gcttgtgata cgagcaactt taccagttac aacatcacca
      781 acagccaatt taccgaatac ttcagcgcga gctgctgcag tagctgcttc aacaacttca
      841 cgacgtgaaa ggatgaagcg gttttcttta gcgttaactt ctttgatttt agtatcaaat
      901 tcttgaccta caaaacgctc agcgttacgt acgaaacgag tatccaacat tgaagctggg
      961 ataaatccac gaacaccttc aaattctact gaaagtccac ctttaacggc acgcgttcct
     1021 ttaacagtaa caacttcttc ttcgcgacca acaagtttgt cccatgcttt gcgagcttca
     1081 aggcgttttt tagatacaag gtatgtaact gtatcagtat ctttaccaac tacttgacga
     1141 agtacaagaa catccaatac ttctcctact ttaacaaagt cattgatatc tgcatcacga
     1201 tcgtttgtca attcgcgaag agtcaagaca ccttcaacac cagttccaga gattgcaacg
     1261 ttagcttgag tcgcatcaac tgtcaatact tcagcactaa caacatcacc agtctcaact
     1321 tgactaacgc tatttagcaa atcttcaaat tcgttcatct aaaaaatcct ccaacaatca
     1381 agtttttctt aaacttgaca tacttataat ttttttccta agcacccgca aggacatgtt
     1441 catatcattc acgtctttca attataaaaa taaaataccc taagatattt tgctttttat
     1501 cttgattatt acctaagaac tggggtagct ggattcgaac caacgcatga gggagtcaaa
     1561 gtcccttgcc ttaccgcttg gctatacccc attaatgaaa tggagagaga gggattcgaa
     1621 cccccgaacc cgaaggagcg gatttacagt ccgccgcgtt tagcctcttc gctatctctc
     1681 ctacaatcaa catggactat tatatcatga aaatttcaaa aaaacaagac ttattttgct
     1741 aaattataat tttcaatcaa aatttccaca gctttttcca attttttata aaaactatcg
     1801 acattcccat tctttataat ggcaaattgt ccgtctaatt cggcaatttc tccgataact
     1861 tttttaccga tagtcaatgt ataaccttca aaactgtctt taccaacatt aactttggca
     1921 tccgctactt gaatttcgat ttttttatct ttcttgctca tttcatacct ctcttcactt
     1981 tttctatttt acaagaaaat cctaaaacta gcaagaaaaa actctatatc aggcttctct
     2041 gatatagagt tttatgtaaa caacctcaat cgatttagca tagctaatag ttagtaaaca
     2101 agcataattg actatccttt ctaggttatc agtgagtctc accgcctact aactgcaaat
     2161 ccttatcttt gtagtctaca atagcttcaa tagctacctc tatgcctctt acaatatcac
     2221 atagactcat tcctgcagta ttcggcttat ttactacttg ttccatcata tatggaatat
     2281 gcatgaaacc tgctctcata ttagggaatt ttttatccac taaataaaga gcttggtaca
     2341 tcaaatgatt gcaaacaaag gttcctgcac tattggatac aactgccgga agtccctgtt
     2401 ttttgatagc ttgtaccatc gctttgatag gtaaactact aaaataggcc gatgctccat
     2461 caatacgaat cggtgtatca attggttgat tgccttcgtt atcaggtatg cgagcatcat
     2521 cttgattaat agccactcgt tcaggtgtta agccggtcct gccgcctgct tgtccaatac
     2581 aaagtacagc atctggttga tatcgtaata tttctgcctc taaaacttct gacgacttat
     2641 aaaaaaccgt tggaatttct acccagcgaa cttcagcccc attaatctca gatggtaata
     2701 attttacagc ctccaaagct ggattaatct tttcacctcc aaaaggatta aaacctgtaa
     2761 ccaatatttt cattttattt tcctttacta aaatgcgaga aagtacatta agaatatgtg
     2821 aataacaatc attactagag caacacctgc ttgagccttt ataacgccat tctgatcttt
     2881 catatccatc aatgctgctg gtagagcgtt aaaattagca gccattgggg tcaataaggt
     2941 cccacaataa cctgctgtca tggcaagagc accagccaca attggattag ctcccagagc
     3001 aaatacaaag ggaactccaa cacctgctgt aataacggtg aatgctgcaa aagcatttcc
     3061 cataatcatt gtgaatagaa ccattccaag aacataggcc aaaactccta taaagcgact
     3121 atctgaagga acaataccgc taatcagatg agagataaca tcaccaacac ctgctacagt
     3181 aaaaatagcc cccaaagccc ctaataattg aggaacaata ccacttgttg aaacttgctg
     3241 agtcattcga ttattttctg ataacagact cttagggtga ctattggtaa tcacaagaac
     3301 agaaattgta gcaaacaagg cggcaaggct aatcgaaatc ttgctaaatt ctggaatcat
     3361 ttgcgctaag accaacgcaa gtattgccat cagcataact ggaataaaaa ttttattttt
     3421 caacctgtta gattcaatat tggctttcat ttcatctaag gatggcaagg ttccgatacg
     3481 gacttgctta aacaatgtta acagcgataa taggattaca ataataccaa tactcatatt
     3541 tggcatatag gaaccaccta taaacgtaat agacaataga gtccaaaatg cagatgtccc
     3601 aagtcgaact gggtttgttt tatctttata actacaatag gctgtatgga gaaattgaca
     3661 accaatcaca atataggtca actctaatag ttgctttgcc aactctgtca tttttgttct
     3721 cctcccctag tcttttttga tatcaatttt ttatcaaata aataattgta aatccccact
     3781 acaataagtg ttataacagc aacaataata gatgtagaag caatccctgc ataattgctt
     3841 tcatagccta actgatctaa tgttccccct atcaagagga ctcccccagc acctacaaac
     3901 gtattttgag caaagaaatt tccaaaattt tcattcgctg ccgcacgcgc ttttattgtc
     3961 tcatcttcaa cctctgttaa ctttctacct aattgagact ctgcagctgc ttctcccata
     4021 ggctgaacca aaggtctgac aaactgaggg tgtcctccta gacgaattga aaagaaacca
     4081 gctaactctc gaataaagaa ataaactgta tagaagtttc caactgtcag acctttaatc
     4141 tttcgaatca aatcgattga tcgttgcttg agtccaaagg tttctgacag ccccacaaga
     4201 ggcaaggtaa ccataaaaat cgtgagcact cgctgattgc taaattcttt tcccaaaatc
     4261 tccaaaaatt caacgagaga aacacctgaa actaaagctg taaccaaacc agctaagact
     4321 actgttgcaa ttgtatcaaa ttttaaaata aaacccacaa caatgattgc tattcctatt
     4381 aatctaatcc actccatatc aaactccttt atattcaaaa tgacagtatt tttaaaattt
     4441 tatcaagatc aataccattc cttatttaat gtgtttttct agttcttttt ggtatttgct
     4501 attggattcc aatttttctt tttgccattt tttaaaaacc tcgttatatt cttttgttgt
     4561 aacaatatct ttttgcaatt tcattccttt aaagatatat ggatccccct taataccaac
     4621 ttgtgagtat ggttttgaga atggtactac gttacttaca actggagaac caccagatga
     4681 agctgttggc atcaataatg aactatctgt cgaccaagct tgagctttgg catatttttc
     4741 atatctcttc tctaggtcag tggtctcaga aacagcatct tctaacaatt tcttatattt
     4801 atccaaacca ggtttagcta caacatcctt atcttttcct ttcgtaatac caaggtgttt
     4861 catggcagaa ccagattttg gatccataat attcaagtaa gacgctggat cttgatagct
     4921 tggagcccat cctgtactat tcaaatcata gtctttttga gaaggagcaa cattgccgta
     4981 tttatcattt tccatcaaac catcaataac atttccaata acgtctgtcg tcgatgttcg
     5041 agtcgctata ctgtagccca atgatgctgg atctactgca tagacataag aaaatgttgt
     5101 cggtgcatcg gcttctttat cagtttttcc acaagccact aaaatagctg acgtgctcag
     5161 gaccactcct gctgttaaga gccacttttt ctatttcata aaaaatctcc ttcggtttat
     5221 tttaatctac ttttacaatc caaccttctg gcgcttcaat atcgccaaac tgaatacccg
     5281 tcaattcatt atataattta cgcgtcacag gacctacttc tgtttcacta tagaatacat
     5341 ggaaatcatc accatgttga atacctccaa ttggagaaat aaccgctgct gtaccacagg
     5401 cacctgcctc tacaaaacgg tcaagattat caattggaac atcaccctca ataggagtta
     5461 atcccaagcg gtgttctgcc aaataaagca aggaatactt ggtaatagat ggcaagatag
     5521 atggactcaa tggtgttaca aattcattat cagctgtaat tccaaagaag ttagctgatc
     5581 cgacttcttc aatctttgta tgagttgatg ggtccagata gataacatct gagaaatgac
     5641 gtgacttggc catttttcct ggtaagagac ttgcagcata gtttccacca accttagccg
     5701 cacctgtacc atttggtgct gcacggtcgt actcatcctg aatcaagaag ttggttggga
     5761 ccaaaccacc tttaaagtaa tttccaactg gcatagcaaa gatggtgaaa atgtactctt
     5821 ctgccggttt taccccgata atatctccga caccaatcaa aagagggcga agatataagg
     5881 ttccacctat tccgtatggt ggtacgtatt cttcattcgc acggacaact gctttacaag
     5941 cttctacaaa catgtctgtc ggaacttgtg gcatcaagag acggtcacat gtacgttgca
     6001 ggcgtttagc attttcatca ggacggaaca gttgaacact gccatcctta gtacgataag
     6061 ctttcaaacc ttcaaatgct tgttgtccat agtgaagact tggagaagac tctgaaatat
     6121 gcaaagttgc atcctctgta agctctcctt gatcccattg tccatttttg aaatgagcaa
     6181 gatagcgata aggtaatttc atataggaaa aaccgaggtt ttcccaatca atcgttactg
     6241 tcatattcca ctccttattc taaaaaccta tttcttatat tctacactat ttttctaaaa
     6301 tagcaagtat attttgtaat tttcagaaaa tttctccaat aaaaaccagc tcttagaact
     6361 gattcttcat ttcacttatt tatcttcagt aactacttcc tgaagataag cgtcaaaaac
     6421 ttcttcatct gaaatcgtgt cagaaatgaa gcttccattg ctagtgcgtt ctgacaagtt
     6481 caagtcttgc aatcggcttt catagattgt tcctttattg gattggacaa gcagagtttg
     6541 gtcgttcaca tccacttccg tactgaagaa atcgccaaca aatccttgct ctgcaactgc
     6601 tcctgccaag aagacacgat gcggtttgtt tttcaactca cgcaagactt gtaatcctcg
     6661 tttggcacgg ctggttgcta gaatttcctc aatggaaaca cgtttcaagc ttccacgctg
     6721 ggtcaagagg tagaaggacg aagtattaca gataaagcca gattggagga catcatcttc
     6781 tttcaaattc atagccttga cacctgctgc cttagcaccg acaaccggaa cctcttcgat
     6841 attgaaacgc agggcataac cattttgact aaccaagaca acatcatcta gtttaatcgg
     6901 agccactgct acaatctgat ctgtatcgtc tttgagctta gcatacttga cagacttaga
     6961 tctataggtc cgccatggag taaattcttt tcgctctacc cgtttgattt gaccaaggcg
     7021 agtcgctgca aagtaggttg tcgcatcgtc aaactgatcc agtacttcca cataaagaat
     7081 ttcttcattc gtttcaaagt ttgtgatggt ttggctcaga tgctctccga tgtccttcca
     7141 acgaatatct gccaactcat ggattggtct gtagatgaca tttccaagac ttgtgaacat
     7201 caagaggtgc tgggttgtct tggcagattg aacaaaaatc aaacggtcat catcacgctt
     7261 gccaatttct tccaaggtgg aagccgcaaa ggaacgtgga ctggtacgct tgatgtaacc
     7321 tgccttggtc acgctgacgt aggtatcttc ctcagcgata agactagctg tatcaatctc
     7381 aattgctttc gcagtatctt ctaaagaact caaacgagga gttgcaaatt tcttcttgac
     7441 ctcacgaagt tctttcttca tgagattgta catagtcctt tcatcaccga taatagccgc
     7501 cagcatagca atcttctcac gaagctctgc ttcttcttcc tgcaagacaa ccacatcggt
     7561 attggtcaaa cggtacagtt gcaaagttac gatagcctca gcctgttctt ccgtaaaatc
     7621 atagctaact ttgaggtttt ccttggcgtc cgccttattc tcagaagcac ggataagagc
     7681 aatgacttca tccaaaatcg aaatcacacg aatcaaacct tcgacgatat ggagacgttt
     7741 ctcagccttt tctttgtcaa agcgtgaacg cgccaaaatc acttctcgac ggtgagcgat
     7801 gtagctagac aggattggaa caatcccaac ctgacgaggt gtgaaattgt caatcgccac
     7861 catattaaag ttgtagttga tttgtaggtc ggtgtactta aataagtagt tgagaacaag
     7921 ctcagtatta gcgtctttct taagttcgat agcgatacga agaccatcac ggtcagactc
     7981 atcacgaacc tcagcaatcc cagctacctt gttattaaca cgaacatcat cgattttctt
     8041 gactagattg gccttattga tttcataagg aatctcagta ataacgattt gttccttacc
     8101 accttttagc ttttcaattt cagtcttgga acgaacaacc acgcgccctt tcccagtctc
     8161 ataagctttc ttgatttcat cacgaccctg aataatagcc cctgtaggga agtctggtcc
     8221 aggcaagaat tccatgagtt tatcaatctt tgcagttggg tggtcaatca tgtaaactgc
     8281 agcatctatg acctcagcta aattatgggg aggaatgtct gtggcataac cagccgaaat
     8341 cccagtcgaa ccattgacca agaggtttgg aaaggctgct ggcaagaccg ttggttcttt
     8401 ctccgtatcg tcaaagttcc atgcaaaagg aactgtattt ttctcgatat cctgaagaag
     8461 gtagcctgca atttcagaca aacgtgcctc agtataacgc atagccgcag gaggatctcc
     8521 gtccatagaa ccgttattac cgtgcatttc aactagaatc tcacgatttt tccagttctg
     8581 tgacatacga accatggcat catagataga agaatccccg tgtgggtgga aattccccat
     8641 gatgttcccg actgacttgg ccgacttacg gtagctcttg tcaaaagtat tgctatcctt
     8701 attcatagaa taaagaatac ggcgctgaac cggcttcaac ccatcacgaa tatctggcaa
     8761 agcccggtct tgaataatgt acttggagta gcgaccaaag cgctctccca tgatgtcctc
     8821 cagggacatg ttttgaatgt tagacataag atacaaagcc cataaaatac caagtgaaaa
     8881 tagaaaattc ttgaagtaag caaactcaca agagaattta tctttttcac acagtatcta
     8941 gggcgtgttc aactcctttc aaagaatgta gagtaggttt ttatgcagta aaagatattt
     9001 tacgggaatt cgtcccgtgt tcagttacga taagtaacca aactatcctg tttgtatttt
     9061 tcaatatgaa aatctggttt tccaaaatta gtcttagttt gtgtcttagc cgctccctta
     9121 aacgcctctt tgagataagc actcatagaa gattcttcat taataatcct gcaatttttt
     9181 caaaccaaga ttttcaaact gcttttttac atagtcattc acatccgact ctaatttcca
     9241 gtttactaac atattatttt ctttcattaa aacactgtcg cttcttctag cgtaaacttg
     9301 acattatctt caatccattt acggcgtggt tctaccttat ctcccatgag aacattgacg
     9361 cggcgttcgg cgcgcgctaa atcttcaatt gtgacacgga tgagggtacg tgtttctggg
     9421 ttcatggttg tttcccagag ctggtccgca ttcatctcac caagtccttt gtatcgttgg
     9481 agggtagcgc ctttaccgaa ctgtttacgg agttcttcta gttctccgtc cgtccaagcg
     9541 taggccactt cttctttctt gcctttacct ttggacatct tgtaaagagg tgggagggca
     9601 atatagacat gacctgcctc gactagcgga cgcatgtaac ggtagaaaaa tgtcaagagc
     9661 aaggtctgga tatgggcacc gtcggtatcc gcatcggtca tgataatgat cttatcatag
     9721 ttggcatctt caatagagaa gtctgctcca acacccgcac caatggtata aatcatggta
     9781 ttgatctctt catttttgag gatatccgcc atcttggcct tggctgtatt gacaacctta
     9841 ccacgaagag gtagaatagc ctggaacttg cggtcacgac cttgtttggc agaaccaccg
     9901 gcagagtccc cctcaactag atagagttca ttcttagcag gattcttaga ttgggctggg
     9961 gtcaatttcc cagacaacaa gcccttatct ttcttgtttt tcttcccatt tcggctctca
    10021 tcacgcgcct tacgtgctgc ttcacgagca tcacgggcct tgatagcctt gcggatgagg
    10081 ttagaagcta attccccatt ttccataagg aaaaaggtca acttatcagc cactattcca
    10141 tccacaactg ggcgagctag ggggcttcct agtttatcct tggtctgtcc ttcaaactgc
    10201 aagtgttctt caggaactaa gatagaaaga acggccgcta gtccctcacg atagtctgaa
    10261 ccttcaaggt ttttatcttt ttccttgaga agacctgttt tacgtgcata gtcattcatg
    10321 accttggtaa tggcagactt gagtcctgtc tcgtgcgttc caccgtcctt ggtgcgaacg
    10381 ttattgacaa aggatagaat gttatctgag aatccgtcat tgtactggag ggctacttcc
    10441 acttgaaaac cattgtcttc cccttcaaag taaagaactg gcgtcaagat ttccttatct
    10501 tcgttgagat aagaaacaaa atcttgtact ccattctcat agtggaactc aatcgcttca
    10561 tctgttcgct tgtccgttaa agacaaggtc acatttttca agagaaaggc tgattcatta
    10621 aggcgctctg aaatggtatt gtacttgaaa tctgtcgtag aaaagatagt cgcgtcaggc
    10681 ataaaagtaa ctttggtgcc tgttttagac ttgggtgctg taccgatttt cttcaaagtc
    10741 gtgacaggtt ttccaccatt ttcgaaacgt tgcttgtaaa ctgcgccatc acgggtaatt
    10801 tcaacttcta accagctaga aagggcgtta acaacggaag aacccactcc gtgaagtcca
    10861 cctgatgtct tatagccacc ttgaccgaat ttccctccgg catgaagaat ggtaaagata
    10921 acctcaacag ttggaattcc catagcgtgc atacctgtcg gcatcccacg tccatggtct
    10981 tgaaccgtta gactaccgtc tttattgata gttacatcga tacgatcacc aaacccagac
    11041 aaggcttcat cgactgcatt atcaacgatt tcccaaacta ggtgatgaag accagcgcca
    11101 tcggtcgatc caatatacat ccccggacgt tttcggaccg catccaaccc ttctagcacc
    11161 tgaatagcat catcattata attgttaata ttgatttcct tttttgacac aaggaacctc
    11221 ctattcgttc atctttacta ttctacaggt tttccaagga ttttgcaaaa tttttctttc
    11281 tccgatgtga caatttcagc agagattctc tgcttttctt tcccaattca tgatataata
    11341 ggagtatgat tacaatagtt ttattaatcc tagcctatct gctgggttcg attccatctg
    11401 gtctctggat tggacaagta ttctttcaaa tcaatctacg cgagcatggt tctggtaaca
    11461 ctggaacgac caataccttc cgcattttag gtaagaaagc tggtatggca acctttgtga
    11521 ttgacttttt caaaggaacc ctagcaacgc tgcttccgat tatttttcat ctacaaggcg
    11581 tttctcctct catctttgga cttttggctg ttatcggcca taccttccct atctttgcag
    11641 gatttaaagg tggtaaggct gtcgcaacca gtgctggagt gattttcgga tttgcgccta
    11701 tcttctgtct ctaccttgcg attatcttct ttggagctct ctatcttggc agtatgattt
    11761 cactgtctag tgtcacagca tcgatcgcgg ctgttatcgg ggttctgctc tttccacttt
    11821 ttggttttat cctgagtaac tatgactctc tcttcatcgc tattatctta gcacttgcta
    11881 gtttgattat cattcgtcat aaggacaata tagctcgtat caaaaataaa actgaaaatt
    11941 tggtcccttg gggattgaac ctaactcatc aagatcctaa aaaataggct ctttgtcaac
    12001 tgtagtgggt tgaaaaaaag ctaagct
//
LOCUS       DBEROT010000052         9989 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.52, whole genome shotgun sequence.
ACCESSION   DBEROT010000052 DBEROT010000000
VERSION     DBEROT010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.52"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(122..571)
                     /locus_tag="ACL8CG_001889"
     CDS             complement(122..571)
                     /locus_tag="ACL8CG_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS1344433.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYNYIKTHRVS"
     gene            complement(573..1331)
                     /locus_tag="ACL8CG_001890"
     CDS             complement(573..1331)
                     /locus_tag="ACL8CG_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS1344434.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1446..3425)
                     /gene="stkP"
                     /locus_tag="ACL8CG_001891"
     CDS             complement(1446..3425)
                     /gene="stkP"
                     /locus_tag="ACL8CG_001891"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGS1344435.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIILTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3422..4162)
                     /locus_tag="ACL8CG_001892"
     CDS             complement(3422..4162)
                     /locus_tag="ACL8CG_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGS1344436.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4177..5490)
                     /gene="rsmB"
                     /locus_tag="ACL8CG_001893"
     CDS             complement(4177..5490)
                     /gene="rsmB"
                     /locus_tag="ACL8CG_001893"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGS1344437.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5483..6418)
                     /gene="fmt"
                     /locus_tag="ACL8CG_001894"
     CDS             complement(5483..6418)
                     /gene="fmt"
                     /locus_tag="ACL8CG_001894"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGS1344438.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6431..8827)
                     /locus_tag="ACL8CG_001895"
     CDS             complement(6431..8827)
                     /locus_tag="ACL8CG_001895"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGS1344439.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QESNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKVYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(8893..9207)
                     /gene="rpoZ"
                     /locus_tag="ACL8CG_001896"
     CDS             complement(8893..9207)
                     /gene="rpoZ"
                     /locus_tag="ACL8CG_001896"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGS1344440.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9232..9858)
                     /gene="gmk"
                     /locus_tag="ACL8CG_001897"
     CDS             complement(9232..9858)
                     /gene="gmk"
                     /locus_tag="ACL8CG_001897"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGS1344441.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
BASE COUNT         2680 a         2386 c         2021 g         2902 t
ORIGIN      
        1 gctttcgtgg ataccaaaat cagccgcaat ttcttcataa gtgcggtatt ctcgcacata
       61 tagaaagcgt tgttaattta tttatctcat ttttcagaaa attcttttat ttctgtaaag
      121 tctacgatac tcgatgtgtc tttatataat tatacagtct gagaatcact gttccgctag
      181 ccattccaat agagattacc agagccaaca tgacaaccaa ggtcgcactt gccagtgctt
      241 tattatagtc ccctgtcaca aaaaaggcag ttgttcggta ggagagataa cctggaacca
      301 gcggtgccaa aatggccaag ataaagacca cagcaggtgt cttataaaga atacttaaaa
      361 tctggctgac acaagaacca ataatggctg caatgaaggt agctacaatg acattggtcg
      421 gttccttgag caagagatag attagccaga cagtcatgcc caaaatccct ccaggtaaga
      481 gcatagaccg ttgcacattg agtacgatta aaaaagtgat aatggcaaga aaacttgcta
      541 ctgcttgtaa taaaaaggtt gttagtgtca tattagttca tcaataccaa ggcgacagaa
      601 gttcctgccc ctaaagcgag ggtaatgagc agggattcaa acatcttact cataccagag
      661 tttatgtggt tggtcataat atcacggacc gcattggtca aggcaatacc tggtacaaac
      721 ggcatgaccg caccagctat aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc
      781 caaaactggg caattatccc aaagacaaag gctccagcaa aggctgtcac aaagggaatt
      841 cggataaatt tttccacata gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc
      901 ccaagtgcgt cgtagatatt tccgctaaac ataactgaaa agaaaggagc actaaaggtc
      961 gcagccagag ttacctgcaa cttagtatag ggaaggggtt gagcttgcaa ggccgtcaat
     1021 tgcttaaagg ctgtttctaa gtcaatctgc cccccaacta gctgacgaga aatctggttc
     1081 acatcgcaga ctttttcgat gttataagaa gaggaggtca cgcgcttcat gcgcgaaata
     1141 ttggtatttt caatagagaa aaagatagcg gcaggcatgg caaggacatt gcaatccaca
     1201 atcccctgcg aatgcgcgat tcgaatcatg gtatcttcta cacgatggat ttctgagcca
     1261 cttttaagga gaatagtccc cgctagcata atcacatcaa tgacggcatt taattctttt
     1321 gattcttcca tgctttcctc cttttatcaa ctccctctat tctatcacaa atctggactc
     1381 aaaaaaaatc tttgccatga aatcatgaca aagattgatt actcattttg attatccatc
     1441 tacttttaag gagtagctga agttgtttta ggtttgtaga ttgaaatctt gactctagtc
     1501 ttattgaggt ctaccttttc acctgctcta ggactttgtt caacaaccat gccttctgca
     1561 ctacctgcag gcgctgtcgt cacttctaca acttctatat tagcttcctt aatcccaaca
     1621 atttgaatca aattgttctt agtaaactcc aagctggaac caatgtaact cggcatggca
     1681 acacttgtaa cttttttagc tactgtcaag acaatttgag taggtttact cacatcataa
     1741 gtcgttccgg cacctggact ttgtttcata atcgttcctg gttcgctttc gctggactct
     1801 tcttcctcta tcttaatcaa attctcagga accttcttct gcttgagttc tgagattact
     1861 tctgtagagt tccgtccaat atagttccct aattgaatcg tcgtagcttt tttagctact
     1921 gtcaaaataa tttgagttgc cttgctcaag tcataggtcg taccttctgg tagactttgc
     1981 ttcaggaccg ttccagcctc actctcattc gactcttctt cctcaatttt aatcaaatta
     2041 tctggaactt ttttctcttt taattccgcg ataacatcag aagatttccg gccgacataa
     2101 ttactaattt ggaaggattg tttgcctgat gagacaacca gattgatttt cgttccttct
     2161 tttcgaccag ttccagcgcc aggatctgta cggataatcc gcccttcttc caccttttca
     2221 ctagcctctg tcttctcctc accaatctca aaattggctt ttttgagcgt tgccttggcc
     2281 tctgcaactg tctgacctgc cacatctgga atggcaatgg ttgcaggagt tctggatagt
     2341 atccaaataa gagaagctgc caccaataca aggctggcca acaaaatcag gtaacgcatc
     2401 ttaaatctat gttttttcgg tgcttgtggt tggtaagttt cctctgtcac agcctggctt
     2461 gggtttttga ttgatttgtg ttctgtctgc gcttgaacct taggaataga tgtcaaggta
     2521 ctctgagaaa ccttcggcaa ggtcttggta tctgccttgc tcgtttcatc aaagattaac
     2581 ttactttcat ttctacgatt gtaggacaag ctactagaca agtccacata catctctgaa
     2641 accgagcggt agcgattggt caacttttta gcagttgcct tgataataac attttctaaa
     2701 gcctgaggta cagatggatt ttctgcaata acggacggca ggggtttctg gaaatgctgg
     2761 agggcaatgg tcaccgcgct atccccgtca taagggatat ggcctgtcaa catctcatag
     2821 aaaataatcc ccatggcata gatatcactc tgcacagtcg ccttagaacc acgcgcctgc
     2881 tctggtgaca agtaatgaac tgagcccaac atcgagttag tctgggtcag acttgtctct
     2941 gcaaaggcta cagcaatccc aaagtctgtg accttggcag tcccatctgg tgtcaaaagg
     3001 atattttgag gtttcaagtc cctgtgaaca attcctcgag tatgggccaa gcgcatagcc
     3061 aagagaattt gtcccatgat acggactgct tcttcattag aaagaggata atgttccttg
     3121 atatagcgtt tgaggtccag tccagccaca tactccatag ctaggtactg ttgaccgtct
     3181 tcctcgccaa tatctgttat ccgaacgata tgaggatggt ctagatctgc catagctctc
     3241 gcttcacgct gaaaacgagc tacagctatc gggtccgtct ggtagttggt cctcagaacc
     3301 ttcactgcca cttcttcccc atctaagatt aagtctttgg ctaggtagac atccgccatg
     3361 cctcctcgac caatctgttt gacaatccga tagcgtccgg caaaaatctt gccgatttgg
     3421 atcattctgc atcctcctcg ttcatagaaa caagggcaac cgtaatgttg tctaaacctc
     3481 ctgcattgtt agcaaaacga acaagtgtct ccgttttatc tgctaaagga atatcactgg
     3541 ttacaatatc acgaatctca ctgcctgaaa tcatgttggt caagccgtca ctattgagca
     3601 agagatagtc acctgactca aggataactg tcccaaaatc aggctgaatt tcatcttttt
     3661 gcccaataga ctgggtgata atattttttt gcggatgagc ttctgcctct tctggtgtca
     3721 attgaccagc cttgagcaat tcattaacca aggaatgatc gctcgtcaac tgatggtatt
     3781 cttctccacg aatcaagccg atacgcgaat caccaatatg agcatagata gcctgattat
     3841 caataatagc aaggacttcc aaagtagttc ccatgcctct gtaagcttca tcctgaccaa
     3901 gctggtgaat cttttgattt tcaatttcta ggtaatgggc gaaccattca cgcacttcat
     3961 tgactgtatc gatctgagta tcaacccaag ctacacccag gtctgtgact gccatttcac
     4021 tagcgatatt ccctgcgcga tgacctccca tcccatcagc taaaataatc atggtacgtc
     4081 cagctctatt gacatagtgg ttgacatagt cttggttatt tgttcgtttc tgaccaacat
     4141 ctgttaataa tgaaatttcc atgtgtcagt tccttcctaa tccgatatct tgcgaaattg
     4201 actgatgaag aatccatcac ttccatacaa ttcaggtgta atgaggatac agccgtcttt
     4261 catgatatcc ttacattcat gttctagttt tacctgctcg aactcgggat gactctctaa
     4321 aaaggcctta acgacttgaa aattctcctc tgagacgata gtgcaggtgc tataagttat
     4381 tataccacct ttgcctagta tttgacaaac actacctaat atttctaact gaatttcctg
     4441 caaggacgcg aaatctgccg tttctttatt gtatttgata tctggttttc ggcgcaaaag
     4501 accgattcct gaacaaggag catccaccaa aatcttatca aaggaatcct ggtcaaaaaa
     4561 ctcatgcacc tttctggcat ccaatttttg agtttgaacc cgatcttcaa ctcccagacg
     4621 ttgggcattt tcttgaatta aatccaactt atggtcgtac aagtccagag cagtaacctg
     4681 acctgtcgta agataagagg ctatatgggc tgttttccca cctggagccg cacaggcatc
     4741 aagcactcgc tcatcacctt gtaaatcaag cgtcggagca accagctgac tggactcatc
     4801 ttggatggta atggctccat tcgcaaacaa attatgccct gcaaaatgcc cctgctcctt
     4861 aaccagacca gtggttgcta aaagggaatt attcgcctcc aacaaggctt ggatttcctc
     4921 ttttcgactt aggtctgtta cacgaatact ggctttgttt cgcactaaca ggctttcaaa
     4981 gatggctttt gctctctcct ctccgtattc ttccttgagt ttggcaacta gccaaactgg
     5041 gagagaatag gcaatggagt cacgcttgtt ttttcgcttg atgctagcaa tatctggcca
     5101 gccttcacgc aagatacggc gaaggacagc gttgaccaat ttttcactgc cttttttacg
     5161 gagtttggcc aattccactg cttcattgac cacagcatga tctggaatct tgtccaaata
     5221 gcggagttgg taggcactca tgagaagaag gacatagagc cagctgtcta actggtctct
     5281 gtcttcgata aagtgggata ggtaccattc cagagtcagt ttacgggcta ccgttccata
     5341 gactagctcg gtcactaagc ccttgtctgc tgcagagagc tgactcccct tgaggtgttt
     5401 atttaaggca atatttgaat atgcttgatt cacaaaaaca tcctctagca ctgctagagc
     5461 taaacttcta gccgtttcta ctttagtcac caaatcgttc tcctacagtc aatgtacgtc
     5521 caactccgtt gaggaaggaa gcaatgtcca tcttaggctt accagctggc tgcacttgtt
     5581 tgagggatag agccccttca gccgttgcga caatcaattc tttcttgcag atagagagaa
     5641 tctcacctgg atttccctga ccttctactg gtagggcttc ataaatctta aagcggtcgc
     5701 ccttaaggaa agtatgggca acaggccagg ggttcattcc acgaatttgg ttaaagagtt
     5761 gacgattggt tttgttccag tccagttttt cttcctctgg ctttatattt ggagagaagg
     5821 taacctgact cgtatcctgc ggttcaggtt tgatatcacc agcaatatag gcaggcagag
     5881 tgtccaaaag caaatcacga ccaactagcg ccaatttttc aaacaaggtg ccaacattgt
     5941 cctcatctgt gatcggaatg ctgcgacgag aaatcatatc tcctgcatcc atttccttaa
     6001 ccatttccat gatggtcaca ccagcttcct catccccttg aatcaaggca taatggatag
     6061 gcgcaccacc acggtgtcta ggaaggaggg aggcatgaac gttgacagca aagtccatgc
     6121 tatcaaggag tttgcttggg agaaactgcc caaaagcagc agtcacaatt ccatctgctc
     6181 ctagcttcat aagttcttcc atctctggac ttccagataa tttttcaggt tggtagatag
     6241 atagtcctgc ttccttggca gcctgcttga ctggggtttc ttggataact tttttacgac
     6301 caacagcacg gtctggctgg gtcacaacgg ctagaatttc gtaacggtca tctgtcaaaa
     6361 gtccttttaa gactgttgct gaaaagtcgg gggtccccat aaagattagt tttgtcatat
     6421 cttctccttc ttataaaaat tgctgcggct catggtcaat gctgagacgg agctcactat
     6481 tttcccgttc ttgagtcaag gctaaaacct ggttgagggt cggccccagc tcatcttcta
     6541 aacggtattt aattaaaatc tggtaatgat agaggttgtg ggtacgggca atcggttttg
     6601 gcgttggccc cagaatggga ctggtctctg acaagcctga ccgcaaaatg ttcatgactt
     6661 cataggcacg tttgaaaacc tcttcttctt tcttgtgaga aagggtaata ccaatcgtga
     6721 aatagtaagg tggatagccg agttgtcgtc tgattcccat ttcataggca taaaagcctt
     6781 cgtaatcttg atccttggca aatcgaatag catagtgctg cggattgtag gactgtatca
     6841 agacttgacc tgccttttca gcccgacctg ctcgacctgc cacctgagtc aagagctgga
     6901 aggttctctc agaagaacgg aaatcaggca gattcaaggc cgtatccgca tttagaactc
     6961 cgactagggt aacattggga aaatccaaac cctttgcaat catctgagta ccaagtaaaa
     7021 tatccgcttc ccctcgccca aactggtcaa gcaaggcttg gtgactgcct ttctttcgag
     7081 tcgtatccac atccatcctc agaatgcgag cttggggaaa gagttctgct agctcatcat
     7141 aaaccttctg agttcccgtc ccatagtaac gaatactgtg gctcttacag ttaggacaga
     7201 cctgaggaat atccttcgag aaaccacaat aatggcagtt catagtcttg gtatccatat
     7261 gcaaggtcag agaaatatcg cagttgggac aagtatccac cgtcccacac tcccgacaca
     7321 tgacaaagct agaataacca cggcgattga gcatgagaac cacctgctct tttttaacca
     7381 gacggtcttg gatagcctct agcaaaggag gcgtaaagtt tgacgtctca ttttgtccga
     7441 tatagtctcg aaagtcaatc acttgaacct cagggattgt agccaaagga ttggcacgtt
     7501 gggttagacg taagtgttga tagacgcctt tgccagcacg cgcccggctc tctaagctcg
     7561 gcgttgcaga tccaagtacc agagttgctt gattatactg agcccgtaaa atagctacct
     7621 ctctggcatg gtaacgggga ttgctttcct gcttataagc cgcttcatgc tcttcatcaa
     7681 taatcatgac acccagattt ttcagaggag caaagatagc agatctggca ccaacaacaa
     7741 cttgggcatc gccacgctcc accttgcgcc attcatcata cttttcacca ttggataatc
     7801 ctgagtgaag aatggctacc ttgtccccaa agcgtgctat aaaacgctcg gtcatttgag
     7861 gagtcaagga aatctcaggt accagcaaaa tagctgtctt gcccttatcc agggcacctt
     7921 ggataatctg caagtaaacc tcggtcttcc cacttcctgt aatcccttga agtagaaagg
     7981 gaggttgaga actgccaata gaactcacaa ccgcatcacg cgcctgtctt tgttctggat
     8041 ttaactccaa aggtctactt gcttcaattc cttcaaaata agcagccgag cgttgaactt
     8101 ccttttggac tatggtaaca gcaccttgat ccacaaagaa gttgacttgc tctcgcgagt
     8161 aggactccaa caagctagcc aaggaagcgc tctctggatg agacagcaga taatctctca
     8221 gttccaactt tttcttggca cgtgtagaaa tctcaacacc ttctaattga gcatggtcaa
     8281 cctcatacca agactgggtc ttgaccttct tttgatcgac tgcctgatat tccagaccaa
     8341 gcaggccttt tctagtcaaa cgcatcattt cagcttgctt acctaaatcc agagaagaaa
     8401 aggctagcga atcttctgaa ccaaacaggc gtactcgttc ttcctgactc aagccttcca
     8461 gaggatagag aatcttgtca tagctagaat tcagaaatcc cggaagcatg gccttgagga
     8521 tagagatttt gtaggagaag acagatttgc gtaactcctc agccagccag agttgttctg
     8581 gcgtgagaac aggagaaaaa tccagcacct ctgcaatatc ttttaaatct tgctccatct
     8641 cttctccatc tgattgggac tccaaaccaa gaacaatccc ttgaatcagg cgattaccct
     8701 taccaaaagg cacatgaacc cgcatcccaa cttccagcat tccctcaaat tcctccggaa
     8761 tcctgtaact atagggctgg tccgtctgca tcaagggcac atctacgata atcttagcta
     8821 gggccatctt ctcacctcct ccttgtcagt acattcttgc aatagaaaaa ataagattga
     8881 gtccccccaa ccttaaattt tttcaccatc ttctttttct ttagcaattt gctctttgat
     8941 tttcttttct tcttcttctt tgcggcgttt ttcttcttcg atacggcgac gcactgcttc
     9001 acgttttcct tctggatctg ggtgaattgt aacgtttcct gattcgattt cttctaaagc
     9061 gcgaagagtt gatttttcag acttgaaacc ttgagttgct ggggcacctg cttccaattc
     9121 gtgggcacgt tttgcttcca agattacgag tgaatatttt gaaggaacct tgtcgagcaa
     9181 ggtatcaata gagggtttta acatcatttg cttgtaccta ttttctaaat tttatcgggt
     9241 agttggagat tttggtaaca tctcctgata gtgaccaatg acacgatcca cacagaagtg
     9301 ttctgcttca atcacacatt tgacacgttc agcagctagg ggcacctgat cgttgacaat
     9361 cgcataatca tactcacgca tgagggcaat ttcttccttg gccttttcga ttcgttgggc
     9421 aatcacttct gcactatctg ttccacgacc taccaagcga tcttgcaatt catccaaatc
     9481 tggtggtgtc aggaagataa agacagcatc tggaaccttt ttcttgacct gaagagcacc
     9541 ctgaacttca atttcaagga aaacatcgat tcccttgtcc aaggtttcat tgacataggt
     9601 cagaggagtt ccatagtagt tgccgacata ttctgcgtat tccaacatct gtccttgacg
     9661 aatcagctct tcaaattctt cacgagtacg gaagaaatag tcaacaccgt ccacttctcc
     9721 aggacgttgt gcgcgtgtcg tcatcgatac agagtattga aattggtttt cagaactctc
     9781 aaaaatctct cttctaaccg ttccttttcc aacccctgaa ggaccagaaa aaacgattag
     9841 taagcctcgg tctgccattg tgtctccttt tagtcaatct gtgaaataac atttctctag
     9901 aataatggca aaaagccaga ttatccttta cagtctttct atctagtgta acaaaaaagc
     9961 agtaattttt caactgctct ttcttattt
//
LOCUS       DBEROT010000053         9963 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.53, whole genome shotgun sequence.
ACCESSION   DBEROT010000053 DBEROT010000000
VERSION     DBEROT010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.53"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="ACL8CG_001898"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="ACL8CG_001898"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGS1344442.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="ACL8CG_001899"
     CDS             complement(1995..2927)
                     /locus_tag="ACL8CG_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGS1344443.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="ACL8CG_001900"
     CDS             complement(2924..3781)
                     /locus_tag="ACL8CG_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS1344444.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDENKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="ACL8CG_001901"
     CDS             complement(3785..5131)
                     /locus_tag="ACL8CG_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1344445.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="ACL8CG_001902"
     CDS             complement(5144..5428)
                     /locus_tag="ACL8CG_001902"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1344446.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="ACL8CG_001903"
     CDS             complement(5432..7462)
                     /locus_tag="ACL8CG_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS1344447.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="ACL8CG_001904"
     CDS             7653..8660
                     /locus_tag="ACL8CG_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS1344448.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALKRLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="ACL8CG_001905"
     CDS             8663..8863
                     /locus_tag="ACL8CG_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1344449.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="ACL8CG_001906"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="ACL8CG_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGS1344450.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="ACL8CG_001907"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="ACL8CG_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1344451.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9854..>9963)
                     /locus_tag="ACL8CG_001908"
     CDS             complement(9854..>9963)
                     /locus_tag="ACL8CG_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS1344452.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         3230 a         2112 c         1609 g         3012 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaaatac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tatcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatat tagcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacgaagg catccacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgatgatg tcacgagatg ttagagagaa acgcatacca ggtgttccca
     1501 tagcgatccc gtccgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ccgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcatagatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta atgtaatttt tacagaaatt ctttcagata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc gaatctttct
     2101 tgaaccccca tccgatgaat ttttgttatt ccatcatcag agaataattc acataaagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgag
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tataccagaa
     2341 gcaacgatta caagatcttc cccgtgtctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattgaatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cccttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgga ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tctcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccttcattt aactcaccat ctccaacaat agcataagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aaaacttcta
     3661 cgatagacag acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta actcatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccgagtc
     3961 ctcccaaaac tggcattaaa aagactggga gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aataacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaataaaac tagagataaa tccaattaga actgcattag
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catagataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc caccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagatgaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccattc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tatcattata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttggt aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatacca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaacg gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggtaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatcaatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg actattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaaatt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaacttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg ggttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcactg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga agaaatccaa agtcgtgttg aggatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaaa acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaagaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcactaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagttaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta catttttcac tacctttttt
     9481 gaaataagaa tacggattcg gacgattaaa agtaagagaa actcaaatgt aagttggggt
     9541 tccttttttg tatatttttc aaataacgcc tctacactat ttgtagcaaa ttcaccaact
     9601 acagttgtat cttagttaaa ataagttaga atatgtaagt gagtaccaga tataccaaga
     9661 catcgtcacc atctaaggta tattcaaaat acaaaagttg accaactaga tttctgaata
     9721 tccttatata tccattctta aaattggttt aaatagcgta gtcttttaaa ctagttttga
     9781 gaatccaaaa aatcttccta catatgtaag aagatttttt agttcagaat gattagattt
     9841 agctaatgga tacctatcct acccactcac cgttagcatt gactcgatag ccatcgggtg
     9901 tagtcgtgtt tactaataaa tctcctgaat tataggtata gtaccattta ccagaaactg
     9961 taa
//
LOCUS       DBEROT010000054         9949 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.54, whole genome shotgun sequence.
ACCESSION   DBEROT010000054 DBEROT010000000
VERSION     DBEROT010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.54"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            200..445
                     /locus_tag="ACL8CG_001909"
     CDS             200..445
                     /locus_tag="ACL8CG_001909"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS1344453.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(723..1493)
                     /locus_tag="ACL8CG_001910"
     CDS             complement(723..1493)
                     /locus_tag="ACL8CG_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGS1344454.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(1508..2356)
                     /locus_tag="ACL8CG_001911"
     CDS             complement(1508..2356)
                     /locus_tag="ACL8CG_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGS1344455.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGTPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(2353..3828)
                     /locus_tag="ACL8CG_001912"
     CDS             complement(2353..3828)
                     /locus_tag="ACL8CG_001912"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGS1344456.1"
                     /translation="MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(4151..5506)
                     /locus_tag="ACL8CG_001913"
     CDS             complement(4151..5506)
                     /locus_tag="ACL8CG_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1344457.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(5516..5833)
                     /locus_tag="ACL8CG_001914"
     CDS             complement(5516..5833)
                     /locus_tag="ACL8CG_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1344458.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5850..6167)
                     /locus_tag="ACL8CG_001915"
     CDS             complement(5850..6167)
                     /locus_tag="ACL8CG_001915"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1344459.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(6182..7078)
                     /locus_tag="ACL8CG_001916"
     CDS             complement(6182..7078)
                     /locus_tag="ACL8CG_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGS1344460.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(7075..8343)
                     /locus_tag="ACL8CG_001917"
     CDS             complement(7075..8343)
                     /locus_tag="ACL8CG_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1344461.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLEDCE"
     gene            8623..9801
                     /locus_tag="ACL8CG_001918"
     CDS             8623..9801
                     /locus_tag="ACL8CG_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS1344462.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT         3456 a         2087 c         1426 g         2980 t
ORIGIN      
        1 agtttcaatc tactatattt tcgtacaggt gcttcaatag tttctatagt aaaatgaacc
       61 aaaaatagta cacgttgcgg tataatgttc ttgtggcata ttcattagat tttcgtaaaa
      121 agttctctcc tatttgtgag cgaacaggta tagtcaattg attgtcagtt tgaagaccaa
      181 gagtcgtaag gcaaaggata tggcagaatc catccaaggg tggctggcac aatttctagt
      241 gaacctcttt aaatctatta cgtttgactg tggaaaagag ttttcaaaat ggaaagatat
      301 ttccaatcat cacgatagtg agagcttttt tgcgaatcta ggatgtccaa gacagcggtg
      361 tctcaacgaa cattcaaata gacttttaag gtgtcatgac ttgccaaagc agacagattt
      421 caacgaagtc agtcaagaat tttaggctgg gtaaaaactc aatttcagga gaaaatgaaa
      481 taaacattcc cacaataaaa cgcatagtat caaagttttt ccaacacctg atattataca
      541 ttttttaatt ttaaagactt tttcccagcc tcaagaaatc acatcccacc taaatccttt
      601 ggataccaaa tacctcatca ggtattttct gagttggtaa gactgtctag cttaatttga
      661 caaatggagg gcgttaaatc cagtttttac aggaagtcta tttaaatatt ttcacactga
      721 ccttacaaaa tatgaaataa attatataaa gtcattccca tgacaaagaa taacatccct
      781 ttaaaacagt atcttaccca attttcaggt aagacttttg atacaaccgt ccccaatacc
      841 cctccgcata tagaagcaag aaaaataact ggaacaggtg ctaaatgata ctgatttaaa
      901 cctgtaacca caacaattgt agccaaatga gacaactggg aaaagaaaat aattgcaaga
      961 gaatacatcg ttgcttcttt tatcgaaata gaaaaaaaca ccatcaataa agatacattg
     1021 agcggaccac caccaatccc taaaaaacta gaaatcaagc ccaatagaag accacaaatc
     1081 atatagaatc ctatcttatc aaattgataa gtttttttaa aatctgttaa aacaaatgat
     1141 acaagtagca tcacaaatag taaaatcatt tgaacaatgg atactagccg tactgataac
     1201 tgagataaca aaacttgaaa aataagatga cctagaaatc ctcctaaaac agaagaaaag
     1261 gataccgtaa aaatcaatct ccattttatc tctttacttt gtgaaaatct tttgattgtt
     1321 gaaataatcg ccattataaa aacagagaaa ctagaataaa aagcaatatc actgaccgaa
     1381 tggtatccaa aactatccat aagtggctta attataattc caccacccat gcctgatata
     1441 gaacccaatc cactagctat tataatgatt agaaaataaa taatctcaac cactttttaa
     1501 gtccatccta ttctttcaaa catctaaaac ctagatggct actagtggaa gtagaaatac
     1561 atccatttct agcagctact cggtatcgat tacaataaga acaatgacat aaaaaggaac
     1621 ctcctctgat agcatactcc tcatcttgta tcccatattt tggtaactca tagtcatctt
     1681 cattaaaact agctaataag gtatatctcg gattgcgaca ccattcccaa acattcccaa
     1741 tcatttgata tagaccaaaa tcattaggta aaaattcata gacaggagcc gttcctataa
     1801 atccatctaa ggcagtattt tcataaggaa atcttccttg ccaagtattg gcatgataat
     1861 atccaccttc taaaagagta tctccccaag gatattcaga ttgtcttcct cctctagcag
     1921 catattccca ctgtgcttca gtcggtaaag acattccgct ccaattacag aaagccaatg
     1981 catcttctaa agcaacatga actactggat ggtcttctaa acccactaga ttactattct
     2041 caccgtaggg atgtttccag caagcgttcg gaacttgtaa ccaccacgga gtcccagcag
     2101 gatgaggata tccctccctt tctgcctctg gaacgaacaa tataaaaaca aaagaccact
     2161 cttgtcgctc agctagtgtt ttatagcctg tttctttcac aaattgagca aattcttgat
     2221 tcgtaactgg agtatccgca atggaaaaat cctttacact aacagcgact tgaggacctt
     2281 caaaatcatc taaaaagccc tcttcagaat ttgttcccat cataaatgtc ccacccttga
     2341 tttttttcat tttcatgatt gactatcccc cgttttcgtt agagttggcg ttattttaga
     2401 aagttcaaca ggaactaact cttcatccac aacaaaacct tcttctctat atctaagaaa
     2461 gtctactaat tttttcttca tctgacgaac aataggttgg tatttttcac ttggatacaa
     2521 atcattcatt tcatgcggat cttttttcat atcaaataac tgataatgat ttaaaacagg
     2581 aaaccagata aatttccact ggtctgtcaa gatatattga ctagaatctt ttcctaaagc
     2641 atgttcacca tgaaattctg ttcgccaccc ctcgtactgt ccaaataata aattcttaac
     2701 actccgtcca tctagttcat ctgtagtagt tcctcctgcc aaatccacga gtgaaggaaa
     2761 aatatcttga attttcacta attgcttgat tgttccccta ttaccagcta tcaatccagc
     2821 cggatcgtaa ataaacgaag gaatgtggat acttccctga taaggatatc cctttctaaa
     2881 cagataatgt tcaccaagct gatctccatg atccgaaaca aaccagataa tcgtatcttt
     2941 atcatgacga aattctttta gggcagtcaa aaagcgacta atttgatggt ctatatgagt
     3001 aatcaatcca aaataagcag caaccattct tctttgatca tcttccttta atttccctct
     3061 taaagcataa atagacggaa tttgcttttc taatacttcc caattcccga tatgcaaatc
     3121 gagaaattga ggcaagcgtt ccatatacat atcaaaatag tattttgggg gatttaatgg
     3181 agcatgtggt ttttcaaaag acattttgag aaaaaaagga accgttggat ctcttctttg
     3241 taaaaatgaa atggactcac tcacaaccca gtttgttgga tgtaacttct catctttatc
     3301 ccaaggtcta gcttcccaag aattacaatc cattccgtca tcaatcaaat caacatcata
     3361 accaacttta ccctttaaaa aggctagata gtcactagca taatcaaatt gacttccata
     3421 agccttatca tactttctat caacatgtag atacccatcg tgaagtaaga catgatcaaa
     3481 cccaagtctc tgtctggaag gaaaaacatg catcttacca atacactctg tttgataacc
     3541 catatcttta aagacttttg gaagagtatt agtaaaattc caaggcacct catcttgata
     3601 accaactcgt ccacttttat cttggtctaa gccagtcaat aaagctgccc tagcaggaac
     3661 acaagaagga actggagaat aggcattttc aaaattataa cctacactag ccatcatatc
     3721 taatgttgga gtgctaacta gcttatcctt actattcaag gataagacgt ctgctctcat
     3781 ttgatctaca acaatcaaaa taatatttgg ctgttttgtc tgaaccataa aatctccttt
     3841 ctaatatggc aaaagaggca caagaagata tctaccttta ctgcacccct ttctatatca
     3901 atctctctat ataaaacaat aacattcttg ttatgtttta tagaaaaatg aactaaaata
     3961 tgactaaatc gattaggaaa ttcaaatcat tttctagtac tgttttagaa gttacagtgt
     4021 actattccaa cttcaataaa ttataaacct ttgtctaata acaattttag tggagataag
     4081 aaatcctaca cctaactcat cttacacgta atctatttct attttatcac aaaaaacgca
     4141 agtaagacca ttaactcaat tcagttttat ctgccatttt cacaaatggg aaataagtca
     4201 agacactaat aatcaaacaa acaactgata agatgatggc acgccaatca aatgctgtag
     4261 agaagaaacc atataaaatt ggaggcatta cccaagtaac gttttgtgta acaggtgaaa
     4321 caagacccca gcttgttgcc cagtaagcta ccgttgccat gaaaaccggg ctaagtacaa
     4381 atggtataaa tagcaaagga ttcaagacaa ctggtaaacc ataattgacc ggctcaccaa
     4441 tattaaacag aactggtgct agaccaagtt tagcaacttt tcgataatga ctgtttcttg
     4501 aaaaaattaa aatagcaagt actaatccta atcctccaaa ccagacaaac gccccaaaag
     4561 acccacttgt ccatatataa ggaatcggtt cacctttttg gaaagcatcc agattcgcta
     4621 acatagcaac tccaaacagc ccttccatga tgggagccaa tacatttcct ccatggagac
     4681 caaaaaacca gaataactta ttcaaaaaga tcatcagaat aactgcaaag aaactttgag
     4741 acaaacctag taatggcgtt tgtaacacct tgtaaaccca atcaatcaat aagtcattgc
     4801 taagtaaatg gaaaacataa gtcaagatgg ctactatata catcgccata aatcctggaa
     4861 tgatagaagt gaacggctta gcaatcgcag ggggaactga atctggtaac ttgattaccc
     4921 agttcttttt cattacttta cagaaaataa tagaggctaa aaatccaatc atcatggctg
     4981 taaagtagcc tctggcatta atatggtttc ctggaatcac attcccaata gttaccatca
     5041 gatttttacc atcaaatgct agattatcaa ttccttgtaa gatttgatct aatttcacat
     5101 ctcctacatt tgccaaaggg aaactctttg taactgtact tccaatcgaa atgacaaacg
     5161 aagcaagcga taccaaacca gcagaaactg tatcaacctt ataaatctta gcgatattca
     5221 ctcccaagca atagatgaac aataaggaaa caattggtat acttcccttg aataccaaat
     5281 tattgatgtc aacaagccac tgaaaggttt tcgtaatact ttctaggtga aattgttgtg
     5341 gtaaatccac tagaaaagca tttaataaca aagcaatgga acctgtcata ataacaggca
     5401 tagtccccac aaatgaatca cgtaaagcaa ctaaaaactt ctgattccca actttcattg
     5461 caattggaga aagtttttct tgcattttat ccaacattgt attcatagca aattcctaat
     5521 ttttttcaaa tcgttcgtat acttctacca cttctttcgc caagtcaaca aaggtcagac
     5581 tcgtcattaa atgatcttgc gcgtgtacca tcaagaggct aattgatgtt tcttccccct
     5641 gtgcctcttt tgtcaacatt tctgtttgag ccttatgcgc ctgtaataag gcagcattcg
     5701 catcagctaa tcttcgattg gctttagaga aatccccttt ttttgctgcc tgaatagcct
     5761 ccatagcatt acttttggct tccccaccat acataattag ccccattgca gattctaaat
     5821 tactttcatt catagcattc tcctcaatct tagtctaata aactttcagc taaatctaag
     5881 actttagaac cattcatcat tccataatct gtcatcggaa taaccgccac aggaatctgt
     5941 ctatctttta gtttttcttg aaagtcccct agtaaatagc gaacttgagg gcctaaaagc
     6001 aacacattta cttcttttgt tgctacaatt tcttctgctt caggagctgg aactgcaaaa
     6061 atttctgcat ccaacccctt atcttctgct gccttttgca tctttgtcac tagcagactt
     6121 gtactcatac ctgctgcaca tgctaacata attgttactt tagccatagc ttactccttt
     6181 atcacctatt tactgaccta gccaagcgag atactgtatg tctcactcct ctaattgcct
     6241 tgctcaatgc ataaatatta tcgactgttg ccagtccccc atatcctgcg tcacctatat
     6301 gttgaatatc aactccacaa attttatttc taagtgcaat ttccttaata gtatctgtat
     6361 cagatgtttc ttggctagta ccaatagcac tcaatacaag accaccctta ctatgaacga
     6421 gatcaacgac ttcacgcaac tcttggtcat gaaaggctgg aacggttcca actgctggaa
     6481 caagtatcac atccgcacct gcttccaaca attgctctgc gacagaaagc tctgccacag
     6541 gctcattcac tcctgccccg tgcatcttac ctgcaataat caaaccagaa aagttttcct
     6601 tagcagtttg aacagcctta atgatttctc gattgctaac tcctgttcca ggatttccag
     6661 tcaaacagac aaagtcaaaa cctaactcct ctattcgctt caatgtttca acactagcaa
     6721 cacgacctgc aacaatttcc tgtgtttcct ctagcatctt tgcagatggg tcaatcggtt
     6781 ccaaatttac accaattgga caagcaacaa gctggtgtaa gcgatgaata acatcatcac
     6841 ctgaactatc caaagcataa attttaggct caaaaacatc aacacaattc aataaaatca
     6901 tatcagctcc aaaagctcta gcaatttcag aattagttat atccccaaca aatgtctcac
     6961 gagtaactac attttcagat agaacaactc taccttcact tgctaaaata ctttgtttta
     7021 attcttcagc attcatctgt aatatctcag atggatttgc actaattaaa cgtttcattc
     7081 gcaatcctcc aataacttaa accgtttttc aatagctatt acaaatggta aataaagtaa
     7141 gacatccaaa acaatcaata caatttgtaa taatgaacca gaaatacttc ctgtagcaag
     7201 taaaccactt ataacaggtg gcatagtcca acctggatct gtataagtta gcggaaccaa
     7261 acctgatgcc attgctcccc acgctactag taagttaaac attggagcta agataaatgg
     7321 aactagtaac aaaatgttca aaacaatagg aacgccaaac attgctggtt catttatatt
     7381 aaataatcca ggtataacag ttataggtgc caaagttttt agttgtttac tagctttctt
     7441 cttatgtgct aaatatccta acgcaagaac taaacctatg gttgcaccac cgccacctat
     7501 gaatacaaaa ttatccataa atacgctagt aaaaatattt ggaagagttt ctccagtttg
     7561 ataagctact ttatttgcat ctagattagc taaccataac ggtttcataa ctgcattaac
     7621 aacatttcct ccgtgtaatc ctacaaacca aaaactacta ttaaggaaaa ttaagataag
     7681 aaggccaata acattatttc ctaaaagtcc aagtggacct cccaaagcta cttgagcaat
     7741 ttcatgaaga ttaggtaaac ttaatttatc taaagttgca taaacaatca accaaccaac
     7801 aatagtcact gcaccaggaa taatggcact aaagctttta gatactgctg gtggaacacc
     7861 atccggcatt tttatctgta tattatgatt tataaaccat tggtagatat agccattaat
     7921 caatcctaaa atcatagcaa caaataaacc ttttgatgcc atgaaagcgg taggcattcc
     7981 tgctccagcc tctcctctaa tgaaaggcgt aactgtaata aaagatgata atgacacaat
     8041 accagcagga ataccatcaa ctttgtattg tctagccata aagtaagcga taccaaaact
     8101 agctacaaga ccaagtaatc caaaactact atcaacaccc ttccataaat agtcagcaac
     8161 accaatatca cccagatatt tttcccatcc tggaatagga aaacttgcaa taaccattag
     8221 taatgaacct atcaacaata aaggtatagt tagagtaata ccgtctcgaa tagaaaccaa
     8281 cgctttatta ttacccaatc tagccgctac tggaagtaac ttttcttgta ataatttttc
     8341 cataaccttt tcctcttaaa tatattttat tatcaaaagt tatcaattat ctttattttt
     8401 tgacgtcaag ttgttatttg attatctttt gttatttata ttttacaact ataagaaagc
     8461 cttgtcaagg atttgtgtaa acatttgatt attttttatt atcaatatat aataaaaaga
     8521 gaccagtaag taatgaaaag cttaaaaaga ttaacatcta catttatcca tagcaaaaaa
     8581 tcataggatt ttaagaatct gacaactagg aagaaaacta atatgacctt atctaagaaa
     8641 caattacaac taagagctaa aatactggaa acagtttaca cattaggtcc catttcacga
     8701 attgaaatcg ctactaaaac aggaataaca cctgcaacaa ctagcagtat cacaaatgat
     8761 ctgattaaag aaaatattct cttagaactt ggtgaagacg aacacgatac aagcgtaggg
     8821 agaaaaaaaa tcctgctaga cattcaagct aaacgatttt actacattgg ttgtgaacta
     8881 tctgaaaaac atttcacttt tgctttagga gataatctag gaaatatctt aaaggaagag
     8941 aaagaaattg ttactaaaca gttaatccaa gaaaagggaa atcaactcat taaccagaca
     9001 ctaaagcaat tcttaaataa ctgctctgat tatgaaatag aagcaattgg aatcgcgcta
     9061 cctggtcgct atttagataa ttataaaata acaacaaaca atcctttatg gcaacatatc
     9121 gacttagaaa tgattcaatc ccactttgat aagcctttgt ttttctctaa caatgttaac
     9181 tgtatggcta taggtaaacg cctatttagt cgccaacaga atgaccctaa ttttgcttat
     9241 tttcattttg ctagaggtat gcactgttct tatatctacg acggaaacat ttatgggaaa
     9301 ggaaatctaa tgattggaga aatagggcat acagttgttt catctgaggg agaagaatgt
     9361 agctgcgggc gcaagggatg cttacaaact tttgctggag aatcttggtt aatcaaaaaa
     9421 tcaaaaattc tatatcatca atctccctat tctctacttc ctagtttagt caaaaatgcc
     9481 gatgatattg atatccaagt tattttaacc gcttatcaat taggtgacac tggaataatc
     9541 acacttatcc atcaagcctt actctatctt agtcaaacca ttttaaatat cagtatgatg
     9601 attgactctc aaaaaatcta cctacatagt cctttactaa caaatcaaca catcatccaa
     9661 aaactatata gtgaaatgaa ctacaaaccc aaactgctct ataatcgcct acctgaagtc
     9721 attattgaac cttacaatga ttttacagcc gcacactcag ctattgcact ttgtttgtat
     9781 catacaattc tacattctta attttctatt acatttaata aataggctaa aaagagggag
     9841 tatatcataa aaagcgaata aacctgtttt ctgaaaatca gaattctgtt ttgttcgctt
     9901 tctttatatt tggaattata ctcctatctc ccctttttca taatgtata
//
LOCUS       DBEROT010000055         9858 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.55, whole genome shotgun sequence.
ACCESSION   DBEROT010000055 DBEROT010000000
VERSION     DBEROT010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.55"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            50..547
                     /locus_tag="ACL8CG_001919"
                     /pseudo
     CDS             50..547
                     /locus_tag="ACL8CG_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            704..1129
                     /gene="lacA"
                     /locus_tag="ACL8CG_001920"
     CDS             704..1129
                     /gene="lacA"
                     /locus_tag="ACL8CG_001920"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGS1344463.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1160..1675
                     /gene="lacB"
                     /locus_tag="ACL8CG_001921"
     CDS             1160..1675
                     /gene="lacB"
                     /locus_tag="ACL8CG_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGS1344464.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1686..2615
                     /locus_tag="ACL8CG_001922"
     CDS             1686..2615
                     /locus_tag="ACL8CG_001922"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGS1344465.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            2617..3597
                     /gene="lacD"
                     /locus_tag="ACL8CG_001923"
     CDS             2617..3597
                     /gene="lacD"
                     /locus_tag="ACL8CG_001923"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGS1344466.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3831..4667
                     /locus_tag="ACL8CG_001924"
     CDS             3831..4667
                     /locus_tag="ACL8CG_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGS1344467.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLITENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4703..5020
                     /locus_tag="ACL8CG_001925"
     CDS             4703..5020
                     /locus_tag="ACL8CG_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1344468.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5022..6716
                     /locus_tag="ACL8CG_001926"
     CDS             5022..6716
                     /locus_tag="ACL8CG_001926"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS1344469.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6931..8337
                     /gene="lacG"
                     /locus_tag="ACL8CG_001927"
     CDS             6931..8337
                     /gene="lacG"
                     /locus_tag="ACL8CG_001927"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS1344470.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDVIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8380..8637
                     /locus_tag="ACL8CG_001928"
     CDS             8380..8637
                     /locus_tag="ACL8CG_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGS1344471.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(8915..9676)
                     /locus_tag="ACL8CG_001929"
     CDS             complement(8915..9676)
                     /locus_tag="ACL8CG_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1344472.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         3148 a         1669 c         1992 g         3049 t
ORIGIN      
        1 tgctggcatt atcaatcatg aactaggatt ctagttttgc aggaagtcta ataaagaaac
       61 tagcaaggtc aggccttact ttattggtgg acatccagga tttaattgtc ctctacttga
      121 tgatgaagtc tatgaagatt attatctaga gtttgagaaa gaagagactt gctctgttcc
      181 acgtcctttc ccagaaacag gtatgttgga tttccaagat agaagtccat ggctagaggg
      241 acaaaaagaa atagatctta gttatgatct tttcagcaaa gatgcagtga ctttggatga
      301 attgcaatct cgaacaattg cccttcgttc tcttaaacat gataggggat tgaaagtgca
      361 ttttgcagaa tttccaaacc tcatcatctg gtcaactttg aacaagggac ctttcattac
      421 ctttgaacca tggtctggct tgtcaacatt ccttgaagaa ggagatcatt tagaagataa
      481 gaagaatgtt tgtctcttag aagccaatca ggttgaagaa ttagggtttg agatagaagt
      541 tttataaaaa agtaaaaaat aaataacaaa aacaaacaca aactgttgac ttcttcaaac
      601 aatagtagta tattatgttt gtgaggacta attgactgtt ttttaaagac agccaataca
      661 ctgctggaat ccagcataga aaaaataaaa aggagtatac aatatgtcta ttgttatcgg
      721 tgcagatgct gcaggtttga gattgaaaga agttgtgaaa gacttcttag aaaaagaaaa
      781 cttccacctt gtggatgtta cagctgaagg tcaagacttt gttgatgtga ctctcgctgt
      841 tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc gtgattgatg cttatggagc
      901 tggtccattt atggttgcaa ctaagatcaa aggaatggtt gctgcagaag tttctgatga
      961 acgttcagct tatatgactc gtggccacaa caactcacgt atgatcacta tgggggcaca
     1021 acttgttggt gatgaattgg ctaaaaacat cgctaaagga tttgttaatg gtaaatacga
     1081 cggtggtcgt caccaaatcc gggttgacat gttgaacaaa atgggctaat tagattatag
     1141 taagaaaggt aagttaaaaa tgagaattgc aattggatgt gaccacatcg taacagatga
     1201 aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat gaagtcattg actttggtac
     1261 atatgaccat acacggactc actacccaat ctttggtaaa aaagtagggg aagctgtaac
     1321 tagcggtcaa gctgatcttg gagtatgtat ctgtggtact ggtgttggta tcaacaacgc
     1381 tgtaaataaa gttccaggtg ttcgttctgc cttggttcgt gatatgacaa cagcccttta
     1441 tgctaaagaa caattgaacg ctaacgttat tggttttggt ggtaaaatta ctggtgaatt
     1501 gcttatgtgt gatatcatcg aagctttcat ccatgctgaa tacaaaccaa ctgaagaaaa
     1561 caaaaaattg attgcgaaaa ttgaacatgt tgaaagtcac aatgctcaac aaacagacgc
     1621 aaacttcttt acagaattcc ttgagaaatg ggatcgtgga gaataccacg actaagaggt
     1681 gacctatgat tttaacagtc acaatgaacc catccatcga tatttcctat cccttggatg
     1741 agttgaagat tgatactgtc aatcgtgtgg tggatgtaac caaaacggct ggtggtaagg
     1801 gactcaatgt tacccgagta ctttcagaat ttggcgattc tgttcttgct actggtttag
     1861 tgggtggcaa acttggtgag tttttggttg aacatatcga taatcaagta aagaaagatt
     1921 tcttctcaat taagggagaa actcgtaact gtatcgctat tctccacgga gacaaccaaa
     1981 cagaagttct tgaaaaaggt cctgaagtat tggaacagga aggtcaagag tttttggaac
     2041 atttcaaaaa actcttggag tcagttgaag tagtggccat ctcaggtagt ctgccagctg
     2101 gccttccagt tgattactat gcgagcttgg tagaacttgc taatcaagct ggcaagcctg
     2161 tagtcttgga ctgctcaggt gcagcacttc aggctgttct tgaatcaccc cataaaccaa
     2221 cagtcatcaa accaaataat gaagaattgt ctcagcttct tggaagagaa gtttctgagg
     2281 atttggatga attaaaagaa gtacttcaag aacctttgtt tgcagggatt gaatggatta
     2341 tcgtttcact tggtgccaac ggtacttttg ccaaacatgg tgacactttc tacaaggtag
     2401 atattcctag aattcaggtg gtaaatcctg ttggatctgg agactctact gtggcaggaa
     2461 tttcttcagg acttcttcac aaagaatcgg atgcagaatt actcatcaag gcaaatgtcc
     2521 ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt caacatggcc aactatcaag
     2581 ttctatatga tcaattaata gtaaaagagg tataaaatgg ctttaacaga acaaaaacgt
     2641 gtacgcttag aaaaactttc tgatgaaaat ggtatcatct cagctcttgc atttgaccaa
     2701 cgtggtgctt tgaaacgcct catggctcaa caccaaacag aagaaccaac tgtggcccaa
     2761 atggaagaac ttaaagtctt ggtagcagat gaattgacta aatacgcttc atctatgctt
     2821 cttgaccctg agtatggact tccagcaact aaagctcttg atgaaaaagc tggccttctc
     2881 cttgcttatg aaaaaacagg ttatgacaca acaagcacaa aacgcttgcc agactgcttg
     2941 gatgtctggt ctgcaaaacg tattaaagaa gaaggtgcag atgcagttaa attcttgctt
     3001 tactatgatg tagatagctc agacgaactc aatcaagaaa aacaagccta catcgaacgc
     3061 atcggttctg agtgtgtggc tgaagatatc ccattcttcc ttgaaattct tgcttacgat
     3121 gaaaaaattg cggatgcagg ttctgtagaa tacgcgaaag taaaaccaca caaagttatc
     3181 ggcgctatga aagtcttttc agacccacgc tttaacattg atgtcttgaa agttgaagtt
     3241 cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg aagtagttta tacacgtgaa
     3301 gaagcagcag ccttcttcaa agcgcaagat gaagcaacga acttgccata catctacttg
     3361 agtgctggtg tatcagctaa actcttccaa gatactcttg tatttgctca tgaatcaggt
     3421 gcaaacttta acggagttct ttgtggccgt gctacatggg caggatcagt tgaagcttac
     3481 atcaaagatg gtgaagcagc agctcgcgaa tggcttcgca caactggatt tgaaaacatt
     3541 gatgagctca ataaagttct tcaaacaaca gcgacttcat ggaaagaacg tgtgtaagaa
     3601 agtcctccta gtttaggaac atgaatctaa aaaaatttaa aaaaagttgt atgtaaaggt
     3661 ttacaaaata acttacttgt gctatactta aatcacaagt taatacaagg tgagtgttac
     3721 taagtaatat taggcatgat cacaggtgaa ttagaaatca gctgattttc tagttcattt
     3781 gtggtcattt tttgtactca tataccttta agatataaaa ggaggttgac atgtatcgaa
     3841 ttctaaatcc aatgaatcac aatgtctcgc ttgtcagaaa tgataaggga gaagaggtga
     3901 ttgtaattgg taaggggatt gcattcggaa agaagaaggg ggatttgatt actgaaaatc
     3961 aggttgagaa aatctttcgg atgaagaccg aagagtccag agaaaacttt atggctcttc
     4021 tcaaagatgt tccgcttgat tttatcacag tgacctatga aatcattgat aagctatcaa
     4081 agaaatatca ttatccgatt caagagtatc tctatgtaac cttgacagat catatttact
     4141 gttcttatca agctctaact caaggaaggt acaaggatag taatctgcca gatatttccg
     4201 ctaagtatcc tgtcgctttt caaatcgcaa atgaagcttt tgaaatttac cgtcagaagc
     4261 tagcagatca ttttcctgag gacgaaatta ttcggattgc ttatcatttc attaatgctg
     4321 aaggtgaaaa tgaagtggaa cttgtggagt cgattgataa gaggaaagaa attctcagga
     4381 atgttgaaga agttttaacg gactatgcaa ttcaacgaac taaaaagaat aaccatttct
     4441 atgatcgctt tatgatccat ttgaattatt tcttggatta tttagacaga tctagagatg
     4501 ataaccaatc acttctggat atggaagatc atattaaaca atcctatcca aaagccttcg
     4561 agattggttc caagatctat gatgtgatta cgcaacatac gggtcttgat ttgtataaaa
     4621 gtgaacgagt ttatctagtt ctacatatcc aacgtttatt gtcataaaaa tttatttaaa
     4681 actatataag gagaattcta tcatgaatag agaagaagta acattgttag gttttgaaat
     4741 cgtagcctat gctggcgatg ctcgttcaaa actattggaa gccttgaagg ctgctgaagc
     4801 tggtgatttt gaaaaagcgg acgctctggt agaggaagct ggtagctgta ttgcagaggc
     4861 tcaccacgcg caaacaagtc tattgactaa ggaagcttct ggtgaggact tagcgtatag
     4921 tgtgaccatg atgcatggtc aagatcactt gatgacaact atcttgttaa aagacctaat
     4981 gcaccattta attgaacttt acaagagagg agttaaataa aatggataag ttaataattt
     5041 ttattgagaa aggaaagcct ttctttgaaa aattatcgag aaatatatac ttaagagcga
     5101 taaaagatgg ttttatttcc agtatgccag cagtattatt ctcaagtatt tttatactaa
     5161 tagctgctgt gcccaatatt tttgggttta aatggtctga tgaacagtta gcttttattt
     5221 tgaaacctta caactactca atgggaattt tagctctctt agtagctggg acaactgcaa
     5281 aatcgttaac agattcagtt aatacacgta gtatggagaa aaccaaccaa atcaactaca
     5341 tgtcaacttt tttagcagct gttgttggat tgttaatact ggcagctgat ccaattgaag
     5401 gtggatttgc taatggtctt ttaggtacta gaggattact tactgcattt ttggcagctt
     5461 ttattacagt aaatatctat aaagtatgta ttaaaaataa tgtaaccatt agacttcctg
     5521 aagaggttcc accaaatatt gcacaagttt ttaaagatgt tattccgttt gccttatctg
     5581 ttctttcaat atatggattg gatttaattg ttagaaatat ttttggtaca aatgtagcag
     5641 aatctgttgg taaaatatta gcccctctat tttcagctac tgatggttat atcggtttag
     5701 ctattgtatt tggtgcttat gctttctttt ggtttgttgg aattcatggg ccatctgttg
     5761 tagaaccttt aattgtagct atcagttatg caaatataga agctaatgtt cagcttgtgc
     5821 aagctggtat gcacgcagat aaaattttaa atccagttac tcaaactttt gttgtaacaa
     5881 tgggtggtac tggtgcaaca ctagtagttc catttatgtt tatgtggtta tgtaaatcaa
     5941 aaagaaatag aattgtcgga cgtgcgtctg tagttcctac tttctttggc gtaaatgaac
     6001 caatcctatt tggtgctcca attgttttaa atcctatctt ctttattccg tttgttactg
     6061 ctcctattat caatgtttgg attatgaaat tttttgtaga tgttctacaa atgaatagtt
     6121 tcagtattat tttaccttgg acaacacctg ctccaattgg tattgttatg ggaacggcgc
     6181 tggctccatt gtcattcgtc ttggctataa ctttaatcat tatcgacact ttaatctatt
     6241 atccatttgt taaagtttat gaccatcaaa ttttagaaga agaacggaaa ggaaactctt
     6301 catctgaatt gaaagaaaaa gttgctgcaa acttcaacac tgcaaaagcg gatgctattc
     6361 ttgaaaaagc gggtgtcgat gcagcacaaa ataccatcac tgaagaaaca aatgtcctcg
     6421 ttctctgtgc tggtggaggt acaagtggac tccttgcaaa tgctttgaat aaggcagcag
     6481 cagaatacaa tgtccctgtg aaagcagcag caggcggcta tggtgctcac cgtgaaatgt
     6541 taccagagtt taatctagtt atccttgccc ctcaagttgc ttcaaacttt gaagatatga
     6601 aggcagaaac agataagctc ggtattaaac ttgctaagac agaaggcgct caatacatca
     6661 aattaactcg tgatggaaaa ggtgccctag cattcgtaca agagcaattc gattaaggct
     6721 aggaactgtg aaacagtctc ccatcgttac ggaaatcgct atggcgaatt tcctaatcgc
     6781 cttattaatt cgtcggtaaa aagatatcgt ttttacctcc tcatgtcaca attcagtgac
     6841 ttggtacaag aagtgagatg gagaagcatg gctcactgac tcctctcctc tcacttttac
     6901 tttatttaaa tcaagaaata ggtgaaaaaa atgacaaaaa cacttccaaa agactttatt
     6961 ttcggtggcg caacagctgc ttatcaagca gaaggtgcta cacatactga tggaaaagga
     7021 ccagttgctt gggataaata tcttgaggat aactactggt acactgccga accagctagt
     7081 gatttttaca atcgatatcc agttgacctc aagctagcag aagagtatgg tgtcaatggt
     7141 attcgaattt ctattgcttg gtcacgtatt ttcccgactg gttacggcca agtaaatgct
     7201 aaaggtgttg agttttatca taatttattt gcagagtgtc acaaacgtca tgttgagcct
     7261 tttgtaactc ttcatcactt tgacacgcca gaagctctcc actcaaatgg agacttctta
     7321 aaccgtgaaa atatcgaaca ttttgtagac tacgctgctt tctgttttga agaatttcca
     7381 gaagtaaact attggacaac ctttaatgaa attggaccaa tcggtgatgg tcaatatttg
     7441 gttgggaaat tccctccagg tatccagtac gaccttgcca aagtctttca atcacaccac
     7501 aatatgatgg tgtctcatgc acgcgcggta aaattgtaca aagagaaagg ctataaaggg
     7561 gaaattggtg ttgttcacgc cctgcctact aaatatcctc tagatcatga aaatccagca
     7621 gatgttcgtg cagctgagtt ggaagatatt attcacaaca aatttatttt ggatgcaacc
     7681 tatctgggtc actactctga aaagactctg gcaggggtag aggctatctt ggctgccaat
     7741 ggtggtagct tggatcttcg tgaagaagat tttacagcat tagaagctgc aaaagacttg
     7801 aatgatttcc taggaatcaa ctactatatg agtgactgga tggaagcctt tgatggagaa
     7861 actgaaatta tccataatgg taaaggtgaa aaaggaagct ctaagtatca aatcaaaggt
     7921 gttggtcgtc gtgtagctcc tgactatgta ccacgcacgg attgggattg gattatctac
     7981 cctcaaggtt tgtatgacca aatcatgcgc gtgaagaaag attatcctaa ctacaagaag
     8041 atttacatca ctgaaaatgg tctcggctat aaagatgagt tcgttgataa cactgtttac
     8101 gatgatggtc gtattgatta cgtgaaacaa cacttggaga tcttgtctga tgtgattgca
     8161 gatggagcta atgtaaaagg ttacttcatt tggtcattaa tggatgtctt ctcatggtca
     8221 aacggttatg agaaacgtta tggtctcttc tacgtagatt ttgaaactca agaacgttat
     8281 cctaagaaat cagctcactg gtacaagaaa gtagcggaaa ctcagattat agactagtag
     8341 aattagtcat tagatataga attttagtga gtcaaaaaga tgttcaaaga ttttatccaa
     8401 tctatttatg aaaaagttta tattataaat ttcgaaaaat gctctcaaat accgtgtttg
     8461 acgagtgaag aattgaaaag tcttggaaaa tggtatgtct cgactggtaa agaatggatt
     8521 tgtcattcag atgatgagct ggaagaattt aaaaatctat ttttaaattt tatcaatcct
     8581 gaagaatggg atactatctc ctttgattca gattttatgc cgtttcaaca atcgtaacca
     8641 atttctcaaa aaagttaaat cttatattta gtactctgta aaactcttat ctaatcacgt
     8701 tgcttatact caatgaaaat caaagagcaa ctttaaacta ggaagcgagt cgcagatttc
     8761 tcaatgcata gctttgagga attgggcaaa aagtctttga tatagaaaaa cgcatagtat
     8821 caggtgtttc aacacctgat actatgcgtt ttattgtggg aagatttact tttttcttct
     8881 gaaattgagt tgttacccag gctctttcag tttattaagg cttgatgact ttaatgtgtt
     8941 tagatagctt aaaaaggatt gaatcactta gtttagaatc tgaaacaata gtatcaagat
     9001 ttgatacatt ataaaaagta taaaaatcaa acttattgaa cttgctatga tctgcgagta
     9061 aatatttttt attagaatta tttaaagcga tgcgttgagc ctctccctct tcctcgctaa
     9121 aagtagctag agctccgttt tgaataccat tacagctaac gaaagcttta gaaaattgga
     9181 gattagagag attttgtagg gtcaatgtac caacaaaagc acctgtaata tcgcgataat
     9241 ttccacctat taaaatcaaa tctgttaatt ttcgttcgct taaaatcaga aaaacaggta
     9301 gactgttggt tacgacgcgg atattgtcaa taggcaactc acgcgcaaaa aactctaatg
     9361 ttgttcctgg tccaatgaaa atagtttctc tttcttctac tagactgcct gcaaaatggg
     9421 ctatttcttg tttttctgcc gtttggaggg cttgtttttc aatatttgat cgctcattag
     9481 tcaaaaggga gttggttcga agtttttcag ctccaccatg cacacgaatc agcaaatctt
     9541 tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc tgaaacggct atttcgtcca
     9601 taatctgttt aactgttatg gttcctttac tatttactat ctctaaaatt ttggctaatt
     9661 tttcttgttt gagcatatta tcacctcgtt tcctactact atcttaccat aaacaaactc
     9721 atcattcaaa tacaaaaaca acaaaataaa acaaaaacaa aaatatcgag gtttattttc
     9781 aaaactttcg atatttttat taagttatta ttttgttgtt tctagtttac tttttgatgg
     9841 ttaagagtgg tggagaat
//
LOCUS       DBEROT010000056         9585 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.56, whole genome shotgun sequence.
ACCESSION   DBEROT010000056 DBEROT010000000
VERSION     DBEROT010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9585
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.56"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            32..705
                     /locus_tag="ACL8CG_001930"
                     /pseudo
     CDS             32..705
                     /locus_tag="ACL8CG_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
     gene            complement(747..2735)
                     /locus_tag="ACL8CG_001931"
     CDS             complement(747..2735)
                     /locus_tag="ACL8CG_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344473.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVIAVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSDIYNQFYGGMNVSISEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2737..3495)
                     /locus_tag="ACL8CG_001932"
     CDS             complement(2737..3495)
                     /locus_tag="ACL8CG_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344474.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3923..4114
                     /locus_tag="ACL8CG_001933"
     CDS             3923..4114
                     /locus_tag="ACL8CG_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344475.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4468..4740)
                     /locus_tag="ACL8CG_001934"
     CDS             complement(4468..4740)
                     /locus_tag="ACL8CG_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS1344476.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4799..5248)
                     /locus_tag="ACL8CG_001935"
     CDS             complement(4799..5248)
                     /locus_tag="ACL8CG_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGS1344477.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            complement(5235..7364)
                     /locus_tag="ACL8CG_001936"
     CDS             complement(5235..7364)
                     /locus_tag="ACL8CG_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGS1344478.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFVTRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            7417..7575
                     /locus_tag="ACL8CG_001937"
     CDS             7417..7575
                     /locus_tag="ACL8CG_001937"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344479.1"
                     /translation="MKIKKQTRKLAAGCSKYCFEVVDKTDEVSSKHCFEVVDRTDEVS
                     NRTTVRRS"
     gene            7689..7820
                     /locus_tag="ACL8CG_001938"
     CDS             7689..7820
                     /locus_tag="ACL8CG_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGS1344480.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            7821..8726
                     /locus_tag="ACL8CG_001939"
     CDS             7821..8726
                     /locus_tag="ACL8CG_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGS1344481.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            8723..9538
                     /locus_tag="ACL8CG_001940"
     CDS             8723..9538
                     /locus_tag="ACL8CG_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGS1344482.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
BASE COUNT         2816 a         2032 c         1845 g         2892 t
ORIGIN      
        1 ttgaaattta gcgtcagaaa caaatcacga aattgattca aattttgcag gtcgtttaaa
       61 tatcctgcgt gcgggtgttc ttgatgctaa cgatggaatt atttccattg ctggtgtggt
      121 tatcggagtt gccagtgcca cgagcaatat ctggattatc tttttatcag gttttgcggc
      181 tatcttagct ggtgcctttt caatggctgg tggagaatat gtatccgttt caactccaaa
      241 agataccgag gaagctgccg tttcgcgaga aaaactcttg ctagaccaag atagggaact
      301 agccaaaaaa tccctctatg ctgcttatat ccaaaatgga gaatgcaaaa cttctgccca
      361 actcttgacc aataagatct ttcttaaaaa tccactcaag gctctggtag aggaaaaata
      421 tgggattgag tatgaagaat ttaccaatcc ttggcacgct gccatttcta gcttcgttgc
      481 ctttttcctt agaagtttgc ctccaatgct gtcagtgacc atattcccaa gtgaatatcg
      541 catccctgct actgtcctta ttgtcggtgt ggcccttctt ctcactggtt acactagtgc
      601 cagacttgga aaggatccga ctagaacagc tatgattcgg aacctagcta tggtctcttg
      661 actatgggag ttaccttcct gctcgaacaa cttttcagca tttagaatac aagaaatacc
      721 tcgattttga agtcgaggta tcttttttac atttgcacaa tcttacgata acttcttgaa
      781 gtaatcatga aaatcagcac ataggcgatg aggaagatag cgcagataga caaggtcacg
      841 atcaacatca tagtcgtatc cagtacacca atcactttta aaatcaggct aagcatatgg
      901 taggcaaagg ctagatgtat gaaggcaaaa agcaaaggaa ggaagaaaac agttaaaacc
      961 tgtttgttga tggtttgctt gatttgcttt tgatctaaac cgactttctg caagataata
     1021 aagcgttcac ggtcttcata gccttcagaa atttgtttgt agtagatgac cagaacggtt
     1081 ccgaccataa agataatgga taggaaaata ccaataaaga agacaccgcc aaagaggaca
     1141 ctcatttgag cactagcatc tgctagagtg ctaccataca catagttacc ttcagtgttt
     1201 aattgagcat taaacttttg taagtatttt tcatattctt cagcgacctt gagttgctct
     1261 tcttcactga tacttacatt cataccaccg taaaactgat tatagatatc cgaatctggg
     1321 aattgatcca aaaaggcttg taaatcagga acaacaaggt aattgtaatc agtagtcaag
     1381 atattaaact tatttggaac atggttcaca atgaaatctt tattaaattc ttctttgaca
     1441 gaaaattgat gatcatttag agttagagct ttctgtcctt tcagtccgtc atttttggca
     1501 aagagaccga cctcatttcc tgatagagac agtttttgac cagtcatatt ttcataatct
     1561 ttttggtcaa ataccatgaa aactgttttg ggttggacac ggttttgtcc tttttcaaaa
     1621 atagttaact tggttccttc ttgatttgca ataccaaagt tactgtaacg aagtacttct
     1681 ttctctttga cactataacc tttgtcactt gcaaactggc tcaagagttt gtccaaatct
     1741 tctttttcaa cattttgccc tgaaacccca aaatcatgag gatttagaac ttttttaaag
     1801 ctttctgcgg aattgaaaat gcttgtcgct gctgacatgg ttaccaaaac cattgttgac
     1861 aaaatagcga tggttgctag tccaaccgca tttttcttca tacggaaaat caagttggaa
     1921 acagatatga ggttattagg ttggtaatag tatttcttgt ttttctttaa gatttgtagg
     1981 aagactgtaa tccctgcatt aaacaagaga taggtcccaa agataaccag taaaacagct
     2041 atgaagaagg ttgttaaggc tgtaagagga tcttttaccg taagggcaag ataatagcca
     2101 atccctaaac ttatggaacc aagaatagtt tggagaggta ggaaacgacc tcttttctct
     2161 ccgcttgctt tctcacgcga gagctggagg gcattcatac gggcgattcg aagggcattc
     2221 aggaacatga ggcctaggaa aatcaatcca aagacaagaa gtactgcaat gacaactttc
     2281 atctggaagg tagcaaccag ctcaaccttc aatttcatta gtttgagcag gaaagcgaaa
     2341 attaacttgt caaacaaggc tccaataccg atacccgctc caacagttag aatcccaaat
     2401 accactaact ccttaaaggt catactgata agatgacgct tctccaagcc caacatgcca
     2461 taaattccta gttccttgga acggttcttc atgacaaaac tattggcata gagaacgata
     2521 atggctgacg caagggtgac gacaaacata ccaaatccaa gtgtagcctg aatggttgtt
     2581 cctccacgaa tttcagcaat cttgggattg aaggttagag agtaaaagag ataggtgaca
     2641 gtgactgcca agagaacagc tagcgcaaaa ggatagtaga gtttgcggtt tttaatcaag
     2701 ttcgataccg ctaacttatt agttaatcga aacatactaa ttcacctcgc ttgccatgac
     2761 agtcaaggta tcagagattt cttggaacat ctgacgttct gtcttctctc cacggtagat
     2821 ttggttgtaa agaatgccgt ctttgataaa gagaacacgc ttggccctgc tagcagctgc
     2881 tgttgagtgg gttaccatga ggatggtttg gccgcgctca ttgatttcat caaagacatc
     2941 aagtaaggct gcagatgact tggagtcaag agctcctgtc ggttcgtccg caaggagaat
     3001 ttcaggttca gtgatgatgg cgcgtgctac tgctacacgc tgtttctggc caccagaaat
     3061 ctcgtaaggg tacttctctt gtaattggtt tattcccaga ttctcagctg tcaccaccaa
     3121 tttcttcatc atctctgtaa taggtcttct tgacaagaca agcggaagca agatattgtc
     3181 ctttacagat agagtatcta gcaagttaaa gtcttggaag acaaagccca acttttcacg
     3241 acggaagcta gaggcctgtg aatttttaat ggttgcggtg tcagttccat tcaagtaaac
     3301 ctgaccacga cttggtttat ccagcatagc tagaatattg agaagagttg atttaccaga
     3361 accagactca cccatgatgg caacgtagtc acccttttcg acggtaaagt gaatatcctt
     3421 gagggcctct acttggttgc cctgaaaacg agttttataa attttttgaa cgtgttttac
     3481 atctaaaagt gtcatgagaa tctcctttct taatatccca tcaaatgaaa tgtcgcttgc
     3541 atcatagcgc atcccagctg aacgcgctcg atttctttgt gacttggttt tcttgttttc
     3601 ttatgtaaga tttgtttcat gatgttactc ctttgttctt tatgagtcta gtttacatca
     3661 aaaaaagacc tcttgccata acctaacctt acaaaagaga ctttaatctt acatttttgt
     3721 aagattgggg gaaatgtaag caaaattact tagaaaatga tttgatttcc tatttttaaa
     3781 attgtaaaat ataaatatga aaaggcttac tttggaaagg aggaagcggg aactaacatt
     3841 ttagtaagct tacctagata acataccatt caatttaaca cttgcaagtc gttcaaccta
     3901 taaggaaaga aggtgcgcct taatgaaaca caaagaacat atactcatcg gacttctcta
     3961 tctgctctct ccattcatcg gtcagctctt agttgaacac acacacttta tcagtacaga
     4021 atttaccggc actgcttatg ttatttgctg gttatcagtt gttatcagca tccaccattt
     4081 ttccaaaaat gtattgtctc aacagcaaaa atagattaaa aaactgcgtt taaattactg
     4141 cttttatagt aaaatgaaat aagaacagga caaatcgatc aggacagtca aatcgatttc
     4201 taacaatttt ttagaagtat aggtgtccta ttctagttcc aatccactat agtttgtgga
     4261 tgaagctggc gaaatattat taatactatt caaaaatcaa agtgcaaact atatcaactt
     4321 cacattgccg actaaattac agcctgcggc tggcttccta gtttgcactt tgatttttat
     4381 tgagtataaa agtaaaaaag ctttaaatca agcagtttag actattgatt taaagctttt
     4441 tgcgtattcc aaatcttttg taaaacctca ccaaaaccag ccttcattat cgtcaatggc
     4501 ttgagcttct ttgcgtttac gtgggcctgt tccgtacatt tctgcttcga tttcttcctt
     4561 ggttggcatg atagaagcta ggatgatata gataatcacc ccaagtccaa agtttgcgac
     4621 tgtaaaaatg gcaaacagaa aacgtacaag ggtaacatca aagttccact tgtctgacag
     4681 acctgctaaa actcctgaaa tcatgcgatt tcgtctcatt ttataaaact tactgttcat
     4741 gatatttcct ctttctgcta ggttagacat agtatatcac ggataggctc ggctttcatc
     4801 agtcctcagg ctgatttact aatagcaact ttcctcgaca aagtccacag cgatagcgtt
     4861 tggtatcaat cctacgctta cgctgataag tttgctggca ggattggcaa cgatagagct
     4921 tgattggctt ggagttacta ttgggcaagg atggtacaaa ccgtaatcca tccactgctt
     4981 tcaacagttc cttaaaatcc cgatccttgt gttgatagcc tttcccttga aaatagaggt
     5041 gataatgaca gagttcatgt cggacaattt tcctaaaaac gtccaacccc agttcctgat
     5101 aaaccttggg attaaaatcc aaatgcccat ctttggggaa aaatcgccca cctgtcgaac
     5161 gtagacgcct attccactgg acatgatgga taaaaggtct gccgaagtct tctagtgaaa
     5221 cctgcttgac gtaatcagtc agtttcattt ggagctagga gagacagatt aactttttca
     5281 cgttcagtat caattttctt aacccaaacg ctcaccaaat ctccaactgc caccacttga
     5341 ctagggtgtt tgataaactt gcgactcata tgggaaatat ggatgagacc gtcctcatga
     5401 attccgatat caacaaaagc accgaaatca acaacgttac gcaccactcc ttctagcttt
     5461 tgtccaacca ctaagtcctt gatatctagg acatcttgac ggagaactgg agcatcaaag
     5521 gaatcacgga aatctcgacc tggtttgaga agatctgcaa tgatatcttt aagagtttct
     5581 ggaccaaggt ctaactcttg cgccatttcc ttgactgaaa gcgacttgag tttgctttgg
     5641 gcctcttcat tcagatcctt aatgtccaag catttgaaga gttccttaac ggcagcgtaa
     5701 ttttctgggt gaactcctgt attatcaagg atattgctac tttcagggat acggaggaaa
     5761 ccagcagcct gttcaaaagc cttggccccc aaacgaggaa ctttcttgat ttgggagcgt
     5821 gaagtgattt ttccctcttc ctcacggtat ttgacgatat tttcagaaat ggttttattg
     5881 agtccagcta cgtgtgaaag aagagctggg ctagctgtat tgacattgac accaacttgg
     5941 ttaaccactg tatcgacaac aaagtccaga ctctcagata gtttcttctg actgacatcg
     6001 tgttggtatt gaccgacacc aattgactta ggatcgattt tgaccaattc cgcaagagga
     6061 tcttgcaaac gacgggcgat agaaatggca gagcgttttt caacggtcaa gtctggaaac
     6121 tcctgacgag caagttcgct ggcagaatag acagaagcac cactttcatt aacgataaca
     6181 tagctgactt cagggaaatc tttcagaact tccgctacaa aagcttcact ttcacgactg
     6241 gccgttccat ttccaatggc aataatctct acaccgtatt gaccaattaa atctgctaaa
     6301 tctttcttgg cttcttcgat ttgacgagct gatgctggtt taacaggata aataacctga
     6361 gttgtcagca tttttcctgt tgcatccacg acagctagct tggcacctgt acgaaaggct
     6421 gggtcaaacc caagaaccac gcgccctttc agtggagcaa ccaagaggag attgcgcaga
     6481 ttgtcagaaa aaagttggat agctccctct tcagctttct cagttaattc tgtccgaata
     6541 cgacgctcaa tagcaggcaa gacctttttc ttaacggatt gctgaacaac ttcatcaata
     6601 taagcatttt tcaccttgaa acgagtaaca aagaaggcaa gaatacggtc cgtcgcatgt
     6661 tcaaaaccga tcttcaagac accaagtttc tccccacgat tgagagccaa ggtacgatag
     6721 ccttgcatag ttccaactgt ctctgaaaaa tcataataaa tctgaaaaac ctgcttttca
     6781 tcaagacttt catccttggc ttgagaagtg agtttagagt gtctcagcac ttcctgataa
     6841 gtcatagaac gcaaggtcac atcttccgat aaggcttcga ccaaaatatc aactgcaccg
     6901 gtcaaggctt ccttgccagt cgcaaatcct tcacagacga acttttcagc ttctttctct
     6961 aagtcaacta tattctgcaa aatcaagcga gcaagaggaa agagtccagc ttcacgggca
     7021 atggttgcct tggtacgacg cttttcctta taaggaagat agagttcttc aacgtctgct
     7081 aatttttcgg caactaagat agcttcttcc aattccttgg tcaacttgcc ttgctcttga
     7141 atcttagcta agacagcttc cttacggtca ttgagatttg tcagactttt atccaaatca
     7201 ataatagcct taatcgccac ctcatccaga ctaccagtca tgtccttacg ataacgcgcg
     7261 ataaagggaa tagtcgcccc ttcagctgtc aaacttagaa cggtatcaat ttgctttaac
     7321 gtcactccca aatcctgaga gattttttca tattttttat ccataaatct attataccac
     7381 aagctggaag gctttctcca atccttttca tactcaatga aaatcaaaaa gcaaactagg
     7441 aagctagccg caggctgctc aaaatactgt tttgaggttg tggataagac tgacgaagtc
     7501 agctcaaaac actgttttga ggttgtggat agaactgacg aagtcagtaa ccgtactacg
     7561 gtaaggcgaa gctgacgtgg tttgaagaga ttttcgaagt gtatcaacta tcgaaaacaa
     7621 attaaaaaac tcccttttcc gcaaaataat agtataatag aggtagaatt tagaatcgag
     7681 gtacacctat ggctgtcaaa tttacaaaac gagacgactt ggacaagatg tttgaagagt
     7741 ttgctaaact ccctgatttg aaacaagtta ctttccctga tgacaaagag aaaaaagtca
     7801 aagcagaaaa gaaaaactag atgactgctt ttcaacaact cccatctagt gtacttcaaa
     7861 ctggagccat ttttctctcc attatcattg aagcccttcc cttcgttctg ataggaagca
     7921 ttgtctcagg gctgattgaa gtttatatca cacctgacaa ggtttatcat tttctccctc
     7981 gaaatcgttg ggggagaatc ttttttggga cctttgtcgg tatacttttc ccttcttgtg
     8041 aatgtggaat cgtccccatc atcaatcgtt ttctggaaaa aaaggttcca agttacacgg
     8101 ccgttccttt tcttgtgaca gcacctgtta tcaatcccat tgttcttttt gcgacctatt
     8161 ctgcctttgg caactccttc catgtcgccc tattacgagc tctgggttcc attcttgtgg
     8221 ctgtaatact aggaattttt ctaggatttt tctggcaaga accgattcag aaagaaaatc
     8281 gtctagcttg tcatgagcat gatttttctt acttgagttc tgcaaaaaaa gtttttcaag
     8341 tctttgtgca ggccattgat gaattttttg atacggggcg ttatttggta tttggctgcc
     8401 tctttgcttc tataatacag gtctacgttc cgactcggat tctgacctct atcagtgcga
     8461 ctcctctttt tgccatcctg ctcttgatgc ttttggcctt tcttctttcg ctctgtagtg
     8521 aggcggatgc ctttataggt gcttctctac tctcgagttt cggtttggct ccagttctgg
     8581 cctttctcgt cattggccca atgctggata tcaaaaatat tctcatgatg aaaaattact
     8641 tgaaagcacg atttattagt cacttcatta cgattgtgac tctggtcgtt ttagcctatt
     8701 ctctcttgat tggagtcatc ctatgattcg atttttagtt ttagctggct attttgaact
     8761 gactatttac ctccatctgt cgggcaaact aaaccagtac atcaacatgc actattccta
     8821 tctggcctat atttccatgg tgctttcctt tatcttggca attgttcaat tgtatatctg
     8881 gatgaagcaa gtcaaaaccc acagtcatct gaacagccga ttggccaaga tgacgagtat
     8941 ttctcttctg gctattccac ttgtcatcgg cttaactttc ccaactgtta gcttggattc
     9001 tcagactgtt tctgctaaag gttatcattt ccccctatcg gaaggaacgg atctagccat
     9061 tcagacaagc gaagggacga caagccaata tttgaaacca gataccagtt cttatttttc
     9121 aaaatcagcc tatgaaaagg aaatgcgaac ggcggcggat aaatacttat cccaagatag
     9181 tattcagatc actaatgaaa actatatgga agtcatggag gctatctacg actatccaga
     9241 tgagtttgag ggcaagacaa tccagtttac aggctttgtc tataacgacc ccagtcatgc
     9301 caatagtcaa tttctgttcc gattcggcat tatccactgt atcgcagatt ctggtgtcta
     9361 tggattgctg accaagggca atacccggca gtatgaaaac aacacttgga tttcagccaa
     9421 aggaaaactg gtcaatcact accataaaga actcaaacaa aaccttccaa ccttggaaat
     9481 cgacagcttt accaaagtcg ataaaccaga aaatccctat gtatatagag ctttttaaga
     9541 aaatcaaaat aaaaacgaac aagttctctt ctgaataaca gaaaa
//
LOCUS       DBEROT010000057         9555 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.57, whole genome shotgun sequence.
ACCESSION   DBEROT010000057 DBEROT010000000
VERSION     DBEROT010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9555
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.57"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..4116
                     /locus_tag="ACL8CG_001941"
     CDS             <1..4116
                     /locus_tag="ACL8CG_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS1344483.1"
                     /translation="KQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVE
                     APKEYTGKIEQPSAEDTKPENEASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELY
                     TVENNKYRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAH
                     AENLIQHENNVISNDYTYYLPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAR
                     EVELPDDQESYVKNEFYGKLIGENNGKYYAIYNLKKPLFKTLNTATIQNLSIKEANVS
                     SKEDAATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTY
                     DTTVGYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYS
                     YVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAISGDNFDN
                     MKEDHAYSSKGNKVVNVVQVDDELVTKDSDVQRGTVLDADKVKEKKAELVSKHSTKVE
                     DFDFTSRYTTIYNEVTGYQKSREQVYKNIEKLLPFYNRETIVKYGNLVDESSELFTKE
                     LLSVVPMKNNEVITDINKNKQEINKLLLHFEGNKSQVLNIAYKNDFSKVAEYSIEYQG
                     LLYTPNTLLHDYSNIVDNVLTDLNSVQYDSNAIKKILDISDKVKNTELYLDEQFVKTK
                     ANIKDTLSKLLSADAAIAENSNSIIDNYVIQKIKQNKEALLLGLTYLERWYNFKYGET
                     KAKDLVMYHLDFFGKSNSSALDNVIQLGKSGFNNLLAKNNVITYNVLLSKNYGTESLF
                     KALEGYRKVFLPTTSNNEWFKAQTKAYIVEEKSSIPEVSKKQSEQGTKYSIGIYDRLT
                     SPSWKYQSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRSKVHPKGDNLNKFVEDNV
                     REAAKRFRDHYDYWYKILEPENREKLYRSLLVYDAFKFGRDNTEDKVTYQADFETDHP
                     AIKYFFGPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLG
                     GYGRRSGLGPEFYAKGLLQAPDHPYDPTITINSVLKYDDSENSTRLQVADPTQRFNSA
                     EDLHNYMHNMFDLIYTLEILEGRAVAKLDYNAKNDLLRKIENKYKQDPDGNSVYATNV
                     VRRLTMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGT
                     PGDLMGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSKIKSYGKEVGLVTDKLVL
                     EKVFNNRYSSWVEFKKAMYNERIAKFNNLISVSFNNPNVSWGRTNRITITSIANLQNM
                     INTAVNEDAEDFRAQLYPDTNSRVLKLKKAIYKAYLDQTNDFRRSIFENKK"
     gene            4160..>9555
                     /gene="zmpD"
                     /locus_tag="ACL8CG_001942"
     CDS             4160..>9555
                     /gene="zmpD"
                     /locus_tag="ACL8CG_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease D"
                     /protein_id="HGS1344484.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKG
                     EPEVQPVLPEAVVAEKGEPEVQPVLPEAVVTEKGEPEVQPALPEAVVTEKGEPEVHEK
                     PDYTQPIGANLVESEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEPISTVSEV
                     ASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVGEDGERQIVTSYEELHG
                     KKISESVETVTILKEMKPEIIVKGTKERPKEKTAPVLTLTKVTEDAMNRSANLNYELD
                     NKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDLFKDYKIATTMIYDRGQGS
                     ETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMYLKI
                     TSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKPHPK
                     EDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEGKHY
                     TIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVTGNV
                     LGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYVDAN
                     LIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLSHHG
                     YIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKEHHR
                     IKPISQSEADTKIMMLGITAQDFAVNEPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYR
                     NIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYA
                     DGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASVQLI
                     SPEVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADHQLN
                     SDEAAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLL
                     DFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDWFIH
                     AAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYNTMA
                     YSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRVPTP
                     VWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNPNNN
                     DQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSI
                     GHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHVEAD
                     AVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSSIND
                     LIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAF
                     RMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYH
                     DVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVFKAL
                     LKNTDGFFNPLFKK"
BASE COUNT         3555 a         1359 c         1906 g         2735 t
ORIGIN      
        1 aaacaggtag caccgcttcc agaatataca ggaccacaag ccagcgctat tgttgaacca
       61 gagcaagtag caccactacc agaatacaca ggggtacaag ccggatcgat agtcgagcca
      121 gagaaagtag aagcaccgaa agaatatact ggtaaaatcg aacaacctag tgcagaagat
      181 actaaacctg aaaatgaggc aagctctaca aatggggaat cggaacgtcc taaagataaa
      241 attaaagaag aaaaacaagt cgacaagaaa ctagaactta gaaatgtttc aaacgtggaa
      301 ttatatacgg tagaaaataa taaatatcga catattacgg ctgtagatgg tgctttagat
      361 agttcattga agtatttcat gaaggtaaaa tcagaaaatt ttaaagatat aatgttgcct
      421 gttactaaaa ttgaaagtac aacaaaaaac aataaagaag tatacaaaat tgtggctcat
      481 gcagaaaatc taattcaaca cgaaaacaat gttatttcga atgactatac atattattta
      541 ccaaaaactc agcaaagtga aactggcgtc tatacatcat ttaaaaattt agttgatgca
      601 atgaatagtg accctaatgg aacattccat ttaggtgcaa ctatggatgc tcgtgaagtt
      661 gaacttccgg atgatcaaga aagttatgta aaaaatgaat tttacggaaa attaataggt
      721 gaaaataatg gtaagtatta tgctatttat aacttgaaaa aacctttatt taaaactcta
      781 aacaccgcta ctattcagaa tctttcaata aaagaagcga atgtttcttc taaagaagat
      841 gctgctacaa tatcgaaaga agcaaaatac aatactctta tagataatgt tcattctgat
      901 ggtattatag ctggtgaacg tggaattggt ggattggttt caaaagtaga taactcgaga
      961 atttctaata gtagttttac aggcagaata actaacacat atgatacaac tgtagggtat
     1021 gaaattggtg gtttagtagg taaactttct ggttcgcttg cttctataga gaaatcaata
     1081 gcatcgattg acatagcctc taatgcaaaa tcaggagatc aaattgttgg tggtatagcc
     1141 ggagttgttg agaaaagtgc gacaattaag tatagctatg ttgaaggaaa tgttaacaat
     1201 gtgcgacact ttggtaaagt tgggggagtt gcaggtaatc tttgggatag agattcacaa
     1261 gatgtaagta aatcaggtaa actatcatat gttttaagtg atgttaatgt aacaaatggt
     1321 aatgctatat cgggtgataa ttttgataat atgaaagaag atcatgctta tagtagtaaa
     1381 ggcaataaag tagtaaatgt agtccaagta gatgatgaac ttgtgactaa agattcagat
     1441 gtacaaagag gtacggtatt agatgctgat aaagtaaaag agaaaaaggc agaattggtt
     1501 tccaaacaca gcactaaagt agaagatttt gattttactt caagatacac tactatttac
     1561 aatgaagtaa caggttatca aaagtcgaga gaacaagtat ataaaaatat tgaaaaacta
     1621 ttaccgttct ataatcgaga gacaattgtt aaatatggta atttagtaga tgaaagcagc
     1681 gagctattta ctaaagaact tctatcagtt gttcctatga agaataatga agtaataact
     1741 gatattaata aaaataaaca agaaataaac aaattgttat tacattttga aggtaataaa
     1801 tcacaagtat taaatattgc atataagaat gatttctcta aagttgctga gtatagtata
     1861 gagtatcaag gattattata tactcccaat actctattgc atgactacag taatattgta
     1921 gataatgttt taactgactt gaattctgta caatatgatt caaatgcaat taagaaaata
     1981 ttagatatct cagataaagt taaaaatacg gaattatact tagatgagca atttgttaaa
     2041 acaaaagcaa atataaaaga tactttatca aaacttctgt cagcggatgc agcaatcgct
     2101 gagaatagta attcgataat tgataattat gttattcaga aaatcaaaca gaataaagaa
     2161 gctttattgt taggattaac atacttagag cgttggtaca attttaaata tggtgaaacg
     2221 aaagcaaaag atttagttat gtatcacttg gatttcttcg gtaaatctaa tagttctgca
     2281 ttagataatg ttattcaatt aggtaaatct ggatttaaca atttactagc aaaaaataat
     2341 gtaattactt acaatgtatt attatctaaa aattatggaa ctgaaagttt atttaaagca
     2401 ttagaaggat atagaaaagt attcttacca acaacttcta acaatgagtg gtttaaagct
     2461 caaactaaag catatattgt tgaagaaaaa tcttctattc cagaagtaag taaaaaacaa
     2521 tcagaacaag gaactaagta ttctatagga atttatgata gattaactag tccgtcatgg
     2581 aaatatcaaa gtatggtctt accactatta actttacctg aagaaaaaac agtatttatg
     2641 atagcgaata tttcaacaat aggatttggt gcttatgata gatatagaag taaagtccat
     2701 cctaaaggag ataacttaaa taaatttgta gaagacaatg taagagaagc tgcaaaaaga
     2761 tttagagatc attatgatta ttggtataaa atattagagc ctgagaatag agagaaactt
     2821 tatagaagtt tattagtata cgatgcattt aaatttggtc gagataatac tgaagataaa
     2881 gtaacttatc aagctgattt tgaaactgat catccagcta taaaatactt ctttggacct
     2941 gcggggaata atgttgttca taatggacac ggagcatatg ctaccggaga tgcattctat
     3001 tatatggcat atcgtatgtt ggataaagat ggagctgtaa catatactca tgaaatgaca
     3061 cataactctg atagagaaat ttatcttgga ggatatggaa gaagaagcgg attagggcct
     3121 gagttttatg ctaagggctt attacaagca cctgaccacc catatgatcc aacaataaca
     3181 attaactctg tgttgaaata tgatgattca gaaaattcaa caagacttca agtagctgat
     3241 ccaactcaac gatttaatag tgcagaagac ctacataatt atatgcataa tatgtttgat
     3301 ttaatatata ctcttgaaat attagaaggt cgtgctgtag ctaaattaga ttataatgcg
     3361 aaaaatgatt tattaagaaa aattgagaat aaatataagc aagatccaga tggtaattct
     3421 gtttatgcga caaatgttgt tcgcagatta acgatggatg aagttaataa attaaattct
     3481 tttgatagtt taattgaaaa tgatattatt actagcagag ggtacaaaga ccaagaatat
     3541 aagagaaatg gttattatac aattgattta ttttcaccga tttattcagc tcttagtgga
     3601 gagaaaggga ctcctggtga tttaatggga cgtcgtatag cattcgaatt attagctgca
     3661 aaaggatata aagagggcat ggtaccttat atctcaaatc aatatgaaaa agatgcaaaa
     3721 gctgcgggaa gtaagattaa atcttatggt aaagaagtag gtttagttac agataaatta
     3781 gtacttgaaa aggtatttaa taatcgttac tcatcttggg tagaatttaa aaaagcaatg
     3841 tataatgagc gaatagctaa atttaataat ctaataagtg ttagctttaa taatccaaat
     3901 gtaagttggg gaagaactaa tagaataaca ataactagca tagccaacct tcaaaatatg
     3961 ataaatacgg ctgtcaatga agatgctgaa gattttagag cacaattata ccctgataca
     4021 aatagtagag ttcttaaact gaaaaaagca atatataaag cctatcttga ccaaacaaat
     4081 gattttagaa gatcaatttt tgagaataaa aaatagtgtt tactattagg aaataaaaag
     4141 tgaatgtgga ggattagaat tgtcattatt aaaaaaagat aaattttcca ttaggaaaat
     4201 aaagggtatt gttggttcga tattcttggg gagtttttta tttgcactgt cagttgttgg
     4261 tgtatcgact tatcattact tagattatag tactttgaca caaactgaac gtgatcaact
     4321 caaacaaggt agacctgatg aatcaaaaga gtcatatgct ttggtttatg aaaaagacgc
     4381 attaccaaac acaggaagtt ctcaatctat tatgactgta ttgggtttgt tagctatcgg
     4441 gagtcttatt gtgattatca caaaagataa aaagaggaaa aaaatagcta catttttgat
     4501 tgtaggggcg acaggtttag ttacactatc aactgcttca gcacttaatt tgaatgctaa
     4561 catccatgag tctggacgtg atggtgtgtt gcaaatttct ggttacagat atgttggtta
     4621 cttggagctt gatgatagaa ctgtttcgtc ggtttctcca gcatcaactg tttctccagt
     4681 tgagcaaccc aaagttgtga ctgacaaagg cgaaccagaa gttcagccag cgttaccaga
     4741 agcagttgta actggaaaag ggaaaactga agtacaaccg acattaccag aagctgttgt
     4801 gactgaaaaa ggggaaccgg aagtacaacc agtgttacca gaagctgttg tggctgaaaa
     4861 aggggaaccg gaagtacaac cagtgttacc agaagctgtt gtgactgaaa aaggggaacc
     4921 agaagtacaa ccagccttac ccgaagcagt tgtaactgaa aaaggcgaac cagaagttca
     4981 tgagaagcct gactatacgc aaccaatagg tgcaaacctt gttgagtctg aagttcatga
     5041 gaaactagca tacactgaac ctgtaggtac aacaggagta gatgaaaatg gaaacttgat
     5101 tgagccacct gttaacgata ttccagagta tactgaacca atatctacag tttcagaagt
     5161 tgcatcagaa agagaagagt tgccttcttt acataccgat attcgtacag agactattcc
     5221 taaaaccact atagaagaat ctgatcctag caaatttata ggcgataatt ctgttaaaca
     5281 agttggtgag gatggcgaac gtcaaattgt tactagctat gaagagttac atggcaaaaa
     5341 aatcagcgag tcagttgaaa cagtaacaat tttgaaagaa atgaagcctg aaattattgt
     5401 aaaaggtaca aaagaaagac caaaagaaaa aacggctcct gttttaacct tgaccaaagt
     5461 aacagaagat gctatgaatc gttctgccaa cttaaattat gagcttgata ataaagataa
     5521 tgctgaaata tcaagtattg tagctgaaat taaagatggt gatacagtag ttaaaagggt
     5581 tgatttatct aaagaaaaat taactgacgc tgtacaaaat ttggatttgt ttaaagatta
     5641 taagattgca acaacaatga tttatgatcg tggtcaaggt tctgaaacgt ctaaactgga
     5701 tgaaagacct ctgcgtttgg agttgaaaaa ggtcgaaatt aaaaatatcg catctactaa
     5761 tttagtgaag gtaaatgatg atggtactga aacacctagt gattttatga atgaaaaacc
     5821 ttcagaagaa gatgttaaaa aaatgtactt aaaaatcact agtcgcgata ataaggtaac
     5881 tcgtttaact gtagactcta ttgaagaagt gactgaagaa ggtcaaaaac tttacaaaat
     5941 aactgctgaa gcacaagatt tgattcaaca cacagaccca acgaaggttc gtaataagta
     6001 tgtttattat atagaaaaac cccatcctaa agaagataat gtctactata actttaaaga
     6061 tttagtagat gctatgaata ctgataaaaa tggtacattt aaacttggtg cagatttgaa
     6121 tgccactggt gttccaacac ctaagaaatg gtatgttgac ggcgacttta gaggtacatt
     6181 gaagagtgta gaggggaaac attatactat ccacaacacg gagcgtccgt tattccagaa
     6241 tattattggt ggtacagtaa ccaaagtaaa tctgggaaat gtaaatatca atatgccatg
     6301 ggcagaccgc atcgcaccga ttgctgacac tattaaaggt ggcgctaaaa ttgaagatgt
     6361 caaagtgact ggtaacgtat taggtagaaa ctgggtatct ggatttattg ataagattga
     6421 caaccaaggt acactcagaa atgtagcctt tatcggaaat gtgacatctg taggtgatgg
     6481 tggtcaattc ttgaccggta tcgttggtga gaactggaaa ggactagtcg aacgtgcgta
     6541 tgttgacgca aatcttattg gcaagaaagc caaggctgct ggtattgctt attggacaca
     6601 aaacagtggt gacaatcata aagttggtgt cgaaggtgca gtcaagaaag gaattgtgaa
     6661 gggtaccatt caggtagaaa gtcctgttga agtcggcggt gctgttggac gtttgagtca
     6721 tcatggttat atcggggaag tcgtatctat gatgaaagtt aagaagggtg aaatttttta
     6781 tggttctagt gatatgaatg atgacccata ttgggtggcg aataatgtac gaggaaatta
     6841 tgtagttaat ggtgtgagtg aaggtacgat atcttatgct cgtgctaaag aacaccatcg
     6901 tatcaaacca atttcacagt cagaagcaga tactaaaatt atgatgttag gtattacagc
     6961 acaagatttt gctgtcaacg aacctgtggt caatcgctta aaccgtttaa ccagaaaaga
     7021 agatgaatat aagtcaaccc aagactataa agtagatcga gatctggctt atcgtaatat
     7081 tgagaaactt caaccatttt ataacaaaga atggattgtc aaccaaggta acaaacttgc
     7141 agaagattca aacttagcta agaaagaagt cctttctgtt acgggtatga aggatggaca
     7201 gtttgtaact gacttatcag atattgataa gattatggtt cactatgctg atggtactaa
     7261 agaagaaatg gacgtcacta agaatgctga ttctaaagtg aaacaagttc gtgaatatac
     7321 catcgctgga caaaacgttg tttatacacc aaatatggtt gagaaagacc gtaaccaatt
     7381 gattcaagat atcaaagata agttggcgtc agttcaattg atttctcctg aagtacgtgc
     7441 tttgatggat gcacgtaaga aaccagaaga aaatactgat gaacgtaaga atggttatat
     7501 taaagacctt tacttagaag aaagctttgc tgaaacgaaa gctaatcttg ataaattggt
     7561 taaatcctta gttgaaaatg cagatcatca attaaatagt gacgaagcgg ctatgaaagc
     7621 acttgttaag aaggtggatg aaaataaagc taaaatcatg atggctctga cttatctcaa
     7681 tcgttactat gatatcaagt atggggatat gactatcaag aacttgatga tgtttaaacc
     7741 tgatttctat ggtaaatcag ttgaccttct tgatttcttg attcgaattg gatcaagtga
     7801 gagaaatatc aaaggtgaca gaactttgga tgcttatcgt gatatgattg gtggaactat
     7861 tggtaagtct gaattacatg gattcttaga ttacaatatg cgtctcttca ctaacgatac
     7921 tgatttaaat gattggttca tccatgcagc taagaatgta tatgtatcag aacctcaaac
     7981 aacgaaccca gattttgtta ataaacgaca tcgtgcattt gatggtttga acaacggtgt
     8041 tcataatcgt atgattctac ctctattaac tcttaagaat gcacatatgt tcttgatttc
     8101 aacttacaat acaatggctt atagttcttt tgagaaatat ggtaagtata cagaagaagc
     8161 tagaaatgaa ttcaaaaaag aaattgataa ggttgcacat gctcaacaaa catacttaga
     8221 cttctggtca cgtttagcat tgccaagcgt acgtgaccaa ttactcaaga gtgagaatag
     8281 ggtaccaact cctgtgtggg ataaccaaaa ctatagtggt attaaaggaa taaaccgtat
     8341 gggttatgat gagaagaaag taccaattgc gccaattcgt gagttatatg gtccaacttg
     8401 gaaattccat aataccaact ggaatatggg agctatggca tctattttcc caaatcctaa
     8461 taacaatgac caagtttatt tcatgggaac aaatatgatt agtccgtttg gtatttcagc
     8521 ctttactcat gaaactacac acgttaatga tagaatgctt tacttcggtg gtcatagaca
     8581 ccgtcaaggt acagacgtcg aagcctatgc tcaaggtatg ctacaaactc cgtcaagtat
     8641 tggtcaccaa ggtgaatatg gtgctttagg tttgaacatg gcttatcatc gtgaaaatga
     8701 tggtgaccaa tggtataact atgaccctga taagcttcaa actcgtgaag atatcgatcg
     8761 atatatgaaa aactataatg aagcactgat gatgctagat catgtagaag cagacgccgt
     8821 acttccacaa ttgaatggtg ataatagcaa gtggttcaag aaaattgata gagaaatgcg
     8881 cagaaatctt ggggatggtt tgaataactt agtagcaccg caccaatggg acaacgttcg
     8941 tgacttaaat caagaagaga gttctaagaa attatcaagt attaacgatt tgattgataa
     9001 taatttcatg accaaacacg gaaatccagg taacggacgt tatagaccag aggattttag
     9061 accaaactca gcttacgtaa atgtcaatat gatggcagga atttacggtg ggaatacgag
     9121 tcaaggtgct cctggttcat tatcgttcaa acataatgcc ttccgtatgt ggggttatta
     9181 tggatatgac aaaggtttca ctagttatgt atctagcaaa tatcaaggtg aagctgataa
     9241 acaaaaccag ggtagattag gtgatgattt cattatcaaa aaagtttcaa acaaccaatt
     9301 ctcaaatctt gaagattgga agaaatattg gtatcatgat gtgaaatcca gagctgaaaa
     9361 aggattcaca gagattacaa ttgatggaca aaccattcac aactataatg aactgaaaga
     9421 cttattcgac aaagctgtca cagaagacct caagaaagct ggaaactact caaatactga
     9481 gaatttgaaa tccaaagtct tcaaagctct tcttaaaaac acagacggtt tctttaatcc
     9541 attgttcaaa aaaga
//
LOCUS       DBEROT010000058         9483 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.58, whole genome shotgun sequence.
ACCESSION   DBEROT010000058 DBEROT010000000
VERSION     DBEROT010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.58"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            299..2227
                     /gene="glgB"
                     /locus_tag="ACL8CG_001943"
     CDS             299..2227
                     /gene="glgB"
                     /locus_tag="ACL8CG_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGS1344485.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2217..3359
                     /locus_tag="ACL8CG_001944"
     CDS             2217..3359
                     /locus_tag="ACL8CG_001944"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGS1344486.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVTTDED"
     gene            3349..4488
                     /gene="glgD"
                     /locus_tag="ACL8CG_001945"
     CDS             3349..4488
                     /gene="glgD"
                     /locus_tag="ACL8CG_001945"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGS1344487.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4485..5918
                     /gene="glgA"
                     /locus_tag="ACL8CG_001946"
     CDS             4485..5918
                     /gene="glgA"
                     /locus_tag="ACL8CG_001946"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGS1344488.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            6037..6348
                     /locus_tag="ACL8CG_001947"
     CDS             6037..6348
                     /locus_tag="ACL8CG_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HGS1344489.1"
                     /translation="MIDLLGREAGHEAEISQITSRAMRGELVFESSLRKRVSLLEGLP
                     ILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGFTPIVGEISKIPWYCLFHCQP
                     A"
     gene            6293..6622
                     /locus_tag="ACL8CG_001948"
     CDS             6293..6622
                     /locus_tag="ACL8CG_001948"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGS1344490.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERRVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            6631..7434
                     /locus_tag="ACL8CG_001949"
     CDS             6631..7434
                     /locus_tag="ACL8CG_001949"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGS1344491.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7431..7877)
                     /locus_tag="ACL8CG_001950"
     CDS             complement(7431..7877)
                     /locus_tag="ACL8CG_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGS1344492.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8041..9345
                     /gene="eno"
                     /locus_tag="ACL8CG_001951"
     CDS             8041..9345
                     /gene="eno"
                     /locus_tag="ACL8CG_001951"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGS1344493.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
BASE COUNT         2855 a         1679 c         2092 g         2857 t
ORIGIN      
        1 attttactat atataataca ttggagttaa aatagtacac tttgatttct aagacattgt
       61 tagaaattag attaaattcc ttaatcgatt tgcgcatgtt ttatttcatt ttactatagt
      121 ggaaaaagaa aggcgttttc gcaatttttt gaaaaaatat tgatttacaa ttgaacgagt
      181 aagtgaactt gttgtagatt ttcaaaataa ttaaagaagt atagtaattt acttgaatct
      241 tctctaaaaa ggtagtataa taaaaacata gaaaacgctt acaggagaag gggagtatat
      301 ggataataga gaagcattaa aaacctttat gacgggtgaa aatttttatc tccaacatta
      361 tctaggagca catagggaag aactaaatgg agagcatggc tataccttcc gtgtttgggc
      421 acctaatgct caggctgttc acttggttgg tgattttacc aactggattg aaaatcagat
      481 tccaatggta agaaatgatt ttggggtctg ggaagtcttt accaatatgg ctcaagaagg
      541 gcatatttac aaatatcatg tcacacgtca aaatggtcat caactgatga agattgaccc
      601 ttttgctgtc aggtatgagg ctcgtccagg aacaggggca atcttaacag agcttcctga
      661 gaagaaatgg aaggatggac tttggctggc acgaagaaaa cgttggggct ttgaagagcg
      721 tcctgtcaat atttatgaag ttcacgctgg atcatggaaa agaaattctg atggcagtcc
      781 ttatagtttt gcccagctca aggatgaact cattccttat ctcgttgaaa tgaactatac
      841 tcatattgag tttatgccct tgatgtccca tcctttgggc ttgagttggg ggtatcagct
      901 tatgggttac ttcgctttag agcatgctta tggccgacca gaggagtttc aagattttgt
      961 cgaggagtgt catacccata atattggggt tattgtggac tgggtaccag gtcactttac
     1021 catcaacgat gatgccttag cctattatga tgggacaccg acttttgaat accaagacca
     1081 taataaggct cataaccatg gttggggtgc ccttaatttt gaccttggaa aaaatgaagt
     1141 ccagtccttc ttaatttctt gcattaagca ttggattgat gtctatcatt tggatggtat
     1201 tcgtgtggat gctgttagca acatgctcta tttggactat gatgatgctc catggacacc
     1261 taataaagat ggcggaaatc tcaactatga aggttattat ttccttcagc gcttgaatga
     1321 ggttattaag ttagaatatc cagatgtgat gatgattgca gaagaaagtt cgtctgcgac
     1381 caagattacg ggaatgaaag agattggtgg tctaggattt gactacaaat ggaacatggg
     1441 ctggatgaat gatatcctcc gtttctacga agaagatccg atctatcgta aatatgactt
     1501 taacctggtg actttcagct ttatgtatgt tttcaaggag aattatctct tgccattctc
     1561 gcacgatgaa gtggttcatg gcaagaagag tatgatgcat aagatgtggg gagatcgtta
     1621 caatcaattt gcaggcttgc gcaatctcta tacgtaccaa atttgtcacc ctggtaagaa
     1681 attgctcttc atgggtagcg aatacggtca attcctagaa tggaaatctg aagaacagtt
     1741 ggaatggtct aacctagaag acccaatgaa tgctaagatg aagtatttca cttctcagct
     1801 aaaccagttt tacaaagatc atcgctgtct gtgggaaatc gataccagct atgatggtat
     1861 tgaaatcatt gatgcggata atcgagacca gagtgttctt tcctttattc gtaagggtaa
     1921 aaagggagaa atgttagtct gtatctttaa catggtacct gttgagcgga aagattttac
     1981 aatcggacta cccgttgcag gaatttacga agaagtatgg aatactgagt tggaagagtg
     2041 gggaggcgtt tggaaagaac ataatcaaac tgttcaaacg caagaaggac tatggaaaga
     2101 ttatgagcag accttaacct ttactctacc ggctatggga gcaagtgtat ggaaaatcaa
     2161 acgtcgcttg aaatctacta aaaccgtcac aaataaaaac caaaaaggag tagaaaatga
     2221 aaaatgaaat gttagctttg attcttgctg gtgggcaagg aactcgtctc ggtaaactca
     2281 ctcaaagcat cgcaaaacca gctgtgcaat ttggtgggcg ctaccgtatc attgactttg
     2341 ccctatcaaa ctgtgccaac tcagggattc ataatgttgg ggtcgttaca cagtatcaac
     2401 cacttgctct caacaaccat attgggaatg gttcaagctg gggactagac ggtattaatt
     2461 caggtgtctc tattcttcaa ccttattctg caagtgaagg aaatcgttgg tttgagggga
     2521 ctagtcacgc tatttaccaa aatatcgact atatcgacag tgtcaatcct gagtatgtct
     2581 tgattttgtc tggggatcac atctacaaaa tggactatga tgatatgctc cagtctcata
     2641 aggataataa tgccagcttg acagtagcag ttttagacgt ccctcttaaa gaagcaagcc
     2701 gttttggtat catgaacaca gatgctaaca atcgtattgt tgaatttgaa gaaaagccag
     2761 ctcaacctaa atctacaaaa gcttctatgg gaatctacat ttttgattgg caacgccttc
     2821 gtaatatgtt agtcgctgct gaaaagagca aggttggcat gtcagacttt ggtaaaaatg
     2881 tcattccaaa ttaccttgag tcaggtgaaa gtgtttatgc ttacgaattt agtggttatt
     2941 ggaaagatgt tggtactatt gagtcacttt gggaagcgaa catggagtat atttctccag
     3001 aaaatgcctt ggatagtcgt aaccgtcaat ggaagattta ctcaagaaac ttgatttcac
     3061 caccaaactt cctcggggca aatgctcatg tagaagactc attagttgta gacggatgtt
     3121 tcgttgatgg aactgttaaa cattctatcc tttcaacagg cgcgcaagtt cgcgaaggag
     3181 cggaagtcct tgattcagtt atcatgagtg gagctatcat tggtcaagga gctaagatta
     3241 aacgtgccat tattggtgaa ggtgcgatta tttctgacgg tgtcgaaatt gatggaacag
     3301 atgaagtaca agttgtagga tataatgaag tagtgggggt aacaacagat gaagattgat
     3361 aaatattctg ccattttagg aaatacagtt ggttttcaca atatgtcgac attgacggac
     3421 caccgtccag tagcaagttt gccatttggt gggaaatatc gtttgattga cttcccactt
     3481 tcaagccttg ctaatgcagg tgttcgtagt gtctttggta ttttccagca ggataatatc
     3541 agctcagtat ttgaccatat tcgttcagga cgcgagtggg gcttatcaac ccttcttagt
     3601 cattactatc taggaattta caatacccgt gtagaaagta gtacagttgg aaaagaatac
     3661 taccaacagc ttcttactta tttgaaacgt tctggctcaa accaaacggt tgccctcaac
     3721 tgcgatgttc ttattaacat tgatttgaac caagttttcc acctacatag tacaacaaaa
     3781 gagcctatca ctgtagttta taaaaaacta gctaagaaag atatttcaga agtaaatgca
     3841 atcttggatg tagatgaaac agaccatgtt ctttctcata aactctttga tagcaagtca
     3901 acagctgaaa cgttcaatat gtctacagat atctttgtcg ttgatacacc ttggttgatt
     3961 gaacacttgg aagaagaagc taaaaaagaa catccaaaga aattgcgcta tgttttacgg
     4021 gatttggctg taaaagaggg agctttcgcc tacgagtaca cgggctatct agccaatatt
     4081 cactctgtta aatcttatta tcaagcgaat atcgatatgc ttgaatcaca aaaattctat
     4141 tctcttttct caccaaacca aaagatttat acaaaggtca aaaacgaaga gccaacttac
     4201 tatgctaata catctaaggt aagcacttct cagtttgcct ctggtagtat tattgaaggt
     4261 caagtagcta attctgttct atcacgtaat attcatgtcc ataaggatag cttggttaaa
     4321 gatagcctgc tcttccctcg tgttgttatt ggagaagggg ctcaggtcga atatgctatc
     4381 ttggacaaag gggttgaagt tgagcctggt gttgtgattc gaggaactgc agaacatcca
     4441 gttgtggtta agaaaggtgc taaagtaaca gaggatattc attcatgaaa attttatttg
     4501 tagcagcaga gggtgcaccc ttttcaaaaa caggtggttt gggagacgtc attggcgctc
     4561 ttccaaaatc actggtaaaa gctgggcacg aagttgcagt gattttaccc tactatgata
     4621 tggtagaggc taaatttgga aatcagattg aagatgtact tcattttgag gtgagcgttg
     4681 gttggcgcag acagtattgt ggaattaaga aaacagtatt aaatggtgta accttctact
     4741 ttattgacaa tcaatattat ttcttccgtg gtcatgttta cggtgatttt gatgacggag
     4801 aacgctttgc ctttttccaa ctggctgcca ttgaggctat ggaaaggatt gactttattc
     4861 ctgatcttct ccatgttcat gactaccata cagctatgat tcctttcttg ttgaaggaaa
     4921 aataccgttg gattcaagcc tatgaggaca ttgaaacagt tttaaccatt cataatttag
     4981 aattccaagg acaattttca gaaggaatgt tgggtgattt gtttggagtt ggctttgaac
     5041 gttacgctga tggcaccctt cgatggaaca actgtctgaa ctggatgaag gcaggtattc
     5101 tctatgcgaa ccgtgtttca accgtttcac ctagctatgc tcatgaaatt atgactagtc
     5161 agtttggatg taatttggat cagattctta aaatggagtc tggtaaagta tctggtatcg
     5221 tgaatgggat tgatgctgat ctttataatc ctcagacgga tgctctttta gactatcatt
     5281 tcaatcagga agatttgtct gggaaagcca aaaataaggc aaaattgcaa gaaagagttg
     5341 gcttgcctgt tagagcagac gttccactgg tgggaattgt ttctcgtttg acacgtcaaa
     5401 aaggttttga tgtggtggtc gaaagtcttc accatatctt gcaagaagat gttcagattg
     5461 ttcttttggg aactggcgat ccagcctttg aaggagcttt ctcatggttt gctcagattt
     5521 acccagacaa gctatcagca aatatcactt ttgatgtcaa acttgctcag gaaatctacg
     5581 ctgcttgtga cctcttcctc atgccaagtc gttttgaacc gtgtggcttg tctcaaatga
     5641 tggctatgcg ttatggaacc ttgccattgg tccatgaagt tggaggcttg cgagatacag
     5701 ttcgcgcttt caatccaatc gaaggaagcg gtactggctt tagctttgac aatctatctc
     5761 cttattggtt aaattggact ttccaaacag cattggactt gtatagaaac catccagaca
     5821 tttggagaaa cctacaaaaa caagctatgg agagtgactt ctcatgggat acagcctgca
     5881 agtcatacct tgacttgtac catagtttag ttaattaata gataaaatcg tatgatgact
     5941 tcatacgatt tttaggctgt ttagagagga gaactgatgt ctcaagtaaa aggcttgtgt
     6001 gttttggatg tagatggaac cttaatccta gaataagtga ttgatctttt agggagagag
     6061 gcaggtcatg aggcggaaat ttcgcagatt acaagtcggg caatgcgagg agagttggtc
     6121 tttgaaagca gtttaagaaa aagagtgtcc ttgttggaag gtcttcctat tttggtcttt
     6181 gataacgtct tcaactcaat tcatctatcg ctaaatgtcc cagagttcat ctctattctc
     6241 caaaagaatg gcatcctagt tggtctggtg tctggtggat ttacaccaat agttggagag
     6301 attagcaaaa tcccttggta ttgcctattt cactgccaac cagcttgaag tcaaagaagg
     6361 tcttttaaca ggaaaattag ttggacaaat tataagtccc caggtcaaaa aagagactct
     6421 ggaaaaatgg agaaagaaac taaaactttc taaagaaaga agggtggcaa tcggtgatgg
     6481 ggttaataat ctattaatgt tgaagtcggc ggagttagga atcgcctttt gtgccaaaga
     6541 agtgctcaaa aaagaaatac cacatcatgt tgacaagagg gattttttag aagttcttcc
     6601 tttgattgac tgtttagaat gagggaaaat atgaagattg taattgcacc ggattcgttt
     6661 aaggaaagct tgacagctca acaggtagct gaagcaataa aaagaggctt ccaacaatcg
     6721 atagcagatg tagaatgtct cctctgccct gttggtgatg ggggagaagg tactgtagat
     6781 gctatccgac attctcttga cctaaaagaa aaatggatcc aagtgacaga cccttctgga
     6841 caaaaagaag ccatgcgcta ttttcaaaaa ggggaactgg cactatttga agtagctgac
     6901 ttggttggtc ttggaaaaat tccgctagag aaacgaaatc cacttcaaat ccaaacttgt
     6961 ggtattggag agttgattct ccatctcatt tctaaaggga ttaaagatat ttatatcggt
     7021 gttggtggca cggccagtaa tgatggagga ctggggattg ctgctggttt gtgtgccttt
     7081 gctcaggcaa gtatcgtgtc tggaattgat acctgcttgg acttaatcaa ctttgataag
     7141 aaggtttcag atgctgactt ggttgttgtt ggagaaggaa gacttgatag tcaaagcttt
     7201 gctgggaaag cgcctatagg tgttgcaaaa agaacccctg ttggagttcc tgttattgct
     7261 atttgcggta gtcttgctga agatttacct cccctaccat ttgaaaatat ccaagctgtc
     7321 ttttctattt tggagaaaag tgaaccttta gaagatagtt tgaaaaatgc cagtctctat
     7381 ctggagcgca cggctgccaa tattgggcac ttattaaata tgtgcaagat ttagctaaac
     7441 catttcttcc ataaggatgt tttggctggt tcttcctttt taacttccca aagttttgga
     7501 aaagcaagtc gaaggtcttt ttcttctact tgaactggtg cattgctatg aataaccagg
     7561 ccaaaaggag aagtaatatg ctcttcagat actatggtgg cttgactatc agtttctttt
     7621 gcttctttta agtagaaaac ttgcttatca aattcgatag ttggtgaaat cttcacaaat
     7681 agtggctctg ctttttcctg aaggttttct aaaataaata aaaagccttt ttctaactga
     7741 gggctatttg ctgtgtcaat atctacatat ccaagaactc tttcctcaaa agtaccaaga
     7801 tagcgtcttt gctcatccgg atttattttt aacccaccat gagctttttc aagtaattgt
     7861 tttgataaat ctgtcatgaa aacagtatat cataaaagtt agaataaaac agacaaaaga
     7921 aagcgattac tttataaagt taaggaaaag ttgcacaaag ataacgtttt ttcttgaaaa
     7981 aggaggggtt ttaaggtatt atagaggtgt aaaaaattta actcataagg agagtaaaaa
     8041 atgtcaatta ttactgatgt ttacgctcgc gaagtcctag actcacgcgg taacccaaca
     8101 cttgaagtag aagtttacac tgaatcaggt gctttcggac gtggtatggt tccatcagga
     8161 gcttctactg gtgaacacga agcagttgaa cttcgcgacg gtgacaaatc tcgttacggt
     8221 ggtcttggta cacaaaaagc tgttgacaac gtaaacaaca tcattgctga agctatcatt
     8281 ggctacgatg tacgtgatca acaagctatt gaccgtgcta tgatcgcact tgacggtact
     8341 cctaacaaag gtaaattggg tgcgaatgca atcctcggtg tgtctatcgc tgtagctcgt
     8401 gctgctgctg actaccttga aatcccactt tacagctacc ttggtggatt caacactaaa
     8461 gttcttccaa ctccaatgat gaacatcatc aacggtggtt ctcactctga cgctccaatc
     8521 gctttccaag agttcatgat cttgccagtt ggtgcgccaa catttaaaga agcccttcgt
     8581 tacggtgctg aaatcttcca cgctcttaag aaaatcctta aatcacgtgg tttggaaact
     8641 gccgtaggtg acgaaggtgg attcgctcct cgtttcgaag gaactgaaga tggtgttgaa
     8701 actatccttg ctgcgattga agctgctgga tatgtaccag gtaaagacgt atttctcgga
     8761 tttgactgtg cttcatcaga attctacgat aaagaacgta aagtttacga ctacactaaa
     8821 tttgaaggcg aaggtgctgc tgttcgtaca tctgcagaac aaatcgacta ccttgaagaa
     8881 ttggttaaca aatacccaat catcactatt gaagatggta tggatgaaaa cgactgggat
     8941 ggttggaaag ctcttactga acgtcttggt aagaaagtac aacttgttgg tgacgacttc
     9001 ttcgtaacaa acactgacta ccttgcacgt ggtatccaag aaggtgctgc taactcaatc
     9061 cttatcaaag ttaaccaaat cggtactctt actgaaactt ttgaagctat cgaaatggct
     9121 aaagaagctg gttacactgc tgttgtatca caccgttcag gtgaaactga agattcaaca
     9181 atcgctgata tcgcagttgc aactaacgca ggacaaatca agactggttc actttcacgt
     9241 acagaccgta tcgctaaata caaccaattg cttcgtatcg aagaccaact tggtgaagta
     9301 gctgaatatc gtggattgaa atcattctac aaccttaaaa aataaaatag ttcagtgaac
     9361 tattttatcc cgaaccatga aattcaaaag ttcggccgtt gatttaacaa cgtttctagc
     9421 ccctcggatt ttatccgaag ggctattttt gtatttagag ggcaaaaaag ggacaaaact
     9481 ttt
//
LOCUS       DBEROT010000059         9380 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.59, whole genome shotgun sequence.
ACCESSION   DBEROT010000059 DBEROT010000000
VERSION     DBEROT010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9380
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.59"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            279..491
                     /locus_tag="ACL8CG_001952"
     CDS             279..491
                     /locus_tag="ACL8CG_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344494.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            864..989
                     /locus_tag="ACL8CG_001953"
     CDS             864..989
                     /locus_tag="ACL8CG_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344495.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            970..1215
                     /locus_tag="ACL8CG_001954"
     CDS             970..1215
                     /locus_tag="ACL8CG_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344496.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            1372..2430
                     /locus_tag="ACL8CG_001955"
     CDS             1372..2430
                     /locus_tag="ACL8CG_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344497.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2745..3722
                     /locus_tag="ACL8CG_001956"
     CDS             2745..3722
                     /locus_tag="ACL8CG_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344498.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLILFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            4099..4473
                     /locus_tag="ACL8CG_001957"
     CDS             4099..4473
                     /locus_tag="ACL8CG_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGS1344499.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALPAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4480..4662
                     /locus_tag="ACL8CG_001958"
     CDS             4480..4662
                     /locus_tag="ACL8CG_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344500.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWINVV
                     FLILIIAMMIYPKLRK"
     gene            4681..5583
                     /locus_tag="ACL8CG_001959"
     CDS             4681..5583
                     /locus_tag="ACL8CG_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344501.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            5639..5992
                     /locus_tag="ACL8CG_001960"
     CDS             5639..5992
                     /locus_tag="ACL8CG_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS1344502.1"
                     /translation="MDLVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            5989..6717
                     /locus_tag="ACL8CG_001961"
     CDS             5989..6717
                     /locus_tag="ACL8CG_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344503.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            7196..7393
                     /locus_tag="ACL8CG_001962"
     CDS             7196..7393
                     /locus_tag="ACL8CG_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344504.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            7850..8089
                     /locus_tag="ACL8CG_001963"
     CDS             7850..8089
                     /locus_tag="ACL8CG_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344505.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            8074..8352
                     /locus_tag="ACL8CG_001964"
     CDS             8074..8352
                     /locus_tag="ACL8CG_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344506.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            8638..>9380
                     /locus_tag="ACL8CG_001965"
     CDS             8638..>9380
                     /locus_tag="ACL8CG_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344507.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKSEAAKKHYEEVKKKAEDAQKKYDEGQKKTVEKAKREKEASEKIAEATKEV
                     QQAYLAYQQASNESQRKEADKKIKEATQRKDEAEAAFATIRTTIVVPEPSELAETKKK
                     AEEAKAEEKVAKRKYDYATLKVALAKKEVEAKELEIEKLQYEISTLEQEVATAQHQVD
                     NLKKLLAGADPDDGTEVIEAKLNKGEAEL"
BASE COUNT         3181 a         1193 c         1704 g         3302 t
ORIGIN      
        1 ttttaggata tcttttagtg attcaaaaag caggctattt gttttcggtt ttacttcttt
       61 tttctaattt ttcagttcca tttatcaaag caaaggaata cgaattattt aaaaataaga
      121 aatgagatag atatggtagc tttattaaaa ctgagaataa agtttgggag atatttttat
      181 ttattttagg tgtgttgtta attgtaattt cattactaag tcccccaaaa attaaatttt
      241 ggaaatagag ttagtgagaa ggataggata atagtattat gatggttgtt ttaatttcag
      301 ttattgttgc attcctgtat cataaaatta cagagtatgt caacaacagg aaaattgata
      361 ttgttatttt tctatcattg ctgatttctc attttatttg gaattactat tttttaccaa
      421 ttgaaatatt gatagcaatc agtggagcaa atttactatt aagtttttta aaaaaattac
      481 agactaaata atattaatct gtgtaataca gtagctcggt cattagattc tattgaagat
      541 ataaattaaa aatgaggctg ggaaaaaact caatttgaaa atgaaattga gtaaattttt
      601 ctattatata acgcatatta tcaagatttt tgaacacctg ataatatgca cttttcttat
      661 tttaaagatt ttttgccttt cttcatttct tggatgaatt ggagagatga cttgatttag
      721 gtgtttgaca ttactataga taggatttag cagtactaat atgaactcat attataggtg
      781 tagacttaaa ttttggaagc aagctaaagg atatcttatc taggtaacta agtgctataa
      841 caagatatat tggtggagtt agtatggcaa ctattactaa tgctcttaat attgcggcta
      901 ctgttgctga agtcttctca ttaggaggag ccattgcata tggtttagat atcgtagacg
      961 gtaaatttga tgggtattta tgggcgtaaa actatagcta tgaaacattt ttttgcagga
     1021 attggtgaaa ttcatttttt gttattttta ttatatctaa gcatgtctgc tagtccaatt
     1081 attggactag tgattggata tactaaaata aatctaataa attctattat tatagctctt
     1141 ggtatgatat tggcattaat tttggtatta tcaagagtgt atagaaaata tttttataga
     1201 gacgatgatg actaaagttt ttatcaataa tttgggctcc ttgtcaactg tagtgggttg
     1261 aataaaagct aacgtctggg gaagggttta aagctttgct ttatcaaata ttgacttaca
     1321 gagttgctct attgtattga tgtattctta gtaaataata tggtgttttg aatgaaagat
     1381 gatcagaaat atttattagc gggactttat tcgcttctag ttgcaatatt ttattttcca
     1441 ttgattgatt ccaaggggat ttttgtaagt atattgatgg cggttttact tttatattta
     1501 atatacttca ttgcaacagt cattcatatt gtgataatta agtttataag aaaaaaatct
     1561 tttaagtatt tggttctata tccatttact tacgatggga gctggagatt tcagcctata
     1621 aacttactct actttccaga aatggtgaga gatgtcattc cgattaattt agttcaagaa
     1681 tattgccaag gacaacctta cggactgtta aaaaagatgc tgaaaagaat tcgattgtca
     1741 cgagagatat ctttactcct ggctaccatt atcgtctatt tttttacgca tagaattcta
     1801 cctctttcag tatttacgtt catgttctct tacatattgc tatttgtaca atcttatttg
     1861 ggtagcaata ccgcttggat tggaaataga agattaataa tagatgatga atttgaaaaa
     1921 atcttgcttt caaaaagtta tgtaaaagaa atatcatctg cacgatactc agaatacttg
     1981 acatgtgaat acaaaaacct tacaccaatc atattgatag ctatttttga aaatttgctt
     2041 gactcctact tgcttcagaa tcagagtgag gttgacttag atatttttta taaagtttta
     2101 cctttgcttt ataaagaaaa atatactatg ggattcaatt actttgtaag tttaaattat
     2161 ttactatata aggttggatt tttgggaatc atttacgata atgaagcatt aagagatttg
     2221 tcaaaacaat atttaaacaa aaatatttcg gaattacaag atggttcttt cgagggcggt
     2281 atacaagatg ctgttgcctc taaacaaata gtagttataa atgaatttat agcttgttta
     2341 aattccagat gcgtgccatc ccaatatgat agattttttt ataaagatag accttatatt
     2401 ttttccagaa agagtcctat taaggggtga aaatttgtta catttggatt aacaagtgtc
     2461 ctagggatta gaaataactc tagtatagct agatattttt gagtaactag aaatatcatt
     2521 aggctaccca tatgattgcc agaaaagatg gctgatgaat cttatttata ctgttgcagt
     2581 aggcattgtc taggataaat aagctatctt gatgggggag attggaataa ttttagtaga
     2641 aacattaaag gattatggac aagtagcgta ggattaggtg atgcaatgtg ctaagttggc
     2701 ttggtgttag cagtagtatt atttaacaat ggaaagtaga ctaaatgaaa aataagcgtt
     2761 atttttttga cacaatttta ataattttac tgcttataag cacgatattt tgtgtcagcc
     2821 cagtatttat aaaattggac atcttaggaa ctccctctca tgccatctta acctttgtat
     2881 tggcgatacc gttattctat attttgtctc aatgcttaca tactttgcta ttactagttt
     2941 cctcaatctt ttgtaaatta agaccaattt atttttattt tatatttgtg atcattatag
     3001 gagctaggaa atactatcga attctctttc accaactaat gggatttagt ccaggaatag
     3061 cagtgtttta taaggagagt caaacaacta agaatctgtt taaattttac tacttcttgt
     3121 actttacaac actaatttca tactattttt tctttacttt tgtgtatgac aaaccgttgc
     3181 ttttgcctct tattttattt tctattatca tagcattagt acaaaaactt tatagaattg
     3241 agaatcaaca attatttctg ttaaaatcaa aggtactaac aatactggaa tctaagaaga
     3301 attgtgagtt taatcttcag gattatcatg aaatttggaa attgcaatca aaatctgagt
     3361 tgccatgcgt ggctttatct tatatcagtt taatcaagcc atatctttca gagagtgtgc
     3421 gtgaacaaat tgatttatta gaagttaagc gatttaaaaa aataaatcat ccaatatcac
     3481 tttatggtat gttggatgtt ataaaattaa atctatattt acggcattat aatgaaaaaa
     3541 ataaatatga atcaatgtta aagaaaattt tagaggtaag accagacttt gttttaatcg
     3601 agcagaatat tgatgatagt ttaaatagct cgcaaccatt atctttatct ttagccattt
     3661 cagaaatcca acttttgctt gaagtgtata tagggatcaa acatgtttca attaggagat
     3721 aaaactagaa taatatttgc cattataggg gcaagttgca tattagtcag tatgtatctt
     3781 attccactta ttaaaactga gaataaattt tgggaaatac ttttatttat attaggtgta
     3841 ttgctaattg gaattgcgtt actaagtcaa aaaaaataaa ttttgaaata gtattagtga
     3901 gttcgcaatc atttattgct agtggtttag aactgttaag tttcaaacaa taattgattt
     3961 taaaccttag gtaacctata aaaacaaata aggtagagaa aggatatctt atctaggtag
     4021 ctaagtgata aaaacacagt cgtctatcac ttgttaggaa actatcctaa ctatgcttaa
     4081 taaaaaagga gaaaataaat ggaactcgta ttaccaaata attatgttgt tcttgagcaa
     4141 gaagagatga tgtatcttga tgggggattt tctattccga gatggcctgt tgcaacagcc
     4201 attaatatag cttttaatgg tgttttaggt ggaggagcaa tcagtctagt tagaaattat
     4261 attcgtaatt atggtttgcg gcgagttaca agcgcaattg ctggagcagc tgcaagatat
     4321 gttggggtac gagttgcaaa tagagtggca ggatttgcac tgcctgctat taatggattt
     4381 gcagcttgga tgtcaattgg cgatgctatt acaacaatct gggccaataa tgatgtaaat
     4441 aggagagacc caaatttaaa cgccttgtgg taactagata tgggtattaa aatggaaaaa
     4501 atttttgtta ttattttttt tgtatgtcta tttatatcat ccataacttt tttagcctat
     4561 gattttgtta gcgaagaaat aaaaaagttg attatttgga ttaatgtcgt ttttttgatt
     4621 ttaatcatag caatgatgat ttatccaaaa ttaagaaaat gataaggaca ctgtaaaatt
     4681 atgatacgta aactaattgt tttcttacta atgctccctc tttttgtctt gtggctagag
     4741 ttgcatgtcc tagtgaataa cttactattg aatctagaat ctccccttga ttttgtgatt
     4801 agtatgagtc ttgctttctg tagtttgatt ttatcaaaaa tagttttaga catactatac
     4861 gcattgaaag atttatacaa gaaagaaggt cttattaaga tttttccctt tatttttata
     4921 agaaggaaaa aagtgaatgt gagattctcg ccctattttt cattccatcg taaaagtttg
     4981 tcgcctgatg atttaagatc taggattata tggagtttta ttcttgaaat tgctattatc
     5041 ctagtattta ttttaaaaat tccttttgca atcatcatgc ttactacaat atttttctgg
     5101 actataatgg atatcaatca tctcgttttt aataagacgg aatttctttt caatcaaaat
     5161 aaatgggaaa aagaagattc gtttgaaagt gatttgacaa atacgttaaa ggataaaata
     5221 caaaaatcag atctcagtta ttctgactta atgtctcttc agctgtatga tgcgatgaac
     5281 caatccacct ttttaacgga tagtgaactc tttgaggata ttctgagtaa aattgaagat
     5341 tctcataaca cccttctgtg tacaggtctt gtcgagttac tgctgtatga gatttctatt
     5401 agtaacaata acaactggca agaaaaggtt gataaaatta gaatacagct catcagaata
     5461 aatcaattag attttttcta ttatacaagt tggttaaggc aaaattttga tttctgtatg
     5521 aatagagagt atcataaaat gaaatctcgg aaattattac tgagtaataa aaagatagtt
     5581 taagttcgtc ctatttgtaa aacaaatgaa acaatttcaa ctaaggagga gaaaacttat
     5641 ggacttagta ttaccaaata attatgttgt gattgatgaa gaagaaatga tgtatcttga
     5701 tgggggagct tatttaagca agcgtgcttg tcaaggaatt tgcgcagctt tagctatgag
     5761 ttcaggaact tttatagcat tagctggagc tgcagtttta accaaaaaac taataaacta
     5821 tattaaggtt ggaggtcttg gaggctggct tattggtgca gcagcaggtg tattggctac
     5881 agcagcaggg aaaatagctt actgtattgg atatggtgtt cttaatagag gttgtgatat
     5941 taacgggaac ccttatcctt gggatggatt catatctgca acagtaagat gagtaatgta
     6001 gataagattc gaaaaataca catcatcgtg tgttgggtgt atatattttt atcattcagg
     6061 gcgattataa atgatacgga gtattttttg cttatttttt tagcttttat ctactcaata
     6121 gtatcactac ctctatattc tgtgaaaaat aaaatagtat ctatctgtct agccataaat
     6181 tcgattctgt taatgagttt ccccatttta atcaataagt ttttcccaga aagttttttg
     6241 acttataccg tattaataag tgtttttatc ctagagttag caatctttca tttaattggg
     6301 gaagattttg ctactaaatt gactaacgaa tataagaaaa ttagtcagtt tagaagcaag
     6361 gtgtctcaat ctccttggat aaaatattta gagatttcta gttttatatt aactatattt
     6421 ccatctattc tttacggtac agttgataat cgtgtattgg ctcttatctt tttgataaaa
     6481 atttgtgtag atactacgat aaaattttta ttcatcagat tatttgacac aagtacttta
     6541 atgaagagga gaatattttt tcttttcgca ttggatgtta tagcttactt atttttagga
     6601 tatcttttag tgattcaaaa agcaggctat ttgttttcgg ttttacttct tttttctaat
     6661 ttttcagttc catttatcaa agcaaaggaa tacgaattat ttaaaaatag caagtaatag
     6721 aaacataggt taaatcttag aacggcttaa aatcagatat gataaaggga aatagtctta
     6781 tctaggtaac taagtgctac aaacacagtc gaggatcact tgttaggatt acattttaat
     6841 catgcttaat aagaatggag aattcctatg gggattgtat tactctgaag tttcgaatac
     6901 cttagttctc gtgattttga gctgttctag ctttagaatc cttcagaatg taaaatttta
     6961 agcagtcaaa gacttagaat agcctggaaa catttatttt atagcaattc taggcttaga
     7021 attgctcata tatatgtatt tgagctgctc gatagttagg acagctctat tctgagaaat
     7081 ctgagctatc aatgcttcag aatagtattt cgcaaatggt ttttattgaa gaggtgattg
     7141 ttttatgata gtctaaaata aaactgattt aatggagtaa atggagaatc gtcacatgaa
     7201 acattttttt gcaggaattg gtgagataaa acttgttggc tacttattgt atatatgtgt
     7261 aggactagcc cctctttttc atatatatgt cataggttcg gaactgagtt ttgtgaaaat
     7321 agtgttatct attttgggag ttatatttgt aagtatgtta actattgctc gaatttatcg
     7381 gacttttcta taaagaatag tttggacttg aactgtatct aaaaacagag gttggtcgat
     7441 tatcagcctc tttcttgtcg ttgaaaagag tgagatatat tgacttttga aaaaaatgtc
     7501 ataattgagt tgggataaac ctaaaagtaa tatagtagat tgaatctgga atagtccgtt
     7561 atgactgtta aaatatttct agaaattaat ttgactttcc taatcgattt gttcacatct
     7621 tgtttcaatc tactatactt tctcgttaaa ccgttcggca attcatggtg acatggacac
     7681 atagtagtaa gcacactatg tggcttggca gagctaaaaa ctgttccctt gcgataagcc
     7741 taataagcac aacataggga gttagagaag ccgactctaa tcaaccactt tgggcagtag
     7801 tgagaactgc cccgtgcttt tttattttga gaaaatatgg agtttgtcgt tgaaattact
     7861 tgattgtatt ttggactatc aagaaagatt caatggaaaa acatgtcaag tatcaacgaa
     7921 ttataagtat ttagagattt tcaaagtgaa tttttgcttg actgatttac atcatttatt
     7981 tgacttatac aaaatcacac gagattatgc tagtcaaaca aaacctgcta ttcaagctgg
     8041 tgtttttatt ttagaagatt ttagaaatat cctatgtaca atgatgtaat cgaaaggata
     8101 tctttatatg agtttatcgg tgatattttc tattctaaaa taataagttg ttgcatcgta
     8161 gctagggatt tatctaaaaa tactatgaaa ttggacgtca tattttttga ggataaaaat
     8221 aaaagatccg cagttttagg tttacgaaga gacaaaagcg gagtatttaa atcagttact
     8281 ctacatttta caagcgctaa gaaatatgct aaagttcgta aaacagatgt gaaagaaatg
     8341 aaatggctat aaagattgtc cgcaggctta agcttgcgtt ttttgttgtt taacgaaatt
     8401 aaaaaataag ctctctcatt ggaaatgttt ttataggaat gaaggaagat gatgctatgt
     8461 ttaaaaagag aatcgaaaag ggcaaaagta gtgtctttat ctttttggag tagaagctta
     8521 tgatatagaa atttgtaata aaaatgtaat ataaaacatt tgacaaatat ttacgggggg
     8581 agtatactta atataagtat agtctaaaaa tgactatcag aaaagaggta aatttagatg
     8641 aataagaaaa aaatgatttt aacaagtcta gccagcgtcg ctatcttagg ggctggtttt
     8701 gttacgtctc agcctacttt tgtaagagca gaagaagctc ccgtagctag tcagtctaaa
     8761 gctgagaaag actatgatgc agcagtgaaa aaatctgaag ctgctaagaa acattatgaa
     8821 gaagttaaaa agaaagcaga agacgctcag aagaaatatg acgagggtca gaagaaaacg
     8881 gtagaaaaag caaagcgaga aaaagaagct tctgaaaaga tagctgaggc aacaaaagaa
     8941 gttcaacaag cgtacctagc ttatcaacaa gctagcaacg aaagtcagag aaaagaggca
     9001 gataagaaga taaaagaagc tacgcaacgc aaagatgagg cggaagctgc atttgctact
     9061 attcgaacaa caattgtagt tcctgaacca agtgagttag ctgagactaa gaaaaaagca
     9121 gaagaagcta aagcagaaga aaaagtagct aagagaaaat atgattatgc aactctaaag
     9181 gtagcactag cgaagaaaga agtagaggct aaggaacttg aaattgaaaa acttcaatat
     9241 gaaatttcta ctttggaaca agaagttgct actgctcaac atcaagtaga taatttgaaa
     9301 aaacttcttg ctggtgcgga tcctgatgat ggcacagaag ttatagaagc taaattaaac
     9361 aaaggagaag ctgagctaaa
//
LOCUS       DBEROT010000060         9103 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.60, whole genome shotgun sequence.
ACCESSION   DBEROT010000060 DBEROT010000000
VERSION     DBEROT010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.60"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..129
                     /locus_tag="ACL8CG_001966"
                     /pseudo
     CDS             1..129
                     /locus_tag="ACL8CG_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263494.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(263..1231)
                     /locus_tag="ACL8CG_001967"
     CDS             complement(263..1231)
                     /locus_tag="ACL8CG_001967"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS1344508.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1376..2191)
                     /locus_tag="ACL8CG_001968"
     CDS             complement(1376..2191)
                     /locus_tag="ACL8CG_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HGS1344509.1"
                     /translation="MKKSSILFIFILLLCIDLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2216..2713)
                     /locus_tag="ACL8CG_001969"
     CDS             complement(2216..2713)
                     /locus_tag="ACL8CG_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGS1344510.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2786..4147)
                     /gene="radA"
                     /locus_tag="ACL8CG_001970"
     CDS             complement(2786..4147)
                     /gene="radA"
                     /locus_tag="ACL8CG_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGS1344511.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSTNVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4161..4676)
                     /locus_tag="ACL8CG_001971"
     CDS             complement(4161..4676)
                     /locus_tag="ACL8CG_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1344512.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4678..5121)
                     /locus_tag="ACL8CG_001972"
     CDS             complement(4678..5121)
                     /locus_tag="ACL8CG_001972"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGS1344513.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5178..5275)
                     /gene="ffs"
                     /locus_tag="ACL8CG_001973"
     ncRNA           complement(5178..5275)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL8CG_001973"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5308..5775)
                     /gene="tadA"
                     /locus_tag="ACL8CG_001974"
     CDS             complement(5308..5775)
                     /gene="tadA"
                     /locus_tag="ACL8CG_001974"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGS1344514.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5976..7262)
                     /locus_tag="ACL8CG_001975"
     CDS             complement(5976..7262)
                     /locus_tag="ACL8CG_001975"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGS1344515.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7493..7729)
                     /gene="comW"
                     /locus_tag="ACL8CG_001976"
     CDS             complement(7493..7729)
                     /gene="comW"
                     /locus_tag="ACL8CG_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGS1344516.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7995..8856
                     /locus_tag="ACL8CG_001977"
                     /pseudo
     CDS             7995..8856
                     /locus_tag="ACL8CG_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8891..>9103)
                     /locus_tag="ACL8CG_001978"
     CDS             complement(8891..>9103)
                     /locus_tag="ACL8CG_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1344517.1"
                     /translation="YIMDNARFHRMGKLELLCEEFGHELLPLPPYSPEYNPIKKTWAH
                     IKKHLKKVLPSCNTFYEALLSCSCFN"
BASE COUNT         2922 a         2164 c         1459 g         2558 t
ORIGIN      
        1 aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg tatacctact
       61 agaattctcc ttagaaagcg tcgattcaag tgctatcact gttcaaaaat gatggtcgct
      121 gaaacttctg atgacgtaca gtcatatttc ttttcttttt attatatcac agttttaaat
      181 ctagctttac tagattcacc gctactatct atttattcgg aaaaaagacg aaaaaacctg
      241 agaatcatct caggcttggt cattaaattt ttttctcaat atcgaaaagt ggagaaagtg
      301 gtcgtttttc atgaatacgt acgatagcat cccctaggag atgagcgatt gaaatctgct
      361 caatcttatc aatcaaacgc tcttctggca gatagatggt atccaaaaca accaatttct
      421 taatagctga tttttggata ttgtccgtag caggaccaga aagaactggg tgcgtacagc
      481 ttgcatagac ttcaacagca ccagcttccg caagagcatc tgccgcatga caaatcgttc
      541 cagcggtatc aatcatatca tcaatcaaga tacaagtctt gccttcaacc ttaccgatga
      601 tgttcataac ttcactagta ttcatcttat caacgctgcg acgtttatca ataatagcga
      661 tagatgtttt caaaaattct gccaacttac gagcacgagt cacccctcca tggtccgggc
      721 tgacaaccac atagtcagaa ccaaccatac cacgacgctc aaaataatct gcaatcagag
      781 gagcacccat caaatgatcc acaggaatat caaagaatcc ttgaatttgc gcagcatgca
      841 agtcgatggt caataaacga tccactccag ctacttcaag catatttgcg acaagttttg
      901 aagtgattgg ctcacgcgct ctcgcctttc tatcctgacg tgcataccca tagtaaggca
      961 tgacaacatt gacagattct gcactcgcac gcttcaaagc atctaccata atcaaaattt
     1021 caagcagatt gtcatttaca ggcgaactag ttgattgtag gataaagacg tgtttcccac
     1081 ggattgattc ttcaatgttg acctgaatct ctccatctga aaattggcga acacttgatt
     1141 tccccaactc tatcccaatc tcctgcgcta cacgttctgc caattcttta ttagaagaaa
     1201 gggcaaacag ctttaaatca gaaaaagaca tgatttcctc cggtatatat gtataacttg
     1261 tgcttttcac aagattttcc atctaccatt gtagcgcttt ttgcactatt tttcaatcaa
     1321 aaataaaaga agggcaccat atttgtaccc ttgcatcatt cttttgaaaa atattctagg
     1381 tcatcaactc attgtgtttc tcaacaaagc aataagcatg ataaaaacca tagagagcaa
     1441 tagccgtaac cactggaatc gctaaaggca actctgtttc caactccaca aaaggagagt
     1501 taaacaagaa gtgagttccc aaggctaaac ctagaaaaat aaggccctgt ttcttgccaa
     1561 ccttctgtcc tttataggct ctgtaaagca agtaaacacc tactacagct agacctgaaa
     1621 aagtccagtg agaggcaatt cctgagatga tacgctctaa aattcgcgaa atagtaaagt
     1681 caaagccctc tggcaaatcc gtacgaatat aaccaatatc ctcaatcatt tggaatccca
     1741 aaccggaagc aattccaagt aaaaacaaag attttaattt tcgcacagga atcaaagcca
     1801 aaacaaaaac aagtggcaat aatttcaagg gttcttctac caaaggagcc acaatagcac
     1861 tttcaaaggc atttaaaaat ggactatctg ggaaaagaac ccccagtaaa tcatgtatat
     1921 aagtattagc aaaactagac aaccagcctg aaaggaacat ccctcccaat aaagacagaa
     1981 tcaaaacctt ctttggcaat tcccattttt tcccaatacg gaagagaaaa taaagagccg
     2041 gaatcatgta aaagagagct agaaagatag aaactcccat tagtccatat tccgcacctg
     2101 acctcgaacc gtccgtatag tagatggttt catactgtaa atcaatacat agcaataaaa
     2161 taaaaataaa taaaatactg cttttcttca tacactttct ttctaaatga agtatttata
     2221 attctacgac tgtcatactt cctgtatcaa cattgtaaat agcaccagag ataatgacat
     2281 cgtctggtat taggggagac tcgataagca gttgcatatc ctcgcgtaca ctctcttcta
     2341 tatcttggaa gggcaagaag tcctggtctg acacatctac acctaattcc tcttttaaat
     2401 actcctgaaa aggttcattt tcaaaggtct gagcaccaca gtctgtatgg tgcaatacca
     2461 caatctctct tgtccccatt tgttgctggg aaataactag cgaacgaatc atgtcttcag
     2521 tcactcgacc acctgcattc cgcaagatat gagcatcccc aagtgccaag cccagagctt
     2581 gcgcaacgtg cagacgagag tccatacagg tcacaatagc tactcttgtt ttgggtttaa
     2641 gtggcagatt taactgccca tgtagggcaa cataagcctg attagcttgc ataaactgtt
     2701 caaaatacga cacgattccc tccttgaaaa tttgatagtc aaatatttct cctatcttat
     2761 catttttaag agaatttgtc acggattatg caaagacctt tttcaaaact tcctgaatcg
     2821 ttgtcacgcc aatgacctga atttccttag gcagagtgat tcctgtcaag gaattcttag
     2881 gtacataaat cttagtaaag cccagtttag cagcttcgtt gatgcgttgc tcaatacgat
     2941 tcacgcgccg aatctctcct gtcaagccca gttctccgac aaaacattcc tgaggattag
     3001 ttggcttgtc tttgtagctc gaagcaatag caactgcaac agccaagtca atcgcaggtt
     3061 catccaattt aacaccacca gcagatttga gataggcatc ctgattttgc aagagaagcc
     3121 ctgcccgttt ttccaaaaca gccataatca agctagcacg gttaaaatca agtcctgtcg
     3181 tagtacgctt ggcatttcca aacatggtcg gtgttaccaa agcctgaacc tccgccaaaa
     3241 tcggacgcgt cccttccatg gttacaacga tggaggaacc agtcgcccca tccaaacgct
     3301 cttctaggaa aacttgactc ggattgagta cctcaaccaa gccgcccgac tgcatctcaa
     3361 aaatcccaat ctcattagtg gaaccaaaac gatttttgac cgctctcaaa atacgaaagg
     3421 tgtggtgacg ctccccttca aagtaaagca ccgtatccac catatgctcc aacatacgag
     3481 gcccagccaa ggttccttct ttggtcacat gacctacgat aaagatggca atgttattgg
     3541 tcttggccaa ctgcatgagt tcagcggtca cttcacgcac ctgagaaaca gacccctgca
     3601 cccctgaaat ctcaggagac atgatggtct ggatggaatc aataatgaga aagtctggct
     3661 ggatacgctc cacttctgca cgaacactct gcatattggt ctctgcatag agataaaact
     3721 cactatcaat atcacctaag cgctctgcac gtagtttaat ctgctgggca gactcctccc
     3781 cactgacata gagaactgtc cccacttggg acaactgggt tgagacttgt aggagaagag
     3841 ttgatttccc aatcccagga tccccaccga taaggacgag acttcctggt accactccgc
     3901 ctccaagcac acggttgaat tcctccatct ccgtcttggt tcgattgaca ttggtggaag
     3961 tcacctcagc tagtttcatg ggcttggttt tctcacctgt caaggacaca cgcgcattct
     4021 taacttcggc aacctcaacc tcttccacaa aagaagacca agacccacag ttggggcaac
     4081 gtcccagata tttaggggaa ttatacccac aattttgaca tacaaatgtc gcttttttct
     4141 ttgcgatgac aaacctcttt ctatatctct aactcacact caatcacttg gcaaaaatca
     4201 atcttctcat ttggcacaaa ctggcgcatg agcattcgat gagcaacaac taccacagtc
     4261 tgatgttctc gatacttaga catacattct agaaaccgag acttcatttc cgtagctgtc
     4321 tcatattgaa taggactatt aggaagcaac tcccccttgt tttctaaaaa cagtcttcta
     4381 gctgtttcaa agttttctat tcctgtttta tagacctgcc attcatgtaa taaaggctct
     4441 actcttaaag gaagacccgt agcacagacc acatacgaag ccgtttctaa agctcttgtg
     4501 actgcagaag atacgattat ttcagctgac gagagtaaag gatttttgct caatttctgg
     4561 acttgctgcc gtcccatctc agacaagggt gccaaatcta tcccaaatcc tatataagaa
     4621 cgctcctcta actcacggta atctggctcc ccatgacgta caaagataat cttcattcta
     4681 gtgccctgtc gatccaaatc caccagttcg aacgccatca gctgcatctc catctgcaat
     4741 taagaaagta gcaaaaacag cctggacaat acgctcccca acttcaagaa caacctcttg
     4801 gtctgtgata ttcttcatct gcgcaaaaat atgcccttca tttccaggat ttccataata
     4861 atccccatca atgaccccaa ctgagttaat taaaaccaag cccttcttac gaggatttga
     4921 agaacgatca tagaggtaga gaacctcagt cggctgcata taagccttaa cccctgtcgg
     4981 aaccaagaca atctctcctg gcgcaacaac tgtacgcaca gcaaccttta agtcgtaacc
     5041 agccgcatgc gctgtctcac gcttgggcaa taaattttca tctgtaaaac tcgaaaccaa
     5101 ttcaaaacca cgaattttca taattttctc ttttctatta tcatttattc tagattattc
     5161 tatcttattt attcggaaaa agcacgaaaa aaagagcaca caattcaaat cgcttagggc
     5221 tgctggattc ctcccctgac ccgcttcacg cagaactgtt gctccactat ttattatatc
     5281 acattcctat tcattttaaa agcaaaatta ttttttccgt ctatttctaa aaaaatcctg
     5341 catgatagct gcgcattcat cttccaaaat tcctatttca acctccacac gatgattgag
     5401 acgctcatct gtcaagatat cgtacaaact cccagcagcg ccaaatttct ggtttttagc
     5461 cccatagacc acatttggaa tgcgggcaag cccaatcgcc ccactacaca tgacacaagg
     5521 ttcaatggtc acaaaaagtg tgcaatccag caagcgccag ctctcctcac tcaagttcgc
     5581 atcctctata gccataattt ccgcatgcat aaccgctcgc tgtaattcct cacgcgcatt
     5641 atgcccacga ccaatgattt ccccatcttt gacaatcaca caaccaattg gaatttcatc
     5701 gtgttcaaga gcaatctcag cctctctcaa agcctccctc ataaagactt ctttttcttc
     5761 aagcgtataa tacatctctt ttctcttttc ctacttatcg attttattat tatatcatga
     5821 atcccaacac aaaaaaagcc accgaatgcg gtgactctat agggagatta ttatgaaaaa
     5881 gaaaagttta ggatatttgt tacaacaagt taggaggtct tcttgtaacc gtctatagta
     5941 tacccgacct atcttaaaca aatcttaaaa atctcttagg accaaacact ttctaaaata
     6001 tttgtttgtt cacgaccagg acctactgag aaagtagaaa tacgaacgcc aaccaattca
     6061 ctcacacgac gaacatagtt acgcgcattc tcaggaagat cttccaaatt gcgaactccg
     6121 gtaatatctt ctgaccaacc tggtaactct tcatagatag gcttgcaacg tttcaattgc
     6181 tcaagactag ctggatagta gtcaatacgt tgaccgtcaa gatcataggc cacacagatt
     6241 ttcacagtat ccaaaccgct caaaacatca atagagttca aagaaaggtt agtaatacca
     6301 gaaacacgac ggctatgacg catcacaact gagtcaaacc aacctacacg acgtggacga
     6361 ccagttgttg taccatactc atgacccact tcacggatac gttctcccac ttcatcaaac
     6421 aactcagttg ggaaaggacc atctcctaca cgactcgtat aagctttaca tacacctaca
     6481 accttgtcaa tcttgcttgg accgacacca gaaccaattg tcacaccacc agctacaggg
     6541 tttgatgacg taacaaatgg ataagtacct tggtcgatat ctagcataac accttgtgca
     6601 ccttcaaaaa gcacacgttt gccattatca agcgcatcat tcaagataac agatgtatct
     6661 atcacgtatt tcttgatttg ttgaccatat tcgtaatatt cttcaaaaat atcatcgaaa
     6721 acaatcgctt tactgtcata caatttttca aaaagacgat tcttttcagc aaggttacgt
     6781 tctaaacgct cacggaaaat atctttatct aaaagatctg caatacgaat tccaacacga
     6841 gcagccttgt ccatataagc tggaccaatt cccttaattg tcgtaccaat cttattgtcg
     6901 cccttagctt cttcttgcaa gcgatccaac tcgatatgat aaggcaaaat aacatgcgca
     6961 cgatcagaaa tacgcaagtt atcagttgtt acaccttcct catgaagata gctcaactct
     7021 tttacaagag atttaggatt tacaaccata ccattcccaa tgacagatat tttttcaggg
     7081 aagaaaatcc cagatggaat caagtgcaac ttaaatttct taccgtcaat cacaatcgtg
     7141 tgaccagcat tatcaccacc ttggtaacgt gcaatcactt ctgcattcgc tgaaaggaag
     7201 tctgtaatct tccctttacc ttcatcaccc cattgggtac ctacaacaac aactgaagtc
     7261 ataattttgt ctgagccctc aggctcttcc tttctcacat acatggcagg actctcacct
     7321 gcaattatat cttacaattt attataataa aaaatcgcct ttttatcaag aagaaacaat
     7381 agaaagattt gctatttcca actattaaaa aatgatttag aaaaattact agctatttac
     7441 tattatcttt ccataaaaga gtaaattagt tcggaaattt actaaaatta cctcaacaag
     7501 aaataaaacc ccgattcatt accaattttt caagatacaa acgataagca acacgataat
     7561 ggtaaacaat aaaatcctta cgacaaccaa tgccatatct cactaaataa taaattaaaa
     7621 atttaaaatg aacatgttcc cagtcaaaat tatcaccaaa tgtaggacca tactcttctt
     7681 caatactatc atagaaatta gccatctgct cataaatttt ttgtaacata atcaaatact
     7741 ccttttcttt tttataaact tattctaaca aaaaatttta cacattcact atcaattcct
     7801 gaattgttaa aataccagcc tcaacaagat aaaaatagga aaagttgaca aaatagaaac
     7861 aaatttgcta cctaaatttc aaacaattaa agttctaaaa agaccgcctt aaaacttttg
     7921 ggtaaatcct attagaacta taatattttt atataggtat tatggttctg attttctagt
     7981 ataaaaaaat tcaaactaga attcttctta gaaaaggccg ttttaagtgc tatcattgct
     8041 caaaaatgga gctcgctgag acttctatcg tcaagaagaa tcatcaaatt ccttgtatca
     8101 tcaaccaaaa gattgctcag aagctaattg aaaagacttc tatgaccgac attgatcatc
     8161 agttgtctat ttcaacttca actgtcattc gcaagatcaa tgattttcac tttgagcatg
     8221 atttttcgcg tcttcctgag attatgtcct agtacgttga aacagtccag ggagtgacta
     8281 tttcaatcgg gagatggaga tgagctttat tgctcaggac tttgataagc tcaatatcat
     8341 aactgttctt gagagcagaa cacaagccat catccgaaat cccatggata caaggctatc
     8401 aagcgctact ggaaactcat tcaacaggat agtcgtaaac tgagtgataa acatttttat
     8461 cgtcctactt ttcgtatgca cttaaccaat aaagagattt taaacaagct tttgagttat
     8521 tcggaagact tgaaacacca ctatcaactc tatcagctct tgctttttca cttccagaat
     8581 aaggaaccag agaaattttt cggacttatt gaggacaatc ttaagcaggt tcatcctatt
     8641 tttcagactg tctttaaaac cttcctcaaa gataaagaaa agattgtcaa cgcccttcaa
     8701 ttaccttatt ccaacgccaa actggaagcc accaataatc tcatcaaact tatcaagcac
     8761 aatgcctttg gttttaggaa ctttgaaaac ttcaaaaaag aaaggacgaa atttgtcctt
     8821 tctaaatctt cgctttcttc aacccactac agttgacaaa gaaccgaaaa atgtctcgcc
     8881 tctaatatag tcaattgaaa caagaacaag acaaaagagc ctcgtaaaag gtattgcaac
     8941 ttggtaatac ctttttgagg tgctttttga tatgagccca tgttttctta ataggattgt
     9001 actcaggtga gtagggagga agaggtaaaa gttcatgccc aaactcctcg cataaaagtt
     9061 ctagcttacc cattctatgg aatcttgcat tgtccataat ata
//
LOCUS       DBEROT010000061         8968 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.61, whole genome shotgun sequence.
ACCESSION   DBEROT010000061 DBEROT010000000
VERSION     DBEROT010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8968
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.61"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            120..275
                     /locus_tag="ACL8CG_001979"
                     /pseudo
     CDS             120..275
                     /locus_tag="ACL8CG_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            475..3750
                     /gene="rexB"
                     /locus_tag="ACL8CG_001980"
     CDS             475..3750
                     /gene="rexB"
                     /locus_tag="ACL8CG_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGS1344518.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDAHSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGSIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3747..7397
                     /gene="addA"
                     /locus_tag="ACL8CG_001981"
     CDS             3747..7397
                     /gene="addA"
                     /locus_tag="ACL8CG_001981"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGS1344519.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFVGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTGTKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7612..8790
                     /locus_tag="ACL8CG_001982"
     CDS             7612..8790
                     /locus_tag="ACL8CG_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344520.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDCQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         2791 a         1861 c         1894 g         2422 t
ORIGIN      
        1 gattgaaata agatacgaac agcttgatta gggaaatcaa attaatttct agaaatattt
       61 tagcatccac gatgtactat tatagtttca atttactata gttcaatcat tctatcaaga
      121 atattgaata tataaaggca cgtaatatta aaacttcttc tgatatcgaa ttagagtccg
      181 atgttgatgg cgataaatca gacaatctac ccgtcgacat taagatactg ggacaacaca
      241 ttgaagtgta ttccgtacct aagaaacaat cataaaactc aaagtcttgc taccgaggct
      301 tttttattat gtgattttca gtagccagac ttattctatc taatacaagt aaagctaagt
      361 atttaagatt tagcagatga tgaagaaaag aaaggatggc ctaaatattt taacagattt
      421 acgaggctaa tcatggtata atatagggtg atgaaaaatt ccaacgaggc tgagatgaaa
      481 ttactttata ctgatattcg aacttctttg acagaaattc taacaagaga ggcagaagag
      541 ctagttgcag ctggcaagcg ggtcttctac attgccccca actctctttc ttttgaaaag
      601 gaacgcgccg tgctggaatg cttgtcccag caggcttctt tttcgattac cgtcacgcgc
      661 tttgctcaaa tggctcgtta tctggtcttg aatgatttac cagttaaaac tactcttgat
      721 gatatcggtc ttgggttggc cttttacaaa tgccttgccg aactcgatcc caaggacttg
      781 cgtgtttatg gagctattaa gcaggatcct caattgatcc agcagttaat tgagctttac
      841 catgagatga ccaaatctca gatgagtttt ttggacttgg agaatttaac agatgaggat
      901 aagaggacgg atttactctt gatttttgag aaagtaacag cctatcttaa tcaaggtcag
      961 ttagcccagg gaagtcagtt gtcccatttg attgaggcta ttgagaatga caaggtaagt
     1021 agtgatttta atcaaatcac cttggtcatt gacggcttta ctcgtttttc tgctgaggaa
     1081 gagcgggttg tggacttact tcacggcaaa ggtgttgaga ttgttatcgg ggcttatgct
     1141 agtaagaaag cctataccag tccttttagc gagggcaatc tctaccaagc cagcgtaaaa
     1201 tttctccatc atctggcttc taaataccaa acgcctgctc aggactgttc tcaaactcat
     1261 gagaagatgg atagttttga caaggcctct cgtttgttgg agtcttctta tgacttttca
     1321 gaactcgctt tggatgtcga tgagaaagac cgtgaaaatt tacaaatctg gtcttgtttg
     1381 acgcaaaagg aggagttgga gctagtagcc cgtagcattc gtcagaaatt acatgagaac
     1441 tcagacctga gctacaagca ttttcgtatt ctcttggggg atgtagcttc ttaccagtta
     1501 tctctcaaaa ccatttttga ccagtatcag attccttttt atcttggtag aagcgaagcc
     1561 atggctcatc atcccttgac tcagtttgtc gagtctattt tagctttaaa acgttaccgt
     1621 tttcgtcagg aggatttgat taatcttctt agaactgatt tgtatactga cctcagtcag
     1681 tctgatattg atgcttttga gcaatatatc cgctatcttg gtatcaatgg cttgccagcc
     1741 tttcagcaaa ccttcaccaa atcccaccat ggaaaattta atcttgagcg tttgaatgtc
     1801 ctccgcctga gaattttagc acctcttgaa accctctttg ccagccgaaa acaaaaggct
     1861 gaaaaactcc tacaaaaatg gagtgtcttt ctaaaagaag gagctgtgac caagcagtta
     1921 caagatttga caaccacttt ggaagctgta gaacaggaaa gacaagccga agtttggaag
     1981 gctttctgcc atgttttaga acaatttgcg actgtttttg ctggttcaca ggttagtctg
     2041 gaagacttcc tagccttgct ccattctgga atgagtttgt cccaataccg taccattcca
     2101 gcaacagtgg acactgttct ggtgcagagt tacgatttga ttgcaccatt gactgctgac
     2161 tttgtctatg ctattggact aactcaggac aatttaccaa aaatttctca aaacaccagt
     2221 cttctgacag atgaagaaag gcaaaaccta aaccaagcga ccgaagaagg cgttcaatta
     2281 ctgattgcca gcagtgaaaa tctcaagaaa aatcgctaca ctatgctttc cttggtcaat
     2341 tctgctcgta agcagttgtt cttgtcggct ccaagccttt ttaacgaaag tgaaagtaag
     2401 gaatctgcct atcttcaaga gttgatccat tttggattta ggcggagaga gaagaggatg
     2461 aatcacaaag gactgtctaa ggaggatatg gggtcctatc acagtctttt gtctagtctg
     2521 gttgcctatc accagcaggg tgagatgagc gatactgagc aagatttgac ttttgtcaag
     2581 gttctgtcgc gtgtcatagg taaaaaacta gatctgcaag gtctggaaaa tccagccatc
     2641 ccaaccagtc caagcagcaa gaccttagcc aaggacacct tgcaagctct ctatcctgcc
     2701 aaacaggagt tttacctgtc tacgtcgggt ttgacagagt tttatcgcaa tgaatacagt
     2761 tatttcctac gctacgtttt aggcttgcag gaggaattac gtttgcgtcc tgatgcccat
     2821 agtcacggga atttcttgca tcgtatcttt gaacgcgcct tacagttgcc taatgaagat
     2881 tcctttgacc aacgtctaga acaagctatt caagaaacca gtcaagaacg cgaatttgaa
     2941 gctatttatc aagaaagttt ggaagcccag tttaccaagg aagttttgct tgatgttgca
     3001 cggacgactg gacatattct ccgacacaat ccagccatcg aaaccatcaa agaagaagca
     3061 aattttggtg gaaaagacca agcctttatt caattagaca atggacgcag tgtctttgta
     3121 cgaggcaagg tggaccggat tgaccgtttg aaagctaatg gatcgatagg agtagtagac
     3181 tacaaatcca gtctgactca gttccagttt cctcatttct ttaatgggct caattctcag
     3241 ttaccaacct atcttgctgc cctaaaaaga gaaggggagc agaacttttt cggcgccatg
     3301 tacttggaaa tggctgaacc tgtccaatct ctgatggcgg taaaaagtct ggcaggagca
     3361 gtggtagaag ccagcaaatc tatgaaatac caagggctct tcttggaaaa agaaagcagt
     3421 tatttaggcg aattttataa caaaaacaag gctaatcaac tgacagatga ggaatttcag
     3481 ctcctactgg actacaatgc ctatctttac aagaaagctg ctgagaagat tttagcaggc
     3541 cggttcgcca tcaatcctta tactgaaaat ggcagaagca ttgccccata cgtccagcaa
     3601 catcaggcta ttacaggctt tgaagccaat taccatctgg gccaagcccg tttcctagaa
     3661 aaattggacc tagctgatgg caagcgtctg gtcggagaaa aactcaagca agcttggttt
     3721 gaaaaaataa gagaggagtt aaatcgatga agcttattcc ctttttaagt gaggaggaga
     3781 ttcaaaaact gcaagaagca gaagcaaatt cgagcaagga acagaagaaa actgccgaac
     3841 aaatcgaagc tatctacact tctggtcaga atatcctggt ctcagcatcg gctggttctg
     3901 gaaagacctt tgtcatggta gagcgcattc tggaccaatt ggcgcgtggt gtcgaaattt
     3961 ctcaactctt tatctcaacc tttaccgtca aggctgcaac tgaacttaaa gaacgtttag
     4021 agaaaaaaat cagcaagaaa atccaagaaa cagatgatgt cgatctcaaa caacacttgg
     4081 gtcgccagtt ggcagaccta cccaacgctg ccatcggaac catggactct ttcacacaaa
     4141 aattccttgg caaacatggt tatctgcttg atattgcacc taatttccgt attttacaaa
     4201 accaaagcga gcaacttctt ctcgaaaacg aagtctttca tgaggtcttt gaagcgcatt
     4261 accaaggtaa acagaaagag agctttagtc atttgctgaa aaactttgtt gggcgtggca
     4321 aggacgaacg gggtctgcgg cagcaagtct ataaaatcta tgacttcctc caatccacca
     4381 gtaatcctca aaagtggctg agtgaatctt tcctcaaagg ctttgagaaa gctgatttta
     4441 ccagtgaaaa agaaaaactg actgagcaaa tcaaacaagc cctctgggat ttggaaagct
     4501 ttttccgtta ccatctggat aacgatgcca aggagtttgc aaaggctgcc tatttagaaa
     4561 atgttcagtt aattctggat gaaattggct ccctaaatca ggagttcgat agtcaggctt
     4621 atcaggcagt acttgcgcgt gttgtcgcca tctctaagga gaaaaacggt cgtgctctga
     4681 ctaatgccag ccgtaaggct gatttgaagc ccctggctga tgcctacaac gaagagagaa
     4741 agacccagtt tactaaacta ggacaattat cagaccagat agcgattctc gactatcaag
     4801 aacgttatca tggagacact tggaaactag ctaaaacctt ccaatctttc atgagcgatt
     4861 ttgtagaggc ttatcgtcag agaaaacgac aggaaaatgc ctttgaattc gctgatatca
     4921 gccattacac cattgagatt ttagaaaatt tcccacaagt tcgtgagtct tatcaggagc
     4981 gcttccatga agtcatggtc gatgagtatc aggataccaa ccatattcaa gaacggatgc
     5041 tggaattgtt gtctaatggc cacaatcgct ttatggtggg agatatcaag caatccatct
     5101 atcgtttccg tcaggcagat ccgcagattt tcaatgagaa attccaacgc tatgcgcaaa
     5161 atccccaaga aggcaagctc attctcctca aggaaaattt ccgtagtagt tcagaagtgc
     5221 tgtcagcaac caatgatgtc tttgaacgtc tcatggacca agaggtcggc gaaatcaact
     5281 atgataacaa gcaccagctt gtttttgcca ataccaaact gactcccaat ccagacaaca
     5341 aggcagaatt tctcctctac gacaaggacg atacaggtga ggaagaagag agtcaaacag
     5401 gaacgaaact aacaggcgaa atgcgcttag ttatcaagga gattctgaaa cttcatcaag
     5461 aaaaaggtgt tgcctttaag gaaattgccc ttctgacctc cagccgcagt cgtaatgacc
     5521 agattctcct cgccctgtct gagtacggaa ttcctgtcaa aactgacgga gagcaaaaca
     5581 attatctcca atccctagaa gtgcaagtca tgctagacac tcttcgtgtc attcacaatc
     5641 ccctgcaaga ctacgccttg gttgccctta tgaagtctcc aatgtttggt tttgatgagg
     5701 atgagctagc acgtttgtcc cttcagaaag cagaggataa agtccacgaa aatctctatg
     5761 aaaaactggt caatgcacaa aaaatggcaa gtagtcaaaa aggtttgatt cacacagctc
     5821 tagctgaaaa actaaagcaa ttcatggata tcctagcttc ttggcgcttg tatgccaaaa
     5881 cccactctct ctatgacttg atttggaaga tttacaacga ccgtttttat tatgactatg
     5941 ttggggcttt gccgaatggt cctgctaggc aggccaatct ctatgcccta gcactgcgtg
     6001 ctgatcaatt tgaaaagagc aatttcaaag gtttgtcgcg ttttattcgt atgattgacc
     6061 aagtcttaga agcccagcac gatttggcaa gcgtggccgt cgcaccgcca aaagatgcag
     6121 tagagctcat gaccatccac aagagtaagg ggctggagtt tccttacgtc tttatcctca
     6181 atatggatca agatttcaac aagcaagact ctatgtcaga agtcattctc agtcgtcaga
     6241 atggtcttgg tgtcaaatat attgccaaga tggagacagg ggcagtagaa gaccactatc
     6301 ctaaaaccat caaactctcc attcctagcc tgacctatag gcagaatgaa gaggaattac
     6361 agctagcaag ctattctgag cagatgcgtt tgctgtatgt tgctatgacg cgggctgaga
     6421 aaaagctcta tcttgtcggc aagggttctc gtgaaaagct ggaagccaag caatacccag
     6481 cagccaaaaa tgggaaacta aatagcaata ctagactgca agcacggaat ttccaagatt
     6541 ggctttgggc tatcagtaaa gtgtttacta aggacaagct caactttagt tatcgtttta
     6601 ttggcgaaga tcagttgacc agagaagcta tcggagagtt ggaaaccaag agtcctctcc
     6661 aagatagctc ccaagcagac aatcgtcagt cagataccat caaagaagct ctgaaaatgc
     6721 tgaaggaggt ggaagtttat aatactcttc accgcgcagc tattgaactt cctagtgttc
     6781 aaaccccaag tcaaatcaag aaattctacg aaccagttat ggatatggaa ggtgtcgaga
     6841 ttgctggtca aggtcagtca gtaggcaaga aaatcagctt cgatttgcca gatttttcaa
     6901 caaaagaaaa ggtaactgga gctgagattg gtagtgctac tcacgaactc atgcagagaa
     6961 ttgacctcag ccagcaacta acccttgcta gcctaacaga aacactcaaa caagttcaaa
     7021 ctagccaagc tgtcagagac aagatcaatc ttgataaaat tcttgctttc tttgacacag
     7081 tactcggtca ggaaattctt gctaataccg accatctcta tcgcgagcaa cctttctcca
     7141 tgctcaaacg agaccaaaag agtcaggaag actttgttgt ccgtggtatc cttgatggct
     7201 atctgcttta cgaaaacaaa attgttctgt tcgactacaa gacagaccgc tatgatgaac
     7261 caagtcaact cgtagaccgc tatcgtggtc agttagctct atacgaagag gctttatcac
     7321 gagcctattc gattgaaaat attgaaaaat acttgatttt actcggtaaa gacgaggttc
     7381 aagttgtaaa agtataactt atactctttg aaaatctctt caaaccacgt cagcttcgcc
     7441 ttgctgtata tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt
     7501 gagctgactt cgtcagttct atctacaacc tcaaaacagt gttttgagct gactgcgact
     7561 agctttctag tttgctcttt gatttttatt gagtattaga aaggagacct catgacactt
     7621 ccagttagaa aatccctgca cgatgcagtt ttacaggctt cgaaagcgga tacttgggaa
     7681 caagctacca aggaatggaa tgaagtttcc ttgattttta acggtatcgg ccgtagcaat
     7741 tgtgtctgtg gaaatgccat caaatacgct tatgaactct ttaacggtgt cacaggccaa
     7801 cgcctctttc caattggtag cgactgtgtt cgtcattttc atcgattgtc ccttgaccag
     7861 caattggaag aggaagaaaa actgctcaga aaggttgaaa atctaaccag aaaagctcag
     7921 aaaaaggaaa aaatcaaggt caataaaagt gactttgacg agcgacttct aaaatggctc
     7981 tgggaaaaag gtgttttcaa acccaatcgt ggcaatcaat ttgcgcctga gagagactgc
     8041 cagcttttcc tagaagtctt tcagggagga agttggacca aggcggaacc aaagaaaaag
     8101 gctcggatgg aagaagtcct tgaaaagtgt atcaaaccct ttttacttgg gaaatcggat
     8161 gaccaactct accttgtcaa gctaggcaag gagaaaattg actacgaaca agaactccgt
     8221 atccaggcag agaaagaacg caagaagagg gataaaatcg ccaagcaata tgcagacaat
     8281 ctggttctag ccatgggacc cgcagagcgt gcttatcaag attactttgg ctttacagag
     8341 acactgactc aagaagaacg caagtgggaa aaaattcttt ttggtaaaaa tagagcagaa
     8401 cgggctatca aggccaaaca ataccaaaaa gagctggaaa aagaccaacg aattgccagt
     8461 caggatccaa ttgaaagaaa acagaagcag acttggctcc tcaattccta ttttcgtgag
     8521 cttcctgaag aaaaagctcg attttctaga ctcttattag aatatagaaa aagtggtgaa
     8581 gtaccctttt caactgaata cctgtcagat catctcatcg actttttcta taaaatgaaa
     8641 gcctttgaat ttgaaatcgc accagaacaa gtccgagatt ttctaaaaaa aagcctgcag
     8701 gaagaccatc gctcatcagc acaaggaagc tggatagaag gaattctcct caactgcctc
     8761 aaaccatttt tagaacgatt agtgatatga gtaacaccta ccgtgtaaat ttcatggtag
     8821 gtgttattgt acctccaaat aatataaaac aaagtatgaa agtgcatctc aattttaaga
     8881 cttttttgta aattaagagt ataattaagg tatactgcct tttctataga taatagataa
     8941 tacactaata taataaaggt ctttgtaa
//
LOCUS       DBEROT010000062         8240 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.62, whole genome shotgun sequence.
ACCESSION   DBEROT010000062 DBEROT010000000
VERSION     DBEROT010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8240
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.62"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            96..956
                     /locus_tag="ACL8CG_001983"
     CDS             96..956
                     /locus_tag="ACL8CG_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HGS1344521.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLDKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKIIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     IKENYHVQKL"
     gene            940..2001
                     /locus_tag="ACL8CG_001984"
     CDS             940..2001
                     /locus_tag="ACL8CG_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1344522.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNDLKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            2018..3022
                     /locus_tag="ACL8CG_001985"
     CDS             2018..3022
                     /locus_tag="ACL8CG_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344523.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSATQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIKEKVTMYINPRDIMQF
                     "
     gene            3034..4728
                     /locus_tag="ACL8CG_001986"
     CDS             3034..4728
                     /locus_tag="ACL8CG_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344524.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            4730..5431
                     /locus_tag="ACL8CG_001987"
     CDS             4730..5431
                     /locus_tag="ACL8CG_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGS1344525.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAGVIYVEEIR"
     gene            5478..6077
                     /locus_tag="ACL8CG_001988"
     CDS             5478..6077
                     /locus_tag="ACL8CG_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1344526.1"
                     /translation="MNIIFDLGNVLIEWNKEKILSKICKNDLEYNLFNKFVFQSNLWI
                     DLDNGKISLEFLENQLIDEMGHQYQDQIHELVWNWFNYVDLYDEVYELIKQLKKKNFQ
                     IYVLSNTSSIFHILLDSVLSKVSSVLDGYVISCEVKMMKPQKEIYLSLVNKYQLDIKD
                     CIFLDDLEENVEAARTLGIKAFQIKERKEISNILKDLLN"
     gene            6087..8114
                     /locus_tag="ACL8CG_001989"
     CDS             6087..8114
                     /locus_tag="ACL8CG_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1344527.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESGNSSIVPVKDGKQILTNQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESVKHRYG"
BASE COUNT         2882 a         1069 c         1452 g         2837 t
ORIGIN      
        1 attttaaaaa ataatgaaac gttccaactt atctattgac acgttccaag aaatcggata
       61 caatgtaatt aacaataaag ataggagaaa ataatttgaa tccattaaaa gaatgctatg
      121 aaaaaaacgg tatactaatt gcagcacacc gtggtacaaa cggaggaaat atattacaaa
      181 acacatcaaa agcctatttg aattccatac gccataacgc agatatgttt gaggttgatg
      241 taattcgttc aaaagatgga gaattttttg catttcacga tgggcaagaa cctttagtat
      301 ttggtgaaaa aattgatatt agaactttga gttctgaaga gatccaaaga aaggaatgtt
      361 ttaattcact gaatgaaccc atattacaaa agattgaaaa aatttctgat gtattaaaaa
      421 attttgaggg acaatcttta ataaatatag atagaagttg gttttactgg gataccttcc
      481 tagataagtt aaaaacatat ccatctttga atcaagttct tttaaaatca cctgtaaaaa
      541 aagaattatt ggaaatgctt agagactctg gtttgaatgt tatgtatatg ccaattatca
      601 aaacaattga agagttagat tttgttctct catttgaagg aataaataca gtagctgtcg
      661 aacttgtatt ccaagattta gaaaatccaa tcataagtaa gaaaataatt gatgatttac
      721 atgaaaaagg attacttatt tgggttaatg ctttaacctt aagtgattca attattcttt
      781 cggctaagat tgatgatgat acagctattg ctcatgatgg cgaatcttgg gggaaattgg
      841 tttcaatagg atttgatatt attcaaacag attggccatt attactttat caatatctag
      901 ttgaaaaaaa taaaaaaata aaaataaagg agaactatca tgttcaaaaa ctttaaaaag
      961 attgcattca cttcttcact aattttactt gctgcttgct caaacaatgc ttcaaataca
     1021 aatcagtcta ctgatgaagg aagtgttgat aaatctcaag aaattgtaat ctatacaaat
     1081 tcggcttcta atggacgtgc agattggtta caaactaaag catcagagca aggatacaat
     1141 cttcgtttgg tagatatttc aggtggagaa ctagctgacc gtttgattgc agaaaagaat
     1201 aatgctgtgg ctgatatggt aattggatta aataaattag aatttaaccg tattaaagct
     1261 gaaaaacttc ttgtaaaata ctcaccaaaa tgggctgatg aagtagatag ctctttggga
     1321 gattctgaag ggtattattc accaattgta aatcaaccat tagttttgat tggtaataaa
     1381 gatgctaaaa tgccatccga ctggacagat tttactgatt catcttataa aggtaaatat
     1441 ggtatttcaa aattaagtac aggtacatct aagaacatct ttgcaagtat tgtttcgaga
     1501 tataaagatg aaaaaggtga gttaggaata tctgatgaag gttggaaagt tgcaaaagct
     1561 taccttaaaa atgcacacgt ttatgcagaa ggtgaagact atatctcttc aattatggat
     1621 aataataatg atctaaaata tagtatgatg tggggatctg gtgttctaca aaatcaaaaa
     1681 gaacgtgaat ataaattcca agtaatgtca ccaaaagttg gtgttcctta tgtaactgaa
     1741 caagttggga ttttaaatac aagtaagaag caagcattat taaaagaatt tgtagattgg
     1801 tttggctctt cagaacttca aaaagaatgg tctgataaat ttggttcaat tccagctaat
     1861 aaaaaagctc tagagcaagc aaaagatgaa ctcaaacagt ttgctaatag tgttaaacca
     1921 caagaacttg actgggagtt tatcgggaaa aacatcgatt cttggattga aaaagcacag
     1981 cttgaatttg ttgaacagta atagttagga ttaagtgatg attacattta aggatattca
     2041 aattaagtat aatgatttta ttgccatcga taatctcaat ttaacaatca atgagggaga
     2101 gtttttcaca tttttaggac caagtggttg tgggaaatca acaactcttc gtgcactagt
     2161 tggatttttg gagccttcac aggggcaaat actagttgat aatcaagata ttacgaattt
     2221 agatccggaa aaacgcgaaa ttggtattgt gtttcaaagt tatgcattat tcccaacaat
     2281 gactgttttt gataatattg cttttggtct aaaagttaaa aaagtttctc ctgaaattat
     2341 taaagctaaa gttcatgaaa ttgcgaaaaa aattaatatc tcagacgagc aactaaaccg
     2401 aaatatttct gaattatcag ggggacaaca acagcgtgta gctttagcac gtgcattagt
     2461 attagaacca aaaattcttt gtttggatga accgttatca aacctagatg ccaaactacg
     2521 agtttcgttg agaaaagaat tgaaacgatt gcaaaaagaa ctaggaatca ctactcttta
     2581 tgtcacacat gatcaagaag aagcattaac attatcagat aggattgctg tgtttaataa
     2641 tggatttatt gagcaagttg gcacgccgta tgatatttat aatcaatccg caactcaatt
     2701 tgtctgtgat tttattggct caatcaataa aattagccaa gaagttctta aaaaattaca
     2761 aggcgagaat aaatacttta aagaaactga aggatacata cgcttagagc gtgttaagtt
     2821 agagaaaact tcacctcaag atttatctat aacaggggta attagtgata ttgagtttaa
     2881 tggtgtactt attaagtata aagtagactt gtcgaatagt gaaagtattc atattatcga
     2941 aaagaatgat ggactatcac gtcatataat caaagaaaaa gtcactatgt acattaatcc
     3001 gcgtgatata atgcaatttt aaggagattg tgcatgagaa agagtctaaa ctggaaagat
     3061 tgtctcataa gattaggagt tttatggcta atctttgccc tgattattta tccaaatatt
     3121 gaacttttgt ctggagtgtt ttataaaaat ggttcattta ctctagaggc attcaataag
     3181 attatacact ctcagagagc gatgagtagt atatttaata gctttatttt ggcgatttca
     3241 atggtcttta ctgtaaatat tgttgggaca ttgattgttc tactcacaga gtactgggat
     3301 attaggggtt caaaaatact taaattaggt tatatgagct ctctagtata tggaggaatt
     3361 gtattagcga caggatataa atttgtttat ggcgctaatg gtcttgtaac taaaacgctc
     3421 tcaagtataa ttccaggtct tgcccctaac tggtttcaag gatttggtgc agtattgttt
     3481 attatgacat ttgcttgtac ctcaaatcac ataatgtttt taacaaatgc agttcgtagt
     3541 gttgattatc atacaattga ggcagctaaa aatatgggtg caagtccttt aaaagttttc
     3601 tttagtgtgg tttttccaac ttttaaacct acgttatttg ccttaaccat cttaactttt
     3661 ttgacaggtc tttcagcagt ttctgctcct ttgatagtag gggggaaaga ttttcaaact
     3721 attaacccat tgattatcag tttcgctaaa actacaagtt cgagagattt agcagcttta
     3781 ctagctatca tgttaggttt agcaactatt ctattattga cacttttgaa tcatgtcgaa
     3841 aaaggaggta attatgtatc tgtttcgaaa accaaggcta gtattaagaa gcagataatt
     3901 tcttctccat tatggaatac tcttgctcac attgttgcgt atgtattgtt tgcaatctat
     3961 atgttaccaa tagttttgat aattctatac tcgtttacag actcgttgac gatcaagacg
     4021 ggaactttag atctatctaa atttacgtta gcgaactatg ctaatttatt tacagatgct
     4081 caatcatttc gtccttacct agtcagcgtt gtttatgcaa ttttagctgc ggtaattgct
     4141 acaattatag caatagtaat ttcacgtatt gtacataaaa acaagagtaa gttcgataaa
     4201 ttctttgagt atggtgcact gataccatgg atattgccag gtacattgat tgcactagga
     4261 ttaatgttca cttataatat acctcattta atactattta atttagtttt agtaggaaca
     4321 gtaattattt tacttattgc atatactatt caaaaattac cattttctta tagaatgatt
     4381 cgggctgtat ttttcagtat agataatgat atggaagaag ctgcacgtag tatgggtgca
     4441 tctagtttct acactatggt gcgagttatt ataccgtata ttttaccagt cgtattatca
     4501 gtagttgtgt taaactttaa ttctttatta tctgactatg acttatctgt attcttgtac
     4561 catccacttt tccaaccatt gggaatcgtt attaaacagt ctactgatga aacagcaact
     4621 ttaaatgcac aggcaatgat gtttgtttat tctgtaattt taatgattat gtctagtgca
     4681 gctctttatt tatcaagcct attccaaggt aaacgaggta agagataata tgaatctttc
     4741 atacgaactg agtatttggg aaatacttct taggtgcttt ttagcgattc ttttcggtgg
     4801 cattgttggc tatgagcgag gagtcaaaaa ccaagcagca gggattagaa cctacttact
     4861 agtttgtttg ggaacttgtg ttgtaatgat gacaaatcag ttcatcacta gtcgttatgg
     4921 tagcggtgat cctagtcgaa tgggagccca agtaattagt ggcttgggtt tcctaggggc
     4981 aggaacaatc atggtaacta atcaaaaagt taaaggttta acaacagcag ctggattatg
     5041 gtcttcagca actattggtt tagctatagg cattggtttt tatgaaggtg ctattttagc
     5101 cggagttgta ctcatagcag ttttaactct atttactcct cttaaagatt atttaaactc
     5161 gaaaactaaa attgctgatt actacttggt ttttagttct ttagaaggtt ataatcgttt
     5221 acttatatat ttaaatacat cgggtattaa gattttagaa attcaaaatg gtataggaaa
     5281 tcttgatgaa gaacgtcaat taaataaaat taagtcaaca aaagtgtcct gctatttatc
     5341 attaaaatta aacgaaaact ttgaacattt aaaattaatg gaagaaatgc ataatattgc
     5401 tggtgttatt tatgttgaag agattaggta agggtgactt tgtctaattt tttctatatt
     5461 tctaatcgga gaaaaaaatg aatataattt ttgatttagg gaatgtgttg attgaatgga
     5521 ataaagaaaa aattttatca aaaatctgta agaatgattt agaatataat ttatttaata
     5581 agtttgtatt tcaatctaac ttgtggattg atttggataa tggtaaaatt agtttagagt
     5641 tcttagagaa tcaattaatc gatgaaatgg gacatcaata tcaggatcaa attcatgagt
     5701 tagtatggaa ttggtttaac tatgttgatt tatatgatga agtttatgaa ttaataaaac
     5761 agctaaagaa aaagaatttt caaatttatg ttttatcaaa tacctcctca atttttcata
     5821 ttttattaga ttctgttcta tctaaagtat catctgtttt agatggttac gtaatttctt
     5881 gtgaagttaa aatgatgaaa ccacaaaaag aaatttactt gtcattagtt aataaatatc
     5941 aattagatat aaaagattgt atatttttag atgatttaga agaaaatgta gaagctgcaa
     6001 gaactctagg tattaaagca tttcaaatta aagagcgtaa agagatctca aatatactaa
     6061 aagatctctt aaactagagg ttaattatgg ttacaataaa agatattgca agagtgtctg
     6121 gagtctcaca tgggacagtt tcaaacgttt taaataaaaa aggtaatgtc tcagcagcta
     6181 aaataaagtt agtagaagag actgcgaaaa aattgggtta taatatgaat tctcaagctc
     6241 agtttcttcg aaaaggcgct tctagtaaat gttttttctt gttatttaat aatgcacgca
     6301 aaaagtatgc tgagtatttt gcagaaattg atcagttatc tttagatgta gaatatgttt
     6361 acttacataa attctcagag attaaaaata agatatctgc aattttaagt gaaaatcctc
     6421 aatttatagt ttgcttaggt ttttctccaa aaagattcgt tgatattgaa gataatattc
     6481 cgatttttga agtagataca tatcaatcta ataaaacttt atcttccttt gatagtgata
     6541 aaatatttga gattgtactt gagttggttc ggactgaaaa gctatctaat ttatatttta
     6601 tttcacttac taatgaaaaa gaacattctt tatttgaata tttgactcaa aaaataaaaa
     6661 actcaactca tatacaagtg caagaacgtt tacaattgtt gtctctatat cctactctaa
     6721 aaaactttgc aaagtatgat tgtatatttg ttgatgatga agatttgatg cacacgctat
     6781 tagacttatt tgattggttt actataattg atagaccaaa aatatgtttg ataggttcac
     6841 gtgtttggtt cgaaaaaaga aatctttttt atatacattt agattataga atattggcac
     6901 tcaatactgc cgaaaattta gaaagtggaa atagttcaat tgtaccagtt aaagatggca
     6961 aacaaatttt aactaatcaa ttatttgatg gagaatgtga tgatatttat ttacttactg
     7021 tccattcacc aatgaataaa gccttagaaa ttttatcaga aaagtataaa caaatttctg
     7081 ggaaaaatat taaaattatc gagaaaagat atgatgaact tttggagatg attgagtctg
     7141 gcgatgtttc atccagtttt gatatgatta gaatggatat ggcttggctt ccaacatttg
     7201 ggaaaaagta ttttcaagag attacaagct ttagacaaac aaaaagtatt aatcaaaata
     7261 tttctaagtc ggtgtctcga gagtatatgt atattgatca gaagcaatat acttttccat
     7321 tggatgttag tagtcagatt ttagtatata gaaaagactt atttgaagat tcatttttac
     7381 aaagacgata ctttgaaaaa acaaaaagaa aattaactgt accaaaaagt tatcaagagt
     7441 ttgatgagtt aagtgaattt tttacattaa cagaaaatcc attttcacct acactttatg
     7501 gccatagttt agctttaagt tcttcagtga gagcagcatg tgaatttatt cctcggtttc
     7561 gtgagagatt agcacaatct agaatgaatc ttgctgtact tcctcaggtt ttaactgagt
     7621 atgagaaaag ttatcagttt accgaaaaat catttaattc ttcgtggaac gatttcgtta
     7681 cgaacttaaa cagtggtaaa acttcaatgg aaataatttt ttcaaattat actagtccat
     7741 tatttgatgg tctcaatgtt tctgctcagt ttgagtttgc aactgccact atacctggta
     7801 atactcctgt gataggtggt ggctcaattg gaatttctaa atattcaaat agagtggaag
     7861 aatgtctaaa ctttattaat tggttatatt ctgaagagat ttctatttta ctaacatctc
     7921 tgggtggttt tttaccatca aagtatgtca tgcaaaatag gatgttacaa tttcaatacc
     7981 catggttatc tagtttagaa gatacattta gtattgggag tagaacaaaa tggtacggct
     8041 ttaatactga ttttagattt gagcagatgt tagggcaaga gttaatagaa agtgtgaagc
     8101 atagatatgg ataaattaat actaaatttt tattactagt ttatttatta ttgtttaaaa
     8161 ttaaagattc aagtaaacac caattatatt taaaattatt attttgacat ttttctattg
     8221 caaagttatt ttattagact
//
LOCUS       DBEROT010000063         8140 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.63, whole genome shotgun sequence.
ACCESSION   DBEROT010000063 DBEROT010000000
VERSION     DBEROT010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.63"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..208
                     /locus_tag="ACL8CG_001990"
     CDS             <1..208
                     /locus_tag="ACL8CG_001990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HGS1344528.1"
                     /translation="LYYRLPIFAKLSEKKLEYMMLGDCVMLVNEMEITDHRVDNLFEK
                     GKNEIKDSSSRFSNRTYKSFRKSI"
     gene            159..467
                     /locus_tag="ACL8CG_001991"
                     /pseudo
     CDS             159..467
                     /locus_tag="ACL8CG_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            631..1290
                     /locus_tag="ACL8CG_001992"
     CDS             631..1290
                     /locus_tag="ACL8CG_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGS1344529.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1315..2382
                     /locus_tag="ACL8CG_001993"
     CDS             1315..2382
                     /locus_tag="ACL8CG_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1344530.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            2486..3496
                     /locus_tag="ACL8CG_001994"
     CDS             2486..3496
                     /locus_tag="ACL8CG_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344531.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFIIPSDVL
                     QF"
     gene            3508..5199
                     /locus_tag="ACL8CG_001995"
     CDS             3508..5199
                     /locus_tag="ACL8CG_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344532.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5202..5912
                     /locus_tag="ACL8CG_001996"
     CDS             5202..5912
                     /locus_tag="ACL8CG_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGS1344533.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6008..6376
                     /locus_tag="ACL8CG_001997"
     CDS             6008..6376
                     /locus_tag="ACL8CG_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344534.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYSSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            6484..7485
                     /locus_tag="ACL8CG_001998"
     CDS             6484..7485
                     /locus_tag="ACL8CG_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1344535.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    7697..7926
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         2740 a         1094 c         1551 g         2755 t
ORIGIN      
        1 actatattat cgcttaccaa tatttgctaa actttcagaa aaaaagttgg agtatatgat
       61 gctaggtgac tgcgtcatgt tagtaaacga aatggaaata actgatcata gagtagataa
      121 cttatttgaa aaagggaaaa atgagataaa agattcaagt agtagattta gcaataggac
      181 atataaaagc tttagaaaaa gtatctgaaa aaacagatgt ttatatctat aacctaggct
      241 cgggagaagg cactagtgta ttacaacttg taaatacatt tgaaagtgtt aataagatcc
      301 ctattcctta taaaatagtt ccaagacgtt caggagacgt tgcaacttat tatgcaaatg
      361 cagacaaagc atataaggaa ttaaattgga ggacaacaaa atcgattgaa gacatgtgta
      421 gagatacatg gaattggcaa tcaaaaaatc ccaatggcta taattgatga tactgtctat
      481 atgagtgctg tattttggaa aaattactta accttttaat gaaagataaa ttaaaaaaaa
      541 tgtttgacag cgcttgacaa aggaaacggt ttcattgtat aatgtaaaca caatgacacc
      601 gatgtcaaat ataaaaaaga aggtctttat atgaaaaact taacaaaaat taagttcaaa
      661 gaaaatgggg aatttaatca tttccctggg aatacagttg tagcaaatct ttatactaaa
      721 caagatttga tggaagttgt tgatattatt caatcacgtt atagagaatt accatttatc
      781 gataagttta ctttaactcc aaggaattct attcacatga ctgtaattga attgttgtgc
      841 catgaaaatc gtgaaacgga gttttggagc agtaatcttc ctctagatac acctttacag
      901 gaaatacatg attactttgc taaacaactt gaaatttttc cattgttgga tgaagaaatt
      961 catatgcgta taactgaaat gggaaaacaa aacatactag ttgaacctgc agatgaagct
     1021 tctgcaaaga gattagaaga aattcgtact tatgtctcag aaaaagcagg tgtttgtttc
     1081 cctaatcatg atagatatca attccatatt tcaattgggt atcttcggat tcctctaacc
     1141 gaagaggagg aagaagagtt tactaaagtc agagcagaat taactgaaat tttattagag
     1201 aagattccaa ctattactgt aaaccgtatt gactatactg tatttgaaga tatgagacaa
     1261 tttgttccat atcacgaaaa atttaaataa aataataaaa aaggagaact tatcatgaaa
     1321 aaaatgaaag tttggtctac tgtacttgca acgggagttg ctcttactac acttgctgct
     1381 tgctctggag gttcaaattc tacgactgct tcttcatctg aagaaaaagc tgataaaagt
     1441 caagaattag ttatctattc gaactcagtc tcaaatggtc gtggtgattg gttaactgct
     1501 aaagcaaaag aagctggttt taatataaaa atggttgata tcgctggcgc tcaattagca
     1561 gaccgtgtta ttgctgagaa gaataatgca gttgcagata tggtatttgg aattggtgct
     1621 gttgattcaa ataaaattag agatcaaaaa ttactagtac agtacaagcc taaatggtta
     1681 gataaaattg atcaatcttt atcagataaa gataattatt ataatcctgt gattgttcaa
     1741 ccattagttt taattggggc gcctgatgta aaagaaatgc ctaaagattg gactgaatta
     1801 ggtagtaagt ataaaggtaa atattcaatt tatggtcttc aaggtggtac aggacgggca
     1861 attctagcaa gtatcttagt tcgttacctt gatgaaaaag gagatttagg cgtatcagaa
     1921 aaaggatggg aagttgcaaa agaatacttt gcaaatgcct atactcttca aaaaggtgaa
     1981 agctcagttg ttaaagcgtt agataaagaa agcccaattc aatacggtat gatctggggt
     2041 tctggagcgt taattggaca aaaagaacaa aatgttgaat tcaaagttat gactcctgag
     2101 attggtgtac catttgtaac tgaacaaact atggttttaa gcactagtaa aaaacaagcg
     2161 ttagctaaag aatttattga ttggtttggt caatcagaaa ttcaagtaga atatagtaaa
     2221 aaatttggat ctattcctgc caataaagat gccctaaaag agttacctga agatacgaaa
     2281 aaatttgttg atcaagtgaa accacaaaat attgactggg aagctgttgg aaagcatttg
     2341 gatgaatggg tagaaaaagc tgaattagaa tacgtaaaat aagaaataag agttattttt
     2401 tatgtccaag tctctctatt atttctaaat ttaaggaaga aataaagaga ggcttttggt
     2461 tttagtaata gagggagtta gtgagatgat taaatttgat aatattcaaa ttaaatatgg
     2521 tgattttgtt gcaattgata atctgaattt agatatacat gaaggggaat tctttacatt
     2581 tcttgggcct tcaggatgtg gtaaatcaac tactttgaga gcattggtag gttttttaga
     2641 tccatcatca ggaagtattg aagttaatgg aacagatgtc actcatttgg aacctgaaaa
     2701 gcgtggaatt ggtattgtat ttcaatctta tgcgctattt ccaactatga ctgtttttga
     2761 taatattgca tttggtttaa aagttaagaa ggtagctcca gatgttatta aagctaaagt
     2821 atcagcagtg gcagcaaaaa ttaagatctc tgatcaacag ttacagcgta atgtatcaga
     2881 attatctggg ggtcaacaac aaagggtagc attggctcgt gctctggttc ttgaacctaa
     2941 aattctttgt ctagatgaac cattgtcaaa ccttgacgca aaattacgtg tagatttgag
     3001 aaaagagttg aaaagacttc aaaaagagtt aggtattact actttatatg ttactcatga
     3061 tcaagaggaa gccttgactt tatctgatag aattgcagtc tttaacaatg gatacatcga
     3121 acaggtcggt acaccagtag agatttatca taattctcaa actgaatttg tatgtgattt
     3181 tattggagat attaatgttt tgaccgatga aacagtccac gaagtattat tgaaaaatac
     3241 aagcgttttc ttagaggata aaaaaggata cattcgatta gagaaagttc gattcaatcg
     3301 tgaaactgaa caagatttta ttctaaaagg gacaattatt gatgttgagt tttctggagt
     3361 tacaattcac tatacaataa aagtttctga aagtcagatt cttaatgtaa caagtattga
     3421 tagtcaggct gctattagat ctgtcggaga aagtgtggaa ttatttatca taccatcaga
     3481 cgttctgcaa ttttaaggag gtgcagtatg cgtcataaat taaatttaaa agattggctt
     3541 attcgtttag ggttaatctg gttcttagta acatttatta tttatccaaa ctttgatcta
     3601 gtagtgaatg tatttgtaaa aggaggagaa ttttcccttg atgctgtaca tcgtgttcta
     3661 aaatctcaga gggcacttca gagtattatg aacagtttta agttagcatt ttcactcatt
     3721 attacagtta atgtcgtagg tattctttgt gttctattta cagagtactt tgatattaaa
     3781 ggtgctaaaa ttttaaaatt aggttatatg acctctttaa tttatggagg agtggtttta
     3841 gcgactggat ataaatttgt ctatggtcct tatggattga ttacaaaatt tttacaaaat
     3901 gttatccctt ctttagactc taactggttt attgggtatg gtgcagtctt attcattatg
     3961 acattttcag gaactgctaa tcatacattg tttttaacaa atacaattcg aagcgttgac
     4021 tatcacacta ttgaggctgc tcgaaatatg ggagcaaaac catttactgt tttccgaaaa
     4081 gtagtgttac caaccttaat tccaactcta tttgcactta ctattatggt ttttcttagt
     4141 ggtttatctg cagtagcagc acccatgatt gttggtggta aagaatttca aactataaat
     4201 ccaatgatta ttacatttgc agggatgggg aattctcgtg atttagctgc cttacttgca
     4261 attattttag gtattgcaac tacaattttg cttactatca tgaataagat agaaaaaggt
     4321 ggaaattata tttctatctc taagactaaa gcgcctctta aaaaacaaaa aattgcgtct
     4381 aagccttgga atatcattgc tcacattgta gcatatggat tgttcacagt tttcatgctt
     4441 ccactaattt ttatagtatt atactcattt acagatccag ttgcaattca aacaggtaac
     4501 ttaacattat caaactttac tttagaaaat tatcgcttat tctttagtaa tagtgcggca
     4561 ttctctccat tcttggtcag ctttatttat tctattattg ctgcgacaac agcaacaatt
     4621 ctcgcagttg tatttgctcg tgttgtcaga aaacataaat ctcgttttga tttcttattt
     4681 gaatatggtg ctctacttcc ttggttacta ccaagtacac ttttagcagt aagtttatta
     4741 tttactttta atcagccaca atttcttgtt ttgaatcaga ttttggtagg tagtttggta
     4801 attctactta ttgcatatat agttgtaaaa atcccatttt cttatagaat ggtacgtgct
     4861 attttattta gtgttgatga tgagatggaa gatgcagcaa gaagtatggg tgcttcacct
     4921 ttttatacta tgatgaaggt tatcattcca tttattttac cggttgttct ctctgttatt
     4981 gctttaaact ttaactcttt attaactgac ttcgacttat ctgtattcct ttaccatccc
     5041 ctagctcaac cattaggtat tacgattcga tctgcaggtg atgaaacagc aacatctaat
     5101 gcacaagctc tggtatttgt ttatacaatt gttctgatga ttatttctgg aacggtatta
     5161 tacttcacac aaagaccggg gcgtaaagta aggaaataat catgacagcc actagtcttg
     5221 ggttatcaaa tattgaaata gttgtcagga ttgttttatc agtagtcatt ggtagtataa
     5281 ttggtttaga gagagggagc aaatcccagc ctgcaggcat ccgaacttat agtattgttt
     5341 gtctagctgc atgtttgatt atgatgacga atgaatacgt atcttataaa tttgggacag
     5401 gagatcctac acgattagga gctcaagtta tatcaggtgt gggttttcta ggcgctggaa
     5461 cgattcttat tacagataaa aagaaaatta caggtctgac aactgcagca ggcatttggg
     5521 cttcggcagg aattggatta gctattggag taggttttta tgagggagct cttttagtag
     5581 ccatttctgt ttggggtgtg atatccatgt tccaaccact aaaaaaatat ctgcaaaatc
     5641 gttctaaaat gattgaattg tatatagtgg ttaaatctac agaagcctat aatcgtgtat
     5701 tggtttattg tgcagaaaat ggtatcagaa tgaccgattc aagaacagcg tttggagatg
     5761 ttaattctga cagaattgaa tactttgatg ttccggacaa aaaaatagcg tcatttatta
     5821 ctctggaatt atcaggtaga tttgaacatc ttcggctgat ggaagaaatt gctaatattg
     5881 taggtgttat ttatgtcgaa gaaattagct gaaatttagt aaacaaaggg acagatgttt
     5941 ttgtcctttt gctttttaga tgttttaatc atctaatttt tgagtagatt tttgctcaga
     6001 ggtttttatg aaagattata aaatcaattt tgatttaggt aaaatagaat attttgataa
     6061 taattgtttg atacaagtat acaaatttat ttctttttat gatatttgtg aaatggtgtt
     6121 tgcctttcat ttacctcctg atgagttgat aacaaatgtt atctttaaag aaaaaattaa
     6181 ctctatgtta aaatgttaca ttgacaggct attatatgtt tttataaatc ctacacattt
     6241 tactgaaaaa gttaatctac aattttatag cagttttttc tcatatgaat ttatttgtcg
     6301 tgaagttgga aacattctta aaaataaagg tgtgaaatgc aatttaaact tttttgaagg
     6361 ggaagaatat ttgtaaaatt aattttgtga atttgtggat cttaaataat ttactaaatt
     6421 ctcttgttaa aaaaaattaa atattgtata gtaatattag aatgtttgta atagaggact
     6481 gaaatgaaaa atataaatgg gaaaaaggta actatttatg atattgcacg tttatcaggt
     6541 ttttctccaa aaacagtttc acgagttatt aatggtggag taaatgttaa agaagaaact
     6601 tatcaagcga ttcaaaaagt tatagaggaa ttgtcgtata ttccaaatgc gtatgcaaaa
     6661 aatttaacta aaaaagaagc tataaatata ttgatttctg taaaaaaaat cgactctttt
     6721 cctttaattt ggtttcatac gctgttagat aaagtgttac ggacgtgtaa agaatttggt
     6781 gttaatgcta tagttgagta ctttggagag gaggatacaa ttagtaattc gattatatca
     6841 agcacaggta gcctagtaga tggtgttatt gttttttatg aaagtgtaga tgatatcaga
     6901 attcagtatt taaagaagaa ccatatgcct tttcttgttt tcggtgaatc tcaaacgtct
     6961 ggagtagtct atgtatctaa taataatttt caagctactt atgatatgat gaaagctgta
     7021 actgaagaaa aatttaaaaa tatgtggttg cttatgggag gagaatctca tgttaataag
     7081 gatcgtgaaa gaggtgtgcg ttcttttctg aatgataaaa attactttat ggatttaaaa
     7141 gtcatttatg gattatctac aattgattca gtttattctt atgcaatgca gcacttgact
     7201 acccaaaatt atccggacat tatttttgtt tcaggagatg aaaaggttca gggcttgatt
     7261 cgtgcgtgct atgagaaagg aattcttatt ccagatgata tttctattat tggatttgat
     7321 aatattccta tttctcagta ttatactcca gctttgtcta caattgctcc caattatgtt
     7381 aaattggcta aagaaatgat agaaggtgtt ttagcaatta ttaaagggga aagtgtcaca
     7441 tctgttgaag tttctcctaa atttgttagg agacagagtt tctagtattg tttaattctt
     7501 gaaaatccta gtggaaaaga tggagtgttc taaaataagt tctgtttagc ctccattcag
     7561 tttctattga gttggatcca atttctaaca agtgggacat gttcatgttc gatctaagga
     7621 agacatggtc acattcgaat gatattttca aaaaaatcgt aaaaaagtct tgacaaagaa
     7681 aaaacaaagt attaaaataa gttcaacaaa tcagaaaagt aactattttt gatcttcagg
     7741 gagcctgtgg tggttgtgaa taggtggttg gaagtagtga aagtgggctg attttgaaaa
     7801 tgaatttgaa ataatgaaaa ttcggtgcgc acaccttaca gtgcagcttg ttgttaaaca
     7861 aggcagagat gtaaagggat agtcccttta taattgaggt ggcaccgcgt taccaacgcc
     7921 ctcacacgga agtatattct gtgtgtgggc ttttttctat ccgtcgtttg gtttatcttt
     7981 tattagggcc ttaagtcgct ttgatgaact tgagttctat ctacagctcc ttgcctacta
     8041 ctaaaagcaa acaaaaaggc tggactaata cgaaaaaagc tagtaatact caatgaaaat
     8101 caaagagcaa actaggaaac tagccgcagg ctgctcaaaa
//
LOCUS       DBEROT010000064         7953 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.64, whole genome shotgun sequence.
ACCESSION   DBEROT010000064 DBEROT010000000
VERSION     DBEROT010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.64"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(86..2632)
                     /locus_tag="ACL8CG_001999"
     CDS             complement(86..2632)
                     /locus_tag="ACL8CG_001999"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGS1344536.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLAAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(2755..3195)
                     /locus_tag="ACL8CG_002000"
     CDS             complement(2755..3195)
                     /locus_tag="ACL8CG_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGS1344537.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQIHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(3170..4039)
                     /locus_tag="ACL8CG_002001"
     CDS             complement(3170..4039)
                     /locus_tag="ACL8CG_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGS1344538.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYCFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGINDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(4017..4517)
                     /locus_tag="ACL8CG_002002"
     CDS             complement(4017..4517)
                     /locus_tag="ACL8CG_002002"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1344539.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(4528..5226)
                     /locus_tag="ACL8CG_002003"
     CDS             complement(4528..5226)
                     /locus_tag="ACL8CG_002003"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGS1344540.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(5219..5455)
                     /locus_tag="ACL8CG_002004"
     CDS             complement(5219..5455)
                     /locus_tag="ACL8CG_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGS1344541.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(5555..6481)
                     /locus_tag="ACL8CG_002005"
     CDS             complement(5555..6481)
                     /locus_tag="ACL8CG_002005"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGS1344542.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(6556..7371)
                     /locus_tag="ACL8CG_002006"
     CDS             complement(6556..7371)
                     /locus_tag="ACL8CG_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344543.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(7375..7695)
                     /locus_tag="ACL8CG_002007"
     CDS             complement(7375..7695)
                     /locus_tag="ACL8CG_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS1344544.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         2354 a         1823 c         1402 g         2374 t
ORIGIN      
        1 agcttagctg acttcaaccc actacagttg acaaagagcc cattttacat gagatagctg
       61 agttttcttt ttattttagg cttatttatg catttccgta ttgaagaaca actgcttcga
      121 ctgcagcttt ttcacggcta atcaagtcaa cacgcgctgc aatttccttg attcccatac
      181 cgatgttacg gctaagagca aggtcagaaa gttgcggttc aaagaactcc ttgtattccg
      241 ccaagcgttg ctgagtctta aatacatgag caggaaggat aacaaagcta tcaaagctca
      301 tatctcctcc aagggctgcc ttaatccaag cccagttttc acgcgcccaa gaccaagctg
      361 ttttctgagt tgcttgatga gctaggaatt ggtaatacca agcagacaag tcctgtggtt
      421 tgaccacaaa tttgtccttc caagaagtaa tcaagttttg gatattatcc gcatctgtac
      481 tgtatgcaag agctgctgcc aactggcgtt taaagacagc atctgttgcg tgagtataag
      541 tatcaagata aagtgctaac aagtctttag tctcatgatg tttcatctca ttaatcagaa
      601 cttgtgaacg aatagctgct gggagtcctg caagattctc cttgtgtgtt gcgaagattt
      661 ggctagcgac ttgactagct tctgcatcat ttgagcgaat catcatcgaa acagccagct
      721 gacgaaccaa ttcatcctca tctgattctc cgtctttagc ttcaaaacca agacggtcat
      781 agttatgacg agccaattta gcaaccagtc ctttgaaggc tgtttcagca tccgttcctt
      841 catcaataaa gcgctcaagg gctgaaatca cttgagaaac agctgaaacc accagataag
      901 actcttcctt agcaagttta tcaagaactg gaagcaagtc tgcataagaa atgtgccctg
      961 cctcagccaa caaacgacgt tcttgaacaa tttgcagttt gcttgtgtta tcaagtgtct
     1021 ctagctcagc aagaacagct gctaacaagt ctccttgata gtcggtaata tagtgggcag
     1081 tattttcagt gttgagacga agagctcctt cattttcagc aagaagagct gcgtagccag
     1141 ggatttcgat actttcagtt tcgagtgtat caggcaagcc tttccagttg ctattgaggg
     1201 gcaccaccca gagacggttc ttgtcttcgt tctcaccgat gaagaattgt ttttgtgaaa
     1261 tcttcaagac atcattttca actttgacag taagaactgg gtaaccaggc tgttccaacc
     1321 aagaatccat gaaggctgcg acatcacgtc ctgacgcttg accaagggca tcccaaagat
     1381 cactaccaat ggtgttgctg tattggtgtt tttcaaagta ggcatgcaaa cctttagcaa
     1441 aatcagcatc tcctagccaa cggcgaagca tgtgcatgag acggcttcct ttggcataga
     1501 cgatagcgcc gtcaaagagt gtattgattt catctggatg tttaacttcg acgtggacag
     1561 actgaacgcc atcagtagcg tcacgttcaa gagcaagagg tactccacct gtttggaaat
     1621 cttcaaagat attccagctt ggttcgatgg tatccacaca gacgtattcc atcatattag
     1681 cgaaactttc attgagccaa aggtcatccc accatttcat agtcacgagg ttcccaaacc
     1741 attggtgagc caattcatgg gccacaacaa gggcaacttg ttgacggcta gcaaatgtag
     1801 agttctcatc gacaaccaag taaacttcac ggtaagtcac aagaccccag ttttccatag
     1861 caccagctga gaagtcagga agggcgatgt ggagagattg aggaattggg tacttaactc
     1921 catagtaatc ttcgtaaaac tcgatagagc gaacagcgat atccagtgag aaatcaagat
     1981 ttgaaagtgg atgtgctttg gttgagtaga cacctaccag ggtaccattt ttagttttag
     2041 cggtcacccc ttgcaaatca ccagcaacaa aggccaacaa gtaagaagac atgcgaggtg
     2101 ttgtctcaaa cttccagata cctgtttcct tacggttttc aacatcgatt tctggcatgt
     2161 ttgacaaggc caattcacct tctgcttggt caaagcgaag agagaggtca aaagttgctt
     2221 tggcttcagg ctcatccaca catgggaaag cttcgcgcgc aaaatggctc tcgaactgag
     2281 tagacaagac ctccttcttg actccatcaa ctgtataata agaagggtaa atccctgtca
     2341 tgttgtctgt aattttacca gaaaaggcaa gaaccaattc aacttgacca gcctcagcca
     2401 attcgatatg aagggcttca ttgtcatggt caactgtaaa tggacgagct tgacctgcaa
     2461 cttctacaga ggtgatttcc aagtcttttt ggtggaggga gatgcggtca ctctgtgctt
     2521 gaccagtgat ggtcactttc ccagaaaaag tcttggtctc acgactcaaa tctaaaaata
     2581 aatcataatg ttcaggaaca aattgcttaa taaaatgttc aactgcttgc atagttttct
     2641 cctattctaa gtttaagagc tgctgctctt cttcaaacaa acttattata tcatattttg
     2701 cttgagaaaa aaggattgga cagcgatttc caaaactttc ttccttctaa tagtctacag
     2761 tgggtagacc ttgcgaaatt cttctaaaac aaccttgctt tcaggtgtaa aagtcagccc
     2821 tacttcaccc aaacagtctg tgaaaaagtc ctcatgaatc tggcgccaat aggcaagtga
     2881 tttgtctccc tcaccttcct taaaggcatg ttgcgcagaa acttgattga agagttcaac
     2941 agaaaccttt gtaatttcga caatgcagac agactgattt tgactatcta aaatgacatc
     3001 gaaggtccct acttggggaa gtggttcgtc ttctagtaca tagaggtcat aggctgatgc
     3061 tgttgctgtc ttttctcctt taaacaccaa atccgctaaa aggtctggtt caactccaaa
     3121 agcccaagca tcgatttcat ctccgatcaa aggattgatt tgcttgtatt tattccacat
     3181 ttcttgcggt atcatgggta ctcctttgta attttttact ttcttctttt atgtgtttaa
     3241 gatgatctgg atggtcaatc tctaaatcaa aaatctctgg aatagaactg tagtggataa
     3301 tgcacttgat acccaactga ttcatttttt gtatgaaaga agtattcaga tagcctgcta
     3361 cagcaaaatt aatcttgttc tttcttgctt tatcctgcat atctcttagc atatctaaca
     3421 ttattggact ttccagatca tgccattgac tgtttctcat agtcgcaaaa acaaaggaag
     3481 tcaaatcatt tattccaact acaatctttg aaatgcccgt ttccagtata ctagataagt
     3541 caaaatacgc tgacggtaat tcaatcatcg ttccgacttt cccagtaaag ccatactgac
     3601 gcaatactgt aatagcttgt tttaattggt cggcatcatt gacaaaagga aagataagag
     3661 acagattggg gttggtttga taaacttctg taacgacatg tgcttcagcc tgaaattcat
     3721 ccaaacacgc cagtaaacgc ctggttcctc tatagccaaa caagggatgc ccttcgtcaa
     3781 aaaactcttt agtccccact aaacaattgg cttctgtatt cgttaattca gtaaaacaat
     3841 accaaacttc ttcatctgag tacagggagc agatagtctc tagataatct tttacaaatt
     3901 gctgacaact tgctaatatg atgttttgat taagctctct caacaaatat tccccacgaa
     3961 tcatgccgac gtggtgaaat agttgaggat aaattttttc aagaattttt tcgccactaa
     4021 gggcaagttg atttctcatc attcaccttc caattcatgt aagaagtctt gtccagttct
     4081 ggaaatccta ataattcaga cttaaccttc aagactaatg gcgatgcatt ttcttctgta
     4141 atctcttgaa tatccatcca aatatatcca agtgaatcat tcgcaccatc agacacagct
     4201 tccgaagtcg taacttgagg tgcactctca ttcatttcaa catcatacaa ggccatgaca
     4261 tggtgaacca taaaatttgt taactcttct ctgacgaaaa catcgtagat tcgaggatta
     4321 gagtagcttc taacagtaaa tcccgtctct tccataactt ctctagtcag cgtttccgtc
     4381 agtccttcac caagttgctg actgcctcca ggtagatcat accgatgttg ataagggcct
     4441 ctcgcttttt caatgcagag taacttccca ttttctaagc aaacagcgta gactccaaag
     4501 tgttttttga tttccatcca actcctccta cttcaaagac cagccaccat ctattgtcaa
     4561 gatttgtcct tgcatggcgc tcgcttttcc acttgctaaa aaaagactaa gctctgctat
     4621 ttcctctggc tcaatccagc gcttgattgg ggtttcacta gccacccagt cagccaaacc
     4681 acctggttca aaatccgcag cggtcatagc tgtcttgact gctcctggag cgatcccaaa
     4741 gacctgaatc ccagcttcag catagtctag agccaactgc ttggtgaagc cagccaaggc
     4801 atgcttggat gaagtatagg cgtgaccacc tccacctgct aggctagaag caatggaaca
     4861 catattgatg atgattccct ttttattttc cagcatttgt gtcaaataat accgagtcaa
     4921 ctctactgga ataatgtagt tgatttcaaa aatctcttga atgtcctgcg ccgtttgttc
     4981 caacagtggt ttgtaatcat ccaaaactcc ggcagtatta cacaaaacat ccacctgagg
     5041 gcaccagtca aaaataggtt ccaagtccaa ggtcaaatct ctctgtaaaa agtgaaaatc
     5101 accctctaag agtggctttt caccttggtc aactccataa acttgatagc ccttctctaa
     5161 aaagaggcga gcttgagcca atccgatccc tgaactcact cctgtaatga gtacacgttt
     5221 agtcatgcac ttctacccaa tccgttgcca aaacatcaca agctgtcggg ctccacatgg
     5281 aaaaaccttc tccttctcca gacacgttga ttaggaaata gggtgtcact tcaagtgcaa
     5341 gcccattttg ctcgatggta tcaaagagtt ggacatagtt ttcagcacct ccccaaccag
     5401 ttcgtacata ttttttctta gcctttaagc caggtagaat ttcttcaaat gtcatgtttt
     5461 tctcctttaa tgtcaataat tctccccttc attataacaa aaaaaccgct ttaaaacggc
     5521 tttttgactg tgatttattt acatcttctt ctacttacgg caaattattc cctgcagcaa
     5581 gataaatttc ataccattct tttcttgtta agctaaagtt tgccgcttgg ctaacttctc
     5641 tcaagtgctt aggatttgtg gtacctacaa ctgcctgcat ttttgctgga taacgcaata
     5701 tccaagaaat ggcaatagtt gaagaggtta ctccatattt aatagctaaa cgatcaagta
     5761 cttgatttaa agcttgaaat ttctcatttc caacaaaatt ccctttaaaa tacccgaatt
     5821 gtaagacaga ccatgcttga atgaccacat cgtgtaattt gcaatattca aaaatgctgc
     5881 catctcgcat agctgcttga ctatcttcca tattaacatg aaaagctgat tcaaatcctg
     5941 gagtaaaagc cgcactcaat tgtagctgat taacagctaa cggctgcttg acatcttttt
     6001 taagcaactc catcatcata ggattttgat tagaaactcc aaaatctcga actttacctt
     6061 gtttataaag gagatcaaag gcttctgcta cttggtcaga ttccatcaaa gcatctggtc
     6121 gatgaaggag caagctatct agatgatcaa tcttcaatct ttgcaaaata ccgtctactg
     6181 attttataat atagtcctta gaaaaatcaa aataggtaaa ttcttcaatg cgaatgccac
     6241 atttggactg aatccacatc ttttctctta aatctggacg attttttagg acaagaccta
     6301 acagttcttc acaacgacca cgaccataaa tatcagccaa gtcgaaggca ttgattccaa
     6361 cagaaagtgc tgtttctaca agctcttcaa cttcttttac agacttatct tttattctca
     6421 tcattccgag aacaatttct gataattctt tgtcatcttg accaagagtt atgtatctca
     6481 tcaaattttt ctcctttaat ttctaacatt cttcccttca ttataacaaa aaaccgcttt
     6541 gcaacggctt tttgactata cttcactcca ttttatcttc ttaaacccac ggaacaagac
     6601 aaagattcca ataaagagga cagctaaagg aataactttt gtaaggaaaa catttgaaat
     6661 tcccatccac tcataataac ggagcagaga acccaccaca agatgggcaa taatcatact
     6721 gacaaatgga cgaaagaccg cttctttcca attccaaata ccgataacta gcgaaatcgt
     6781 aaagacagac aaactatccc agggagccgg aatataaaag gctccttctt gtatgaagct
     6841 tgccattcct acatatccta aaacaactag aagaactata gtcccaacaa caatgtaagt
     6901 gccaattttc attttaggag aatcttggac taaacttctt cgtaaaattg tggccacaag
     6961 tccaaatcca atcagaaaaa taagaagttg ccctaaaaat gtgagcaaat tgactgttaa
     7021 gagaggacct ttagaaaaat cacttagtag ttgataataa cgtaataccg ccaggacaag
     7081 aattggcgtc aaaagggact ctttgataga actgcgaggt gctcccttga gaatctcttt
     7141 cattattttt ttaggattct tacctagata atcctctgca ctcatgccat ctcgttctgc
     7201 ttctgagaaa tctagcatca tcaaatagat ctgctctctg agatagtctt catcatagag
     7261 aaatccagca agattaaaac tttcccacaa ctcctcaaaa tacttttgat tctcctcaga
     7321 aaactcatgt agcaaagcgc ttgtttcttc gtaatacttc attttcttca tggtttaacc
     7381 cccattctta atcccttcta ctttttgact caaatcgtcc cattgttgcc aaaagactga
     7441 gacacgctct tctccttctt tcattaatga aaaatacttc cgatctggac catctggcga
     7501 cgggcgcatg tcgcctctta tccattgatt tttttctaac ttttgcaaca aaggataaat
     7561 agttcctgga acgatagtat caaatccagc ctctcgcaaa gtctgaacca actcataacc
     7621 ataccgctct ttttgaccaa tcatatccaa gacacaacct tcaagaacac cttttaatag
     7681 ctgagtttct ttcatcactt ctcccttcta atctattttg taatacctac tagtaacttc
     7741 acctatagta tatcacttct acactagttt gtaaagcata atagttaata ctcttcgaaa
     7801 atctcttcaa accacgtcag cgtcgcccta ccgtatgtat ggttactgac ttcgtcagtt
     7861 tcatctacaa cctcaaaaac atgttttgag ctgacttcgt cagtttcatc tacaacctca
     7921 aaaacatgtt ttgagctgac ttcgtcagtt tca
//
LOCUS       DBEROT010000065         7777 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.65, whole genome shotgun sequence.
ACCESSION   DBEROT010000065 DBEROT010000000
VERSION     DBEROT010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.65"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(52..3894)
                     /gene="spuA"
                     /locus_tag="ACL8CG_002008"
     CDS             complement(52..3894)
                     /gene="spuA"
                     /locus_tag="ACL8CG_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGS1344545.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATSPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDETGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLREEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            4311..4724
                     /gene="rpsL"
                     /locus_tag="ACL8CG_002009"
     CDS             4311..4724
                     /gene="rpsL"
                     /locus_tag="ACL8CG_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGS1344546.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            4744..5214
                     /gene="rpsG"
                     /locus_tag="ACL8CG_002010"
     CDS             4744..5214
                     /gene="rpsG"
                     /locus_tag="ACL8CG_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGS1344547.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            5639..7720
                     /gene="fusA"
                     /locus_tag="ACL8CG_002011"
     CDS             5639..7720
                     /gene="fusA"
                     /locus_tag="ACL8CG_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGS1344548.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
BASE COUNT         2130 a         1561 c         1737 g         2349 t
ORIGIN      
        1 ttaatccccc gagctataat gcttggggga tttttctata ggagggctag cttagttctc
       61 ttttttattt tttagtaaga aaccgagacc aaggagcgca aggaggctga ttcctgcaaa
      121 taggagtttg ttttcgtttt tgattcctgt atttggaagt tcagcttgtc tatctggggt
      181 tgcagatata ttttccttgc tagagttttc taccgattct tttcgaaccg cttcttttac
      241 agatgatgct tgtgcttctt gtgctggttg ttcagcttgt gaatcagctg tagcttggct
      301 aggtttattt tccgcatcag ctactttggc atctggttta gtagaatcag gtctagcttc
      361 tggagctggg tcttgatgtg cagggtgaga agcttcattt tgatgttcag gcttggaagg
      421 ggttgagtct ggtttctctt ctgcagttga ctcatggcta gttccatttt gagagactcg
      481 aagaacagta gctgtaaggg cattcaattt caagcctttt tcagtccatt caagtccttt
      541 cgggttggca attccgactg atcctgcttg gttttcatct gccaaaactt ccgcatttct
      601 tagatgtgca aaggcagttc ccaaattaaa ttcgcgagct ttttcatccg cattgacaaa
      661 gactgcgtag atatcgccgt ttggagcagt gatttggtag ccaatcacta catcctcttt
      721 ttccacacca ttttggcctg ggacagtgat gaggtggaca cggtctttga tatcttggag
      781 actcttaagt cggaaggcat ctgtagattg acgaagggca atcaaacctt tcatatagtc
      841 acggctcttg acattttcag gataagcttt accatctgta gccttagtcc agtcaaactt
      901 gttgactgcg tcgctagaat cgtaagaatc atggatgaag taaggatagt caaatgggtt
      961 gccgtcctta tcacgcaaca agtgagattt gtttggaacc ttatcctctg ctactggagt
     1021 cttgtaggct gggtcacgga attgtttagt acgtccatat tcctgaccgg agtggataaa
     1081 tggagttcct tgagctgtca agaccatgag atttccaagt cgtaaacgac ggtggatttc
     1141 agcatagttc tcagccttgc ttgggtcttt tttgatagac tgggcaatga tgtcaaagag
     1201 ggtcaagtta tcatgggctg cgatgtattg gatgacatct ccagggctgt cagcttcaaa
     1261 gttagttggt tgagcaatga gatttttaaa gatggtgttg acatcacgct tgccacctgt
     1321 gataaaggca ggttgacctt cgtttggata accagatttg aggttgttac ggatgtcatc
     1381 tgaaaagaca gcgacagtat cggtatgttt catccaatct tggtcagcag ctttagtagg
     1441 catgttttca tcaccggcat aggttctcca accttcgcct aacatgatta gatttggatt
     1501 gagggcgcgt gcagccttgt aagcttcttc gatagaagcg gcgtcatggt ctcccatcat
     1561 atcgaagcgg aagccatcca ctttgtaggt atcaactagg tatttgatag agtcaactag
     1621 gagccgtttg gtcatatggt gggttgtccc caagcgtcca ccaccaaagc tagttcgagg
     1681 tgtgccatcg gcatccataa agtggtagta gtttggctct aggtcttcaa agatatcgac
     1741 tttggctgtg tggttataaa cgacatctag gatagctccc ataccacgtt tgtggatttc
     1801 gttgatgagg tttttaaatt ctgcgattcg tttttctgga ttcttaggat cgcttgagta
     1861 cataccagtc aaggagaagt agttttgagg gtcatatccc cagttgtagt tgctgttgct
     1921 tgaagcatag tcagacaagc gttcatggtt tttcaattca ttgacaaagt agtaagacaa
     1981 gactggaagg agctggatat gggttacacc caagtctttg agatagtcta gtttttcaat
     2041 gaaggcttca aaagtcccaa atggtttggt caagtctttt gcaatggcag gatctgaagt
     2101 gaagtcacgc acatgagctt cgtagataac ggcgtcttca cgagtcttga aattgtgaat
     2161 cttaccataa gtcaagtctt gaggtccgag tttagctgga tctacaaagg cggctttagc
     2221 cactttatgg gcatcgtcaa tcttggcatc gtcgctattc caagcagcaa gagatttagc
     2281 gtaaggatcg agtgcaagaa cagttttacc ttgacgctcg atttggtatt gataatagta
     2341 gccagtgaaa tctgtgattc cgagtttgtt tgtgctgtct agagtttgtt tccaagttcc
     2401 tctttcccct ttttcgagag cgacagttcc aactactttg tcagggtcat tcttgtcgta
     2461 gacaacaaca gaaaccttat cagcacttgg tgaccaaagg gtcaaatcaa cttgttttcc
     2521 ttcttctctt aggtcagctc ccagtttgcc atcatagctg tatgtctcat ctttcaggcg
     2581 ccagcttgtt ttggtagtga attgatcgga attgtagcta acagtataag gatgttttgt
     2641 gtcagagaaa tctccgctgt aggtcacttt cttaccagtt tcatcgattg caacatcggt
     2701 aatagttacc ttgtttccta ggtgattagt gatgttggag tgtttgagga tatcttcttt
     2761 tttagcaccg acaagtgttg aaaagctact ttcaatgcta gaagtgccta cgtgttgggc
     2821 tcctgtcata cggatatcat ggacatagta tggatttgtg taaatcgatt catcatcgtc
     2881 ttttaggaaa atttggctat gatttttcaa atctgtgaac ttataatttt ctttacggat
     2941 tttcacgtcg tctccttgtt tgctctcatc tagtaataaa aatccaaatt ctcttgcggc
     3001 ttcattaaga ggaatgtcga tatagcggcc atatttgcct gtagccgtaa agtctgttcc
     3061 gtcaggccat tgagcgctac ttggattttt tacatctccc cagtaccaga gagatttctt
     3121 gtcatagttg ccatctgtgc ggtagtagtt gacgcgaaca gttcctgcag gctgtggctc
     3181 gtaagagaaa accttgtaat cttggtctaa ccaagcttcg ttcatttttg gaactagttt
     3241 ttctacagat ttatcgccgg ttagattttt tccagctgta ttgttgatga ggaagctaat
     3301 tttcttggct tgttctccct ttaatttgac atctaggtaa tagccgtagt catctttctt
     3361 ggcatccttg aaggacaaag ctccgtttgg ccagttttca gatggttttt caacatcgtc
     3421 ccaagtccat agtccttgag catccttgtt ttcttcagga agttttttga catggatacg
     3481 gaagtagtta tcttcgatgg gctcttctgc cttagtttca gttgttactg gactagtaga
     3541 agtagttggc tcacttgaac gatcttgtcc agtttgtggt gctggatcgg ctgggcttgt
     3601 agcaggtttt tcttctgttt tctctaggga agcgtttgca tttctaggtg aagaaatatc
     3661 actttcgttc ttaccagagc cagctgctgt atcagtaaga ggttgagcaa gggtggttgt
     3721 atttctgttg ttgggttcgt tagtggttgg tgtactttcg tcggatgaga tagttggtgt
     3781 agccatggca agcaagacaa ggcttgcgcc gataaggaca gaaccagttc catttttgag
     3841 ggaacggatg ctgtagacca tttttttctc agtgtgagat ggtgtttttc tcataatgat
     3901 tctccaatca ataaatttct atatcagtat agcatgtagt aaaacaatat gcaagcgttt
     3961 tctttgattt gtgaaaaaaa ttcctacttt tgagaagttt tctgtactat tttatatatc
     4021 agtataaatg acggagataa aaatgtcaca taagccaagc cgtattatta ggaagatgat
     4081 gtgttcccag ctatttttat tcagaaattg atctctaaca ttaccaataa aaatgaaaaa
     4141 tatcttgaca agcaagggaa aattttgtta caataataga cggtactttt tacttttggt
     4201 ctctcaagag tgtacaggga cgtgctgaca aatgttgcaa aagtacacac agatgatatc
     4261 tgtcaccaag tgtatcatca ccaaaaataa aaaaacacag gagaatgtag atgcctacaa
     4321 ttaaccaatt ggttcgcaaa ccgcgtaaat caaaagtaga aaaatctaaa tcaccagctt
     4381 tgaacgttgg ttacaatagt cataaaaaag ttcaaacaaa cgtttcttca ccacaaaaac
     4441 gtggtgttgc aactcgtgtt ggaacaatga cacctaaaaa acctaactca gcccttcgta
     4501 aattcgctcg tgtacgtttg agcaacctta tcgaagttac tgcctacatc ccaggtatcg
     4561 gacacaactt gcaagagcac agcgtggtgc ttcttcgcgg tggacgtgta aaagaccttc
     4621 caggggtacg ttaccatatc gtccgtggtg cacttgatac tgcaggtgtt aacgatcgta
     4681 aacaaggccg ttctaaatac ggtactaaac gtccaaaagc ataaggaaag gggataaaga
     4741 gaaatgagtc gtaaaaatag agctccaaaa cgtgacgtat tgccagatcc gctatacaat
     4801 tcacaactag ttactcgtct tatcaaccgc gttatgcttg atggtaaacg tggtactgct
     4861 gcttcaatcg tttacggtgc ttttgagcaa atcaaagaag ctactggcaa cgatgcactt
     4921 gaagtatttg aaacagctat ggaaaacatc atgcctgtac ttgaagtacg tgcacgtcgt
     4981 gttggtggtt ctaactacca agtcccagtt gaagttcgtc cagaacgtcg tacaacactt
     5041 ggacttcgtt ggttggtaac aatcgctcgt cttcgtggtg aacacacaat gcaagaccgt
     5101 cttgcaaaag aaatcttgga tgctgctaac aacactggtg cagcagttaa gaaacgtgaa
     5161 gatactcacc gtatggctga agctaaccgt gcattcgcac acttccgttg gtaagatagg
     5221 atgcgaaagc gttaagaaag tcccagagaa aatagggaat cgaagcaggt tgcggttgca
     5281 accaatgaga ttcatctttt tctccagact tttagcttga gctcaactaa atcatgatgc
     5341 taggcacggt aaggatgcaa ggtgaaaata ggaaactgac gcagtattca acgaatacaa
     5401 ggagttttat ctttttcacg cagcatcccg ttccagctca catcggctaa ctaactttag
     5461 cctgggttca aattagctaa atcgattagt attagctata actcagctta ccatctcgta
     5521 agttgaaacc aacaatagca tgaaaacatt gagaacgggt aggtcctgcc tatccgtttt
     5581 tattaaaatc gtgttataat agaatagaaa tcaaaaataa ataggagaaa caaacctcat
     5641 ggcacgcgaa ttttcacttg aaaaaactcg taatatcggt atcatggctc acgtcgatgc
     5701 cggtaaaaca acaactactg agcgtattct ttactacact ggtaaaatcc acaaaatcgg
     5761 tgaaactcac gaaggtgcgt cacaaatgga ctggatggag caagagcaag aacgtggtat
     5821 cacgatcaca tctgctgcga caacagctca atggaacaac caccgcgtaa acatcatcga
     5881 cacaccagga cacgtggact tcacaatcga agtacaacgt tctcttcgtg tattggatgg
     5941 tgcggttacc gttcttgact cacaatcagg tgttgaacct caaactgaaa cagtttggcg
     6001 tcaagcaact gagtacggag ttccacgtat cgtatttgcc aacaaaatgg acaaaatcgg
     6061 tgctgacttc ctttactctg taagcacact tcacgatcgt cttcaagcaa atgcacaccc
     6121 aatccaattg ccaatcggtt ctgaagatga cttccgtggt atcattgact tgatcaagat
     6181 gaaagctgaa atctatacta acgaccttgg tacggatatc cttgaagaag acatcccagc
     6241 tgaatacctt gaccaagctc aagaataccg tgaaaaattg attgaagcag ttgctgaaac
     6301 tgacgaagaa ttgatgatga aatacctcga aggtgaagaa atcactaacg aagaattgaa
     6361 agctggtatc cgtaaagcga ctatcaacgt tgaattcttc ccagtattgt gtggttcagc
     6421 cttcaaaaac aaaggtgttc aattgatgct tgatgcggtt atcgactacc ttccaagtcc
     6481 acttgacatc ccagcaatca aaggtattaa cccagataca gacgctgaag aaactcgtcc
     6541 agcatctgac gaagagccat ttgcagctct tgccttcaag atcatgactg acccattcgt
     6601 aggtcgtttg acattcttcc gtgtttactc aggtgttctt caatcaggtt catacgtatt
     6661 gaatacttct aaaggtaaac gtgaacgtat cggacgtatc cttcaaatgc acgctaacag
     6721 ccgtcaagaa atcgacactg tttactcagg tgatatcgct gctgccgttg gtttgaaaga
     6781 tactacaact ggtgactcat tgacagatga aaaatctaaa atcatccttg agtcaatcaa
     6841 cgttccagaa ccagttatcc aattgatggt tgagccaaaa tctaaagctg accaagacaa
     6901 gatgggtatc gcccttcaaa aattggctga agaagatcca acattccgcg ttgaaacaaa
     6961 cgttgaaact ggtgaaacag ttatctcagg tatgggtgaa cttcaccttg acgtccttgt
     7021 tgatcgtatg cgtcgtgagt tcaaagttga agcgaacgta ggtgctcctc aagtatctta
     7081 ccgtgaaaca ttccgcgctt ctactcaagc acgtggattc ttcaaacgtc agtctggtgg
     7141 taaaggtcaa ttcggtgatg tgtggattga atttactcca aacgaagaag gtaaaggatt
     7201 cgaattcgaa aacgcaatcg tcggtggtgt ggttcctcgt gaatttatcc cagcggttga
     7261 aaaaggtttg gtagaatcta tggctaacgg tgttcttgca ggttacccaa tggttgacgt
     7321 taaagctaag ctttatgatg gttcatatca cgatgtcgac tcatctgaaa ctgccttcaa
     7381 gattgcggct tcactttccc ttaaagaagc tgctaaatca gcacaaccag ctatccttga
     7441 accaatgatg cttgtaacaa tcactgttcc agaagaaaac cttggtgatg ttatgggtca
     7501 cgtaactgct cgtcgtggac gtgtagatgg tatggaagca cacggtaaca gccaaatcgt
     7561 tcgtgcttac gttccacttg ctgaaatgtt cggttacgca acagttcttc gttctgcatc
     7621 tcaaggacgt ggtacattca tgatggtatt tgaccactac gaagatgtac ctaagtcagt
     7681 acaagaagaa attattaaga aaaataaagg tgaagactaa tccgtcctca ctctagaagg
     7741 aagtcactta gtggcttcct tttgtcttta gaaaata
//
LOCUS       DBEROT010000066         7544 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.66, whole genome shotgun sequence.
ACCESSION   DBEROT010000066 DBEROT010000000
VERSION     DBEROT010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.66"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..470)
                     /locus_tag="ACL8CG_002012"
     CDS             complement(<1..470)
                     /locus_tag="ACL8CG_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS1344549.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYEAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKNSMTDIAHQLAISTSTVIRKLNDFHFKHDFSRLPEIMSW"
     gene            complement(689..988)
                     /locus_tag="ACL8CG_002013"
     CDS             complement(689..988)
                     /locus_tag="ACL8CG_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGS1344550.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            1390..2094
                     /locus_tag="ACL8CG_002014"
     CDS             1390..2094
                     /locus_tag="ACL8CG_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGS1344551.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     misc_feature    2153..2240
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            2276..2590
                     /gene="rplU"
                     /locus_tag="ACL8CG_002015"
     CDS             2276..2590
                     /gene="rplU"
                     /locus_tag="ACL8CG_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGS1344552.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            2606..2950
                     /locus_tag="ACL8CG_002016"
     CDS             2606..2950
                     /locus_tag="ACL8CG_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGS1344553.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            2967..3260
                     /gene="rpmA"
                     /locus_tag="ACL8CG_002017"
     CDS             2967..3260
                     /gene="rpmA"
                     /locus_tag="ACL8CG_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGS1344554.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(3586..3734)
                     /locus_tag="ACL8CG_002018"
                     /pseudo
     CDS             complement(3586..3734)
                     /locus_tag="ACL8CG_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            4213..5130
                     /locus_tag="ACL8CG_002019"
     CDS             4213..5130
                     /locus_tag="ACL8CG_002019"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGS1344555.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETIMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            complement(5223..6071)
                     /locus_tag="ACL8CG_002020"
     CDS             complement(5223..6071)
                     /locus_tag="ACL8CG_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS1344556.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            6212..7051
                     /locus_tag="ACL8CG_002021"
     CDS             6212..7051
                     /locus_tag="ACL8CG_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1344557.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            7158..7433
                     /locus_tag="ACL8CG_002022"
     CDS             7158..7433
                     /locus_tag="ACL8CG_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGS1344558.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
BASE COUNT         2369 a         1245 c         1528 g         2402 t
ORIGIN      
        1 tcccaagaca taatctcagg aagacgcgaa aaatcatgtt taaagtgaaa atcattgagc
       61 ttacgaataa cagttgaagt tgagatggcc agctgatggg caatatcggt catagaattc
      121 ttttcaatta acttttgagc aatcttttgg ttgatgatac gagggatttg atgattcttc
      181 ttgacgatag aagtttcagc aaccatcatt ttagaacaat gatagcactt gaaacgacgc
      241 tttctaagga gaattctagt aggcatacca gttgtttcaa gataaggaat tttagaaggt
      301 ttttgaaagt catatttctt catttgactt ccgcactcag ggcaagatgg agcttcatag
      361 tccagtttgg cgatgatttc cttgtgtgta tccttattga tgatgtctaa aatctggata
      421 ttagggtctt taatgtctag taattttgtg ataaaatgta attgttccat atgattcttt
      481 ctaatgagtt gttttgtcgc ttttcattat aggtcatatg ggactttttt tctacacaaa
      541 ataggctcca taatatctat aggggattta cccactacaa atattataga gcccaaagtt
      601 ttaggttgct tgatactatg cgttttttat aatttttgca cctttcttag cctttgttat
      661 cgacaagcat tgttctagct ccttgttttt agaaaggtaa tttcccagcg aaagcaccca
      721 gttttttctt ggtagtttca tcgatttgtt caagagcaga gttgatggct tgaacggtca
      781 tatcagaaag agtctcaagg tcctctgggt caacgacagc tggattgaaa tcaatgctga
      841 caactttctt atcgccagtt aaggtcgctt ggacaagatc ttgagcagat ttgccaacaa
      901 attgcatagc agcaagttca gcttggcttt gttccatttg tttttgaagt ttttgtgctt
      961 gacgcatcat gttttgcatg ttcatcataa gatttctaaa gttcctttca tctcaagggg
     1021 ataatccttg ttgttaacaa gtgcctgatt ttctctccta attgttatta gtagcatagc
     1081 catcaagccc aagtattgat tttattatac cattttttta agacatagtc ttttattggt
     1141 gagagttatt tatgtcaagg agtgattaga aataaattaa aataatgatt tttgctaaga
     1201 gggctctatt ctagtttcat ggaaatgatt ttactaaagg ttcgtatgct ttgtttgcaa
     1261 acatgttaca tctatctatt tttggataaa tagttgtcta ttattatttt tatgctaata
     1321 gtaaaatcta aatggtagcc tacgattttt tagaaagaaa atggtacaat atttctaaga
     1381 gaaaatacaa tgggaggtaa aatgaggtta ttacctataa gaaaaatatc acgtcagtct
     1441 aaaaggttag cacttttttt gacgttttgt gctggatatg tggatgctta cacttttatt
     1501 gttcgcggga atacccttgt agctggacaa actggaaatg ttgtctttct ttcagtagaa
     1561 ttaattaaaa ataatgtttc ggatgttagg gacaaggttc tcaccttgct agcgtttatg
     1621 atgggagtct ttttattaac gatttataag gaaaaattga gaattgtgaa aaaacctatt
     1681 ctgtccttga ttcccttggc aatcttatca atcattattg cttttgtgcc gcaaactgtg
     1741 gataatatct atctagtgcc gcccttggcc ttctgtatgg gactggtgac aactgctttt
     1801 ggagaagtgt cgggtattgc ctataataac gcttttatga cagggaatat caaacggacc
     1861 atgctggctt ttggagatta tttccgaacc aagcacactc cttttttgcg tgaaggattc
     1921 atatttgtta gcctgcttag tagttttgtc cttggcgttg tcttttcagc ctatttgacg
     1981 attttctatc atgaaaagac cattcttggt gttcctatta tgatgagcgt tttttacctc
     2041 agcatgcttt ttgcctcttg gcagaaaaaa gtaaaagaaa aagcttcatt ttaggtgtta
     2101 ttacttgtaa gaaaatagga gatatgctat acttgaagag ttgactatgc acgatcctgt
     2161 gcaaccgcac gaacatcgtt gcttgattat tcaagtttaa gtggttcgtc ccacgatgct
     2221 aggcgagtct tcacaaaaaa tcggggaaac ccataaaaat cataggaggt gcataatgag
     2281 cacatacgca attatcaaaa ctggcggaaa acaagttaaa gttgaagttg gtcaagcagt
     2341 ttacgttgaa aaattgaacg ttgaagctgg tcaagaagtt acttttaacg aagttgttct
     2401 tgttggtggt gaaaacactg ttgtcggaac tccacttgtt gctggagcta ctgtagttgg
     2461 aactgttgaa aaacaaggaa aacaaaagaa agtggttact tacaagtaca aacctaaaaa
     2521 aggtagccac cgtaaacaag gtcaccgtca accatataca aaagttgtca tcaacgcaat
     2581 caacgcttaa ttttaaggag aacacatgat acaggcagtc tttgagagag ccgaagatgg
     2641 cgagctgagg agtgcggaaa ttactggaca cgccgagagt ggcgaatacg gcttagatgt
     2701 cgtgtgtgca tcggtttcta cgcttgccat taactttatc aattctattg agaaatttgc
     2761 aggctatgaa ccaatcctag aattaaacga agatgaaggt ggctatctga tggttgaaat
     2821 accaaaagat cttccttcac accagagaga aatgacccag ttattctttg aatcattttt
     2881 cttaggtatg gcaaacttat cggagaacta ttctgagttc gtccaaacca gagttatcac
     2941 agaaaactaa cacggaggaa aacattatgt taaaaatgac tcttaacaac ttgcaacttt
     3001 tcgcccacaa aaaaggtgga ggttctacat caaacggacg tgattcacaa gcaaaacgtc
     3061 ttggagctaa agcagctgac ggacaaactg taacaggtgg atcaatcctt taccgtcaac
     3121 gtggtacaca catctatcca ggtgtaaacg ttggtcgtgg tggagacgat actttgttcg
     3181 ctaaagttga aggcgtagta cgctttgaac gtaaaggacg cgataaaaaa caagtttctg
     3241 tttacccaat cgcaaaataa aaaggttcat tgaacctttt atcccgaacc ttgaaatgta
     3301 aaggtgagga agctagaaac agcttaaaat aaggctttcc gagttttcgg agagcctgtt
     3361 tttttatttt gatacccata ctttttaata tgtatagtgg attgatactc ttcgaaaatc
     3421 aaattcaaac cacgtcaatt tcaccttgcc gtactcaagt acagcctgcg gctaacttcc
     3481 tagtttgcac tttaattttc attgagtatg aatctggaat agaacactgt taaaaattga
     3541 tatgagtttc ctactcgatt tcttcagatt ttatttcaat tgactataag aactgctatc
     3601 tggtttcaaa tattggcttg tcgtcccttc acttgtctga atggtttgag ccgttccttc
     3661 tgataaggga aaagatattc tttagctgaa acggtctgag aatccaagct aacagatgga
     3721 gagaaaaata gcccagtctg aagcacacta gatgggagtt gttggaaagc agtcatctag
     3781 tttttctttg ctgttttggc ttttttcttt gtcatcaggg aaagtgactt gcttcaaatc
     3841 agggagttta ggaaattctt caaacatctt gcccaagttg tctcattttg taaattttac
     3901 agccataggt gtacctcgat tctaaattct acctttttgg caccaattag taatttaaag
     3961 ttctcaggag ttagttgcat tgctttttca tacataacat agtatgacac tttatggtta
     4021 ccgaacaagt ctaatcactc cttgcaaaat tttgaagatg tcctacaagt ttttgagaag
     4081 aatattgcaa agttcatagt taagcaacga tagaataaag tgctttttga aaacaggtac
     4141 acttcatgtg aaaaaaacaa catttcagat tttctgttcc agaaatagct atcgctatga
     4201 tataattatt ttatgattat tactattcct ataaaaaacc aaaaagatat tggcacacca
     4261 tctgattcag tcgttgttct cggctatttt gatggcatac ataaggggca tcaagaatta
     4321 tttcgtgttg ccaacaaggc tgcgagaaag gatttattgc ctatcgtcgt tatgaccttt
     4381 aatgaatctc caaagatcgc tttagagcct tatcatccag atttgttttt gcatattttg
     4441 aaccctgctg aacgtgaaag aaaattaaag cgcgaaggtg tagaagaatt atatctcctt
     4501 gattttagta gtcaattcgc tagtctcact gcacaagaat tctttgcaac ttatatcaag
     4561 gctatgaatg ccaaaattat tgttgcaggt tttgattata catttggttc tgacaaaaaa
     4621 acagcagaag atttaaagga ttactttgat ggagaagtta tcattgttcc acctgtagaa
     4681 gatgagaaag gaaagattag ttcaactcgt atccgtcaag ctattttaga tggaaatgtg
     4741 aaagaagcag gaaaactttt gggggcaccg cttccatcaa gaggtatggt ggttcatggt
     4801 aatgctcgtg gtcgtacaat tggttatccg acagcgaatt tagtgctttt agaccgtact
     4861 tatatgccag cagatggcgt ttatgtcgtt gatgttgaga ttcaaagaca gaagtatcgt
     4921 gctatggcta gtgtcgggaa aaatgtgacc tttgatggag aagaagcacg ttttgaagtc
     4981 aatatttttg attttaatca agatatttat ggggaaacca tcatggttta ttggcttgat
     5041 cgcattcgtg atatgaccaa atttgactca gttgaccaat tagtggatca gttaaaggct
     5101 gatgaagaag taactcggaa ttggtcttaa gagcttgagt aaataaaaca aaaaagaggt
     5161 tgtctgtaac ccaaaagata gatgatttag tctaactttt gaggtcacga cattacctct
     5221 ttttattctt tttcaaaggt gaagccttct cctaggattt catgggcttc tgtaatagtt
     5281 ataaaggctt gaggatcgat tcgatgaatc atttccttcg ttttcacaat ttcatttctt
     5341 ccgacaatac agtagatgat tttcaaattt tctttactat agtagccttg accagaaata
     5401 aaagtaacac ctcttccgag gtcatcatta atcgccttag caagttggtc aggacgtttt
     5461 gtgataatca taaagccttt gccggcatat cctccttcac caatcaaatc aataacacga
     5521 gaaacaataa aatcaaacaa aagcgtgtag gaaaccaatc tcaaatcctt gaagattagg
     5581 agaatcaaca tgagaataca aaaatctaag ataaagagca gttttcctat ggatatatga
     5641 gtgtatttgt tgagaatacg agctagaata tcagttccgc cagttgtacc tccagcatta
     5701 aaaataattc caaggccaat tcccaatagg attcccgcta taagggctgt gattagtaaa
     5761 tcaccttgaa gatcaatatg aaggggaata tgctcaaaaa aagctaacca ggcggacaaa
     5821 gctaaggttc ctagtaaact agaatagagg gatttggctc caaagatctt ccaagctagg
     5881 atgaaaaggg gaatattaat cagcaggttc atgagggaaa cagggatttt aaaaagataa
     5941 aaggtgatga gggtaatgcc tgtcgcccct ccttcaaaga gatgatgggg aactacaaaa
     6001 taagtcagtc caaaagcata aatagcagca cctagtaaaa tggtaaaaat ggggtaaatt
     6061 tttttaatca taggacacct cttttcttat aagttgatta tatcaaattt tacggaaaat
     6121 ttgattgact ccattaggat ttttaatctt tttttgatat aattagaagt aaggaaacca
     6181 atctgaatcc taaaatagaa agattgatac tatgacaaaa attaagattg taaccgattc
     6241 atctgttact attgaacctg aactagtaaa gcaattagat attacaattg ttccattatc
     6301 tgtaatgatt gataatgttg tttattctga tgcggatttg aaagaagaag gtaaatttct
     6361 tcagttgatg caagaaagta agaatcttcc gaaaacaagt cagccacctg taggtgtctt
     6421 tgctgagatt tttgaagacc tatgcaaaga tggtggccag attcttgcta ttcatatgtc
     6481 ccatgctctt tcgggtacgg tagaagcagc acgccaaggt gctagcctat ctactgcaga
     6541 tgtgactgtt gttgatagtt ccttcactga ccaagccctg aaattccaag ttgttgaggc
     6601 tgcgaagtta gctcaagaag gtaaagatat ggaggcaatt ttatctcatg tagaagaggt
     6661 taaaaaccat acagagcttt atattggtgt ttcaactttg gaaaatcttg tcaaaggtgg
     6721 acgaattagc cgtgtaactg gcttgttgag ctctcttctc aatatccgtg ttgtcatgca
     6781 aatgaaagac catgaattgc agccaatggt taaaggtcgt ggaactaaaa catttaaaaa
     6841 atggttagat gagttgataa catcgctttc tgaacgtgct gtagcagaga ttggaatttc
     6901 atattctggt agtgatgatt gggcaaaaga gatgaaagaa agcttacaag cttatgttga
     6961 aaagccaatt tctgttttgg aaacgggttc cattattcaa actcacacgg gtgagaacgc
     7021 ttgggctatt ttgatacgtt accactccta aaaaaataaa taaaatggga agaaatagcg
     7081 tttttaactt gacctaaaag ggattttagg atatgattat atttgttaat tagaaattat
     7141 ttggaggaat cattaacatg gcaaacaaac aagatttgat cgctaaagta gcagaagcta
     7201 cagaattgac taagaaagac tcagcagcag cagttgaagc tgtatttgca gcagtagctg
     7261 actatcttgc agctggtgaa aaagttcagt tgatcggttt tggtaacttt gaagttcgtg
     7321 agcgcgcaga acgtaaaggt cgcaacccac aaactggtaa agaaatgaca attgcagctt
     7381 ctaaagtacc agcattcaaa gctggtaaag ctcttaaaga cgctgttaaa taatcagtct
     7441 ttaaaaagcc tattgtatca agctttctag cttggtcagt aggcttttta attatgaaat
     7501 ctagtaataa atagagttaa aaagttgaat gttccgaaaa tatt
//
LOCUS       DBEROT010000067         7406 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.67, whole genome shotgun sequence.
ACCESSION   DBEROT010000067 DBEROT010000000
VERSION     DBEROT010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.67"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..556
                     /locus_tag="ACL8CG_002023"
                     /pseudo
     CDS             1..556
                     /locus_tag="ACL8CG_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            617..1579
                     /locus_tag="ACL8CG_002024"
     CDS             617..1579
                     /locus_tag="ACL8CG_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS1344559.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPIESLCYE"
     gene            1756..2763
                     /gene="gap"
                     /locus_tag="ACL8CG_002025"
     CDS             1756..2763
                     /gene="gap"
                     /locus_tag="ACL8CG_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGS1344560.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2831..3706)
                     /locus_tag="ACL8CG_002026"
     CDS             complement(2831..3706)
                     /locus_tag="ACL8CG_002026"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1344561.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWKEIVNPGDVCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTF
                     TTLSNTFEKELKKNG"
     gene            3793..5988
                     /gene="pbp2a"
                     /locus_tag="ACL8CG_002027"
     CDS             3793..5988
                     /gene="pbp2a"
                     /locus_tag="ACL8CG_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGS1344562.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETKAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEASWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            6041..6193
                     /gene="rpmG"
                     /locus_tag="ACL8CG_002028"
     CDS             6041..6193
                     /gene="rpmG"
                     /locus_tag="ACL8CG_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1344563.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNLKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6203..6379
                     /gene="secE"
                     /locus_tag="ACL8CG_002029"
     CDS             6203..6379
                     /gene="secE"
                     /locus_tag="ACL8CG_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGS1344564.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6434..6970
                     /gene="nusG"
                     /locus_tag="ACL8CG_002030"
     CDS             6434..6970
                     /gene="nusG"
                     /locus_tag="ACL8CG_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGS1344565.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            7092..>7406
                     /locus_tag="ACL8CG_002031"
     CDS             7092..>7406
                     /locus_tag="ACL8CG_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGS1344566.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDD"
BASE COUNT         2330 a         1275 c         1609 g         2192 t
ORIGIN      
        1 atgggctaca ctcgaaaaaa agaaccacac ctactatgaa caagacccag aaaaagtagc
       61 cttatttctt aagaatttta atagtttaaa gcacctaaca cctgtttaga ttgacgaaac
      121 aggattcgat acttattttt atcgagaata tggtcgctca ttaaaaggtc agttaataag
      181 aggcaaagta tctggaagaa gatatcagag gatttctttg gttgcaggtc taacaaatgg
      241 tgagttaatc gctccaatga cttacgaaga gatgatgacg agcgactttt ttgaagtatg
      301 gtttcagaag tttttcttac caacattaac cacaccatcg gttattatta tggataatgc
      361 aagattccat agaatgggta agctagaact cttgtgtgaa gagtttgggc ataaactttt
      421 acctcttcct ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa
      481 aaagcacctc aaaaaggtat taccaagttg caataccttt tacgaggctt ttttatcctg
      541 ctcttgtttc aattgactat atatcacgga tacagttggg aaagaagcta ttaaatattt
      601 ggagagtcct tttgggatga acatgtcaaa tattactata gatgggcaag aaatggatct
      661 gagtcaaacg atgccttctt atgctcaagt agtgagtctt tatgatgata caagtatctc
      721 tgttagtaat aatgagacgg acaaagtgtt ggctggatcc ctctatactg atacaaatga
      781 acagggatta acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa
      841 tttgacagct aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc
      901 cgaaactagt aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga
      961 tgacatggag gacagcaaca gtttcatgct gtctcatcaa atggaaacga ttttgaaaga
     1021 ggctggattt acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac
     1081 aaaagtagta acagaagaat tacagaaaaa taagaagtat actgtgcttt ctcaacagag
     1141 agttcttgat attgtgatta cctttattcg tgttattcag ggattattga ttgtgctttc
     1201 atcacaagct attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat
     1261 gcaacgttcc aaggaaatag gtgtcatgaa agcagttggt tatcagaatc gtgatgtcaa
     1321 aggaattttt atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt
     1381 ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat
     1441 cactaaggtt tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt
     1501 acttggttat gtctcagcct acttcccggc gcgtaagatt agtaaaatgg atcctataga
     1561 atcgttatgc tatgaatagt aagggattcc ttggtttaca gtcttaaaaa gaaactaaca
     1621 tagaaaaaca atggccatac ttgcaattca actcaaatag ttgtataata ggtttgttga
     1681 aaggtgattt gtagtgattc aagttactct tttcacaata aaaatttcat gattttcata
     1741 aggaggaaat cactaatggt agttaaagtt ggtattaacg gtttcggacg tatcggtcgt
     1801 cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat caacgacctt
     1861 acagatccag ttatgcttgc acacttgttg aaatacgaca caactcaagg tcgtttcgac
     1921 ggtactgttg aagttaaaga aggtggattt gaagttaacg gtaaattcat caaagtttct
     1981 gctgaacgtg atccagaaca aatcgactgg gctactgacg gtgtagaaat cgttcttgaa
     2041 gctactggtt tctttgctaa gaaagaagca gctgaaaaac accttaaagg tggagctaaa
     2101 aaagttgtta tcactgctcc tggtggaaac gacgttaaaa cagttgtatt caacactaac
     2161 cacgacgttc ttgacggtac tgaaacagtt atctcaggtg cttcatgtac tacaaactgc
     2221 ttggctccaa tggctaaagc tcttcaagac aactttggtg ttgttgaagg attgatgact
     2281 actatccacg cttacactgg tgaccaaatg atccttgacg gaccacaccg tggtggtgac
     2341 cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta actcaactgg tgctgcaaaa
     2401 gctatcggtc ttgtaatccc agaattgaat ggtaaacttg acggatctgc acaacgcgtt
     2461 ccaactccaa ctggatcagt tactgaattg gtagcagttc ttgaaaagaa cgttactgtt
     2521 gatgaagtga acgcagctat gaaagcagct tcaaacgaat catacggtta cacagaagat
     2581 ccaatcgtat cttcagatat cgtaggtatg tcttacggtt cattgtttga cgcaactcaa
     2641 actaaagttc ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac
     2701 gaaatgtcat acactgcaca acttgttcgt actcttgaat acttcgcaaa aattgctaaa
     2761 taattcttga gttgatagaa agcaaggctt tgtggtcttg cttttttata tggaaaaatg
     2821 gatgacacga tcatccattc ttttttaatt ctttttcaaa tgtatttgaa agggtagtga
     2881 aagttagctt ctctaaagta agtgggtggg taaaggaaag tcggaaggca tgaagcataa
     2941 gccggcttgt ctttgattta ctattataga gagggtctcc caggatagga agattatgat
     3001 gcgaaaggtg cacacgaatc tgatgggttc gccctgtctt tagcttgcaa tgagccaagg
     3061 aagtcttgtt tgagaattgc tttaatctgc ttacatgcgt ttcagcatat tgcccatttt
     3121 ttgcatcaac tattcttttt ctacgatcat ggcgatcacg tccaattttg tctctgaaaa
     3181 caagttcttt tctgttgata tttccatcaa ctagagccca atattctcta gaaatctctt
     3241 ttttctccaa taagcgattg agaatgggca ggataaaagg atttttggca aagagaacta
     3301 agccactggt ttccatgtcc agacgatgaa cgacatagca ggtttggcca acataggtac
     3361 tgacatggtt aagaagggca atttcgtttg gttgattacc atgcgttttc atcccctctg
     3421 gtttgtttac aataatcaag tgttgatctt gataaacttc ctgcactaag tctgggttgc
     3481 cccaagggat cgtcttttgg gaataatctt cctcgtcaaa agtcaactgg caaacatctc
     3541 caggatttac gatttccttc cagtggactt cttcttgatt tatcaaaata tgtttcttga
     3601 ttctcaaaaa atgacggatt tttctaggga tgaggagttg ttcctcaagt aattgcttta
     3661 ctgtcatttg aggtagagag gcgggtaatg taaatgtgaa ttgcatacag atattgtaac
     3721 aaaaaaagcc ctatttggat aggaaatagc taaattcttg tcttcctatg atgaagatga
     3781 taaaataaac gcatgaaatt agataaatta tttgagaaat ttctttctct ttttaaaaaa
     3841 gaaacaagtg aactagagga ctctgattct actatcttac gtcgctctcg tagtgatcga
     3901 aaaaaattag cccaagtagg tccgattcga aaattctggc gtcgttatca tctaacaaag
     3961 attatcctta tactaggttt gagtgcaggc ttgctagttg gaatctattt gtttgctgta
     4021 gccaagtcga ccaatgtcaa tgatttgcaa aatgccttga aaactcggac tcttattttt
     4081 gaccgtgaag aaaaagaggc tggtgccttg tctggtcaaa agggaaccta tgttgagctg
     4141 actgacatca gtaaaaactt gcagaatgct gttattgcga cagaagaccg ttctttctat
     4201 aaaaatgacg ggattaacta tggccgtttt ttcttggcta ttgtcactgc tggacgttca
     4261 ggtggtggct ctaccattac ccaacagctg gctaaaaacg cctatttatc gcaggatcaa
     4321 actgttgaga gaaaagcgaa agaatttttc cttgccttag aattaagcaa aaaatatagt
     4381 aaggagcaaa ttctaaccat gtaccttaac aacgcttatt ttggaaatgg tgtgtggggt
     4441 gtagaagatg cgagtaagaa atactttgga gtttctgcat cagaagtgag tctggatcaa
     4501 gctgcgactc tggcagggat gctcaagggg ccggaactgt ataatccctt gaattccgta
     4561 gaagattcta ctaatcggcg cgatactgtc ttgcagaata tggttgcagc aggatatatt
     4621 gataaaaacc aagaaaccaa agctgctgaa gttgatatga cttcgcaatt gcacgataag
     4681 tatgaaggaa aaatctcaga ttaccgttac ccctcttatt ttgatgcggt ggttaatgaa
     4741 gctgtttcca agtataatct aacagaggaa gagattgtca ataatggcta ccgcatttac
     4801 acagagctgg accaaaacta ccaagcaaat atgcagattg tttatgaaaa cacatcgcta
     4861 tttccgaggg cagaggatgg aacgtttgct caatcaggaa gtgtagccct cgaaccgaaa
     4921 acagggggag ttcgtggagt tgtcggtcaa gttgctgaca atgataaaac tggattccgg
     4981 aatttcaact atgcaaccca atcaaagcgt agtcctggtt ctacaattaa gcctttagtt
     5041 gtttatacgc cagcagttga agcaagctgg gctttgaata agcagttgga taaccatacc
     5101 atgcagtatg acagctataa ggttgataac tatgcaggga tcaaaacgag tcgagaagtt
     5161 cctatgtatc aagccttggc agaatcgctt aatctacctg ctgttgccac tgttaatgat
     5221 ttgggtgtcg acaaggcttt tgaggcaggc gaaaaattcg gactcaacat ggaaaaggtc
     5281 gaccgtgttc ttggtgtcgc cttgggaagc ggtgttgaaa ccaaccctct tcaaatggct
     5341 caagcatacg ccgcctttgc aaatgaaggt ttaatgcctg aagctcattt tattagtaga
     5401 attgaaaatg ctagtggaca agttattgcg agtcataaaa attcacaaaa acgggtgatt
     5461 gataagtctg tagctgacaa gatgaccagt atgatgttgg ggactttcac caacggtacc
     5521 ggtattagtt catcgcctgc agactatgtc atggcaggga aaactggaac aactgaagca
     5581 gttttcaatc cggagtacac aagtgaccag tgggtaattg gttatactcc ggatgtagtg
     5641 attagccact ggcttggctt tccgaccact gatgaaaacc actatctagc tggctctact
     5701 tcaaacggtg cagctcatgt ctttagaaac attgccaata ccattttacc ttatacgcca
     5761 ggaagtacct ttacggttga aaatgcttat aagcaaaatg gaattgcacc agccaataca
     5821 aaaagacaag tacaaaccaa tgataatagc cagacagatg ataatttgtc tgatattcga
     5881 gggcgtgcgc aaagtctagt agatgaggct agccgggcta tctcagatgc gaagattaag
     5941 gaaaaggctc aaacaatatg ggattcgata gtcaatctat ttcgctaaga tgcttgtcaa
     6001 agcctagctt tcttgttata atggataaga tggaggcgtt atggcactaa aaaaagcaag
     6061 cctagcttgt gcggtttgtg gttcgagaaa ctattcaatc aagatcagcg gaaacctcaa
     6121 gcctacacga ctagaagtaa ataaattttg taagcattgt ggcaagtaca ctacacacag
     6181 agaaacgaga taggagagag cgatgcgttt tattggagat atttttagac ttcttaaaga
     6241 cacaacatgg ccaactcgca aggaaagctg gagagatttt cgttctatca tggaatacac
     6301 agctttcttt gtagtaatta tttacatttt tgaccagttg attgtttcag gtttgattcg
     6361 atttattaac attttttaga agattagtgg agttaattac actagaaatc ttctatttat
     6421 gaaaggaaat atcatggata gttttgataa agggtggttt gttttacaaa cttattctgg
     6481 ttatgaaaat aaggtgaaag aaaatctatt acaacgtgca caaacctaca atatgttgga
     6541 taatattcta cgcgttgaaa ttccaacaca aacagtgcaa gttgaaaaaa atggaaagag
     6601 aaaagaagta gaagaaaatc gctttccagg ttatgttctt gtagaaatgg tcatgacaga
     6661 tgaagcttgg tttgttgttc gaaacacacc aaatgttaca ggatttgtcg gatcacacgg
     6721 gaacagatca aaaccaactc cattattgga acaagaaatt cgcgacattt tggtatctat
     6781 gggacaaact gttcaagaat ttgatttcga tgttgagatt ggtcaaactg tacgtattat
     6841 tgatggtgct tttgcagact acactggtaa gattacagaa attgataata acaaagtgaa
     6901 aatgattatc tctatgtttg gtaatgacac agttgcagaa gtaaatctaa accaaatcgc
     6961 agaattataa ccctgagaga ggctggagct tctctttttt gtgcagttta ggagctaaag
     7021 ggaacagaat ggagaaaatg gaacaaatgt gttttctaat ctgttagact gtatctagaa
     7081 aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgtg tataagtgta
     7141 gaaatgaata ttaccttcat ttatgggaat tgtcggattg ggagcaagaa ggcatgctct
     7201 gcttacatga attgattagt agagaagaag gactggtaga cgatattcca cgtttaagga
     7261 aatatttcaa gaccaagttt cgaaatcgaa ttttagacta tatccgtaaa caggaaagtc
     7321 agaagcgtag atacgataaa gaaccctatg aagaagtggg tgagatcagt catcgtataa
     7381 gtgagggggg tctctggcta gatgat
//
LOCUS       DBEROT010000068         7393 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.68, whole genome shotgun sequence.
ACCESSION   DBEROT010000068 DBEROT010000000
VERSION     DBEROT010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.68"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            226..6657
                     /locus_tag="ACL8CG_002032"
     CDS             226..6657
                     /locus_tag="ACL8CG_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS1344567.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            7284..>7393
                     /locus_tag="ACL8CG_002033"
     CDS             7284..>7393
                     /locus_tag="ACL8CG_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HGS1344568.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIV"
BASE COUNT         2909 a          989 c         1420 g         2075 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacattt ctgataaaga aaaagtagta
      361 ttagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca gttattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaaggt
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacactgatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctttaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataacgaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgca gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgacatttg atttatacgc taatattaat gatattgtgg atggattagc ttttgctgga
     4801 gatatgcggt tttttgttaa agatgatgat cgaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaagggaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gttgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcaaggaa ttaagtagcg tttggttgct taattccttt ttatttggaa
     6961 ggaagttttt cgtaaccgcc caataacgaa gtctattggg cggttacgat atgatcactg
     7021 acttcgtcag ttctatctac aacctaaaaa cagtgttttg aacaacctgc ggctagcttc
     7081 ctagtttgct ctttgatttt cattgaatat tagaacagca aaaatgcttg gagtatttgt
     7141 ttgtgtgttt gtttttatat aacaaactat aaacaaaaca aaaatataaa aaaagagaca
     7201 aaaaagaaca aaaagtaatt gacaacggtt tcatatagtg ttatacttat ggcataaagt
     7261 taatggaaag aagggaaaac cttatggtat tagattattt ctttgacaaa aaccttgtgt
     7321 tttgcttaga agcggataat caagaacaac tctttgatca ggttgcaact ttattggaag
     7381 aacgagaaat tgt
//
LOCUS       DBEROT010000069         7113 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.69, whole genome shotgun sequence.
ACCESSION   DBEROT010000069 DBEROT010000000
VERSION     DBEROT010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7113
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.69"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..900)
                     /gene="phtA"
                     /locus_tag="ACL8CG_002034"
     CDS             complement(<1..900)
                     /gene="phtA"
                     /locus_tag="ACL8CG_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGS1344569.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QYREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLS"
     gene            complement(1154..2887)
                     /gene="ptsP"
                     /locus_tag="ACL8CG_002035"
     CDS             complement(1154..2887)
                     /gene="ptsP"
                     /locus_tag="ACL8CG_002035"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGS1344570.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(2893..3156)
                     /locus_tag="ACL8CG_002036"
     CDS             complement(2893..3156)
                     /locus_tag="ACL8CG_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGS1344571.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            3507..3725
                     /gene="nrdH"
                     /locus_tag="ACL8CG_002037"
     CDS             3507..3725
                     /gene="nrdH"
                     /locus_tag="ACL8CG_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGS1344572.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            3806..5965
                     /gene="nrdE"
                     /locus_tag="ACL8CG_002038"
     CDS             3806..5965
                     /gene="nrdE"
                     /locus_tag="ACL8CG_002038"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGS1344573.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6153..>7113
                     /gene="nrdF"
                     /locus_tag="ACL8CG_002039"
     CDS             6153..>7113
                     /gene="nrdF"
                     /locus_tag="ACL8CG_002039"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGS1344574.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNCGLD"
BASE COUNT         2062 a         1522 c         1329 g         2200 t
ORIGIN      
        1 actcaaaggc agtttgtaga gctgtttcaa gagactatca atgtcattac tttgacttgc
       61 ttgactgtta gtgttgctgt tgttgcttgt gttagtattt gtagttcctg gattgcttac
      121 agaaggtacc cagtttgttc ttgaagtgtt atcgctattt tgtcggcgat aggttcttga
      181 atttgacaga tttccccgac cagataggaa ggcttctgca gcagctaact cgctagctga
      241 taactcattc ttaggaatgt aatggtaatg gtcgccgtga ggaacgatat aagcatcacc
      301 agtatcctct atgatatcag aagcattaaa gatataacca tcatctgtag tatagcgtcc
      361 ttgcgaacgt gccaaggcaa cagctccatc gtttcttgga gtccctcctt cacgatactg
      421 actatgttct tgtttttgtc gattgatttc ctcttttgta cggacgttat ccgcgtgggc
      481 agcatcctta aggtaaacat agtattttcc atctaccttg ataacatatc cacccttgac
      541 ctcattaaca atatcctcat cttttagctt atagtttgga tctttcatga gtaattcttc
      601 actgaaaatc gcatcataag gaaccttacc attgtaataa tgatagtggt cgccatgtga
      661 agtgacatag ccttggtctg ttatcttgat gacgatttgc tcagcattga ttccttcacg
      721 cttgctaacc tcatcaggag tcaaattctc cgttttttgc gtcgcttgtt ttccatctat
      781 ataggaaaca cgattatttt ccttaaccgt tctagcttga tacagtccca actcgtaaga
      841 acaaacactt aaaatcaaag ctgccgcaga accaacaagg tatttcttat taattttcat
      901 cgaaactctc tttctatttg atatttctag ttgcaattca tttctaaatt gcagaaactc
      961 ctctctatta cttaactggt taatagttta ctcctaaatc tccaacttgt caagaatttt
     1021 atgaaccatt taagtatttt ttgttctgac cactactttt tcaaggttgg actttctata
     1081 aaaaagattt tcttgaaaat tctttttaaa atatcaaaaa aatccctgta actgagttgc
     1141 agggacttgt cgattaatca aaattaacgt attctttttg aagttcaaga acttcttcca
     1201 ttgttgagca ttctgtaagg gcacggtttg cgtactcttc catcttagct gtgtcgagtt
     1261 tcttcatcaa gctgcgtgta cgaagtacag atgttgctga catagagaac tcatccaagc
     1321 ccattccgac aagaagtgga acagcttgtt ggtcaccagc catctcacca cacataccag
     1381 cccatttacc ttcagcgtga gctgctttga tcacattgtt aatcaagcgt aggattgatg
     1441 ggttgtatgg ttggtaaagg tatgaaactt gttcgttcat acggtctgct gccattgtat
     1501 attggatcaa gtcgtttgta ccaattgaga agaagtcaac ttctttagca aattggtctg
     1561 caagcatagc cgctgcagga atctcaatca tgataccaac ttggatgtta tccgcaactg
     1621 caacaccttc agcaagaagg tttgcttttt cttcatcaaa gactgctttc gctgcacgga
     1681 attctttcaa gagcgcaacc attgggaaca tgatacgcaa ttgaccgtga acagacgcac
     1741 gaagaagagc acggatttgt gtgcggaaca tagcatctcc agtctcagag atagagatac
     1801 gaagagcacg gaatccaagg aatgggttca tttcgtgagg catatcgaag taaggaagtt
     1861 ccttatctcc accgatatcc attgtacgaa cgacaacagg tttaccgttc attccttcaa
     1921 gaacagcctt gtatgcttca tactgctcat cttcagttgg gaagtcttga gaatccatgt
     1981 acaagaactc tgtacggtaa agtccaacag cttctgcacc gttgttgtta acaccttcaa
     2041 cgtcttttgg agtaccaata ttggcagcca actcgaagtg tttaccgtca gcagtcactg
     2101 tttgagcatc tttcaaaagt gcccattcag ctttttgttt cgcataggct tcaccagctg
     2161 ctttaaattc tgccgcttgt tcatctgttg ggttgataat cacttctcca gtgatcccgt
     2221 taacagcaag gatgtcaccg tctttaacga tttcagtgat gttatttgta cctaatacag
     2281 cagcaatttc aagtgtacgt gccatgatag ctgagtggct tgtacgtcca ccaatgttgg
     2341 ttacaaaagc ttttacaaag tttttgtcca attgagctgt atctgaagga gtcaagtcat
     2401 gcgcaatcac aatcacttct tcattgatag aagctgggtt tggcaatttt ttaccaagaa
     2461 ggtttgccaa tacacgtttt gtcacgtcgc ggatatccgc tgcgcgttct tgcatgtatg
     2521 ggttgtcttc catgccttca aagatagtga taaacatatc tgtaacttct ttcagacctg
     2581 cttctgcatt cactttcttc gcacggatag tttccttgat ttggctgatc atttctgggt
     2641 cagcaagaac cattaagtga gcatcaaaaa cttgagctgc ttcttcaccg agcgtaccta
     2701 ctgctttctc gcgaataaca gaaagctcgt cttgtgatgc ctgtagagcg gcatcaaggc
     2761 gagcttcttc tgcgtttgta tcttcgactg taatagtctc aaatgacaaa tccggctgaa
     2821 cgagtagata tgcttttgca actgcaacac cgtcagatgc tgcgattcct ttaagcattt
     2881 ctgtcatttc ccttatgcca atccttcttt ttccattgtt tctgagattg cagcgatagc
     2941 gtcatctgca tctgcacctt cagctgagat agttacgtca gcaccttgac caacaccaag
     3001 actcataaca cccataattg atttaaggtt aactgattta cctttgtact caagagtgat
     3061 atctgaagca aatttgctag cagtttgtac caacaatgtt gctggacgtg cgtgaatacc
     3121 tgtttctgcc actacgtgga aatctttaga agccatagtt tgactctcct tttgttcttt
     3181 ctttttttga gttatatgtg ataaccctta caatttagta ttataccatc ttctaggatt
     3241 tttttcaagc attttctgga ttttccttca atttcctttc agataacttg ctgaaaatct
     3301 tctatcctag ataacaaaac acaggatata gtttcttcaa aaacaattta taggataatc
     3361 attgctattt cacaatacaa acactatata ttgtgtttat atataaaaac aacaaaagaa
     3421 caccactata tttagtttaa atcattgaca aaattttatt ttctgatata ctaagatagt
     3481 attaaatttt gaagaggagt tacacaatgg taaccgttta ttctaaaaac aattgtgtcc
     3541 aatgtaaaat gaccaagcgt ttcttggaca gtaataatgt ctcttatcgt gaaatcaatc
     3601 ttgatgagca acctgagtac gtcgatcaag ttaaagagct cggttttagc gcagctcctg
     3661 ttatccaaac accaactgaa gtcttttcag gtttccaacc aggaaaactg aaacaattag
     3721 cataatctta gtacatcatc cagaagaaac tgcttttagg gctaacttag aagcctttct
     3781 tttgtaatta gataagggaa attttatggg attaaaacat cttgaagacg tgacttactt
     3841 ccgtcttaat aacgaaatta accgtcctgt taatggacaa atcatgcttc ataaagataa
     3901 ggaagccttg gatgctttct ttaaagaaaa tgtagttcca aacactatgg tttttgattc
     3961 aatcaaagac aaaatcaatt acctcattga acacaactac atcgaaacag cctttatcaa
     4021 gaaataccgt ccagagttct tggaagaatt ggctcaattt atcaaagacc aaaacttcca
     4081 attcaagtca ttcatggcag cttataaatt ttacaatcaa tatgccttaa agactaatga
     4141 cggtgaatac tatcttgaaa atatggaaga ccgtgtcttc ttcaacgccc tttatttcgc
     4201 tgatgggaat gaagctgttg caatcgatat tgccaatgaa atcatccacc aacgctacca
     4261 acctgctact ccttccttct tgaatgctgg acgtgctcgt cgtggggagt tggtatcttg
     4321 tttcctaatc caagtgacgg atgatatgaa ctctatcggg cgttctatca actcagctct
     4381 tcaactttca cgtattggtg gtggtgtggg aattaccctc agcaaccttc gtgaagctgg
     4441 tgcacctatc aaaggctatg aaggagctgc ttcaggtgtc gttcctgtta tgaagctttt
     4501 tgaagacagc ttctcttact ccaaccaatt ggggcaacgt caaggtgccg gcgttgtcta
     4561 cctcaacgtc tttcacccag atatcatcgc tttcctttca actaagaaag aaaacgctga
     4621 tgaaaaagta cgtgtcaaga ctctatcact tggtgttgta gtacctgata aattctacga
     4681 attggctcgt aaaaatgaag aaatgtacct cttcagccct tactctgtag aaaaagaata
     4741 cggtgtgcca ttcaattaca tcgacattac tgaaaaatac gatgaattgg tcgcaaatcc
     4801 aaatattcgc aagacaaaaa tcaaggcgcg ggatttggaa actgaaatct ctaaattgca
     4861 acaagagtct ggctatcctt atgtagtcaa catcgatacg gctaaccgtg caaatcctgt
     4921 tgatggaaag attatcatga gtaacttgtg ttctgagatt cttcaagttc aagaaccaag
     4981 cttgatcaac gatgctcaag aattccttca aatgggaaca gatgtttcat gtaacctggg
     5041 ttcaaccaac gtggttaaca tgatgacttc acctgatttt ggtcgttcta tccgtgctat
     5101 ggttcgtgcc cttactttcg ttacagatag ttcacatatc gtagctgtac caacgattga
     5161 ccatggaaat agccaagccc acacctttgg tctcggtgcc atgggactgc acagctacct
     5221 tgcccaacaa ctcattgaat atggttcacc tgagtctgtt gaatttacaa gcatctactt
     5281 tatgcttatg aactactgga ccttggtaga gtcaaacaat attgcacgtg aacgtggtat
     5341 taccttccac aactttgaaa aatcagacta tgctaacgga agttactttg acaagtatgt
     5401 aactggtgaa tttgttccaa catcagaccg tgttaaagaa ctcttcaaaa atgtttttat
     5461 ccctggtgtt gctgattggg ctgaacttcg cgacaaggtt caagaagatg gtctttacca
     5521 ccaaaatcgc cttgctgtag cgccaaatgg ttctatcagc tatatcaacg acgtttctgc
     5581 ttctatccac ccgattacgc aacgtatcga agaacgccaa gagaagaaaa ttggtaaaat
     5641 ctactaccct gctgctggct tgtctacaga aaccattcct tactacactt ctgcctacga
     5701 tatggatatg cgtaaagtca tcgatgttta cgctgctgcg actgaacacg tggatcaagg
     5761 actttcactc accctcttca tgcgcagtga cattccaaaa ggcctttacg aatggaagag
     5821 ggaaaataaa caaacgacac gtgatttgtc catccttcgt aactatgcct ttaacaaggg
     5881 aatcaagtct atctactacg tccgtacctt tacagatgac ggtggagaag tcggcgccaa
     5941 ccaatgtgaa agctgtgtga tttagtttct agcatagaaa cattattttt ccctaagcag
     6001 cactgataaa atcaaatcta ctatgtcata atataattta tgtaacattt taaaagtcgg
     6061 gcttccgact ttttgtgcga tactcctata gaattatggt aaagtagaaa taattgtgag
     6121 ttcgcaatac taaacacaga aagagatttt aaatggaaac ttactacaaa gccattaact
     6181 ggaatgccat cgaagatgtc atcgacaaat caacttggga aaaactgacg gagcaatttt
     6241 ggctcgatac acgtattccc ttatcaaacg acttggatga ctggagaaag ctatctaaca
     6301 aagagaaaga cttggtcgga aaagtttttg gtggtttaac ccttcttgac actatgcaat
     6361 ctgaaactgg ggttcaagcc cttcgcgcag acatccgtac accacatgag gaagctgttt
     6421 tcaataacat ccaatttatg gaatctgtcc acgctaaatc ttactcatca atcttttcta
     6481 ccttgaatac taaggctgag attgaagaaa ttttcgaatg gaccaatacc aatccttacc
     6541 tacaaaagaa ggctgagatt gtcaacgaaa tctacctaaa cggcagccca cttgaaaaga
     6601 aagttgccag cgtcttcctc gaaaccttcc tcttctactc tggtttcttc actcccctct
     6661 actatctcgg taacaacaaa ctagccaacg ttgcagaaat cattaaattg attattcgtg
     6721 acgagtctgt tcacggaacc tacattggtt acaaattcca acttggtttc aatgaattgc
     6781 ctgaagaaga gcaagaaaaa ctcaaagaat ggatgtacga cctactctat actctttatg
     6841 aaaatgaaga aggctacaca gagagtcttt atgacggtgt tggttggact gaagaggtta
     6901 aaaccttcct tcgctacaat gccaataaag ctctcatgaa catgggacaa gatccacttt
     6961 tcccagattc agctgaagat gtcaacccaa tcgttatgaa cggtatttca acaggaactt
     7021 ccaaccatga cttcttctct caagtcggaa atggttacct tcttggcgaa gttgaagcca
     7081 tgcaagatga tgactacaac tgcggtttgg act
//
LOCUS       DBEROT010000070         7044 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.70, whole genome shotgun sequence.
ACCESSION   DBEROT010000070 DBEROT010000000
VERSION     DBEROT010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.70"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(147..2144)
                     /gene="metG"
                     /locus_tag="ACL8CG_002040"
     CDS             complement(147..2144)
                     /gene="metG"
                     /locus_tag="ACL8CG_002040"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGS1344575.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2268..3527)
                     /locus_tag="ACL8CG_002041"
     CDS             complement(2268..3527)
                     /locus_tag="ACL8CG_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344576.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3529..4230)
                     /locus_tag="ACL8CG_002042"
     CDS             complement(3529..4230)
                     /locus_tag="ACL8CG_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1344577.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4214..5413)
                     /locus_tag="ACL8CG_002043"
     CDS             complement(4214..5413)
                     /locus_tag="ACL8CG_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGS1344578.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVILGAGGILLFRQPSQTALKDE
                     PIHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5678..7024
                     /gene="gor"
                     /locus_tag="ACL8CG_002044"
     CDS             5678..7024
                     /gene="gor"
                     /locus_tag="ACL8CG_002044"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGS1344579.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         2033 a         1565 c         1340 g         2106 t
ORIGIN      
        1 catgttttga gctgacttcg tcagtttcgt ctacaacctc aaaacagtgt tttgagcaac
       61 ctgcggctag cttcctagtt tgctctttga ttttcattga gtataaataa aaaaacagaa
      121 ctagcctgaa ctagtcctgt ctacttttac ccaatcacac ttccatttgg tacagctgga
      181 tcaactgtga gaagggttaa tttgccatca tgttcagctg agagaatcat accctggctg
      241 acatattttt tcatcatttt acgtggtttg aggttagcaa cgatttgaac tttcttgccg
      301 accaattctt gttcatttgg atagtatttt gcaattcctg aaagaatctg acgatcttct
      361 ccatcaccag catccaagcg gaattgaagc aacttatctg aaccttctac tttagacact
      421 tctttgactt ctgcgacacg gatttcaacc ttgtcaaagt cttcaaactt gatttcatcc
      481 ttgtttagtt tgagctcaac ttcgtccgga ttccattctt tttcgactgc tggtttattg
      541 ccttccattt gttccttgat ataggcgatt tcttcttcca tatttagacg tggaaagata
      601 ggtgttcctt tggcaactac agtcacatct gctgggaagt cagccaaact caagttttca
      661 agactagaaa cttcttccaa accaagttga gtcaaaactg cacgactagt ttccatcata
      721 aatggttcaa tcaagtgagc aactacacga atgctggctg ccaagtggct catgacactt
      781 gccaattggt cacgaagagc ttcatccttg gccaagaccc atggtgcggt ctcatcgatg
      841 tatttattgg tacgagagat cagagtccag actgcttcaa gcgcacgtgg atagtcaact
      901 gcttccatgt gtgtatggaa gtctgcgatt gattgttctg caacctcagc aagaacatga
      961 tcaaattcag tcacaccttc tacataggca gggatttgtc catcaaagta cttattaatc
     1021 atggaaaccg tacggttaag gaggttccca aggtcattag ccaattcata gttgatacgg
     1081 ccgacatagt cttcaggagt aaaggttccg tctgaaccaa ctggaaggtt acgcatgagg
     1141 tagtaacgaa gtggatctag tccataacgc tctaccaaca tttcagggta aacgacattc
     1201 ccttttgact tagacatttt tccgtctttc atgacaaacc aaccatgggc aatcaaacga
     1261 tcaggtaatt taacatccaa catcataaga aggattggcc agtagataga gtggaagcga
     1321 aggatatctt ttcctaccat atggaagact gttccattcc agaacttgtc aaagttacca
     1381 tgttcgtctt gagcgtagcc aagagctgtc gcatagttaa gaagggcatc aatccaaacg
     1441 tagacaacgt gttttggatt tgatgggaca ggcactcccc atgtaaaggt tgtacgagat
     1501 accgccaaat cttccaagcc tggctcgatg aagttgcgta gcatttcatt aaggcgacca
     1561 tctggcgtga taaattcagg atgagctttg aaaaattcga ccaaacggtc ttggtatttg
     1621 ctaaggcgaa ggaagtatga ttcttcagaa acccattcaa cctcatgacc tgatggagca
     1681 ataccaccag tcacatttcc agcttcatca cggaaaactt ctgccagctg gctttctgta
     1741 aagaattctt cgtctgatac tgaataccaa ccagagtatt cacccaagta gatatcatct
     1801 tgagcaagta agcgttcaaa gacttgtgcg acaacttttt catggtagtc atcagttgta
     1861 cggataaatt tatcgtatga gatatctagt aattgccaga gttctttaac tccaaccgcc
     1921 attccatcaa cataggcttg aggtgtaata ccagcttctt ccgctttctg ctggattttc
     1981 tgaccatgtt catcaagacc tgtcagataa aatacatcgt agcccatcag gcgtttgtaa
     2041 cgtgctagga catcacatgc gatagttgtg taggcagaac cgatatgaag tttcccagat
     2101 ggatagtaaa tcggcgttgt aatataaaaa tttttttcag acataatttt tcctttccag
     2161 gcaaatgaaa cctgtttttc taacacttca ttatatcaca tttttaatga atttcaatag
     2221 ggaaatccat acaaaaacaa gatagacgag tgtccatctt gttgatctca ttcataacga
     2281 agggcttcaa ttggatcaag tttcgatgcc ttgttggctg gcaagactcc aaaaatcata
     2341 ccaacactag ccgaaactgc aagactaaat agggcgactg ggattgatac tccaacttct
     2401 ataccttcta ttaaaccttg cagtaacaaa cctgctaagg cagttaaacc acttgcaatt
     2461 gtcaagccaa ttaagccacc taacaaggtc aaaatcatgg attcaatcaa aaactgaatt
     2521 aaaatattgg cacgtgttgc acccaaagcc ttacgaagac caatctcacg agtgcgctct
     2581 gtcaccgaaa ccagcatgat gttcatgaca ccagttcctc caacaaagag agaaatccct
     2641 gcgatggaac taataatcgt cgtcataaaa ctaaacgatt gttgaatttc tgcaaataca
     2701 acggactcat ctgccacctg gtattctccc tgttgtaagc ctgcaagctc tgtcattttt
     2761 cgtgccagtt ctggacccag agttggggtt aaactggtat cattcactcg aaagacaata
     2821 ttagctattt catctacatt aaaattcgca gcaagggaga tattggtagt aataggcaag
     2881 ccaccaaacc catatatttt tgatctttta gcctccggac tagtataaac cccaatgacc
     2941 cggtaactaa atccattgac ttctacaacc ttgttaatag cctcttgagg agattcaaat
     3001 aaactaatgg acaattcctc atctagcaaa atgacacttg caaactcttt gaaatcttgc
     3061 tctctcagac tacgacctgc aataatttca ttcttaacag cgtccatgta agttctgttt
     3121 ccacctgtca aattagcatt ctcaaccttt ttatcttgat aggtcaagat ggcattcgtt
     3181 gaattggtta catagtaact atccactccc ttcagtttag ctgcctcttg aacccaggat
     3241 tcttgcggtt ttggcggttc aacaggaact tcctcttcct ttccagaaac cgtaaaagct
     3301 gattgtttct gagtaaaaga cccgtcttta ctttttttag gagaaaaaaa gacgctaata
     3361 tttttctgag atttagtcat atctttattg acttgacgag atagggaatc acccaaagcc
     3421 ataatcacaa caactgatga aacaccgata ataatcccaa tcatagtaag caaagaacgc
     3481 atcttgtgag ccatgataga tgaaaaggca aatttcagat tctgcatctt agttttcctc
     3541 ctttcctaac tgagcactgt cagacgaaat gaccccatcc cgaatgacaa tctgacgttt
     3601 ggcataggca gcaatctcag gctcatgcgt taccatgata atggtttttc cttctttatt
     3661 caaatcaacc aataattgca taatttggtt acctgttttg gtatccaagg ctcctgtcgg
     3721 ttcatccgct aggataatag aaggattgtt taccaaggca cgcgcaatgg ctacacgttg
     3781 cttttgacca ccagataatt ctgaaggtaa atggtgacta cgttctgtca attcaacctt
     3841 gtctaaatat tcctcagcca acttgcgacg ttttgaagac gaaactcctg cgtaaatcaa
     3901 gggcaattct acattttgca gagcattgag cttcgataga agaaagaact gctgaaagac
     3961 aaaaccgatt tgttggttac ggaccttagc tagttgtttt tcaccaagcc cagccacttc
     4021 ttgaccttca agataatatt ctccactggt tggtgtatcc aacatgccaa tcgtattcat
     4081 cagagtggac ttaccagacc cagatggtcc catgatggct acaaattcac cctcattcac
     4141 ttctagattg atatttttga gaacctgcag ttcttggtca ccattacggt aacttctgaa
     4201 gatatttttt agactaatta gttgcttcat cagccttcac ctcttttcct tcttccaagg
     4261 aagatgttgg attactgatg accttagcac cgttcgttaa accagaagtg atttcttgat
     4321 tttctgcgtc agcatttccc aatgaaacct caactttttt agccttttgt tgttcatcca
     4381 caatccagac ataattttta ctatcatcca ttactagact gctaacagga acaagaatag
     4441 ccttagtttt gcttttaacc tcaatgttga cagaaaaacc ttgtttcaaa tcaccaacct
     4501 cgcctgtcac atcaatagta taagggtatt tagaacctgt attattcccg gctgctggac
     4561 tagctgcttc accattgttt ttaggatagt cagaaatata gcttaatttc ccagtccatt
     4621 ttttatcagg atacacttta gaagtaaagc ttacttcttg acctacagaa aggttggcta
     4681 gattgtactc agacaattct cccttgactt gtaaattttc attgctgaca atatgaacca
     4741 taacttggct cgcccctgtt ggagatttag aaacattgct attgacttcg actacagttc
     4801 cctctagggt actgagaaca gttgttgcat ccaattgact ttgagccttg cttaattgcg
     4861 ccgcagcatc tgcacgcgca tcacgggcat cacccaattg agcgtcaata gaagcaacag
     4921 aatttccagc cactggagtt gggctttgca ccgttgcatc ttctcctcct actggcgctg
     4981 gtaactgtgg agccggagct gaagcggctt catttcgtgc ttgattgagt tcattgatat
     5041 gacgatctgc cctagctact gctcgactag ctgaatcata ggccgcctgc gcttctgaac
     5101 tactgtactt gactaaagcc tgcccttcgc tgaccttatc gcccacagaa acaaggattt
     5161 catctaaatc acccttacta gcatcaaaat aaacatattg ttcatttttt gctgttactg
     5221 tccctgacaa taaaacagag gaggccacgc ttccttcctt ggcaacaaca agatgaatag
     5281 gctcatcttt tagagcagtc tgagaaggtt gtctaaagag taaaatcccc ccagcaccca
     5341 atataactac actcgcagca ccgattgctg catacagttg ccacttttta gctttaccat
     5401 tctttttctt cataatgaaa ctccttttct tttttacaat actttgctat tataccaaat
     5461 ttccctccag caaacaatac agttcaggat taaacaatcg ttcggaattt tgcttttcta
     5521 ttgtactaga tatatgatac actatcttga cttatttggc aagctttttt gcaatttttt
     5581 gtgcgtagca gatttttgca atcaaatcaa aaaaagaata aaatataact atcaaaaaag
     5641 acgctctact atttaaaaga ttacaaagga gttttcaatg agagaatatg atatcattgc
     5701 tatcggtgga ggtagcggag gaatcgctac catgaaccgt gctggtgaac atggagccaa
     5761 agcagccgtt attgaggaaa agaaattagg tggaacctgt gtcaacgtcg gttgtgttcc
     5821 taaaaaaatc atgtggtacg gggcgcaaat cgctgagact ttccatcaat ttggagaaga
     5881 ctacggcttt aagactactg atcttaactt tgactttgca accctacgtc gcaatcgtga
     5941 agcctacatt gatcgcgctc gttcttctta tgatggtagt tttaaacgca acggtgtaga
     6001 cttgattgaa ggtcatgctg aatttgtaga ttctcatact gtaagcgtaa atggtgaact
     6061 gattcgtgct aaacatatcg tgattgctac aggtgcccat ccaagtattc ctaatattcc
     6121 tggtgctgag ctaggtggct cttctgatga tgtatttgcc tgggaagaac ttccagagtc
     6181 agttgccatt ctaggtgctg gttatatcgc cgttgaatta gctggcgtac tccacacttt
     6241 tggtgtcaag acagatctct ttgttcgccg cgatcgtcct ttacgtggtt ttgattccta
     6301 catcgttgaa ggtttggtca aggaaatgga aagaataaac ttgccacttc atactcacaa
     6361 agtccctgcc aagttagaaa aaactgctaa aggcattacc attcatttcg aggatggtac
     6421 cagtcacaca gctagccaag ttatctgggc tacaggtcgc cgtccaaacg ttaagagctt
     6481 gcaacttgaa aaagctggag tgactctgaa tgaacgtggc tttatccaag tagatgaata
     6541 ccaaaatact gttgttgagg gaatctatgc tctaggtgat gtaacaggtg aaaaagaact
     6601 gactccagtt gcaatcaagg ccggacgtac cctatctgaa cgtctcttta acggaaaaac
     6661 tactgcaaaa atggattact caactattcc aactgttgtc ttttcacacc ctgctatcgg
     6721 aactgttggt ttgacagaag agcaagctat taaagaatac ggtcaagacc aaatcaaggt
     6781 ttataaatca agctttgcat ctatgtactc tgcttgcact cgcaaccgtc aagaatcccg
     6841 tttcaaactc ataacagctg gttcagaaga aaaagttgtc ggacttcatg gaattggcta
     6901 cggcgttgat gaaatgattc agggatttgc cgttgctatc aaaatgggag caaccaaggc
     6961 tgactttgat gcaactgtgg caattcaccc aactgcatct gaagaatttg taaccatgcg
     7021 ttaatcgaaa caaaagaagc tgat
//
LOCUS       DBEROT010000071         6416 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.71, whole genome shotgun sequence.
ACCESSION   DBEROT010000071 DBEROT010000000
VERSION     DBEROT010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.71"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(93..389)
                     /locus_tag="ACL8CG_002045"
     CDS             complement(93..389)
                     /locus_tag="ACL8CG_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS1344580.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(379..561)
                     /locus_tag="ACL8CG_002046"
                     /pseudo
     CDS             complement(379..561)
                     /locus_tag="ACL8CG_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
     gene            610..1374
                     /locus_tag="ACL8CG_002047"
     CDS             610..1374
                     /locus_tag="ACL8CG_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGS1344581.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(1614..1766)
                     /locus_tag="ACL8CG_002048"
     CDS             complement(1614..1766)
                     /locus_tag="ACL8CG_002048"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344582.1"
                     /translation="MKIKASIRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NISTAR"
     gene            1984..3363
                     /locus_tag="ACL8CG_002049"
     CDS             1984..3363
                     /locus_tag="ACL8CG_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS1344583.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3377..4042
                     /locus_tag="ACL8CG_002050"
     CDS             3377..4042
                     /locus_tag="ACL8CG_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGS1344584.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4177..4335
                     /locus_tag="ACL8CG_002051"
     CDS             4177..4335
                     /locus_tag="ACL8CG_002051"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344585.1"
                     /translation="MKIKDQTRKLATGCSKQCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            4397..4936
                     /locus_tag="ACL8CG_002052"
     CDS             4397..4936
                     /locus_tag="ACL8CG_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1344586.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            5036..5413
                     /locus_tag="ACL8CG_002053"
     CDS             5036..5413
                     /locus_tag="ACL8CG_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGS1344587.1"
                     /translation="MIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLDLSQVSHPKMRE
                     YLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPKVFQAIRKTMLSRLTKH
                     SVLPDRKLSNVVYQITKSVYGFN"
     gene            5529..>6416
                     /gene="pavB"
                     /locus_tag="ACL8CG_002054"
     CDS             5529..>6416
                     /gene="pavB"
                     /locus_tag="ACL8CG_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGS1344588.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLV"
BASE COUNT         1733 a         1224 c         1485 g         1974 t
ORIGIN      
        1 gcctgcggct aacttcctag tttgcacttt aattttcatt gagtattact tcatcttctc
       61 atgaaattga gtttttgccc agctcctctt gattattcta cttgaccggg ccaagcattc
      121 ataccacctt ctacgttggt aacggtgagg ccttgggagc tgagaaattg gcaggtagat
      181 gcagagcgga ctcctccttg acaaatgaca tagtattcat ggtcaggttt gagttctttg
      241 tagccttgct ctaaggtact taatggaaga tttttggcac ctggtgcatg tcctgcttgg
      301 aattcatgtg cttcacggac atcgataagt tctagatttt cattttggta ttttccataa
      361 aagtcagcca tgctgatact agtttccata ttctactcct tctgggttaa ccattttgta
      421 tagtgaataa gcgccgtcaa ggttttgggc ggtaaatcct gcttgcttga ggataggctc
      481 tgcgatatag ctgcgcaaac cactgtggca gctgacgatg taggcttgtt ttttgtccag
      541 ttcatcagct tcctccttga cactttgtca gtttttgata caatagtaca aaattagagg
      601 aggcaggcta tgattcagaa acatgcgatt cctattttag agtttgatga caatcctcag
      661 gcggttatca tgcccaatca cgaggggctg gacttgcagt tgccaaagaa gtgtgtttat
      721 gcatttttag gtgaggagat tgaccgctat gcaagggaag taggggcgga ttgtgtcggc
      781 gaattcgttt ctgctaccaa gacctatcca gtctatgtca tcaactacaa gggtgaggag
      841 gtctgtctgg ctcaggctcc tgttggctcc gctccagcag cccagtttat ggattggttg
      901 attggctatg gtgtggagca gattatctct actgggacct gtggtgtcct agctgatata
      961 gaggaaaatg cctttctagt ccctgttcgc gctttgcgag atgagggagc cagttaccac
     1021 tatgtggcac cttgtcgtta tatggaaatg cagccagagg ctattgctgc tattgaggaa
     1081 gttttggaag acagagggat tccttatgaa gaagtcatga cctggacgac agacggtttt
     1141 taccgagaaa cggctgaaaa ggtggcttat cgtaaggaag aaggctgtgc tgttgtggag
     1201 atggagtgtt ctgctcttgc ggcagtagct caattgcgtg gggttctctg gggtgaattg
     1261 ttgttcacag cagattctct agcggacttg gaccagtacg acagtcgtga ctggggctcg
     1321 gaagctttta ataaggcgct agaactgagt ttagcaagtg ttcaccacct ttagttgtac
     1381 tggcaaagga tttgttttat cataaaatgt ctagctcata cttttcaaaa atatgtttaa
     1441 acgaggtcac cttcctcttg tcctaggcat gttgaggttg ggaaaaatct ttaaaatcag
     1501 aaaaacgtat catatcaggt gatgaaaact ttgatactat gcgttttatg ttggtaagat
     1561 ttagagtgag atgaaatgat actcttcgaa aatcttttca aaccaggtca gcttcacctt
     1621 gccgtagata tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttgag
     1681 ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgtgactagc
     1741 tttctaatcg atgccttgat tttcattgcc tataatcaaa aagagaaatt ttctcctgaa
     1801 aagcatatag agtagctggc gttaaaagct cctgtcttgc ttttttgacc tatagtcaca
     1861 tctatcaagt attgttcttg cctaagctat caataaaaag gtggcatttt ttaggcttgg
     1921 tgttagtgaa ttttgcctta tcctatctaa gtcatttcga gctttttatg gtacaatgga
     1981 aacatgttat tcaaattatc taaggaaaaa atagagctag gcttatctcg tttatcgcca
     2041 gcccgtcgta tttttttgag ttttgccttg gtcattttac taggctctct tcttttgagc
     2101 ttgccctttg tccaagttga aagctcacga gcgacttatt ttgatcatct tttcactgct
     2161 gtctctgcag tctgtgtgac aggtctctca acccttccag tagctcacac ctataatatc
     2221 tggggccaaa taatctgttt gctcttgatt cagatcggtg gtctagggct catgactttt
     2281 attggggttt tctatatcca gagcaagcaa aagcttagtc ttcgtagccg tgcaactatt
     2341 caggatagtt ttagttatgg agaaactcga tctttgagaa agtttgtcta ttctattttt
     2401 ctcacgacct ttttggttga gagcttggga gctattttgc ttagttttcg ccttattcct
     2461 caacttggct ggggacgtgg tctttttagt tccatttttc tagcgatctc agccttctgt
     2521 aatgccggtt ttgataattt agggagcacc agtttatttg cttttcagac cgatttactg
     2581 gtcaatctgg tgattgcagg cttgattatt acaggcggcc ttggttttat ggtctggttt
     2641 gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc tgcactttca tacgaagctt
     2701 gtactattat tgactatagg tttgttgtta tttggaacag caactactct ctttcttgag
     2761 tggaacaatg ctggaacgat tggcaatctc cctgttgccg ataaggtttt agttagcttt
     2821 tttcaaacag tgacgatgcg aacagctggc ttttctacga tagattatac tcaggctcat
     2881 cctgtgactc ttttgattta tatcttacag atgtttctag gtggggcacc tggaggaaca
     2941 gctgggggac tcaagattac gacatttttt gtcctcttgg tctttgcacg aagtgagctt
     3001 ctaggcttgc ctcatgccaa tgttgcgaga cgaacgatcg cgccgcgaac ggttcaaaaa
     3061 tcctttagtg tctttattat ctttttgatg agcttcttga taggattgat tctgctaggg
     3121 ataacagcca aaggcaatcc tccctttatc cacctcgtat ttgaaaccat ttcagctctt
     3181 agtacagttg gtgtaacggc aaatctgact cctgaccttg ggaaattggc tctcagtgtt
     3241 atcatgccac ttatgtttat gggacgaatt ggtcccttga ccttgtttgt tagcttggca
     3301 gattaccatc cagaaaagaa agatatgatt cactatatga aagcagatat tagtattggt
     3361 taagaaagga aagagcatgt cagatcgtac gattggaatt ttgggcttgg gaatttttgg
     3421 gagcagtgtc ctagctgccc tagccaagca ggatatgaat attatcgcta ttgatgacca
     3481 cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt ggagtgattg gtgacatcac
     3541 agatgaagaa ttattgagat cagcagggat tgatacctgc gataccgttg tagtcgcgac
     3601 aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac tgtaagagtt tgggggtacc
     3661 gactgttatt gctaaggtca aaagtcagac cgctaagaaa gtgctagaaa agattggagc
     3721 tgactcggtt atctcgccag agtatgaaat ggggcagtct ctagcacaga ccattctttt
     3781 ccataatagt gttgatgtct ttcagttgga taaaaatgtg tctatcgtgg agatgaaaat
     3841 tcctcagtct tgggcaggtc aaagtctgag taaattagac ctccgtggca aatacaatct
     3901 gaatattttg ggtttccgag agcaggaaaa ttccccattg gatgttgaat ttggaccaga
     3961 tgacctcttg aaagcagata cctatatttt ggcagtcatc aacaaccagt atttggatac
     4021 cctagtagca ttgaattcgt aaagagggat gacccctctt ttttgatgcc caagatggca
     4081 aatagagaca gaagcccctt gtcttctagt aaaagttctt caaaggctgg actttatggt
     4141 aaaatagaaa gaagtgacaa gagagagtaa tactcaatga aaatcaaaga tcaaactagg
     4201 aaactagcta cgggctgctc aaaacagtgt tttgaggttg tggatagaac tgacgaagtc
     4261 agctcaaaac actgttttga ggttgcagat agaactgacg aagtcagtaa catctatacg
     4321 gcaaggcgac gttgacgcgg tttgaagaga ttttcgaaga gtataagaaa aaatcagtcc
     4381 cctaaaggag cagattatga agttattgtc tatcgccatt tctagctata atgcagcagc
     4441 ctatcttcat tactgtgtgg agtcgctagt gattggtggt gagcaagttg ggattttgat
     4501 tatcaatgac gggtctcagg atcagactca ggaaatcgct gagtgtttag ctagcaagta
     4561 tcctaatatc gttagagcca tctatcagga aaataaaggc catggcggtg cggtcaatcg
     4621 tggcttggca gaggcttctg ggcgctattt taaagtagtt gacagtgatg actgggtgga
     4681 tcctcgtgcc tacttgaaaa ttcttgaaac cttgcaggaa cttgagagca aaggtcaaga
     4741 ggtggatgtc tttgtgacca attttgtcta tgaaaaggaa gggcagtctc gtaagaagag
     4801 tatgagttac gattcagtct tgcctgttcg gcagattttt ggctgggacc aggtcggaaa
     4861 tttctccaaa ggccagtata tcatgatgca ctcgctgatt tatcggacag atttgttgcg
     4921 tgctagccag ttctaactgc ctgaacatac tttttatgtc gataatctct ttgtctttac
     4981 gccccttcag caggtcaaga ccaggtacta tctgcctgtc gatttctatc gttatttgat
     5041 tgggcgtgag gaccagtctg tcaatgagca agtgatgatt aagtgcattg accagcaact
     5101 caaggtcaat cgactcttgg tagaccagct tgatttgtcc caagtgagtc atcctaaaat
     5161 gcgagaatat ctgctgaatc atattgaaat cacgacggtg atttccagta ccctgctcaa
     5221 ccgatctgaa acagcggagc atctggcaaa aaaacgccaa ttgtggacct atattcagca
     5281 ggaaaatcca aaagtctttc aggctattcg taagaccatg ttgagccgtt tgaccaaaca
     5341 ttctgtcttg ccagatcgca aactgtccaa tgtcgtctat caaatcacca aatctgttta
     5401 tggatttaat taatataagt gttttataag agggatttaa gaaaaatttt aactttttct
     5461 tagtcctttt taatttcagg agattatact agagtcatca aataaagaaa gactctaagg
     5521 agaatcctat gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca
     5581 gtgtcggtgt tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa
     5641 gttctgtacg tgccgatggg ctcaatccga ccccaggtca agtcttacct gaagagacat
     5701 cgggaacgaa agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga
     5761 aacctgaggg cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag
     5821 tgagcgagga aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc
     5881 aagaaaatcc agagctaaca gatgccttaa aagaaactgt agatacagct gatgtggatg
     5941 ggacacaagc aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa
     6001 atacaaaaga cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc
     6061 ctttcactgc cggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt
     6121 taactcgtct attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta
     6181 aaaatcctgc tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag
     6241 acttaaatgg caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta
     6301 atggtactca aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg
     6361 acttgactaa tctagttgct actaaaaatg tagacatcaa catcaatgga ttagtt
//
LOCUS       DBEROT010000072         6008 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.72, whole genome shotgun sequence.
ACCESSION   DBEROT010000072 DBEROT010000000
VERSION     DBEROT010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.72"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            171..371
                     /locus_tag="ACL8CG_002055"
     CDS             171..371
                     /locus_tag="ACL8CG_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344589.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            396..812
                     /locus_tag="ACL8CG_002056"
     CDS             396..812
                     /locus_tag="ACL8CG_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGS1344590.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGMEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1043..1750
                     /gene="ccdA2"
                     /locus_tag="ACL8CG_002057"
     CDS             1043..1750
                     /gene="ccdA2"
                     /locus_tag="ACL8CG_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS1344591.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1761..2318
                     /gene="sdbB"
                     /locus_tag="ACL8CG_002058"
     CDS             1761..2318
                     /gene="sdbB"
                     /locus_tag="ACL8CG_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGS1344592.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGQEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2692..4083
                     /locus_tag="ACL8CG_002059"
     CDS             2692..4083
                     /locus_tag="ACL8CG_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGS1344593.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4226..5143
                     /gene="adcAII"
                     /locus_tag="ACL8CG_002060"
     CDS             4226..5143
                     /gene="adcAII"
                     /locus_tag="ACL8CG_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGS1344594.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5151..>6008
                     /gene="phtD"
                     /locus_tag="ACL8CG_002061"
     CDS             5151..>6008
                     /gene="phtD"
                     /locus_tag="ACL8CG_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGS1344595.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLS"
BASE COUNT         1836 a         1084 c         1269 g         1819 t
ORIGIN      
        1 agtaaaatga aataagaaca ggacaaatcg atcaggacag taaaatcgaa ttctaacaat
       61 gttttagaag tctatatgta ctattctagt ttcaatatac cataactgct cctagtcaac
      121 ctgcaagtcc tgtcccagct ccaagctcag ctccgactca agatcctaga gtggtagcaa
      181 gcgcttcggc tagctcaacg agcacacaag ctcaagagca agttgacaag tctgaacttc
      241 gtgccttgag tcaagagtta gaccaacgct tgaaagcttt ggcaacagta tctgatccaa
      301 aaatcgatgc aaccaaggct gtcctcctag atgctcaaaa agctccggaa gatagtgcct
      361 tgacagagta aggtctgcat actgcagtag agtctgtgaa ggctgccttg gactctctca
      421 aagatgtgaa agcaaatgct agcgacagca agcctgcaca ggacaagaag gatgcaaaac
      481 aaggaatgga agatagtaag gattcagata agatgactga aacaaactca gttccggcag
      541 gcgtgattgt ggtcagtcta cttgccctcc taggcgtgat tgccttctgg ctgattcgcc
      601 gtaagaaaga gtcagaaatc cagcaattaa gcacggaatt gatcaaggtt ctaggacagc
      661 tagatgcaga aaaagcggat aaaaaagtcc ttgccaaagc ccaaaacctt ctccaagaaa
      721 cccttgattt cgtgaaagaa gaaaatggct cagcagagac agaaactaaa ctagtagagg
      781 agcttaaagc aatccttgac aaactcaagt aaaacatgat ttatgaaatg tcagacctaa
      841 aagacatttt cgttcacaaa agcagtgacg agtaatcctt gtcgttgctt tttggctatt
      901 ttgggggata agatccgcct tgactagcaa aagaaaagat tggtccaata gtgcccgata
      961 cgattttgcg tagcagaaag cttacaaata aaattgaata tagtaaaata ggattagaat
     1021 tattaagaaa gttggttctt tattggaaac gatagtattt ttaatctctg tttttctagc
     1081 aggtgtttta tccttttttt ctccttgtat ttttcctctt ctgccagtct atgctgggat
     1141 tttattggat gatcaagaaa gtgcaaaaag cttttctttg tttgggagaa aggttctctg
     1201 gtcaggcttg attcgaacac tttgctttat cgctggtatc tctctcattt tctttattct
     1261 aggctttggt gctggttact ttggtcatat tctctatgca aattggtttc gatatgtcat
     1321 gggagctatt attatcattt tgggtcttca ccagatggaa atttttcatt tgaagaaatt
     1381 agaagttcaa aaaagtttta cctttaaaaa atcagattct aatcgttatt ggtcagcttt
     1441 tttacttggt attaccttta gctttggttg gacaccttgt attggtccag ttttaagttc
     1501 tgttttagca cttgcggctt ctggaggcaa tggtgcttgg caaggagcga tttatactct
     1561 catttacact ctgggcatgg cccttccttt cttggtcttg gcactagctt caggtctagt
     1621 catgccatat tttagtaaaa tcaagcgtca tatgatgcta ctaaagaaaa ttggtggttt
     1681 cctcattgtt ttaatgggaa ttttgttact attaggacaa gtaaatgttc tagctggaat
     1741 ttttgaataa aggaggacaa atgaaaaaag taatgtttgc tggcttaagt ctcttgtcat
     1801 tagttgtatt gatggcctgt ggtcaggaag aaactaaaaa gactcaagca gcacaacagc
     1861 caaaacaaca aacgactgta caacaaattg ctgttggaaa agatgctcca gattttacat
     1921 tgcaatccat ggatggcaaa gaagttaagt tatctgattt taagggtaaa aaggtttact
     1981 tgaagttttg ggcttcatgg tgtggtccat gcaagaaaag tatgccagag ttgatggaac
     2041 tagcggcgaa accagatcgt gatttcgaaa ttcttactgt cattgcacca ggaattcaag
     2101 gtgaaaaaac tgttgagcaa ttcccacaat ggttccagga acaaggatat aaggatatcc
     2161 cagttcttta tgataccaaa gcaaccacct tccaagctta tcaaattcga agcattccta
     2221 cagaatattt aattgatagc caaggaaaga ttggaaagat tcaatttggt gctatcagta
     2281 atgcggatgc agaagcagca tttaaagaaa tgaactagaa tcgataaaat ctgattacaa
     2341 gatgtagtca gattttggta acttctaaaa ctaacttcca gtttcccaca acttagcttt
     2401 tagtatgaga aaaacgcgtg acatcagtgg aaatccgtct tagactaact ttcactggtt
     2461 ttctttttct tgatatataa gggttcaaaa gcgaaaagac tcagaaaaag tgcacgacaa
     2521 atagccctaa aacagagtcg tcttagagta acttccagtt ttgggagaga gatggaagtt
     2581 actttgagaa gttacggtag tcagattttt ttagaaaaac attttataaa tattcacata
     2641 tctcctatat ttatggtaaa atagaattat cagtttattt tggagtcaaa gatgaatata
     2701 tttagaacaa agaatgttag tttagataaa acagagatgc ataggcattt gaagttatgg
     2761 gatttgattt tgctgggtat cggagccatg gtagggacag gcgtctttac aatcacaggt
     2821 actgcagctg caacacttgc tggcccagcc ctagtgattt caatcgttat ttctgccttg
     2881 tgtgtgggat tatcagccct cttttttgca gaatttgcct cgcgagtacc cgctacagga
     2941 ggtgcctata gttacctcta tgctatctta ggagaattcc ctgcctggtt ggctggttgg
     3001 ttaaccatga tggagttcat gacagccata tcaggcgtag cttcgggttg ggcagcttat
     3061 tttaaaggct tgctctctca atacgggata gcccttcctc aggctttaaa tggtaccttt
     3121 aatcctcaag cagggacatt tgttgattta ttgcctattc ttgtcttggt cttggtgact
     3181 tcgcttgttt tactaaatgc caaggcagcc ttacgcttta attcgattct agttattttg
     3241 aaattttccg ctttagctct ctttgtttta gtaggaattt ggaatattaa gtttgataat
     3301 tggagcaatt ttgctcctta cggttttgga caaatctatg gagctagcac tggtattatg
     3361 gctggtgcgt ccttgatgtt cttcggtttt ttgggatttg aatccatctc tatggctgta
     3421 gatgaagtca agactcctca aaaaaatatt cctagaggga ttgtcttatc gctttctatc
     3481 gtaaccattc tctatgcctt ggtgaccctt gttttgactg gtgtggttca ctatagtcat
     3541 ttaaatgtcg atgatgccgt tgcctttgcc cttcgtagtg ttgggattag ttgggcagcc
     3601 aactatgtgt cattagtggc tatcttgacc ttgattacag tttgtatttc gatgacctat
     3661 gccctatcgc gtatgattta cagtttagca cgtgacggct tagtgcctgc tgcctttaag
     3721 gaactgacga agactagcaa gataccaaag aatgctacta tcttgacagg tctagcttca
     3781 gcagtagcag caggaatgtt cccactagcc agtattgcag cctttttaaa tatttgtacc
     3841 ttagcctact tgatcatgtt ggcttatggt ctgattcgct tacggaaaga aaaaggaatg
     3901 cccaaagctg gggaatttaa aacaccattg gtacctctgt taccaatttt atcgatcatc
     3961 atttgtttat ccttcatgtt acagtataat atgaatacct ggattgcttt cctagttgcg
     4021 ttgttagtag gaagtattat ttacttcact tatggctata agcattctac catagaagaa
     4081 taaagtgaaa gtctattgag ttgttgacac tcagcagatt tttatatgtg aaagaaattt
     4141 caaatttttt ctaaaaatat cttgacagat taaattttca ggagtagaat atttactagt
     4201 taattaaatg gttaaggagt tgttcatgaa gaaacaaaat ttatttttag tcctgttaag
     4261 tgtctttctt ttgtgcttgg gggcttgtgg tcaaaaggaa agtcagacag gaaaggggat
     4321 gaaaattgtg accagttttt atcctatcta cgctatggtt aaggaagtat ctggtgactt
     4381 gaatgatgtt cggatgattc agtcaagtag tggtattcac tcctttgaac cttcggcaaa
     4441 tgatatcgca gccatctatg atgcagatgt ctttgtttac cattctcata cactcgaatc
     4501 ttgggcagga agtctggatc caaatctaaa aaaatccaaa gtgaaggtct tagaggcttc
     4561 tgagggaatg accttggaac gtgtccctgg actagaggat gtggaagcag gggatggagt
     4621 tgatgaaaaa acgctctatg accctcacac atggctagat cctgaaaaag ctggagaaga
     4681 agcccaaatt atcgctgata aactttcaga ggtggatagt gagcataaag agacttatca
     4741 aaaaaatgcg caagccttta tcaaaaaagc tcaggaattg actaagaaat tccaaccaaa
     4801 atttgaaaaa gcgactcaga aaacatttgt aacacaacat acagcctttt cttatctagc
     4861 gaagagattt gggcttaatc aacttggtat tgcaggtatc tctcctgaac aagaaccaag
     4921 tccacgacaa ctaacagaaa ttcaggaatt tgttaagacc tataaggtta aaacgatttt
     4981 tacagaaagt aacgcttctt caaaagtagc tgaaactctt gtcaaatcaa caggtgtggg
     5041 tcttaaaact ctgaatcctt tagagtcaga cccacaaaat gacaagacct atttagaaaa
     5101 tcttgaagaa aatatgagta ttctagcaga agaattaaag tgaggaaaga atgaaaatca
     5161 ataaaaaata tctagcaggt tcagtggcag tccttgccct aagtgtttgt tcctatgaac
     5221 ttggtcgtca ccaagctggt caggttaaga aagagtctaa tcgagtttct tatatagatg
     5281 gtgatcaggc tggtcaaaag gcagaaaatt tgacaccaga tgaagtcagt aagagagagg
     5341 ggatcaacgc cgaacaaatt gttatcaaga ttacggatca aggttatgtg acctctcatg
     5401 gagaccatta tcattactat aatggcaagg ttccttatga tgccatcatc agtgaagaac
     5461 ttctcatgaa agatccgaat tatcagttga aggattcaga cattgtcaat gaaatcaagg
     5521 gtggctatgt gattaaggta gacggaaaat actatgttta ccttaaagat gcggcccatg
     5581 cggacaatat tcggacaaaa gaagagatta aacgtcagaa gcaggaacgc agtcataatc
     5641 ataactcaag agcagataat gctgttgctg cagccagagc ccaaggacgc tatacaacgg
     5701 atgatggtta tatcttcaat gcatctgata tcatcgaaga tacgggcgat gcctatatcg
     5761 ttcctcatgg caatcacttc cactatattc ctaagagtga tttatctgcc agtgaattag
     5821 ctgctgccca agcctattgg aatgggaagc agggatctcg tccttcttca agttctagtc
     5881 ataatgcaaa tccagctcaa ccaagattgt cagagaacca caatctgact gtcactccaa
     5941 cttatcatca aaatcaaggg gaaaacattt caagcctttt acgtgaattg tatgctaaac
     6001 ccttatca
//
LOCUS       DBEROT010000073         5146 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.73, whole genome shotgun sequence.
ACCESSION   DBEROT010000073 DBEROT010000000
VERSION     DBEROT010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.73"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            279..1824
                     /locus_tag="ACL8CG_002062"
     rRNA            279..1824
                     /locus_tag="ACL8CG_002062"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1876..1948
                     /locus_tag="ACL8CG_002063"
     tRNA            1876..1948
                     /locus_tag="ACL8CG_002063"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1909..1911,aa:Ala,seq:tgc)
     gene            2073..4974
                     /locus_tag="ACL8CG_002064"
     rRNA            2073..4974
                     /locus_tag="ACL8CG_002064"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5051..>5146
                     /gene="rrf"
                     /locus_tag="ACL8CG_002065"
     rRNA            5051..>5146
                     /gene="rrf"
                     /locus_tag="ACL8CG_002065"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1454 a         1041 c         1507 g         1144 t
ORIGIN      
        1 acacgggttc gaatcccgta cggactatgg tatgttgcgt caggagcact tgatgaaaaa
       61 aagtttaaaa aaacttaaaa atcttcaaaa aagtgttgac aattgaaagt ggctgtgata
      121 tactaatata gttgtcgctt gagagaagca agtgacaaag acctttgaaa actgaacaag
      181 acgaaccaat gtgcagggcg ctacaacata agttgtagta ctgaacaatg aaaaaacaat
      241 aaatctgtca gtgacagaaa tgagtgagaa ctcaaacttt taatgagagt ttgatcctgg
      301 ctcaggacga acgctggcgg cgtgcctaat acatgcaagt agaacgctga aggaggagct
      361 tgcttctctg gatgagttgc gaacgggtga gtaacgcgta ggtaacctgc ctggtagcgg
      421 gggataacta ttggaaacga tagctaatac cgcataagag tggatgttgc atgacatttg
      481 cttaaaaggt gcacttgcat cactaccaga tggacctgcg ttgtattagc tagttggtgg
      541 ggtaacggct caccaaggcg acgatacata gccgacctga gagggtgatc ggccacactg
      601 ggactgagac acggcccaga ctcctacggg aggcagcagt agggaatctt cggcaatgga
      661 cggaagtctg accgagcaac gccgcgtgag tgaagaaggt tttcggatcg taaagctctg
      721 ttgtaagaga agaatgagtg tgagagtgga aagttcacac tgtgacggta tcttaccaga
      781 aagggacggc taactacgtg ccagcagccg cggtaatacg taggtcccga gcgttgtccg
      841 gatttattgg gcgtaaagcg agcgcaggcg gttagataag tctgaagtta aaggctgtgg
      901 cttaaccata gtaggctttg gaaactgttt aacttgagtg caagagggga gagtggaatt
      961 ccatgtgtag cggtgaaatg cgtagatata tggaggaaca ccggtggcga aagcggctct
     1021 ctggcttgta actgacgctg aggctcgaaa gcgtggggag caaacaggat tagataccct
     1081 ggtagtccac gctgtaaacg atgagtgcta ggtgttagac cctttccggg gtttagtgcc
     1141 gtagctaacg cattaagcac tccgcctggg gagtacgacc gcaaggttga aactcaaagg
     1201 aattgacggg ggcccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga
     1261 accttaccag gtcttgacat ccctctgacc gctctagaga tagagctttc cttcgggaca
     1321 gaggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc
     1381 cgcaacgagc gcaaccccta ttgttagttg ccatcattta gttgggcact ctagcgagac
     1441 tgccggtaat aaaccggagg aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc
     1501 tgggctacac acgtgctaca atggctggta caacgagtcg caagccggtg acggcaagct
     1561 aatctcttaa agccagtctc agttcggatt gtaggctgca actcgcctac atgaagtcgg
     1621 aatcgctagt aatcgcggat cagcacgccg cggtgaatac gttcccgggc cttgtacaca
     1681 ccgcccgtca caccacgaga gtttgtaaca cccgaagtcg gtgaggtaac cgtaaggagc
     1741 cagccgccta aggtgggata gatgattggg gtgaagtcgt aacaaggtag ccgtatcgga
     1801 aggtgcggct ggatcacctc ctttctaagg ataaggaact gcgcattggt cttgtttagt
     1861 cttgagaggt cttgtggggc cttagctcag ctgggagagc gcctgctttg cacgcaggag
     1921 gtcagcggtt cgatcccgct aggctccatt ggtgagagat caccaagtaa tgcacattga
     1981 aaattgaata tctatatcaa atagtaacaa gaaaataaac cgaaaacgct gtagtattaa
     2041 taagagttta tgactgaaag gtcagaaaat aaggttaagt taataagggc gcacggtgga
     2101 tgccttggca ctaggagccg acgaaggacg tgacaaacga cgatatgcct tgggtagctg
     2161 taagtaagcg atgatccagg gatttccgaa tgggggaacc caacaggtag tacctgttac
     2221 ccacatctgt taaggatgtg aggaggaaga cgcagtgaac tgaaacatct aagtagctgc
     2281 aggaagagaa agcaaaagcg attgccttag tagcggcgag cgaaacggca ggagggcaaa
     2341 ccgaagagtt tactcttcgg ggttgtagga ctgcaatgtg gactcaaaga ttatagaaga
     2401 atgatttggg aagatcagcc aaagagagta atagcctcgt atttaaaata gtctttgtac
     2461 ttagcagtat cctgagtacg gcgggacacg tgaaatcccg tcggaatctg ggaggaccat
     2521 ctcccaaccc taaatactcc ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg
     2581 aaaagcaccc cgggagggga gtgaaataga acctgaaacc gtgtgcctac aacaagttcg
     2641 agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt acgttatgat
     2701 gcgaggttaa gttgaagaga cggagccgta gggaaaccga gtctgaatag ggcgccttag
     2761 tatcatgacg tagacccgaa accatgtgac ctacccatga gcaggttgaa ggtgcggtaa
     2821 gacgcactgg aggaccgaac cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc
     2881 ggagaaattc caaacgaact tggagatagc tggttctctc cgaaatagct ttagggctag
     2941 cgtcgacatt agagattctt ggaggtagag cactgtttgg gtgaggggtc catcccggat
     3001 taccaatctc agataaactc cgaatgccaa tgaattatgg tcggcagtca gactgcgagt
     3061 gctaagatcc gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc ccaaaataat
     3121 tgttaagtgg aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc
     3181 tattcattca aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac
     3241 cggggctaaa acaatttacc gaagctgtgg atacctttat aggtatggta ggagagcgtt
     3301 ctatgtgtga tgaaggtata ccgtgaggag tgctggaacg catagaagtg agaatgccgg
     3361 tatgagtagc gaaagacagg tgagaatcct gtccaccgta agactaaggt ttccagggga
     3421 aggctcgtcc gccctgggtt agtcgggacc taaggagaga ccgaaaggtg tatccgatgg
     3481 acaacaggtt gatattcctg tactagagta tgtagtgatg gagggacgca gtaggctaac
     3541 taaagcagac gattggaaga gtctgtctaa gcagtgaggt gtgaattgag tcaaatgctt
     3601 aattctataa cattgagctg tgatggggag cgaagtttag tagcgaagtt agtgacgtca
     3661 cactgccaag aaaagcttct agcgtttaaa catactctac ccgtaccgca aaccgacaca
     3721 ggtagtcgag gcgagtagcc tcaggtgagc gagagaactc tcgttaagga actcggcaaa
     3781 atgaccccgt aacttcggga gaaggggtgc tgactttaag tcagccgcag tgaataggcc
     3841 caagcaactg tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg
     3901 tgacgcctgc ccggtgctgg aaggttaaga ggagtgctta gcgtaagcga aggtatgaat
     3961 tgaagcccca gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt
     4021 cgggtaagtt ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac
     4081 tcggtgaaat tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc
     4141 atggagcttt actgcagttt gatattgagt gtctgtacca catgtacagg ataggtagga
     4201 gtctaagaga tcgggacgcc agtttcgaag gagacgctgt tgggatacta cccttgtgtt
     4261 atggccactc taacccagat aggtgatccc tatcggagac agtgtctgac gggcagtttg
     4321 actggggcgg tcgcctccta aaaggtaacg gaggcgccca aaggttccct cagaatggtt
     4381 ggaaatcatt cgcagagtgt aaaggtataa gggagcttga ctgcgagagc tacaactcga
     4441 gcagggacga aagtcgggct tagtgatccg gtggttccgt atggaagggc catcgctcaa
     4501 cggataaaag ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg
     4561 gaggtttggc acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt
     4621 tgggctgttc gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc
     4681 ggtccctatc cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac
     4741 cagagtggac ttaccgctgg tgtaccagtt gtcttgccaa aggcatcgct gggtagctat
     4801 gtagggaagg gataaacgct gaaagcatct aagtgtgaaa cccacctcaa gatgagattt
     4861 cccatgatta tatatcagta agagccctga gagatgatca ggtagatagg ttagaagtgg
     4921 aagtgtggcg acacatgtag cggactaata ctaatagctc gaggacttat ccaaagtaac
     4981 tgagaatatg aaagcgaacg gttttcttga tttgaataga tattcaattt tgagtaggta
     5041 ttactcagag ttaagtgacg atagcctagg agatacacct gtacccatgc cgaacacaga
     5101 agttaagccc tagaacgccg gaagtagttg ggggttgccc cctgtg
//
LOCUS       DBEROT010000074         4907 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.74, whole genome shotgun sequence.
ACCESSION   DBEROT010000074 DBEROT010000000
VERSION     DBEROT010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.74"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            83..445
                     /locus_tag="ACL8CG_002066"
     CDS             83..445
                     /locus_tag="ACL8CG_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGS1344596.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            844..1089
                     /locus_tag="ACL8CG_002067"
     CDS             844..1089
                     /locus_tag="ACL8CG_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344597.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFIKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            1490..2482
                     /locus_tag="ACL8CG_002068"
     CDS             1490..2482
                     /locus_tag="ACL8CG_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1344598.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2484..3302
                     /locus_tag="ACL8CG_002069"
     CDS             2484..3302
                     /locus_tag="ACL8CG_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344599.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3304..4089
                     /locus_tag="ACL8CG_002070"
     CDS             3304..4089
                     /locus_tag="ACL8CG_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1344600.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4128..4406
                     /locus_tag="ACL8CG_002071"
     CDS             4128..4406
                     /locus_tag="ACL8CG_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGS1344601.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4391..4588
                     /locus_tag="ACL8CG_002072"
     CDS             4391..4588
                     /locus_tag="ACL8CG_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1344602.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1414 a          804 c         1026 g         1663 t
ORIGIN      
        1 atctacaacc tcaaaacagt gttttgagca acctgaggct agtttcctag tttgctcttt
       61 ggttttcatt gagtataaca gattgttaga agttggttta aatttcctaa tcagtttgtt
      121 cacatttacc ttcgatatat tatatcccat agttaaggtt ggtcatacag atgattatag
      181 tcatggagcc gtaaaactta gtgtttcttt agttgacaaa gatgccatga aaaaaatatc
      241 tgtaactgta ataggatatt ttgaaataaa tatagatgaa aatatcaccg atattctata
      301 cgtaaatggt actgctattc tttatcatta tttacgttct attgtttcaa tagtttcggc
      361 aattgatagc agtgaagcaa tgttgctacc taccattaat gttttagagt tactagataa
      421 atctcaacct tttgaagaag aataatttat tagctcacta aattgagggt aaggaaaagt
      481 aaaatcagta agaaaaatgt cttgcattat acagcaacct tttgggaatg agtagatgga
      541 ttgaataaaa ttttattaag agtggatgat ttatctgtag attattattg gacagttagt
      601 cttgaagtag tctaagaatt aggttataat cagtagaatc cttgctaata atgaggaggt
      661 tagtttatgt atagtagact gaatctaaaa tagtacgaaa caattgctaa aacatttata
      721 gaaattaatt ttactttccc aatcgatttg ttctcatctt atttcaatcc gctatatatt
      781 atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga ttacaaacag
      841 aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga aagccttaag
      901 tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga tcagattgaa
      961 gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat tggattttat
     1021 aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg gtcgagttgg
     1081 tttaggtagt cgatgcgtga gttgataatt ctcagggtat ggacttcttt ttcatgaatg
     1141 aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc tggatagagg
     1201 gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat gagtaggttg
     1261 gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga gagaaatcct
     1321 aatttcacaa tccataggca aactcttgca tttcgttttt tattggacta taataggttg
     1381 gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga tttagaatat
     1441 ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata tggcaatgat
     1501 agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg gcttgaaggg
     1561 ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca aggatttgac
     1621 ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg ctgggaagtc
     1681 gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt gtcggattaa
     1741 cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg tagtctttgg
     1801 acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg tcttaaaaga
     1861 gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga atgaagtctt
     1921 ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac aacggatgcg
     1981 ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag atgagccgac
     2041 cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc agatcaatca
     2101 agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg agcaactttg
     2161 tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg tgagccaact
     2221 caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag gtcaaagtca
     2281 tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag gaaacagcct
     2341 caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc aaaccctgtc
     2401 tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata ttatccgtcg
     2461 cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa ccctttatca
     2521 atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat cggattggcg
     2581 atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat tcttcgcaag
     2641 agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc atgagttttg
     2701 tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag gtcaaggatg
     2761 gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat cttttcaccg
     2821 agcttggttc caagtggttg atttttatca gcgttggcct tccattttta agtgtcattg
     2881 tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta actgtccttt
     2941 atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt tgctttggat
     3001 tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact tccatagtgg
     3061 cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt tcagatattc
     3121 tttccttttt gcctttttca tccttgattt atactccagt tatgatcatt gttggaaaat
     3181 acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc ttagtgatgg
     3241 tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt caaggaggtt
     3301 agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat caaacaaatc
     3361 atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc tcaaggcttg
     3421 aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg ttggaccttt
     3481 caagagatag ctttcattta tggattttcc ttgattccca agggaatgga ccatctcttt
     3541 tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt tgacaagtat
     3601 ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca gattgatgcc
     3661 ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag cattgtttgg
     3721 actcttccga aattcctgct tttcctagtt tgtattcctt ttgcgacctt gatttatact
     3781 tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg cgccatgatt
     3841 tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta caattctctt
     3901 cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta tccagctagc
     3961 tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt gatttctctg
     4021 gttttctttg ttatttccct taaactttgg gataagggct tagattccta cgaaagtgcg
     4081 ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg tttgtaattg
     4141 aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg aaggatttgc
     4201 cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc acgacactgc
     4261 aagtttggac cgcctatcag gagagtgatt tgactagatt tgtaagctta tcctattcga
     4321 gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag gtagaaaaat
     4381 tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg gttatctgca
     4441 ggtcaaaaca gtggcagaag gttctaataa agattatgat cgaacaaatg acttttatcg
     4501 aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc aaaatccttg
     4561 tcagattttg attaaaaagc ttgaataata ttacttgaca tctattctca gagtgccata
     4621 ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt aaagcctagg
     4681 ttataggtag ataaacgact gaggagttga aaaaatagat aggtagaaga taaccgttaa
     4741 gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat caattatgcc
     4801 tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat ggtatgaatg
     4861 tgcttataat gtatcccggt taacgaaagt tttggactta tactctt
//
LOCUS       DBEROT010000075         4558 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.75, whole genome shotgun sequence.
ACCESSION   DBEROT010000075 DBEROT010000000
VERSION     DBEROT010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4558
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.75"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(60..1349)
                     /gene="hisS"
                     /locus_tag="ACL8CG_002073"
     CDS             complement(60..1349)
                     /gene="hisS"
                     /locus_tag="ACL8CG_002073"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGS1344603.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFATKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1427..2674)
                     /locus_tag="ACL8CG_002074"
     CDS             complement(1427..2674)
                     /locus_tag="ACL8CG_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGS1344604.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2867..3718)
                     /gene="rgg"
                     /locus_tag="ACL8CG_002075"
     CDS             complement(2867..3718)
                     /gene="rgg"
                     /locus_tag="ACL8CG_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGS1344605.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3842..4183
                     /locus_tag="ACL8CG_002076"
     CDS             3842..4183
                     /locus_tag="ACL8CG_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS1344606.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4247..>4558
                     /locus_tag="ACL8CG_002077"
     CDS             4247..>4558
                     /locus_tag="ACL8CG_002077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344607.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSSKHCFEVMDRTDEVS
                     PKHCFEVVDRTDEVSPKHCFEVVDRTDEVSSKHCFEVMDRTDEVSPKHCFEVVDRTDE
                     VS"
BASE COUNT         1455 a          945 c          903 g         1255 t
ORIGIN      
        1 aacttcaaaa cagtgttttg agcaatctgc ggctagcttc ctagtttgct ctttgatttt
       61 tattgagtat aaaatcctag tttttcaaag atttctgaaa agttttggct gattgtctca
      121 agtgacactt gcacttcttc tcgggtttgg ttgttcttga ccgtcacttg tccgctttcg
      181 acttcgctct ctcccagggt gatgagggtc ttagtcgcaa agacatcggc tgacttgaac
      241 tgagctttga gcttacggtt gaggtaatca cgctctgctt tgaaaccttg ttggcgaagg
      301 gcttggacta gttctagggc tttgacattt gctccatcac ccaagactgc gatatagaca
      361 tctaaggcat tttcgatagg gagggccacg ccttgttttt caaggatgag aagcagacgc
      421 tctacaccaa gcccaaaacc aaatccagca gtttcagggc ctccaaagta agcaaccaaa
      481 ccatcgtagc gaccacccgc acagactgtc aagtcattgc cctcaatctc tgtgataaac
      541 tcgaaaatgg tgtggttgta gtagtccaga ccacgcacca tattggtatc gatgatgtaa
      601 tctactccaa gattttccaa catctgacgc acagcatcaa aatgagcttg gctttcttca
      661 tcaagaaagt ccaagataga cggcgcattc tctactgcca ccttgtcttc tttttcctta
      721 gagtccaaga cacgaagagg attttcctcc aagcgacgtt ggctatcctt agacaaggtc
      781 tccttgagcg gtgtcaaata gtcaatcaag gcttggcggt aggctgcacg gctctcagga
      841 tttccaagag tgttgaggtg caatttgaca ccttgaatac cgatttcctt caaaaaatgg
      901 gctgccataa cgattgtttc cacatcggta gctggattgc tagagccaaa acactcaaca
      961 ccaatctggt ggaattggcg caagcgccct gcctgtggac gctcataacg gaacataggt
     1021 cccatatagt agaacttgct tggcttttgc acttctgggg cgaagagttt attttccaca
     1081 taggaacgga caacgggcgc agttccttct ggacggaggg taatatgacg gtcacccttg
     1141 tcataaaaat cgtacatttc cttggttacg atatccgttg tatctccgac agagcggctg
     1201 ataacctcgt aatgctcaaa aataggcgtg cgcacttctg catagttata gcgcttgaaa
     1261 atctcacggg caaagccctc aacgtactgc cacttagcag actcagcagg taaaatatcc
     1321 tgcgttcctt ttggtttttg taatttcata gggaatcctc tttaaactta atagtcttat
     1381 tttaccataa atagagggat taaaacagta agaaaaaaat taggatttag atatcatttt
     1441 tgagattaag aattgttaaa aaaatagcta gcaaggaaag accaacaaat agcatccaag
     1501 tcaactgcat gttccatacg gctactagtg aaaaacaagc tgttcccaca ggtatggata
     1561 aggtaaacaa tagacctaaa aaattactag tacgagctag aacctctgga gctagatttt
     1621 tcatgagcat ggcactaatc tttggttgaa ctttaccaga cacatacaga gtaaagaaga
     1681 gaaatagcaa accaagcacg acttgattga ataaattagc caaaccaact agactaagtc
     1741 ctacggtcgc ccacatcatc aatctaggca aggactgctt cccaaaataa gcattgcccg
     1801 taaggctact gatgatgatt gctactaaaa cacagaattg attgataaat agtgcctctg
     1861 tataagaaaa attcaagaga gaatggctca aaaagaagat attataaatt ccacccaaag
     1921 cgccacccaa ggaattaata agcaagacag caaagagcat aaaaccaaag tttttctgtc
     1981 cacttttaag aaaaacgaga cgtaaatttc ggtaaattgt taggaactgg tctttgatag
     2041 aaagcttctc attttttaag ttttcaccat cagcagatga cattgacagg ctcaatttgc
     2101 tttttcctaa aaagaggata gtggctgata ctaggaaaaa gcaggcattg attcccgcaa
     2161 cgagagaaaa attgttgacc gatagagcta agagccagac tccgaaagct tgaccaccaa
     2221 tagctgaaat ataggtgatg aactgtgaaa aagaataagc ctccatcaaa tcatcttcag
     2281 ctactttttc cttaataaga ggcatacgca ggccacctgc aaaatcactg atgatatcac
     2341 taatgacatt gatcaaacac aggctagaaa aggcaaagag actagcttgc tgaacaacta
     2401 gggctgctag aaaaaataga accgcctgaa acaaaccgct atagaccatc catttgacct
     2461 tgtccctcgt gtaatctgcc cgaatcccta caaaaactgt aaagagggtc ggaagaatca
     2521 tgacaatatt cgccatagca acagcaaaag atgcttgtga caaggtcgat gcatagacga
     2581 taaagaccag gttgaaaatc gaagcaccaa aagcattgaa gaagcgtgat aaaatcaaaa
     2641 ttctataagc tggatttcta aacaatagtt tcatagataa tctcccttct tgttcgaacc
     2701 tctatatgaa gtatgactat agtatagcac ttagaaattt gagagggaga actcttgaat
     2761 atatgcaaca aataaaatga gcaaaaagaa acgatagaac ttttgtaatg acctgagaga
     2821 gggcaatagt tctatcgctt caaatttttt cttggtttgc agatattcaa cattcagtcg
     2881 tatttctata gtattcggca gatttattac agccaagcat ctcaaaaata cggacagcat
     2941 cctccatctt tttctggcct tccttgactc taccttgctt gctatcaagg agaccttctg
     3001 cccacagata aacaattcgg aaataggtct cattttcctt gtagaaatgc tcttcgataa
     3061 cacgtttaaa ataataggca ttggtaaatt cttcacactc aatactagct aaaaagccat
     3121 tcaatagtat agtatgaaaa aggtttcgat tgccagacat ttccattaga aaatcagatt
     3181 tacgtaccat ttctcgtaca tatctagtaa aaagagaaac agataaaaat ggagaactga
     3241 ctgaaaataa attgagttca tagattcccc agatctcggt agaaaacaaa taatcatgaa
     3301 ggacttttcc ttcctctgct gttaactcta ccctttcatc catgctcttc atataagact
     3361 tgataataat ggcatttaga atatgtttct gtttgttgtg agaatgggca tgcttttgat
     3421 actccctgcg atataagtcc tcaagaggtg ctatattctt tggttccaag acatctgtaa
     3481 tttcttttct caactcagaa tctgtatcat actggaaacc tctcgccaga aagaggatct
     3541 cctccacact ggcagatata ttttccagag caaatagaaa cttttccacc gaaagctcac
     3601 tctgacctgt ttcaaaacgg gacaacatag acggcgaaaa ttgtcctccg gttgcttgtc
     3661 tcagtgagat atttcttgac tctcgtaatt gtctaaagac ttttccaatc tgctccatag
     3721 acttcccctt gattccgtat tttcttcatt ttatcatatt tttcagaaaa ttcatcaaaa
     3781 acttgccaaa ttgtcagaat tatgagaaaa tagaggatat ttatcacgtg gagggactgc
     3841 tatgagagac gatatcaaaa tcaatgaccg tgctttggcc ttgcaagacc aaattatcga
     3901 aaaactagag aaagtttttg atacagatgt ggaattggat gtttacaatc taggtctgat
     3961 ttatgaaatc aatctggatg aaacggggct ctgcaagatt gtcatgacct tcaccgatac
     4021 tgcctgtgat tgcgccgaaa gcctgcctat tgaaattgtg gcaggtctga aacaaatcga
     4081 gggtatcaaa gatatcaagg ttgaagttac ctggtcgcct gcttggaaaa tcacacgaat
     4141 cagtcgctat ggccgtattg cccttggact accacctcgt taagcaggcc aatcactttt
     4201 aaagatgaaa aaagcaagcc gaaaatggct tgctttttga tactcaatga aaatcaaagg
     4261 gcaaactaga aaactagccg caggttgctc aaaacactgt tttgaagtta tggatagaac
     4321 tgacgaagtc agctcaaaac actgttttga ggttatggat agaactgacg aagtcagccc
     4381 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agcccaaaac actgttttga
     4441 ggttgtagat agaactgacg aagtcagctc aaaacactgt tttgaagtta tggatagaac
     4501 tgacgaagtc agcccaaaac actgttttga ggttgtagat agaactgacg aagtcagc
//
LOCUS       DBEROT010000076         4180 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.76, whole genome shotgun sequence.
ACCESSION   DBEROT010000076 DBEROT010000000
VERSION     DBEROT010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.76"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(68..316)
                     /locus_tag="ACL8CG_002078"
     CDS             complement(68..316)
                     /locus_tag="ACL8CG_002078"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1344608.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(493..708)
                     /locus_tag="ACL8CG_002079"
     CDS             complement(493..708)
                     /locus_tag="ACL8CG_002079"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGS1344609.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGANYVKKLRQGYLK
                     KTQSRIPRHPPRRKQPYSYHRESCQAI"
     gene            1556..2428
                     /locus_tag="ACL8CG_002080"
     CDS             1556..2428
                     /locus_tag="ACL8CG_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGS1344610.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHVTSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2574..2918)
                     /locus_tag="ACL8CG_002081"
                     /pseudo
     CDS             complement(2574..2918)
                     /locus_tag="ACL8CG_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3061..3372
                     /locus_tag="ACL8CG_002082"
     CDS             3061..3372
                     /locus_tag="ACL8CG_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344611.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            3376..4092
                     /locus_tag="ACL8CG_002083"
     CDS             3376..4092
                     /locus_tag="ACL8CG_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1344612.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
BASE COUNT         1326 a          700 c          799 g         1355 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atcttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccctt
      481 ttttaattct ccctatatag cctgacaact ttcccgatgg tacgaatatg gttgctttcg
      541 tctaggtgga tgtcggggta ttcgggattg agtttttttg aggtagcctt ggcggagttt
      601 cttgacatag ttagcgccgt ctacttggaa gatgccgatg gtattatagt caatctgtgg
      661 ggtattcttg ataaataggt agtcgctgtt tcttatcttt ggctccatgg acttgctgac
      721 gacataagcg attgggtcgt agtcgtctgg gataatggaa actccataac taaatcgtcg
      781 tcctgcatcg agcggctacc tgcagagata aactacctaa cacgagagta agtagtctgt
      841 ctgtagtcgt ccagtctgat gatttttacg atacttcgtt tttctgatca tacagttgcc
      901 tctcggcata ggtcagaact ttaccttgtc tgggtggtgc ccgttggtcg tagatagatt
      961 ggatatcgct aggagaatcc ttttgaactg gaggaaagag ggcatcaatc aagctactga
     1021 atactttaac taagtcaaat atagtatttt tcttagtaga cctaaccctt ttttcataat
     1081 ttctaatggt gtttttactt atacctatct tagtacccaa ttcttattga gtccaaccat
     1141 tactagtcta tattgtttta tagttgattt agtttggaat agtacgctgt agctgctaaa
     1201 acatttctag gaattaattt gcctttccta atagagttgt tcatatctta tttcaatcta
     1261 ctatattttt cacctctaac aatcgcaatc tcttctttat ccatgaataa aaacgatttc
     1321 tatttttgta agtaaagcat cacacgaaat ccacgaaaat gaaaaccttt gttgtgtttt
     1381 cgtaaaaaat ttgttgacag agcacgaaac gcctactata attaaatcaa gtttaaggaa
     1441 ataacaaaaa aacaaatcgg agggaaagac gatgaacaca ttaaatgaga aagtaatcaa
     1501 tatctgtaaa gcagtagtta aagaaacttt aatccaagac atttaggaga aagaaatgaa
     1561 gaaatcaaga aaattagcca cattaggaat ctgttcagct ttgtttttag gcttggctgc
     1621 ttgtcaacaa caacatgtta cttctgaggg gacgaatcaa aggcaaagca gttcagcgaa
     1681 agttccatgg aaagcttcat acaccaacct aaacaaccag gtaagtacag aagaggtcaa
     1741 atctctctta tcagctcact tggatccaaa tagtgttgat gcatttttta atctcgttaa
     1801 tgactataat accattgtcg gctcaactgg cttatcagga gatttcactt cctttactca
     1861 caccgaatac gatgttgaga aaatcagtca tctctggaat caaaagaagg gcgatttcgt
     1921 tgggaccaac tgccgtatca atagttattg tcttttgaaa aattcagtca ccattccaaa
     1981 gcttgaaaag aatgaccaat tgcttttcct agataacgat gcgattgata aaggaaaggt
     2041 ctttgattca caagataagg aagagtttga tattctattt tcgagagttc caactgaggc
     2101 aactacagat gtcaaggttc acgctgaaaa gatggaaaca ttcttctcac aatttcaatt
     2161 caatgaaaaa gctcgaatgc tgtctgtagt cttgcacgac aatctggatg gcgagtatct
     2221 gtttgtaggc cacgttgggg tcttagtacc tgctgatgac ggtttcttat ttgtagagaa
     2281 attgactttc gaagagccct accaagcgat taaatttgct agtaaggaag attgctacaa
     2341 gtatttgggc accaagtatg cggattatac aggcgaggga ctggctaagc cttttatcat
     2401 ggataatgat aagtgggtta aactttaata gtgttatgat atgacagtaa tcttaggatt
     2461 tttatttcta tttttgatga cttggtgggt tatttcaatc gttaatagcc agaaaccacg
     2521 caaaaatgaa acatttattg gctatatcca aagatacgat attgatggga atggctatca
     2581 atcattaccg tgtcctcaga actgagagga gttcttgaaa tcgtaaaact actttgaaca
     2641 agagttactt caacccattg gctccgacgg attaagttgc tttcgtgaac accaaaatca
     2701 gccgcaattt cttcataagt gcggtattct cgcacatatt gaagagtggc cataagaagg
     2761 tcttctaggc ttaatttagg ttttcgtccc ccttttgtgt gtttaagttg ataagcagtt
     2821 tttaatacag ctaacatctc ttcaaaagtg gtgcgctgaa caccaacaag acatttaaat
     2881 cgtgcatcag ttagttgctt acttgcttca taattcatag aactactata ccatattttg
     2941 tttcgcagga agtctaatgc taaaatctta tcagtgagaa gatttcttaa agtttattct
     3001 ttgtagtttc atctgtatta gtatataatt taacttagag aaaataggag gactaatcga
     3061 atggaattaa aagattttac agaaaaagaa caggaaatga ttaagaaaag gcttacaatg
     3121 tctaatatta gtgacaaaga aactactgag aagattctgg cgctagtacc acaagacttg
     3181 attaagcgaa tcccgttttt tgtcagaaaa catgctacaa cacgtacgat taaacgcatt
     3241 tcaattgaac accctgaact ctacgctgta gctcaaacaa gtggtgagat tccagaaaaa
     3301 gaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct
//
LOCUS       DBEROT010000077         4041 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.77, whole genome shotgun sequence.
ACCESSION   DBEROT010000077 DBEROT010000000
VERSION     DBEROT010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.77"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(82..201)
                     /locus_tag="ACL8CG_002084"
     CDS             complement(82..201)
                     /locus_tag="ACL8CG_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGS1344613.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            166..315
                     /locus_tag="ACL8CG_002085"
     CDS             166..315
                     /locus_tag="ACL8CG_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGS1344614.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            782..2065
                     /locus_tag="ACL8CG_002086"
     CDS             782..2065
                     /locus_tag="ACL8CG_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1344615.1"
                     /translation="MVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKE
                     KIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLF
                     YILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLAEQQRIIEAIESALEKVDE
                     YAESYNRLEQLDKKFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFE
                     EGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIP
                     IYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIY
                     HENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELL
                     TKTIKEYLIPLPPLPEQSRIVDKIEQFFAHINALI"
     gene            2122..2919
                     /gene="psrA"
                     /locus_tag="ACL8CG_002087"
     CDS             2122..2919
                     /gene="psrA"
                     /locus_tag="ACL8CG_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGS1344616.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            2930..3538
                     /locus_tag="ACL8CG_002088"
     CDS             2930..3538
                     /locus_tag="ACL8CG_002088"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1344617.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(3486..>4041)
                     /locus_tag="ACL8CG_002089"
     CDS             complement(3486..>4041)
                     /locus_tag="ACL8CG_002089"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1344618.1"
                     /translation="NIPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIK
                     PLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGG
                     FIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLA
                     PFEEQELITQKVEKLFEKVNQLWK"
BASE COUNT         1442 a          602 c          677 g         1320 t
ORIGIN      
        1 aaagattgcc tgtgggtaaa cagtcacaca gcagtctaag ccatcaaata cctataaccc
       61 ttaaaatagc gatttcggtc gctatttatt tttcgaaaaa tcctcttgac tcttttgcga
      121 attagattta tcatcagacg tgtagaagaa aatcaaggag tcactatgga aaaattcaat
      181 ttcaaaaaca atatcgggca agaaaacaag ttacttcaaa tcgaaatcta caagtttact
      241 aacttttgca agcttcaaaa ttacacatct gtaaatattt tttcgaaaga tatatttgaa
      301 gccatagtaa attgagacta gaatagtaca ctacatctgc taaaaatttc tagaaactaa
      361 tttaactttc ctaatcgatt tgtttacatc ttatttcaat ctactatatt atctcaataa
      421 atgatgatgg cgactgtttt gtttgtgctt gtcgattttt gaatcctgat cgagcggaag
      481 aatatttctg ccgaggttgc caaggggaaa atcctgaaga tattgaattt tatgatgaac
      541 aattacaggc agaaaaggtg gaggttttga atattcgatt ggaagtaaaa aattgaatta
      601 tctacaatct catcaacaat aaacctattt caaccccatt atctataggc gtatttttac
      661 gcctttttat atacttgaag cacataagaa acattatggg aagtttgctg atggaagcac
      721 tcaagaaatt gatgttcctt atgatattcc tgatacttgg gagtgggtga ggttttctac
      781 attggttgaa attgtcagag gtggctctcc acgaccaatc aaagattatc ttacttctga
      841 agtagatgga ataaattgga taaaaatagg tgatactgaa aagggtgaaa agtatataaa
      901 taatgttaaa gaaaaaatca aaaaatcagg gcttaacaaa actagatttg taaaaaaagg
      961 tacatttttg ttaactaatt ctatgagttt tggtagacct tatattttga atgttgatgg
     1021 tgcaatacac gatggatggt tggctatttc gaactatgaa aactcattaa ataaagatta
     1081 cctattctat attctttcat caaatgtagt ttattctcaa tttctatctc taattagtgg
     1141 agctgttgtg aaaaacttga atagtgataa agttgcttct attcttatcc ctctccctcc
     1201 gctagctgaa caacaacgca taatagaagc aatcgaatca gctttagaaa aagtagatga
     1261 atatgctgaa agttataata gactagaaca gctagataaa aaatttccag ataaactaaa
     1321 aaaatctatt cttcaatatg ctatgcaagg aaaattagtt gaacaagacc caaatgatga
     1381 atcagtcgaa gttttacttg aaaaaatacg agcagaaaaa caaaaactct ttgaagaagg
     1441 caagattaaa aagaaagatt tggacatttc tattgtttcc caaggagatg ataactctta
     1501 ttatgaggaa gtaccttgtg aaataccaga aagttgggaa tgggtgaggt taaacgatat
     1561 aacctcctac attcaaagag ggaagtctcc aaaatattca aatattccta tataccctgt
     1621 gattgctcag aaatgtaatc aatggtctgg cttttctatt gacttagcaa gatttattga
     1681 tcccgaaaca gttcatagtt accagaaaga aagattacta agagatggtg atttaatgtg
     1741 gaattcaaca ggtctaggta cgttaggacg attagctatt taccatgaaa ataaaaatcc
     1801 ttatggctgg gctgttgcag atagccatgt tacagttata agagtcttat cgggagttat
     1861 taattgccat ttcatctata attttctttc ctctcctatt gttcagtcag ttattgaaga
     1921 aaaagcgtcg ggtagtacaa aacaaaaaga attattaacg aaaactataa aagaatattt
     1981 aatccccctc ccaccccttc ctgaacaatc cagaatcgtt gataaaatcg aacaattttt
     2041 cgcccatatt aacgcactaa tttagtataa tagttttacg tgcggtggaa tttctatcaa
     2101 acataagata ggagttttac gttgaaagat tttgaattac atttgaagaa agctggttta
     2161 gctgaaaata ctgtgcgttc gtacctttat ggtgttcgat ttttcttgga gaattacgaa
     2221 ctcaaaatgg aagatttatt tgaatacaaa ggatatttat tagacaattt taaacctaaa
     2281 actgtcaatt tgcgactaca aggagtaaat aaatatctgg cttttattgg tcatgatgat
     2341 ttgaaattaa aatttgtcaa agtacagcaa aaaccgtttt tagaagatgt cattagccat
     2401 gctgattacc tttttcttaa acgtagtttg aaaaaagatg gtattttaaa atggcatttt
     2461 gtcgtttggt ttttaggtgc aactggggct cgtgtaagtg aacttattaa actaaaagta
     2521 gagcatgtag aaatcggtta ttttgacatt tactcaaaag gtggtaaaat tcgtagactg
     2581 tacattccta aaaaattaag aaatagttgt cttagttggt tagaatcaga aaatcgccga
     2641 agtggttatt tatttttgaa taaatttaac gaaccaatta cagcaagagg agttgctcaa
     2701 cagttaaaaa attatgctga taaatacaaa atgaatccta aagtaattta ccctcattct
     2761 tttaggcatt tatttgctaa gaatttttta gcgaagtata atgatattgc cttgcttgca
     2821 gatttgatgg gacacgaaag tatagaaact actcgaattt atctaaggaa aacagctact
     2881 gaacaacaaa atattgtaga taaaattgtt aattggtaaa aaataacagg tggtcaaact
     2941 gactacctgc tatttttgtg attatggctc ttattatggg aataaagacg aaacaacctc
     3001 ttatcctata tatgaaatcc cagaagcatg gagatatatt aaatttgcta gcctagttaa
     3061 cttcagaata ggaaaaactc ctccacgcag tgaagctact ttttggggaa ctgaaatacc
     3121 ttgggtatct atatcagata tgcctatatc tggttatgta actaatacga gagaatctat
     3181 ttctaaatta gcattaaaat caaagaaaat agacatttca cctaaaggaa ctttattaat
     3241 gagttttaaa ttatctattg gaaaagttgc catattggat attcctgcca ctcataatga
     3301 agccattata tcgatattcc cctatgctaa taaagaaaat attatcagag attacttaat
     3361 gatatttttg ccacttatct ctactttagg tgattcaaaa gatgctatca aagggaaaac
     3421 attaaatagt accagtatct ccgaattatt aatccctatt tctaatcatg aagagatgaa
     3481 aagaatcatt tccaaagttg atttactttt tcaaaaagtt tctcaacttt ttgagtaata
     3541 agttcctgtt cctcaaaagg agctaacgga attaatagct cgcttagtgt agttttagga
     3601 atattatata aagcttgacc tgatagttta gttattgctt tcaattgttt ataaaataac
     3661 ggagaggaca agttaaataa tagaaatttt gaaataatct ctgaactttc gaatggtgtt
     3721 aattggaaaa taaatccacc agccacaaca ccatcatagt ctttatcgat tcttgcaaac
     3781 tttccaatat gttctaaaga ggttgataca ggtgttatta gctgattatg ttttaaataa
     3841 acttgctcag aggagatgaa ttgtgtatca atgtagtaat cgttatccaa cagagaaaat
     3901 tctaaaggct taatattacc accacgtata attctaacac ctttattatt aatgcttaaa
     3961 tcgcccttct tgtaagaaag acctgtattc attgaaaaaa tatcttttat ttttataaca
     4021 acccaattca taggtatatt c
//
LOCUS       DBEROT010000078         3921 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.78, whole genome shotgun sequence.
ACCESSION   DBEROT010000078 DBEROT010000000
VERSION     DBEROT010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.78"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..383)
                     /locus_tag="ACL8CG_002090"
     CDS             complement(<1..383)
                     /locus_tag="ACL8CG_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS1344619.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLS"
     gene            544..750
                     /locus_tag="ACL8CG_002091"
     CDS             544..750
                     /locus_tag="ACL8CG_002091"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344620.1"
                     /translation="MKLKKLLKDDTKVFEKSTFKFVEGYKIYLTESKESGIKQMDNVI
                     KYFEFIESKSIALYFQKRLNELID"
     gene            complement(1104..1637)
                     /locus_tag="ACL8CG_002092"
     CDS             complement(1104..1637)
                     /locus_tag="ACL8CG_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGS1344621.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1726..2502)
                     /gene="recX"
                     /locus_tag="ACL8CG_002093"
     CDS             complement(1726..2502)
                     /gene="recX"
                     /locus_tag="ACL8CG_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGS1344622.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKW
                     INDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2540..3895
                     /gene="rlmD"
                     /locus_tag="ACL8CG_002094"
     CDS             2540..3895
                     /gene="rlmD"
                     /locus_tag="ACL8CG_002094"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS1344623.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1264 a          655 c          703 g         1299 t
ORIGIN      
        1 gaaagctgat gggcaatatc ggtcatagaa atcttttcaa ttaacttttg cgcaattttt
       61 tggttgataa tacgagggat ttggtgattc ttcttgacga tagaagtttc agcgaccatc
      121 atttttgaac agtgatagca cttgaaacga cgctttctaa ggagaattct agaaggcata
      181 ccagtcgttt caagataagg aattttagaa ggtttttgaa agtcatattt cttcaattgg
      241 tttccgcact cagggcaaga tggggcgtcg tagtccagtt tggcgatgat ttccttgtgt
      301 gtatccttat tgatgatgtc taaaatctgg atattagggt ctttaatatc gagcagtttt
      361 gtgataaaat gtaattgttc catatgaatc tttctaatga gttgttttgt cgcttttcat
      421 tataggtcat atgggacttt ttttctacaa caaaataggc tccataatat ctataaggga
      481 tttacccact acaaatatta tagagccgaa aattcacatc taatatatgc agactacttt
      541 gaaatgaaat taaaaaaatt attaaaggat gacacaaaag tttttgaaaa atctacattc
      601 aaatttgtag aaggatataa aatatacctg acagaatcta aagaatctgg aattaaacaa
      661 atggacaatg tcataaaata ttttgagttt attgaatcta aaagtattgc tttatatttt
      721 caaaaacgat taaatgagct gatagattaa atagcatttt ctctgttgag atattgtttt
      781 taaaatattg tactaaatga ttgatgctat gtggaaatac aaaaaaatgt ttttgatacg
      841 aagttgacct gtatttttta tactaatcat tttcgtattt tttgtattaa acgatataag
      901 tttgttgtaa acttacaagg aataaagaca ttaaaaaata acagtatatc tatttgtttt
      961 atatatttta cgaattttgc ataaatctct ttctagtaat gtgttgtaac tctgctataa
     1021 tagatttatt cctttttgtg tttacacaat ttattttata ctaccaaaaa aggtcaggat
     1081 tttgttcctg acctttgaca actttaccga ttctttagtt ctacatagcg cttgtaccaa
     1141 atgtttacat aggcttctga gaaaggacca cgtccattgt taatccaatc aacaagaatt
     1201 ttgacatgtt cttttaaaat atagtccaag tcatcagaat aattcatttt gcgtttgtga
     1261 cgctcgtact cttcaacgtc caagagacgt ttttccccat ctgtaaaaat tttaacatcc
     1321 aaatcgtaat caatatactt cagtgcttct tcatccagat agtaggggct agccatattg
     1381 caatagtaag aagttccatt atcacgaatc atggcaatga tattaaacca atatttcttg
     1441 tgaaagtaaa caatagccgg ttctcgagtg acccaacgac gaccatcact ttcggtaaca
     1501 agtgtatgat cgttgacacc aataatggcg ttttctgttg tttttagtac catggtgtcc
     1561 cgccaagttc ggtggagact cccatcatgc ttataacttt gaattgtaat aaagtcgcct
     1621 tcttttggaa gcttcataac taaccaactt tctacaattt ataagtttat catttactat
     1681 tgtaccataa aattacccaa aatctgtgaa tttcacttgg aaatattaaa gatattctct
     1741 aagagcgctt gctatatccg aaaaatcgta gccctttcgt gctaaaactt gagttaaacg
     1801 ctgcttcagt tcgtatcctt catactttcg ggcatactta gtatattgct tatcaagttc
     1861 cttgaagatg agttcctgag tcgtttcttc atcaacttga ctatccaatt cgtcaaaggc
     1921 aattttagca tcaaaataag agaagccctt gttagtcaag ttctggataa tcttatcttg
     1981 cagggcacga gctggaagtt ttccctcata ttttttcaat agtttattgg ctacacgttg
     2041 agcaacttcc gaaaaatcaa aatcattcaa gatttcttct atagtagatt ttgaaattcc
     2101 tttttgtgct aatttctgag tcagtacata aggtcccttg tctcctgaaa gttgattggc
     2161 attgatgata gcataagcgt actggctatc attaatccac ttctcttctt taagattagc
     2221 aatgacttga gaaacgatgt tttcattaat atcatatttt ttcagatatt ctctgacctc
     2281 tttttcagta cgtgctttaa aggataagtg gtagagggcc agattcttac cataagaaaa
     2341 ttgagcaaag tcttgaatct ctttcaattc ctcttcgctt atcaccttat ctctcgataa
     2401 cataaaacga acaattgtgt cttcggtgat atagcatttg tcgccattat caagctccat
     2461 cagatagagt ctttttttct tttcaagttt tgtgattttc atagctctat tataactcaa
     2521 aatgtgataa gataggggta tgaatctgaa agtgaaacaa aaaataccat taaaaatcaa
     2581 gcgcatggga attaacggtg agggaatcgg cttttaccaa aaaacattag tctttgtacc
     2641 aggagctctc aaaggcgaag atatctattg tcagattact tctattagac gcaactttgt
     2701 tgaagcaaaa ttactgaagg tcaacaagaa gtctaaattt cgaattgtgc catcttgtac
     2761 tatttataat gaatgcggag gctgccaaat catgcacctg cattatgata agcagctgga
     2821 gttcaagacg gacttacttc atcaagcgct gaaaaaattt gctcctgcag gatatgaaaa
     2881 ttatgaaatt cgtccaacta ttggaatgca ggaaccaaaa tattacagag ctaagttaca
     2941 atttcagact cgaaaattta aaaatcaggt caaggcgggc ttatatgcac aaaactctca
     3001 ctatttagta gagttgaaag actgcctggt acaagataag gaaacccaag tgattgctaa
     3061 tcgcttagca gaattactta cttatcacca gattccaatc acggatgaga gaaaagttct
     3121 aggtgtccgt actattatgg tccgacgcgc gagaaagacc ggacaggttc agattattat
     3181 tgttacaaac cgccagctta atttaactca attggtaaaa gagttggtta aagatttccc
     3241 agaagttgtg acagtagctg ttaatacaaa tacagctaaa accagtgaga tatatggtga
     3301 aaagacagag attatctggg ggcaagagag tattcaagaa ggtgtactca attatgaatt
     3361 ttcactatcc cctcgagctt tttatcaact aaatcctgag caaacagaag tcctctatag
     3421 cgaagcagta aaagcgctgg atgttgataa agaagaccat ttgattgacg cttattgtgg
     3481 agttggaacg attggatttg cctttgcaaa gaaagtaaaa acactcagag gtatggatat
     3541 tattccagaa gctattgaag atgccaagcg aaatgctaaa agaatgggat ttgacaatac
     3601 tcattatgaa gctggaacgg cagaagagat tattcctcgt tggtacaagg aaggctaccg
     3661 agcagatgct ttgattgttg acccaccacg tacaggtctg gatgataagt tattagatac
     3721 tattcttact tatgtaccag aaaaaatggt ttatatttct tgtaatgttt cgaccttggc
     3781 tcgtgatttg gtacgcttag tagaagtcta tgatcttcat tatatccagt cggtcgatat
     3841 gttcccacat acagctcgaa ctgaagctgt tgtaaaatta ataaaaaaag tttaaaaaag
     3901 tagttgacaa agtttgaaaa g
//
LOCUS       DBEROT010000079         3142 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.79, whole genome shotgun sequence.
ACCESSION   DBEROT010000079 DBEROT010000000
VERSION     DBEROT010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.79"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            189..392
                     /locus_tag="ACL8CG_002095"
     CDS             189..392
                     /locus_tag="ACL8CG_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344624.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(479..1066)
                     /locus_tag="ACL8CG_002096"
     CDS             complement(479..1066)
                     /locus_tag="ACL8CG_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344625.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            1220..1417
                     /locus_tag="ACL8CG_002097"
     CDS             1220..1417
                     /locus_tag="ACL8CG_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344626.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNNKK"
     gene            2184..3142
                     /gene="ltrA"
                     /locus_tag="ACL8CG_002098"
                     /pseudo
     CDS             2184..3142
                     /gene="ltrA"
                     /locus_tag="ACL8CG_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         1085 a          574 c          635 g          848 t
ORIGIN      
        1 tagaaaacaa ttatgttgat agagcttggg caagagccca atttcagcaa aaaatgaagt
       61 aaatcttctc ataataaaac gcatcatatc aagcacgaaa attccacgag gtcaactaca
      121 gtcagaaagc tgaacaacaa gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg
      181 caagcaacgt gccgaaatgg tcaaatcctg attatgtcaa cgaattagac ccaaaaatcg
      241 ttgatatgct agtagaattt cacaagtcac aaggcacttt ggaaactccc gaggcgcaag
      301 cagaaatcgc ccaaaaacgt gaagaaatcg agcaaaggag agctgagctt gagggtaaaa
      361 aacaagagct tttgaaccgc ttgaacaaat agagtttcgc aagtattatg cttacaaatt
      421 acttgagcaa ttaactaaaa tataaaccct gcctttatat ctaggcaggg tttatatttt
      481 agaaattcac ataggttgtt acggttttta catacccagt atagtttgag tttctatagt
      541 attcagtgat aaacttccat tttctttgag caacatggat ataagtactt gttatgtagt
      601 atggatatgg gctttgtgaa tccaagtaag actgataagc ttgtatacca aaatatgctc
      661 caccaattat tgcaccccat ggccccccca ataaagcacc tatcctacca atcatataac
      721 tgattccagc accagtcatg aagttagcga atgtgttagc ttgtttattc ccatgtattg
      781 tgttgacgta attccaaaca ttaggatcgt atgatctaaa agatatattt aggtcgattt
      841 cattcttttg ataagccata taaaatgccc cattgatata gacgccgtca gcacgtcgtt
      901 caatagtgtc tacacttcca tctggattga caacctcaag aacttcatcg cttaaaatat
      961 ttacttgcgt atctccgaac cgcactgatg agccattctc aaactgagcc tcaccagata
     1021 caactttaga gtttgccgat aagctatcat cagcaaaaac aaacaagcga cggggaaatg
     1081 ctagacatac agaaaacaga cataactagc aaacacatgc atttaaacat cttagacata
     1141 acggaaactc ctttgtattt ttgatttttt tcaactttta ttatacaata aaaccaaata
     1201 aaaagaaagc ggtaacaata tgcttaatgc gaaaattttt tatatatttt tatgtttgat
     1261 cgttatcgaa actacaggct tgttgttgtt gaaaagaggt ctcgaaatgg gttatttaga
     1321 cacagaagct attatcctcg cagttttttc atttgctttt tacaacctat gttcattcgc
     1381 ttgggtctgc tctacaataa aaaacaataa aaaataaata gacgtatttt caaaaaaaaa
     1441 aaaaaaaaaa aatgcatatt tatcttagca aaacgacgat ttaaatcgtc gtttttttgt
     1501 agtacgacgg gcatgtcgta tatctgaggt gtaagtcctc ggtgggcacc tgctaccggt
     1561 gaacccaata gcgattccca agcctgacta tcgtgaggta gcagggagag gaagggatag
     1621 cgaaatcgtg gctctacgaa caggaacgtg atagtaaggc gtatatagcg gataaggagg
     1681 cttcaaactc taaagtccaa aaaggtagtc gtaacctata tgcgtaaatc acgagagtaa
     1741 ttgaattcgg actaaggttt gtgtgaaaag ataaatcttt ctagagtcta aagactctgc
     1801 gtcagatttc ctattttcac tgtaaccttt taacgtcctc atatcttgta taaacgagga
     1861 aagatgtacg acttatcccg tgaggtctca tgagtgctga aagcgtagta acaacgaatc
     1921 atgagaagtc agccgaaccc atagtagtga ggaaacttcc gtaatggaag tggagcgaag
     1981 gggtgaatac tcaaacagtc tggggagaga ctgtttgagg tctgtcgcta gaaagagaaa
     2041 acgacagatt gaagtaatcc tacttcactt gtgtctgtaa aacgagaggt ctgatagaac
     2101 tggagtctgt cacgtattga ctagatgaag gctcaccaat ataagatgtc cctcaggcac
     2161 caaaacaaga aaggaatacg cacatgtcaa aattgctaga taagatatta tcacgcgaaa
     2221 atatgctgga agcctacaat caagtaaaat ccaataaagg ctcagctggg attgatggaa
     2281 tgactatcga agagatggat aattatctca gacaaaactg gcgcttgact aaggaactga
     2341 taaaacagag aaaatataag cctcaaccag ttcttagagt tgagatacct aaaccagacg
     2401 gaggtatccg tcaactagga attccaacag ttatggatag aatgattcaa caggccattg
     2461 tctaagtcat gagccccatt tgtgaacccc atttctcaga tacgagttat ggtttcagac
     2521 caaataggtc atgtgaaaaa gccatcatga agctcttaga atacttaaat gacggctatg
     2581 agtggatagt ggatatagac ctagagaaat ttttcgatac agttcctcaa gatagattga
     2641 tgtccttagt acataacatt atcgaagacg gagatacgga atccttgatt cgtaagtatc
     2701 ttcattcagg tgttatcatt aatggtcaac gttataaaac actagttggt acaccacagg
     2761 gaggaaattt atctcctctc ttatccaata tcatgcttaa tgaattggac aaggaattag
     2821 aaaagagggg acttcgattt gtgcgctacg cagatgattg tgtgattacg gtcgtaagcg
     2881 aggcagccgc taagcgtatg atgtattcag tcagtcgttt tattgaaaaa cggctaggtt
     2941 tgaaagtaaa catgaccaag actaagatta ccagaccaag agagttgaaa tatctaggtt
     3001 ttgggttctg gaaatcatca gatggttgga aaagtcgtcc acatcaagat agtgttcgga
     3061 gatttaagct taaattgaag aaactaacac agaggaaatg gagtatagac ctaacaagac
     3121 gtattgagca actgaatttg tc
//
LOCUS       DBEROT010000080         3030 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.80, whole genome shotgun sequence.
ACCESSION   DBEROT010000080 DBEROT010000000
VERSION     DBEROT010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.80"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..1348
                     /gene="dcm"
                     /locus_tag="ACL8CG_002099"
                     /pseudo
     CDS             1..1348
                     /gene="dcm"
                     /locus_tag="ACL8CG_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            1332..1781
                     /locus_tag="ACL8CG_002100"
                     /pseudo
     CDS             1332..1781
                     /locus_tag="ACL8CG_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1774..2154
                     /locus_tag="ACL8CG_002101"
     CDS             1774..2154
                     /locus_tag="ACL8CG_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS1344627.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIGLPFVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            2167..2400
                     /locus_tag="ACL8CG_002102"
     CDS             2167..2400
                     /locus_tag="ACL8CG_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGS1344628.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQILDLDYEDLFRR"
     gene            2403..2990
                     /locus_tag="ACL8CG_002103"
     CDS             2403..2990
                     /locus_tag="ACL8CG_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1344629.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
BASE COUNT          991 a          452 c          643 g          944 t
ORIGIN      
        1 agatttattt gctgggatag gaggctttag gatgggaatg gaagctcaag ggcatgagtg
       61 cttgggattt tgtgagattg ataaatttgc taggaaatct tataagtcca tttttcaaac
      121 ggaaggagaa atagaatttc atgacatacg agatgtttca gatgacgaat ttaaaaaact
      181 tagagggaaa gtcgatgtca tctgtggggg attcccttgt caagcatttt caatcgcagg
      241 aagacgattg ggatttgaag atactagagg aactttgttc tttgaaattg ctcgggcggc
      301 caaacaaatc caaccacgtt ttctttttct tgaaaatgtt aaaggcctac tcaatcacga
      361 taagggacgg acgttcacca caatacttac cacacttgat gagttggggt ttgatgttga
      421 gtggcaggtg cttaacagta aggattttgg cgttcccaaa aacagagaga gggtgtttat
      481 tatcggacat tctagaaaga aaggtaccag actcttattt cctttcagac gagaaggtca
      541 agcaactaac tctgagactt tgaaagcact aggaaatttg aatccatcaa gaagtggaat
      601 gagcggtaaa gtctattatt cagaaggtct tgcgccaacc ttagttcgtg gtaaaggaga
      661 aggatttaaa gttgcgattc cttgtatgac accagataga ttagacaaga gacaaaatgg
      721 gagacgcttt aaggaaaatc aagagccgat gtttacttta aatactcagg atcgttatgg
      781 cattgtcgtt gttggagatt taccgactag ctttaaggag acaggtcgtg tctatggaag
      841 tgagggctta tctccaacac tgactacgat gcaaggagga gataaaatcc ccaaaatact
      901 aattccagaa ccaatccaat ttctaaaagt acgggaagca acgaaaaaag gatatgctca
      961 agcagagatt ggggattcaa tcaatttaga aagaccaagt tctcagtatc gtcgtggtag
     1021 agttggaaaa ggtatagcta atacgttaac aactagtggt caaatgggag tagtagtggc
     1081 tagctatgaa ggagaagata aacaagttta ccaagtagct ggtgttttaa tagatggaca
     1141 attttaccgt ttgagaatac gacgaatcac tcctaaagag tgttttcgat tgcatggctt
     1201 tcctgattag gcttttgaag ctgctagaaa agtctctatt aatagtcagc tctataaaca
     1261 agttggtaat agtgtaaccg ttcctgtgat tgccgcaatc gcaaagaaat taaaagaaat
     1321 agaggaaaaa gataaaagca ttaaataaag aatcaatact agattgtgat gaattagaaa
     1381 cagaattaca tgatgcagaa atcaaacagc tggatgaaca aatatttttg atgcccaatt
     1441 atccatgtga gtttgaggta acatttttag atgattacca taaaaaacat aattacccac
     1501 tattttatga atcctatctt caaaacgtta tggaattcct tgaaagtcag gatataaaga
     1561 acggagttaa tgcctttgta gatgataatc agaatcttgt ttttgtttta tattgacaag
     1621 actatcgagc cgagggaaaa gaggggatac ttacaaccca agtaactgta aaagcttatg
     1681 atgaagacaa gaaatcgatt aacttctcaa agttgttaga ttccttaatc gtctcagaat
     1741 atcaaatgga agcaaatttg ttggaggtct cccatgattg atctctatct aagtaaaaat
     1801 agccaaagaa atcaacttct tttagacttc ttccaaaact atggcattga ggtatcttgt
     1861 cattcagttt ctgaaatgac aaaggacaaa ttaattgaga tgatgagcta ttcttcagat
     1921 tgttttgagt ttttatctcc caatttatta cgatttaaga accgtgacaa tctaagatta
     1981 acggatttcg ttgagataat tttaaaaaat cctgaactaa ccatcggact tccttttgtg
     2041 gtttcaaata agcgggttta tccaagtctg aatttggaag aggctagagc tctattgcca
     2101 agagatacga aacaattgat ttacatggca caaacacatt atttatctaa ctaaaggaga
     2161 agtaatatgg ctgaacgatt ttgggagaac ttgtccatta ttttggctga aagaaatatc
     2221 agctggattg agttaaccag aaaaatgttt gcgggagagt ttcactatcc aagtgaattg
     2281 aatcgtttat atcaaaagat tcgccactac aagatggaac aacgaatgcc tcaaagtcca
     2341 tgggtagaaa ggattgtgca gatattagat ttagattatg aagatttatt tcggaggtaa
     2401 ctatgaaaag aataattcca gtttatatat tccaacaagt aaatgtccta ttggtatctc
     2461 tatacttatt gaaatttctt tgtatcggtg agttaactat actacaggtt ctctatggtg
     2521 cgtctctttt ttctttttta tggatgtatg gtcaacgaaa acaagtggtc aaggtcaata
     2581 tgaaaactag gatgaaatgc cttggtattg gactagctag tctactgatt ataagtctat
     2641 gttttagcct gattcatgct caaggaagca cgaatcaaac aaatttaatt ggccttcaac
     2701 atcaagttcc ttggttttca tttttattgt tcttaatcaa tgcgagtatg gttgaagaat
     2761 ttctgtatcg tgaaatttta tggaacttgg ttagaaaatt agatattcga gttgctttga
     2821 caagtgtttt atttgcctta gtacatcatc caggaaccat tctagcttgg tgtctgtacg
     2881 tttcacttgg aatgttttta ggtatggtgc gctataaatc tgacttatgg ggaagtatgg
     2941 ggttacattt ggtgtggaac tttttagttt atagtttgct gcttttttaa aataggtgac
     3001 ctgatttatc tcataaatct gtagttttta
//
LOCUS       DBEROT010000081         3019 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.81, whole genome shotgun sequence.
ACCESSION   DBEROT010000081 DBEROT010000000
VERSION     DBEROT010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.81"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            327..1673
                     /gene="gdhA"
                     /locus_tag="ACL8CG_002104"
     CDS             327..1673
                     /gene="gdhA"
                     /locus_tag="ACL8CG_002104"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGS1344630.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2179..2349)
                     /locus_tag="ACL8CG_002105"
     CDS             complement(2179..2349)
                     /locus_tag="ACL8CG_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344631.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2362..2934)
                     /locus_tag="ACL8CG_002106"
                     /pseudo
     CDS             complement(2362..2934)
                     /locus_tag="ACL8CG_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          959 a          563 c          502 g          995 t
ORIGIN      
        1 tataatgctt tttgatttta gtctggtata aatattgctt tcctccaaaa tggtcatagt
       61 tttactggca aatctaacat atcacggata aattaacaag tgatttctga attgctaaac
      121 attttctttt cttatagcat actttaagat tttgtctttg agaaagatat ttccaagaaa
      181 aacgttcgtt tttttatcta ttttcaaaaa aaccaaaaaa ctgaattgaa agaattttta
      241 gaaaatttct gttttttctt tacagtgaaa aaaaattctg ctataatgtc ttatgtaata
      301 aaatatgaca ataaaaggag aacgatatga catctgctaa agaatatatc caaagcgtgt
      361 ttgaaactgt gaaagctcgt aacgggcacg aggctgaatt cctccaagct gttgaagaat
      421 ttttcaacac tttagaacct gtatttgaaa aacaccctga gtatatcgaa gaaaatatct
      481 tggcacgtat tactgagcct gagcgcgtgg tttctttccg tgttccttgg gttgaccgtg
      541 atggaaaaat tcaagtaaac cgtggttacc gtgttcaatt caactcagct gttggaccat
      601 acaaaggtgg acttcgtttc cacccaactg taaaccaagg gatcttgaaa ttcctcggat
      661 ttgaacaaat ctttaaaaat gtcttgactg gacttcctat cggtggaggt aaaggtggat
      721 cagacttcga tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc caaagcttca
      781 tgactgaatt gcaaaaacac atcggaccat cacttgacgt acctgctggt gatatcggtg
      841 ttggtggacg tgaaattggt tacctttacg gtcaatacaa acgtcttaac caatttgatg
      901 ctggtgtctt gactggtaaa cctcttggat ttggtggtag cttgattcgt ccagaagcaa
      961 ctggttacgg tttggtttac tatactgaag aaatgctcaa agctaacggt aacagctttg
     1021 ctggtaagaa agtcgttatt tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag
     1081 caactgaact cggtgcaact gttatttctg tttctgactc aaatggttat gtcatcgatg
     1141 aaaatggtat cgacttcgat cttttggttg atgttaaaga aaaacgtcgt gctcgtttga
     1201 ctgagtatgc agctgaaaaa gcaactgcaa cctaccacga aggtactgta tggacttacg
     1261 ctggaaacta tgacattgct cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag
     1321 ctaaacgttt ggttgctcaa ggcgttatct gtgtatctga aggtgccaac atgccgagcg
     1381 accttgatgc catcaaagtt tacaaagaaa atggtatctt ctacggacct gcaaaagctg
     1441 ccaacgctgg tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct
     1501 catggactcg tgaagaagtt gatggccgtc tcaaagacat catgacaaac atcttcaaca
     1561 cagctaaaac gacttcagaa acatacggtc ttgataaaga ctaccttgca ggagctaaca
     1621 ttgctgcctt tgaaaatgta gcaaatgcca tgattgcaca aggtattgtt taagatttat
     1681 ttactcaatc ctcaatcact acgattgggg atttttagct tgaattaaaa aattggaaaa
     1741 tctaattaaa taaaatgaaa tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc
     1801 aatttctaac atatttctag aaattaattt gacttttcta atcgatttgt tcatatctta
     1861 tttcaattta ctatacttac ttgacccttt ttatactcaa tgaaaatcaa agagcaaact
     1921 aggaagcgag ccgcaggctg tacttgagta cggtaaagca aagctgacgt ggtttgaaga
     1981 gattttcaaa gagtattaaa caaaaagaaa aaccgctact cctaagaata gcgatttaat
     2041 catgttttta agctactact gtagttgctc tattatttaa gtgttatgaa taacttcaat
     2101 atctttaaag ctttttgtta gatttataat ttcaactata gccatctcta ctccttagtt
     2161 tacagcaaaa aattatgctt aattcttatt gtttttgtaa acaatcagcg aacccaatac
     2221 tattccattc aacaagccta aagaaatacc atattcaact ggaaaatcta aaaaaattgc
     2281 aaacactatt ccaatcatca cccctagtga ggctgttgtt aaaattacat attcattttc
     2341 tttcttcatt ttctttacac ctcatttcct ttttgtatat aagctgtagt actctccacc
     2401 aagatccatt aagtacttat gatttcctga ctcaacaatc ttaccacctt tcattacaaa
     2461 aataacatcc gcatccttaa tcgttgacaa tctatgagct acaattattt gagtacagcc
     2521 ctgactttgt atatactttg ttattctttc ctcattaata gtgtctaatg cactagttgc
     2581 ttcatctaaa attacaatac taggattatt tattaatgca cgtgccagtg ctatccgttg
     2641 cctttgccca cctgaaatat ttgaccccat ctctgagatg atagtattaa atttcatcgg
     2701 catagccatg atttcatcat agatttgaac tgctttacaa acttcctcta tcttttgtga
     2761 agtaacttcg tgctttaaag ttatattatc aagaatactt cggttcaata aaaatgaatc
     2821 ctgtggaact actcctaaat tttgacttaa tattttttta tctatttgat taatatttac
     2881 accatcaaat aaaacttttc ctgtatcaat cttatataat cttgatggta tttttgataa
     2941 tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca atcaaattca
     3001 ttcgtaatcc gaagcgttt
//
LOCUS       DBEROT010000082         2922 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.82, whole genome shotgun sequence.
ACCESSION   DBEROT010000082 DBEROT010000000
VERSION     DBEROT010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.82"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..550
                     /locus_tag="ACL8CG_002107"
                     /pseudo
     CDS             1..550
                     /locus_tag="ACL8CG_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            625..1020
                     /locus_tag="ACL8CG_002108"
                     /pseudo
     CDS             625..1020
                     /locus_tag="ACL8CG_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621054.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1232..1624)
                     /gene="rpsI"
                     /locus_tag="ACL8CG_002109"
     CDS             complement(1232..1624)
                     /gene="rpsI"
                     /locus_tag="ACL8CG_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGS1344632.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(1643..2089)
                     /gene="rplM"
                     /locus_tag="ACL8CG_002110"
     CDS             complement(1643..2089)
                     /gene="rplM"
                     /locus_tag="ACL8CG_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGS1344633.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            2446..2763
                     /locus_tag="ACL8CG_002111"
     CDS             2446..2763
                     /locus_tag="ACL8CG_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGS1344634.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
BASE COUNT          913 a          570 c          538 g          901 t
ORIGIN      
        1 tcttctcata aaggagacgt tggtaagaaa gcagagaatc tcattcaagg ccaatttgaa
       61 ggctctaaaa caatggaaaa gtgctacaca gatgtgacag aatttgccat tccagccagt
      121 actcaaaagc tttacttatc accagtttta gatggcttta acagtgaaat tatcgcctat
      181 aatctttcaa cttcacccaa cttagaacaa gtacaaacaa tgttggaaca ggcattcaaa
      241 gagaagcact atgagaatac gattctccat agtgaccaag gctggcaata ccaacacgat
      301 tcttatcatc ggttcctaga gagtaaggga attcaagcat ccatgtcacg taagggcaac
      361 agcccagaca acggtatgat ggagtccttc tttgggattc tgaaatcgga aatgttttaa
      421 gtcgtttcag tcgcttaagc aattggaaca agctattgta gactatattg attactacaa
      481 caataagaaa attaagataa aactaaaagg acttagtcct gtgcaataca gaactaaatc
      541 cttcggataa attaattgtc taactttttg ggggcagtac ataagaacct tggtaatatg
      601 cgttttatta tggcaacatt tcccattttc tctatttcta atgacttact tcaactcctt
      661 acctcttgga aagaacaaca aagatatgaa ctagcaaagt ttggcatcct cagtaatcca
      721 gaacaatttg tttttacata tatcgacaca aaaggaaaca tcaacaagcc tttacatgcc
      781 gactatctga acaataaaat gaaaagcatt agaaagcgac ataaagaact gacacacgct
      841 acacctcaca aattacgcca tacaggcgca actctagcta aataagcagg aatgagctta
      901 gaagccattt ctgaagcact aacgcatagc gatacaggca caactcaaat ttatgtcaac
      961 acctctaatg tagttcctat gacagtaggt gaatttgctt taaagtctct aaaacaataa
     1021 ggtatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttagaattcg
     1081 atttgactgt cctgatcgat ttgtcctatt cttatttcat ttcgctataa aaataaggta
     1141 aactttgaga taaacttttc aaaaaaacac gaaaaaagca cccataaggt aaacttttga
     1201 gtgctttgaa acgttgatat aatcgtattg attaacgttt actaaattgt gatgctttac
     1261 gagctttctt aagacctggt ttcttacgtt caactttacg tgagtcacgt gtaagaagtc
     1321 ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg aagaagggca cgagcgatac
     1381 cgtgacggat agctcctgat tgaccagcgt atccaccacc tacaacgtta acgaaaacgt
     1441 cgtatgaacc tacagttgaa gtaactgcga atggttggtt gatgacaaga cgaaggtcag
     1501 cgtgtgggat gtactcttca acatcttttt tgttaacagt gattttacca gttcctggaa
     1561 caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt acctgcatat tgtgcttgtg
     1621 acatacttta ttgttccttt ccttagataa gtcctgaaat gtcaagaact tctggttgtt
     1681 gtgcagcgtg agtgtgctca gctccaacaa atactttcaa cttcatacct tgagcgcgtc
     1741 caagtgtatt gtgtggaagc atacctttaa ctgatttctc aatcaaacgt actgcatttt
     1801 tagaacgaag ttcacctgca gagatttgtt tcaatccacc tgggtggttt gagtgagtgt
     1861 agtagatttt atcagttgct tttttaccag tcaatttaac tttttcagca ttgataacaa
     1921 tcacgaagtc acctgtatca gtgtgtggtg taaatgttgg tttgtttttt ccgcgaagta
     1981 cgctagcaac tactgcagaa agacgtccaa gtggtacatc agttgcgtca actacgtacc
     2041 atttacgttc aacttggcct ggtttagcca taaatgttgt tttgttcatg atttctccta
     2101 tatatagttc gatttttgtt tacggtgatg ggtgttcctt cccatcgaaa agtatttgga
     2161 aggttccggg gcctttcaaa tggggtaaac aataccgcct actatcatac caaatttcac
     2221 ccctaaaagt caatagatat gaaaaatatt tttcggtaac ttctcaaagt aactgaaagt
     2281 tatataatca agttaatttg ggaatttacc tattaacttc ggtagatttt tgagaatttt
     2341 tttccttctt tttccttgta gttaaaatcc ttttcaaaaa atcacctttt cttgattttt
     2401 aatcctattt gctgtatgat aagggaaaag aaaggggaca gagatatggc ttttaccaat
     2461 acccacatgc gatctgctag ttttggcatt gttaccagct tgcctgatga catcattgac
     2521 tctttttggt atattatcga ccatttctta aaaaatgtct ttgaattgga agaagaactc
     2581 gagtttcaat tgcttaataa ccaaggaaag attaccttcc acttttcaag tcaacacctc
     2641 cctacagcca ttgattttga ctttaaccat cctttcgacc ctcgttatcc cccaagagta
     2701 ctggttttag acatggacgg tagagaaact atcctcctcc cagaagaaaa tgacctattt
     2761 taatacttaa tgaaaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta
     2821 cggtaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtataaaa actctagcct
     2881 tcagttgcaa gtaactgaaa actagagttt ttctattttt tc
//
LOCUS       DBEROT010000083         2589 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.83, whole genome shotgun sequence.
ACCESSION   DBEROT010000083 DBEROT010000000
VERSION     DBEROT010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.83"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            40..507
                     /locus_tag="ACL8CG_002112"
     CDS             40..507
                     /locus_tag="ACL8CG_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344635.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTIIVKKKKICYNEFKLRN
                     RKQKGVIMWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            517..723
                     /locus_tag="ACL8CG_002113"
     CDS             517..723
                     /locus_tag="ACL8CG_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1344636.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            723..920
                     /locus_tag="ACL8CG_002114"
     CDS             723..920
                     /locus_tag="ACL8CG_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344637.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            923..1657
                     /locus_tag="ACL8CG_002115"
     CDS             923..1657
                     /locus_tag="ACL8CG_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGS1344638.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NIIGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1669..2310
                     /locus_tag="ACL8CG_002116"
     CDS             1669..2310
                     /locus_tag="ACL8CG_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1344639.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            2328..2558
                     /locus_tag="ACL8CG_002117"
     CDS             2328..2558
                     /locus_tag="ACL8CG_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1344640.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          757 a          422 c          531 g          879 t
ORIGIN      
        1 gaagctgacg tggtttgaag agattttaga agagtattaa tgatagataa agtggtcagg
       61 aacttactcc tgaccttttt cttttgcaaa atgacaaaaa tcataaactt tttgacaact
      121 ataattgtca aaaagaaaaa gatatgttac aatgaattca agttaagaaa taggaagcag
      181 aaaggagtta taatgtgggt actaggattt atactattta tgattttctt ttattctaat
      241 aattctaaaa aaatcaagaa actagagaat aaaatcaaaa aacttgagcg aaaagagaaa
      301 ggaaacgcag aaatgtcgag attattacaa gaaatgattg gaaaggaacc aattataacg
      361 ggagtgtata ttgggccaga taactgggaa gttgtggatg ttgatgagga atgggtcaaa
      421 ctacgtagtg ttgataatac gggaaaagaa aaattcaagt tgcaacgtat tgaagatatc
      481 caaaccgttg aatttgacgg agagtaggtg tgtaacgtgc aactaaaaaa tcgtctaaaa
      541 gagcttcgag ctcgcgatgg tctcaatcaa accgacctag ccaaactggc aggggtttcc
      601 agacagacca ttagcctact agaacgggat gagtacaccc catccattat cattgccctg
      661 aaaatatctc aaattttcaa cgaaacagtc gaatcggtat ttcgtttgga ggaggacgag
      721 tgatgaacaa gtataaagtg atttattatg tagtggtcat agctttatta gtcagcgtat
      781 ttctactgat tgggatggac ctaagctggt ttaatcccta tcaaagcgac caatttgttt
      841 gggtctactt tgctctcatc ccagtaactg aatggattga aaagaaatcc aaaaatctag
      901 caagtgaaaa aggagaatga atatgaaaaa gaaacgtaga ttgttatttt tgatgtctat
      961 tgtcttgggg gggttcttgg gcatgtttgt agggatgttt aaggcacgtg tcgaatccca
     1021 cgaaattatt ttagatgtaa aagccttgat gccatggata tcagctattt gtttactgat
     1081 aggtttcatt agtatgtttt tgactttcaa tttcttaaag aaaagcagaa aatttcattc
     1141 cttgtatcaa gaggaaatgg atgacgatct gaatgaaacc tattatgtgc aaatgtatcg
     1201 gaatcttgag tttggaacca ttgcttttaa tattataggt gtagcgattc cattggctat
     1261 ttttatttca ttaagtgagg tgattatatt gcatacaaac cctcaaacat ttttcctttc
     1321 tttcttactc tttgtggtat tcttagtcgc tcaaaaatct ctttttaaaa ccattgcgat
     1381 tgttcgtcag tttgatttgg aatttttcgc tacaccaaag gatgtcttga actatataaa
     1441 ttcttatgat gaaggggagc gtcaggctaa tttggaacag agttttcgaa ttttattcca
     1501 attacaccaa tatgtcttac cagccttata tatttttctt attatcattt ctttcttgac
     1561 aggagagatt cagttactag ctttcttgct tgtaggagcc atccatgttt atatcaatgt
     1621 gatgcagtta cctatggtaa aacgttattt caaataaagg agttatctat gaaattactt
     1681 aaaaaccttg gctggattct tctagccctt ctatcctttt tatttatcta tggctttatt
     1741 caggggctcg cgactgcgtc gcttgcttta ggcgcttcac cctatgctgt tactctactc
     1801 tatgtggcct tggctggagt atatgtgtac ggcatttaca aatggtatca gaaggctcct
     1861 gttcatattg agaagagcgg ctttaatcga tttatttggc ttcctgtctt ggtttggttc
     1921 ttatctctgg tcgttcaatt cttcttgcca gatgatcctt cagtaaatca gcaaatagcg
     1981 acagacttga ccttgtctca accacttttc tcattctttg ctgtggttat ttttgctcct
     2041 ttgacggaag agattgtttt tagagggatg ttagcacgct atctctttcc taagcaggac
     2101 aatagtaaac gaaccctgat ttttcttctg gtatctagtc ttctatttgc cttgattcat
     2161 tttccaggtg atgtgcaaca attttttgtc tattttagcc ttggttttag tttgggtttg
     2221 gcttacgtta gcagaaaagg tctggtctac agtatttctc ttcacgcttt gaataattta
     2281 gtcggctttt tgatgattct catgctataa tagagtcagg aggtcacatg aaacgagtaa
     2341 ttttattagc agtgattcag gcagtcgttc tatttttcat cattggagcg ctagcttatg
     2401 ccttcaaagg cgatttcttc tataactatc tagcagttgt ctttgctcct attgcaggtg
     2461 tactgcgttt tgggacggct tacataacgg aaattgtctt gcctcgaaag gcagccgaaa
     2521 tcgctgaaaa gcgtaaagca ggcaaaaatt caaaataaaa gagtccggtg aagttcatcg
     2581 gatttttgt
//
LOCUS       DBEROT010000084         2223 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.84, whole genome shotgun sequence.
ACCESSION   DBEROT010000084 DBEROT010000000
VERSION     DBEROT010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.84"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..261
                     /locus_tag="ACL8CG_002118"
     CDS             <1..261
                     /locus_tag="ACL8CG_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1344641.1"
                     /translation="TDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNS
                     SSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            299..604
                     /locus_tag="ACL8CG_002119"
     CDS             299..604
                     /locus_tag="ACL8CG_002119"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1344642.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            652..2127
                     /locus_tag="ACL8CG_002120"
     CDS             652..2127
                     /locus_tag="ACL8CG_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGS1344643.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          653 a          439 c          441 g          690 t
ORIGIN      
        1 acagatattg ttcataatct agctgagaaa gtggtggttg ttcgattaga aaaaccagta
       61 acttttcaca atatgatagc tcctgataag gaagtagaag tatccttgct cttctttatc
      121 atcaataact caagttcaag tcaaacaaat attctggctc agttgatgga ctttttcaca
      181 ggaaatggac atcttgaaga cctatcaaaa atttccgaac cagaaaaact ttatgcttac
      241 attgctgaag caaccgctta atcttgtcta ttaaaaaata aaatcggagg aaatctaaat
      301 gattaaaatt cttgctgcct gcggtgcagg tgttaactca agtcaccaaa ttaaaagtgc
      361 tctagaagaa gaactttcaa accgtggtta tgatgttcac tgtgatgcag tcatggtgaa
      421 agatgtaaac gaagacctta tgaaaggtta cgatatcttt acaccaatcg ctgcaacaga
      481 ccttggtttt gaaccaggta tcccagttat cgaagctgga ccaatcttat tccgtatccc
      541 agcaatgagc gctccagtat ttgacaatat tgaagcagct attaaagaac acggattaag
      601 ctaattctaa tttgttaaca ttcatataac ataaaaaagg gaggaactgt tatggatgca
      661 atctttgacc taatcggaaa ggttttcaat cccatcttag aaatgggtgg acctgtcatc
      721 atgttaatca ttttgacagt attggcttta ctttttggag tgaaattctc caaagcgctt
      781 gaaggtggta tcaaacttgc catcgctctt acaggtatcg gtgctatcat cggtatgcta
      841 aatggtgctt tctcagcatc acttgcaaaa ttcgttgaaa acactggtat acaattgagt
      901 attaccgacg ttggttgggc accacttgca acaatcactt ggggttctgc ttggacactt
      961 tacttcttgc tcatcatgtt gattgtcaac gtagtgatgc ttgctatgaa gaaaaccgat
     1021 acacttgatg tcgatatctt tgatatctgg cacttgtcta tcacaggtct tttgattaaa
     1081 tggtatgctg ataacaatgg tgtgagtcaa ggggtttcac tcttgattgc tacagcagct
     1141 atcgttcttg tcggtgtgtt gaaaattatc aactctgact tgatgaaacc tacatttgat
     1201 gaccttctta acgccccaag ttcatcacca atgacatcaa ctcacatgaa ctacatgatg
     1261 aacccagtta tcatggtttt ggataagatt tttgaaaaat tcttcccagg ccttgataaa
     1321 tatgactttg atgctgctaa attgaacaag aaaatcggtt tctggggatc taaattcttc
     1381 atcggtttca tccttggtat cgttatcggt attatgggaa ctccacatcc aattgcaggt
     1441 gttgcagatg cagataaatg gcgtcttgtt atcaaaggat ggttgtctct tggtttgact
     1501 gccggtgtat ctttggaact cttctcactt atcggttcat ggttcatcgc agccgtagaa
     1561 ccactatcac aaggtattac aaacgttgct actaaacgtc ttcaaggacg taaattcaat
     1621 atcggtcttg actggccatt catcgctggt cgtgctgaaa tctgggcttg tgccaacgta
     1681 cttgcaccaa tcatgttgat tgaagcagtg cttctttcaa aagttggaaa tggtatcttg
     1741 ccacttgcag gtatcatcgc tatgggtgtt actccagctc tcttggttgt aactcgtggt
     1801 aaattgctcc gtatgattat cttcggaaca ctcttgttgc cactcttcct tctttcaggt
     1861 acacttattg caccatttgc aacagaactt gctaaaggtg taggtgcctt cccagaaggt
     1921 gtgagccaaa ctcaattgat tactcactct actcttgaag gaccaatcga aaaacttctt
     1981 ggttggacaa ttggtaacac tacaactggt gatatcaaag caatccttgg tgcagtagcc
     2041 ttccttgtat tctatatcgg tatctttgct tggtacagaa aacaaatgat caaacgtaac
     2101 gaagagtacg cagcaaaagc aaaataatgc gctcctataa aatataaact caatgaaaat
     2161 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cacagttttg aggttgtaga
     2221 taa
//
LOCUS       DBEROT010000085         2014 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.85, whole genome shotgun sequence.
ACCESSION   DBEROT010000085 DBEROT010000000
VERSION     DBEROT010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.85"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1409)
                     /gene="pcpA"
                     /locus_tag="ACL8CG_002121"
     CDS             complement(<1..1409)
                     /gene="pcpA"
                     /locus_tag="ACL8CG_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGS1344644.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNDGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKG"
     gene            1744..1860
                     /locus_tag="ACL8CG_002122"
                     /pseudo
     CDS             1744..1860
                     /locus_tag="ACL8CG_002122"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          674 a          323 c          285 g          732 t
ORIGIN      
        1 cctttgtctt taacccaacc aactactccc tgattagaat tctttttagg tttagctaca
       61 tcagtttctt gttttatatt atctactttt tcaacaatga tatcattact agtagataaa
      121 tttgatttaa gaacatcttt tatatgttct gatgttacat agaacttaac agtttcagga
      181 attgcaaatg tatctttttt cacagaaaac tctgtacttt tattcttaat atgaatttcc
      241 tttaatgaat ctaagacgcc acttaggaag aaggacggca atgagttgat attattacca
      301 attgttaaac tttttaattt tggtaaaccg ttcataacgt gtttaccaaa atttttaaca
      361 ttatctggta atataagttc ttttaattct aaattaccgt aaaaggctaa acgttcaata
      421 gtttctaaac tatttggtaa gctaatttct tcaagtttaa tcgcatctgc aaatgcaaaa
      481 gtaccgattt tttctaaacc atcattcaat tcgagttttt tcaagtaaga atttttatta
      541 aacgaatatg atgcaagttc ttttgtctcc ttaggcgttt tataactttc gtcatttttt
      601 tgacttggat aataaattaa ttgagtttta tcttttgaaa acaaaacacc atcaactgag
      661 gcaaacgatt catttccttc ttcaacatca acatgtttta agctagtagt gagtctaaat
      721 agattacttc ctaatgtttt aaccgatttt ggtaatgtta gtttctctaa atttgataaa
      781 ttagcaaaag cctcatgtga tattaattct aattttgaac ttgaggaaaa ggttagcttt
      841 ttcaattttt gactaaaaga aaatgcactt gttccaatat attctagaga tgcaggcaat
      901 tcaatctctt ctaattcaga aaaatcaaaa gctctatctt caattttctc cagctgactg
      961 cctttgtcaa aaataatagt tttagcttta cttccatgga agcctttttt ttgtattttt
     1021 tttatgcttg atgggatagt aatagagcta ggatagtaga caattctacc tgtttcatct
     1081 ggataataac taaaagcttg actagctact tcagtaacgg taaatacttt atcacctact
     1141 gtgatttttg taggaatcgt gaatggtttt ccatcttgac cagcttcaaa ctctacagga
     1201 gtaactccat tacccacttg aacagttcct atgttacctt ctacagttag aaccttatat
     1261 ttgatattat tttgttgaat aatacttcca actttagtct ctttgattac ttccgaacta
     1321 ggagtatctg ctaggattgg ttcattaggg acatatgctg ctaaaataac cgcagctgta
     1381 gttaatgata atattgtagt ttttttcatt taaatttcct tacatattta ttttctaata
     1441 gatataaaat tataactttg ctagccgttg ttataaaaag ttttattcaa tcattatcta
     1501 gtagaataga gtagtacatt ttataaattg tcatctctct ataaacacag tatatcattt
     1561 ttaaatttta agtcaaggaa aattaaccca ctttaatttc ttttttaacc cgggttaaaa
     1621 aagaaattaa agtgggttaa aaaagaaatt aactgagtaa aaactctcga aattcaatta
     1681 gctatattat cactcaactt gaacaaatac cagaaccaca aaaaacagat gtaaaggaaa
     1741 aatatggact taaaatttga aggggttgat ttagaataca aaaaagctaa aaacaatctt
     1801 ccagagtctt tctgggaaac ctactcagca tttgcaaata caaatggcgg gaaaataatt
     1861 ctcgggatag atgaaaaaaa aacattgacc cctaccaagg agtcaataga cttcctgcga
     1921 aacaaaatta tgaagcaagt aaacaactaa ccgatgcacg atttaagcgt cttgttggtg
     1981 ttcagcgcac cacttttgaa gagatgttag ctgt
//
LOCUS       DBEROT010000086         1686 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.86, whole genome shotgun sequence.
ACCESSION   DBEROT010000086 DBEROT010000000
VERSION     DBEROT010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.86"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(367..1347)
                     /locus_tag="ACL8CG_002123"
     CDS             complement(367..1347)
                     /locus_tag="ACL8CG_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGS1344645.1"
                     /translation="MKNSALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT          503 a          364 c          312 g          507 t
ORIGIN      
        1 aaggcgaagc tgacgtggtt tgaagagatt tttgaaaagt attaacacct acagacaagc
       61 ctgacgatag caagaactac cctactcgat aggtatcggc ttttgctttc tgaaaaaaat
      121 tattttaagc aatttgacaa atctagcaac aaaaaattct ataaatacaa tagattgaaa
      181 ctagaatagt acacctttgc ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
      241 gatttgtcct gttcttgttt catttcacta tatttccatg ataaaacgca tagtatcaag
      301 ttttcttaat cccctgatac tatgcgtgtt tgtaattttt aagattttgt gcttagagtc
      361 gactccttat tttagatatt taaaaggaat ctcacttcca cagagccagt tgtagacttg
      421 gtcattaaca aatacattca tggcttcgtg agcatactca ggcatgatac gataggtttt
      481 atcgcaggtc agacgattat aaatcgcaaa ctgggtaatg ggatagcaaa catcgtcgtc
      541 caagcccgta atcatcttaa cctcaccttg gatacgatgg gcaagatttt tgacatcgat
      601 ataggcaagg gtcgccatga tttcctcctc tgtttcatgg aaggggtcgt gaaacttgaa
      661 ataacggaaa agttcgtcgt aagcctcgct agtattacca atctcaatca cccgtctgaa
      721 gtctgacaag aagggataaa tggcaactgt tttctgaatt cgaggattga gcgctgctgc
      781 aactagagct agagcccctc cttgtgaggc accatagcta gaaagacgct tctcatcaac
      841 ctgagacaga ctagcaacaa tttcgaccaa ctggtaaata tccagataaa catccttata
      901 aaagaggtgg tcccgacctt ccatagcacc acggataata tgccccttca cggtatttcc
      961 taaaggagaa cgcaagccgt cttgtgagta acctgactgg ccccgcacat ccatggaaac
     1021 aacaccgtaa ccagctacgg tgaagcccag catgtcggcc cagtcccagc cacgtcccat
     1081 ataaccatga aaatggaaga ttaatggaac cttctcctca ctctttggaa gaacaatgcg
     1141 tgcatagacc tttccttcct tgcttccttc aaatgttaac tcatagcact tgacttgagg
     1201 aatgtggaaa tctctttcct ccaagtggta ggatggaagc gtggaaacat ttttcacttc
     1261 cccatcccag aaagcatcaa agtcttccgg aacctcatcc cttcctctat aggtcttaat
     1321 ttcttctagc aaagctgaat ttttcatagc atgctccttt tattttgtaa tcgttaccac
     1381 aactgtagca tatctatgta atcaatgcaa gaaagaaggg taaatagaaa gtgaatttag
     1441 attctttact tttaggatga tgggctgaaa gtagttttag aaacgaaaaa agagcatttc
     1501 gctctctctt ctgtttatac tagttttttg cttccttctt ttggaaagtg atttggtaat
     1561 ttactttaat cgttactgtc atatgagagt cctcgtttct ttttgatgac tttagtataa
     1621 gagccaaacc taaaaactag cttaatactc ttcgaaaatc tcttcaaacc acgtcagcgt
     1681 cgcctt
//
LOCUS       DBEROT010000087         1633 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.87, whole genome shotgun sequence.
ACCESSION   DBEROT010000087 DBEROT010000000
VERSION     DBEROT010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.87"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..292)
                     /locus_tag="ACL8CG_002124"
     CDS             complement(<1..292)
                     /locus_tag="ACL8CG_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HGS1344646.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAAVFGIHESNLIRRSQWVEVTLVQSG"
     gene            complement(385..1043)
                     /locus_tag="ACL8CG_002125"
                     /pseudo
     CDS             complement(385..1043)
                     /locus_tag="ACL8CG_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(1150..1587)
                     /locus_tag="ACL8CG_002126"
                     /pseudo
     CDS             complement(1150..1587)
                     /locus_tag="ACL8CG_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT          464 a          357 c          309 g          503 t
ORIGIN      
        1 caccactttg aacaagagtt acttcaaccc attggctccg acggattaag ttgctttcgt
       61 gaataccaaa aacagccgca atttgttcat aagttcgata ttctcgcaca tattgaagag
      121 tggccataag aaggtcttct agacttaatt taggttttcg tccacctttt gcgtgtttaa
      181 gttgataagc tgtttttaat acagctaaca tctcttcaaa agtcgtgcgt tgaacaccaa
      241 caagacgctt aaatcgtgca tcggttagtt gtttacttgc ttcatcattc atagaactat
      301 tataccatat tttgtttcgc aggaagtcta ttgaaaaatc tccagactgg agaactcacg
      361 gatagttcct aatctggaga tttcttattt gcacttttct tgtacaactt tagtccatgg
      421 taaataagcc tctaaaacct ctttgtttac gagagtttcc tcgtttggaa gacattctag
      481 aagataggat agatatttct cgctatttaa ttgatgacgt ttagctgttt ccaacaaact
      541 cataataata gctcttgctt tagctccttc aaaactttga gaaaataacc accctcgctt
      601 ttttaaactg agcttaggct aaaagagtcc actggactct tttactccgt cccataacca
      661 atgatttaat ggcgcgttca gctagattat tggaaaggac cagatgtccg tctttcaaaa
      721 tggtcttaaa ggtttcttca tacttgaggc tgtattcaat tgcccttcct agttttgaac
      781 ctgctaaaac tgactgacgc cggcactaag caaagaagtc ttccattaag ggctggagat
      841 gttcttgacg tttctgtagt cgttcatcag ctggcaaagc ctcccagtct ctttccaagg
      901 aaaataactg atcacaataa gctaaacctt tagctcctaa ggatgattta tccgcttgct
      961 tgggggggcg cttcaaaaaa cttccttctc acatgcgccc aacatccaac aagttcagct
     1021 tcttccagtt gacgataagc agacgagcgg ttcgaagttt accaagctta gcgtcgcctt
     1081 gctcctaaac cttggactgc tatcgcatag gcagaactag aggactaaag tcctaagtta
     1141 ctgccgcaaa atatcacaat gcacatagcc agaataatct cctaggaatt cttgtactac
     1201 tgaaccactt cgacactgat catggtggta aagcgtaatc ccttgtttct ctgctttacc
     1261 tgacaaaaaa gtccaatagt aagtcagctg actatcactc tctagcaccc tataagaagt
     1321 ttcatccgca tgaagtaagg gctgagtcaa tagtctctct cgcaagaggt tataaagggg
     1381 ctccaaatag tattgactcg ccttgatatg ccaattagag atttccttac gtgtgattgg
     1441 taaacccatc ctagcccaat cttcttcttg gcgataattg ggtaccttca gattaaactt
     1501 ctgatggatg gtgtgagcga taatagaagc tgagccaaag ttatgcgcta aaggggcttt
     1561 aggaatagga gatttcacaa gcttatccag atgattatct tttactcgtt atggacaatg
     1621 ctatatggca taa
//
LOCUS       DBEROT010000088         1512 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.88, whole genome shotgun sequence.
ACCESSION   DBEROT010000088 DBEROT010000000
VERSION     DBEROT010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.88"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            68..504
                     /locus_tag="ACL8CG_002127"
                     /pseudo
     CDS             68..504
                     /locus_tag="ACL8CG_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            669..968
                     /locus_tag="ACL8CG_002128"
     CDS             669..968
                     /locus_tag="ACL8CG_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGS1344647.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1229..1465
                     /gene="tnpB"
                     /locus_tag="ACL8CG_002129"
     CDS             1229..1465
                     /gene="tnpB"
                     /locus_tag="ACL8CG_002129"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS1344648.1"
                     /translation="MMILLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLT"
BASE COUNT          518 a          297 c          268 g          429 t
ORIGIN      
        1 acattgtgta ctatttttgg ttcatttcac tataataata acgatactag ataatgagga
       61 aaatgcaatg gcaaacccaa ctttcggaga aaaaagcgaa tacagactat attgctcgct
      121 atggcgtata tgcagttatc cctaatcctg aacaaaaaca aattgttctt gttcaagaac
      181 caaatggtgc ttggttccta ccatgtggag aaattgaagc aggtgaaaat catcaggaag
      241 ccctaaagcg tgagttgatt gaagagcttg gtttcacagc agaaattggt acctattacg
      301 gacaagctga cgaatatttc tattctcgtc atcgtgatac ctactactcc aatcctgcct
      361 acctctatga agcaactcct aaagccacta gaaaacttta atcatattgc ctggttccct
      421 attgacgagg ctatcaaaaa ccttaaacgt ggtagccata aatgggccat tgaatcttgg
      481 aaaaaacagc ataagattga ctaatactct tcgaaaataa aattcaaacc acgtcagcgt
      541 cgccttaccg tactcaagta tagcctgcgg ctagcttcct agtttgctct tttattttca
      601 ttgagtataa atcaagcgac tttattcaaa aagtgctata atagaattag aaaatcggag
      661 gaaatattat gaagcttatc aatacgacaa actcacactc gcaacttgta aaaagtcagc
      721 tagaaagtac cgatgcaacc cttgttgagg tttattctgc agggaataca gatgttattt
      781 ttacccaagc tccgcttcac tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg
      841 agcctgaaat cgaaaccatt caagaatttt tcttgaaacg taaaattgat aagacctctg
      901 ttgatgaagc caatatcaag acactctact cagagaaatt aattggaatt tcaatcccaa
      961 tcaagtaaga aaattgagta aaaactcgat ttgagagaaa gtccaataag tctttccata
     1021 acaaaacgca tagtaacaag agtttctaca cccactatta tacgttttta tcattttgaa
     1081 atctgctgct aatcaatgaa gaagcaaaga tcaaactagg cagctagtta caagttacgt
     1141 aagcgcgtca taacaaggta tctatcctaa ttccccaact tccagtatac tagataaaaa
     1201 ataattatca gaggaaaagt attgtactat gatgattcta ctaagtgatt taggtcaagt
     1261 tcaccttgtt tgtggcaaga cagatatgag gcagggaata gactcattag cctatgtagt
     1321 taaaacccac tttgaattgg atcctttctc aggtcaagtt tttctctttt gtggtggacg
     1381 taaagaccgc tttaaagccc tttactggga tggtcaagga ttttggctac tatataaacg
     1441 ctttgagaac ggaaaactga cttgaccaag tacagaaaag gatgtcaaag ctctcgcacc
     1501 tgaacaagta ga
//
LOCUS       DBEROT010000089         1322 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.89, whole genome shotgun sequence.
ACCESSION   DBEROT010000089 DBEROT010000000
VERSION     DBEROT010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.89"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            25..>1322
                     /locus_tag="ACL8CG_002130"
     CDS             25..>1322
                     /locus_tag="ACL8CG_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGS1344649.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSESEVSNQKSSVATSTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKG"
BASE COUNT          495 a          203 c          261 g          363 t
ORIGIN      
        1 taaattttat ttcaaggagg aataatggaa aagtattttg gtgaaaaaca agagcgtttt
       61 tcatttagaa aattatcagt aggacttgta tctgcaacga tttcaagttt attttttatg
      121 tctgtattag ctagttcatc tgtggatgct caagaaactg cgggagttca ctataaatat
      181 gtggcagatt cagagctatc atcagaagaa aagaagcagc ttgtctatga tattccgaca
      241 tacgtggaga atgatgatga aacttattat cttgtttata agttaaattc tcaaaatcaa
      301 ctggcggaat taccaaatac tggaagcaag aatgagaggc aagccctagt tgctggtgct
      361 agcttagctg ctctgggaat tttaattttt gctgtttcca agaaaaaggt taagaataaa
      421 acggtattac atttagtatt ggttgcagga ataggaaatg gtgtcttagt ttcagtccat
      481 gctttagaaa atcatctttt gctaaattac aatacggact atgaattgac ctctggagaa
      541 aaattacctc ttcctaaaga gatttcaggt tacacttata ttggatatat caaagaggga
      601 aaaacgactt ctgagtctga agtaagtaat caaaagagtt cagttgccac ttctacaaaa
      661 caacaaaagg tggattataa tgttacacca aattttgtag accatccatc aacagtacaa
      721 gctattcagg aacaaacacc tgtttcttca actaagccga cagaagttca agtagttgaa
      781 aaacctttct ctactgaatt aatcaatcca agaaaagaag agaaacaatc ttcagattct
      841 caagaacaat tagccgaaca taagaatcta gaaacgaaga aagaggagaa gatttctcca
      901 aaagaaaaga ctggggtaaa tacattaaat ccacaggatg aagttttatc aggtcaattg
      961 aacaaacctg aactcttata tcgtgaggaa actatagaga caaaaataga ttttcaagaa
     1021 gaaattcaag aaaatcctga tttagctgaa ggaactgtaa gagtaaaaca agaaggtaaa
     1081 ttaggtaaga aagttgaaat cgtcagaata ttctctgtaa acaaggaaga agtttcgcga
     1141 gaaattgttt caacttcaac gactgcgcct agtccaagaa tagtcgaaaa aggtactaaa
     1201 aaaactcaag ttataaagga acaacctgag actggtgtag aacataagga cgtacagtct
     1261 ggagctattg ttgaacccgc aattcagcct gagttgcccg aagctgtagt aagtgataaa
     1321 gg
//
LOCUS       DBEROT010000090         1186 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.90, whole genome shotgun sequence.
ACCESSION   DBEROT010000090 DBEROT010000000
VERSION     DBEROT010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.90"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>1186
                     /gene="phtD"
                     /locus_tag="ACL8CG_002131"
     CDS             <1..>1186
                     /gene="phtD"
                     /locus_tag="ACL8CG_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGS1344650.1"
                     /translation="LIFDPAQITSRTARGVAVPHGNHYHFIPYSQMSELEERIARIIP
                     LRYRSNHWVPDSRPEQPSPQSTPEPSPSPQSAPNPQPAPSNPIDEKLVKEAVRKVGDG
                     YVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAY
                     DLLARIHQDLLDNKGRQVDFEALDNLLERLKDVPSDKVKLVDDILAFLAPIRHPERLG
                     KPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDS
                     LSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNL
                     QYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERP
                     HS"
BASE COUNT          379 a          262 c          246 g          299 t
ORIGIN      
        1 gccttatttt cgacccagcg caaatcacaa gtcgaaccgc cagaggtgta gctgtccctc
       61 atggtaacca ttaccacttt atcccttact ctcaaatgtc tgaattggaa gaacgaattg
      121 ctcgtattat tccccttcgt tatcgttcaa accattgggt accagattca agaccagaac
      181 aaccaagtcc acaatcgact ccagaaccta gtccaagtcc gcaatctgca ccaaatcctc
      241 aaccagctcc aagcaatcca attgatgaga aattggtcaa agaagctgtt cgaaaagtag
      301 gcgatggtta tgtctttgag aagaatggag tttctcgtta tatcccagcc aagaatcttt
      361 cagcagaaac agcagcaggc attgatagca aactggccaa gcaggaaagt ttatctcata
      421 agctaggagc taagaaaact gacctcccat ctagtgatcg agaattttac aataaggctt
      481 atgacttact agcaagaatt caccaagatt tacttgataa taaaggtcga caagttgatt
      541 ttgaggcttt ggataacctg ttggaacgac tcaaggatgt cccaagtgat aaagtcaagt
      601 tagtggatga tattcttgcc ttcttagctc cgattcgtca tccagaacgt ttaggaaaac
      661 caaatgcgca aattacctac actgatgatg agattcaagt agccaagttg gcaggcaagt
      721 acacaacaga agacggttat atctttgatc ctcgtgatat aaccagtgat gagggggatg
      781 cctatgtaac tccacatatg acccatagcc actggattaa aaaagatagt ttgtctgaag
      841 ctgagagagc ggcagcccag gcttatgcta aagagaaagg tttgacccct ccttcgacag
      901 accatcagga ttcaggaaat actgaggcaa aaggagcaga agctatctac aaccgcgtga
      961 aagcagctaa gaaggtgcca cttgatcgta tgccttacaa tcttcaatat actgtagaag
     1021 tcaaaaacgg tagtttaatc atacctcatt atgaccatta ccataacatc aaatttgagt
     1081 ggtttgacga aggcctttat gaggcaccta aggggtatac tcttgaggat cttttggcga
     1141 ctgtcaagta ctatgtcgaa catccaaacg aacgtccgca ttcaga
//
LOCUS       DBEROT010000091         1088 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.91, whole genome shotgun sequence.
ACCESSION   DBEROT010000091 DBEROT010000000
VERSION     DBEROT010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.91"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            10..>1088
                     /locus_tag="ACL8CG_002132"
     CDS             10..>1088
                     /locus_tag="ACL8CG_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1344651.1"
                     /translation="MGQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     IEDNLKQVHPIFQTVFKTFLKNKEK"
BASE COUNT          355 a          231 c          174 g          328 t
ORIGIN      
        1 aagattcata tgggacaatt acattttatc acaaaactac tcgatatcaa agacacaaat
       61 atccaaatta tagatgtcgt caatagggat tcacacaaag aaatcatcgc caaactggac
      121 tacgacgccc catcttgccc tgattgtgga agtctaatga agaaatatga ctttcaaaaa
      181 ccgtctaaga tcccttacct cgaaacaact ggtatgcctt ctagaattct ccttagaaaa
      241 cgccgtttca agtgctatca ctgttcaaaa atgatggttg ctgagactcc cctggtaaag
      301 aaaaatcacc aaatccctcg tatcatcaac caaaaaattg ctcaaaagtt aattgaaaaa
      361 atttctatga ctgatattgc ccatcagctg gccatttcaa cttcaactgt cattcgcaag
      421 ctcaatgact ttcactttga gcatgatttt tctcggcttc caaagattat gtcttgggat
      481 gagtatgcct tcactaaggg aaagatgagt ttcattgcgc aagattttga taatcttaat
      541 attatcactg ttcttgaagg cagaacacaa gctgtcatcc gaaatcactt tcttcgctac
      601 gatagagccg ttcgttgtca agtgaaaatc attacgatgg atatgtttag tccttactat
      661 gacttggcta aacagctttt tccgtgtgct aaaatcgttc tagatcgttt ccatattatc
      721 caacatctca gccgtgccat gagtcgtttt cgtgttcaaa ttatgaatca gtttgaacga
      781 aaatctcatg aatacaaggc tatcaagcgt tactggaaac tcatccaaca ggatagtcgt
      841 aaattgagcg ataaacgttt ttatcgccct acttttcgca tgcacttaac aaataaagaa
      901 attcttgaca agattttaag ctattcagaa gacttgaaac accactatca gatctatcaa
      961 ctcttacttt ttcactttca gaacaaagac cctgagaaat ttttcggact cattgaggac
     1021 aatctgaagc aggttcatcc tatttttcag actgtcttta aaacctttct aaagaacaaa
     1081 gagaaaat
//
LOCUS       DBEROT010000092          881 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.92, whole genome shotgun sequence.
ACCESSION   DBEROT010000092 DBEROT010000000
VERSION     DBEROT010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.92"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(8..81)
                     /locus_tag="ACL8CG_002133"
     tRNA            complement(8..81)
                     /locus_tag="ACL8CG_002133"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45..47),aa:Ile,seq:cat)
     gene            complement(95..168)
                     /locus_tag="ACL8CG_002134"
     tRNA            complement(95..168)
                     /locus_tag="ACL8CG_002134"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(132..134),aa:Met,seq:cat)
     gene            complement(174..247)
                     /locus_tag="ACL8CG_002135"
     tRNA            complement(174..247)
                     /locus_tag="ACL8CG_002135"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(211..213),aa:Pro,seq:tgg)
     gene            complement(263..336)
                     /locus_tag="ACL8CG_002136"
     tRNA            complement(263..336)
                     /locus_tag="ACL8CG_002136"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Arg,seq:acg)
     gene            complement(346..431)
                     /locus_tag="ACL8CG_002137"
     tRNA            complement(346..431)
                     /locus_tag="ACL8CG_002137"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Leu,seq:taa)
     gene            complement(439..510)
                     /locus_tag="ACL8CG_002138"
     tRNA            complement(439..510)
                     /locus_tag="ACL8CG_002138"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:gcc)
     gene            complement(533..605)
                     /locus_tag="ACL8CG_002139"
     tRNA            complement(533..605)
                     /locus_tag="ACL8CG_002139"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Thr,seq:tgt)
     gene            complement(624..705)
                     /locus_tag="ACL8CG_002140"
     tRNA            complement(624..705)
                     /locus_tag="ACL8CG_002140"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Leu,seq:tag)
     gene            complement(711..783)
                     /locus_tag="ACL8CG_002141"
     tRNA            complement(711..783)
                     /locus_tag="ACL8CG_002141"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(748..750),aa:Lys,seq:ttt)
     gene            complement(808..880)
                     /locus_tag="ACL8CG_002142"
     tRNA            complement(808..880)
                     /locus_tag="ACL8CG_002142"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(845..847),aa:Asp,seq:gtc)
BASE COUNT          232 a          257 c          199 g          193 t
ORIGIN      
        1 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
       61 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      121 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      181 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      241 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      301 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      361 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      421 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      481 ggtggtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      541 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      601 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      661 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      721 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga
      781 gtctaaaata acttgcgtta ccttaaacgg tcccgacggg aatcgaaccc gcgatcttcg
      841 ccgtgacagg gcgacgtgat aaccgctaca ctacgggacc t
//
LOCUS       DBEROT010000093          759 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.93, whole genome shotgun sequence.
ACCESSION   DBEROT010000093 DBEROT010000000
VERSION     DBEROT010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.93"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..416
                     /locus_tag="ACL8CG_002143"
     CDS             <1..416
                     /locus_tag="ACL8CG_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1344652.1"
                     /translation="REYGRSLKGQLRRGKVSGRRYQRISLVAGLTNGELIAPMTYEET
                     MTSDFFEAWFQKFLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEY
                     NPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            316..>759
                     /locus_tag="ACL8CG_002144"
     CDS             316..>759
                     /locus_tag="ACL8CG_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1344653.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCPALVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDKVDHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
BASE COUNT          259 a          159 c          130 g          211 t
ORIGIN      
        1 atcgagaata tggtcgctca ttaaaaggtc agttaagaag aggcaaagta tctggaagaa
       61 gatatcagag gatttctttg gttgcaggtc taacaaatgg tgaattaatc gctccaatga
      121 cttacgaaga gacgatgacg agcgactttt ttgaagcttg gtttcagaag tttctcttac
      181 caacattaac cacaccatcg gttattatta tggataatgc aagattccat agaatgggta
      241 agttagaact cttgtgtgaa gagtttgggc ataaactttt acctcttcct ccctactcac
      301 ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc aaaaaggtat
      361 taccaagttg caataccttt tacgaggctc ttttgtcctg ctcttgtttc aattgactat
      421 ataaattgtc taagcgaaac aaccgataag aattggcaca aaagcgaccg tatttttgtt
      481 accaatacag gaaaaccagt tcatagttct atcttgagca agtctctcca gcgagcaaac
      541 gaacgcctta aaaaaccaat tcccaaacat ctgtcccctc acatcttcag acacaccact
      601 attagcatct tatcagaaaa taaaattcct ttaaaaacaa tcacggacaa ggttgatcat
      661 tccgactctg aagtcactac ttccatctac acccacgtca caaagaacat gaaagatgaa
      721 gcaatcaatg tactggataa agttatgaaa aagattttt
//
LOCUS       DBEROT010000094          677 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.94, whole genome shotgun sequence.
ACCESSION   DBEROT010000094 DBEROT010000000
VERSION     DBEROT010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.94"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..677
                     /locus_tag="ACL8CG_002145"
                     /pseudo
     CDS             1..677
                     /locus_tag="ACL8CG_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          194 a          149 c          127 g          207 t
ORIGIN      
        1 gacgccccat cttgccctga gtgcggaaac caattgaaga aatatgactt tcaaaaaccg
       61 tctaagatcc cttacctcga aacaactggt atgcctacta gaattctcct tagaaaacgc
      121 cgtttcaagt gctatcactg ttcaaaaatg atggtcgctg aaacttctat cgtcaagaag
      181 aatcatcaaa ttcctcgtat tatcaaccaa aaaattgcgc aaaagttgat tgagaagatt
      241 tctatgaccg atattgctca tcagctggcc atttcaactt caactgtcat tcgcaagctc
      301 aatgattctc actttgagca tgatttttcg cgtcttcctg agattatgtc ctgggacgtt
      361 gaaacagtcc ggggagtgac tgtttcaatc gggagatgga gatgagcttt attgcgcaag
      421 attttaacaa tctcaatatc atcactgttc ttgaaggtag aacacaagct gtcatccgag
      481 atcactttct taaatatgat agagccgtcc gatgtcgcgt caaaatcatt actatggata
      541 tgtttagtcc ttactatgac ttagctagac aacttttccc gtgtgctaaa atcgttcttg
      601 atcgctttca cattgtacaa catcttagcc gtgctatgag tcgtgtgcgt gttcaaatca
      661 tgaatcagtt tcatcga
//
LOCUS       DBEROT010000095          579 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.95, whole genome shotgun sequence.
ACCESSION   DBEROT010000095 DBEROT010000000
VERSION     DBEROT010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..579
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.95"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>579
                     /locus_tag="ACL8CG_002146"
     CDS             <1..>579
                     /locus_tag="ACL8CG_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGS1344654.1"
                     /translation="HGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFN
                     QLLFRMDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHS
                     AYSETLYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQA
                     ENFIKEMKEGFFGDKTDSSTLIKNEVRMMMSCI"
BASE COUNT          165 a          128 c          121 g          165 t
ORIGIN      
        1 catggctatc atcctcttta tgctttcgag gggaagacag gttattgttt caatgcccag
       61 cttcgtcctg gtaatcgtta ttgttctgaa gaggcagaca gctttatcac acctgtttta
      121 gaacggttta atcaacttct ctttcgaatg gatagtggct ttgcgacccc aaaattatac
      181 gatttaattg aaaaaacagg gcaatactac ctcataaaac tcaagaaaaa tactgttctg
      241 agccgtcttg gagacctttc cctcccttgc ccacaggatg aggacttaac catcttgccc
      301 cactccgcct actcagaaac tctctatcaa gcaggatctt ggtcgcacaa gcgtcgtgtc
      361 tgccagttct ctgaacgaaa agaaggaaac ttgttctacg atgttatttc tctcgttaca
      421 aatatgacga gtggaacaag ccaagaccag tttcagcttt atcgtggacg tggtcaagcc
      481 gagaatttca tcaaggagat gaaggaggga ttttttggcg ataaaacgga tagttcaacc
      541 ttaatcaaaa acgaagttcg tatgatgatg agctgtatc
//
LOCUS       DBEROT010000096          538 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.96, whole genome shotgun sequence.
ACCESSION   DBEROT010000096 DBEROT010000000
VERSION     DBEROT010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.96"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..261
                     /locus_tag="ACL8CG_002147"
     CDS             <1..261
                     /locus_tag="ACL8CG_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1344655.1"
                     /translation="TDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNS
                     SSSQTNILAQLMDFFTGNGHLEDLSKISEPEALYAYIAEATA"
     gene            299..>538
                     /locus_tag="ACL8CG_002148"
     CDS             299..>538
                     /locus_tag="ACL8CG_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1344656.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRI"
BASE COUNT          172 a          102 c          103 g          161 t
ORIGIN      
        1 acagatattg ttcataattt ggctgaaaaa gttgtggtcg ttcgattaga gaaaccggtg
       61 actttccata atatgattgc gccagataag gaagtagaag tatccttgct cttctttatc
      121 attaataatt caagttcaag tcaaacgaac attcttgctc agttaatgga cttcttcaca
      181 ggaaatggtc atcttgaaga cctatcaaaa atttctgaac cagaagccct ttatgcttac
      241 attgctgaag caaccgctta atcttgtcta ttaaaaaata aaatcggagg aaatccaaat
      301 gattaaaatt cttgctgcct gcggtgcagg tgttaactca agtcaccaaa ttaaaagtgc
      361 tctagaagaa gaactttcaa accgtggtta cgatgttcac tgtgatgcag ttatggtgaa
      421 agatgtaaac gaagacctta tgaaaggtta cgatatcttt acaccaatcg ctgcaacaga
      481 ccttggtttt gaaccaggta tcccagttat cgaagctggg ccaatcttat tccgtatc
//
LOCUS       DBEROT010000097          485 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.97, whole genome shotgun sequence.
ACCESSION   DBEROT010000097 DBEROT010000000
VERSION     DBEROT010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.97"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..436
                     /locus_tag="ACL8CG_002149"
                     /pseudo
     CDS             1..436
                     /locus_tag="ACL8CG_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          167 a           79 c           92 g          147 t
ORIGIN      
        1 tcttctcata aaggagacgt tggtaagaag gcagagaatc tcattcaagg ccaatttgaa
       61 ggctctaaaa caatggaaaa gtgctacaca gatgtgactg aatttgccat tccagcaagt
      121 actcaaaagc tttacttatc accagtttta gatggcttta acagcgaaat tattgctttt
      181 aatctttctt gttcgtctaa tttagaacaa gtacaaacaa tgttggaaca ggcattcaca
      241 gagaagcact atggtggagt ccttctttgg gattctgaaa tcggaaatgt tttatggcta
      301 tgagaaaaca tttaaatcac ttaatcaatt ggaacaagct attatagact atattgatta
      361 ttacaacaac aagagaatta aggtaaaact aaaaggactt agccctgtgc aatacagaac
      421 taaatccttc ggataaatta attgtctaac tgtttggggt gcagtacaga actggcgttt
      481 tattt
//
LOCUS       DBEROT010000098          385 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.98, whole genome shotgun sequence.
ACCESSION   DBEROT010000098 DBEROT010000000
VERSION     DBEROT010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.98"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>385
                     /locus_tag="ACL8CG_002150"
     CDS             <1..>385
                     /locus_tag="ACL8CG_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleoside triphosphate hydrolase"
                     /protein_id="HGS1344657.1"
                     /translation="EDDTAALQNKLATKKAELEKTQKELDAALNELGPDGDEEETPAP
                     APQPEQPAPAPKPEQPTPAPKPEQPTPAPKPEQPAPAPKPEQPAPAPKPEQPAPAPKP
                     EQPTPAPKTGWKQENGMWYFYNTDGS"
BASE COUNT          146 a          113 c           67 g           59 t
ORIGIN      
        1 ctgaagatga tactgctgct cttcaaaata aattagctac taaaaaagct gaattggaaa
       61 aaactcaaaa agaattagat gcagctctta atgagttagg ccctgatgga gatgaagaag
      121 aaactccagc gccggctcct caaccagagc aaccagctcc tgcaccaaaa ccagagcaac
      181 caactcctgc accaaaacca gagcaaccaa ctcctgcacc aaaaccagag caaccagctc
      241 ctgcaccaaa accagagcaa ccagctcctg caccaaaacc agagcaacca gctcctgcac
      301 caaaaccaga gcaaccaact cctgcaccaa aaacaggctg gaaacaagaa aacggtatgt
      361 ggtacttcta caatactgat ggttc
//
LOCUS       DBEROT010000099          364 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.99, whole genome shotgun sequence.
ACCESSION   DBEROT010000099 DBEROT010000000
VERSION     DBEROT010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.99"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
BASE COUNT          106 a           45 c           77 g          136 t
ORIGIN      
        1 gaacagaatc ctctcttgat tgaagacaag ctagtcatta ggctggtttg tctttttgtc
       61 aactgtagtg ggttgatata atagtattag tgagtgggat aaaagtttca tttagtttat
      121 tcagtacaaa tttaacgggt caagatttat atactagtgg tgtttttggg gctgagagaa
      181 gtatcttgat tttatgtgtg gtttttatac ttacagttgt tctgctccaa agagcttgta
      241 gagaagaatt agctcataaa ggagattgat tattttgata tcaaaaaaat gcacaggata
      301 acctgatgca tttttttagc gacaatgctt gctacttcct tctgtcgaat ttagacaatt
      361 ttaa
//
LOCUS       DBEROT010000100          333 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 462685
            SAMN38107083-rid24773853.denovo.100, whole genome shotgun sequence.
ACCESSION   DBEROT010000100 DBEROT010000000
VERSION     DBEROT010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107083
            Sequence Read Archive: SRR26673286
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570514.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570514.1
            Genome Coverage       :: 243x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 14:54:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,150
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 66 of 140
            Pseudo Genes (incomplete)         :: 65 of 140
            Pseudo Genes (internal stop)      :: 52 of 140
            Pseudo Genes (multiple problems)  :: 39 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107083-rid24773853.denovo.100"
                     /strain="GPSC6"
                     /isolate="462685"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
BASE COUNT          109 a           42 c           36 g          146 t
ORIGIN      
        1 agttacttta taatagtgat aggtatcctt aattatttga attatttgaa atttatctaa
       61 ttttagagcg taatattatt ctttattact ttaaatctaa ccttcaattt caattataat
      121 gtgttgaatc cagagtagta cactgtagtt tctaaaaaat tagcttaaaa tggatgttaa
      181 gctccaattc atttgtttat atcttatttc agtttactat ataattaggt tttatttaat
      241 aatgttaaat agggagaact tttaaatcag ttctccctaa tatcatctct ttttaatttc
      301 ttcaattttt ataatagact tcctgcgaaa cca
//
